Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
ROS1	10261	COSM20590,	stomach	carcinoma	p.F2138S	Substitution - Missense	6:117310102-117310102,	PATHOGENIC	0.99646	Info_not_available
ROS1	10261	COSM20590,	stomach	carcinoma	p.F2138S	Substitution - Missense	6:117310102-117310102,	PATHOGENIC	0.99646	Info_not_available
ROS1	10261	COSM6929870,	ovary	carcinoma	p.S1986F	Substitution - Missense	6:117318236-117318236,	PATHOGENIC	0.99627	28481359
ROS1	10261	COSM6976619,	central_nervous_system	glioma	p.E2153K	Substitution - Missense	6:117308906-117308906,	PATHOGENIC	0.99555	28481359
ROS1	10261	COSM1072508,	stomach	carcinoma	p.W2145L	Substitution - Missense	6:117310081-117310081,	PATHOGENIC	0.99543	26489445
ROS1	10261	COSM5902806,	NS	malignant_melanoma	p.G2136R	Substitution - Missense	6:117310109-117310109,	PATHOGENIC	0.99479	28481359
ROS1	10261	COSM6976801,	central_nervous_system	glioma	p.G2136E	Substitution - Missense	6:117310108-117310108,	PATHOGENIC	0.99479	28481359
ROS1	10261	COSM6933977,	skin	malignant_melanoma	p.D2143N	Substitution - Missense	6:117310088-117310088,	PATHOGENIC	0.99479	28481359
ROS1	10261	COSM6972111,	lung	carcinoma	p.?	Unknown	6:117310080-117310080,	PATHOGENIC	0.99479	28481359
ROS1	10261	COSM6944372,	autonomic_ganglia	neuroblastoma	p.W2152L	Substitution - Missense	6:117308908-117308908,	PATHOGENIC	0.99219	28481359
ROS1	10261	COSM4992424,	skin	carcinoma	p.?	Unknown	6:117404279-117404279,	PATHOGENIC	0.99	25589618
ROS1	10261	COSM314883,	lung	carcinoma	p.P2187T	Substitution - Missense	6:117308804-117308804,	PATHOGENIC	0.98953	22941188
ROS1	10261	COSM5610520,	skin	malignant_melanoma	p.?	Unknown	6:117320031-117320031,	PATHOGENIC	0.98706	26343386
ROS1	10261	COSM5576148,	stomach	carcinoma	p.S2166Y	Substitution - Missense	6:117308866-117308866,	PATHOGENIC	0.98686	26489445
ROS1	10261	COSM6915338,	breast	carcinoma	p.Q2160*	Substitution - Nonsense	6:117308885-117308885,	PATHOGENIC	0.98673	28481359
ROS1	10261	COSM6915338,	skin	carcinoma	p.Q2160*	Substitution - Nonsense	6:117308885-117308885,	PATHOGENIC	0.98673	28481359
ROS1	10261	COSM6915338,	breast	carcinoma	p.Q2160*	Substitution - Nonsense	6:117308885-117308885,	PATHOGENIC	0.98673	28481359
ROS1	10261	COSM6951686,	NS	malignant_melanoma	p.A1978P	Substitution - Missense	6:117319876-117319876,	PATHOGENIC	0.98469	28481359
ROS1	10261	COSM6957218,	large_intestine	carcinoma	p.S708L	Substitution - Missense	6:117386891-117386891,	PATHOGENIC	0.98463	28481359
ROS1	10261	COSM5576234,	stomach	carcinoma	p.Y2110C	Substitution - Missense	6:117310186-117310186,	PATHOGENIC	0.98446	26489445
ROS1	10261	COSM4992422,	skin	carcinoma	p.S702F	Substitution - Missense	6:117386909-117386909,	PATHOGENIC	0.98424	25589618
ROS1	10261	COSM6919256,	large_intestine	carcinoma	p.E1974*	Substitution - Nonsense	6:117319888-117319888,	PATHOGENIC	0.98242	28481359
ROS1	10261	COSM6172042,	lung	carcinoma	p.G2066C	Substitution - Missense	6:117311057-117311057,	PATHOGENIC	0.98218	28481359
ROS1	10261	COSM6967830,	skin	carcinoma	p.S2166F	Substitution - Missense	6:117308866-117308866,	PATHOGENIC	0.98104	28481359
ROS1	10261	COSM6955034,	large_intestine	carcinoma	p.D709Y	Substitution - Missense	6:117386889-117386889,	PATHOGENIC	0.9797	28481359
ROS1	10261	COSM6975258,	skin	malignant_melanoma	p.E2071K	Substitution - Missense	6:117311042-117311042,	PATHOGENIC	0.97963	28481359
ROS1	10261	COSM6975258,	breast	carcinoma	p.E2071K	Substitution - Missense	6:117311042-117311042,	PATHOGENIC	0.97963	28481359
ROS1	10261	COSM95213,	lung	carcinoma	p.P198L	Substitution - Missense	6:117397101-117397101,	PATHOGENIC	0.97926	20668451
ROS1	10261	COSM6979530,	biliary_tract	carcinoma	p.F626L	Substitution - Missense	6:117387916-117387916,	PATHOGENIC	0.97752	28481359
ROS1	10261	COSM6977587,	pancreas	carcinoma	p.A1919D	Substitution - Missense	6:117321280-117321280,	PATHOGENIC	0.97569	28481359
ROS1	10261	COSM6913490,	skin	carcinoma	p.G2119E	Substitution - Missense	6:117310159-117310159,	PATHOGENIC	0.97555	28481359
ROS1	10261	COSM6913070,	skin	carcinoma	p.A1998T	Substitution - Missense	6:117318201-117318201,	PATHOGENIC	0.97544	28481359
ROS1	10261	COSM6969949,	lung	carcinoma	p.G430C	Substitution - Missense	6:117389821-117389821,	PATHOGENIC	0.97206	28481359
ROS1	10261	COSM6983822,	salivary_gland	carcinoma	p.G960R	Substitution - Missense	6:117365676-117365676,	PATHOGENIC	0.97175	28481359
ROS1	10261	COSM6973113,	central_nervous_system	glioma	p.R433K	Substitution - Missense	6:117389811-117389811,	PATHOGENIC	0.97097	28481359
ROS1	10261	COSM4511984,	large_intestine	carcinoma	p.S296F	Substitution - Missense	6:117394708-117394708,	PATHOGENIC	0.97077	28481359
ROS1	10261	COSM6938486,	large_intestine	carcinoma	p.Y1700H	Substitution - Missense	6:117337322-117337322,	PATHOGENIC	0.97077	28481359
ROS1	10261	COSM6919392,	soft_tissue	leiomyosarcoma	p.F518L	Substitution - Missense	6:117389557-117389557,	PATHOGENIC	0.9699	28481359
ROS1	10261	COSM6934400,	skin	malignant_melanoma	p.D2113N	Substitution - Missense	6:117310178-117310178,	PATHOGENIC	0.96854	28481359
ROS1	10261	COSM6934400,	skin	malignant_melanoma	p.D2113N	Substitution - Missense	6:117310178-117310178,	PATHOGENIC	0.96854	28481359
ROS1	10261	COSM1072623,	penis	carcinoma	p.R304I	Substitution - Missense	6:117394684-117394684,	PATHOGENIC	0.96806	28481359
ROS1	10261	COSM6909337,	skin	carcinoma	p.G816E	Substitution - Missense	6:117383366-117383366,	PATHOGENIC	0.96718	28481359
ROS1	10261	COSM3619824,	NS	malignant_melanoma	p.E1943K	Substitution - Missense	6:117319981-117319981,	PATHOGENIC	0.96706	28481359
ROS1	10261	COSM3619824,	skin	malignant_melanoma	p.E1943K	Substitution - Missense	6:117319981-117319981,	PATHOGENIC	0.96706	28481359
ROS1	10261	COSM6957400,	penis	carcinoma	p.P1282H	Substitution - Missense	6:117357813-117357813,	PATHOGENIC	0.96511	28481359
ROS1	10261	COSM6970470,	skin	malignant_melanoma	p.G1135R	Substitution - Missense	6:117360384-117360384,	PATHOGENIC	0.96378	28481359
ROS1	10261	COSM3857781,	skin	malignant_melanoma	p.E1974K	Substitution - Missense	6:117319888-117319888,	PATHOGENIC	0.96244	28481359
ROS1	10261	COSM5880243,	skin	malignant_melanoma	p.N2084K	Substitution - Missense	6:117310263-117310263,	PATHOGENIC	0.96225	25515853
ROS1	10261	COSM5880243,	skin	malignant_melanoma	p.N2084K	Substitution - Missense	6:117310263-117310263,	PATHOGENIC	0.96225	25515853
ROS1	10261	COSM6933412,	skin	malignant_melanoma	p.S373F	Substitution - Missense	6:117394208-117394208,	PATHOGENIC	0.96215	28481359
ROS1	10261	COSM150171,	soft_tissue	haemangioblastoma	p.D1776H	Substitution - Missense	6:117329369-117329369,	PATHOGENIC	0.96198	25589003
ROS1	10261	COSM6961801,	small_intestine	carcinoma	p.G430D	Substitution - Missense	6:117389820-117389820,	PATHOGENIC	0.96176	28481359
ROS1	10261	COSM6973282,	urinary_tract	carcinoma	p.S214I	Substitution - Missense	6:117397053-117397053,	PATHOGENIC	0.96159	28481359
ROS1	10261	COSM6971816,	large_intestine	carcinoma	p.L1209W	Substitution - Missense	6:117359831-117359831,	PATHOGENIC	0.96153	28481359
ROS1	10261	COSM4605278,	upper_aerodigestive_tract	carcinoma	p.T1308N	Substitution - Missense	6:117356847-117356847,	PATHOGENIC	0.96113	25056374
ROS1	10261	COSM4722425,	central_nervous_system	glioma	p.V2089M	Substitution - Missense	6:117310250-117310250,	PATHOGENIC	0.96025	28481359
ROS1	10261	COSM6943284,	urinary_tract	carcinoma	p.?	Unknown	6:117337171-117337171,	PATHOGENIC	0.95971	28481359
ROS1	10261	COSM6947209,	breast	carcinoma	p.Y382H	Substitution - Missense	6:117394182-117394182,	PATHOGENIC	0.95971	28481359
ROS1	10261	COSM6955363,	large_intestine	carcinoma	p.Q606H	Substitution - Missense	6:117387976-117387976,	PATHOGENIC	0.95947	28481359
ROS1	10261	COSM6955363,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q606H	Substitution - Missense	6:117387976-117387976,	PATHOGENIC	0.95947	28481359
ROS1	10261	COSM6982363,	lung	carcinoma	p.P561Q	Substitution - Missense	6:117389427-117389427,	PATHOGENIC	0.95899	28481359
ROS1	10261	COSM6960793,	large_intestine	carcinoma	p.L359P	Substitution - Missense	6:117394250-117394250,	PATHOGENIC	0.95875	28481359
ROS1	10261	COSM6968764,	NS	malignant_melanoma	p.R297K	Substitution - Missense	6:117394705-117394705,	PATHOGENIC	0.95866	28481359
ROS1	10261	COSM6927614,	central_nervous_system	glioma	p.W292*	Substitution - Nonsense	6:117394719-117394719,	PATHOGENIC	0.95866	28481359
ROS1	10261	COSM6942711,	soft_tissue	liposarcoma	p.S485P	Substitution - Missense	6:117389656-117389656,	PATHOGENIC	0.95715	28481359
ROS1	10261	COSM228087,	skin	carcinoma	p.S941F	Substitution - Missense	6:117365732-117365732,	PATHOGENIC	0.95712	28481359
ROS1	10261	COSM228087,	skin	malignant_melanoma	p.S941F	Substitution - Missense	6:117365732-117365732,	PATHOGENIC	0.95712	28481359
ROS1	10261	COSM6958545,	skin	malignant_melanoma	p.W142*	Substitution - Nonsense	6:117404293-117404293,	PATHOGENIC	0.95617	28481359
ROS1	10261	COSM6963477,	skin	carcinoma	p.S1570T	Substitution - Missense	6:117341594-117341594,	PATHOGENIC	0.95565	28481359
ROS1	10261	COSM6969220,	skin	malignant_melanoma	p.W170L	Substitution - Missense	6:117403207-117403207,	PATHOGENIC	0.95564	28481359
ROS1	10261	COSM6912725,	lung	carcinoma	p.Y338F	Substitution - Missense	6:117394313-117394313,	PATHOGENIC	0.95558	28481359
ROS1	10261	COSM6928349,	breast	carcinoma	p.S485Y	Substitution - Missense	6:117389655-117389655,	PATHOGENIC	0.9551	28481359
ROS1	10261	COSM6928251,	lung	carcinoma	p.P2206H	Substitution - Missense	6:117301090-117301090,	PATHOGENIC	0.95495	28481359
ROS1	10261	COSM421102,	cervix	carcinoma	p.P561L	Substitution - Missense	6:117389427-117389427,	PATHOGENIC	0.95391	28481359
ROS1	10261	COSM6964969,	skin	malignant_melanoma	p.T162P	Substitution - Missense	6:117403232-117403232,	PATHOGENIC	0.95383	28481359
ROS1	10261	COSM6939685,	skin	malignant_melanoma	p.G1007E	Substitution - Missense	6:117365158-117365158,	PATHOGENIC	0.95369	28481359
ROS1	10261	COSM6949193,	testis	germ_cell_tumour	p.L1928P	Substitution - Missense	6:117320025-117320025,	PATHOGENIC	0.95356	28481359
ROS1	10261	COSM5744897,	large_intestine	carcinoma	p.D375Y	Substitution - Missense	6:117394203-117394203,	PATHOGENIC	0.95298	28481359
ROS1	10261	COSM6975272,	biliary_tract	carcinoma	p.C1815Y	Substitution - Missense	6:117326337-117326337,	PATHOGENIC	0.9518	28481359
ROS1	10261	COSM3157686,	skin	malignant_melanoma	p.E1933K	Substitution - Missense	6:117320011-117320011,	PATHOGENIC	0.95152	28481359
ROS1	10261	COSM3157780,	central_nervous_system	glioma	p.R1286H	Substitution - Missense	6:117356913-117356913,	PATHOGENIC	0.951	28481359
ROS1	10261	COSM3157780,	central_nervous_system	glioma	p.R1286H	Substitution - Missense	6:117356913-117356913,	PATHOGENIC	0.951	28481359
ROS1	10261	COSM6918730,	upper_aerodigestive_tract	carcinoma	p.W1069R	Substitution - Missense	6:117362779-117362779,	PATHOGENIC	0.95091	28481359
ROS1	10261	COSM6912720,	genital_tract	germ_cell_tumour	p.T1030R	Substitution - Missense	6:117365089-117365089,	PATHOGENIC	0.9507	28481359
ROS1	10261	COSM6957398,	penis	carcinoma	p.E1359*	Substitution - Nonsense	6:117356695-117356695,	PATHOGENIC	0.95027	28481359
ROS1	10261	COSM6935800,	central_nervous_system	glioma	p.L1156F	Substitution - Missense	6:117359991-117359991,	PATHOGENIC	0.94894	28481359
ROS1	10261	COSM6946202,	large_intestine	carcinoma	p.E1905*	Substitution - Nonsense	6:117321323-117321323,	PATHOGENIC	0.94886	28481359
ROS1	10261	COSM6847981,	pleura	mesothelioma	p.W1644C	Substitution - Missense	6:117341282-117341282,	PATHOGENIC	0.94859	26928227
ROS1	10261	COSM6919076,	lung	carcinoma	p.Y713N	Substitution - Missense	6:117385850-117385850,	PATHOGENIC	0.94852	28481359
ROS1	10261	COSM6951765,	kidney	carcinoma	p.F383L	Substitution - Missense	6:117394177-117394177,	PATHOGENIC	0.94851	28481359
ROS1	10261	COSM6944160,	large_intestine	carcinoma	p.F248Y	Substitution - Missense	6:117396951-117396951,	PATHOGENIC	0.94362	28481359
ROS1	10261	COSM6952854,	lung	carcinoma	p.Y802C	Substitution - Missense	6:117383408-117383408,	PATHOGENIC	0.94313	28481359
ROS1	10261	COSM6946206,	large_intestine	carcinoma	p.E908*	Substitution - Nonsense	6:117366166-117366166,	PATHOGENIC	0.94303	28481359
ROS1	10261	COSM421100,	skin	malignant_melanoma	p.P194S	Substitution - Missense	6:117397114-117397114,	PATHOGENIC	0.94187	28481359
ROS1	10261	COSM421100,	skin	carcinoma	p.P194S	Substitution - Missense	6:117397114-117397114,	PATHOGENIC	0.94187	25589618
ROS1	10261	COSM421100,	skin	malignant_melanoma	p.P194S	Substitution - Missense	6:117397114-117397114,	PATHOGENIC	0.94187	28481359
ROS1	10261	COSM249553,	kidney	carcinoma	p.T1274K	Substitution - Missense	6:117357837-117357837,	PATHOGENIC	0.94149	22138691
ROS1	10261	COSM3619854,	NS	malignant_melanoma	p.P1154S	Substitution - Missense	6:117359997-117359997,	PATHOGENIC	0.94098	28481359
ROS1	10261	COSM6972922,	skin	carcinoma	p.G2031E	Substitution - Missense	6:117317186-117317186,	PATHOGENIC	0.94063	28481359
ROS1	10261	COSM6972922,	skin	carcinoma	p.G2031E	Substitution - Missense	6:117317186-117317186,	PATHOGENIC	0.94063	28481359
ROS1	10261	COSM227019,	breast	carcinoma	p.R2126W	Substitution - Missense	6:117310139-117310139,	PATHOGENIC	0.9403	28481359
ROS1	10261	COSM4992394,	skin	carcinoma	p.E2306D	Substitution - Missense	6:117288618-117288618,	PATHOGENIC	0.93984	25589618
ROS1	10261	COSM6970886,	lung	carcinoma	p.T116R	Substitution - Missense	6:117404371-117404371,	PATHOGENIC	0.9397	28481359
ROS1	10261	COSM6950888,	lung	carcinoma	p.W1361*	Substitution - Nonsense	6:117356688-117356688,	PATHOGENIC	0.93962	28481359
ROS1	10261	COSM6962624,	upper_aerodigestive_tract	carcinoma	p.D1255H	Substitution - Missense	6:117357895-117357895,	PATHOGENIC	0.93942	28481359
ROS1	10261	COSM6970314,	skin	malignant_melanoma	p.E1359K	Substitution - Missense	6:117356695-117356695,	PATHOGENIC	0.93878	28481359
ROS1	10261	COSM6924186,	urinary_tract	carcinoma	p.H189D	Substitution - Missense	6:117403151-117403151,	PATHOGENIC	0.93816	28481359
ROS1	10261	COSM1440038,	large_intestine	carcinoma	p.E2201*	Substitution - Nonsense	6:117301106-117301106,	PATHOGENIC	0.93805	28481359
ROS1	10261	COSM6916948,	large_intestine	carcinoma	p.S932P	Substitution - Missense	6:117366094-117366094,	PATHOGENIC	0.9378	28481359
ROS1	10261	COSM6935944,	kidney	carcinoma	p.W142R	Substitution - Missense	6:117404294-117404294,	PATHOGENIC	0.93724	28481359
ROS1	10261	COSM6917189,	skin	malignant_melanoma	p.G484S	Substitution - Missense	6:117389659-117389659,	PATHOGENIC	0.93658	28481359
ROS1	10261	COSM1072614,	skin	carcinoma	p.R466Q	Substitution - Missense	6:117389712-117389712,	PATHOGENIC	0.93498	25589618
ROS1	10261	COSM6936886,	urinary_tract	carcinoma	p.G1824V	Substitution - Missense	6:117326310-117326310,	PATHOGENIC	0.93482	28481359
ROS1	10261	COSM6924385,	urinary_tract	carcinoma	p.Q132E	Substitution - Missense	6:117404324-117404324,	PATHOGENIC	0.93175	28481359
ROS1	10261	COSM6946200,	large_intestine	carcinoma	p.K2111N	Substitution - Missense	6:117310182-117310182,	PATHOGENIC	0.93049	28481359
ROS1	10261	COSM228085,	skin	malignant_melanoma	p.W1771*	Substitution - Nonsense	6:117329383-117329383,	PATHOGENIC	0.92886	26343386
ROS1	10261	COSM6911798,	large_intestine	carcinoma	p.F1085L	Substitution - Missense	6:117362729-117362729,	PATHOGENIC	0.92815	28481359
ROS1	10261	COSM6970472,	skin	malignant_melanoma	p.A921T	Substitution - Missense	6:117366127-117366127,	PATHOGENIC	0.92757	28481359
ROS1	10261	COSM6923165,	lung	carcinoma	p.T1670I	Substitution - Missense	6:117341205-117341205,	PATHOGENIC	0.92747	28481359
ROS1	10261	COSM1072629,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R245I	Substitution - Missense	6:117396960-117396960,	PATHOGENIC	0.92619	28481359
ROS1	10261	COSM6012443,	lung	carcinoma	p.F1940L	Substitution - Missense	6:117319988-117319988,	PATHOGENIC	0.92416	28481359
ROS1	10261	COSM6950121,	skin	malignant_melanoma	p.E290K	Substitution - Missense	6:117394727-117394727,	PATHOGENIC	0.92415	28481359
ROS1	10261	COSM6950121,	NS	malignant_melanoma	p.E290K	Substitution - Missense	6:117394727-117394727,	PATHOGENIC	0.92415	28481359
ROS1	10261	COSM6986398,	large_intestine	carcinoma	p.?	Unknown	6:117341312-117341312,	PATHOGENIC	0.92338	28481359
ROS1	10261	COSM6922406,	skin	malignant_melanoma	p.P255L	Substitution - Missense	6:117396930-117396930,	PATHOGENIC	0.92165	28481359
ROS1	10261	COSM6916051,	NS	malignant_melanoma	p.G1367R	Substitution - Missense	6:117356671-117356671,	PATHOGENIC	0.92146	28481359
ROS1	10261	COSM6950117,	skin	malignant_melanoma	p.G1556E	Substitution - Missense	6:117342402-117342402,	PATHOGENIC	0.92138	28481359
ROS1	10261	COSM6950684,	lung	carcinoma	p.L2053F	Substitution - Missense	6:117311094-117311094,	PATHOGENIC	0.92122	28481359
ROS1	10261	COSM6958853,	lung	carcinoma	p.W897C	Substitution - Missense	6:117366197-117366197,	PATHOGENIC	0.9195	28481359
ROS1	10261	COSM6984438,	endometrium	carcinoma	p.D457N	Substitution - Missense	6:117389740-117389740,	PATHOGENIC	0.91874	28481359
ROS1	10261	COSM6954300,	urinary_tract	carcinoma	p.I2109M	Substitution - Missense	6:117310188-117310188,	PATHOGENIC	0.91862	28481359
ROS1	10261	COSM5021097,	soft_tissue	haemangioblastoma	p.E1902K	Substitution - Missense	6:117321332-117321332,	PATHOGENIC	0.91817	25589003
ROS1	10261	COSM5021097,	skin	malignant_melanoma	p.E1902K	Substitution - Missense	6:117321332-117321332,	PATHOGENIC	0.91817	28481359
ROS1	10261	COSM5021097,	breast	carcinoma	p.E1902K	Substitution - Missense	6:117321332-117321332,	PATHOGENIC	0.91817	28481359
ROS1	10261	COSM5021097,	skin	carcinoma	p.E1902K	Substitution - Missense	6:117321332-117321332,	PATHOGENIC	0.91817	28481359
ROS1	10261	COSM6936915,	skin	carcinoma	p.G421E	Substitution - Missense	6:117393224-117393224,	PATHOGENIC	0.91683	28481359
ROS1	10261	COSM95212,	breast	carcinoma	p.I325N	Substitution - Missense	6:117394621-117394621,	PATHOGENIC	0.9168	20668451
ROS1	10261	COSM314887,	lung	carcinoma	p.G2237V	Substitution - Missense	6:117300997-117300997,	PATHOGENIC	0.91629	22941188
ROS1	10261	COSM6967344,	skin	malignant_melanoma	p.S1133Y	Substitution - Missense	6:117360389-117360389,	PATHOGENIC	0.916	28481359
ROS1	10261	COSM6940024,	skin	malignant_melanoma	p.G1025E	Substitution - Missense	6:117365104-117365104,	PATHOGENIC	0.91566	28481359
ROS1	10261	COSM4003668,	soft_tissue	haemangioblastoma	p.T145P	Substitution - Missense	6:117404285-117404285,	PATHOGENIC	0.914	25589003
ROS1	10261	COSM4003668,	soft_tissue	haemangioblastoma	p.T145P	Substitution - Missense	6:117404285-117404285,	PATHOGENIC	0.914	25589003
ROS1	10261	COSM4003668,	soft_tissue	haemangioblastoma	p.T145P	Substitution - Missense	6:117404285-117404285,	PATHOGENIC	0.914	25589003
ROS1	10261	COSM6984436,	endometrium	carcinoma	p.E874*	Substitution - Nonsense	6:117366268-117366268,	PATHOGENIC	0.9139	28481359
ROS1	10261	COSM6981200,	skin	malignant_melanoma	p.G2031R	Substitution - Missense	6:117317187-117317187,	PATHOGENIC	0.9129	28481359
ROS1	10261	COSM6924065,	lung	carcinoma	p.D2033N	Substitution - Missense	6:117317181-117317181,	PATHOGENIC	0.91243	28481359
ROS1	10261	COSM6970674,	upper_aerodigestive_tract	carcinoma	p.L1937V	Substitution - Missense	6:117319999-117319999,	PATHOGENIC	0.91232	28481359
ROS1	10261	COSM6923950,	central_nervous_system	glioma	p.D839N	Substitution - Missense	6:117379141-117379141,	PATHOGENIC	0.9117	28481359
ROS1	10261	COSM6940351,	urinary_tract	carcinoma	p.?	Unknown	6:117318253-117318253,	PATHOGENIC	0.9114	28481359
ROS1	10261	COSM6966132,	skin	malignant_melanoma	p.E874V	Substitution - Missense	6:117366267-117366267,	PATHOGENIC	0.91034	28481359
ROS1	10261	COSM5019790,	soft_tissue	haemangioblastoma	p.T1981T	Substitution - coding silent	6:117318250-117318250,	PATHOGENIC	0.9085	25589003
ROS1	10261	COSM6973826,	kidney	carcinoma	p.I745F	Substitution - Missense	6:117385754-117385754,	PATHOGENIC	0.90828	28481359
ROS1	10261	COSM6985972,	lung	carcinoma	p.G1764R	Substitution - Missense	6:117329405-117329405,	PATHOGENIC	0.90758	28481359
ROS1	10261	COSM5730810,	breast	other	p.S252T	Substitution - Missense	6:117396940-117396940,	PATHOGENIC	0.90282	26437033
ROS1	10261	COSM6953987,	lung	carcinoma	p.Q2317R	Substitution - Missense	6:117288586-117288586,	PATHOGENIC	0.90214	28481359
ROS1	10261	COSM76281,	large_intestine	carcinoma	p.S370Y	Substitution - Missense	6:117394217-117394217,	PATHOGENIC	0.89991	28481359
ROS1	10261	COSM6986425,	lung	carcinoma	p.F992L	Substitution - Missense	6:117365202-117365202,	PATHOGENIC	0.89981	28481359
ROS1	10261	COSM6976995,	lung	carcinoma	p.S418*	Substitution - Nonsense	6:117393233-117393233,	PATHOGENIC	0.89936	28481359
ROS1	10261	COSM6961196,	lung	carcinoma	p.D2189H	Substitution - Missense	6:117308798-117308798,	PATHOGENIC	0.89821	28481359
ROS1	10261	COSM6965416,	prostate	carcinoma	p.C1779F	Substitution - Missense	6:117329359-117329359,	PATHOGENIC	0.89719	28481359
ROS1	10261	COSM6912266,	skin	carcinoma	p.Q1409*	Substitution - Nonsense	6:117353086-117353086,	PATHOGENIC	0.89714	28481359
ROS1	10261	COSM6936888,	urinary_tract	carcinoma	p.L1204V	Substitution - Missense	6:117359847-117359847,	PATHOGENIC	0.89633	28481359
ROS1	10261	COSM6936888,	lung	carcinoma	p.L1204V	Substitution - Missense	6:117359847-117359847,	PATHOGENIC	0.89633	28481359
ROS1	10261	COSM6982546,	lung	carcinoma	p.R863G	Substitution - Missense	6:117379069-117379069,	PATHOGENIC	0.89628	28481359
ROS1	10261	COSM6931764,	central_nervous_system	glioma	p.?	Unknown	6:117409581-117409581,	PATHOGENIC	0.89502	28481359
ROS1	10261	COSM6918427,	soft_tissue	leiomyosarcoma	p.L2263S	Substitution - Missense	6:117288748-117288748,	PATHOGENIC	0.89396	28481359
ROS1	10261	COSM6980824,	endometrium	carcinoma	p.A1531V	Substitution - Missense	6:117342477-117342477,	PATHOGENIC	0.89195	28481359
ROS1	10261	COSM6931106,	skin	carcinoma	p.G140R	Substitution - Missense	6:117404300-117404300,	PATHOGENIC	0.89186	28481359
ROS1	10261	COSM6954807,	urinary_tract	carcinoma	p.S1768*	Substitution - Nonsense	6:117329392-117329392,	PATHOGENIC	0.89052	28481359
ROS1	10261	COSM6966341,	soft_tissue	angiosarcoma	p.P2007L	Substitution - Missense	6:117317258-117317258,	PATHOGENIC	0.89012	28481359
ROS1	10261	COSM3157660,	lung	carcinoma	p.R2072W	Substitution - Missense	6:117311039-117311039,	PATHOGENIC	0.88884	28481359
ROS1	10261	COSM6983631,	prostate	carcinoma	p.K500T	Substitution - Missense	6:117389610-117389610,	PATHOGENIC	0.88674	28481359
ROS1	10261	COSM6926802,	skin	malignant_melanoma	p.G1628E	Substitution - Missense	6:117341419-117341419,	PATHOGENIC	0.88595	28481359
ROS1	10261	COSM6926802,	NS	malignant_melanoma	p.G1628E	Substitution - Missense	6:117341419-117341419,	PATHOGENIC	0.88595	28481359
ROS1	10261	COSM6926802,	urinary_tract	carcinoma	p.G1628E	Substitution - Missense	6:117341419-117341419,	PATHOGENIC	0.88595	28481359
ROS1	10261	COSM6926802,	skin	malignant_melanoma	p.G1628E	Substitution - Missense	6:117341419-117341419,	PATHOGENIC	0.88595	28481359
ROS1	10261	COSM6926802,	skin	carcinoma	p.G1628E	Substitution - Missense	6:117341419-117341419,	PATHOGENIC	0.88595	28481359
ROS1	10261	COSM20591,	stomach	carcinoma	p.Y419H	Substitution - Missense	6:117393231-117393231,	PATHOGENIC	0.88565	Info_not_available
ROS1	10261	COSM20591,	stomach	carcinoma	p.Y419H	Substitution - Missense	6:117393231-117393231,	PATHOGENIC	0.88565	Info_not_available
ROS1	10261	COSM5020676,	soft_tissue	haemangioblastoma	p.E959E	Substitution - coding silent	6:117365677-117365677,	PATHOGENIC	0.88549	25589003
ROS1	10261	COSM6912033,	skin	malignant_melanoma	p.S1648N	Substitution - Missense	6:117341271-117341271,	PATHOGENIC	0.88539	28481359
ROS1	10261	COSM6946198,	large_intestine	carcinoma	p.D2256Y	Substitution - Missense	6:117288770-117288770,	PATHOGENIC	0.88513	28481359
ROS1	10261	COSM6984880,	large_intestine	carcinoma	p.G1201W	Substitution - Missense	6:117359856-117359856,	PATHOGENIC	0.88417	28481359
ROS1	10261	COSM6952472,	skin	malignant_melanoma	p.A2164V	Substitution - Missense	6:117308872-117308872,	PATHOGENIC	0.88406	28481359
ROS1	10261	COSM6977455,	lung	carcinoma	p.P675L	Substitution - Missense	6:117386990-117386990,	PATHOGENIC	0.88275	28481359
ROS1	10261	COSM6960567,	skin	carcinoma	p.A1362S	Substitution - Missense	6:117356686-117356686,	PATHOGENIC	0.88107	28481359
ROS1	10261	COSM6952051,	prostate	carcinoma	p.E92K	Substitution - Missense	6:117409597-117409597,	PATHOGENIC	0.88052	28481359
ROS1	10261	COSM5925307,	skin	carcinoma	p.Q1827*	Substitution - Nonsense	6:117326302-117326302,	PATHOGENIC	0.87966	28481359
ROS1	10261	COSM12910,	lung	carcinoma	p.Q865H	Substitution - Missense	6:117379061-117379061,	PATHOGENIC	0.87832	16140923
ROS1	10261	COSM12910,	lung	carcinoma	p.Q865H	Substitution - Missense	6:117379061-117379061,	PATHOGENIC	0.87832	16140923
ROS1	10261	COSM6926804,	skin	carcinoma	p.A446V	Substitution - Missense	6:117389772-117389772,	PATHOGENIC	0.87717	28481359
ROS1	10261	COSM6944685,	soft_tissue	leiomyosarcoma	p.D1391Y	Substitution - Missense	6:117353140-117353140,	PATHOGENIC	0.87685	28481359
ROS1	10261	COSM6950119,	skin	malignant_melanoma	p.S418L	Substitution - Missense	6:117393233-117393233,	PATHOGENIC	0.87664	28481359
ROS1	10261	COSM6950119,	skin	malignant_melanoma	p.S418L	Substitution - Missense	6:117393233-117393233,	PATHOGENIC	0.87664	28481359
ROS1	10261	COSM4992396,	skin	carcinoma	p.K2304N	Substitution - Missense	6:117288624-117288624,	PATHOGENIC	0.87628	25589618
ROS1	10261	COSM6980521,	endometrium	carcinoma	p.E1006D	Substitution - Missense	6:117365160-117365160,	PATHOGENIC	0.87549	28481359
ROS1	10261	COSM314879,	lung	carcinoma	p.A1043S	Substitution - Missense	6:117362857-117362857,	PATHOGENIC	0.87511	22941188
ROS1	10261	COSM6953786,	skin	carcinoma	p.?	Unknown	6:117341312-117341312,	PATHOGENIC	0.87456	28481359
ROS1	10261	COSM6768584,	NS	malignant_melanoma	p.R1592C	Substitution - Missense	6:117341528-117341528,	PATHOGENIC	0.87275	28481359
ROS1	10261	COSM6768584,	pancreas	carcinoma	p.R1592C	Substitution - Missense	6:117341528-117341528,	PATHOGENIC	0.87275	28481359
ROS1	10261	COSM20421,	large_intestine	carcinoma	p.K2003R	Substitution - Missense	6:117317270-117317270,	PATHOGENIC	0.87249	Info_not_available
ROS1	10261	COSM20421,	large_intestine	carcinoma	p.K2003R	Substitution - Missense	6:117317270-117317270,	PATHOGENIC	0.87249	Info_not_available
ROS1	10261	COSM6944053,	skin	carcinoma	p.I1304L	Substitution - Missense	6:117356860-117356860,	PATHOGENIC	0.86861	28481359
ROS1	10261	COSM1697837,	NS	malignant_melanoma	p.P437L	Substitution - Missense	6:117389799-117389799,	PATHOGENIC	0.86494	28481359
ROS1	10261	COSM109622,	skin	malignant_melanoma	p.S884F	Substitution - Missense	6:117366237-117366237,	PATHOGENIC	0.86396	28481359
ROS1	10261	COSM229019,	skin	carcinoma	p.R1035*	Substitution - Nonsense	6:117365075-117365075,	PATHOGENIC	0.86287	28481359
ROS1	10261	COSM6951463,	breast	carcinoma	p.L1016V	Substitution - Missense	6:117365132-117365132,	PATHOGENIC	0.86252	28481359
ROS1	10261	COSM6973794,	large_intestine	carcinoma	p.A1560T	Substitution - Missense	6:117341624-117341624,	PATHOGENIC	0.86231	28481359
ROS1	10261	COSM6931127,	skin	carcinoma	p.W803*	Substitution - Nonsense	6:117383405-117383405,	PATHOGENIC	0.86098	28481359
ROS1	10261	COSM6918130,	lung	carcinoma	p.V1557L	Substitution - Missense	6:117342400-117342400,	PATHOGENIC	0.85918	28481359
ROS1	10261	COSM6981925,	endometrium	carcinoma	p.R1910Q	Substitution - Missense	6:117321307-117321307,	PATHOGENIC	0.85711	28481359
ROS1	10261	COSM6918620,	skin	carcinoma	p.E1846V	Substitution - Missense	6:117326244-117326244,	PATHOGENIC	0.8538	28481359
ROS1	10261	COSM6980267,	central_nervous_system	glioma	p.R1035Q	Substitution - Missense	6:117365074-117365074,	PATHOGENIC	0.85379	28481359
ROS1	10261	COSM6937208,	skin	carcinoma	p.I1844F	Substitution - Missense	6:117326251-117326251,	PATHOGENIC	0.85178	28481359
ROS1	10261	COSM95208,	lung	carcinoma	p.Y891C	Substitution - Missense	6:117366216-117366216,	PATHOGENIC	0.85059	20668451
ROS1	10261	COSM4992400,	skin	carcinoma	p.K1766N	Substitution - Missense	6:117329397-117329397,	PATHOGENIC	0.84997	25589618
ROS1	10261	COSM95210,	lung	carcinoma	p.S716I	Substitution - Missense	6:117385840-117385840,	PATHOGENIC	0.84974	20668451
ROS1	10261	COSM6940353,	urinary_tract	carcinoma	p.D1100Y	Substitution - Missense	6:117362686-117362686,	PATHOGENIC	0.84931	28481359
ROS1	10261	COSM6935319,	endometrium	carcinoma	p.A265T	Substitution - Missense	6:117396251-117396251,	PATHOGENIC	0.84822	28481359
ROS1	10261	COSM5610508,	skin	malignant_melanoma	p.E1932K	Substitution - Missense	6:117320014-117320014,	PATHOGENIC	0.84648	26343386
ROS1	10261	COSM5610508,	salivary_gland	carcinoma	p.E1932K	Substitution - Missense	6:117320014-117320014,	PATHOGENIC	0.84648	28481359
ROS1	10261	COSM6925757,	urinary_tract	carcinoma	p.E1647K	Substitution - Missense	6:117341275-117341275,	PATHOGENIC	0.84387	28481359
ROS1	10261	COSM6925757,	urinary_tract	carcinoma	p.E1647K	Substitution - Missense	6:117341275-117341275,	PATHOGENIC	0.84387	28481359
ROS1	10261	COSM6913210,	lung	carcinoma	p.R167L	Substitution - Missense	6:117403216-117403216,	PATHOGENIC	0.84373	28481359
ROS1	10261	COSM6975876,	lung	carcinoma	p.N544I	Substitution - Missense	6:117389478-117389478,	PATHOGENIC	0.84291	28481359
ROS1	10261	COSM249317,	large_intestine	carcinoma	p.E2270K	Substitution - Missense	6:117288728-117288728,	PATHOGENIC	0.84279	28481359
ROS1	10261	COSM249317,	kidney	carcinoma	p.E2270K	Substitution - Missense	6:117288728-117288728,	PATHOGENIC	0.84279	22138691
ROS1	10261	COSM5610510,	skin	malignant_melanoma	p.G1869E	Substitution - Missense	6:117324367-117324367,	PATHOGENIC	0.84188	26343386
ROS1	10261	COSM40930,	central_nervous_system	glioma	p.?	Unknown	6:117344264-117344264,	PATHOGENIC	0.83912	18772396
ROS1	10261	COSM5592930,	eye	malignant_melanoma	p.P437S	Substitution - Missense	6:117389800-117389800,	PATHOGENIC	0.83637	28481359
ROS1	10261	COSM6922404,	skin	malignant_melanoma	p.G541R	Substitution - Missense	6:117389488-117389488,	PATHOGENIC	0.83637	28481359
ROS1	10261	COSM5562688,	prostate	carcinoma	p.P579L	Substitution - Missense	6:117389373-117389373,	PATHOGENIC	0.83575	28481359
ROS1	10261	COSM5562688,	prostate	carcinoma	p.P579L	Substitution - Missense	6:117389373-117389373,	PATHOGENIC	0.83575	28481359
ROS1	10261	COSM4992414,	skin	carcinoma	p.P1138S	Substitution - Missense	6:117360375-117360375,	PATHOGENIC	0.83479	25589618
ROS1	10261	COSM4992414,	skin	carcinoma	p.P1138S	Substitution - Missense	6:117360375-117360375,	PATHOGENIC	0.83479	25589618
ROS1	10261	COSM5730812,	breast	other	p.G531V	Substitution - Missense	6:117389517-117389517,	PATHOGENIC	0.83362	26437033
ROS1	10261	COSM6919260,	penis	carcinoma	p.E738D	Substitution - Missense	6:117385773-117385773,	PATHOGENIC	0.83356	28481359
ROS1	10261	COSM6919260,	large_intestine	carcinoma	p.E738D	Substitution - Missense	6:117385773-117385773,	PATHOGENIC	0.83356	28481359
ROS1	10261	COSM6924691,	bone	chondrosarcoma	p.T2266M	Substitution - Missense	6:117288739-117288739,	PATHOGENIC	0.83102	28481359
ROS1	10261	COSM6968385,	lung	carcinoma	p.D791G	Substitution - Missense	6:117383441-117383441,	PATHOGENIC	0.83074	28481359
ROS1	10261	COSM5020269,	soft_tissue	haemangioblastoma	p.A604A	Substitution - coding silent	6:117387982-117387982,	PATHOGENIC	0.83052	25589003
ROS1	10261	COSM6959301,	lung	carcinoma	p.I1352L	Substitution - Missense	6:117356716-117356716,	PATHOGENIC	0.83015	28481359
ROS1	10261	COSM95206,	lung	carcinoma	p.I2151F	Substitution - Missense	6:117308912-117308912,	PATHOGENIC	0.82881	20668451
ROS1	10261	COSM6913317,	skin	malignant_melanoma	p.S141R	Substitution - Missense	6:117404295-117404295,	PATHOGENIC	0.82473	28481359
ROS1	10261	COSM5890218,	skin	carcinoma	p.G1809E	Substitution - Missense	6:117326355-117326355,	PATHOGENIC	0.82437	28481359
ROS1	10261	COSM6970474,	skin	malignant_melanoma	p.P184L	Substitution - Missense	6:117403165-117403165,	PATHOGENIC	0.82263	28481359
ROS1	10261	COSM5576057,	stomach	carcinoma	p.T1735M	Substitution - Missense	6:117337216-117337216,	PATHOGENIC	0.82148	26489445
ROS1	10261	COSM6938658,	large_intestine	carcinoma	p.H555R	Substitution - Missense	6:117389445-117389445,	PATHOGENIC	0.82094	28481359
ROS1	10261	COSM6979091,	lung	carcinoid-endocrine_tumour	p.E94A	Substitution - Missense	6:117409590-117409590,	PATHOGENIC	0.81627	28481359
ROS1	10261	COSM3619830,	central_nervous_system	glioma	p.G1627D	Substitution - Missense	6:117341422-117341422,	PATHOGENIC	0.81493	28481359
ROS1	10261	COSM6943986,	stomach	carcinoma	p.S121Y	Substitution - Missense	6:117404356-117404356,	PATHOGENIC	0.8145	28481359
ROS1	10261	COSM6950893,	skin	carcinoma	p.S2002N	Substitution - Missense	6:117318188-117318188,	PATHOGENIC	0.81295	28481359
ROS1	10261	COSM6950893,	genital_tract	germ_cell_tumour	p.S2002N	Substitution - Missense	6:117318188-117318188,	PATHOGENIC	0.81295	28481359
ROS1	10261	COSM6944956,	stomach	carcinoma	p.N2185K	Substitution - Missense	6:117308808-117308808,	PATHOGENIC	0.81012	28481359
ROS1	10261	COSM229017,	skin	malignant_melanoma	p.S1768L	Substitution - Missense	6:117329392-117329392,	PATHOGENIC	0.80984	26343386
ROS1	10261	COSM6973544,	breast	carcinoma	p.L510F	Substitution - Missense	6:117389581-117389581,	PATHOGENIC	0.80591	28481359
ROS1	10261	COSM6983819,	salivary_gland	carcinoma	p.E1737D	Substitution - Missense	6:117337209-117337209,	PATHOGENIC	0.80282	28481359
ROS1	10261	COSM6963215,	skin	malignant_melanoma	p.G1616E	Substitution - Missense	6:117341455-117341455,	PATHOGENIC	0.8026	28481359
ROS1	10261	COSM6975799,	skin	carcinoma	p.S570F	Substitution - Missense	6:117389400-117389400,	PATHOGENIC	0.79868	28481359
ROS1	10261	COSM6967009,	large_intestine	carcinoma	p.A876T	Substitution - Missense	6:117366262-117366262,	PATHOGENIC	0.79634	28481359
ROS1	10261	COSM6967653,	skin	carcinoma	p.P2202S	Substitution - Missense	6:117301103-117301103,	PATHOGENIC	0.79187	28481359
ROS1	10261	COSM6916053,	NS	malignant_melanoma	p.A73V	Substitution - Missense	6:117416268-117416268,	PATHOGENIC	0.79035	28481359
ROS1	10261	COSM6915106,	lung	carcinoma	p.V785L	Substitution - Missense	6:117383460-117383460,	PATHOGENIC	0.78984	28481359
ROS1	10261	COSM5610512,	skin	malignant_melanoma	p.N1767K	Substitution - Missense	6:117329394-117329394,	PATHOGENIC	0.78961	26343386
ROS1	10261	COSM5019315,	soft_tissue	haemangioblastoma	p.R167Q	Substitution - Missense	6:117403216-117403216,	PATHOGENIC	0.78684	25589003
ROS1	10261	COSM5019315,	soft_tissue	haemangioblastoma	p.R167Q	Substitution - Missense	6:117403216-117403216,	PATHOGENIC	0.78684	25589003
ROS1	10261	COSM5019315,	soft_tissue	haemangioblastoma	p.R167Q	Substitution - Missense	6:117403216-117403216,	PATHOGENIC	0.78684	25589003
ROS1	10261	COSM5019315,	soft_tissue	haemangioblastoma	p.R167Q	Substitution - Missense	6:117403216-117403216,	PATHOGENIC	0.78684	25589003
ROS1	10261	COSM6355496,	skin	carcinoma	p.G42S	Substitution - Missense	6:117418506-117418506,	PATHOGENIC	0.78353	28481359
ROS1	10261	COSM6982204,	lung	carcinoma	p.Y1353S	Substitution - Missense	6:117356712-117356712,	PATHOGENIC	0.77998	28481359
ROS1	10261	COSM6921694,	soft_tissue	desmoplastic_small_round_cell_tumour	p.L993S	Substitution - Missense	6:117365200-117365200,	PATHOGENIC	0.77846	28481359
ROS1	10261	COSM6922486,	large_intestine	carcinoma	p.Q1114R	Substitution - Missense	6:117362643-117362643,	PATHOGENIC	0.77127	28481359
ROS1	10261	COSM5610515,	skin	malignant_melanoma	p.E1772K	Substitution - Missense	6:117329381-117329381,	PATHOGENIC	0.77107	26343386
ROS1	10261	COSM6930218,	ovary	low_malignant_potential_(borderline)_tumour	p.G798V	Substitution - Missense	6:117383420-117383420,	PATHOGENIC	0.77056	28481359
ROS1	10261	COSM5020363,	soft_tissue	haemangioblastoma	p.F1439S	Substitution - Missense	6:117352995-117352995,	PATHOGENIC	0.76862	25589003
ROS1	10261	COSM6982932,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.G777E	Substitution - Missense	6:117383483-117383483,	PATHOGENIC	0.7676	28481359
ROS1	10261	COSM6972823,	adrenal_gland	adrenal_cortical_carcinoma	p.E88*	Substitution - Nonsense	6:117409609-117409609,	PATHOGENIC	0.76602	28481359
ROS1	10261	COSM6941483,	autonomic_ganglia	neuroblastoma	p.K461N	Substitution - Missense	6:117389726-117389726,	PATHOGENIC	0.76535	28481359
ROS1	10261	COSM6943145,	skin	malignant_melanoma	p.P1679S	Substitution - Missense	6:117341179-117341179,	PATHOGENIC	0.76307	28481359
ROS1	10261	COSM6961198,	lung	carcinoma	p.Q772L	Substitution - Missense	6:117383498-117383498,	PATHOGENIC	0.75903	28481359
ROS1	10261	COSM6957170,	skin	malignant_melanoma	p.E274D	Substitution - Missense	6:117396222-117396222,	PATHOGENIC	0.75861	28481359
ROS1	10261	COSM6984434,	endometrium	carcinoma	p.R894W	Substitution - Missense	6:117366208-117366208,	PATHOGENIC	0.75785	28481359
ROS1	10261	COSM6986580,	soft_tissue	angiosarcoma	p.M1299I	Substitution - Missense	6:117356873-117356873,	PATHOGENIC	0.75603	28481359
ROS1	10261	COSM6963936,	lung	carcinoma	p.G367V	Substitution - Missense	6:117394226-117394226,	PATHOGENIC	0.74547	28481359
ROS1	10261	COSM6984428,	endometrium	carcinoma	p.G2158A	Substitution - Missense	6:117308890-117308890,	PATHOGENIC	0.74453	28481359
ROS1	10261	COSM6982000,	kidney	carcinoma	p.K1583M	Substitution - Missense	6:117341554-117341554,	PATHOGENIC	0.74144	28481359
ROS1	10261	COSM483322,	skin	carcinoma	p.I1514M	Substitution - Missense	6:117342527-117342527,	PATHOGENIC	0.7395	25589618
ROS1	10261	COSM6946686,	upper_aerodigestive_tract	carcinoma	p.I1276L	Substitution - Missense	6:117357832-117357832,	PATHOGENIC	0.73825	28481359
ROS1	10261	COSM6966043,	skin	adnexal_tumour	p.G1764E	Substitution - Missense	6:117329404-117329404,	PATHOGENIC	0.73742	28481359
ROS1	10261	COSM4604501,	upper_aerodigestive_tract	carcinoma	p.C57Y	Substitution - Missense	6:117416316-117416316,	PATHOGENIC	0.72833	25056374
ROS1	10261	COSM6950736,	skin	malignant_melanoma	p.G1973R	Substitution - Missense	6:117319891-117319891,	PATHOGENIC	0.72413	28481359
ROS1	10261	COSM6950736,	NS	malignant_melanoma	p.G1973R	Substitution - Missense	6:117319891-117319891,	PATHOGENIC	0.72413	28481359
ROS1	10261	COSM6917304,	breast	carcinoma	p.T837A	Substitution - Missense	6:117379147-117379147,	PATHOGENIC	0.72315	28481359
ROS1	10261	COSM96198,	ovary	other	p.F248F	Substitution - coding silent	6:117396950-117396950,	PATHOGENIC	0.72191	20668451
ROS1	10261	COSM1645376,	large_intestine	carcinoma	p.S914N	Substitution - Missense	6:117366147-117366147,	PATHOGENIC	0.72046	23700467
ROS1	10261	COSM6963317,	skin	carcinoma	p.E1744K	Substitution - Missense	6:117337190-117337190,	PATHOGENIC	0.71947	28481359
ROS1	10261	COSM6919957,	breast	carcinoma	p.D1192G	Substitution - Missense	6:117359882-117359882,	PATHOGENIC	0.71937	28481359
ROS1	10261	COSM6966128,	skin	malignant_melanoma	p.D2314N	Substitution - Missense	6:117288596-117288596,	PATHOGENIC	0.71922	28481359
ROS1	10261	COSM6966128,	upper_aerodigestive_tract	carcinoma	p.D2314N	Substitution - Missense	6:117288596-117288596,	PATHOGENIC	0.71922	28481359
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM3736400,	soft_tissue	haemangioblastoma	p.D2213N	Substitution - Missense	6:117301070-117301070,	PATHOGENIC	0.71879	25589003
ROS1	10261	COSM5915585,	skin	malignant_melanoma	p.D1854N	Substitution - Missense	6:117324413-117324413,	PATHOGENIC	0.71768	28481359
ROS1	10261	COSM5915585,	eye	malignant_melanoma	p.D1854N	Substitution - Missense	6:117324413-117324413,	PATHOGENIC	0.71768	28481359
ROS1	10261	COSM6930532,	soft_tissue	angiosarcoma	p.D393N	Substitution - Missense	6:117393309-117393309,	PATHOGENIC	0.71235	28481359
ROS1	10261	COSM6952217,	large_intestine	carcinoma	p.K1887N	Substitution - Missense	6:117321375-117321375,	PATHOGENIC	0.71103	28481359
ROS1	10261	COSM5575897,	stomach	carcinoma	p.L30*	Substitution - Nonsense	6:117425568-117425568,	PATHOGENIC	0.70796	26489445
ROS1	10261	COSM3157707,	skin	malignant_melanoma	p.L1786F	Substitution - Missense	6:117329339-117329339,	PATHOGENIC	0.70361	28481359
ROS1	10261	COSM6948762,	large_intestine	carcinoma	p.E1548D	Substitution - Missense	6:117342425-117342425,	PATHOGENIC	0.70245	28481359
ROS1	10261	COSM6970468,	skin	malignant_melanoma	p.S1213F	Substitution - Missense	6:117359819-117359819,	PATHOGENIC	0.70188	28481359
ROS1	10261	COSM6927612,	central_nervous_system	glioma	p.P659L	Substitution - Missense	6:117387818-117387818,	PATHOGENIC	0.70104	28481359
ROS1	10261	COSM6949901,	lung	carcinoma	p.R2179I	Substitution - Missense	6:117308827-117308827,	PATHOGENIC	0.70083	28481359
ROS1	10261	COSM1072611,	endometrium	carcinoma	p.E539*	Substitution - Nonsense	6:117389494-117389494,	PATHOGENIC	0.70066	28481359
ROS1	10261	COSM3619918,	liver	carcinoma	p.G126E	Substitution - Missense	6:117404341-117404341,	NEUTRAL	0.47575	28481359
ROS1	10261	COSM6963475,	skin	carcinoma	p.D2347E	Substitution - Missense	6:117288495-117288495,	NEUTRAL	0.4649	28481359
ROS1	10261	COSM1720290,	skin	malignant_melanoma	p.S1705L	Substitution - Missense	6:117337306-117337306,	NEUTRAL	0.45848	28481359
ROS1	10261	COSM6932777,	lung	carcinoma	p.T454R	Substitution - Missense	6:117389748-117389748,	NEUTRAL	0.44814	28481359
ROS1	10261	COSM6944616,	pancreas	carcinoma	p.L1672V	Substitution - Missense	6:117341200-117341200,	NEUTRAL	0.44448	28481359
ROS1	10261	COSM4722435,	endometrium	carcinoma	p.E1244K	Substitution - Missense	6:117357928-117357928,	NEUTRAL	0.43507	28481359
ROS1	10261	COSM6913638,	central_nervous_system	glioma	p.V1970I	Substitution - Missense	6:117319900-117319900,	NEUTRAL	0.42341	28481359
ROS1	10261	COSM4968479,	skin	carcinoma	p.L820F	Substitution - Missense	6:117383355-117383355,	NEUTRAL	0.42338	28481359
ROS1	10261	COSM6944261,	large_intestine	carcinoma	p.Y1297D	Substitution - Missense	6:117356881-117356881,	NEUTRAL	0.41771	28481359
ROS1	10261	COSM6937741,	urinary_tract	carcinoma	p.T667A	Substitution - Missense	6:117387795-117387795,	NEUTRAL	0.39321	28481359
ROS1	10261	COSM6936059,	lung	carcinoma	p.S950F	Substitution - Missense	6:117365705-117365705,	NEUTRAL	0.39247	28481359
ROS1	10261	COSM6975793,	skin	carcinoma	p.T1405P	Substitution - Missense	6:117353098-117353098,	NEUTRAL	0.3865	28481359
ROS1	10261	COSM3619802,	NS	malignant_melanoma	p.M2264I	Substitution - Missense	6:117288744-117288744,	NEUTRAL	0.38633	28481359
ROS1	10261	COSM3619802,	skin	malignant_melanoma	p.M2264I	Substitution - Missense	6:117288744-117288744,	NEUTRAL	0.38633	28481359
ROS1	10261	COSM6913492,	skin	carcinoma	p.F1613L	Substitution - Missense	6:117341463-117341463,	NEUTRAL	0.376	28481359
ROS1	10261	COSM6980545,	large_intestine	carcinoma	p.R77W	Substitution - Missense	6:117409642-117409642,	NEUTRAL	0.37563	28481359
ROS1	10261	COSM6912204,	breast	carcinoma	p.L574V	Substitution - Missense	6:117389389-117389389,	NEUTRAL	0.36981	28481359
ROS1	10261	COSM6921289,	bone	osteosarcoma	p.S283C	Substitution - Missense	6:117396196-117396196,	NEUTRAL	0.36403	28481359
ROS1	10261	COSM6921289,	bone	osteosarcoma	p.S283C	Substitution - Missense	6:117396196-117396196,	NEUTRAL	0.36403	28481359
ROS1	10261	COSM6960273,	large_intestine	carcinoma	p.Y1696H	Substitution - Missense	6:117337334-117337334,	NEUTRAL	0.34905	28481359
ROS1	10261	COSM5538344,	NS	malignant_melanoma	p.G2290S	Substitution - Missense	6:117288668-117288668,	NEUTRAL	0.3354	28481359
ROS1	10261	COSM6878873,	NS	malignant_melanoma	p.E1541K	Substitution - Missense	6:117342448-117342448,	NEUTRAL	0.32809	28481359
ROS1	10261	COSM6921310,	lung	carcinoma	p.R493L	Substitution - Missense	6:117389631-117389631,	NEUTRAL	0.31248	28481359
ROS1	10261	COSM6962075,	skin	malignant_melanoma	p.Y1198H	Substitution - Missense	6:117359865-117359865,	NEUTRAL	0.30831	28481359
ROS1	10261	COSM6971458,	stomach	carcinoma	p.P1315L	Substitution - Missense	6:117356826-117356826,	NEUTRAL	0.30812	28481359
ROS1	10261	COSM6915285,	large_intestine	carcinoma	p.Q1173H	Substitution - Missense	6:117359938-117359938,	NEUTRAL	0.30283	28481359
ROS1	10261	COSM6952219,	large_intestine	carcinoma	p.T1473A	Substitution - Missense	6:117344167-117344167,	NEUTRAL	0.29894	28481359
ROS1	10261	COSM6924352,	breast	carcinoma	p.L2292V	Substitution - Missense	6:117288662-117288662,	NEUTRAL	0.29121	28481359
ROS1	10261	COSM450402,	urinary_tract	carcinoma	p.E596K	Substitution - Missense	6:117388008-117388008,	NEUTRAL	0.28645	28481359
ROS1	10261	COSM6946986,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.A1355V	Substitution - Missense	6:117356706-117356706,	NEUTRAL	0.28555	28481359
ROS1	10261	COSM6938923,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A1130V	Substitution - Missense	6:117360398-117360398,	NEUTRAL	0.27874	28481359
ROS1	10261	COSM6938923,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A1130V	Substitution - Missense	6:117360398-117360398,	NEUTRAL	0.27874	28481359
ROS1	10261	COSM6927409,	urinary_tract	carcinoma	p.Q1326E	Substitution - Missense	6:117356794-117356794,	NEUTRAL	0.26813	28481359
ROS1	10261	COSM4992420,	skin	carcinoma	p.G830G	Substitution - coding silent	6:117383323-117383323,	NEUTRAL	0.25789	25589618
ROS1	10261	COSM6966130,	skin	malignant_melanoma	p.F1613Y	Substitution - Missense	6:117341464-117341464,	NEUTRAL	0.2562	28481359
ROS1	10261	COSM6923952,	central_nervous_system	glioma	p.A347T	Substitution - Missense	6:117394287-117394287,	NEUTRAL	0.25112	28481359
ROS1	10261	COSM6966312,	breast	carcinoma	p.I460M	Substitution - Missense	6:117389729-117389729,	NEUTRAL	0.24644	28481359
ROS1	10261	COSM5582393,	NS	malignant_melanoma	p.E2285K	Substitution - Missense	6:117288683-117288683,	NEUTRAL	0.24555	28481359
ROS1	10261	COSM5610518,	skin	malignant_melanoma	p.L1872L	Substitution - coding silent	6:117324357-117324357,	NEUTRAL	0.24545	26343386
ROS1	10261	COSM6928027,	lung	carcinoma	p.V728L	Substitution - Missense	6:117385805-117385805,	NEUTRAL	0.24283	28481359
ROS1	10261	COSM6919262,	large_intestine	carcinoma	p.Q562H	Substitution - Missense	6:117389423-117389423,	NEUTRAL	0.21454	28481359
ROS1	10261	COSM4992398,	skin	carcinoma	p.P2182S	Substitution - Missense	6:117308819-117308819,	NEUTRAL	0.21274	25589618
ROS1	10261	COSM6984078,	large_intestine	carcinoma	p.L918F	Substitution - Missense	6:117366134-117366134,	NEUTRAL	0.21121	28481359
ROS1	10261	COSM6946204,	large_intestine	carcinoma	p.E1660D	Substitution - Missense	6:117341234-117341234,	NEUTRAL	0.20969	28481359
ROS1	10261	COSM6929414,	urinary_tract	carcinoma	p.S550L	Substitution - Missense	6:117389460-117389460,	NEUTRAL	0.20574	28481359
ROS1	10261	COSM6965347,	skin	malignant_melanoma	p.G1382E	Substitution - Missense	6:117353166-117353166,	NEUTRAL	0.20388	28481359
ROS1	10261	COSM6965347,	skin	malignant_melanoma	p.G1382E	Substitution - Missense	6:117353166-117353166,	NEUTRAL	0.20388	28481359
ROS1	10261	COSM6928615,	soft_tissue	gastrointestinal_stromal_tumour	p.I1514V	Substitution - Missense	6:117342529-117342529,	NEUTRAL	0.20334	28481359
ROS1	10261	COSM6951906,	salivary_gland	carcinoma	p.G1895R	Substitution - Missense	6:117321353-117321353,	NEUTRAL	0.20047	28481359
ROS1	10261	COSM6912369,	lung	carcinoma	p.G549D	Substitution - Missense	6:117389463-117389463,	NEUTRAL	0.19894	28481359
ROS1	10261	COSM6985326,	lung	carcinoma	p.W1550C	Substitution - Missense	6:117342419-117342419,	NEUTRAL	0.19594	28481359
ROS1	10261	COSM6963479,	skin	carcinoma	p.G1117S	Substitution - Missense	6:117362635-117362635,	NEUTRAL	0.18637	28481359
ROS1	10261	COSM3157801,	vulva	carcinoma	p.Q1091E	Substitution - Missense	6:117362713-117362713,	NEUTRAL	0.17959	28481359
ROS1	10261	COSM6909766,	breast	carcinoma	p.Q1889E	Substitution - Missense	6:117321371-117321371,	NEUTRAL	0.17499	28481359
ROS1	10261	COSM6930473,	NS	malignant_melanoma	p.L1503F	Substitution - Missense	6:117344075-117344075,	NEUTRAL	0.17464	28481359
ROS1	10261	COSM6954777,	soft_tissue	liposarcoma	p.A974V	Substitution - Missense	6:117365633-117365633,	NEUTRAL	0.17104	28481359
ROS1	10261	COSM6954777,	urinary_tract	carcinoma	p.A974V	Substitution - Missense	6:117365633-117365633,	NEUTRAL	0.17104	28481359
ROS1	10261	COSM1697825,	urinary_tract	carcinoma	p.E1605K	Substitution - Missense	6:117341489-117341489,	NEUTRAL	0.17074	28481359
ROS1	10261	COSM6768582,	lung	carcinoma	p.G1915R	Substitution - Missense	6:117321293-117321293,	NEUTRAL	0.16946	28481359
ROS1	10261	COSM6972153,	lung	carcinoma	p.S2299F	Substitution - Missense	6:117288640-117288640,	NEUTRAL	0.16601	28481359
ROS1	10261	COSM6947126,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.I4M	Substitution - Missense	6:117425645-117425645,	NEUTRAL	0.16428	28481359
ROS1	10261	COSM6963481,	skin	carcinoma	p.L564F	Substitution - Missense	6:117389419-117389419,	NEUTRAL	0.15707	28481359
ROS1	10261	COSM6910632,	prostate	carcinoma	p.Q26R	Substitution - Missense	6:117425580-117425580,	NEUTRAL	0.1568	28481359
ROS1	10261	COSM3619899,	skin	carcinoma	p.I529I	Substitution - coding silent	6:117389522-117389522,	NEUTRAL	0.15614	25589618
ROS1	10261	COSM6975797,	skin	carcinoma	p.L1013S	Substitution - Missense	6:117365140-117365140,	NEUTRAL	0.15232	28481359
ROS1	10261	COSM6945487,	NS	malignant_melanoma	p.L691I	Substitution - Missense	6:117386943-117386943,	NEUTRAL	0.15213	28481359
ROS1	10261	COSM4419092,	soft_tissue	haemangioblastoma	p.R2083R	Substitution - coding silent	6:117310268-117310268,	NEUTRAL	0.14675	25589003
ROS1	10261	COSM4419092,	soft_tissue	haemangioblastoma	p.R2083R	Substitution - coding silent	6:117310268-117310268,	NEUTRAL	0.14675	25589003
ROS1	10261	COSM4419092,	soft_tissue	haemangioblastoma	p.R2083R	Substitution - coding silent	6:117310268-117310268,	NEUTRAL	0.14675	25589003
ROS1	10261	COSM4419092,	soft_tissue	haemangioblastoma	p.R2083R	Substitution - coding silent	6:117310268-117310268,	NEUTRAL	0.14675	25589003
ROS1	10261	COSM6963706,	kidney	carcinoma	p.N1800I	Substitution - Missense	6:117326382-117326382,	NEUTRAL	0.14555	28481359
ROS1	10261	COSM6986497,	soft_tissue	gastrointestinal_stromal_tumour	p.N635H	Substitution - Missense	6:117387891-117387891,	NEUTRAL	0.14107	28481359
ROS1	10261	COSM95211,	breast	carcinoma	p.R560C	Substitution - Missense	6:117389431-117389431,	NEUTRAL	0.14044	20668451
ROS1	10261	COSM95211,	large_intestine	carcinoma	p.R560C	Substitution - Missense	6:117389431-117389431,	NEUTRAL	0.14044	28481359
ROS1	10261	COSM3697372,	ovary	carcinoma	p.G48D	Substitution - Missense	6:117418487-117418487,	NEUTRAL	0.13846	28481359
ROS1	10261	COSM6966534,	stomach	carcinoma	p.D435N	Substitution - Missense	6:117389806-117389806,	NEUTRAL	0.13784	28481359
ROS1	10261	COSM6930311,	urinary_tract	carcinoma	p.Q1797H	Substitution - Missense	6:117326390-117326390,	NEUTRAL	0.13728	28481359
ROS1	10261	COSM6942928,	lung	carcinoma	p.A1423S	Substitution - Missense	6:117353044-117353044,	NEUTRAL	0.12874	28481359
ROS1	10261	COSM6982027,	lung	carcinoma	p.H191Y	Substitution - Missense	6:117403145-117403145,	NEUTRAL	0.12748	28481359
ROS1	10261	COSM169762,	large_intestine	carcinoma	p.R2184I	Substitution - Missense	6:117308812-117308812,	NEUTRAL	0.11519	28481359
ROS1	10261	COSM169762,	large_intestine	carcinoma	p.R2184I	Substitution - Missense	6:117308812-117308812,	NEUTRAL	0.11519	28481359
ROS1	10261	COSM169762,	large_intestine	carcinoma	p.R2184I	Substitution - Missense	6:117308812-117308812,	NEUTRAL	0.11519	28481359
ROS1	10261	COSM3726791,	soft_tissue	haemangioblastoma	p.?	Unknown	6:117318256-117318256,	NEUTRAL	0.1123	25589003
ROS1	10261	COSM3726791,	soft_tissue	haemangioblastoma	p.?	Unknown	6:117318256-117318256,	NEUTRAL	0.1123	25589003
ROS1	10261	COSM3726791,	soft_tissue	haemangioblastoma	p.?	Unknown	6:117318256-117318256,	NEUTRAL	0.1123	25589003
ROS1	10261	COSM6980983,	lung	carcinoma	p.S1245*	Substitution - Nonsense	6:117357924-117357924,	NEUTRAL	0.11004	28481359
ROS1	10261	COSM4992416,	skin	carcinoma	p.G1055V	Substitution - Missense	6:117362820-117362820,	NEUTRAL	0.10988	25589618
ROS1	10261	COSM3619897,	skin	malignant_melanoma	p.P620L	Substitution - Missense	6:117387935-117387935,	NEUTRAL	0.10676	28481359
ROS1	10261	COSM6974863,	large_intestine	carcinoma	p.L1385F	Substitution - Missense	6:117353158-117353158,	NEUTRAL	0.10452	28481359
ROS1	10261	COSM6974863,	skin	carcinoma	p.L1385F	Substitution - Missense	6:117353158-117353158,	NEUTRAL	0.10452	28481359
ROS1	10261	COSM6969339,	large_intestine	carcinoma	p.W1477*	Substitution - Nonsense	6:117344154-117344154,	NEUTRAL	0.10064	28481359
ROS1	10261	COSM6941140,	NS	carcinoma	p.S819F	Substitution - Missense	6:117383357-117383357,	NEUTRAL	0.09175	28481359
ROS1	10261	COSM6941140,	NS	carcinoma	p.S819F	Substitution - Missense	6:117383357-117383357,	NEUTRAL	0.09175	28481359
ROS1	10261	COSM6941140,	upper_aerodigestive_tract	carcinoma	p.S819F	Substitution - Missense	6:117383357-117383357,	NEUTRAL	0.09175	28481359
ROS1	10261	COSM6934875,	central_nervous_system	glioma	p.Y1700S	Substitution - Missense	6:117337321-117337321,	NEUTRAL	0.09038	28481359
ROS1	10261	COSM6980648,	large_intestine	carcinoma	p.D1496Y	Substitution - Missense	6:117344098-117344098,	NEUTRAL	0.09027	28481359
ROS1	10261	COSM6980648,	large_intestine	carcinoma	p.D1496Y	Substitution - Missense	6:117344098-117344098,	NEUTRAL	0.09027	28481359
ROS1	10261	COSM4605976,	upper_aerodigestive_tract	carcinoma	p.S278I	Substitution - Missense	6:117396211-117396211,	NEUTRAL	0.08685	25056374
ROS1	10261	COSM6976089,	breast	carcinoma	p.E2330K	Substitution - Missense	6:117288548-117288548,	NEUTRAL	0.08509	28481359
ROS1	10261	COSM314881,	lung	carcinoma	p.T454T	Substitution - coding silent	6:117389747-117389747,	NEUTRAL	0.07993	22941188
ROS1	10261	COSM6768594,	pancreas	carcinoma	p.N2220I	Substitution - Missense	6:117301048-117301048,	NEUTRAL	0.07837	28481359
ROS1	10261	COSM6906577,	lung	carcinoma	p.A87V	Substitution - Missense	6:117409611-117409611,	NEUTRAL	0.06946	28481359
ROS1	10261	COSM5869188,	pancreas	carcinoma	p.P151L	Substitution - Missense	6:117403264-117403264,	NEUTRAL	0.06828	28481359
ROS1	10261	COSM6910557,	genital_tract	germ_cell_tumour	p.A410T	Substitution - Missense	6:117393258-117393258,	NEUTRAL	0.06596	28481359
ROS1	10261	COSM6975795,	skin	carcinoma	p.T1384I	Substitution - Missense	6:117353160-117353160,	NEUTRAL	0.06422	28481359
ROS1	10261	COSM6971661,	lung	carcinoma	p.R2230I	Substitution - Missense	6:117301018-117301018,	NEUTRAL	0.06351	28481359
ROS1	10261	COSM6974693,	large_intestine	carcinoma	p.E1348D	Substitution - Missense	6:117356726-117356726,	NEUTRAL	0.05863	28481359
ROS1	10261	COSM6957402,	penis	carcinoma	p.Q335H	Substitution - Missense	6:117394321-117394321,	NEUTRAL	0.05811	28481359
ROS1	10261	COSM6949826,	urinary_tract	carcinoma	p.L1347V	Substitution - Missense	6:117356731-117356731,	NEUTRAL	0.05506	28481359
ROS1	10261	COSM6940355,	urinary_tract	carcinoma	p.L11H	Substitution - Missense	6:117425625-117425625,	NEUTRAL	0.05296	28481359
ROS1	10261	COSM3157658,	large_intestine	carcinoma	p.R2072Q	Substitution - Missense	6:117311038-117311038,	NEUTRAL	0.05002	28481359
ROS1	10261	COSM4992412,	skin	carcinoma	p.R1425R	Substitution - coding silent	6:117353036-117353036,	NEUTRAL	0.04992	25589618
ROS1	10261	COSM1072620,	large_intestine	carcinoma	p.R360I	Substitution - Missense	6:117394247-117394247,	NEUTRAL	0.04942	28481359
ROS1	10261	COSM1697835,	NS	malignant_melanoma	p.E599K	Substitution - Missense	6:117387999-117387999,	NEUTRAL	0.04702	28481359
ROS1	10261	COSM277104,	large_intestine	carcinoma	p.D725N	Substitution - Missense	6:117385814-117385814,	NEUTRAL	0.04673	28481359
ROS1	10261	COSM277104,	small_intestine	carcinoma	p.D725N	Substitution - Missense	6:117385814-117385814,	NEUTRAL	0.04673	28481359
ROS1	10261	COSM4605047,	upper_aerodigestive_tract	carcinoma	p.D100D	Substitution - coding silent	6:117404418-117404418,	NEUTRAL	0.04524	25056374
ROS1	10261	COSM6984432,	endometrium	carcinoma	p.R1182I	Substitution - Missense	6:117359912-117359912,	NEUTRAL	0.0452	28481359
ROS1	10261	COSM6919258,	large_intestine	carcinoma	p.N1090K	Substitution - Missense	6:117362714-117362714,	NEUTRAL	0.04491	28481359
ROS1	10261	COSM6982916,	skin	carcinoma	p.N1322K	Substitution - Missense	6:117356804-117356804,	NEUTRAL	0.0449	28481359
ROS1	10261	COSM6923082,	soft_tissue	gastrointestinal_stromal_tumour	p.R1467*	Substitution - Nonsense	6:117344185-117344185,	NEUTRAL	0.04113	28481359
ROS1	10261	COSM5770343,	urinary_tract	carcinoma	p.V1418I	Substitution - Missense	6:117353059-117353059,	NEUTRAL	0.04094	28481359
ROS1	10261	COSM6927827,	lung	carcinoma	p.H1208N	Substitution - Missense	6:117359835-117359835,	NEUTRAL	0.04085	28481359
ROS1	10261	COSM3157756,	skin	carcinoma	p.R1425K	Substitution - Missense	6:117353037-117353037,	NEUTRAL	0.04047	25589618
ROS1	10261	COSM6912035,	skin	malignant_melanoma	p.P157S	Substitution - Missense	6:117403247-117403247,	NEUTRAL	0.03809	28481359
ROS1	10261	COSM4992403,	skin	malignant_melanoma	p.S1724L	Substitution - Missense	6:117337249-117337249,	NEUTRAL	0.0367	28481359
ROS1	10261	COSM4992403,	skin	carcinoma	p.S1724L	Substitution - Missense	6:117337249-117337249,	NEUTRAL	0.0367	25589618
ROS1	10261	COSM4992403,	skin	malignant_melanoma	p.S1724L	Substitution - Missense	6:117337249-117337249,	NEUTRAL	0.0367	28481359
ROS1	10261	COSM7325525,	biliary_tract	carcinoma	p.A410S	Substitution - Missense	6:117393258-117393258,	NEUTRAL	0.03507	29360550
ROS1	10261	COSM6976299,	NS	malignant_melanoma	p.P620S	Substitution - Missense	6:117387936-117387936,	NEUTRAL	0.03294	28481359
ROS1	10261	COSM6968480,	central_nervous_system	glioma	p.V1165I	Substitution - Missense	6:117359964-117359964,	NEUTRAL	0.03081	28481359
ROS1	10261	COSM6941244,	central_nervous_system	glioma	p.T1879I	Substitution - Missense	6:117324337-117324337,	NEUTRAL	0.03016	28481359
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM3761458,	soft_tissue	haemangioblastoma	p.K2228Q	Substitution - Missense	6:117301025-117301025,	NEUTRAL	0.02985	25589003
ROS1	10261	COSM6924637,	large_intestine	carcinoma	p.R902K	Substitution - Missense	6:117366183-117366183,	NEUTRAL	0.02846	28481359
ROS1	10261	COSM6949116,	skin	carcinoma	p.M2043I	Substitution - Missense	6:117317149-117317149,	NEUTRAL	0.02781	28481359
ROS1	10261	COSM6986298,	soft_tissue	gastrointestinal_stromal_tumour	p.M1527V	Substitution - Missense	6:117342490-117342490,	NEUTRAL	0.02767	28481359
ROS1	10261	COSM6984430,	endometrium	carcinoma	p.I1597V	Substitution - Missense	6:117341513-117341513,	NEUTRAL	0.02523	28481359
ROS1	10261	COSM3920644,	breast	carcinoma	p.L368I	Substitution - Missense	6:117394224-117394224,	NEUTRAL	0.01902	28481359
ROS1	10261	COSM5575769,	stomach	carcinoma	p.Y1722H	Substitution - Missense	6:117337256-117337256,	NEUTRAL	0.01533	26489445
ROS1	10261	COSM6978208,	endometrium	carcinoma	p.P9L	Substitution - Missense	6:117425631-117425631,	NEUTRAL	0.01431	28481359
ROS1	10261	COSM6913142,	large_intestine	carcinoma	p.V1002A	Substitution - Missense	6:117365173-117365173,	NEUTRAL	0.01421	28481359
ROS1	10261	COSM739499,	endometrium	carcinoma	p.A1459T	Substitution - Missense	6:117344209-117344209,	NEUTRAL	0.00914	28481359
ROS1	10261	COSM6928944,	central_nervous_system	glioma	p.S1306N	Substitution - Missense	6:117356853-117356853,	NEUTRAL	0.00728	28481359
ROS1	10261	COSM1072578,	large_intestine	carcinoma	p.R1212H	Substitution - Missense	6:117359822-117359822,	NEUTRAL	0.00717	28481359
ROS1	10261	COSM6936913,	skin	carcinoma	p.M643I	Substitution - Missense	6:117387865-117387865,	NEUTRAL	0.00601	28481359
ROS1	10261	COSM6944327,	large_intestine	carcinoma	p.V1187I	Substitution - Missense	6:117359898-117359898,	NEUTRAL	0.00331	28481359
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM3761456,	soft_tissue	haemangioblastoma	p.S2229C	Substitution - Missense	6:117301021-117301021,	NEUTRAL	0.00273	25589003
ROS1	10261	COSM5020347,	soft_tissue	haemangioblastoma	p.T1177T	Substitution - coding silent	6:117359926-117359926,	NEUTRAL	0.00219	25589003
ROS1	10261	COSM6985140,	endometrium	carcinoma	p.Y322H	Substitution - Missense	6:117394631-117394631,	NEUTRAL	0.00126	28481359
ROS1	10261	COSM5611384,	skin	malignant_melanoma	p.E1894K	Substitution - Missense	6:117321356-117321357,	Info_not_available	Info_not_available	26343386
ROS1	10261	COSM5977598,	central_nervous_system	glioma	p.R1129fs*5	Deletion - Frameshift	6:117360401-117360402,	Info_not_available	Info_not_available	26487540
ROS1	10261	COSM5576297,	stomach	carcinoma	p.G1117fs*2	Deletion - Frameshift	6:117362636-117362636,	Info_not_available	Info_not_available	26489445
ROS1	10261	COSM5019060, COSM5020191,	soft_tissue	haemangioblastoma	p.?, p.I537M	Substitution - Missense, Unknown	6:117326418-117326419, 6:117389498-117389498,	Info_not_available	0.68683, Info_not_available	25589003
ROS1	10261	COSM4603921, COSM4605370,	upper_aerodigestive_tract	carcinoma	p.A1443V, p.L936fs*10	Insertion - Frameshift, Substitution - Missense	6:117344256-117344256, 6:117366081-117366082,	Info_not_available	0.61068, Info_not_available	25056374
ROS1	10261	COSM4992406, COSM4992408, COSM4992410, COSM4992418,	skin	carcinoma	p.?, p.C854Y, p.E1605V, p.P1650L	Substitution - Missense, Unknown	6:117341134-117341134, 6:117341265-117341265, 6:117341488-117341488, 6:117379095-117379095,	Info_not_available	0.59697, .60535, .68089, .69913	25589618
ROS1	10261	COSM95207, COSM95209, COSM96197,	lung	carcinoma	p.D1225H, p.F727S, p.S2064S	Substitution - Missense, Substitution - coding silent	6:117311061-117311061, 6:117357985-117357985, 6:117385807-117385807,	Info_not_available	0.55962, .56851, .68105	20668451
ROS1	10261	COSM5024958, COSM5025023,	breast	carcinoma	p.A1515D, p.Y1700*	Substitution - Missense, Substitution - Nonsense	6:117337320-117337320, 6:117342525-117342525,	Info_not_available	0.55948, .64002	25850943
ROS1	10261	COSM1072593, COSM1072617, COSM1440072, COSM387704, COSM4166710, COSM6768615, COSM6910311, COSM6912185, COSM6914991, COSM6915582, COSM6916198, COSM6917803, COSM6920076, COSM6921151, COSM6921380, COSM6923236, COSM6927741, COSM6929374, COSM6931762, COSM6933979, COSM6935720, COSM6939114, COSM6939464, COSM6940064, COSM6941007, COSM6941224, COSM6941435, COSM6951034, COSM6953554, COSM6953788, COSM6954580, COSM6956288, COSM6957396, COSM6959063, COSM6965833, COSM6967149, COSM6968538, COSM6968834, COSM6971485, COSM6971663, COSM6976961, COSM6977286, COSM6978532, COSM6979324, COSM6979820, COSM6980381, COSM6980650, COSM6980861, COSM6982184, COSM6983383, COSM6983824, COSM6984106,	NS, breast, central_nervous_system, endometrium, large_intestine, lung, ovary, penis, prostate, salivary_gland, skin, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract	carcinoma, gastrointestinal_stromal_tumour, glioma, malignant_melanoma, sarcoma	p.?, p.A877S, p.A877T, p.A974fs*14, p.D1202fs*41, p.D2143fs*25, p.D319N, p.E1548K, p.E1589K, p.E2030L, p.E2296G, p.E395D, p.F1828fs*6, p.G1196fs*47, p.G1852*, p.G1852V, p.G222C, p.G2345E, p.G666S, p.I414fs*14, p.K238fs*2, p.K655E, p.L1167fs*26, p.L1284fs*1, p.L1600M, p.L1945fs*17, p.L2277V, p.L230F, p.M889I, p.N31T, p.P1044I, p.P1743S, p.P2325F, p.P973L, p.Q412*, p.Q572*, p.Q59H, p.R2269*, p.R380K, p.R863W, p.S2088F, p.S2297Y, p.S262C, p.S262F, p.S565L, p.T1606_E1612delTPLRQSE, p.T2176A, p.T480A, p.V1435I, p.Y153C, p.Y422*	Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Substitution - Missense, Substitution - Nonsense, Unknown	6:117288502-117288502, 6:117288562-117288563, 6:117288646-117288646, 6:117288649-117288649, 6:117288707-117288707, 6:117288731-117288731, 6:117308837-117308837, 6:117310083-117310087, 6:117310251-117310252, 6:117317189-117317190, 6:117319975-117319976, 6:117326226-117326226, 6:117326227-117326227, 6:117326295-117326299, 6:117337193-117337193, 6:117341466-117341486, 6:117341504-117341504, 6:117341537-117341537, 6:117342425-117342427, 6:117342427-117342427, 6:117353008-117353008, 6:117356905-117356928, 6:117357807-117357807, 6:117359853-117359853, 6:117359870-117359870, 6:117359956-117359957, 6:117362853-117362854, 6:117365635-117365636, 6:117365636-117365636, 6:117366221-117366221, 6:117366259-117366259, 6:117379069-117379069, 6:117387798-117387798, 6:117387831-117387831, 6:117389395-117389395, 6:117389415-117389415, 6:117389671-117389671, 6:117389843-117389843, 6:117393246-117393246, 6:117393252-117393252, 6:117393301-117393301, 6:117394187-117394187, 6:117394640-117394640, 6:117396259-117396259, 6:117396980-117396980, 6:117397004-117397004, 6:117397030-117397030, 6:117403258-117403258, 6:117416309-117416309, 6:117425565-117425565,	Info_not_available	0.50426, .52967, .53466, .54413, .55134, .55604, .55702, .55706, .57622, .58509, .58686, .58798, .60357, .60568, .61048, .62229, .6239, .62711, .62818, .63071, .63759, .64722, .64797, .66305, .66413, .67595, .67674, .67783, .6833, .6849, .68638, .68656, .69, .69797, .69816, Info_not_available	28481359