Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
NOS3	7876	COSM313294,	lung	carcinoma	p.D686Y	Substitution - Missense	7:151007220-151007220,	PATHOGENIC	0.99785	22941188
NOS3	7876	COSM40383,	central_nervous_system	glioma	p.L671L	Substitution - coding silent	7:151007175-151007175,	PATHOGENIC	0.91712	18772396
NOS3	7876	COSM32897,	large_intestine	carcinoma	p.R602Q	Substitution - Missense	7:151006479-151006479,	PATHOGENIC	0.88959	16959974
NOS3	7876	COSM32448,	large_intestine	carcinoma	p.R474C	Substitution - Missense	7:151001417-151001417,	PATHOGENIC	0.85118	16959974