Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
ALK	427	COSM98478,	autonomic_ganglia	neuroblastoma	p.T1151M	Substitution - Missense	2:29222407-29222407,	PATHOGENIC	0.99782	28481359
ALK	427	COSM98478,	autonomic_ganglia	neuroblastoma	p.T1151M	Substitution - Missense	2:29222407-29222407,	PATHOGENIC	0.99782	21632861
ALK	427	COSM98478,	autonomic_ganglia	neuroblastoma	p.T1151M	Substitution - Missense	2:29222407-29222407,	PATHOGENIC	0.99782	25517749
ALK	427	COSM98478,	autonomic_ganglia	neuroblastoma	p.T1151M	Substitution - Missense	2:29222407-29222407,	PATHOGENIC	0.99782	21632861
ALK	427	COSM97185,	lung	carcinoma	p.L1152R	Substitution - Missense	2:29222404-29222404,	PATHOGENIC	0.99776	21791641
ALK	427	COSM6915427,	NS	carcinoma	p.P1213H	Substitution - Missense	2:29220713-29220713,	PATHOGENIC	0.99734	28481359
ALK	427	COSM6978018,	skin	malignant_melanoma	p.P1578S	Substitution - Missense	2:29193355-29193355,	PATHOGENIC	0.99731	28481359
ALK	427	COSM6938297,	lung	carcinoma	p.G932A	Substitution - Missense	2:29228904-29228904,	PATHOGENIC	0.99725	28481359
ALK	427	COSM6958945,	lung	carcinoma	p.G931V	Substitution - Missense	2:29228907-29228907,	PATHOGENIC	0.99718	28481359
ALK	427	COSM6925446,	prostate	carcinoma	p.G925*	Substitution - Nonsense	2:29228926-29228926,	PATHOGENIC	0.99707	28481359
ALK	427	COSM6971123,	pancreas	carcinoma	p.I1116T	Substitution - Missense	2:29223354-29223354,	PATHOGENIC	0.99704	28481359
ALK	427	COSM2941488,	oesophagus	carcinoma	p.G925R	Substitution - Missense	2:29228926-29228926,	PATHOGENIC	0.99691	24686850
ALK	427	COSM6927911,	breast	carcinoma	p.Q1482K	Substitution - Missense	2:29193643-29193643,	PATHOGENIC	0.99691	28481359
ALK	427	COSM5607780,	skin	malignant_melanoma	p.G923E	Substitution - Missense	2:29228931-29228931,	PATHOGENIC	0.99686	26343386
ALK	427	COSM6932900,	skin	carcinoma	p.G920D	Substitution - Missense	2:29228940-29228940,	PATHOGENIC	0.99686	28481359
ALK	427	COSM6904749,	thyroid	carcinoma	p.D1203H	Substitution - Missense	2:29220744-29220744,	PATHOGENIC	0.99605	28351340
ALK	427	COSM327056,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R1209Q	Substitution - Missense	2:29220725-29220725,	PATHOGENIC	0.99544	22675565
ALK	427	COSM327056,	breast	carcinoma	p.R1209Q	Substitution - Missense	2:29220725-29220725,	PATHOGENIC	0.99544	27284958
ALK	427	COSM327056,	skin	malignant_melanoma	p.R1209Q	Substitution - Missense	2:29220725-29220725,	PATHOGENIC	0.99544	28481359
ALK	427	COSM6191344,	lung	carcinoma	p.D1203N	Substitution - Missense	2:29220744-29220744,	PATHOGENIC	0.99544	28434515
ALK	427	COSM6911337,	skin	carcinoma	p.V972M	Substitution - Missense	2:29227574-29227574,	PATHOGENIC	0.99536	28481359
ALK	427	COSM6963193,	skin	malignant_melanoma	p.S1495F	Substitution - Missense	2:29193603-29193603,	PATHOGENIC	0.99389	28481359
ALK	427	COSM6950653,	lung	carcinoma	p.P1418H	Substitution - Missense	2:29193834-29193834,	PATHOGENIC	0.99378	28481359
ALK	427	COSM4440758,	lung	carcinoma	p.I1171S	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.9933	25393796
ALK	427	COSM98477,	autonomic_ganglia	neuroblastoma	p.I1170S	Substitution - Missense	2:29222350-29222350,	PATHOGENIC	0.9933	21632861
ALK	427	COSM98477,	autonomic_ganglia	neuroblastoma	p.I1170S	Substitution - Missense	2:29222350-29222350,	PATHOGENIC	0.9933	25517749
ALK	427	COSM28497,	autonomic_ganglia	neuroblastoma	p.M1166R	Substitution - Missense	2:29222362-29222362,	PATHOGENIC	0.9933	25517749
ALK	427	COSM28497,	autonomic_ganglia	neuroblastoma	p.M1166R	Substitution - Missense	2:29222362-29222362,	PATHOGENIC	0.9933	18724359
ALK	427	COSM2941511,	endometrium	carcinoma	p.S737L	Substitution - Missense	2:29239825-29239825,	PATHOGENIC	0.99323	25233892
ALK	427	COSM2941511,	urinary_tract	carcinoma	p.S737L	Substitution - Missense	2:29239825-29239825,	PATHOGENIC	0.99323	28481359
ALK	427	COSM28498,	autonomic_ganglia	neuroblastoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	25517749
ALK	427	COSM28498,	lung	carcinoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	25393798
ALK	427	COSM4989835,	autonomic_ganglia	neuroblastoma	p.I1170N	Substitution - Missense	2:29222350-29222350,	PATHOGENIC	0.99295	25517749
ALK	427	COSM28498,	lung	carcinoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	25736571
ALK	427	COSM28498,	lung	carcinoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	27565911
ALK	427	COSM28498,	lung	carcinoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	27565911
ALK	427	COSM28498,	autonomic_ganglia	neuroblastoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	18724359
ALK	427	COSM28498,	autonomic_ganglia	neuroblastoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	18724359
ALK	427	COSM28498,	lung	carcinoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	25393796
ALK	427	COSM28498,	autonomic_ganglia	neuroblastoma	p.I1171N	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99295	25517749
ALK	427	COSM6964854,	lung	carcinoma	p.M1166T	Substitution - Missense	2:29222362-29222362,	PATHOGENIC	0.99287	28481359
ALK	427	COSM4381100,	lung	carcinoma	p.I1171T	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99287	25393798
ALK	427	COSM98476,	autonomic_ganglia	neuroblastoma	p.I1170T	Substitution - Missense	2:29222350-29222350,	PATHOGENIC	0.99287	21632861
ALK	427	COSM4381100,	lung	carcinoma	p.I1171T	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99287	25228534
ALK	427	COSM4381100,	lung	carcinoma	p.I1171T	Substitution - Missense	2:29222347-29222347,	PATHOGENIC	0.99287	25228534
ALK	427	COSM6930798,	lung	carcinoma	p.Q777R	Substitution - Missense	2:29239705-29239705,	PATHOGENIC	0.99262	28481359
ALK	427	COSM98475,	autonomic_ganglia	neuroblastoma	p.G1128A	Substitution - Missense	2:29222584-29222584,	PATHOGENIC	0.99192	21632861
ALK	427	COSM1326219,	urinary_tract	carcinoma	p.G1585S	Substitution - Missense	2:29193334-29193334,	PATHOGENIC	0.99183	28481359
ALK	427	COSM6961636,	large_intestine	carcinoma	p.?	Unknown	2:29227673-29227673,	PATHOGENIC	0.99149	28481359
ALK	427	COSM6981088,	lung	carcinoma	p.S1020C	Substitution - Missense	2:29226930-29226930,	PATHOGENIC	0.99146	28481359
ALK	427	COSM6968291,	lung	carcinoma	p.D1160H	Substitution - Missense	2:29222381-29222381,	PATHOGENIC	0.99145	28481359
ALK	427	COSM6968260,	lung	carcinoma	p.D1163H	Substitution - Missense	2:29222372-29222372,	PATHOGENIC	0.99145	28481359
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	22142829
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	21632861
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	18923525
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	28481359
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	22142829
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	18923525
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	22085494
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	27009842
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	18724359
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28500,	autonomic_ganglia	neuroblastoma	p.F1245C	Substitution - Missense	2:29213993-29213993,	PATHOGENIC	0.99132	25517749
ALK	427	COSM28499,	autonomic_ganglia	neuroblastoma	p.F1245V	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99132	18724359
ALK	427	COSM6924610,	lung	carcinoma	p.A704D	Substitution - Missense	2:29251198-29251198,	PATHOGENIC	0.99107	28481359
ALK	427	COSM6984806,	large_intestine	carcinoma	p.S895Y	Substitution - Missense	2:29229015-29229015,	PATHOGENIC	0.99104	28481359
ALK	427	COSM5991567,	skin	adnexal_tumour	p.P1191L	Substitution - Missense	2:29220779-29220779,	PATHOGENIC	0.99072	27311873
ALK	427	COSM5991565,	skin	adnexal_tumour	p.P1191S	Substitution - Missense	2:29220780-29220780,	PATHOGENIC	0.99072	27311873
ALK	427	COSM28492,	autonomic_ganglia	neuroblastoma	p.F1245I	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99067	28481359
ALK	427	COSM28492,	autonomic_ganglia	neuroblastoma	p.F1245I	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99067	25517749
ALK	427	COSM28492,	autonomic_ganglia	neuroblastoma	p.F1245I	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99067	23084186
ALK	427	COSM28492,	autonomic_ganglia	neuroblastoma	p.F1245I	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99067	18990089
ALK	427	COSM28492,	autonomic_ganglia	neuroblastoma	p.F1245I	Substitution - Missense	2:29213994-29213994,	PATHOGENIC	0.99067	25517749
ALK	427	COSM144251,	lung	carcinoma	p.S1206Y	Substitution - Missense	2:29220734-29220734,	PATHOGENIC	0.99046	22277784
ALK	427	COSM107739,	upper_aerodigestive_tract	carcinoma	p.R1212H	Substitution - Missense	2:29220716-29220716,	PATHOGENIC	0.99037	28581676
ALK	427	COSM20632,	ovary	carcinoma	p.A877S	Substitution - Missense	2:29232307-29232307,	PATHOGENIC	0.99016	Info_not_available
ALK	427	COSM20632,	ovary	carcinoma	p.A877S	Substitution - Missense	2:29232307-29232307,	PATHOGENIC	0.99016	Info_not_available
ALK	427	COSM6909462,	urinary_tract	carcinoma	p.G692R	Substitution - Missense	2:29251235-29251235,	PATHOGENIC	0.99015	28481359
ALK	427	COSM6908629,	breast	carcinoma	p.G940D	Substitution - Missense	2:29227669-29227669,	PATHOGENIC	0.98999	28481359
ALK	427	COSM28054,	autonomic_ganglia	neuroblastoma	p.F1174V	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98991	25517749
ALK	427	COSM28054,	autonomic_ganglia	neuroblastoma	p.F1174V	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98991	18923523
ALK	427	COSM28054,	autonomic_ganglia	neuroblastoma	p.F1174V	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98991	18923524
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	25517749
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	25517749
ALK	427	COSM28054,	lung	carcinoma	p.F1174V	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98991	24736079
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	25517749
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	21940108
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	23202128
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	22142829
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	21940108
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	18923524
ALK	427	COSM28054,	autonomic_ganglia	neuroblastoma	p.F1174V	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98991	25517749
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	18923523
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	25517749
ALK	427	COSM28054,	autonomic_ganglia	neuroblastoma	p.F1174V	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98991	23084186
ALK	427	COSM28059,	autonomic_ganglia	neuroblastoma	p.F1174C	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.98991	21632861
ALK	427	COSM6914470,	large_intestine	carcinoma	p.G689W	Substitution - Missense	2:29251244-29251244,	PATHOGENIC	0.98967	28481359
ALK	427	COSM6914470,	lung	carcinoma	p.G689W	Substitution - Missense	2:29251244-29251244,	PATHOGENIC	0.98967	28481359
ALK	427	COSM6914470,	large_intestine	carcinoma	p.G689W	Substitution - Missense	2:29251244-29251244,	PATHOGENIC	0.98967	28481359
ALK	427	COSM5045108,	lung	carcinoma	p.G1123S	Substitution - Missense	2:29222600-29222600,	PATHOGENIC	0.98958	26134233
ALK	427	COSM6968551,	large_intestine	carcinoma	p.G740R	Substitution - Missense	2:29239817-29239817,	PATHOGENIC	0.98945	28481359
ALK	427	COSM6854511,	large_intestine	other	p.A1047T	Substitution - Missense	2:29225494-29225494,	PATHOGENIC	0.98933	28524162
ALK	427	COSM4991725,	skin	carcinoma	p.E1568K	Substitution - Missense	2:29193385-29193385,	PATHOGENIC	0.98927	25589618
ALK	427	COSM6909200,	salivary_gland	carcinoma	p.S1206F	Substitution - Missense	2:29220734-29220734,	PATHOGENIC	0.98911	28481359
ALK	427	COSM28491,	autonomic_ganglia	neuroblastoma	p.F1174I	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98903	18990089
ALK	427	COSM28491,	autonomic_ganglia	neuroblastoma	p.F1174I	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98903	18724359
ALK	427	COSM28491,	autonomic_ganglia	neuroblastoma	p.F1174I	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98903	25517749
ALK	427	COSM1169447,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L1196Q	Substitution - Missense	2:29220764-29220764,	PATHOGENIC	0.98903	23239810
ALK	427	COSM28491,	autonomic_ganglia	neuroblastoma	p.F1174I	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.98903	25517749
ALK	427	COSM53063,	autonomic_ganglia	neuroblastoma	p.F1174S	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.989	23084186
ALK	427	COSM28057,	autonomic_ganglia	ganglioneuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	27009842
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	25653133
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	27009842
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	22142829
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	25517749
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	18923523
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	22142829
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	18923523
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	23084186
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	25517749
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	25653133
ALK	427	COSM53063,	autonomic_ganglia	neuroblastoma	p.F1174S	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.989	21059859
ALK	427	COSM53063,	autonomic_ganglia	neuroblastoma	p.F1174S	Substitution - Missense	2:29220830-29220830,	PATHOGENIC	0.989	25517749
ALK	427	COSM28057,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220831-29220831,	PATHOGENIC	0.989	22142829
ALK	427	COSM99136,	lung	carcinoma	p.C1156Y	Substitution - Missense	2:29222392-29222392,	PATHOGENIC	0.98875	20979473
ALK	427	COSM99136,	lung	carcinoma	p.C1156Y	Substitution - Missense	2:29222392-29222392,	PATHOGENIC	0.98875	23434628
ALK	427	COSM99136,	lung	carcinoma	p.C1156Y	Substitution - Missense	2:29222392-29222392,	PATHOGENIC	0.98875	27045755
ALK	427	COSM5607762,	skin	malignant_melanoma	p.E1167K	Substitution - Missense	2:29222360-29222360,	PATHOGENIC	0.98875	26343386
ALK	427	COSM6964300,	lung	carcinoma	p.H258Y	Substitution - Missense	2:29717593-29717593,	PATHOGENIC	0.98863	28481359
ALK	427	COSM6919849,	breast	carcinoma	p.E1154K	Substitution - Missense	2:29222399-29222399,	PATHOGENIC	0.98854	28481359
ALK	427	COSM6909749,	urinary_tract	carcinoma	p.E780K	Substitution - Missense	2:29239697-29239697,	PATHOGENIC	0.98831	28481359
ALK	427	COSM6936597,	skin	malignant_melanoma	p.G878S	Substitution - Missense	2:29232304-29232304,	PATHOGENIC	0.98823	28481359
ALK	427	COSM50288,	large_intestine	carcinoma	p.A1168P	Substitution - Missense	2:29222357-29222357,	PATHOGENIC	0.98808	17932254
ALK	427	COSM6948461,	lung	carcinoma	p.G977R	Substitution - Missense	2:29227060-29227060,	PATHOGENIC	0.98793	28481359
ALK	427	COSM5607781,	skin	malignant_melanoma	p.G977E	Substitution - Missense	2:29227059-29227059,	PATHOGENIC	0.98793	26343386
ALK	427	COSM4381101,	lung	carcinoma	p.V1180L	Substitution - Missense	2:29220813-29220813,	PATHOGENIC	0.98767	25228534
ALK	427	COSM6972326,	lung	carcinoma	p.A690T	Substitution - Missense	2:29251241-29251241,	PATHOGENIC	0.98766	28481359
ALK	427	COSM6927161,	lung	carcinoma	p.?	Unknown	2:29232449-29232449,	PATHOGENIC	0.98757	28481359
ALK	427	COSM6938859,	endometrium	carcinoma	p.S1172G	Substitution - Missense	2:29222345-29222345,	PATHOGENIC	0.98756	28481359
ALK	427	COSM442800,	large_intestine	carcinoma	p.G843R	Substitution - Missense	2:29232409-29232409,	PATHOGENIC	0.98754	28481359
ALK	427	COSM5607758,	skin	malignant_melanoma	p.G1184V	Substitution - Missense	2:29220800-29220800,	PATHOGENIC	0.98686	26343386
ALK	427	COSM6941952,	large_intestine	carcinoma	p.T697A	Substitution - Missense	2:29251220-29251220,	PATHOGENIC	0.98675	28481359
ALK	427	COSM6921422,	breast	carcinoma	p.N1497K	Substitution - Missense	2:29193596-29193596,	PATHOGENIC	0.98636	28481359
ALK	427	COSM6979632,	NS	malignant_melanoma	p.G902*	Substitution - Nonsense	2:29228995-29228995,	PATHOGENIC	0.98581	28481359
ALK	427	COSM143842,	soft_tissue	rhabdomyosarcoma	p.D1225N	Substitution - Missense	2:29214054-29214054,	PATHOGENIC	0.9855	22184391
ALK	427	COSM1690369,	skin	adnexal_tumour	p.E1242K	Substitution - Missense	2:29214003-29214003,	PATHOGENIC	0.9855	28481359
ALK	427	COSM28617,	autonomic_ganglia	neuroblastoma	p.A1234T	Substitution - Missense	2:29214027-29214027,	PATHOGENIC	0.9855	18923525
ALK	427	COSM6949223,	breast	carcinoma	p.R1214H	Substitution - Missense	2:29220710-29220710,	PATHOGENIC	0.9854	28481359
ALK	427	COSM6949223,	large_intestine	carcinoma	p.R1214H	Substitution - Missense	2:29220710-29220710,	PATHOGENIC	0.9854	28481359
ALK	427	COSM6196757,	large_intestine	carcinoma	p.I1268N	Substitution - Missense	2:29209819-29209819,	PATHOGENIC	0.98523	27756406
ALK	427	COSM6196757,	large_intestine	carcinoma	p.I1268N	Substitution - Missense	2:29209819-29209819,	PATHOGENIC	0.98523	27756406
ALK	427	COSM1651691,	soft_tissue	rhabdomyosarcoma	p.I1277T	Substitution - Missense	2:29209792-29209792,	PATHOGENIC	0.98504	23307059
ALK	427	COSM28061,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	18923524
ALK	427	COSM28061,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	21632861
ALK	427	COSM28061,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	25071110
ALK	427	COSM28061,	lung	carcinoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	28434515
ALK	427	COSM28061,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	28481359
ALK	427	COSM28061,	lung	carcinoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	28481359
ALK	427	COSM28061,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	21632861
ALK	427	COSM28061,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	25517749
ALK	427	COSM28061,	lung	carcinoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	28434515
ALK	427	COSM28061,	soft_tissue	inflammatory_myofibroblastic_tumour	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.9847	21030459
ALK	427	COSM6963686,	large_intestine	carcinoma	p.D1232G	Substitution - Missense	2:29214032-29214032,	PATHOGENIC	0.984	28481359
ALK	427	COSM6939222,	endometrium	carcinoma	p.R259H	Substitution - Missense	2:29717589-29717589,	PATHOGENIC	0.98381	28481359
ALK	427	COSM6939222,	large_intestine	carcinoma	p.R259H	Substitution - Missense	2:29717589-29717589,	PATHOGENIC	0.98381	28481359
ALK	427	COSM6954752,	soft_tissue	gastrointestinal_stromal_tumour	p.G1137R	Substitution - Missense	2:29222558-29222558,	PATHOGENIC	0.98329	28481359
ALK	427	COSM97029,	thyroid	carcinoma	p.G1201E	Substitution - Missense	2:29220749-29220749,	PATHOGENIC	0.98319	21596819
ALK	427	COSM1570337,	lung	carcinoma	p.G1184E	Substitution - Missense	2:29220800-29220800,	PATHOGENIC	0.98319	27056568
ALK	427	COSM6927488,	thyroid	carcinoma	p.G1202E	Substitution - Missense	2:29220746-29220746,	PATHOGENIC	0.98319	28481359
ALK	427	COSM6226578,	large_intestine	carcinoma	p.R1181H	Substitution - Missense	2:29220809-29220809,	PATHOGENIC	0.98319	28481359
ALK	427	COSM144250,	lung	carcinoma	p.G1202R	Substitution - Missense	2:29220747-29220747,	PATHOGENIC	0.98319	27130468
ALK	427	COSM1570337,	thyroid	carcinoma	p.G1184E	Substitution - Missense	2:29220800-29220800,	PATHOGENIC	0.98319	26971368
ALK	427	COSM144250,	lung	carcinoma	p.G1202R	Substitution - Missense	2:29220747-29220747,	PATHOGENIC	0.98319	24736079
ALK	427	COSM144250,	lung	carcinoma	p.G1202R	Substitution - Missense	2:29220747-29220747,	PATHOGENIC	0.98319	22277784
ALK	427	COSM5030957,	skin	adnexal_tumour	p.M1199I	Substitution - Missense	2:29220754-29220754,	PATHOGENIC	0.98319	27311873
ALK	427	COSM5030957,	salivary_gland	carcinoma	p.M1199I	Substitution - Missense	2:29220754-29220754,	PATHOGENIC	0.98319	26053092
ALK	427	COSM1570337,	thymus	thymic_carcinoma	p.G1184E	Substitution - Missense	2:29220800-29220800,	PATHOGENIC	0.98319	23639785
ALK	427	COSM1570337,	thyroid	carcinoma	p.G1184E	Substitution - Missense	2:29220800-29220800,	PATHOGENIC	0.98319	26971368
ALK	427	COSM144250,	skin	malignant_melanoma	p.G1202R	Substitution - Missense	2:29220747-29220747,	PATHOGENIC	0.98319	28481359
ALK	427	COSM6958531,	skin	malignant_melanoma	p.G1201R	Substitution - Missense	2:29220750-29220750,	PATHOGENIC	0.98319	28481359
ALK	427	COSM6953492,	skin	carcinoma	p.W726*	Substitution - Nonsense	2:29251131-29251131,	PATHOGENIC	0.98302	28481359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	23202128
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923525
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923525
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923523
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	22142829
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18724359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	23202128
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923524
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923525
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923525
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	22142829
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18724359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923525
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923524
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18990089
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	21632861
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	23084186
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923525
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18724359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923524
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	22142829
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	27009842
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18990089
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	27009842
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	27009842
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923523
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18724359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18724359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	21632861
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18724359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	22142829
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	23202128
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18990089
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	prostate	carcinoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	20579941
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	23084186
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923524
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	22142829
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	22142829
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923523
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923524
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923523
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	28481359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	28481359
ALK	427	COSM28055,	salivary_gland	carcinoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	26053092
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	27888620
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923524
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25071110
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923523
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923525
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18724359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18724359
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	26822237
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923524
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25653133
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	23202128
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	21632861
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	18923524
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	22142829
ALK	427	COSM28055,	autonomic_ganglia	neuroblastoma	p.F1174L	Substitution - Missense	2:29220829-29220829,	PATHOGENIC	0.98285	25517749
ALK	427	COSM1169707,	lung	carcinoma	p.G1269A	Substitution - Missense	2:29209816-29209816,	PATHOGENIC	0.98268	28434515
ALK	427	COSM1169707,	lung	carcinoma	p.G1269A	Substitution - Missense	2:29209816-29209816,	PATHOGENIC	0.98268	23344087
ALK	427	COSM1169707,	lung	carcinoma	p.G1269A	Substitution - Missense	2:29209816-29209816,	PATHOGENIC	0.98268	23344087
ALK	427	COSM1169707,	lung	carcinoma	p.G1269A	Substitution - Missense	2:29209816-29209816,	PATHOGENIC	0.98268	23434628
ALK	427	COSM1169707,	lung	carcinoma	p.G1269A	Substitution - Missense	2:29209816-29209816,	PATHOGENIC	0.98268	23344087
ALK	427	COSM1169707,	lung	carcinoma	p.G1269A	Substitution - Missense	2:29209816-29209816,	PATHOGENIC	0.98268	27045755
ALK	427	COSM1169707,	lung	carcinoma	p.G1269A	Substitution - Missense	2:29209816-29209816,	PATHOGENIC	0.98268	28434515
ALK	427	COSM97028,	thyroid	carcinoma	p.L1198F	Substitution - Missense	2:29220759-29220759,	PATHOGENIC	0.98239	21596819
ALK	427	COSM6932432,	urinary_tract	carcinoma	p.G902E	Substitution - Missense	2:29228994-29228994,	PATHOGENIC	0.98216	28481359
ALK	427	COSM6954025,	skin	malignant_melanoma	p.W883*	Substitution - Nonsense	2:29229051-29229051,	PATHOGENIC	0.98216	28481359
ALK	427	COSM6948510,	eye	malignant_melanoma	p.F1052I	Substitution - Missense	2:29225479-29225479,	PATHOGENIC	0.9819	28481359
ALK	427	COSM7325416,	biliary_tract	carcinoma	p.M1199V	Substitution - Missense	2:29220756-29220756,	PATHOGENIC	0.98171	29360550
ALK	427	COSM28060,	autonomic_ganglia	neuroblastoma	p.R1275L	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.98162	25517749
ALK	427	COSM28060,	autonomic_ganglia	neuroblastoma	p.R1275L	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.98162	25517749
ALK	427	COSM28060,	autonomic_ganglia	neuroblastoma	p.R1275L	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.98162	18923523
ALK	427	COSM28060,	autonomic_ganglia	neuroblastoma	p.R1275L	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.98162	27888620
ALK	427	COSM28060,	autonomic_ganglia	neuroblastoma	p.R1275L	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.98162	25517749
ALK	427	COSM6918973,	adrenal_gland	adrenal_cortical_carcinoma	p.Q1146K	Substitution - Missense	2:29222531-29222531,	PATHOGENIC	0.9807	28481359
ALK	427	COSM4991731,	skin	carcinoma	p.N709S	Substitution - Missense	2:29251183-29251183,	PATHOGENIC	0.98043	25589618
ALK	427	COSM6973373,	pancreas	carcinoma	p.G1100C	Substitution - Missense	2:29223403-29223403,	PATHOGENIC	0.97993	28481359
ALK	427	COSM99137,	lung	carcinoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	23344087
ALK	427	COSM99137,	lung	carcinoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	20979473
ALK	427	COSM99137,	lung	carcinoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	22277784
ALK	427	COSM99137,	autonomic_ganglia	neuroblastoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	25071110
ALK	427	COSM99137,	lung	carcinoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	23434628
ALK	427	COSM99137,	lung	carcinoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	28434515
ALK	427	COSM99137,	autonomic_ganglia	neuroblastoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	25517749
ALK	427	COSM99137,	lung	carcinoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	23344087
ALK	427	COSM99137,	autonomic_ganglia	neuroblastoma	p.L1196M	Substitution - Missense	2:29220765-29220765,	PATHOGENIC	0.97942	25071110
ALK	427	COSM28058,	autonomic_ganglia	neuroblastoma	p.Y1278S	Substitution - Missense	2:29209789-29209789,	PATHOGENIC	0.97924	25517749
ALK	427	COSM28058,	autonomic_ganglia	neuroblastoma	p.Y1278S	Substitution - Missense	2:29209789-29209789,	PATHOGENIC	0.97924	25071110
ALK	427	COSM28058,	autonomic_ganglia	neuroblastoma	p.Y1278S	Substitution - Missense	2:29209789-29209789,	PATHOGENIC	0.97924	25071110
ALK	427	COSM317003,	oesophagus	carcinoma	p.A1200V	Substitution - Missense	2:29220752-29220752,	PATHOGENIC	0.97924	28481359
ALK	427	COSM28058,	autonomic_ganglia	neuroblastoma	p.Y1278S	Substitution - Missense	2:29209789-29209789,	PATHOGENIC	0.97924	18923523
ALK	427	COSM5991564,	skin	adnexal_tumour	p.S1189F	Substitution - Missense	2:29220785-29220785,	PATHOGENIC	0.97924	27311873
ALK	427	COSM317003,	autonomic_ganglia	neuroblastoma	p.A1200V	Substitution - Missense	2:29220752-29220752,	PATHOGENIC	0.97924	25517749
ALK	427	COSM28058,	autonomic_ganglia	neuroblastoma	p.Y1278S	Substitution - Missense	2:29209789-29209789,	PATHOGENIC	0.97924	25071110
ALK	427	COSM6926085,	lung	carcinoma	p.P1215T	Substitution - Missense	2:29220708-29220708,	PATHOGENIC	0.97876	28481359
ALK	427	COSM6965036,	soft_tissue	angiosarcoma	p.R1212C	Substitution - Missense	2:29220717-29220717,	PATHOGENIC	0.97847	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23084186
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923524
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923524
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18724359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18990089
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22142829
ALK	427	COSM28056,	breast	carcinoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23739063
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23202128
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22085494
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23202128
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923524
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23202128
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18724359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22142829
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23084186
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22142829
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923524
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923523
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23202128
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM6191472,	lung	carcinoma	p.A1274T	Substitution - Missense	2:29209802-29209802,	PATHOGENIC	0.97717	26645239
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22142829
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21632861
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923524
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923523
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923523
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22142829
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25188507
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21632861
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21632861
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25071110
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22085494
ALK	427	COSM28056,	thymus	thymic_carcinoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	27844328
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18724359
ALK	427	COSM28056,	prostate	carcinoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23202128
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923524
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23084186
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23084186
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18990089
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18990089
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923524
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25071110
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21632861
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18724359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25071110
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923523
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21632861
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25071110
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23084186
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22142829
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18724359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18724359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21632861
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923523
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923524
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23202128
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21632861
ALK	427	COSM28056,	large_intestine	carcinoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23202128
ALK	427	COSM6945448,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.M1273I	Substitution - Missense	2:29209803-29209803,	PATHOGENIC	0.97717	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18923525
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	28481359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21632861
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18990089
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	21940108
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18724359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	22142829
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25071110
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	18724359
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25653133
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	23084186
ALK	427	COSM28056,	autonomic_ganglia	neuroblastoma	p.R1275Q	Substitution - Missense	2:29209798-29209798,	PATHOGENIC	0.97717	25188507
ALK	427	COSM6968801,	lung	carcinoma	p.G718A	Substitution - Missense	2:29251156-29251156,	PATHOGENIC	0.97626	28481359
ALK	427	COSM6851643,	breast	carcinoma	p.A900T	Substitution - Missense	2:29229001-29229001,	PATHOGENIC	0.97622	25591616
ALK	427	COSM6196758,	large_intestine	carcinoma	p.G1261D	Substitution - Missense	2:29209840-29209840,	PATHOGENIC	0.97589	27756406
ALK	427	COSM6191473,	large_intestine	carcinoma	p.C1259Y	Substitution - Missense	2:29209846-29209846,	PATHOGENIC	0.97589	27756406
ALK	427	COSM6196759,	large_intestine	carcinoma	p.D1249N	Substitution - Missense	2:29209877-29209877,	PATHOGENIC	0.97589	27756406
ALK	427	COSM6196759,	skin	malignant_melanoma	p.D1249N	Substitution - Missense	2:29209877-29209877,	PATHOGENIC	0.97589	28481359
ALK	427	COSM6191473,	lung	carcinoma	p.C1259Y	Substitution - Missense	2:29209846-29209846,	PATHOGENIC	0.97589	26645239
ALK	427	COSM4989836,	autonomic_ganglia	neuroblastoma	p.D1270G	Substitution - Missense	2:29209813-29209813,	PATHOGENIC	0.97513	25517749
ALK	427	COSM6970412,	skin	malignant_melanoma	p.P729L	Substitution - Missense	2:29251123-29251123,	PATHOGENIC	0.97484	28481359
ALK	427	COSM5431472,	NS	malignant_melanoma	p.P729S	Substitution - Missense	2:29251124-29251124,	PATHOGENIC	0.97416	28481359
ALK	427	COSM914372,	autonomic_ganglia	neuroblastoma	p.D1249G	Substitution - Missense	2:29209876-29209876,	PATHOGENIC	0.97383	23084186
ALK	427	COSM6981179,	skin	malignant_melanoma	p.K852E	Substitution - Missense	2:29232382-29232382,	PATHOGENIC	0.97311	28481359
ALK	427	COSM138291,	lung	carcinoma	p.R1214C	Substitution - Missense	2:29220711-29220711,	PATHOGENIC	0.97307	28481359
ALK	427	COSM6950712,	skin	malignant_melanoma	p.P254S	Substitution - Missense	2:29717605-29717605,	PATHOGENIC	0.97276	28481359
ALK	427	COSM4991728,	skin	carcinoma	p.P907L	Substitution - Missense	2:29228979-29228979,	PATHOGENIC	0.97075	25589618
ALK	427	COSM5417523,	endometrium	carcinoma	p.P1292L	Substitution - Missense	2:29207234-29207234,	PATHOGENIC	0.97074	25233892
ALK	427	COSM6914238,	skin	carcinoma	p.A1280V	Substitution - Missense	2:29207270-29207270,	PATHOGENIC	0.97071	28481359
ALK	427	COSM6914238,	lung	carcinoma	p.A1280V	Substitution - Missense	2:29207270-29207270,	PATHOGENIC	0.97071	28481359
ALK	427	COSM4661136,	large_intestine	carcinoma	p.R1120W	Substitution - Missense	2:29223343-29223343,	PATHOGENIC	0.97069	28481359
ALK	427	COSM4991727,	skin	carcinoma	p.P907P	Substitution - coding silent	2:29228978-29228978,	PATHOGENIC	0.97042	25589618
ALK	427	COSM6972481,	lung	carcinoma	p.P1297T	Substitution - Missense	2:29207220-29207220,	PATHOGENIC	0.9699	28481359
ALK	427	COSM6921989,	breast	carcinoma	p.E1110D	Substitution - Missense	2:29223371-29223371,	PATHOGENIC	0.96976	28481359
ALK	427	COSM6950361,	lung	carcinoma	p.T246S	Substitution - Missense	2:29717628-29717628,	PATHOGENIC	0.96842	28481359
ALK	427	COSM6967642,	skin	carcinoma	p.G382R	Substitution - Missense	2:29531925-29531925,	PATHOGENIC	0.96703	28481359
ALK	427	COSM6936706,	stomach	carcinoma	p.P475S	Substitution - Missense	2:29320874-29320874,	PATHOGENIC	0.96642	28481359
ALK	427	COSM6936706,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P475S	Substitution - Missense	2:29320874-29320874,	PATHOGENIC	0.96642	28481359
ALK	427	COSM6936706,	endometrium	carcinoma	p.P475S	Substitution - Missense	2:29320874-29320874,	PATHOGENIC	0.96642	28481359
ALK	427	COSM50296,	large_intestine	carcinoma	p.V757M	Substitution - Missense	2:29239766-29239766,	PATHOGENIC	0.96586	17932254
ALK	427	COSM6961493,	kidney	carcinoma	p.V712M	Substitution - Missense	2:29251175-29251175,	PATHOGENIC	0.96473	28481359
ALK	427	COSM4989837,	autonomic_ganglia	neuroblastoma	p.G1286R	Substitution - Missense	2:29207253-29207253,	PATHOGENIC	0.96438	25517749
ALK	427	COSM6948366,	lung	carcinoma	p.M830I	Substitution - Missense	2:29232446-29232446,	PATHOGENIC	0.96311	28481359
ALK	427	COSM48228,	lung	carcinoma	p.V1135E	Substitution - Missense	2:29222563-29222563,	PATHOGENIC	0.96288	18948947
ALK	427	COSM327053,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R1209*	Substitution - Nonsense	2:29220726-29220726,	PATHOGENIC	0.96264	22675565
ALK	427	COSM327053,	large_intestine	carcinoid-endocrine_tumour	p.R1209*	Substitution - Nonsense	2:29220726-29220726,	PATHOGENIC	0.96264	28481359
ALK	427	COSM6974984,	lung	carcinoma	p.F255L	Substitution - Missense	2:29717600-29717600,	PATHOGENIC	0.96172	28481359
ALK	427	COSM48230,	lung	carcinoma	p.P542R	Substitution - Missense	2:29318326-29318326,	PATHOGENIC	0.96031	18948947
ALK	427	COSM6915904,	large_intestine	carcinoma	p.P1415S	Substitution - Missense	2:29193844-29193844,	PATHOGENIC	0.9602	28481359
ALK	427	COSM6598537,	pancreas	carcinoma	p.A1396T	Substitution - Missense	2:29193901-29193901,	PATHOGENIC	0.96003	28481359
ALK	427	COSM4989838,	autonomic_ganglia	neuroblastoma	p.T1343I	Substitution - Missense	2:29197587-29197587,	PATHOGENIC	0.95945	25517749
ALK	427	COSM5607769,	skin	malignant_melanoma	p.I543S	Substitution - Missense	2:29318323-29318323,	PATHOGENIC	0.95921	26343386
ALK	427	COSM6972789,	lung	carcinoma	p.E1299Q	Substitution - Missense	2:29207214-29207214,	PATHOGENIC	0.95911	28481359
ALK	427	COSM5417525,	endometrium	carcinoma	p.S546F	Substitution - Missense	2:29318314-29318314,	PATHOGENIC	0.95831	25233892
ALK	427	COSM28062,	autonomic_ganglia	neuroblastoma	p.F1245L	Substitution - Missense	2:29213992-29213992,	PATHOGENIC	0.95738	18923524
ALK	427	COSM6948367,	lung	carcinoma	p.P542Q	Substitution - Missense	2:29318326-29318326,	PATHOGENIC	0.95734	28481359
ALK	427	COSM5575702,	stomach	carcinoma	p.W1295C	Substitution - Missense	2:29207224-29207224,	PATHOGENIC	0.95716	26489445
ALK	427	COSM4991726,	skin	carcinoma	p.G1286R	Substitution - Missense	2:29207253-29207253,	PATHOGENIC	0.95633	25589618
ALK	427	COSM6961013,	bone	osteosarcoma	p.V1019L	Substitution - Missense	2:29226934-29226934,	PATHOGENIC	0.95624	28481359
ALK	427	COSM93896,	breast	carcinoma	p.I393N	Substitution - Missense	2:29383836-29383836,	PATHOGENIC	0.95604	20668451
ALK	427	COSM5607761,	skin	malignant_melanoma	p.P1331L	Substitution - Missense	2:29197623-29197623,	PATHOGENIC	0.956	26343386
ALK	427	COSM1531769,	skin	adnexal_tumour	p.G875R	Substitution - Missense	2:29232313-29232313,	PATHOGENIC	0.95455	27287813
ALK	427	COSM5575864,	stomach	carcinoma	p.P1357S	Substitution - Missense	2:29197546-29197546,	PATHOGENIC	0.95279	26489445
ALK	427	COSM2941508,	thyroid	adenoma-nodule-goitre	p.R753Q	Substitution - Missense	2:29239777-29239777,	PATHOGENIC	0.95253	28481359
ALK	427	COSM28493,	autonomic_ganglia	neuroblastoma	p.F1245L	Substitution - Missense	2:29213992-29213992,	PATHOGENIC	0.95169	23084186
ALK	427	COSM28493,	autonomic_ganglia	neuroblastoma	p.F1245L	Substitution - Missense	2:29213992-29213992,	PATHOGENIC	0.95169	23084186
ALK	427	COSM28493,	autonomic_ganglia	neuroblastoma	p.F1245L	Substitution - Missense	2:29213992-29213992,	PATHOGENIC	0.95169	18990089
ALK	427	COSM28493,	autonomic_ganglia	neuroblastoma	p.F1245L	Substitution - Missense	2:29213992-29213992,	PATHOGENIC	0.95169	25517749
ALK	427	COSM6935109,	soft_tissue	angiosarcoma	p.S1042A	Substitution - Missense	2:29225509-29225509,	PATHOGENIC	0.95066	28481359
ALK	427	COSM6979884,	lung	carcinoma	p.P542L	Substitution - Missense	2:29318326-29318326,	PATHOGENIC	0.9505	28481359
ALK	427	COSM6938928,	large_intestine	carcinoma	p.E1605V	Substitution - Missense	2:29193273-29193273,	PATHOGENIC	0.95005	28481359
ALK	427	COSM6938928,	large_intestine	carcinoma	p.E1605V	Substitution - Missense	2:29193273-29193273,	PATHOGENIC	0.95005	28481359
ALK	427	COSM3910211,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G1304E	Substitution - Missense	2:29207198-29207198,	PATHOGENIC	0.94902	28481359
ALK	427	COSM3910211,	skin	malignant_melanoma	p.G1304E	Substitution - Missense	2:29207198-29207198,	PATHOGENIC	0.94902	26343386
ALK	427	COSM6913817,	small_intestine	carcinoma	p.A699E	Substitution - Missense	2:29251213-29251213,	PATHOGENIC	0.94893	28481359
ALK	427	COSM6949625,	pancreas	carcinoma	p.S1086L	Substitution - Missense	2:29223444-29223444,	PATHOGENIC	0.94876	28481359
ALK	427	COSM6968467,	central_nervous_system	glioma	p.G818E	Substitution - Missense	2:29233599-29233599,	PATHOGENIC	0.94783	28481359
ALK	427	COSM6949821,	urinary_tract	carcinoma	p.L774M	Substitution - Missense	2:29239715-29239715,	PATHOGENIC	0.94706	28481359
ALK	427	COSM6926947,	lung	carcinoma	p.P835S	Substitution - Missense	2:29232433-29232433,	PATHOGENIC	0.94705	28481359
ALK	427	COSM6963710,	large_intestine	carcinoma	p.P948L	Substitution - Missense	2:29227645-29227645,	PATHOGENIC	0.94489	28481359
ALK	427	COSM6926433,	lung	carcinoma	p.R557G	Substitution - Missense	2:29297036-29297036,	PATHOGENIC	0.94476	28481359
ALK	427	COSM6939221,	large_intestine	carcinoma	p.T1310A	Substitution - Missense	2:29207181-29207181,	PATHOGENIC	0.94396	28481359
ALK	427	COSM6911625,	lung	carcinoma	p.P599H	Substitution - Missense	2:29296909-29296909,	PATHOGENIC	0.94308	28481359
ALK	427	COSM20713,	ovary	carcinoma	p.R401*	Substitution - Nonsense	2:29383813-29383813,	PATHOGENIC	0.94169	Info_not_available
ALK	427	COSM20713,	ovary	carcinoma	p.R401*	Substitution - Nonsense	2:29383813-29383813,	PATHOGENIC	0.94169	Info_not_available
ALK	427	COSM20713,	skin	malignant_melanoma	p.R401*	Substitution - Nonsense	2:29383813-29383813,	PATHOGENIC	0.94169	28481359
ALK	427	COSM20713,	large_intestine	carcinoma	p.R401*	Substitution - Nonsense	2:29383813-29383813,	PATHOGENIC	0.94169	28481359
ALK	427	COSM20713,	large_intestine	carcinoma	p.R401*	Substitution - Nonsense	2:29383813-29383813,	PATHOGENIC	0.94169	28481359
ALK	427	COSM20713,	endometrium	carcinoma	p.R401*	Substitution - Nonsense	2:29383813-29383813,	PATHOGENIC	0.94169	25233892
ALK	427	COSM6931095,	soft_tissue	solitary_fibrous_tumour	p.Q1177H	Substitution - Missense	2:29220820-29220820,	PATHOGENIC	0.93904	28481359
ALK	427	COSM4661140,	lung	carcinoma	p.L389F	Substitution - Missense	2:29383849-29383849,	PATHOGENIC	0.93733	28481359
ALK	427	COSM6909821,	prostate	carcinoma	p.R1347L	Substitution - Missense	2:29197575-29197575,	PATHOGENIC	0.93712	28481359
ALK	427	COSM6932191,	skin	carcinoma	p.N884I	Substitution - Missense	2:29229048-29229048,	PATHOGENIC	0.93561	28481359
ALK	427	COSM6914531,	oesophagus	carcinoma	p.G410R	Substitution - Missense	2:29383786-29383786,	PATHOGENIC	0.93556	28481359
ALK	427	COSM6913600,	central_nervous_system	glioma	p.W386*	Substitution - Nonsense	2:29383856-29383856,	PATHOGENIC	0.93556	28481359
ALK	427	COSM6929448,	lung	carcinoma	p.D605H	Substitution - Missense	2:29296892-29296892,	PATHOGENIC	0.9351	28481359
ALK	427	COSM6948091,	large_intestine	carcinoma	p.R1231L	Substitution - Missense	2:29214035-29214035,	PATHOGENIC	0.93412	28481359
ALK	427	COSM5396884,	NS	malignant_melanoma	p.E405K	Substitution - Missense	2:29383801-29383801,	PATHOGENIC	0.93391	28481359
ALK	427	COSM6933291,	breast	carcinoma	p.E859D	Substitution - Missense	2:29232359-29232359,	PATHOGENIC	0.93365	28481359
ALK	427	COSM6979095,	lung	carcinoma	p.P336Q	Substitution - Missense	2:29532062-29532062,	PATHOGENIC	0.93176	28481359
ALK	427	COSM225462,	endometrium	carcinoma	p.R557C	Substitution - Missense	2:29297036-29297036,	PATHOGENIC	0.93152	25233892
ALK	427	COSM225462,	skin	malignant_melanoma	p.R557C	Substitution - Missense	2:29297036-29297036,	PATHOGENIC	0.93152	28481359
ALK	427	COSM225462,	penis	carcinoma	p.R557C	Substitution - Missense	2:29297036-29297036,	PATHOGENIC	0.93152	28481359
ALK	427	COSM6919828,	prostate	carcinoma	p.V1019I	Substitution - Missense	2:29226934-29226934,	PATHOGENIC	0.93048	28481359
ALK	427	COSM6909823,	placenta	choriocarcinoma	p.G574W	Substitution - Missense	2:29296985-29296985,	PATHOGENIC	0.92984	28481359
ALK	427	COSM6918436,	urinary_tract	carcinoma	p.Y1330C	Substitution - Missense	2:29197626-29197626,	PATHOGENIC	0.92711	28481359
ALK	427	COSM5607782,	skin	malignant_melanoma	p.G1326E	Substitution - Missense	2:29197638-29197638,	PATHOGENIC	0.92669	26343386
ALK	427	COSM4977004,	breast	carcinoma	p.E1409D	Substitution - Missense	2:29193860-29193860,	PATHOGENIC	0.92665	28481359
ALK	427	COSM442798,	skin	adnexal_tumour	p.R1275*	Substitution - Nonsense	2:29209799-29209799,	PATHOGENIC	0.9265	27311873
ALK	427	COSM442798,	central_nervous_system	glioma	p.R1275*	Substitution - Nonsense	2:29209799-29209799,	PATHOGENIC	0.9265	28201779
ALK	427	COSM4989839,	autonomic_ganglia	neuroblastoma	p.D1349H	Substitution - Missense	2:29197570-29197570,	PATHOGENIC	0.92589	25517749
ALK	427	COSM6967207,	lung	carcinoma	p.L1145M	Substitution - Missense	2:29222534-29222534,	PATHOGENIC	0.92492	28481359
ALK	427	COSM5607778,	skin	malignant_melanoma	p.S289F	Substitution - Missense	2:29694936-29694936,	PATHOGENIC	0.92472	26343386
ALK	427	COSM6924954,	central_nervous_system	glioma	p.R1347Q	Substitution - Missense	2:29197575-29197575,	PATHOGENIC	0.92412	28481359
ALK	427	COSM28063,	autonomic_ganglia	neuroblastoma	p.K1062M	Substitution - Missense	2:29223516-29223516,	PATHOGENIC	0.92364	18923524
ALK	427	COSM1130802,	soft_tissue	haemangioblastoma	p.K1491R	Substitution - Missense	2:29193615-29193615,	PATHOGENIC	0.92214	25589003
ALK	427	COSM1130802,	soft_tissue	haemangioblastoma	p.K1491R	Substitution - Missense	2:29193615-29193615,	PATHOGENIC	0.92214	25589003
ALK	427	COSM1130802,	soft_tissue	haemangioblastoma	p.K1491R	Substitution - Missense	2:29193615-29193615,	PATHOGENIC	0.92214	25589003
ALK	427	COSM1130802,	soft_tissue	haemangioblastoma	p.K1491R	Substitution - Missense	2:29193615-29193615,	PATHOGENIC	0.92214	25589003
ALK	427	COSM1130802,	soft_tissue	haemangioblastoma	p.K1491R	Substitution - Missense	2:29193615-29193615,	PATHOGENIC	0.92214	25589003
ALK	427	COSM1130802,	soft_tissue	haemangioblastoma	p.K1491R	Substitution - Missense	2:29193615-29193615,	PATHOGENIC	0.92214	25589003
ALK	427	COSM1130802,	soft_tissue	haemangioblastoma	p.K1491R	Substitution - Missense	2:29193615-29193615,	PATHOGENIC	0.92214	25589003
ALK	427	COSM1130802,	soft_tissue	haemangioblastoma	p.K1491R	Substitution - Missense	2:29193615-29193615,	PATHOGENIC	0.92214	25589003
ALK	427	COSM6922788,	NS	malignant_melanoma	p.F441L	Substitution - Missense	2:29328441-29328441,	PATHOGENIC	0.92165	28481359
ALK	427	COSM6920292,	skin	malignant_melanoma	p.D1417N	Substitution - Missense	2:29193838-29193838,	PATHOGENIC	0.92105	28481359
ALK	427	COSM6920292,	soft_tissue	angiosarcoma	p.D1417N	Substitution - Missense	2:29193838-29193838,	PATHOGENIC	0.92105	28481359
ALK	427	COSM28502,	autonomic_ganglia	neuroblastoma	p.D1091N	Substitution - Missense	2:29223430-29223430,	PATHOGENIC	0.91965	23202128
ALK	427	COSM28502,	autonomic_ganglia	neuroblastoma	p.D1091N	Substitution - Missense	2:29223430-29223430,	PATHOGENIC	0.91965	18724359
ALK	427	COSM28502,	autonomic_ganglia	neuroblastoma	p.D1091N	Substitution - Missense	2:29223430-29223430,	PATHOGENIC	0.91965	18923525
ALK	427	COSM6911177,	breast	carcinoma	p.S1487L	Substitution - Missense	2:29193627-29193627,	PATHOGENIC	0.91884	28481359
ALK	427	COSM5607773,	skin	malignant_melanoma	p.S299F	Substitution - Missense	2:29694906-29694906,	PATHOGENIC	0.91852	26343386
ALK	427	COSM3364723,	lung	carcinoma	p.D954N	Substitution - Missense	2:29227628-29227628,	PATHOGENIC	0.91744	28481359
ALK	427	COSM6954289,	urinary_tract	carcinoma	p.K313T	Substitution - Missense	2:29694864-29694864,	PATHOGENIC	0.91717	28481359
ALK	427	COSM6965823,	skin	malignant_melanoma	p.G562E	Substitution - Missense	2:29297020-29297020,	PATHOGENIC	0.91472	28481359
ALK	427	COSM5607768,	skin	malignant_melanoma	p.E570K	Substitution - Missense	2:29296997-29296997,	PATHOGENIC	0.91472	26343386
ALK	427	COSM4807894,	large_intestine	carcinoma	p.G574R	Substitution - Missense	2:29296985-29296985,	PATHOGENIC	0.91191	27023146
ALK	427	COSM4807894,	large_intestine	carcinoma	p.G574R	Substitution - Missense	2:29296985-29296985,	PATHOGENIC	0.91191	27023146
ALK	427	COSM4807894,	large_intestine	carcinoma	p.G574R	Substitution - Missense	2:29296985-29296985,	PATHOGENIC	0.91191	27023146
ALK	427	COSM4807894,	large_intestine	carcinoma	p.G574R	Substitution - Missense	2:29296985-29296985,	PATHOGENIC	0.91191	27023146
ALK	427	COSM4807894,	urinary_tract	carcinoma	p.G574R	Substitution - Missense	2:29296985-29296985,	PATHOGENIC	0.91191	28481359
ALK	427	COSM4807894,	large_intestine	carcinoma	p.G574R	Substitution - Missense	2:29296985-29296985,	PATHOGENIC	0.91191	27023146
ALK	427	COSM6917541,	lung	carcinoma	p.P679H	Substitution - Missense	2:29275104-29275104,	PATHOGENIC	0.91109	28481359
ALK	427	COSM5945887,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R606G	Substitution - Missense	2:29296889-29296889,	PATHOGENIC	0.91045	26773734
ALK	427	COSM6983440,	large_intestine	carcinoma	p.H1228Y	Substitution - Missense	2:29214045-29214045,	PATHOGENIC	0.90742	28481359
ALK	427	COSM50278,	large_intestine	carcinoma	p.R401Q	Substitution - Missense	2:29383812-29383812,	PATHOGENIC	0.90717	17932254
ALK	427	COSM5020538,	soft_tissue	haemangioblastoma	p.G488G	Substitution - coding silent	2:29320833-29320833,	PATHOGENIC	0.90654	25589003
ALK	427	COSM6963195,	skin	malignant_melanoma	p.G715E	Substitution - Missense	2:29251165-29251165,	PATHOGENIC	0.90203	28481359
ALK	427	COSM6915076,	lung	carcinoma	p.V827L	Substitution - Missense	2:29233573-29233573,	PATHOGENIC	0.89931	28481359
ALK	427	COSM6912975,	lung	carcinoma	p.L566F	Substitution - Missense	2:29297007-29297007,	PATHOGENIC	0.89831	28481359
ALK	427	COSM6948500,	oesophagus	carcinoma	p.L550I	Substitution - Missense	2:29297057-29297057,	PATHOGENIC	0.89799	28481359
ALK	427	COSM5019540,	ovary	carcinoma	p.T680I	Substitution - Missense	2:29275101-29275101,	PATHOGENIC	0.89676	28481359
ALK	427	COSM5019540,	soft_tissue	haemangioblastoma	p.T680I	Substitution - Missense	2:29275101-29275101,	PATHOGENIC	0.89676	25589003
ALK	427	COSM6946972,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.P679S	Substitution - Missense	2:29275105-29275105,	PATHOGENIC	0.89676	28481359
ALK	427	COSM5019540,	soft_tissue	haemangioblastoma	p.T680I	Substitution - Missense	2:29275101-29275101,	PATHOGENIC	0.89676	25589003
ALK	427	COSM6984000,	lung	carcinoma	p.G428A	Substitution - Missense	2:29328481-29328481,	PATHOGENIC	0.89588	28481359
ALK	427	COSM2941535,	lung	carcinoma	p.R395C	Substitution - Missense	2:29383831-29383831,	PATHOGENIC	0.89484	28481359
ALK	427	COSM1182537,	endometrium	carcinoma	p.R551*	Substitution - Nonsense	2:29297054-29297054,	PATHOGENIC	0.89254	28481359
ALK	427	COSM5047626,	oesophagus	carcinoma	p.E657Q	Substitution - Missense	2:29275171-29275171,	PATHOGENIC	0.88958	24686850
ALK	427	COSM5047014,	oesophagus	carcinoma	p.E549Q	Substitution - Missense	2:29318306-29318306,	PATHOGENIC	0.88884	24686850
ALK	427	COSM5047501,	oesophagus	carcinoma	p.P1559S	Substitution - Missense	2:29193412-29193412,	PATHOGENIC	0.88672	24686850
ALK	427	COSM6932461,	lung	carcinoma	p.P948T	Substitution - Missense	2:29227646-29227646,	PATHOGENIC	0.88452	28481359
ALK	427	COSM6980069,	lung	carcinoma	p.D642Y	Substitution - Missense	2:29275216-29275216,	PATHOGENIC	0.88433	28481359
ALK	427	COSM6916118,	lung	carcinoma	p.G199S	Substitution - Missense	2:29920065-29920065,	PATHOGENIC	0.88205	28481359
ALK	427	COSM6598514,	breast	carcinoma	p.V349I	Substitution - Missense	2:29532024-29532024,	PATHOGENIC	0.88053	28481359
ALK	427	COSM6598514,	large_intestine	carcinoma	p.V349I	Substitution - Missense	2:29532024-29532024,	PATHOGENIC	0.88053	28481359
ALK	427	COSM1407680,	large_intestine	carcinoma	p.R291C	Substitution - Missense	2:29694931-29694931,	PATHOGENIC	0.87863	28481359
ALK	427	COSM1407680,	large_intestine	carcinoma	p.R291C	Substitution - Missense	2:29694931-29694931,	PATHOGENIC	0.87863	28481359
ALK	427	COSM1407680,	soft_tissue	perivascular_epithelioid_cell_tumour_(PEComa)	p.R291C	Substitution - Missense	2:29694931-29694931,	PATHOGENIC	0.87863	28481359
ALK	427	COSM1407680,	large_intestine	carcinoma	p.R291C	Substitution - Missense	2:29694931-29694931,	PATHOGENIC	0.87863	28481359
ALK	427	COSM1407680,	large_intestine	carcinoma	p.R291C	Substitution - Missense	2:29694931-29694931,	PATHOGENIC	0.87863	28481359
ALK	427	COSM1407680,	large_intestine	carcinoma	p.R291C	Substitution - Missense	2:29694931-29694931,	PATHOGENIC	0.87863	28481359
ALK	427	COSM6926962,	lung	carcinoma	p.S62L	Substitution - Missense	2:29920475-29920475,	PATHOGENIC	0.87749	28481359
ALK	427	COSM6926962,	lung	carcinoma	p.S62L	Substitution - Missense	2:29920475-29920475,	PATHOGENIC	0.87749	28481359
ALK	427	COSM6981820,	skin	malignant_melanoma	p.S553F	Substitution - Missense	2:29297047-29297047,	PATHOGENIC	0.8771	28481359
ALK	427	COSM28494,	autonomic_ganglia	neuroblastoma	p.R1061Q	Substitution - Missense	2:29223519-29223519,	PATHOGENIC	0.87643	18990089
ALK	427	COSM4093778,	upper_aerodigestive_tract	carcinoma	p.E343Q	Substitution - Missense	2:29532042-29532042,	PATHOGENIC	0.87625	28481359
ALK	427	COSM6946725,	testis	germ_cell_tumour	p.T325N	Substitution - Missense	2:29532095-29532095,	PATHOGENIC	0.87551	28481359
ALK	427	COSM5967491,	skin	malignant_melanoma	p.R1231Q	Substitution - Missense	2:29214035-29214035,	PATHOGENIC	0.87495	28481359
ALK	427	COSM5967491,	lung	carcinoma	p.R1231Q	Substitution - Missense	2:29214035-29214035,	PATHOGENIC	0.87495	26599269
ALK	427	COSM5862407,	lung	carcinoma	p.R606K	Substitution - Missense	2:29296888-29296888,	PATHOGENIC	0.87429	28481359
ALK	427	COSM48231,	lung	carcinoma	p.P496L	Substitution - Missense	2:29320810-29320810,	PATHOGENIC	0.87254	18948947
ALK	427	COSM6914239,	skin	carcinoma	p.Y361C	Substitution - Missense	2:29531987-29531987,	PATHOGENIC	0.87235	28481359
ALK	427	COSM6915296,	lung	carcinoma	p.V834A	Substitution - Missense	2:29232435-29232435,	PATHOGENIC	0.87208	28481359
ALK	427	COSM6966099,	skin	malignant_melanoma	p.K1082R	Substitution - Missense	2:29223456-29223456,	PATHOGENIC	0.87191	28481359
ALK	427	COSM6969211,	soft_tissue	leiomyosarcoma	p.K330E	Substitution - Missense	2:29532081-29532081,	PATHOGENIC	0.87118	28481359
ALK	427	COSM6936364,	lung	carcinoma	p.P1456H	Substitution - Missense	2:29193720-29193720,	PATHOGENIC	0.8672	28481359
ALK	427	COSM6924434,	stomach	carcinoid-endocrine_tumour	p.M1069L	Substitution - Missense	2:29223496-29223496,	PATHOGENIC	0.86577	28481359
ALK	427	COSM6941323,	breast	carcinoma	p.H281D	Substitution - Missense	2:29694961-29694961,	PATHOGENIC	0.86523	28481359
ALK	427	COSM48229,	lung	carcinoma	p.S631I	Substitution - Missense	2:29275422-29275422,	PATHOGENIC	0.86463	18948947
ALK	427	COSM5369888,	cervix	carcinoma	p.D466N	Substitution - Missense	2:29328368-29328368,	PATHOGENIC	0.86444	25626421
ALK	427	COSM6945355,	skin	carcinoma	p.E465K	Substitution - Missense	2:29328371-29328371,	PATHOGENIC	0.86444	28481359
ALK	427	COSM5607763,	skin	malignant_melanoma	p.G428E	Substitution - Missense	2:29328481-29328481,	PATHOGENIC	0.86372	26343386
ALK	427	COSM6921893,	lung	carcinoma	p.L376V	Substitution - Missense	2:29531943-29531943,	PATHOGENIC	0.86205	28481359
ALK	427	COSM6949636,	endometrium	carcinoma	p.D456G	Substitution - Missense	2:29328397-29328397,	PATHOGENIC	0.85925	28481359
ALK	427	COSM6995484,	ovary	germ_cell_tumour	p.E370Q	Substitution - Missense	2:29531961-29531961,	PATHOGENIC	0.85841	28954785
ALK	427	COSM5607775,	skin	malignant_melanoma	p.V417V	Substitution - coding silent	2:29383763-29383763,	PATHOGENIC	0.8581	26343386
ALK	427	COSM6965489,	urinary_tract	carcinoma	p.E265K	Substitution - Missense	2:29695009-29695009,	PATHOGENIC	0.85275	28481359
ALK	427	COSM98492,	autonomic_ganglia	neuroblastoma	p.L1240V	Substitution - Missense	2:29214009-29214009,	PATHOGENIC	0.85211	25517749
ALK	427	COSM98492,	autonomic_ganglia	neuroblastoma	p.L1240V	Substitution - Missense	2:29214009-29214009,	PATHOGENIC	0.85211	21632861
ALK	427	COSM6921909,	lung	carcinoma	p.I630M	Substitution - Missense	2:29275424-29275424,	PATHOGENIC	0.85071	28481359
ALK	427	COSM6963778,	breast	carcinoma	p.E570D	Substitution - Missense	2:29296995-29296995,	PATHOGENIC	0.85031	28481359
ALK	427	COSM6977528,	lung	carcinoma	p.Q706*	Substitution - Nonsense	2:29251193-29251193,	PATHOGENIC	0.84977	28481359
ALK	427	COSM6923917,	central_nervous_system	glioma	p.G452E	Substitution - Missense	2:29328409-29328409,	PATHOGENIC	0.84368	28481359
ALK	427	COSM6006339,	endometrium	carcinoma	p.R1084C	Substitution - Missense	2:29223451-29223451,	PATHOGENIC	0.84284	28481359
ALK	427	COSM6006339,	skin	adnexal_tumour	p.R1084C	Substitution - Missense	2:29223451-29223451,	PATHOGENIC	0.84284	27287813
ALK	427	COSM5417524,	endometrium	carcinoma	p.H281Y	Substitution - Missense	2:29694961-29694961,	PATHOGENIC	0.84199	25233892
ALK	427	COSM5607772,	skin	malignant_melanoma	p.I676I	Substitution - coding silent	2:29275112-29275112,	PATHOGENIC	0.84075	26343386
ALK	427	COSM2941481,	stomach	carcinoma	p.E949K	Substitution - Missense	2:29227643-29227643,	PATHOGENIC	0.83588	28481359
ALK	427	COSM6967822,	skin	carcinoma	p.G589D	Substitution - Missense	2:29296939-29296939,	PATHOGENIC	0.83416	28481359
ALK	427	COSM5607776,	skin	malignant_melanoma	p.V1476L	Substitution - Missense	2:29193661-29193661,	PATHOGENIC	0.83338	26343386
ALK	427	COSM6971970,	small_intestine	carcinoma	p.A624T	Substitution - Missense	2:29275444-29275444,	PATHOGENIC	0.831	28481359
ALK	427	COSM6945797,	NS	carcinoma	p.L63I	Substitution - Missense	2:29920473-29920473,	PATHOGENIC	0.83002	28481359
ALK	427	COSM327054,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N808N	Substitution - coding silent	2:29233628-29233628,	PATHOGENIC	0.82882	22675565
ALK	427	COSM6979247,	lung	carcinoma	p.P1027L	Substitution - Missense	2:29225553-29225553,	PATHOGENIC	0.82696	28481359
ALK	427	COSM6943111,	skin	malignant_melanoma	p.N764S	Substitution - Missense	2:29239744-29239744,	PATHOGENIC	0.82239	28481359
ALK	427	COSM6923890,	breast	carcinoma	p.R291P	Substitution - Missense	2:29694930-29694930,	PATHOGENIC	0.81445	28481359
ALK	427	COSM2941538,	urinary_tract	carcinoma	p.P379S	Substitution - Missense	2:29531934-29531934,	PATHOGENIC	0.81092	28481359
ALK	427	COSM6950335,	lung	carcinoma	p.Q502H	Substitution - Missense	2:29320791-29320791,	PATHOGENIC	0.80753	28481359
ALK	427	COSM5646334,	lung	carcinoma	p.E370K	Substitution - Missense	2:29531961-29531961,	PATHOGENIC	0.80091	28481359
ALK	427	COSM5646334,	skin	malignant_melanoma	p.E370K	Substitution - Missense	2:29531961-29531961,	PATHOGENIC	0.80091	28481359
ALK	427	COSM6987699,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R184Q	Substitution - Missense	2:29920109-29920109,	PATHOGENIC	0.80066	28481359
ALK	427	COSM5607784,	skin	malignant_melanoma	p.L774L	Substitution - coding silent	2:29239715-29239715,	PATHOGENIC	0.79852	26343386
ALK	427	COSM6976582,	central_nervous_system	glioma	p.I805N	Substitution - Missense	2:29233638-29233638,	PATHOGENIC	0.79847	28481359
ALK	427	COSM6906723,	breast	carcinoma	p.H368Q	Substitution - Missense	2:29531965-29531965,	PATHOGENIC	0.79831	29420467
ALK	427	COSM6912792,	thyroid	carcinoma	p.K1079N	Substitution - Missense	2:29223464-29223464,	PATHOGENIC	0.79623	28481359
ALK	427	COSM1020029,	large_intestine	carcinoma	p.R214H	Substitution - Missense	2:29920019-29920019,	PATHOGENIC	0.79448	28481359
ALK	427	COSM1020029,	endometrium	carcinoma	p.R214H	Substitution - Missense	2:29920019-29920019,	PATHOGENIC	0.79448	28481359
ALK	427	COSM5417522,	endometrium	carcinoma	p.R1347W	Substitution - Missense	2:29197576-29197576,	PATHOGENIC	0.79227	25233892
ALK	427	COSM6917062,	ovary	carcinoma	p.E297D	Substitution - Missense	2:29694911-29694911,	PATHOGENIC	0.7898	28481359
ALK	427	COSM6986476,	urinary_tract	carcinoma	p.E1605K	Substitution - Missense	2:29193274-29193274,	PATHOGENIC	0.7898	28481359
ALK	427	COSM1717565,	endometrium	carcinoma	p.R209H	Substitution - Missense	2:29920034-29920034,	PATHOGENIC	0.78573	25233892
ALK	427	COSM6929447,	lung	carcinoma	p.P999H	Substitution - Missense	2:29226993-29226993,	PATHOGENIC	0.78464	28481359
ALK	427	COSM95759,	lung	carcinoma	p.H344H	Substitution - coding silent	2:29532037-29532037,	PATHOGENIC	0.78319	20668451
ALK	427	COSM6976749,	central_nervous_system	glioma	p.C95Y	Substitution - Missense	2:29920376-29920376,	PATHOGENIC	0.77719	28481359
ALK	427	COSM6972905,	skin	carcinoma	p.P357L	Substitution - Missense	2:29531999-29531999,	PATHOGENIC	0.77707	28481359
ALK	427	COSM6972905,	skin	malignant_melanoma	p.P357L	Substitution - Missense	2:29531999-29531999,	PATHOGENIC	0.77707	28481359
ALK	427	COSM6854510,	large_intestine	carcinoma	p.R291L	Substitution - Missense	2:29694930-29694930,	PATHOGENIC	0.77642	28524162
ALK	427	COSM6936205,	NS	malignant_melanoma	p.W177*	Substitution - Nonsense	2:29920130-29920130,	PATHOGENIC	0.7758	28481359
ALK	427	COSM6936205,	skin	malignant_melanoma	p.W177*	Substitution - Nonsense	2:29920130-29920130,	PATHOGENIC	0.7758	28481359
ALK	427	COSM6919518,	lung	carcinoma	p.Y635*	Substitution - Nonsense	2:29275409-29275409,	PATHOGENIC	0.77089	28481359
ALK	427	COSM6920030,	lung	carcinoma	p.W595*	Substitution - Nonsense	2:29296921-29296921,	PATHOGENIC	0.76948	28481359
ALK	427	COSM5607783,	skin	malignant_melanoma	p.W595*	Substitution - Nonsense	2:29296920-29296920,	PATHOGENIC	0.76692	26343386
ALK	427	COSM6918911,	prostate	carcinoma	p.H331R	Substitution - Missense	2:29532077-29532077,	PATHOGENIC	0.75592	28481359
ALK	427	COSM6971679,	NS	malignant_melanoma	p.S735N	Substitution - Missense	2:29251105-29251105,	PATHOGENIC	0.75545	28481359
ALK	427	COSM6918431,	urinary_tract	carcinoma	p.R412C	Substitution - Missense	2:29383780-29383780,	PATHOGENIC	0.75189	28481359
ALK	427	COSM93895,	breast	carcinoma	p.H458Q	Substitution - Missense	2:29328390-29328390,	PATHOGENIC	0.72919	20668451
ALK	427	COSM6970704,	lung	carcinoma	p.E148*	Substitution - Nonsense	2:29920218-29920218,	PATHOGENIC	0.72774	28481359
ALK	427	COSM6910086,	lung	carcinoma	p.P1260T	Substitution - Missense	2:29209844-29209844,	PATHOGENIC	0.72719	28481359
ALK	427	COSM6960757,	stomach	carcinoma	p.C272W	Substitution - Missense	2:29694986-29694986,	PATHOGENIC	0.71549	28481359
ALK	427	COSM6960757,	stomach	carcinoma	p.C272W	Substitution - Missense	2:29694986-29694986,	PATHOGENIC	0.71549	28481359
ALK	427	COSM6931619,	central_nervous_system	glioma	p.S430F	Substitution - Missense	2:29328475-29328475,	PATHOGENIC	0.71382	28481359
ALK	427	COSM5607765,	skin	malignant_melanoma	p.Q450*	Substitution - Nonsense	2:29328416-29328416,	PATHOGENIC	0.71117	26343386
ALK	427	COSM6969155,	thyroid	carcinoma	p.E663Q	Substitution - Missense	2:29275153-29275153,	PATHOGENIC	0.70561	28481359
ALK	427	COSM6920722,	lung	carcinoma	p.C154F	Substitution - Missense	2:29920199-29920199,	PATHOGENIC	0.70173	28481359
ALK	427	COSM3581012,	skin	malignant_melanoma	p.F270F	Substitution - coding silent	2:29694992-29694992,	NEUTRAL	0.49699	26343386
ALK	427	COSM1172867,	soft_tissue	liposarcoma	p.R395H	Substitution - Missense	2:29383830-29383830,	NEUTRAL	0.49249	28481359
ALK	427	COSM1172867,	large_intestine	carcinoma	p.R395H	Substitution - Missense	2:29383830-29383830,	NEUTRAL	0.49249	28481359
ALK	427	COSM1172867,	large_intestine	carcinoma	p.R395H	Substitution - Missense	2:29383830-29383830,	NEUTRAL	0.49249	28481359
ALK	427	COSM1172867,	stomach	carcinoma	p.R395H	Substitution - Missense	2:29383830-29383830,	NEUTRAL	0.49249	28481359
ALK	427	COSM1172867,	large_intestine	carcinoma	p.R395H	Substitution - Missense	2:29383830-29383830,	NEUTRAL	0.49249	28481359
ALK	427	COSM1172867,	skin	carcinoma	p.R395H	Substitution - Missense	2:29383830-29383830,	NEUTRAL	0.49249	28481359
ALK	427	COSM6972873,	large_intestine	carcinoma	p.V59M	Substitution - Missense	2:29920485-29920485,	NEUTRAL	0.48478	28481359
ALK	427	COSM5607757,	skin	malignant_melanoma	p.L1257L	Substitution - coding silent	2:29209853-29209853,	NEUTRAL	0.46732	26343386
ALK	427	COSM6931063,	urinary_tract	carcinoma	p.V623M	Substitution - Missense	2:29275447-29275447,	NEUTRAL	0.46667	28481359
ALK	427	COSM1020030,	breast	carcinoma	p.A206V	Substitution - Missense	2:29920043-29920043,	NEUTRAL	0.45883	28481359
ALK	427	COSM6928319,	soft_tissue	other	p.E1460Q	Substitution - Missense	2:29193709-29193709,	NEUTRAL	0.42589	28481359
ALK	427	COSM6948696,	skin	malignant_melanoma	p.Q167*	Substitution - Nonsense	2:29920161-29920161,	NEUTRAL	0.4237	28481359
ALK	427	COSM5607760,	skin	malignant_melanoma	p.P527S	Substitution - Missense	2:29318372-29318372,	NEUTRAL	0.41296	26343386
ALK	427	COSM273947,	NS	malignant_melanoma	p.A1440V	Substitution - Missense	2:29193768-29193768,	NEUTRAL	0.41013	28481359
ALK	427	COSM6912889,	skin	carcinoma	p.G129S	Substitution - Missense	2:29920275-29920275,	NEUTRAL	0.40923	28481359
ALK	427	COSM6968262,	breast	carcinoma	p.G89S	Substitution - Missense	2:29920395-29920395,	NEUTRAL	0.39877	28481359
ALK	427	COSM6964644,	large_intestine	carcinoma	p.E172D	Substitution - Missense	2:29920144-29920144,	NEUTRAL	0.376	28481359
ALK	427	COSM6925851,	large_intestine	carcinoma	p.A327P	Substitution - Missense	2:29532090-29532090,	NEUTRAL	0.373	28481359
ALK	427	COSM6925851,	prostate	carcinoma	p.A327P	Substitution - Missense	2:29532090-29532090,	NEUTRAL	0.373	28481359
ALK	427	COSM4991733,	skin	carcinoma	p.S430S	Substitution - coding silent	2:29328474-29328474,	NEUTRAL	0.36598	25589618
ALK	427	COSM6943821,	pancreas	carcinoma	p.G432V	Substitution - Missense	2:29328469-29328469,	NEUTRAL	0.36363	28481359
ALK	427	COSM6908796,	lung	carcinoma	p.L598F	Substitution - Missense	2:29296911-29296911,	NEUTRAL	0.35573	28481359
ALK	427	COSM6909052,	breast	carcinoma	p.S131F	Substitution - Missense	2:29920268-29920268,	NEUTRAL	0.3193	28481359
ALK	427	COSM3580989,	lung	carcinoma	p.P675L	Substitution - Missense	2:29275116-29275116,	NEUTRAL	0.3145	28481359
ALK	427	COSM5607766,	skin	malignant_melanoma	p.G1537R	Substitution - Missense	2:29193478-29193478,	NEUTRAL	0.30304	26343386
ALK	427	COSM5589612,	skin	malignant_melanoma	p.R860K	Substitution - Missense	2:29232357-29232357,	NEUTRAL	0.29411	28481359
ALK	427	COSM166961,	bone	chordoma	p.A585T	Substitution - Missense	2:29296952-29296952,	NEUTRAL	0.29292	28481359
ALK	427	COSM166961,	large_intestine	carcinoma	p.A585T	Substitution - Missense	2:29296952-29296952,	NEUTRAL	0.29292	28481359
ALK	427	COSM166961,	large_intestine	carcinoma	p.A585T	Substitution - Missense	2:29296952-29296952,	NEUTRAL	0.29292	23700467
ALK	427	COSM6935176,	endometrium	carcinoma	p.S604P	Substitution - Missense	2:29296895-29296895,	NEUTRAL	0.29145	28481359
ALK	427	COSM6974611,	urinary_tract	carcinoma	p.S114L	Substitution - Missense	2:29920319-29920319,	NEUTRAL	0.28668	28481359
ALK	427	COSM5607774,	skin	malignant_melanoma	p.R472R	Substitution - coding silent	2:29320881-29320881,	NEUTRAL	0.28473	26343386
ALK	427	COSM6923316,	lung	carcinoma	p.R100S	Substitution - Missense	2:29920360-29920360,	NEUTRAL	0.2663	28481359
ALK	427	COSM6922992,	breast	carcinoma	p.D525Y	Substitution - Missense	2:29318378-29318378,	NEUTRAL	0.26608	28481359
ALK	427	COSM6973378,	liver	carcinoma	p.S1614R	Substitution - Missense	2:29193245-29193245,	NEUTRAL	0.26549	28481359
ALK	427	COSM5417526,	endometrium	carcinoma	p.G1494R	Substitution - Missense	2:29193607-29193607,	NEUTRAL	0.26418	25233892
ALK	427	COSM6005613,	prostate	carcinoma	p.P36S	Substitution - Missense	2:29920554-29920554,	NEUTRAL	0.24548	20579941
ALK	427	COSM591,	breast	carcinoma	p.L560F	Substitution - Missense	2:29297025-29297025,	NEUTRAL	0.23933	15908952
ALK	427	COSM591,	urinary_tract	carcinoma	p.L560F	Substitution - Missense	2:29297025-29297025,	NEUTRAL	0.23933	28481359
ALK	427	COSM6910743,	central_nervous_system	glioma	p.P1466L	Substitution - Missense	2:29193690-29193690,	NEUTRAL	0.22147	28481359
ALK	427	COSM6927793,	upper_aerodigestive_tract	carcinoma	p.P104S	Substitution - Missense	2:29920350-29920350,	NEUTRAL	0.19849	28481359
ALK	427	COSM5607770,	skin	malignant_melanoma	p.R121Q	Substitution - Missense	2:29920298-29920298,	NEUTRAL	0.1885	26343386
ALK	427	COSM5020048,	soft_tissue	haemangioblastoma	p.?	Unknown	2:29193928-29193928,	NEUTRAL	0.17606	25589003
ALK	427	COSM5020048,	soft_tissue	haemangioblastoma	p.?	Unknown	2:29193928-29193928,	NEUTRAL	0.17606	25589003
ALK	427	COSM5020048,	soft_tissue	haemangioblastoma	p.?	Unknown	2:29193928-29193928,	NEUTRAL	0.17606	25589003
ALK	427	COSM5020048,	soft_tissue	haemangioblastoma	p.?	Unknown	2:29193928-29193928,	NEUTRAL	0.17606	25589003
ALK	427	COSM5020048,	soft_tissue	haemangioblastoma	p.?	Unknown	2:29193928-29193928,	NEUTRAL	0.17606	25589003
ALK	427	COSM5020048,	soft_tissue	haemangioblastoma	p.?	Unknown	2:29193928-29193928,	NEUTRAL	0.17606	25589003
ALK	427	COSM6196760,	large_intestine	carcinoma	p.?	Unknown	2:29209883-29209883,	NEUTRAL	0.15636	27756406
ALK	427	COSM95757,	breast	carcinoma	p.L560L	Substitution - coding silent	2:29297025-29297025,	NEUTRAL	0.13492	20668451
ALK	427	COSM6979318,	endometrium	carcinoma	p.A509V	Substitution - Missense	2:29320771-29320771,	NEUTRAL	0.13	28481359
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM148825,	soft_tissue	haemangioblastoma	p.G845G	Substitution - coding silent	2:29232401-29232401,	NEUTRAL	0.12944	25589003
ALK	427	COSM6158008,	lung	carcinoma	p.V132L	Substitution - Missense	2:29920266-29920266,	NEUTRAL	0.12032	28481359
ALK	427	COSM6980131,	lung	carcinoma	p.V526F	Substitution - Missense	2:29318375-29318375,	NEUTRAL	0.11121	28481359
ALK	427	COSM28495,	autonomic_ganglia	neuroblastoma	p.T1211T	Substitution - coding silent	2:29220718-29220718,	NEUTRAL	0.0984	18990089
ALK	427	COSM28495,	autonomic_ganglia	neuroblastoma	p.T1211T	Substitution - coding silent	2:29220718-29220718,	NEUTRAL	0.0984	18990089
ALK	427	COSM28495,	autonomic_ganglia	neuroblastoma	p.T1211T	Substitution - coding silent	2:29220718-29220718,	NEUTRAL	0.0984	18990089
ALK	427	COSM6983406,	skin	malignant_melanoma	p.E713K	Substitution - Missense	2:29251172-29251172,	NEUTRAL	0.09793	28481359
ALK	427	COSM5607779,	skin	malignant_melanoma	p.A1280A	Substitution - coding silent	2:29207269-29207269,	NEUTRAL	0.09329	26343386
ALK	427	COSM6925638,	endometrium	carcinoma	p.G492C	Substitution - Missense	2:29320823-29320823,	NEUTRAL	0.09062	28481359
ALK	427	COSM6942029,	skin	malignant_melanoma	p.A120V	Substitution - Missense	2:29920301-29920301,	NEUTRAL	0.07407	28481359
ALK	427	COSM6972109,	lung	carcinoma	p.D282Y	Substitution - Missense	2:29694958-29694958,	NEUTRAL	0.06798	28481359
ALK	427	COSM3758202,	breast	carcinoma	p.V476A	Substitution - Missense	2:29320870-29320870,	NEUTRAL	0.05939	28481359
ALK	427	COSM6965738,	upper_aerodigestive_tract	carcinoma	p.L494V	Substitution - Missense	2:29320817-29320817,	NEUTRAL	0.05445	28481359
ALK	427	COSM6965738,	upper_aerodigestive_tract	carcinoma	p.L494V	Substitution - Missense	2:29320817-29320817,	NEUTRAL	0.05445	28481359
ALK	427	COSM95756,	lung	carcinoma	p.T1597T	Substitution - coding silent	2:29193296-29193296,	NEUTRAL	0.0539	20668451
ALK	427	COSM4661133,	central_nervous_system	glioma	p.D1529N	Substitution - Missense	2:29193502-29193502,	NEUTRAL	0.05335	28481359
ALK	427	COSM6938228,	breast	carcinoma	p.G22R	Substitution - Missense	2:29920596-29920596,	NEUTRAL	0.05268	28481359
ALK	427	COSM6938228,	urinary_tract	carcinoma	p.G22R	Substitution - Missense	2:29920596-29920596,	NEUTRAL	0.05268	28481359
ALK	427	COSM6973846,	urinary_tract	carcinoma	p.S78W	Substitution - Missense	2:29920427-29920427,	NEUTRAL	0.0523	28481359
ALK	427	COSM6928025,	lung	carcinoma	p.S430T	Substitution - Missense	2:29328476-29328476,	NEUTRAL	0.05196	28481359
ALK	427	COSM6910647,	lung	carcinoma	p.T648I	Substitution - Missense	2:29275197-29275197,	NEUTRAL	0.04979	28481359
ALK	427	COSM6978167,	endometrium	carcinoma	p.S15Y	Substitution - Missense	2:29920616-29920616,	NEUTRAL	0.04943	28481359
ALK	427	COSM327055,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P542P	Substitution - coding silent	2:29318325-29318325,	NEUTRAL	0.0489	22675565
ALK	427	COSM327055,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P542P	Substitution - coding silent	2:29318325-29318325,	NEUTRAL	0.0489	22675565
ALK	427	COSM1407661,	soft_tissue	haemangioblastoma	p.S1136S	Substitution - coding silent	2:29222559-29222559,	NEUTRAL	0.04567	25589003
ALK	427	COSM6967023,	endometrium	carcinoma	p.A586T	Substitution - Missense	2:29296949-29296949,	NEUTRAL	0.04314	28481359
ALK	427	COSM4661141,	large_intestine	carcinoma	p.A29T	Substitution - Missense	2:29920575-29920575,	NEUTRAL	0.0409	28481359
ALK	427	COSM6976583,	central_nervous_system	glioma	p.T25I	Substitution - Missense	2:29920586-29920586,	NEUTRAL	0.03866	28481359
ALK	427	COSM6984694,	lung	carcinoma	p.E119*	Substitution - Nonsense	2:29920305-29920305,	NEUTRAL	0.03838	28481359
ALK	427	COSM6911615,	large_intestine	carcinoma	p.R28C	Substitution - Missense	2:29920578-29920578,	NEUTRAL	0.03788	28481359
ALK	427	COSM1690374,	skin	malignant_melanoma	p.E668K	Substitution - Missense	2:29275138-29275138,	NEUTRAL	0.03685	28481359
ALK	427	COSM1690374,	skin	carcinoma	p.E668K	Substitution - Missense	2:29275138-29275138,	NEUTRAL	0.03685	25589618
ALK	427	COSM1690374,	skin	malignant_melanoma	p.E668K	Substitution - Missense	2:29275138-29275138,	NEUTRAL	0.03685	28481359
ALK	427	COSM1690374,	skin	carcinoma	p.E668K	Substitution - Missense	2:29275138-29275138,	NEUTRAL	0.03685	28481359
ALK	427	COSM6931621,	central_nervous_system	glioma	p.G159E	Substitution - Missense	2:29920184-29920184,	NEUTRAL	0.03325	28481359
ALK	427	COSM6928402,	urinary_tract	carcinoma	p.G2E	Substitution - Missense	2:29920655-29920655,	NEUTRAL	0.0332	28481359
ALK	427	COSM6911656,	lung	carcinoma	p.K665T	Substitution - Missense	2:29275146-29275146,	NEUTRAL	0.03223	28481359
ALK	427	COSM5607759,	skin	malignant_melanoma	p.D282N	Substitution - Missense	2:29694958-29694958,	NEUTRAL	0.03215	26343386
ALK	427	COSM5607759,	lung	carcinoma	p.D282N	Substitution - Missense	2:29694958-29694958,	NEUTRAL	0.03215	28481359
ALK	427	COSM6960584,	lung	carcinoma	p.A3S	Substitution - Missense	2:29920653-29920653,	NEUTRAL	0.03165	28481359
ALK	427	COSM6946663,	lung	carcinoma	p.G113C	Substitution - Missense	2:29920323-29920323,	NEUTRAL	0.03067	28481359
ALK	427	COSM6984318,	endometrium	carcinoma	p.N232S	Substitution - Missense	2:29717670-29717670,	NEUTRAL	0.02817	28481359
ALK	427	COSM6965037,	soft_tissue	angiosarcoma	p.S77F	Substitution - Missense	2:29920430-29920430,	NEUTRAL	0.02764	28481359
ALK	427	COSM28496,	autonomic_ganglia	neuroblastoma	p.?	Unknown	2:29222326-29222326,	NEUTRAL	0.02761	18990089
ALK	427	COSM28496,	autonomic_ganglia	neuroblastoma	p.?	Unknown	2:29222326-29222326,	NEUTRAL	0.02761	18990089
ALK	427	COSM28496,	autonomic_ganglia	neuroblastoma	p.?	Unknown	2:29222326-29222326,	NEUTRAL	0.02761	18990089
ALK	427	COSM28496,	autonomic_ganglia	neuroblastoma	p.?	Unknown	2:29222326-29222326,	NEUTRAL	0.02761	18990089
ALK	427	COSM28496,	autonomic_ganglia	neuroblastoma	p.?	Unknown	2:29222326-29222326,	NEUTRAL	0.02761	18990089
ALK	427	COSM6959900,	large_intestine	carcinoma	p.A29V	Substitution - Missense	2:29920574-29920574,	NEUTRAL	0.02616	28481359
ALK	427	COSM4751917,	large_intestine	carcinoma	p.R292H	Substitution - Missense	2:29694927-29694927,	NEUTRAL	0.02525	28481359
ALK	427	COSM6972526,	lung	carcinoma	p.V1465A	Substitution - Missense	2:29193693-29193693,	NEUTRAL	0.02488	28481359
ALK	427	COSM6952669,	upper_aerodigestive_tract	carcinoma	p.A112T	Substitution - Missense	2:29920326-29920326,	NEUTRAL	0.02396	28481359
ALK	427	COSM2941447,	skin	malignant_melanoma	p.S1487S	Substitution - coding silent	2:29193626-29193626,	NEUTRAL	0.02352	26343386
ALK	427	COSM6854509,	large_intestine	other	p.P671S	Substitution - Missense	2:29275129-29275129,	NEUTRAL	0.0188	28524162
ALK	427	COSM6854509,	large_intestine	other	p.P671S	Substitution - Missense	2:29275129-29275129,	NEUTRAL	0.0188	28524162
ALK	427	COSM6854509,	large_intestine	other	p.P671S	Substitution - Missense	2:29275129-29275129,	NEUTRAL	0.0188	28524162
ALK	427	COSM6909112,	oesophagus	carcinoma	p.L283P	Substitution - Missense	2:29694954-29694954,	NEUTRAL	0.01846	28481359
ALK	427	COSM95760,	lung	carcinoma	p.L283L	Substitution - coding silent	2:29694953-29694953,	NEUTRAL	0.01747	20668451
ALK	427	COSM6914203,	stomach	carcinoma	p.L165M	Substitution - Missense	2:29920167-29920167,	NEUTRAL	0.01695	28481359
ALK	427	COSM6914203,	stomach	carcinoma	p.L165M	Substitution - Missense	2:29920167-29920167,	NEUTRAL	0.01695	28481359
ALK	427	COSM6191381,	urinary_tract	carcinoma	p.G667E	Substitution - Missense	2:29275140-29275140,	NEUTRAL	0.01626	28348108
ALK	427	COSM1182534,	small_intestine	carcinoma	p.R179H	Substitution - Missense	2:29920124-29920124,	NEUTRAL	0.01576	28481359
ALK	427	COSM1182534,	breast	carcinoma	p.R179H	Substitution - Missense	2:29920124-29920124,	NEUTRAL	0.01576	28481359
ALK	427	COSM3580991,	NS	carcinoma	p.S670L	Substitution - Missense	2:29275131-29275131,	NEUTRAL	0.01514	28481359
ALK	427	COSM148824,	soft_tissue	haemangioblastoma	p.T1012T	Substitution - coding silent	2:29226953-29226953,	NEUTRAL	0.01274	25589003
ALK	427	COSM148824,	soft_tissue	haemangioblastoma	p.T1012T	Substitution - coding silent	2:29226953-29226953,	NEUTRAL	0.01274	25589003
ALK	427	COSM148824,	soft_tissue	haemangioblastoma	p.T1012T	Substitution - coding silent	2:29226953-29226953,	NEUTRAL	0.01274	25589003
ALK	427	COSM148824,	soft_tissue	haemangioblastoma	p.T1012T	Substitution - coding silent	2:29226953-29226953,	NEUTRAL	0.01274	25589003
ALK	427	COSM148824,	soft_tissue	haemangioblastoma	p.T1012T	Substitution - coding silent	2:29226953-29226953,	NEUTRAL	0.01274	25589003
ALK	427	COSM1236664,	autonomic_ganglia	neuroblastoma	p.R311H	Substitution - Missense	2:29694870-29694870,	NEUTRAL	0.00423	23202128
ALK	427	COSM6963013,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T1457A	Substitution - Missense	2:29193718-29193718,	NEUTRAL	0.0042	28481359
ALK	427	COSM6976100,	lung	carcinoma	p.R1436H	Substitution - Missense	2:29193780-29193780,	NEUTRAL	0.00319	28481359
ALK	427	COSM88796, COSM88797, COSM96492, COSM96493, COSM96494, COSM96495, COSM96496,	autonomic_ganglia	neuroblastoma	p.D1091N, p.F1174?, p.F1174L, p.R1231Q, p.R1275?, p.R1275Q, p.Y1278S	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	20719933
ALK	427	COSM88796, COSM88797,	autonomic_ganglia	neuroblastoma	p.F1174L, p.R1275Q	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	21625996
ALK	427	COSM143843,	soft_tissue	rhabdomyosarcoma	p.D1249fs*35	Deletion - Frameshift	2:29209876-29209877,	Info_not_available	Info_not_available	22184391
ALK	427	COSM255212, COSM88796, COSM88797,	autonomic_ganglia	ganglioneuroblastoma, neuroblastoma	p.F1174L, p.F1245I, p.R1275Q	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	22203052
ALK	427	COSM144252,	lung	carcinoma	p.T1151_L1152insT	Insertion - In frame	2:29222405-29222406,	Info_not_available	Info_not_available	22277784
ALK	427	COSM1169448,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.I1171N	Substitution - Missense	2:29222346-29222347,	Info_not_available	Info_not_available	23239810
ALK	427	COSM4169861,	autonomic_ganglia	neuroblastoma	p.F1174I	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	23669722
ALK	427	COSM4172514,	skin	malignant_melanoma	p.L1031fs*?	Frameshift	Info_not_available	Info_not_available	Info_not_available	24628946
ALK	427	COSM4422786, COSM4422787, COSM4422788, COSM4422789, COSM4422790, COSM4422791,	lung	carcinoma	p.F1174C, p.F1174V, p.G1202R, p.G1269A, p.L1196M, p.S1206Y	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	24675041
ALK	427	COSM4127677,	bone	chordoma	p.A877S	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	24983247
ALK	427	COSM88796,	autonomic_ganglia	neuroblastic_tumour, neuroblastoma	p.F1174L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25188507
ALK	427	COSM5417527,	endometrium	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	25233892
ALK	427	COSM6856659,	large_intestine	carcinoma	p.V1471L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25589621
ALK	427	COSM88796,	skin	carcinoma	p.F1174L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25724524
ALK	427	COSM4169861, COSM6024549,	NS	carcinoma	p.F1174I, p.R1214C	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26182302
ALK	427	COSM4422791, COSM5352215,	lung	carcinoma	p.F1174V, p.I1171S	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26464158
ALK	427	COSM5546635,	breast	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	26527317
ALK	427	COSM5981982,	lung	carcinoma	p.R1192G	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26826182
ALK	427	COSM5985119,	salivary_gland	carcinoma	p.S1206F	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27103403
ALK	427	COSM5546635, COSM5881426,	endometrium	carcinoma	p.?, p.Q459R	Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	27170661
ALK	427	COSM5885288,	large_intestine	carcinoma	p.A1200V	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27245685
ALK	427	COSM5945633,	central_nervous_system	glioma	p.P32A	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27425854
ALK	427	COSM5991608,	lung	carcinoma	p.V1180L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27877056
ALK	427	COSM7335205,	soft_tissue	liposarcoma	p.R311H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28177947
ALK	427	COSM6904389,	upper_aerodigestive_tract	carcinoma	p.V827I	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28493366
ALK	427	COSM7002298,	skin	malignant_melanoma	p.G1201R	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28870692
ALK	427	COSM6906043,	urinary_tract	carcinoma	p.P1153H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28945843
ALK	427	COSM6995433,	ovary	germ_cell_tumour	p.L54Gfs*3	Deletion - Frameshift	Info_not_available	Info_not_available	Info_not_available	28954785
ALK	427	COSM6856689,	thyroid	carcinoma	p.I407L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	29144541
ALK	427	COSM6997551,	liver	carcinoma	p.R1347Q	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	29487225
ALK	427	COSM95758,	lung	carcinoma	p.L449L	Substitution - coding silent	2:29328417-29328417,	Info_not_available	0.65543	20668451
ALK	427	COSM4991729, COSM5611218, COSM5611219,	skin	malignant_melanoma	p.E862E, p.G1137K, p.Q1134*	Substitution - Missense, Substitution - Nonsense, Substitution - coding silent	2:29222557-29222558, 2:29222567-29222568, 2:29232350-29232350,	Info_not_available	0.60254, Info_not_available	26343386
ALK	427	COSM4991729, COSM4991730, COSM4991732,	skin	carcinoma	p.E862E, p.I805I, p.P431S	Substitution - Missense, Substitution - coding silent	2:29232350-29232350, 2:29233637-29233637, 2:29328473-29328473,	Info_not_available	0.55332, .60254, .65414	25589618
ALK	427	COSM4771397,	breast	carcinoma	p.Q1428*	Substitution - Nonsense	2:29193805-29193805,	Info_not_available	0.54944	24185512
ALK	427	COSM5019786,	soft_tissue	haemangioblastoma	p.T1446T	Substitution - coding silent	2:29193749-29193749,	Info_not_available	0.53735	25589003
ALK	427	COSM12786,	lung	carcinoma	p.Y262Y	Substitution - coding silent	2:29717579-29717579,	Info_not_available	0.52709	16140923
ALK	427	COSM1244833, COSM2941487, COSM2941491, COSM2941501, COSM3581009, COSM4526739, COSM4553889, COSM6909965, COSM6911335, COSM6911553, COSM6913328, COSM6919739, COSM6922292, COSM6922544, COSM6923647, COSM6926372, COSM6927728, COSM6934200, COSM6936019, COSM6936136, COSM6938328, COSM6940013, COSM6940767, COSM6945222, COSM6946085, COSM6947853, COSM6949692, COSM6950711, COSM6958639, COSM6962066, COSM6964302, COSM6968757, COSM6969312, COSM6969593, COSM6971334, COSM6971842, COSM6972843, COSM6973035, COSM6974061, COSM6974136, COSM6977322, COSM6978082, COSM6981086, COSM6982181, COSM6984027, COSM6986566,	NS, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, kidney, large_intestine, lung, pancreas, prostate, skin, small_intestine, stomach, urinary_tract	carcinoid-endocrine_tumour, carcinoma, glioma, lymphoid_neoplasm, malignant_melanoma	p.A161V, p.A161fs*25, p.A462D, p.C928fs*11, p.D1203fs*82, p.D239G, p.D508N, p.D732N, p.E160fs*26, p.E182K, p.E314D, p.E663V, p.E804D, p.G1202fs*56, p.G1474fs*3, p.G202R, p.G432N, p.G574M, p.G616fs*49, p.G618E, p.G822fs*9, p.G893K, p.H904Q, p.I801M, p.K1454N, p.K1525delK, p.K1610R, p.L449_Q450>H*, p.L838fs*27, p.M301I, p.N1115fs*18, p.P1551S, p.P43S, p.Q167L, p.Q515*, p.R133L, p.R200K, p.R214fs*35, p.R41L, p.R472Q, p.R809K, p.S295F, p.S536fs*25, p.T535I, p.T901A, p.V142M	Complex - compound substitution, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Substitution - Missense, Substitution - Nonsense	2:29193258-29193258, 2:29193436-29193436, 2:29193512-29193514, 2:29193666-29193666, 2:29193725-29193725, 2:29220745-29220746, 2:29220746-29220746, 2:29223356-29223357, 2:29228918-29228918, 2:29228987-29228987, 2:29228998-29228998, 2:29229021-29229022, 2:29232423-29232424, 2:29233587-29233587, 2:29233626-29233626, 2:29233640-29233640, 2:29233649-29233649, 2:29251115-29251115, 2:29275152-29275152, 2:29275461-29275461, 2:29275467-29275467, 2:29296984-29296985, 2:29318346-29318346, 2:29318346-29318347, 2:29320754-29320754, 2:29320775-29320775, 2:29320882-29320882, 2:29328379-29328379, 2:29328416-29328418, 2:29328469-29328470, 2:29694860-29694860, 2:29694899-29694899, 2:29694918-29694918, 2:29717649-29717649, 2:29920020-29920020, 2:29920056-29920056, 2:29920061-29920061, 2:29920116-29920116, 2:29920160-29920160, 2:29920178-29920178, 2:29920179-29920179, 2:29920186-29920186, 2:29920236-29920236, 2:29920262-29920262, 2:29920533-29920533, 2:29920538-29920538,	Info_not_available	0.5152, .51593, .532, .53538, .54102, .549, .57701, .57917, .58517, .591, .60383, .60803, .60814, .61003, .6123, .61999, .6273, .64127, .6422, .64787, .64949, .65683, .66252, .66684, .67375, .68071, .68116, .69513, Info_not_available	28481359