Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
ANGPTL4	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
APAF1	Affinity Capture-Western	physical	9539746	NA	BioGRID
ARHGDIA	Co-purification	physical	15659383	NA	BioGRID
ATAD2	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
ATG4D	Biochemical Activity	physical	19549685	NA	BioGRID
ATP1A3	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
BAP1	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
BAX	Co-fractionation	physical	15254227	NA	BioGRID
BCAP31	Affinity Capture-Western, Biochemical Activity, Co-fractionation, Reconstituted Complex, anti bait coimmunoprecipitation, coimmunoprecipitation	physical, physical association	11917123, 15254227, 21183955, 9334338	0.40, 0.59	BioGRID, IntAct, MINT
BCL2	Affinity Capture-Western, Phenotypic Suppression, Two-hybrid, two hybrid	genetic, physical, physical association	11406564, 11832478, 16183855	0.37	BioGRID, IntAct
BCL2L1	Phenotypic Suppression, anti tag coimmunoprecipitation	genetic, physical association	11832478, 9027312	0.40	BioGRID, IntAct
BCL2L10	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
BEX1	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
BFAR	Affinity Capture-Western	physical	10716992	NA	BioGRID
BID	Biochemical Activity, Co-purification	physical	11832478, 15659383	NA	BioGRID
BIRC2	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical	12887920, 15069192, 22274400, 27810922	0.53	BioGRID, IntAct
BIRC3	Affinity Capture-Western	physical	15069192, 27810922	NA	BioGRID
BIRC6	Biochemical Activity	physical	15507451	NA	BioGRID
BLID	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
BLM	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
CARD11	Affinity Capture-Western	physical	18625728	NA	BioGRID
CASC3	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
CASP1	Biochemical Activity	physical	8962078	NA	BioGRID
CASP10	Affinity Capture-Western, Biochemical Activity, Co-purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescent resonance energy transfer	association, direct interaction, physical, physical association	11717445, 11832478, 12887920, 15280356, 15659383, 17159907, 21737330, 22864571, 8962078	0.73	BioGRID, IntAct, MINT
CASP14	Affinity Capture-Western	physical	9792675	NA	BioGRID
CASP2	Biochemical Activity	physical	11832478, 8962078	NA	BioGRID
CASP3	Biochemical Activity, protease assay	direct interaction, physical	11832478, 15254227, 18669646, 8962078	0.44	BioGRID, IntAct
CASP4	Biochemical Activity	physical	8962078	NA	BioGRID
CASP6	Biochemical Activity	physical	11832478, 12232792, 8962078	NA	BioGRID
CASP7	Biochemical Activity	physical	11832478, 8962078	NA	BioGRID
CASP8	Biochemical Activity, Co-crystal Structure, Two-hybrid, fluorescent resonance energy transfer, pull down, two hybrid, two hybrid pooling approach	direct interaction, physical, physical association	10964557, 11717445, 11832478, 16169070, 17170703, 17290218, 8681376, 8962078	0.37, 0.70	BioGRID, IntAct, MINT
CASP8AP2	Affinity Capture-Western	physical	10235259	NA	BioGRID
CASP9	Biochemical Activity, Phenotypic Suppression	genetic, physical	11832478, 8962078	NA	BioGRID
CDH13	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
CDK9	Negative Genetic	genetic	28319113	NA	BioGRID
CDKN1B	Negative Genetic	genetic	28319113	NA	BioGRID
CEBPB	Affinity Capture-Western	physical	11684016	NA	BioGRID
CFLAR	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, molecular sieving, protease assay, x-ray crystallography	association, direct interaction, physical, physical association, protein cleavage	11741985, 12215447, 12887920, 15280356, 17047155, 17159907, 19343040, 19416807, 19710364, 21737329, 21737330, 22322857, 22864571, 24438025, 26186194, 28514442, 9208847, 9228018, 9289491, 9326610	0.56, 0.62, 0.67	BioGRID, IntAct, MINT
CHD3	Two-hybrid, two hybrid pooling approach	physical, physical association	16169070	0.37	BioGRID, IntAct
CHEK1	Negative Genetic	genetic	28319113	NA	BioGRID
CHUK	Affinity Capture-Western	physical	11002417	NA	BioGRID
CLIP3	Affinity Capture-Western	physical	22297296	NA	BioGRID
CNBP	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
COPS6	Biochemical Activity	physical	17337451	NA	BioGRID
CRYAB	Affinity Capture-Western	physical	23074197	NA	BioGRID
CUL3	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, enzymatic study	physical, physical association, ubiquitination reaction	19427028, 23142077, 25551360	0.60	BioGRID, IntAct
DEDD	Affinity Capture-Western, Reconstituted Complex	physical	11965497, 12527898, 9774341	NA	BioGRID
DEDD2	Affinity Capture-Western, Reconstituted Complex	physical	11965497, 12527898	NA	BioGRID
EPSTI1	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
ERLIN2	Affinity Capture-MS	physical	21343306	NA	BioGRID
ERRFI1	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
EZR	Co-purification	physical	15659383	NA	BioGRID
FADD	Affinity Capture-Western, Co-purification, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, cosedimentation through density gradient, fluorescent resonance energy transfer, pull down, two hybrid, two hybrid array	association, colocalization, direct interaction, physical, physical association	11717445, 12107169, 12702723, 12887920, 12911633, 14612908, 15280356, 15659383, 17047155, 17159907, 18485876, 19060883, 19176810, 19524512, 20103630, 20448643, 20829884, 21458669, 21525013, 21620750, 21737329, 21737330, 21785459, 21988832, 22173242, 22179575, 22274400, 22864571, 23142077, 23955153, 23972990, 24098568, 25043603, 25911380, 25939870, 26437781, 26972597, 27321185, 27552911, 27560715, 8681376, 9228018, 9343261	0.48, 0.57, 0.98	BioGRID, IntAct, MINT
FAF1	Affinity Capture-Western	physical	21282461, 28414080	NA	BioGRID
FAS	Affinity Capture-MS, Affinity Capture-Western, Co-purification, anti bait coimmunoprecipitation, coimmunoprecipitation, cosedimentation through density gradient, imaging technique	association, colocalization, physical, physical association	11717445, 12887920, 15659383, 16498403, 17047155, 17159907, 18328427, 20956295, 21625644, 21713032, 21803845, 26186194, 26942442, 27321185, 28514442, 9208847, 9325248	0.35, 0.67, 0.91	BioGRID, IntAct, MINT
FASLG	Affinity Capture-Western, Co-purification, anti tag coimmunoprecipitation, coimmunoprecipitation, pull down	association, physical, physical association	12198154, 12753742, 12887920, 15659383, 16498403, 21803845, 24025841	0.74	BioGRID, IntAct, MINT
FIS1	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical, physical association	21183955	0.50	BioGRID, IntAct, MINT
GLCE	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
GMNN	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
GREB1	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
GZMB	Biochemical Activity	physical	17283187	NA	BioGRID
HBP1	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
HDAC7	Biochemical Activity	physical	18458084	NA	BioGRID
HECTD3	Affinity Capture-Western, Reconstituted Complex	physical	24287696	NA	BioGRID
HIP1	Affinity Capture-Western	physical	11788820	NA	BioGRID
IFT57	Affinity Capture-Western	physical	11788820	NA	BioGRID
IKBKB	Affinity Capture-Western	physical	11002417	NA	BioGRID
IL13RA2	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
IL24	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
KHDRBS1	Affinity Capture-Western	physical	21620750	NA	BioGRID
KLK5	Two-hybrid	physical	25640309	NA	BioGRID
KLK9	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
LRRK2	Affinity Capture-Western	physical	19176810	NA	BioGRID
LYPD3	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
MAP1LC3A	Affinity Capture-Western	physical	21628531	NA	BioGRID
MAP1LC3B	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT
MAP3K14	Affinity Capture-Western, pull down	physical, physical association	11002417, 12884866	0.40	BioGRID, IntAct
MAPK1	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	17290218	0.40	BioGRID, IntAct, MINT
MAPK14	Affinity Capture-Western	physical	14970175	NA	BioGRID
MAPK8	Co-purification	physical	15659383	NA	BioGRID
MLKL	Affinity Capture-MS	physical	26496610	NA	BioGRID
MSN	Co-purification	physical	15659383	NA	BioGRID
MTOR	Negative Genetic	genetic	28319113	NA	BioGRID
NLRC4	Affinity Capture-Western, anti tag coimmunoprecipitation	association, physical	12646168, 20085538, 27974463	0.35	BioGRID, IntAct
NOD1	Affinity Capture-Western	physical	10329646	NA	BioGRID
NOL3	Affinity Capture-Western, Phenotypic Suppression	genetic, physical	9560245	NA	BioGRID
NR1H4	Reconstituted Complex	physical	11733517	NA	BioGRID
NSD3	Two-hybrid	physical	25640309	NA	BioGRID
OPTN	Affinity Capture-Western	physical	27552911	NA	BioGRID
PARK7	Reconstituted Complex	physical	21785459	NA	BioGRID
PARP1	Biochemical Activity	physical	19549685	NA	BioGRID
PDIA6	Two-hybrid, two hybrid	physical, physical association	21988832	0.37	BioGRID, IntAct
PEA15	Affinity Capture-Western, Reconstituted Complex	physical	10442631, 10493725	NA	BioGRID
PLA2G4B	Biochemical Activity	physical	9875225	NA	BioGRID
PLIN4	Two-hybrid, two hybrid	physical, physical association	21988832	0.37	BioGRID, IntAct
PPP2CA	Affinity Capture-Western	physical	25551360	NA	BioGRID
PRDM14	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
PRDX6	Affinity Capture-Western, PCA, Reconstituted Complex	physical	20829884	NA	BioGRID
PRKCI	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
PRSS50	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
PSMC3IP	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
PTEN	Affinity Capture-MS, Affinity Capture-Western	physical	15717329	NA	BioGRID
QDPR	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
RALBP1	Affinity Capture-Western	physical	12887920	NA	BioGRID
RALGDS	Affinity Capture-Western	physical	21525013	NA	BioGRID
RB1	Biochemical Activity	physical	15735701	NA	BioGRID
RHOA	Co-purification	physical	15659383	NA	BioGRID
RIPK1	Affinity Capture-Western, Co-fractionation, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, pull down	association, physical, physical association	11002417, 12884866, 12887920, 17047155, 18485876, 18570872, 19060883, 19373245, 19524512, 19524513, 19773432, 20825417, 21282461, 21458669, 21525013, 21737329, 21737330, 22173242, 22179575, 22274400, 22585859, 22864571, 23955153, 23972990, 24098568, 24577083, 25911380, 25939870, 26733177, 26972597, 27552911, 27810922	0.96	BioGRID, IntAct, MINT
RIPK3	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical, physical association	19524512, 19524513, 22864571	0.56	BioGRID, IntAct
RNF34	Affinity Capture-Western, Two-hybrid	physical	15069192	NA	BioGRID
RYBP	Affinity Capture-Western	physical	27989698	NA	BioGRID
S100A14	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
SCGB2A2	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
SERPINB5	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
SERPINB9	Affinity Capture-Western	physical	17479112	NA	BioGRID
SNRPD3	Two-hybrid, two hybrid	physical, physical association	21988832	0.37	BioGRID, IntAct
SORBS1	Affinity Capture-Western	physical	12765336	NA	BioGRID
SOX2	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
SQSTM1	Affinity Capture-Western, anti bait coimmunoprecipitation, confocal microscopy	association, colocalization, physical	19427028, 21628531, 24121507	0.43	BioGRID, IntAct
ST14	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
TFCP2	Two-hybrid, two hybrid pooling approach	physical, physical association	16169070	0.37	BioGRID, IntAct
TICAM1	Affinity Capture-Western	physical	21737330	NA	BioGRID
TLR3	Affinity Capture-Western	physical	27810922	NA	BioGRID
TNF	Affinity Capture-Western	physical	24980434	NA	BioGRID
TNFAIP3	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical, physical association	19060883, 26437781	0.50	BioGRID, IntAct
TNFRSF10A	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation, confocal microscopy	association, colocalization, physical, physical association	15280356, 15388581, 17047155, 19343040, 19427028, 20103630, 21785459, 23142077, 27321185, 28514442, 9325248	0.76	BioGRID, IntAct
TNFRSF10B	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-purification, anti bait coimmunoprecipitation, confocal microscopy	association, colocalization, physical	11940602, 15388581, 15659383, 17047155, 19343040, 20103630, 23142077, 25043603, 26186194, 28514442, 28972304, 9325248	0.68	BioGRID, IntAct
TNFRSF1A	Co-purification, fluorescence microscopy	colocalization, physical	15659383, 21157428	0.27	BioGRID, IntAct, MINT
TNFSF10	Affinity Capture-Western, anti tag coimmunoprecipitation, coimmunoprecipitation, fluorescence microscopy, pull down	association, colocalization, physical	10894160, 12198154, 16801533, 19427028, 20097879, 21459798, 21525171, 21822306, 22266862, 22585859, 23142077, 23678861, 24287696, 25551360	0.92	BioGRID, IntAct, MINT
TOPORS	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	17290218	0.40	BioGRID, IntAct, MINT
TP53	Affinity Capture-Western	physical	17290218	NA	BioGRID
TRADD	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical	12887920, 17047155, 18776134, 19524513	0.64	BioGRID, IntAct
TRAF1	Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation	association, physical	11098060, 12887920	0.35	BioGRID, IntAct
TRAF2	Affinity Capture-Western, Co-localization, anti bait coimmunoprecipitation	association, physical	12887920, 17047155, 21282461, 22179575, 23142077, 28972304	0.53	BioGRID, IntAct
TRAF6	Affinity Capture-Western, FRET	physical	16436380, 16920630, 27810922	NA	BioGRID
TSC22D3	Affinity Capture-Western	physical	20671745	NA	BioGRID
UBC	Reconstituted Complex	physical	22585859	NA	BioGRID
UMPS	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
USP2	Affinity Capture-Western	physical	22179575	NA	BioGRID
VHL	Negative Genetic	genetic	28319113	NA	BioGRID
VIM	Two-hybrid, two hybrid pooling approach	physical, physical association	16169070	0.37	BioGRID, IntAct
VPS45	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT
XIAP	Affinity Capture-Western, Phenotypic Suppression	genetic, physical	11832478, 15069192, 23074197	NA	BioGRID
YBX1	Two-hybrid, two hybrid array	physical, physical association	25640309	0.37	BioGRID, IntAct, MINT