Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases AP2A2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, tandem affinity purification association, physical 19380743, 24189400, 8617812 0.53 BioGRID, IntAct AP2B1 Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct AP2M1 Affinity Capture-MS, tandem affinity purification association, physical 19380743, 24189400 0.53 BioGRID, IntAct APP Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, pull down physical, physical association 11877420, 12485888 0.59 BioGRID, IntAct, MINT AR fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct ARHGEF5 Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, tandem affinity purification association, physical 24189400 0.46 BioGRID, IntAct BUB1 two hybrid array physical association 24412244 0.37 IntAct, MINT CAD tandem affinity purification association 19380743 0.35 IntAct CALCOCO2 Two-hybrid, two hybrid pooling approach physical, physical association 16189514 0.37 BioGRID, IntAct CBL Affinity Capture-MS, Affinity Capture-Western, coimmunoprecipitation, pull down, tandem affinity purification association, physical, physical association 10025673, 10570290, 15677445, 19380743, 8621719, 8662998, 8950973, 9434624, 9461587, 9541596 0.77 BioGRID, IntAct, MINT CBLC Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT CD247 nuclear magnetic resonance association 7544002 0.35 IntAct, MINT CD3E pull down association 11855827 0.35 IntAct, MINT CDC5L Affinity Capture-MS, anti bait coimmunoprecipitation association, physical 20467437 0.35 BioGRID, IntAct, MINT CDH5 Affinity Capture-Western, coimmunoprecipitation, pull down direct interaction, physical, physical association 11950700 0.54 BioGRID, IntAct, MINT CEACAM1 pull down association 11694516 0.35 IntAct, MINT CEP170 Proximity Label-MS, proximity-dependent biotin identification association, physical 26638075 0.35 BioGRID, IntAct CRK Affinity Capture-MS, Affinity Capture-Western, proximity ligation assay, tandem affinity purification association, physical, physical association 10464310, 19380743, 23397142, 9617486 0.56 BioGRID, IntAct CSF2RB Affinity Capture-Western, coimmunoprecipitation, pull down association, physical 10704825, 16437163 0.53 BioGRID, IntAct, MINT CSK Affinity Capture-MS, Reconstituted Complex, tandem affinity purification association, physical 12048194, 19380743 0.35 BioGRID, IntAct DDR2 Affinity Capture-Western, Two-hybrid, coimmunoprecipitation, two hybrid physical, physical association 11884411 0.51 BioGRID, IntAct, MINT DNAJA2 Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct DNM2 Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct DUSP23 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT EGFR Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, PCA, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, competition binding, experimental interaction detection, luminescence based mammalian interactome mapping, protein array, protein kinase assay, pull down, tandem affinity purification, ubiquitin reconstruction, x-ray crystallography association, direct interaction, phosphorylation reaction, physical, physical association 10049786, 10595738, 10635327, 10766863, 11370743, 11408594, 15657067, 16273093, 16729043, 18271526, 19531499, 20473329, 20935677, 21278788, 23178716, 23799367, 23956138, 24189400, 24430869, 24658140, 24797263, 25402006, 26551075, 28065597, 7506413, 7518560, 7542744, 8034616, 8662998, 8810340, 9130710, 9544989, 9756944 0.58, 0.97 BioGRID, IntAct, MINT ELP1 tandem affinity purification association 19380743 0.35 IntAct ERBB2 Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Two-hybrid, protein array, pull down, ubiquitin reconstruction association, direct interaction, physical, physical association 10085134, 16273093, 16729043, 16843263, 24658140, 28065597, 9710588, 9756944 0.37, 0.70 BioGRID, IntAct, MINT ERBB3 Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, protein array, pull down, tandem affinity purification, ubiquitin reconstruction association, direct interaction, physical, physical association 11546794, 16273093, 16729043, 24189400, 24658140, 9756944 0.37, 0.70 BioGRID, IntAct, MINT ERBB4 Affinity Capture-MS, Protein-peptide, protein array, pull down, ubiquitin reconstruction direct interaction, physical, physical association 16273093, 16729043, 24658140 0.37, 0.61 BioGRID, IntAct, MINT ERRFI1 Affinity Capture-MS, tandem affinity purification association, physical 24189400 0.35 BioGRID, IntAct ESR1 Affinity Capture-Western, Reconstituted Complex, anti tag coimmunoprecipitation physical, physical association 11773443, 20935677 0.40 BioGRID, IntAct EZR proximity-dependent biotin identification association 29568061 0.35 IntAct FAM118B Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT FASTKD3 tandem affinity purification association 20869947 0.35 IntAct FBXW7 two hybrid array physical association 24412244 0.37 IntAct, MINT FCGR1A experimental interaction detection phosphorylation reaction 9716598 0.31 IntAct, MINT FCGR2B Affinity Capture-Western, pull down association, physical 10382761, 8940017 0.35 BioGRID, IntAct, MINT FYN pull down direct interaction 7516469 0.44 IntAct, MINT GAB1 Affinity Capture-Western, Far Western, fluorescence polarization spectroscopy direct interaction, physical 14982882, 24728074, 9804835 0.44 BioGRID, IntAct GAB2 Affinity Capture-Western, coimmunoprecipitation, pull down direct interaction, physical, physical association 10704825, 11782427, 12135708, 14982882 0.54 BioGRID, IntAct, MINT GEMIN7 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT GRAP pull down association 8995379 0.35 IntAct, MINT GRB2 Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Protein-peptide, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, bimolecular fluorescence complementation, coimmunoprecipitation, isothermal titration calorimetry, pull down, surface plasmon resonance, tandem affinity purification, x-ray crystallography association, direct interaction, physical, physical association 10049786, 10080542, 10477741, 10570290, 11302736, 11370743, 11505033, 11792427, 11827484, 11964172, 12149229, 12213123, 12441060, 12485888, 12577067, 12898421, 15688026, 15812354, 16371368, 16520382, 19380743, 21706016, 21725358, 22974441, 23178716, 24189400, 24430869, 25416956, 26551075, 7514169, 7524086, 7535773, 7537740, 7559490, 7650032, 8112292, 8195171, 8294403, 8491186, 8621719, 8647288, 8662733, 8662998, 8663178, 8810340, 8939605, 8940013, 8950973, 8995379, 9032244, 9045692, 9083103, 9126968, 9129019, 9175774, 9254595, 9434624, 9541596, 9544989, 9886492, 9927207 0.40, 0.52, 0.97 BioGRID, IntAct, MINT HMOX2 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT HNRNPA2B1 Affinity Capture-MS, tandem affinity purification association, physical 24189400 0.35 BioGRID, IntAct IGF1R Affinity Capture-Western, Two-hybrid, far western blotting, two hybrid physical, physical association 14764897, 15629149, 16113100, 24051437, 7541045, 7559507, 8776723 0.37, 0.51 BioGRID, IntAct ILK Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT INPP5D Affinity Capture-Western, pull down direct interaction, physical 10194451, 10704825, 10822173, 10900203, 12024011, 12149229, 15470047, 8643691 0.44 BioGRID, IntAct, MINT INPPL1 Affinity Capture-MS, Affinity Capture-Western, tandem affinity purification association, physical 10194451, 11349134, 19380743, 9660833 0.35 BioGRID, IntAct INSR Reconstituted Complex, Two-hybrid, pull down, two hybrid physical, physical association 10803466, 15629149, 7499194, 9593725 0.57 BioGRID, IntAct, MINT IQGAP1 Affinity Capture-MS, fluorescence microscopy colocalization, physical 19380743, 20075861 0.27 BioGRID, IntAct, MINT KDR Affinity Capture-Western, coimmunoprecipitation, pull down association, physical, physical association 10319320, 11950700, 12214271 0.56 BioGRID, IntAct, MINT KIT fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct KRT18 fluorescence microscopy colocalization 12577067 0.27 IntAct LCP2 Affinity Capture-Western, coimmunoprecipitation physical, physical association 9716598 0.40 BioGRID, IntAct, MINT LRRK1 anti tag coimmunoprecipitation association 24947832 0.35 IntAct LYN Affinity Capture-Western, pull down direct interaction, physical 7516469, 7650013 0.44 BioGRID, IntAct, MINT MAPK1 Affinity Capture-Western, fluorescent resonance energy transfer, isothermal titration calorimetry, pull down, x ray scattering direct interaction, physical, physical association 10996427, 23584453 0.40, 0.62 BioGRID, IntAct MAPK6 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT MET Affinity Capture-Western, fluorescence polarization spectroscopy direct interaction, physical 24728074, 9660480 0.44 BioGRID, IntAct MRPL44 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT MYH9 Affinity Capture-MS, tandem affinity purification association, physical 19380743, 24189400 0.35 BioGRID, IntAct MYO1C Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct MYO1D Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct NTRK1 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, competition binding association, physical 10092678, 10708759, 12446789, 25921289, 8183561, 8226808, 9856458 0.46 BioGRID, IntAct, MINT NUDT21 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT OSGEP two hybrid physical association 21900206 0.37 IntAct, MINT PIK3R1 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, proximity ligation assay, pull down, tandem affinity purification association, physical, physical association 16135792, 16219545, 19380743, 19889638, 23397142, 7537361, 8621719, 8662998, 9541596 0.83 BioGRID, IntAct, MINT PIK3R2 Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct PPP1R9B Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct PRKCD Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, tandem affinity purification association, physical 12024011, 19380743 0.35 BioGRID, IntAct PRKRA Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT PRSS3 Affinity Capture-MS, tandem affinity purification association, physical 24189400 0.35 BioGRID, IntAct PSTPIP2 Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct PTPN12 Affinity Capture-MS, Affinity Capture-Western, Proximity Label-MS, Reconstituted Complex, Two-hybrid, tandem affinity purification, two hybrid array association, physical, physical association 19380743, 24189400, 24412244, 27880917, 28514442, 7929214, 8626541 0.66 BioGRID, IntAct, MINT RB1 two hybrid array physical association 24412244 0.37 IntAct, MINT RET Affinity Capture-Western, Reconstituted Complex, pull down physical, physical association 15677445, 8183561, 9047384 0.40 BioGRID, IntAct, MINT S100A8 Affinity Capture-MS, tandem affinity purification association, physical 19380743, 24189400 0.35 BioGRID, IntAct S100A9 Affinity Capture-MS, tandem affinity purification association, physical 19380743, 24189400 0.35 BioGRID, IntAct SCLT1 Proximity Label-MS, proximity-dependent biotin identification association, physical 26638075 0.35 BioGRID, IntAct SEC16A Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct SHC1 Affinity Capture-MS, tandem affinity purification association, physical 19380743, 24189400 0.35 BioGRID, IntAct SIRT4 {ECO:0000255|HAMAP-Rule:MF_03161, anti tag coimmunoprecipitation association 25525879 0.35 IntAct SMAD4 two hybrid array physical association 24412244 0.37 IntAct, MINT SMAP two hybrid physical association 21900206 0.37 IntAct, MINT SOS1 Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, tandem affinity purification association, physical, physical association 10025673, 10570290, 10675333, 10783152, 16371368, 19380743, 7559490, 8950973, 9344843, 9544989 0.56 BioGRID, IntAct, MINT SPTA1 Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct SRC protein kinase assay phosphorylation reaction 26551075 0.44 IntAct STAT5A Affinity Capture-Western, proximity ligation assay physical, physical association 10996427, 23397142 0.40 BioGRID, IntAct SUV39H2 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT TEK coimmunoprecipitation, pull down association 14665640 0.46 IntAct, MINT TGFBR2 coimmunoprecipitation association 17440088 0.35 IntAct, MINT UBASH3B Affinity Capture-MS, tandem affinity purification association, physical 19380743, 24189400 0.53 BioGRID, IntAct USP9X Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct USP9Y Affinity Capture-MS, tandem affinity purification association, physical 19380743 0.35 BioGRID, IntAct YWHAZ coimmunoprecipitation association 11342545, 19218246 0.53 IntAct, MINT ZAP70 Affinity Capture-Western, Biochemical Activity, anti tag coimmunoprecipitation physical, physical association 15688026, 23267066, 9685404 0.40 BioGRID, IntAct, MINT