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Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
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336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
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299 KEGG pathways;
876 Reactome pathways;
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last scientific update:
11 Mar, 2019

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TPTE2

Gene Name TPTE2 (QuickGO)
Interactive visualization of TPTE2 structures
(A quick tutorial to explore the interactive visualization)

Synonyms TPTE2, TPIP
Protein Name TPTE2
Alternative Name(s)
 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2;3.1.3.67;Lipid phosphatase TPIP;TPTE and PTEN homologous inositol lipid phosphatase;
EntrezGene ID93492   (Comparative Toxicogenomics)
UniProt AC (Human) Q6XPS3 (protein sequence)
Enzyme ClassEC 3.1.3.67 (BRENDA )
Molecular Weight61112 Dalton
Protein Length522 amino acids (AA)
Genome Browsers NCBI | ENSG00000132958 (Ensembl) | UCSC
Crosslinking annotationsQuery our ID-mapping table
OrthologuesQuest For Orthologues (QFO) | GeneTree
ClassificationSuperfamily: Class I Cys-based PTPs --> Family: DSP --> Subfamily: PTEN-like | Historic class: Class I Cys-based PTPs --> VH1-like or DSPs --> PTENs | CATH ID: 3.90.190.10 | SCOP Fold: CC1
Phosphatase activityactive | Catalytic signature motif: HCKGGKGR
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)

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