Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
AKT1	enzymatic study	cleavage reaction	17544405	0.44	IntAct, MINT
AKT2	enzymatic study	cleavage reaction	17544405	0.44	IntAct, MINT
AKT3	Co-localization, enzymatic study, proximity ligation assay	cleavage reaction, physical, physical association	17544405, 25241761	0.61	BioGRID, IntAct, MINT
APAF1	experimental interaction detection, protease accessibility laddering, protease assay	cleavage reaction, direct interaction	11550094, 21827945	0.65	IntAct, MINT
APP	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
ARHGDIB	protease assay	cleavage reaction	18723680	0.44	IntAct
ATG16L1	protease assay	protein cleavage	24553140	0.44	IntAct
BID	Biochemical Activity, protease assay	cleavage reaction, physical	11399776, 18723680	0.44	BioGRID, IntAct
BIRC2	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, enzymatic study	physical, physical association	11084335, 11106668, 17069460, 19258326, 9384571	0.40	BioGRID, IntAct
BIRC7	Affinity Capture-Western, Reconstituted Complex, enzymatic study	physical, physical association	11024045, 11084335, 23563149	0.40	BioGRID, IntAct
CALB1	isothermal titration calorimetry	direct interaction	22982862	0.44	IntAct, MINT
CASP3	Co-crystal Structure, two hybrid, x-ray crystallography	physical, physical association	11257232, 16227597	0.37, 0.40	BioGRID, IntAct, MINT
CASP6	Biochemical Activity, Co-localization, protease assay, proximity ligation assay	cleavage reaction, physical, physical association	18723680, 25241761, 8900201	0.61	BioGRID, IntAct
CASP8	Biochemical Activity, protease assay	direct interaction, physical	11832478, 15254227, 18669646, 8962078	0.44	BioGRID, IntAct
CASP9	Biochemical Activity, Co-localization, experimental interaction detection, protease assay, proximity ligation assay	association, cleavage reaction, direct interaction, physical, physical association	11230124, 11242052, 15507451, 15941357, 17437405, 18723680, 25241761	0.44, 0.67	BioGRID, IntAct, MINT
CDC42	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
CDH1	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
CDKN1A	Biochemical Activity, Co-localization, proximity ligation assay	physical, physical association	10022118, 25241761, 9660939, 9799125	0.40	BioGRID, IntAct
CRYAB	Affinity Capture-Western, Reconstituted Complex, pull down	direct interaction, physical	18669646, 23049853, 23074197	0.44	BioGRID, IntAct
CTNNB1	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
CTTN	Biochemical Activity, Co-localization, proximity ligation assay	physical, physical association	11689006, 25241761	0.40	BioGRID, IntAct
DFFA	Biochemical Activity, Co-localization, proximity ligation assay	physical, physical association	18723680, 25241761	0.40	BioGRID, IntAct
GATA1	Biochemical Activity, confocal microscopy, protease assay	colocalization, physical, protein cleavage	17167422	0.49	BioGRID, IntAct
GLRX	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
HCLS1	Biochemical Activity, Co-localization, proximity ligation assay	physical, physical association	11689006, 11988074, 25241761	0.40	BioGRID, IntAct
MAP3K14	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
MDM2	Biochemical Activity, Co-localization, protease assay, proximity ligation assay	physical, physical association, protein cleavage	21726810, 24842904, 25241761, 9278461, 9840926	0.44, 0.61	BioGRID, IntAct
MET	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
MLH1	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
NMT2	anti bait coimmunoprecipitation	physical association	16530191	0.40	IntAct, MINT
NUCB2	protease assay	cleavage reaction	18154733	0.44	IntAct, MINT
PAK2	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
PANX1	protease assay	protein cleavage	20944749	0.44	IntAct
PARP1	Biochemical Activity, protease assay	physical, protein cleavage	17167422, 18723680, 19549685, 19713971, 22451931, 7596430, 9875225	0.62	BioGRID, IntAct
PTGES3	Biochemical Activity, protease assay	cleavage reaction, physical	18723680, 22451931	0.44	BioGRID, IntAct
RAD51	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
RET	protease assay	protein cleavage	10921886	0.44	IntAct
SOCS5	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
SPP1	protease assay	protein cleavage	19706414	0.44	IntAct
STK3	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
STK4	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
TRAF1	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
TXN	anti bait coimmunoprecipitation, fluorescence polarization spectroscopy, isothermal titration calorimetry, protease assay, pull down	direct interaction, physical association, protein cleavage	17606900	0.67	IntAct
WNK3 	anti bait coimmunoprecipitation, antibody array	physical association	16501604	0.52	IntAct
XIAP	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Co-localization, Reconstituted Complex, anti tag coimmunoprecipitation, proximity ligation assay, pull down, x-ray crystallography	direct interaction, physical, physical association	11257230, 11257232, 11359776, 11447297, 11927604, 12624662, 15200957, 15507451, 15650747, 16543147, 16869888, 17069460, 17291493, 18521960, 18723680, 19273858, 19698783, 22072751, 22815893, 23074197, 23979166, 25241761, 26186194, 28514442, 9230442, 9384571, 9525868	0.79	BioGRID, IntAct, MINT
YWHAE	two hybrid	physical association	12657644	0.37	IntAct, MINT
YWHAG	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct