Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
RB1	9884	COSM4990385,	oesophagus	carcinoma	p.?	Unknown	13:48463836-48463836,	PATHOGENIC	0.99839	28481359
RB1	9884	COSM4990385,	central_nervous_system	glioma	p.?	Unknown	13:48463836-48463836,	PATHOGENIC	0.99839	28481359
RB1	9884	COSM4990385,	skin	carcinoma	p.?	Unknown	13:48463836-48463836,	PATHOGENIC	0.99839	25589618
RB1	9884	COSM940,	ovary	carcinoma	p.K715*	Substitution - Nonsense	13:48463767-48463767,	PATHOGENIC	0.99817	25846456
RB1	9884	COSM940,	prostate	carcinoma	p.K715*	Substitution - Nonsense	13:48463767-48463767,	PATHOGENIC	0.99817	1986144
RB1	9884	COSM940,	prostate	carcinoma	p.K715*	Substitution - Nonsense	13:48463767-48463767,	PATHOGENIC	0.99817	2300823
RB1	9884	COSM5945307,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K729E	Substitution - Missense	13:48463809-48463809,	PATHOGENIC	0.99813	27276561
RB1	9884	COSM40941,	central_nervous_system	glioma	p.Y728C	Substitution - Missense	13:48463807-48463807,	PATHOGENIC	0.99813	18772396
RB1	9884	COSM926,	ovary	carcinoma	p.M704V	Substitution - Missense	13:48463734-48463734,	PATHOGENIC	0.99792	9194486
RB1	9884	COSM1042,	urinary_tract	carcinoma	p.?	Unknown	13:48463729-48463729,	PATHOGENIC	0.99783	2521957
RB1	9884	COSM1042,	urinary_tract	carcinoma	p.?	Unknown	13:48463729-48463729,	PATHOGENIC	0.99783	2594029
RB1	9884	COSM1942416,	lung	carcinoma	p.?	Unknown	13:48463730-48463730,	PATHOGENIC	0.99758	28481359
RB1	9884	COSM6906487,	urinary_tract	carcinoma	p.I724S	Substitution - Missense	13:48463795-48463795,	PATHOGENIC	0.99758	29420467
RB1	9884	COSM1942416,	breast	carcinoma	p.?	Unknown	13:48463730-48463730,	PATHOGENIC	0.99758	28685160
RB1	9884	COSM1942416,	upper_aerodigestive_tract	carcinoma	p.?	Unknown	13:48463730-48463730,	PATHOGENIC	0.99758	28581676
RB1	9884	COSM6950672,	pancreas	carcinoma	p.?	Unknown	13:48463837-48463837,	PATHOGENIC	0.99756	28481359
RB1	9884	COSM254912,	urinary_tract	carcinoma	p.I724N	Substitution - Missense	13:48463795-48463795,	PATHOGENIC	0.99755	21822268
RB1	9884	COSM5700369,	eye	retinoblastoma	p.Q736*	Substitution - Nonsense	13:48463830-48463830,	PATHOGENIC	0.99747	28481359
RB1	9884	COSM5700369,	upper_aerodigestive_tract	carcinoma	p.Q736*	Substitution - Nonsense	13:48463830-48463830,	PATHOGENIC	0.99747	28481359
RB1	9884	COSM5700369,	urinary_tract	carcinoma	p.Q736*	Substitution - Nonsense	13:48463830-48463830,	PATHOGENIC	0.99747	28481359
RB1	9884	COSM29529,	skin	carcinoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	28481359
RB1	9884	COSM29529,	urinary_tract	carcinoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	28481359
RB1	9884	COSM29529,	urinary_tract	carcinoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	29420467
RB1	9884	COSM29529,	endometrium	carcinoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	28481359
RB1	9884	COSM29529,	breast	carcinoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	28481359
RB1	9884	COSM29529,	skin	malignant_melanoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	18677770
RB1	9884	COSM29529,	lung	carcinoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	28481359
RB1	9884	COSM29529,	salivary_gland	carcinoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	27334835
RB1	9884	COSM29529,	lung	carcinoma	p.Q471*	Substitution - Nonsense	13:48380074-48380074,	PATHOGENIC	0.9973	28481359
RB1	9884	COSM5700986,	lung	carcinoma	p.E837*	Substitution - Nonsense	13:48473379-48473379,	PATHOGENIC	0.99723	26168399
RB1	9884	COSM5693393,	urinary_tract	carcinoma	p.?	Unknown	13:48473391-48473391,	PATHOGENIC	0.99723	28481359
RB1	9884	COSM5610463,	skin	malignant_melanoma	p.G840V	Substitution - Missense	13:48473389-48473389,	PATHOGENIC	0.99723	26343386
RB1	9884	COSM882,	eye	retinoblastoma	p.D718N	Substitution - Missense	13:48463776-48463776,	PATHOGENIC	0.99719	12402348
RB1	9884	COSM6979514,	endometrium	carcinoma	p.I711T	Substitution - Missense	13:48463756-48463756,	PATHOGENIC	0.99698	28481359
RB1	9884	COSM254916,	urinary_tract	carcinoma	p.?	Unknown	13:48381444-48381444,	PATHOGENIC	0.99689	21822268
RB1	9884	COSM13739,	central_nervous_system	glioma	p.?	Unknown	13:48473391-48473391,	PATHOGENIC	0.99685	28481359
RB1	9884	COSM6921040,	skin	malignant_melanoma	p.?	Unknown	13:48473359-48473359,	PATHOGENIC	0.99685	28481359
RB1	9884	COSM6921040,	urinary_tract	carcinoma	p.?	Unknown	13:48473359-48473359,	PATHOGENIC	0.99685	28481359
RB1	9884	COSM13739,	lung	carcinoma	p.?	Unknown	13:48473391-48473391,	PATHOGENIC	0.99685	28481359
RB1	9884	COSM6942570,	urinary_tract	carcinoma	p.?	Unknown	13:48473358-48473358,	PATHOGENIC	0.99657	28481359
RB1	9884	COSM6942570,	urinary_tract	carcinoma	p.?	Unknown	13:48473358-48473358,	PATHOGENIC	0.99657	28481359
RB1	9884	COSM6942570,	urinary_tract	carcinoma	p.?	Unknown	13:48473358-48473358,	PATHOGENIC	0.99657	28481359
RB1	9884	COSM49011,	urinary_tract	carcinoma	p.?	Unknown	13:48463730-48463730,	PATHOGENIC	0.99648	28481359
RB1	9884	COSM49011,	lung	carcinoma	p.?	Unknown	13:48463730-48463730,	PATHOGENIC	0.99648	18948947
RB1	9884	COSM6922951,	skin	malignant_melanoma	p.Y454C	Substitution - Missense	13:48379622-48379622,	PATHOGENIC	0.99637	28481359
RB1	9884	COSM254911,	urinary_tract	carcinoma	p.?	Unknown	13:48465369-48465369,	PATHOGENIC	0.99591	21822268
RB1	9884	COSM1942322,	urinary_tract	carcinoma	p.Q444L	Substitution - Missense	13:48377033-48377033,	PATHOGENIC	0.99591	28481359
RB1	9884	COSM5546624,	breast	carcinoma	p.M457R	Substitution - Missense	13:48379631-48379631,	PATHOGENIC	0.9957	26527317
RB1	9884	COSM5546624,	breast	carcinoma	p.M457R	Substitution - Missense	13:48379631-48379631,	PATHOGENIC	0.9957	26527317
RB1	9884	COSM23825,	lung	carcinoma	p.S834*	Substitution - Nonsense	13:48473371-48473371,	PATHOGENIC	0.99566	28481359
RB1	9884	COSM23825,	urinary_tract	carcinoma	p.S834*	Substitution - Nonsense	13:48473371-48473371,	PATHOGENIC	0.99566	28481359
RB1	9884	COSM1942320,	soft_tissue	leiomyosarcoma	p.Q444R	Substitution - Missense	13:48377033-48377033,	PATHOGENIC	0.99559	28481359
RB1	9884	COSM6950973,	breast	carcinoma	p.S838*	Substitution - Nonsense	13:48473383-48473383,	PATHOGENIC	0.99553	28481359
RB1	9884	COSM6936009,	skin	carcinoma	p.E465*	Substitution - Nonsense	13:48380056-48380056,	PATHOGENIC	0.9955	28481359
RB1	9884	COSM6957971,	lung	carcinoma	p.L832*	Substitution - Nonsense	13:48473365-48473365,	PATHOGENIC	0.9953	28481359
RB1	9884	COSM5677124,	upper_aerodigestive_tract	carcinoma	p.?	Unknown	13:48465369-48465369,	PATHOGENIC	0.99515	28493366
RB1	9884	COSM5677124,	central_nervous_system	glioma	p.?	Unknown	13:48465369-48465369,	PATHOGENIC	0.99515	28481359
RB1	9884	COSM3469150,	skin	adnexal_tumour	p.L461P	Substitution - Missense	13:48379643-48379643,	PATHOGENIC	0.99495	27311873
RB1	9884	COSM6191615,	large_intestine	carcinoma	p.D730V	Substitution - Missense	13:48463813-48463813,	PATHOGENIC	0.99475	25617745
RB1	9884	COSM6950929,	lung	carcinoma	p.?	Unknown	13:48381445-48381445,	PATHOGENIC	0.99448	28481359
RB1	9884	COSM35350,	lung	carcinoma	p.?	Unknown	13:48459687-48459687,	PATHOGENIC	0.99427	28481359
RB1	9884	COSM1012,	lung	carcinoma	p.?	Unknown	13:48381445-48381445,	PATHOGENIC	0.99407	8302602
RB1	9884	COSM323002,	urinary_tract	carcinoma	p.S829*	Substitution - Nonsense	13:48465365-48465365,	PATHOGENIC	0.99398	28481359
RB1	9884	COSM1731418,	NS	carcinoma	p.E675*	Substitution - Nonsense	13:48459750-48459750,	PATHOGENIC	0.99377	28481359
RB1	9884	COSM5686463,	eye	retinoblastoma	p.Q631*	Substitution - Nonsense	13:48456280-48456280,	PATHOGENIC	0.99352	28481359
RB1	9884	COSM1030,	cervix	carcinoma	p.?	Unknown	13:48459687-48459687,	PATHOGENIC	0.9935	1648218
RB1	9884	COSM1030,	eye	retinoblastoma	p.?	Unknown	13:48459687-48459687,	PATHOGENIC	0.9935	22237022
RB1	9884	COSM932,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.Q444H	Substitution - Missense	13:48377034-48377034,	PATHOGENIC	0.99333	11103795
RB1	9884	COSM6005787,	skin	adnexal_tumour	p.E492Q	Substitution - Missense	13:48380217-48380217,	PATHOGENIC	0.9933	27287813
RB1	9884	COSM6005787,	skin	adnexal_tumour	p.E492Q	Substitution - Missense	13:48380217-48380217,	PATHOGENIC	0.9933	27287813
RB1	9884	COSM6005787,	skin	adnexal_tumour	p.E492Q	Substitution - Missense	13:48380217-48380217,	PATHOGENIC	0.9933	27287813
RB1	9884	COSM6005787,	skin	adnexal_tumour	p.E492Q	Substitution - Missense	13:48380217-48380217,	PATHOGENIC	0.9933	27287813
RB1	9884	COSM6921301,	soft_tissue	leiomyosarcoma	p.?	Unknown	13:48380242-48380242,	PATHOGENIC	0.99323	28481359
RB1	9884	COSM1013,	thyroid	adenoma-nodule-goitre	p.?	Unknown	13:48379651-48379651,	PATHOGENIC	0.99315	28481359
RB1	9884	COSM1013,	eye	retinoblastoma	p.?	Unknown	13:48379651-48379651,	PATHOGENIC	0.99315	12402348
RB1	9884	COSM3469156,	breast	other	p.?	Unknown	13:48459686-48459686,	PATHOGENIC	0.99305	26437033
RB1	9884	COSM6939092,	skin	malignant_melanoma	p.S829L	Substitution - Missense	13:48465365-48465365,	PATHOGENIC	0.99303	28481359
RB1	9884	COSM4428412,	NS	malignant_melanoma	p.R661Q	Substitution - Missense	13:48459709-48459709,	PATHOGENIC	0.99293	25148578
RB1	9884	COSM6953277,	urinary_tract	carcinoma	p.E492*	Substitution - Nonsense	13:48380217-48380217,	PATHOGENIC	0.99284	28481359
RB1	9884	COSM6953277,	urinary_tract	carcinoma	p.E492*	Substitution - Nonsense	13:48380217-48380217,	PATHOGENIC	0.99284	28481359
RB1	9884	COSM317961,	lung	carcinoma	p.?	Unknown	13:48379651-48379651,	PATHOGENIC	0.99284	22941188
RB1	9884	COSM6924392,	urinary_tract	carcinoma	p.?	Unknown	13:48456350-48456350,	PATHOGENIC	0.99281	28481359
RB1	9884	COSM6925473,	urinary_tract	carcinoma	p.?	Unknown	13:48380242-48380242,	PATHOGENIC	0.99276	28481359
RB1	9884	COSM6935466,	endometrium	carcinoma	p.K653T	Substitution - Missense	13:48456347-48456347,	PATHOGENIC	0.99263	28481359
RB1	9884	COSM5991648,	breast	carcinoma	p.?	Unknown	13:48380085-48380085,	PATHOGENIC	0.99252	25927147
RB1	9884	COSM5991648,	large_intestine	carcinoma	p.?	Unknown	13:48380085-48380085,	PATHOGENIC	0.99252	28481359
RB1	9884	COSM6981304,	lung	carcinoma	p.S459C	Substitution - Missense	13:48379637-48379637,	PATHOGENIC	0.99252	28481359
RB1	9884	COSM1942392,	central_nervous_system	glioma	p.K652*	Substitution - Nonsense	13:48456343-48456343,	PATHOGENIC	0.99242	28481359
RB1	9884	COSM6975589,	lung	carcinoma	p.?	Unknown	13:48459686-48459686,	PATHOGENIC	0.99231	28481359
RB1	9884	COSM326323,	lung	carcinoma	p.G435*	Substitution - Nonsense	13:48377005-48377005,	PATHOGENIC	0.9923	28481359
RB1	9884	COSM6931556,	breast	carcinoma	p.?	Unknown	13:48376917-48376917,	PATHOGENIC	0.9923	28481359
RB1	9884	COSM326323,	lung	carcinoma	p.G435*	Substitution - Nonsense	13:48377005-48377005,	PATHOGENIC	0.9923	28481359
RB1	9884	COSM6984014,	lung	carcinoma	p.?	Unknown	13:48380085-48380085,	PATHOGENIC	0.99211	28481359
RB1	9884	COSM6908838,	lung	carcinoma	p.?	Unknown	13:48380164-48380164,	PATHOGENIC	0.99171	28481359
RB1	9884	COSM1016,	eye	retinoblastoma	p.?	Unknown	13:48456350-48456350,	PATHOGENIC	0.99154	9311732
RB1	9884	COSM1016,	soft_tissue	leiomyosarcoma	p.?	Unknown	13:48456350-48456350,	PATHOGENIC	0.99154	28481359
RB1	9884	COSM317959,	lung	carcinoma	p.?	Unknown	13:48380163-48380163,	PATHOGENIC	0.99125	22941188
RB1	9884	COSM317959,	skin	carcinoma	p.?	Unknown	13:48380163-48380163,	PATHOGENIC	0.99125	28481359
RB1	9884	COSM3936346,	stomach	carcinoma	p.?	Unknown	13:48464997-48464997,	PATHOGENIC	0.99122	28481359
RB1	9884	COSM6954670,	lung	carcinoma	p.E737*	Substitution - Nonsense	13:48463833-48463833,	PATHOGENIC	0.99116	28481359
RB1	9884	COSM1041,	eye	retinoblastoma	p.?	Unknown	13:48367604-48367604,	PATHOGENIC	0.99101	2594029
RB1	9884	COSM14211,	prostate	carcinoma	p.?	Unknown	13:48376917-48376917,	PATHOGENIC	0.99096	28481359
RB1	9884	COSM14211,	lung	carcinoma	p.?	Unknown	13:48376917-48376917,	PATHOGENIC	0.99096	28481359
RB1	9884	COSM14211,	breast	carcinoma	p.?	Unknown	13:48376917-48376917,	PATHOGENIC	0.99096	28481359
RB1	9884	COSM3733492,	thyroid	carcinoma	p.L512*	Substitution - Nonsense	13:48381283-48381283,	PATHOGENIC	0.99064	28481359
RB1	9884	COSM3733492,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L512*	Substitution - Nonsense	13:48381283-48381283,	PATHOGENIC	0.99064	24682267
RB1	9884	COSM3733492,	central_nervous_system	glioma	p.L512*	Substitution - Nonsense	13:48381283-48381283,	PATHOGENIC	0.99064	28481359
RB1	9884	COSM1014,	eye	retinoblastoma	p.?	Unknown	13:48376916-48376916,	PATHOGENIC	0.9906	9311732
RB1	9884	COSM1014,	pancreas	carcinoma	p.?	Unknown	13:48376916-48376916,	PATHOGENIC	0.9906	22251937
RB1	9884	COSM13479,	lung	carcinoma	p.E440*	Substitution - Nonsense	13:48377020-48377020,	PATHOGENIC	0.99056	22941188
RB1	9884	COSM13479,	lung	carcinoma	p.E440*	Substitution - Nonsense	13:48377020-48377020,	PATHOGENIC	0.99056	18948947
RB1	9884	COSM6939785,	breast	carcinoma	p.S463*	Substitution - Nonsense	13:48379649-48379649,	PATHOGENIC	0.99051	28481359
RB1	9884	COSM1659143,	breast	carcinoma	p.E693*	Substitution - Nonsense	13:48459804-48459804,	PATHOGENIC	0.99045	23575477
RB1	9884	COSM1659143,	breast	carcinoma	p.E693*	Substitution - Nonsense	13:48459804-48459804,	PATHOGENIC	0.99045	23575477
RB1	9884	COSM317962,	eye	retinoblastoma	p.?	Unknown	13:48459834-48459834,	PATHOGENIC	0.99045	28481359
RB1	9884	COSM6924591,	lung	carcinoma	p.D701Y	Substitution - Missense	13:48459828-48459828,	PATHOGENIC	0.99045	28481359
RB1	9884	COSM6919084,	lung	carcinoma	p.W563C	Substitution - Missense	13:48381437-48381437,	PATHOGENIC	0.99022	28481359
RB1	9884	COSM1322863,	breast	carcinoma	p.A562P	Substitution - Missense	13:48381432-48381432,	PATHOGENIC	0.99022	28270497
RB1	9884	COSM6959291,	lung	carcinoma	p.?	Unknown	13:48465204-48465204,	PATHOGENIC	0.98983	28481359
RB1	9884	COSM6935464,	endometrium	carcinoma	p.S644Y	Substitution - Missense	13:48456320-48456320,	PATHOGENIC	0.98979	28481359
RB1	9884	COSM6972179,	NS	carcinoma	p.S501C	Substitution - Missense	13:48381249-48381249,	PATHOGENIC	0.9897	28481359
RB1	9884	COSM1034,	bone	osteosarcoma	p.?	Unknown	13:48381246-48381246,	PATHOGENIC	0.98966	9559293
RB1	9884	COSM1034,	bone	osteosarcoma	p.?	Unknown	13:48381246-48381246,	PATHOGENIC	0.98966	9559293
RB1	9884	COSM6927229,	breast	carcinoma	p.S565*	Substitution - Nonsense	13:48381442-48381442,	PATHOGENIC	0.98956	28481359
RB1	9884	COSM4990383,	skin	carcinoma	p.E737E	Substitution - coding silent	13:48463835-48463835,	PATHOGENIC	0.98952	25589618
RB1	9884	COSM865,	lung	carcinoma	p.H673P	Substitution - Missense	13:48459745-48459745,	PATHOGENIC	0.98932	8302602
RB1	9884	COSM947795,	breast	carcinoma	p.E545*	Substitution - Nonsense	13:48381381-48381381,	PATHOGENIC	0.98929	27284958
RB1	9884	COSM6925130,	lung	carcinoma	p.E551*	Substitution - Nonsense	13:48381399-48381399,	PATHOGENIC	0.98929	28481359
RB1	9884	COSM6906515,	NS	NS	p.E539*	Substitution - Nonsense	13:48381363-48381363,	PATHOGENIC	0.98929	29420467
RB1	9884	COSM13141,	breast	other	p.E533*	Substitution - Nonsense	13:48381345-48381345,	PATHOGENIC	0.98929	25593300
RB1	9884	COSM6503563,	pancreas	carcinoid-endocrine_tumour	p.V742I	Substitution - Missense	13:48465010-48465010,	PATHOGENIC	0.98928	27994516
RB1	9884	COSM6503562,	pancreas	carcinoid-endocrine_tumour	p.E746K	Substitution - Missense	13:48465022-48465022,	PATHOGENIC	0.98928	27994516
RB1	9884	COSM883,	lung	carcinoma	p.C706F	Substitution - Missense	13:48463741-48463741,	PATHOGENIC	0.98918	2168563
RB1	9884	COSM883,	lung	carcinoma	p.C706F	Substitution - Missense	13:48463741-48463741,	PATHOGENIC	0.98918	2288878
RB1	9884	COSM883,	breast	other	p.C706F	Substitution - Missense	13:48463741-48463741,	PATHOGENIC	0.98918	26832993
RB1	9884	COSM5574309,	skin	malignant_melanoma	p.S463L	Substitution - Missense	13:48379649-48379649,	PATHOGENIC	0.98912	25452114
RB1	9884	COSM5574309,	skin	malignant_melanoma	p.S463L	Substitution - Missense	13:48379649-48379649,	PATHOGENIC	0.98912	25452114
RB1	9884	COSM6909046,	lung	carcinoma	p.L647R	Substitution - Missense	13:48456329-48456329,	PATHOGENIC	0.98904	28481359
RB1	9884	COSM6201636,	kidney	carcinoma	p.?	Unknown	13:48456351-48456351,	PATHOGENIC	0.98904	26895810
RB1	9884	COSM6201636,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.?	Unknown	13:48456351-48456351,	PATHOGENIC	0.98904	28481359
RB1	9884	COSM39454,	central_nervous_system	glioma	p.?	Unknown	13:48464997-48464997,	PATHOGENIC	0.98903	18772396
RB1	9884	COSM39454,	lung	carcinoma	p.?	Unknown	13:48464997-48464997,	PATHOGENIC	0.98903	28481359
RB1	9884	COSM6908592,	lung	carcinoma	p.W681*	Substitution - Nonsense	13:48459769-48459769,	PATHOGENIC	0.98903	28481359
RB1	9884	COSM6910009,	urinary_tract	carcinoma	p.M695I	Substitution - Missense	13:48459812-48459812,	PATHOGENIC	0.98903	28481359
RB1	9884	COSM6908592,	upper_aerodigestive_tract	carcinoma	p.W681*	Substitution - Nonsense	13:48459769-48459769,	PATHOGENIC	0.98903	28581676
RB1	9884	COSM6908592,	thyroid	carcinoma	p.W681*	Substitution - Nonsense	13:48459769-48459769,	PATHOGENIC	0.98903	28481359
RB1	9884	COSM866,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	26647218
RB1	9884	COSM866,	central_nervous_system	glioma	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	28481359
RB1	9884	COSM866,	breast	carcinoma	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	28481359
RB1	9884	COSM866,	soft_tissue	leiomyosarcoma	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	28481359
RB1	9884	COSM866,	large_intestine	carcinoma	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	28481359
RB1	9884	COSM866,	urinary_tract	carcinoma	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	28481359
RB1	9884	COSM6909836,	lung	carcinoma	p.C706Y	Substitution - Missense	13:48463741-48463741,	PATHOGENIC	0.98897	28481359
RB1	9884	COSM866,	bone	osteosarcoma	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	8187094
RB1	9884	COSM866,	stomach	carcinoma	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	28481359
RB1	9884	COSM866,	skin	carcinoma	p.R467*	Substitution - Nonsense	13:48380062-48380062,	PATHOGENIC	0.98897	28481359
RB1	9884	COSM6914920,	endometrium	carcinoma	p.A658V	Substitution - Missense	13:48459700-48459700,	PATHOGENIC	0.98869	28481359
RB1	9884	COSM6910278,	urinary_tract	carcinoma	p.P609S	Substitution - Missense	13:48456214-48456214,	PATHOGENIC	0.98865	28481359
RB1	9884	COSM871,	prostate	carcinoma	p.S612P	Substitution - Missense	13:48456223-48456223,	PATHOGENIC	0.98847	7501543
RB1	9884	COSM6506791,	cervix	carcinoma	p.K715N	Substitution - Missense	13:48463769-48463769,	PATHOGENIC	0.98844	28731050
RB1	9884	COSM241369,	large_intestine	carcinoma	p.?	Unknown	13:48465204-48465204,	PATHOGENIC	0.98832	28481359
RB1	9884	COSM6938137,	upper_aerodigestive_tract	carcinoma	p.S807*	Substitution - Nonsense	13:48465299-48465299,	PATHOGENIC	0.98828	28481359
RB1	9884	COSM6938137,	lung	carcinoma	p.S807*	Substitution - Nonsense	13:48465299-48465299,	PATHOGENIC	0.98828	28481359
RB1	9884	COSM6976935,	lung	carcinoma	p.?	Unknown	13:48381245-48381245,	PATHOGENIC	0.98821	28481359
RB1	9884	COSM5610465,	skin	malignant_melanoma	p.R908L	Substitution - Missense	13:48480007-48480007,	PATHOGENIC	0.98815	26343386
RB1	9884	COSM1026,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.?	Unknown	13:48465203-48465203,	PATHOGENIC	0.98812	11103795
RB1	9884	COSM1026,	eye	retinoblastoma	p.?	Unknown	13:48465203-48465203,	PATHOGENIC	0.98812	12955724
RB1	9884	COSM327254,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y659H	Substitution - Missense	13:48459702-48459702,	PATHOGENIC	0.98809	22675565
RB1	9884	COSM6995432,	ovary	germ_cell_tumour	p.L647F	Substitution - Missense	13:48456328-48456328,	PATHOGENIC	0.98794	28954785
RB1	9884	COSM6763467,	large_intestine	carcinoma	p.E533K	Substitution - Missense	13:48381345-48381345,	PATHOGENIC	0.98778	28481359
RB1	9884	COSM6987545,	breast	carcinoma	p.E554K	Substitution - Missense	13:48381408-48381408,	PATHOGENIC	0.98778	28481359
RB1	9884	COSM6763467,	large_intestine	carcinoma	p.E533K	Substitution - Missense	13:48381345-48381345,	PATHOGENIC	0.98778	28481359
RB1	9884	COSM1367257,	thyroid	carcinoma	p.W563*	Substitution - Nonsense	13:48381436-48381436,	PATHOGENIC	0.98778	28481359
RB1	9884	COSM48894,	lung	carcinoma	p.W563*	Substitution - Nonsense	13:48381437-48381437,	PATHOGENIC	0.98778	18948947
RB1	9884	COSM1367257,	skin	carcinoma	p.W563*	Substitution - Nonsense	13:48381436-48381436,	PATHOGENIC	0.98778	28481359
RB1	9884	COSM326321,	adrenal_gland	adrenal_cortical_carcinoma	p.L665R	Substitution - Missense	13:48459721-48459721,	PATHOGENIC	0.98761	24747643
RB1	9884	COSM6963759,	soft_tissue	gastrointestinal_stromal_tumour	p.L477R	Substitution - Missense	13:48380173-48380173,	PATHOGENIC	0.98752	28481359
RB1	9884	COSM6922102,	central_nervous_system	glioma	p.?	Unknown	13:48380052-48380052,	PATHOGENIC	0.98737	28481359
RB1	9884	COSM6922102,	skin	carcinoma	p.?	Unknown	13:48380052-48380052,	PATHOGENIC	0.98737	28481359
RB1	9884	COSM6987623,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D701V	Substitution - Missense	13:48459829-48459829,	PATHOGENIC	0.98717	28481359
RB1	9884	COSM4940255,	lung	carcinoma	p.?	Unknown	13:48379652-48379652,	PATHOGENIC	0.98709	28481359
RB1	9884	COSM1040,	eye	retinoblastoma	p.?	Unknown	13:48456351-48456351,	PATHOGENIC	0.98709	2594029
RB1	9884	COSM6970261,	lung	carcinoma	p.?	Unknown	13:48465203-48465203,	PATHOGENIC	0.98703	28481359
RB1	9884	COSM6915686,	large_intestine	carcinoma	p.Q504P	Substitution - Missense	13:48381259-48381259,	PATHOGENIC	0.98688	28481359
RB1	9884	COSM254910,	urinary_tract	carcinoma	p.K765*	Substitution - Nonsense	13:48465079-48465079,	PATHOGENIC	0.98687	21822268
RB1	9884	COSM6438193,	large_intestine	carcinoma	p.M761L	Substitution - Missense	13:48465067-48465067,	PATHOGENIC	0.98687	27756406
RB1	9884	COSM1644939,	salivary_gland	carcinoma	p.Y606C	Substitution - Missense	13:48456206-48456206,	PATHOGENIC	0.98687	28481359
RB1	9884	COSM6970063,	large_intestine	carcinoma	p.K740E	Substitution - Missense	13:48465004-48465004,	PATHOGENIC	0.98683	28481359
RB1	9884	COSM6924261,	urinary_tract	carcinoma	p.?	Unknown	13:48465203-48465203,	PATHOGENIC	0.98665	28481359
RB1	9884	COSM6924261,	pancreas	carcinoma	p.?	Unknown	13:48465203-48465203,	PATHOGENIC	0.98665	28481359
RB1	9884	COSM254915,	pancreas	carcinoma	p.A488V	Substitution - Missense	13:48380206-48380206,	PATHOGENIC	0.98643	27203738
RB1	9884	COSM254915,	urinary_tract	carcinoma	p.A488V	Substitution - Missense	13:48380206-48380206,	PATHOGENIC	0.98643	21822268
RB1	9884	COSM254915,	large_intestine	carcinoma	p.A488V	Substitution - Missense	13:48380206-48380206,	PATHOGENIC	0.98643	28481359
RB1	9884	COSM212665,	urinary_tract	carcinoma	p.E747*	Substitution - Nonsense	13:48465025-48465025,	PATHOGENIC	0.98628	28481359
RB1	9884	COSM1942317,	liver	carcinoma	p.Q436*	Substitution - Nonsense	13:48377008-48377008,	PATHOGENIC	0.98555	28481359
RB1	9884	COSM6941518,	breast	carcinoma	p.S751C	Substitution - Missense	13:48465038-48465038,	PATHOGENIC	0.98554	28481359
RB1	9884	COSM6915158,	lung	carcinoma	p.K530I	Substitution - Missense	13:48381337-48381337,	PATHOGENIC	0.98513	28481359
RB1	9884	COSM6914867,	large_intestine	carcinoma	p.E691*	Substitution - Nonsense	13:48459798-48459798,	PATHOGENIC	0.98488	28481359
RB1	9884	COSM6947508,	urinary_tract	carcinoma	p.L491P	Substitution - Missense	13:48380215-48380215,	PATHOGENIC	0.98482	28481359
RB1	9884	COSM3399399,	lung	carcinoma	p.L779*	Substitution - Nonsense	13:48465215-48465215,	PATHOGENIC	0.98471	28481359
RB1	9884	COSM889,	eye	retinoblastoma	p.K720*	Substitution - Nonsense	13:48463782-48463782,	PATHOGENIC	0.98462	9311732
RB1	9884	COSM76180,	NS	malignant_melanoma	p.Q702K	Substitution - Missense	13:48459831-48459831,	PATHOGENIC	0.9846	28481359
RB1	9884	COSM6958955,	upper_aerodigestive_tract	carcinoma	p.E747K	Substitution - Missense	13:48465025-48465025,	PATHOGENIC	0.98451	28481359
RB1	9884	COSM6924891,	lung	carcinoma	p.K615*	Substitution - Nonsense	13:48456232-48456232,	PATHOGENIC	0.98427	28481359
RB1	9884	COSM95653,	thyroid	carcinoma	p.Y728*	Substitution - Nonsense	13:48463808-48463808,	PATHOGENIC	0.98424	28481359
RB1	9884	COSM95653,	lung	carcinoma	p.Y728*	Substitution - Nonsense	13:48463808-48463808,	PATHOGENIC	0.98424	20668451
RB1	9884	COSM4215369,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.W516*	Substitution - Nonsense	13:48381296-48381296,	PATHOGENIC	0.98405	27276561
RB1	9884	COSM6878797,	upper_aerodigestive_tract	carcinoma	p.S795L	Substitution - Missense	13:48465263-48465263,	PATHOGENIC	0.98405	28481359
RB1	9884	COSM4215369,	lung	carcinoma	p.W516*	Substitution - Nonsense	13:48381296-48381296,	PATHOGENIC	0.98405	28481359
RB1	9884	COSM4215369,	pancreas	carcinoma	p.W516*	Substitution - Nonsense	13:48381296-48381296,	PATHOGENIC	0.98405	28481359
RB1	9884	COSM4215369,	skin	carcinoma	p.W516*	Substitution - Nonsense	13:48381296-48381296,	PATHOGENIC	0.98405	28481359
RB1	9884	COSM4384829,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P786S	Substitution - Missense	13:48465235-48465235,	PATHOGENIC	0.98341	24030381
RB1	9884	COSM4384829,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P786S	Substitution - Missense	13:48465235-48465235,	PATHOGENIC	0.98341	24030381
RB1	9884	COSM5020253,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A525G	Substitution - Missense	13:48381322-48381322,	PATHOGENIC	0.98323	27534895
RB1	9884	COSM5020253,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A525G	Substitution - Missense	13:48381322-48381322,	PATHOGENIC	0.98323	27534895
RB1	9884	COSM5020253,	soft_tissue	haemangioblastoma	p.A525G	Substitution - Missense	13:48381322-48381322,	PATHOGENIC	0.98323	25589003
RB1	9884	COSM5944164,	bone	osteosarcoma	p.E677*	Substitution - Nonsense	13:48459756-48459756,	PATHOGENIC	0.98283	27499911
RB1	9884	COSM6955591,	urinary_tract	carcinoma	p.L719F	Substitution - Missense	13:48463779-48463779,	PATHOGENIC	0.98253	28481359
RB1	9884	COSM254913,	endometrium	carcinoma	p.E440K	Substitution - Missense	13:48377020-48377020,	PATHOGENIC	0.98249	28481359
RB1	9884	COSM254913,	urinary_tract	carcinoma	p.E440K	Substitution - Missense	13:48377020-48377020,	PATHOGENIC	0.98249	21822268
RB1	9884	COSM254913,	endometrium	carcinoma	p.E440K	Substitution - Missense	13:48377020-48377020,	PATHOGENIC	0.98249	28481359
RB1	9884	COSM1636648,	eye	retinoblastoma	p.?	Unknown	13:48459835-48459835,	PATHOGENIC	0.98238	23715307
RB1	9884	COSM6958953,	upper_aerodigestive_tract	carcinoma	p.F721L	Substitution - Missense	13:48463787-48463787,	PATHOGENIC	0.98232	28481359
RB1	9884	COSM947802,	skin	malignant_melanoma	p.F755I	Substitution - Missense	13:48465049-48465049,	PATHOGENIC	0.98139	28481359
RB1	9884	COSM3955644,	breast	carcinoma	p.M695K	Substitution - Missense	13:48459811-48459811,	PATHOGENIC	0.98133	28481359
RB1	9884	COSM6921251,	urinary_tract	carcinoma	p.?	Unknown	13:48459835-48459835,	PATHOGENIC	0.98133	28481359
RB1	9884	COSM13117,	lung	carcinoma	p.Q685*	Substitution - Nonsense	13:48459780-48459780,	PATHOGENIC	0.98032	28481359
RB1	9884	COSM13117,	lung	carcinoma	p.Q685*	Substitution - Nonsense	13:48459780-48459780,	PATHOGENIC	0.98032	28481359
RB1	9884	COSM6438180,	large_intestine	carcinoma	p.T687I	Substitution - Missense	13:48459787-48459787,	PATHOGENIC	0.98032	27756406
RB1	9884	COSM22911,	upper_aerodigestive_tract	carcinoma	p.Q702*	Substitution - Nonsense	13:48459831-48459831,	PATHOGENIC	0.98032	28581676
RB1	9884	COSM13117,	eye	retinoblastoma	p.Q685*	Substitution - Nonsense	13:48459780-48459780,	PATHOGENIC	0.98032	23715307
RB1	9884	COSM6971523,	breast	carcinoma	p.K4*	Substitution - Nonsense	13:48303922-48303922,	PATHOGENIC	0.98014	28481359
RB1	9884	COSM176711,	large_intestine	carcinoma	p.R451C	Substitution - Missense	13:48379612-48379612,	PATHOGENIC	0.98012	28481359
RB1	9884	COSM176711,	endometrium	carcinoma	p.R451C	Substitution - Missense	13:48379612-48379612,	PATHOGENIC	0.98012	28481359
RB1	9884	COSM176711,	endometrium	carcinoma	p.R451C	Substitution - Missense	13:48379612-48379612,	PATHOGENIC	0.98012	28481359
RB1	9884	COSM6925712,	urinary_tract	carcinoma	p.S773F	Substitution - Missense	13:48465104-48465104,	PATHOGENIC	0.98007	28481359
RB1	9884	COSM947804,	lung	carcinoma	p.Q762*	Substitution - Nonsense	13:48465070-48465070,	PATHOGENIC	0.98007	28481359
RB1	9884	COSM3399397,	lung	carcinoma	p.Q770*	Substitution - Nonsense	13:48465094-48465094,	PATHOGENIC	0.98007	28481359
RB1	9884	COSM947804,	large_intestine	carcinoma	p.Q762*	Substitution - Nonsense	13:48465070-48465070,	PATHOGENIC	0.98007	27756406
RB1	9884	COSM6438136,	lung	carcinoma	p.L550*	Substitution - Nonsense	13:48381397-48381397,	PATHOGENIC	0.98003	27105513
RB1	9884	COSM6438136,	lung	carcinoma	p.L550*	Substitution - Nonsense	13:48381397-48381397,	PATHOGENIC	0.98003	27105513
RB1	9884	COSM49017,	breast	carcinoma	p.L607I	Substitution - Missense	13:48456208-48456208,	PATHOGENIC	0.97997	20594292
RB1	9884	COSM6944927,	lung	carcinoma	p.D918N	Substitution - Missense	13:48480036-48480036,	PATHOGENIC	0.97957	28481359
RB1	9884	COSM6944927,	skin	carcinoma	p.D918N	Substitution - Missense	13:48480036-48480036,	PATHOGENIC	0.97957	28481359
RB1	9884	COSM22930,	lung	carcinoma	p.Q504*	Substitution - Nonsense	13:48381258-48381258,	PATHOGENIC	0.97956	28481359
RB1	9884	COSM5047406,	oesophagus	carcinoma	p.K429*	Substitution - Nonsense	13:48376987-48376987,	PATHOGENIC	0.97929	24686850
RB1	9884	COSM6191574,	lung	carcinoma	p.H673Y	Substitution - Missense	13:48459744-48459744,	PATHOGENIC	0.97928	26645239
RB1	9884	COSM6849528,	breast	carcinoma	p.I532N	Substitution - Missense	13:48381343-48381343,	PATHOGENIC	0.97881	28270497
RB1	9884	COSM5546623,	breast	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26527317
RB1	9884	COSM5546623,	thyroid	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26971368
RB1	9884	COSM5546623,	breast	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26527317
RB1	9884	COSM5546623,	breast	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26527317
RB1	9884	COSM5546623,	thyroid	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26971368
RB1	9884	COSM6958527,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.?	Unknown	13:48459835-48459835,	PATHOGENIC	0.97876	28481359
RB1	9884	COSM5546623,	breast	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26527317
RB1	9884	COSM5546623,	breast	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26527317
RB1	9884	COSM5546623,	breast	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26527317
RB1	9884	COSM5546623,	thyroid	carcinoma	p.I680T	Substitution - Missense	13:48459766-48459766,	PATHOGENIC	0.97876	26971368
RB1	9884	COSM942,	eye	retinoblastoma	p.L688P	Substitution - Missense	13:48459790-48459790,	PATHOGENIC	0.97876	15166261
RB1	9884	COSM6974187,	central_nervous_system	glioma	p.L523*	Substitution - Nonsense	13:48381316-48381316,	PATHOGENIC	0.97869	28481359
RB1	9884	COSM1050,	pancreas	carcinoid-endocrine_tumour	p.S474N	Substitution - Missense	13:48380084-48380084,	PATHOGENIC	0.97761	27994516
RB1	9884	COSM1050,	eye	retinoblastoma	p.S474N	Substitution - Missense	13:48380084-48380084,	PATHOGENIC	0.97761	14625809
RB1	9884	COSM35888,	breast	carcinoma	p.P515L	Substitution - Missense	13:48381292-48381292,	PATHOGENIC	0.97732	19593635
RB1	9884	COSM6913261,	urinary_tract	carcinoma	p.?	Unknown	13:48381246-48381246,	PATHOGENIC	0.97697	28481359
RB1	9884	COSM6913261,	skin	carcinoma	p.?	Unknown	13:48381246-48381246,	PATHOGENIC	0.97697	28481359
RB1	9884	COSM6916887,	central_nervous_system	glioma	p.G818S	Substitution - Missense	13:48465331-48465331,	PATHOGENIC	0.9768	28481359
RB1	9884	COSM6916887,	central_nervous_system	glioma	p.G818S	Substitution - Missense	13:48465331-48465331,	PATHOGENIC	0.9768	28481359
RB1	9884	COSM947805,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R787Q	Substitution - Missense	13:48465239-48465239,	PATHOGENIC	0.97668	24030381
RB1	9884	COSM6964985,	skin	malignant_melanoma	p.L521P	Substitution - Missense	13:48381310-48381310,	PATHOGENIC	0.97594	28481359
RB1	9884	COSM6913288,	prostate	carcinoma	p.?	Unknown	13:48453112-48453112,	PATHOGENIC	0.97578	28481359
RB1	9884	COSM225014,	adrenal_gland	adrenal_cortical_adenoma	p.V654M	Substitution - Missense	13:48456349-48456349,	PATHOGENIC	0.97559	24747643
RB1	9884	COSM225014,	lung	carcinoma	p.V654M	Substitution - Missense	13:48456349-48456349,	PATHOGENIC	0.97559	28481359
RB1	9884	COSM6966830,	urinary_tract	carcinoma	p.S391*	Substitution - Nonsense	13:48373449-48373449,	PATHOGENIC	0.97443	28481359
RB1	9884	COSM6978748,	breast	carcinoma	p.E464*	Substitution - Nonsense	13:48380053-48380053,	PATHOGENIC	0.9743	28481359
RB1	9884	COSM416348,	lung	carcinoma	p.?	Unknown	13:48453112-48453112,	PATHOGENIC	0.97353	28481359
RB1	9884	COSM6944300,	large_intestine	carcinoma	p.G802R	Substitution - Missense	13:48465283-48465283,	PATHOGENIC	0.97313	28481359
RB1	9884	COSM6959022,	lung	carcinoma	p.V754L	Substitution - Missense	13:48465046-48465046,	PATHOGENIC	0.9731	28481359
RB1	9884	COSM6923208,	urinary_tract	carcinoma	p.S391*	Substitution - Nonsense	13:48373449-48373449,	PATHOGENIC	0.97289	28481359
RB1	9884	COSM6981531,	lung	carcinoma	p.Y454*	Substitution - Nonsense	13:48379623-48379623,	PATHOGENIC	0.97254	28481359
RB1	9884	COSM5013846,	liver	carcinoma	p.?	Unknown	13:48380243-48380243,	PATHOGENIC	0.97205	28481359
RB1	9884	COSM6953906,	breast	carcinoma	p.?	Unknown	13:48367605-48367605,	PATHOGENIC	0.97161	28481359
RB1	9884	COSM6953906,	breast	carcinoma	p.?	Unknown	13:48367605-48367605,	PATHOGENIC	0.97161	28481359
RB1	9884	COSM6842417,	skin	carcinoma	p.E364*	Substitution - Nonsense	13:48368567-48368567,	PATHOGENIC	0.97072	28984303
RB1	9884	COSM6910280,	urinary_tract	carcinoma	p.H784Y	Substitution - Missense	13:48465229-48465229,	PATHOGENIC	0.9706	28481359
RB1	9884	COSM6964126,	skin	malignant_melanoma	p.?	Unknown	13:48373404-48373404,	PATHOGENIC	0.97051	28481359
RB1	9884	COSM416350,	lung	carcinoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.97023	28481359
RB1	9884	COSM6995455,	ovary	germ_cell_tumour	p.M904I	Substitution - Missense	13:48477403-48477403,	PATHOGENIC	0.96989	28954785
RB1	9884	COSM1651764,	urinary_tract	carcinoma	p.Y606*	Substitution - Nonsense	13:48456207-48456207,	PATHOGENIC	0.96952	28481359
RB1	9884	COSM1651764,	soft_tissue	liposarcoma	p.Y606*	Substitution - Nonsense	13:48456207-48456207,	PATHOGENIC	0.96952	20601955
RB1	9884	COSM6001062,	lung	carcinoma	p.V654L	Substitution - Missense	13:48456349-48456349,	PATHOGENIC	0.96936	28481359
RB1	9884	COSM6001062,	lung	carcinoma	p.V654L	Substitution - Missense	13:48456349-48456349,	PATHOGENIC	0.96936	28481359
RB1	9884	COSM6961672,	large_intestine	carcinoma	p.R7Q	Substitution - Missense	13:48303932-48303932,	PATHOGENIC	0.96928	28481359
RB1	9884	COSM6438177,	large_intestine	carcinoma	p.I703V	Substitution - Missense	13:48463731-48463731,	PATHOGENIC	0.96812	27756406
RB1	9884	COSM6966619,	lung	carcinoma	p.E629K	Substitution - Missense	13:48456274-48456274,	PATHOGENIC	0.96797	28481359
RB1	9884	COSM911,	ovary	carcinoma	p.L389*	Substitution - Nonsense	13:48373443-48373443,	PATHOGENIC	0.96773	28481359
RB1	9884	COSM911,	eye	retinoblastoma	p.L389*	Substitution - Nonsense	13:48373443-48373443,	PATHOGENIC	0.96773	8178820
RB1	9884	COSM911,	ovary	carcinoma	p.L389*	Substitution - Nonsense	13:48373443-48373443,	PATHOGENIC	0.96773	28481359
RB1	9884	COSM5610469,	skin	malignant_melanoma	p.L385*	Substitution - Nonsense	13:48373431-48373431,	PATHOGENIC	0.96773	26343386
RB1	9884	COSM6942782,	large_intestine	carcinoma	p.R656Q	Substitution - Missense	13:48459694-48459694,	PATHOGENIC	0.96691	28481359
RB1	9884	COSM5991501,	skin	adnexal_tumour	p.V456I	Substitution - Missense	13:48379627-48379627,	PATHOGENIC	0.9663	27311873
RB1	9884	COSM1559418,	central_nervous_system	glioma	p.?	Unknown	13:48380086-48380086,	PATHOGENIC	0.96606	28481359
RB1	9884	COSM6980729,	large_intestine	carcinoma	p.S624Y	Substitution - Missense	13:48456260-48456260,	PATHOGENIC	0.964	28481359
RB1	9884	COSM6915007,	prostate	carcinoma	p.D332H	Substitution - Missense	13:48367548-48367548,	PATHOGENIC	0.96397	28481359
RB1	9884	COSM1015,	central_nervous_system	glioma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	26919320
RB1	9884	COSM1015,	eye	retinoblastoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	2601691
RB1	9884	COSM1015,	lung	carcinoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	28481359
RB1	9884	COSM1015,	central_nervous_system	glioma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	28481359
RB1	9884	COSM1015,	lung	carcinoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	28481359
RB1	9884	COSM1015,	central_nervous_system	glioma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	28481359
RB1	9884	COSM1015,	bone	osteosarcoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	9559293
RB1	9884	COSM1015,	eye	retinoblastoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	9311732
RB1	9884	COSM1015,	urinary_tract	carcinoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	21822268
RB1	9884	COSM1015,	eye	retinoblastoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	9311732
RB1	9884	COSM1015,	prostate	carcinoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	28481359
RB1	9884	COSM1015,	eye	retinoblastoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	2601691
RB1	9884	COSM1015,	eye	retinoblastoma	p.?	Unknown	13:48373493-48373493,	PATHOGENIC	0.96379	12955724
RB1	9884	COSM35483,	breast	carcinoma	p.?	Unknown	13:48453113-48453113,	PATHOGENIC	0.96276	28481359
RB1	9884	COSM6942539,	soft_tissue	leiomyosarcoma	p.?	Unknown	13:48368525-48368525,	PATHOGENIC	0.96262	28481359
RB1	9884	COSM895,	skin	malignant_melanoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	8968104
RB1	9884	COSM895,	prostate	carcinoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	28481359
RB1	9884	COSM895,	pancreas	carcinoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	28481359
RB1	9884	COSM895,	central_nervous_system	primitive_neuroectodermal_tumour-medulloblastoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	28481359
RB1	9884	COSM895,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	28481359
RB1	9884	COSM895,	skin	malignant_melanoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	8968104
RB1	9884	COSM895,	eye	retinoblastoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	9311732
RB1	9884	COSM895,	eye	retinoblastoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	8346255
RB1	9884	COSM895,	skin	malignant_melanoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	8968104
RB1	9884	COSM895,	eye	retinoblastoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	8178820
RB1	9884	COSM895,	skin	malignant_melanoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	23851445
RB1	9884	COSM895,	oesophagus	carcinoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	24686850
RB1	9884	COSM895,	skin	carcinoma	p.R455*	Substitution - Nonsense	13:48379624-48379624,	PATHOGENIC	0.96198	25589618
RB1	9884	COSM6924555,	upper_aerodigestive_tract	carcinoma	p.S648*	Substitution - Nonsense	13:48456332-48456332,	PATHOGENIC	0.96187	28481359
RB1	9884	COSM1666882,	urinary_tract	carcinoma	p.?	Unknown	13:48368526-48368526,	PATHOGENIC	0.96153	23887298
RB1	9884	COSM3724510,	eye	retinoblastoma	p.E843*	Substitution - Nonsense	13:48476707-48476707,	PATHOGENIC	0.96125	24688104
RB1	9884	COSM317951,	skin	carcinoma	p.E322*	Substitution - Nonsense	13:48367518-48367518,	PATHOGENIC	0.9612	28481359
RB1	9884	COSM6506631,	stomach	carcinoma	p.V754I	Substitution - Missense	13:48465046-48465046,	PATHOGENIC	0.96115	25656989
RB1	9884	COSM6939349,	large_intestine	carcinoma	p.D32N	Substitution - Missense	13:48304006-48304006,	PATHOGENIC	0.96082	28481359
RB1	9884	COSM6972063,	large_intestine	carcinoma	p.K462E	Substitution - Missense	13:48379645-48379645,	PATHOGENIC	0.96012	28481359
RB1	9884	COSM5610471,	skin	malignant_melanoma	p.N295H	Substitution - Missense	13:48364915-48364915,	PATHOGENIC	0.95974	26343386
RB1	9884	COSM5731131,	breast	other	p.N849I	Substitution - Missense	13:48476726-48476726,	PATHOGENIC	0.95961	26832993
RB1	9884	COSM861,	skin	adnexal_tumour	p.R661W	Substitution - Missense	13:48459708-48459708,	PATHOGENIC	0.95912	27311873
RB1	9884	COSM861,	urinary_tract	carcinoma	p.R661W	Substitution - Missense	13:48459708-48459708,	PATHOGENIC	0.95912	28548125
RB1	9884	COSM861,	bone	osteosarcoma	p.R661W	Substitution - Missense	13:48459708-48459708,	PATHOGENIC	0.95912	27499911
RB1	9884	COSM861,	urinary_tract	carcinoma	p.R661W	Substitution - Missense	13:48459708-48459708,	PATHOGENIC	0.95912	28481359
RB1	9884	COSM861,	urinary_tract	carcinoma	p.R661W	Substitution - Missense	13:48459708-48459708,	PATHOGENIC	0.95912	7710951
RB1	9884	COSM861,	urinary_tract	carcinoma	p.R661W	Substitution - Missense	13:48459708-48459708,	PATHOGENIC	0.95912	28481359
RB1	9884	COSM4605964,	upper_aerodigestive_tract	carcinoma	p.E275*	Substitution - Nonsense	13:48362919-48362919,	PATHOGENIC	0.95846	25056374
RB1	9884	COSM6911720,	lung	carcinoma	p.?	Unknown	13:48304050-48304050,	PATHOGENIC	0.9582	28481359
RB1	9884	COSM6920267,	breast	carcinoma	p.S888T	Substitution - Missense	13:48476843-48476843,	PATHOGENIC	0.95771	28481359
RB1	9884	COSM6191614,	large_intestine	carcinoma	p.K294E	Substitution - Missense	13:48364912-48364912,	PATHOGENIC	0.95689	25617745
RB1	9884	COSM1580298,	urinary_tract	carcinoma	p.S397*	Substitution - Nonsense	13:48373467-48373467,	PATHOGENIC	0.95617	28481359
RB1	9884	COSM6908737,	endometrium	carcinoma	p.R251Q	Substitution - Missense	13:48362848-48362848,	PATHOGENIC	0.95523	28481359
RB1	9884	COSM6506790,	cervix	carcinoma	p.D340N	Substitution - Missense	13:48367572-48367572,	PATHOGENIC	0.95521	28731050
RB1	9884	COSM1367201,	large_intestine	carcinoma	p.E322K	Substitution - Missense	13:48367518-48367518,	PATHOGENIC	0.95521	28481359
RB1	9884	COSM1367201,	endometrium	carcinoma	p.E322K	Substitution - Missense	13:48367518-48367518,	PATHOGENIC	0.95521	28481359
RB1	9884	COSM1477255,	breast	carcinoma	p.R334K	Substitution - Missense	13:48367555-48367555,	PATHOGENIC	0.95521	28481359
RB1	9884	COSM432458,	lung	carcinoma	p.E864*	Substitution - Nonsense	13:48476770-48476770,	PATHOGENIC	0.95472	28481359
RB1	9884	COSM6945843,	NS	carcinoma	p.M851I	Substitution - Missense	13:48476733-48476733,	PATHOGENIC	0.95472	28481359
RB1	9884	COSM432458,	breast	carcinoma	p.E864*	Substitution - Nonsense	13:48476770-48476770,	PATHOGENIC	0.95472	27284958
RB1	9884	COSM3724518,	eye	retinoblastoma	p.?	Unknown	13:48473394-48473394,	PATHOGENIC	0.95443	24688104
RB1	9884	COSM925,	ovary	carcinoma	p.R798W	Substitution - Missense	13:48465271-48465271,	PATHOGENIC	0.95335	9194486
RB1	9884	COSM5991500,	skin	adnexal_tumour	p.E352K	Substitution - Missense	13:48368531-48368531,	PATHOGENIC	0.9532	27311873
RB1	9884	COSM6915160,	lung	carcinoma	p.S671F	Substitution - Missense	13:48459739-48459739,	PATHOGENIC	0.95272	28481359
RB1	9884	COSM903,	eye	retinoblastoma	p.Y498*	Substitution - Nonsense	13:48380237-48380237,	PATHOGENIC	0.95233	9311732
RB1	9884	COSM1367191,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R262Q	Substitution - Missense	13:48362881-48362881,	PATHOGENIC	0.95226	24030381
RB1	9884	COSM5610460,	skin	malignant_melanoma	p.E275K	Substitution - Missense	13:48362919-48362919,	PATHOGENIC	0.95226	26343386
RB1	9884	COSM6985336,	lung	carcinoma	p.K329*	Substitution - Nonsense	13:48367539-48367539,	PATHOGENIC	0.95224	28481359
RB1	9884	COSM4170227,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D332G	Substitution - Missense	13:48367549-48367549,	PATHOGENIC	0.95204	25115387
RB1	9884	COSM6962102,	skin	malignant_melanoma	p.D286N	Substitution - Missense	13:48362952-48362952,	PATHOGENIC	0.9518	28481359
RB1	9884	COSM880,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.R445*	Substitution - Nonsense	13:48379594-48379594,	PATHOGENIC	0.951	28481359
RB1	9884	COSM880,	lung	carcinoma	p.R445*	Substitution - Nonsense	13:48379594-48379594,	PATHOGENIC	0.951	28481359
RB1	9884	COSM880,	eye	retinoblastoma	p.R445*	Substitution - Nonsense	13:48379594-48379594,	PATHOGENIC	0.951	9311732
RB1	9884	COSM880,	biliary_tract	carcinoma	p.R445*	Substitution - Nonsense	13:48379594-48379594,	PATHOGENIC	0.951	28481359
RB1	9884	COSM880,	eye	retinoblastoma	p.R445*	Substitution - Nonsense	13:48379594-48379594,	PATHOGENIC	0.951	12402348
RB1	9884	COSM5701006,	lung	carcinoma	p.S618*	Substitution - Nonsense	13:48456242-48456242,	PATHOGENIC	0.95025	28481359
RB1	9884	COSM5701006,	lung	carcinoma	p.S618*	Substitution - Nonsense	13:48456242-48456242,	PATHOGENIC	0.95025	26168399
RB1	9884	COSM6494245,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D856N	Substitution - Missense	13:48476746-48476746,	PATHOGENIC	0.95018	27534895
RB1	9884	COSM6966300,	soft_tissue	liposarcoma	p.D878N	Substitution - Missense	13:48476812-48476812,	PATHOGENIC	0.95018	28481359
RB1	9884	COSM5945309,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M851I	Substitution - Missense	13:48476733-48476733,	PATHOGENIC	0.95018	27276561
RB1	9884	COSM6965279,	lung	carcinoma	p.G304*	Substitution - Nonsense	13:48364942-48364942,	PATHOGENIC	0.94982	28481359
RB1	9884	COSM5731094,	breast	other	p.I848R	Substitution - Missense	13:48476723-48476723,	PATHOGENIC	0.94982	26832993
RB1	9884	COSM6972241,	NS	carcinoma	p.K240*	Substitution - Nonsense	13:48360127-48360127,	PATHOGENIC	0.94776	28481359
RB1	9884	COSM6191616,	large_intestine	carcinoma	p.K873T	Substitution - Missense	13:48476798-48476798,	PATHOGENIC	0.94725	25617745
RB1	9884	COSM219066,	pancreas	carcinoma	p.?	Unknown	13:48362959-48362959,	PATHOGENIC	0.94715	22251937
RB1	9884	COSM6913423,	urinary_tract	carcinoma	p.Q384*	Substitution - Nonsense	13:48373427-48373427,	PATHOGENIC	0.94713	28481359
RB1	9884	COSM6986482,	urinary_tract	carcinoma	p.S397L	Substitution - Missense	13:48373467-48373467,	PATHOGENIC	0.94686	28481359
RB1	9884	COSM3793328,	lung	carcinoma	p.S397*	Substitution - Nonsense	13:48373467-48373467,	PATHOGENIC	0.94664	28481359
RB1	9884	COSM3793328,	oesophagus	carcinoma	p.S397*	Substitution - Nonsense	13:48373467-48373467,	PATHOGENIC	0.94664	24686850
RB1	9884	COSM3793328,	oesophagus	carcinoma	p.S397*	Substitution - Nonsense	13:48373467-48373467,	PATHOGENIC	0.94664	24686850
RB1	9884	COSM6913560,	lung	carcinoma	p.?	Unknown	13:48304051-48304051,	PATHOGENIC	0.94657	28481359
RB1	9884	COSM6913560,	prostate	carcinoma	p.?	Unknown	13:48304051-48304051,	PATHOGENIC	0.94657	28481359
RB1	9884	COSM6438195,	large_intestine	carcinoma	p.L731F	Substitution - Missense	13:48463815-48463815,	PATHOGENIC	0.94647	27756406
RB1	9884	COSM916,	central_nervous_system	glioma	p.V754G	Substitution - Missense	13:48465047-48465047,	PATHOGENIC	0.9461	8674005
RB1	9884	COSM916,	central_nervous_system	glioma	p.V754G	Substitution - Missense	13:48465047-48465047,	PATHOGENIC	0.9461	10328544
RB1	9884	COSM4990379,	skin	carcinoma	p.E209*	Substitution - Nonsense	13:48360034-48360034,	PATHOGENIC	0.946	25589618
RB1	9884	COSM6932427,	central_nervous_system	glioma	p.Y446*	Substitution - Nonsense	13:48379599-48379599,	PATHOGENIC	0.94561	28481359
RB1	9884	COSM13404,	lung	carcinoma	p.Q850*	Substitution - Nonsense	13:48476728-48476728,	PATHOGENIC	0.94554	28481359
RB1	9884	COSM6927123,	lung	carcinoma	p.L400V	Substitution - Missense	13:48373475-48373475,	PATHOGENIC	0.94515	28481359
RB1	9884	COSM6935084,	urinary_tract	carcinoma	p.E30A	Substitution - Missense	13:48304001-48304001,	PATHOGENIC	0.94365	28481359
RB1	9884	COSM6946315,	large_intestine	carcinoma	p.F296V	Substitution - Missense	13:48364918-48364918,	PATHOGENIC	0.94262	28481359
RB1	9884	COSM6926699,	breast	carcinoma	p.E315*	Substitution - Nonsense	13:48367497-48367497,	PATHOGENIC	0.94146	28481359
RB1	9884	COSM5574308,	large_intestine	adenoma	p.R656W	Substitution - Missense	13:48459693-48459693,	PATHOGENIC	0.94143	27609830
RB1	9884	COSM5574308,	skin	malignant_melanoma	p.R656W	Substitution - Missense	13:48459693-48459693,	PATHOGENIC	0.94143	25452114
RB1	9884	COSM5574308,	large_intestine	carcinoma	p.R656W	Substitution - Missense	13:48459693-48459693,	PATHOGENIC	0.94143	28481359
RB1	9884	COSM5574308,	NS	malignant_melanoma	p.R656W	Substitution - Missense	13:48459693-48459693,	PATHOGENIC	0.94143	25148578
RB1	9884	COSM5574308,	NS	malignant_melanoma	p.R656W	Substitution - Missense	13:48459693-48459693,	PATHOGENIC	0.94143	25148578
RB1	9884	COSM5574308,	skin	malignant_melanoma	p.R656W	Substitution - Missense	13:48459693-48459693,	PATHOGENIC	0.94143	25452114
RB1	9884	COSM5574308,	stomach	carcinoma	p.R656W	Substitution - Missense	13:48459693-48459693,	PATHOGENIC	0.94143	25656989
RB1	9884	COSM317953,	lung	carcinoma	p.V654V	Substitution - coding silent	13:48459689-48459689,	PATHOGENIC	0.94101	22941188
RB1	9884	COSM1942383,	lung	carcinoma	p.G581*	Substitution - Nonsense	13:48453038-48453038,	PATHOGENIC	0.94084	28481359
RB1	9884	COSM214151,	skin	carcinoma	p.W195*	Substitution - Nonsense	13:48349001-48349001,	PATHOGENIC	0.9398	24406863
RB1	9884	COSM214151,	breast	carcinoma	p.W195*	Substitution - Nonsense	13:48349001-48349001,	PATHOGENIC	0.9398	28481359
RB1	9884	COSM214151,	breast	carcinoma	p.W195*	Substitution - Nonsense	13:48349001-48349001,	PATHOGENIC	0.9398	28481359
RB1	9884	COSM6438191,	large_intestine	carcinoma	p.H555Y	Substitution - Missense	13:48381411-48381411,	PATHOGENIC	0.93972	27756406
RB1	9884	COSM888,	pancreas	carcinoid-endocrine_tumour	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	28481359
RB1	9884	COSM888,	urinary_tract	carcinoma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	29420467
RB1	9884	COSM888,	adrenal_gland	adrenal_cortical_carcinoma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	28481359
RB1	9884	COSM888,	eye	retinoblastoma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	9311732
RB1	9884	COSM888,	eye	retinoblastoma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	9311732
RB1	9884	COSM888,	eye	retinoblastoma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	8346255
RB1	9884	COSM888,	prostate	carcinoma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	28481359
RB1	9884	COSM888,	urinary_tract	carcinoma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	28481359
RB1	9884	COSM888,	central_nervous_system	glioma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	18772396
RB1	9884	COSM888,	urinary_tract	carcinoma	p.R556*	Substitution - Nonsense	13:48381414-48381414,	PATHOGENIC	0.93892	28481359
RB1	9884	COSM1562227,	oesophagus	carcinoma	p.R255Q	Substitution - Missense	13:48362860-48362860,	PATHOGENIC	0.93846	24686850
RB1	9884	COSM254909,	liver	carcinoma	p.?	Unknown	13:48360016-48360016,	PATHOGENIC	0.93843	28481359
RB1	9884	COSM254909,	urinary_tract	carcinoma	p.?	Unknown	13:48360016-48360016,	PATHOGENIC	0.93843	21822268
RB1	9884	COSM254909,	NS	malignant_melanoma	p.?	Unknown	13:48360016-48360016,	PATHOGENIC	0.93843	28481359
RB1	9884	COSM254909,	skin	malignant_melanoma	p.?	Unknown	13:48360016-48360016,	PATHOGENIC	0.93843	28481359
RB1	9884	COSM3724517,	eye	retinoblastoma	p.?	Unknown	13:48364889-48364889,	PATHOGENIC	0.93788	24688104
RB1	9884	COSM6438179,	large_intestine	carcinoma	p.H686Y	Substitution - Missense	13:48459783-48459783,	PATHOGENIC	0.9373	27756406
RB1	9884	COSM6438179,	large_intestine	carcinoma	p.H686Y	Substitution - Missense	13:48459783-48459783,	PATHOGENIC	0.9373	27756406
RB1	9884	COSM6939469,	NS	carcinoma	p.P822S	Substitution - Missense	13:48465343-48465343,	PATHOGENIC	0.93704	28481359
RB1	9884	COSM3399394,	soft_tissue	leiomyosarcoma	p.L335*	Substitution - Nonsense	13:48367558-48367558,	PATHOGENIC	0.93673	28481359
RB1	9884	COSM5700973,	lung	carcinoma	p.?	Unknown	13:48345079-48345079,	PATHOGENIC	0.93637	26168399
RB1	9884	COSM317958,	lung	carcinoma	p.L199*	Substitution - Nonsense	13:48349012-48349012,	PATHOGENIC	0.93445	22941188
RB1	9884	COSM6924319,	lung	carcinoma	p.D479E	Substitution - Missense	13:48380180-48380180,	PATHOGENIC	0.93442	28481359
RB1	9884	COSM6951167,	central_nervous_system	glioma	p.?	Unknown	13:48452992-48452992,	PATHOGENIC	0.93414	28481359
RB1	9884	COSM1367176,	large_intestine	carcinoma	p.?	Unknown	13:48347864-48347864,	PATHOGENIC	0.93413	28481359
RB1	9884	COSM1367176,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.?	Unknown	13:48347864-48347864,	PATHOGENIC	0.93413	28481359
RB1	9884	COSM938,	prostate	carcinoma	p.E323*	Substitution - Nonsense	13:48367521-48367521,	PATHOGENIC	0.93408	24823478
RB1	9884	COSM938,	eye	retinoblastoma	p.E323*	Substitution - Nonsense	13:48367521-48367521,	PATHOGENIC	0.93408	8346255
RB1	9884	COSM938,	lung	carcinoma	p.E323*	Substitution - Nonsense	13:48367521-48367521,	PATHOGENIC	0.93408	28481359
RB1	9884	COSM938,	large_intestine	carcinoma	p.E323*	Substitution - Nonsense	13:48367521-48367521,	PATHOGENIC	0.93408	28481359
RB1	9884	COSM938,	large_intestine	carcinoma	p.E323*	Substitution - Nonsense	13:48367521-48367521,	PATHOGENIC	0.93408	28481359
RB1	9884	COSM5030963,	central_nervous_system	glioma	p.L335*	Substitution - Nonsense	13:48367558-48367558,	PATHOGENIC	0.93322	28481359
RB1	9884	COSM5030963,	salivary_gland	carcinoma	p.L335*	Substitution - Nonsense	13:48367558-48367558,	PATHOGENIC	0.93322	26053092
RB1	9884	COSM126899,	endometrium	carcinoma	p.Q257*	Substitution - Nonsense	13:48362865-48362865,	PATHOGENIC	0.93209	28481359
RB1	9884	COSM126899,	breast	carcinoma	p.Q257*	Substitution - Nonsense	13:48362865-48362865,	PATHOGENIC	0.93209	28481359
RB1	9884	COSM1046,	pituitary	adenoma	p.R621S	Substitution - Missense	13:48456250-48456250,	PATHOGENIC	0.93193	12114739
RB1	9884	COSM1046,	stomach	carcinoma	p.R621S	Substitution - Missense	13:48456250-48456250,	PATHOGENIC	0.93193	26489445
RB1	9884	COSM1046,	breast	carcinoma	p.R621S	Substitution - Missense	13:48456250-48456250,	PATHOGENIC	0.93193	27284958
RB1	9884	COSM915,	skin	malignant_melanoma	p.L199*	Substitution - Nonsense	13:48349012-48349012,	PATHOGENIC	0.93153	23851445
RB1	9884	COSM915,	skin	malignant_melanoma	p.L199*	Substitution - Nonsense	13:48349012-48349012,	PATHOGENIC	0.93153	8968104
RB1	9884	COSM915,	skin	malignant_melanoma	p.L199*	Substitution - Nonsense	13:48349012-48349012,	PATHOGENIC	0.93153	8968104
RB1	9884	COSM915,	skin	malignant_melanoma	p.L199*	Substitution - Nonsense	13:48349012-48349012,	PATHOGENIC	0.93153	8968104
RB1	9884	COSM6984565,	endometrium	carcinoma	p.V291A	Substitution - Missense	13:48364904-48364904,	PATHOGENIC	0.93139	28481359
RB1	9884	COSM6976254,	lung	carcinoma	p.D604G	Substitution - Missense	13:48453108-48453108,	PATHOGENIC	0.93062	28481359
RB1	9884	COSM6438178,	large_intestine	carcinoma	p.D139V	Substitution - Missense	13:48345115-48345115,	PATHOGENIC	0.92959	27756406
RB1	9884	COSM6438176,	large_intestine	carcinoma	p.E587V	Substitution - Missense	13:48453057-48453057,	PATHOGENIC	0.92952	27756406
RB1	9884	COSM6242339,	upper_aerodigestive_tract	carcinoma	p.?	Unknown	13:48452991-48452991,	PATHOGENIC	0.92923	28481359
RB1	9884	COSM6951218,	lung	carcinoma	p.M546I	Substitution - Missense	13:48381386-48381386,	PATHOGENIC	0.92834	28481359
RB1	9884	COSM6986602,	lung	carcinoma	p.C666*	Substitution - Nonsense	13:48459725-48459725,	PATHOGENIC	0.928	28481359
RB1	9884	COSM6920656,	NS	carcinoma	p.A160S	Substitution - Missense	13:48345177-48345177,	PATHOGENIC	0.92614	28481359
RB1	9884	COSM13403,	lung	carcinoma	p.E166*	Substitution - Nonsense	13:48345195-48345195,	PATHOGENIC	0.92614	28481359
RB1	9884	COSM5047280,	oesophagus	carcinoma	p.R262W	Substitution - Missense	13:48362880-48362880,	PATHOGENIC	0.92576	24686850
RB1	9884	COSM4384823,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G100A	Substitution - Missense	13:48342633-48342633,	PATHOGENIC	0.92568	24030381
RB1	9884	COSM6441198,	upper_aerodigestive_tract	carcinoma	p.?	Unknown	13:48367493-48367493,	PATHOGENIC	0.92565	28493366
RB1	9884	COSM3733293,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R857L	Substitution - Missense	13:48476750-48476750,	PATHOGENIC	0.92536	24682267
RB1	9884	COSM6438183,	large_intestine	carcinoma	p.P732S	Substitution - Missense	13:48463818-48463818,	PATHOGENIC	0.92306	27756406
RB1	9884	COSM4806230,	lung	carcinoma	p.Q266*	Substitution - Nonsense	13:48362892-48362892,	PATHOGENIC	0.92129	28481359
RB1	9884	COSM6962514,	urinary_tract	carcinoma	p.P6S	Substitution - Missense	13:48303928-48303928,	PATHOGENIC	0.92102	28481359
RB1	9884	COSM13118,	salivary_gland	carcinoma	p.S567*	Substitution - Nonsense	13:48452997-48452997,	PATHOGENIC	0.92072	27334835
RB1	9884	COSM13118,	lung	carcinoma	p.S567*	Substitution - Nonsense	13:48452997-48452997,	PATHOGENIC	0.92072	22941188
RB1	9884	COSM1017,	eye	retinoblastoma	p.?	Unknown	13:48342715-48342715,	PATHOGENIC	0.92068	9311732
RB1	9884	COSM1017,	lung	carcinoma	p.?	Unknown	13:48342715-48342715,	PATHOGENIC	0.92068	28481359
RB1	9884	COSM6952329,	large_intestine	carcinoma	p.D111Y	Substitution - Missense	13:48342665-48342665,	PATHOGENIC	0.91904	28481359
RB1	9884	COSM6932677,	endometrium	carcinoma	p.G100*	Substitution - Nonsense	13:48342632-48342632,	PATHOGENIC	0.91904	28481359
RB1	9884	COSM6842049,	breast	carcinoma	p.?	Unknown	13:48347866-48347866,	PATHOGENIC	0.91586	28685160
RB1	9884	COSM171725,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E280*	Substitution - Nonsense	13:48362934-48362934,	PATHOGENIC	0.91426	24682267
RB1	9884	COSM5369762,	lung	carcinoma	p.K154*	Substitution - Nonsense	13:48345159-48345159,	PATHOGENIC	0.91121	26164066
RB1	9884	COSM6920682,	lung	carcinoma	p.?	Unknown	13:48367492-48367492,	PATHOGENIC	0.91113	28481359
RB1	9884	COSM6920682,	lung	carcinoma	p.?	Unknown	13:48367492-48367492,	PATHOGENIC	0.91113	28481359
RB1	9884	COSM6920682,	lung	carcinoma	p.?	Unknown	13:48367492-48367492,	PATHOGENIC	0.91113	28481359
RB1	9884	COSM6922949,	skin	malignant_melanoma	p.K447I	Substitution - Missense	13:48379601-48379601,	PATHOGENIC	0.9108	28481359
RB1	9884	COSM6947381,	large_intestine	carcinoma	p.S560P	Substitution - Missense	13:48381426-48381426,	PATHOGENIC	0.91056	28481359
RB1	9884	COSM6913802,	thyroid	carcinoma	p.E672*	Substitution - Nonsense	13:48459741-48459741,	PATHOGENIC	0.90986	28481359
RB1	9884	COSM6977085,	lung	carcinoma	p.R544*	Substitution - Nonsense	13:48381378-48381378,	PATHOGENIC	0.90896	28481359
RB1	9884	COSM6977085,	cervix	carcinoma	p.R544*	Substitution - Nonsense	13:48381378-48381378,	PATHOGENIC	0.90896	28481359
RB1	9884	COSM1735721,	skin	carcinoma	p.W99*	Substitution - Nonsense	13:48342631-48342631,	PATHOGENIC	0.90842	24406863
RB1	9884	COSM1735722,	skin	carcinoma	p.G100R	Substitution - Missense	13:48342632-48342632,	PATHOGENIC	0.90842	24406863
RB1	9884	COSM5029210,	breast	carcinoma	p.W99*	Substitution - Nonsense	13:48342630-48342630,	PATHOGENIC	0.90842	22722193
RB1	9884	COSM1735721,	central_nervous_system	glioma	p.W99*	Substitution - Nonsense	13:48342631-48342631,	PATHOGENIC	0.90842	28481359
RB1	9884	COSM1731707,	skin	carcinoma	p.Q597*	Substitution - Nonsense	13:48453086-48453086,	PATHOGENIC	0.90811	24406863
RB1	9884	COSM5574307,	skin	malignant_melanoma	p.I227N	Substitution - Missense	13:48360089-48360089,	PATHOGENIC	0.90799	25452114
RB1	9884	COSM5574307,	skin	malignant_melanoma	p.I227N	Substitution - Missense	13:48360089-48360089,	PATHOGENIC	0.90799	25452114
RB1	9884	COSM6934533,	urinary_tract	carcinoma	p.S443*	Substitution - Nonsense	13:48377030-48377030,	PATHOGENIC	0.90782	28481359
RB1	9884	COSM6934533,	skin	malignant_melanoma	p.S443*	Substitution - Nonsense	13:48377030-48377030,	PATHOGENIC	0.90782	28481359
RB1	9884	COSM1300229,	central_nervous_system	glioma	p.S567L	Substitution - Missense	13:48452997-48452997,	PATHOGENIC	0.90641	28481359
RB1	9884	COSM1300229,	lung	carcinoma	p.S567L	Substitution - Missense	13:48452997-48452997,	PATHOGENIC	0.90641	28481359
RB1	9884	COSM5985099,	large_intestine	adenoma	p.K548N	Substitution - Missense	13:48381392-48381392,	PATHOGENIC	0.90345	27609830
RB1	9884	COSM6968593,	urinary_tract	carcinoma	p.E184*	Substitution - Nonsense	13:48348966-48348966,	PATHOGENIC	0.90228	28481359
RB1	9884	COSM864,	urinary_tract	carcinoma	p.S794I	Substitution - Missense	13:48465260-48465260,	PATHOGENIC	0.90215	7710951
RB1	9884	COSM3733249,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y790*	Substitution - Nonsense	13:48465249-48465249,	PATHOGENIC	0.90167	24682267
RB1	9884	COSM4384827,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R668H	Substitution - Missense	13:48459730-48459730,	PATHOGENIC	0.90161	24030381
RB1	9884	COSM13405,	breast	carcinoma	p.Q217*	Substitution - Nonsense	13:48360058-48360058,	PATHOGENIC	0.90061	28481359
RB1	9884	COSM13405,	lung	carcinoma	p.Q217*	Substitution - Nonsense	13:48360058-48360058,	PATHOGENIC	0.90061	22941188
RB1	9884	COSM13405,	lung	carcinoma	p.Q217*	Substitution - Nonsense	13:48360058-48360058,	PATHOGENIC	0.90061	18948947
RB1	9884	COSM13405,	urinary_tract	carcinoma	p.Q217*	Substitution - Nonsense	13:48360058-48360058,	PATHOGENIC	0.90061	28481359
RB1	9884	COSM13405,	lung	carcinoma	p.Q217*	Substitution - Nonsense	13:48360058-48360058,	PATHOGENIC	0.90061	28481359
RB1	9884	COSM13405,	pancreas	carcinoma	p.Q217*	Substitution - Nonsense	13:48360058-48360058,	PATHOGENIC	0.90061	28481359
RB1	9884	COSM13405,	urinary_tract	carcinoma	p.Q217*	Substitution - Nonsense	13:48360058-48360058,	PATHOGENIC	0.90061	21822268
RB1	9884	COSM3957234,	lung	carcinoma	p.?	Unknown	13:48349024-48349024,	PATHOGENIC	0.89944	28481359
RB1	9884	COSM6921063,	lung	carcinoma	p.Q35*	Substitution - Nonsense	13:48304015-48304015,	PATHOGENIC	0.89851	28481359
RB1	9884	COSM6914501,	central_nervous_system	glioma	p.S149*	Substitution - Nonsense	13:48345145-48345145,	PATHOGENIC	0.8968	28481359
RB1	9884	COSM6917081,	NS	carcinoma	p.Y655*	Substitution - Nonsense	13:48459692-48459692,	PATHOGENIC	0.89584	28481359
RB1	9884	COSM5752662,	prostate	carcinoma	p.S230*	Substitution - Nonsense	13:48360098-48360098,	PATHOGENIC	0.89481	28481359
RB1	9884	COSM6964808,	lung	carcinoma	p.K96*	Substitution - Nonsense	13:48342620-48342620,	PATHOGENIC	0.89256	28481359
RB1	9884	COSM6938784,	lung	carcinoma	p.K95*	Substitution - Nonsense	13:48342617-48342617,	PATHOGENIC	0.89256	28481359
RB1	9884	COSM6906574,	urinary_tract	carcinoma	p.R259S	Substitution - Missense	13:48362873-48362873,	PATHOGENIC	0.89077	29420467
RB1	9884	COSM4604774,	upper_aerodigestive_tract	carcinoma	p.K745*	Substitution - Nonsense	13:48465019-48465019,	PATHOGENIC	0.89042	25056374
RB1	9884	COSM5945311,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.V852I	Substitution - Missense	13:48476734-48476734,	PATHOGENIC	0.89036	27276561
RB1	9884	COSM6854767,	large_intestine	other	p.T5N	Substitution - Missense	13:48303926-48303926,	PATHOGENIC	0.88669	28524162
RB1	9884	COSM49018,	breast	carcinoma	p.R698W	Substitution - Missense	13:48459819-48459819,	PATHOGENIC	0.88489	20594292
RB1	9884	COSM1047,	eye	retinoblastoma	p.N328H	Substitution - Missense	13:48367536-48367536,	PATHOGENIC	0.88488	12187430
RB1	9884	COSM6982207,	lung	carcinoma	p.A626G	Substitution - Missense	13:48456266-48456266,	PATHOGENIC	0.88466	28481359
RB1	9884	COSM22918,	lung	carcinoma	p.S127I	Substitution - Missense	13:48342714-48342714,	PATHOGENIC	0.88392	28481359
RB1	9884	COSM4962402,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R621H	Substitution - Missense	13:48456251-48456251,	PATHOGENIC	0.88307	27276561
RB1	9884	COSM4215345,	lung	carcinoma	p.S443L	Substitution - Missense	13:48377030-48377030,	PATHOGENIC	0.88199	26168399
RB1	9884	COSM3469142,	central_nervous_system	glioma	p.?	Unknown	13:48348955-48348955,	PATHOGENIC	0.88089	28481359
RB1	9884	COSM23824,	endometrium	carcinoma	p.R787*	Substitution - Nonsense	13:48465238-48465238,	PATHOGENIC	0.87991	28481359
RB1	9884	COSM23824,	skin	carcinoma	p.R787*	Substitution - Nonsense	13:48465238-48465238,	PATHOGENIC	0.87991	28481359
RB1	9884	COSM23824,	central_nervous_system	glioma	p.R787*	Substitution - Nonsense	13:48465238-48465238,	PATHOGENIC	0.87991	28201779
RB1	9884	COSM23824,	large_intestine	carcinoma	p.R787*	Substitution - Nonsense	13:48465238-48465238,	PATHOGENIC	0.87991	28481359
RB1	9884	COSM23824,	urinary_tract	carcinoma	p.R787*	Substitution - Nonsense	13:48465238-48465238,	PATHOGENIC	0.87991	28481359
RB1	9884	COSM23824,	pleura	mesothelioma	p.R787*	Substitution - Nonsense	13:48465238-48465238,	PATHOGENIC	0.87991	26928227
RB1	9884	COSM6922333,	lung	carcinoma	p.R259S	Substitution - Missense	13:48362873-48362873,	PATHOGENIC	0.87958	28481359
RB1	9884	COSM862,	urinary_tract	carcinoma	p.I138S	Substitution - Missense	13:48345112-48345112,	PATHOGENIC	0.87849	7710951
RB1	9884	COSM13413,	liver	carcinoma	p.L158*	Substitution - Nonsense	13:48345172-48345172,	PATHOGENIC	0.87744	28481359
RB1	9884	COSM6191613,	large_intestine	carcinoma	p.T271S	Substitution - Missense	13:48362907-48362907,	PATHOGENIC	0.8771	25617745
RB1	9884	COSM6910007,	urinary_tract	carcinoma	p.S318C	Substitution - Missense	13:48367507-48367507,	PATHOGENIC	0.8758	28481359
RB1	9884	COSM5048072,	oesophagus	carcinoma	p.Q176*	Substitution - Nonsense	13:48347850-48347850,	PATHOGENIC	0.87513	24686850
RB1	9884	COSM6947886,	lung	carcinoma	p.E282*	Substitution - Nonsense	13:48362940-48362940,	PATHOGENIC	0.87397	28481359
RB1	9884	COSM6947379,	large_intestine	carcinoma	p.?	Unknown	13:48307407-48307407,	PATHOGENIC	0.87319	28481359
RB1	9884	COSM39160,	central_nervous_system	glioma	p.W75*	Substitution - Nonsense	13:48307367-48307367,	PATHOGENIC	0.872	18772396
RB1	9884	COSM6503564,	pancreas	carcinoid-endocrine_tumour	p.L161F	Substitution - Missense	13:48345180-48345180,	PATHOGENIC	0.87189	27994516
RB1	9884	COSM890,	eye	retinoblastoma	p.E137*	Substitution - Nonsense	13:48345108-48345108,	PATHOGENIC	0.87126	9311732
RB1	9884	COSM890,	eye	retinoblastoma	p.E137*	Substitution - Nonsense	13:48345108-48345108,	PATHOGENIC	0.87126	9311732
RB1	9884	COSM317960,	lung	carcinoma	p.?	Unknown	13:48342716-48342716,	PATHOGENIC	0.87007	22941188
RB1	9884	COSM35887,	breast	carcinoma	p.I388S	Substitution - Missense	13:48373440-48373440,	PATHOGENIC	0.86844	19593635
RB1	9884	COSM6494241,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48364886-48364886,	PATHOGENIC	0.86758	27534895
RB1	9884	COSM6950876,	lung	carcinoma	p.Y756*	Substitution - Nonsense	13:48465054-48465054,	PATHOGENIC	0.86756	28481359
RB1	9884	COSM5369826,	lung	carcinoma	p.P595L	Substitution - Missense	13:48453081-48453081,	PATHOGENIC	0.8672	26645239
RB1	9884	COSM5369826,	lung	carcinoma	p.P595L	Substitution - Missense	13:48453081-48453081,	PATHOGENIC	0.8672	26164066
RB1	9884	COSM6955189,	large_intestine	carcinoma	p.K80*	Substitution - Nonsense	13:48307380-48307380,	PATHOGENIC	0.86626	28481359
RB1	9884	COSM860,	urinary_tract	carcinoma	p.L158S	Substitution - Missense	13:48345172-48345172,	PATHOGENIC	0.86255	7710951
RB1	9884	COSM1367152,	central_nervous_system	glioma	p.S127N	Substitution - Missense	13:48342714-48342714,	PATHOGENIC	0.85685	28481359
RB1	9884	COSM249559,	kidney	carcinoma	p.K745I	Substitution - Missense	13:48465020-48465020,	PATHOGENIC	0.85662	22138691
RB1	9884	COSM3733320,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A18T	Substitution - Missense	13:48303964-48303964,	PATHOGENIC	0.8565	24682267
RB1	9884	COSM284491,	large_intestine	carcinoma	p.E125*	Substitution - Nonsense	13:48342707-48342707,	PATHOGENIC	0.85564	28481359
RB1	9884	COSM6958006,	central_nervous_system	glioma	p.?	Unknown	13:48342716-48342716,	PATHOGENIC	0.85457	28481359
RB1	9884	COSM6975721,	lung	carcinoma	p.F684L	Substitution - Missense	13:48459779-48459779,	PATHOGENIC	0.85393	28481359
RB1	9884	COSM7325465,	biliary_tract	carcinoma	p.G581E	Substitution - Missense	13:48453039-48453039,	PATHOGENIC	0.85284	29360550
RB1	9884	COSM868,	lung	carcinoma	p.E748*	Substitution - Nonsense	13:48465028-48465028,	PATHOGENIC	0.85226	28481359
RB1	9884	COSM868,	lung	carcinoma	p.E748*	Substitution - Nonsense	13:48465028-48465028,	PATHOGENIC	0.85226	2594029
RB1	9884	COSM868,	lung	carcinoma	p.E748*	Substitution - Nonsense	13:48465028-48465028,	PATHOGENIC	0.85226	8263009
RB1	9884	COSM6851675,	breast	carcinoma	p.F117S	Substitution - Missense	13:48342684-48342684,	PATHOGENIC	0.85179	25591616
RB1	9884	COSM6976554,	lung	carcinoma	p.L88F	Substitution - Missense	13:48307406-48307406,	PATHOGENIC	0.84526	28481359
RB1	9884	COSM927,	ovary	carcinoma	p.N123D	Substitution - Missense	13:48342701-48342701,	PATHOGENIC	0.83859	9194486
RB1	9884	COSM877,	skin	malignant_melanoma	p.S114*	Substitution - Nonsense	13:48342675-48342675,	PATHOGENIC	0.83265	26343386
RB1	9884	COSM877,	eye	retinoblastoma	p.S114*	Substitution - Nonsense	13:48342675-48342675,	PATHOGENIC	0.83265	12402348
RB1	9884	COSM696480,	lung	carcinoma	p.L88F	Substitution - Missense	13:48307406-48307406,	PATHOGENIC	0.83078	28481359
RB1	9884	COSM891,	eye	retinoblastoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	15166261
RB1	9884	COSM891,	stomach	carcinoid-endocrine_tumour	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	28481359
RB1	9884	COSM891,	breast	carcinoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	28481359
RB1	9884	COSM891,	eye	retinoblastoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	8346255
RB1	9884	COSM891,	eye	retinoblastoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	9311732
RB1	9884	COSM891,	eye	retinoblastoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	12955724
RB1	9884	COSM891,	soft_tissue	leiomyosarcoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	28481359
RB1	9884	COSM891,	eye	retinoblastoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	9311732
RB1	9884	COSM891,	pancreas	carcinoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	28481359
RB1	9884	COSM891,	kidney	carcinoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	28481359
RB1	9884	COSM891,	skin	carcinoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	28481359
RB1	9884	COSM891,	breast	carcinoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	22722193
RB1	9884	COSM891,	eye	retinoblastoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	9311732
RB1	9884	COSM891,	eye	retinoblastoma	p.R320*	Substitution - Nonsense	13:48367512-48367512,	PATHOGENIC	0.83031	9311732
RB1	9884	COSM6438194,	large_intestine	carcinoma	p.H585Y	Substitution - Missense	13:48453050-48453050,	PATHOGENIC	0.82355	27756406
RB1	9884	COSM910,	eye	retinoblastoma	p.C489*	Substitution - Nonsense	13:48380210-48380210,	PATHOGENIC	0.8234	8178820
RB1	9884	COSM144722,	eye	retinoblastoma	p.?	Unknown	13:48342597-48342597,	PATHOGENIC	0.82335	22237022
RB1	9884	COSM878,	central_nervous_system	glioma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	28481359
RB1	9884	COSM878,	eye	retinoblastoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	9311732
RB1	9884	COSM878,	lung	carcinoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	28481359
RB1	9884	COSM878,	eye	retinoblastoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	20627193
RB1	9884	COSM878,	upper_aerodigestive_tract	carcinoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	25056374
RB1	9884	COSM878,	NS	carcinoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	28481359
RB1	9884	COSM878,	skin	carcinoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	28481359
RB1	9884	COSM878,	NS	carcinoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	28481359
RB1	9884	COSM878,	breast	carcinoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	28481359
RB1	9884	COSM878,	urinary_tract	carcinoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	28481359
RB1	9884	COSM878,	eye	retinoblastoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	12402348
RB1	9884	COSM878,	urinary_tract	carcinoma	p.R251*	Substitution - Nonsense	13:48362847-48362847,	PATHOGENIC	0.81988	28481359
RB1	9884	COSM936,	upper_aerodigestive_tract	carcinoma	p.Q395*	Substitution - Nonsense	13:48373460-48373460,	PATHOGENIC	0.81891	28581676
RB1	9884	COSM936,	urinary_tract	carcinoma	p.Q395*	Substitution - Nonsense	13:48373460-48373460,	PATHOGENIC	0.81891	28481359
RB1	9884	COSM936,	lung	carcinoma	p.Q395*	Substitution - Nonsense	13:48373460-48373460,	PATHOGENIC	0.81891	28481359
RB1	9884	COSM936,	eye	retinoblastoma	p.Q395*	Substitution - Nonsense	13:48373460-48373460,	PATHOGENIC	0.81891	8346255
RB1	9884	COSM936,	urinary_tract	carcinoma	p.Q395*	Substitution - Nonsense	13:48373460-48373460,	PATHOGENIC	0.81891	28481359
RB1	9884	COSM6962312,	lung	carcinoma	p.?	Unknown	13:48342598-48342598,	PATHOGENIC	0.81805	28481359
RB1	9884	COSM4990377,	NS	malignant_melanoma	p.E137D	Substitution - Missense	13:48345110-48345110,	PATHOGENIC	0.81383	25148578
RB1	9884	COSM4990377,	NS	malignant_melanoma	p.E137D	Substitution - Missense	13:48345110-48345110,	PATHOGENIC	0.81383	25148578
RB1	9884	COSM4990377,	skin	carcinoma	p.E137D	Substitution - Missense	13:48345110-48345110,	PATHOGENIC	0.81383	25589618
RB1	9884	COSM4990377,	NS	malignant_melanoma	p.E137D	Substitution - Missense	13:48345110-48345110,	PATHOGENIC	0.81383	25148578
RB1	9884	COSM4990377,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E137D	Substitution - Missense	13:48345110-48345110,	PATHOGENIC	0.81383	27534895
RB1	9884	COSM6929570,	lung	carcinoma	p.T625A	Substitution - Missense	13:48456262-48456262,	PATHOGENIC	0.81365	28481359
RB1	9884	COSM49001,	lung	carcinoma	p.?	Unknown	13:48307408-48307408,	PATHOGENIC	0.81304	18948947
RB1	9884	COSM13140,	urinary_tract	carcinoma	p.S576*	Substitution - Nonsense	13:48453024-48453024,	PATHOGENIC	0.81279	28481359
RB1	9884	COSM13140,	breast	carcinoma	p.S576*	Substitution - Nonsense	13:48453024-48453024,	PATHOGENIC	0.81279	28270497
RB1	9884	COSM3936344,	soft_tissue	perivascular_epithelioid_cell_tumour_(PEComa)	p.?	Unknown	13:48349024-48349024,	PATHOGENIC	0.81262	28481359
RB1	9884	COSM3936344,	soft_tissue	leiomyosarcoma	p.?	Unknown	13:48349024-48349024,	PATHOGENIC	0.81262	28481359
RB1	9884	COSM3399392,	skin	carcinoma	p.C221*	Substitution - Nonsense	13:48360072-48360072,	PATHOGENIC	0.81222	28481359
RB1	9884	COSM6923294,	urinary_tract	carcinoma	p.S402Y	Substitution - Missense	13:48373482-48373482,	PATHOGENIC	0.81148	28481359
RB1	9884	COSM887,	thyroid	carcinoma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	28351340
RB1	9884	COSM887,	central_nervous_system	glioma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	28481359
RB1	9884	COSM887,	lung	carcinoma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	28481359
RB1	9884	COSM887,	eye	retinoblastoma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	8346255
RB1	9884	COSM887,	eye	retinoblastoma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	9311732
RB1	9884	COSM887,	large_intestine	carcinoma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	27756406
RB1	9884	COSM887,	eye	retinoblastoma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	9311732
RB1	9884	COSM887,	large_intestine	carcinoma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	28481359
RB1	9884	COSM887,	stomach	carcinoma	p.R552*	Substitution - Nonsense	13:48381402-48381402,	PATHOGENIC	0.80955	28481359
RB1	9884	COSM6918863,	NS	carcinoma	p.I679F	Substitution - Missense	13:48459762-48459762,	PATHOGENIC	0.80589	28481359
RB1	9884	COSM872,	prostate	carcinoma	p.S187T	Substitution - Missense	13:48348975-48348975,	PATHOGENIC	0.80128	7501543
RB1	9884	COSM13142,	urinary_tract	carcinoma	p.Q344*	Substitution - Nonsense	13:48367584-48367584,	PATHOGENIC	0.79593	21822268
RB1	9884	COSM13142,	urinary_tract	carcinoma	p.Q344*	Substitution - Nonsense	13:48367584-48367584,	PATHOGENIC	0.79593	28481359
RB1	9884	COSM5991502,	skin	adnexal_tumour	p.S318F	Substitution - Missense	13:48367507-48367507,	PATHOGENIC	0.79388	27311873
RB1	9884	COSM5029212,	breast	carcinoma	p.Q850Q	Substitution - coding silent	13:48476730-48476730,	PATHOGENIC	0.79013	22722193
RB1	9884	COSM6986122,	breast	carcinoma	p.F299L	Substitution - Missense	13:48364929-48364929,	PATHOGENIC	0.78642	28481359
RB1	9884	COSM6438184,	large_intestine	carcinoma	p.L572F	Substitution - Missense	13:48453011-48453011,	PATHOGENIC	0.78544	27756406
RB1	9884	COSM1367296,	adrenal_gland	adrenal_cortical_adenoma	p.R698S	Substitution - Missense	13:48459821-48459821,	PATHOGENIC	0.78419	28481359
RB1	9884	COSM6941507,	lung	carcinoma	p.S758*	Substitution - Nonsense	13:48465059-48465059,	PATHOGENIC	0.78373	28481359
RB1	9884	COSM13740,	lung	carcinoma	p.?	Unknown	13:48342598-48342598,	PATHOGENIC	0.7827	28481359
RB1	9884	COSM905,	lung	carcinoma	p.S82*	Substitution - Nonsense	13:48307387-48307387,	PATHOGENIC	0.77148	1992444
RB1	9884	COSM5730807,	breast	other	p.P250S	Substitution - Missense	13:48362844-48362844,	PATHOGENIC	0.77055	26437033
RB1	9884	COSM859,	urinary_tract	carcinoma	p.M208V	Substitution - Missense	13:48360031-48360031,	PATHOGENIC	0.77031	7710951
RB1	9884	COSM327253,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G310E	Substitution - Missense	13:48364961-48364961,	PATHOGENIC	0.76815	22675565
RB1	9884	COSM5730809,	breast	other	p.A264T	Substitution - Missense	13:48362886-48362886,	PATHOGENIC	0.7679	26437033
RB1	9884	COSM6506627,	stomach	carcinoma	p.P370S	Substitution - Missense	13:48368585-48368585,	PATHOGENIC	0.76077	25656989
RB1	9884	COSM5610467,	skin	malignant_melanoma	p.R857S	Substitution - Missense	13:48476749-48476749,	PATHOGENIC	0.76019	26343386
RB1	9884	COSM6926955,	lung	carcinoma	p.S163I	Substitution - Missense	13:48345187-48345187,	PATHOGENIC	0.75893	28481359
RB1	9884	COSM943,	urinary_tract	carcinoma	p.R255*	Substitution - Nonsense	13:48362859-48362859,	PATHOGENIC	0.75874	28481359
RB1	9884	COSM943,	pancreas	carcinoma	p.R255*	Substitution - Nonsense	13:48362859-48362859,	PATHOGENIC	0.75874	28481359
RB1	9884	COSM943,	upper_aerodigestive_tract	carcinoma	p.R255*	Substitution - Nonsense	13:48362859-48362859,	PATHOGENIC	0.75874	28581676
RB1	9884	COSM943,	breast	carcinoma	p.R255*	Substitution - Nonsense	13:48362859-48362859,	PATHOGENIC	0.75874	25850943
RB1	9884	COSM943,	eye	retinoblastoma	p.R255*	Substitution - Nonsense	13:48362859-48362859,	PATHOGENIC	0.75874	12955724
RB1	9884	COSM943,	eye	retinoblastoma	p.R255*	Substitution - Nonsense	13:48362859-48362859,	PATHOGENIC	0.75874	28481359
RB1	9884	COSM6919082,	lung	carcinoma	p.R73I	Substitution - Missense	13:48307360-48307360,	PATHOGENIC	0.75817	28481359
RB1	9884	COSM6438186,	large_intestine	carcinoma	p.S576L	Substitution - Missense	13:48453024-48453024,	PATHOGENIC	0.75795	27756406
RB1	9884	COSM39409,	central_nervous_system	glioma	p.?	Unknown	13:48342598-48342598,	PATHOGENIC	0.74816	18772396
RB1	9884	COSM5991640,	breast	carcinoma	p.?	Unknown	13:48349025-48349025,	PATHOGENIC	0.74769	25927147
RB1	9884	COSM48893,	lung	carcinoma	p.E79*	Substitution - Nonsense	13:48307377-48307377,	PATHOGENIC	0.74373	18948947
RB1	9884	COSM327252,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D421N	Substitution - Missense	13:48376963-48376963,	PATHOGENIC	0.74363	22675565
RB1	9884	COSM254914,	upper_aerodigestive_tract	carcinoma	p.S634*	Substitution - Nonsense	13:48456290-48456290,	PATHOGENIC	0.74311	28481359
RB1	9884	COSM254914,	urinary_tract	carcinoma	p.S634*	Substitution - Nonsense	13:48456290-48456290,	PATHOGENIC	0.74311	21822268
RB1	9884	COSM6964600,	soft_tissue	leiomyosarcoma	p.F115L	Substitution - Missense	13:48342679-48342679,	PATHOGENIC	0.73851	28481359
RB1	9884	COSM876,	soft_tissue	gastrointestinal_stromal_tumour	p.E54*	Substitution - Nonsense	13:48307302-48307302,	PATHOGENIC	0.73549	28481359
RB1	9884	COSM876,	large_intestine	carcinoma	p.E54*	Substitution - Nonsense	13:48307302-48307302,	PATHOGENIC	0.73549	28481359
RB1	9884	COSM876,	eye	retinoblastoma	p.E54*	Substitution - Nonsense	13:48307302-48307302,	PATHOGENIC	0.73549	12402348
RB1	9884	COSM4169363,	breast	other	p.K63*	Substitution - Nonsense	13:48307329-48307329,	PATHOGENIC	0.7163	26437033
RB1	9884	COSM6946313,	large_intestine	carcinoma	p.E54K	Substitution - Missense	13:48307302-48307302,	PATHOGENIC	0.71569	28481359
RB1	9884	COSM5686959,	urinary_tract	carcinoma	p.?	Unknown	13:48307278-48307278,	PATHOGENIC	0.71414	28481359
RB1	9884	COSM95157,	breast	carcinoma	p.E53K	Substitution - Missense	13:48307299-48307299,	PATHOGENIC	0.71365	20668451
RB1	9884	COSM5027768,	urinary_tract	carcinoma	p.E97*	Substitution - Nonsense	13:48342623-48342623,	PATHOGENIC	0.70795	28481359
RB1	9884	COSM6952590,	lung	carcinoma	p.Y424*	Substitution - Nonsense	13:48376974-48376974,	NEUTRAL	0.4376	28481359
RB1	9884	COSM6438190,	large_intestine	carcinoma	p.P370L	Substitution - Missense	13:48368586-48368586,	NEUTRAL	0.38128	27756406
RB1	9884	COSM6961167,	pancreas	carcinoma	p.P591H	Substitution - Missense	13:48453069-48453069,	NEUTRAL	0.32553	28481359
RB1	9884	COSM935,	eye	retinoblastoma	p.A14A	Substitution - coding silent	13:48303954-48303954,	NEUTRAL	0.31607	8346255
RB1	9884	COSM6005778,	skin	adnexal_tumour	p.C590*	Substitution - Nonsense	13:48453067-48453067,	NEUTRAL	0.30531	27287813
RB1	9884	COSM6438185,	large_intestine	carcinoma	p.L592F	Substitution - Missense	13:48453071-48453071,	NEUTRAL	0.25824	27756406
RB1	9884	COSM5610475,	skin	malignant_melanoma	p.T633A	Substitution - Missense	13:48456286-48456286,	NEUTRAL	0.20832	26343386
RB1	9884	COSM4384825,	pancreas	carcinoma	p.T620M	Substitution - Missense	13:48456248-48456248,	NEUTRAL	0.20171	28481359
RB1	9884	COSM4384825,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T620M	Substitution - Missense	13:48456248-48456248,	NEUTRAL	0.20171	24030381
RB1	9884	COSM5610458,	skin	malignant_melanoma	p.P808P	Substitution - coding silent	13:48465303-48465303,	NEUTRAL	0.19575	26343386
RB1	9884	COSM879,	eye	retinoblastoma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	20627193
RB1	9884	COSM879,	central_nervous_system	glioma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	24695838
RB1	9884	COSM879,	eye	retinoblastoma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	22237022
RB1	9884	COSM879,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	25115387
RB1	9884	COSM879,	eye	retinoblastoma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	9311732
RB1	9884	COSM879,	eye	retinoblastoma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	8346255
RB1	9884	COSM879,	skin	adnexal_tumour	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	27287813
RB1	9884	COSM879,	central_nervous_system	glioma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	24695838
RB1	9884	COSM879,	eye	retinoblastoma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	12402348
RB1	9884	COSM879,	soft_tissue	leiomyosarcoma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	28481359
RB1	9884	COSM879,	soft_tissue	leiomyosarcoma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	28481359
RB1	9884	COSM879,	eye	retinoblastoma	p.R358*	Substitution - Nonsense	13:48368549-48368549,	NEUTRAL	0.15915	22237022
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	soft_tissue	haemangioblastoma	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	25589003
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM147687,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	13:48477345-48477345,	NEUTRAL	0.09575	27534895
RB1	9884	COSM6438187,	large_intestine	carcinoma	p.N367D	Substitution - Missense	13:48368576-48368576,	NEUTRAL	0.09344	27756406
RB1	9884	COSM6763473,	stomach	carcinoma	p.R358Q	Substitution - Missense	13:48368550-48368550,	NEUTRAL	0.08044	28481359
RB1	9884	COSM924,	central_nervous_system	glioma	p.F839F	Substitution - coding silent	13:48473387-48473387,	NEUTRAL	0.03763	7979217
RB1	9884	COSM6494239,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A15A	Substitution - coding silent	13:48303957-48303957,	NEUTRAL	0.02859	27534895
RB1	9884	COSM6494239,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A15A	Substitution - coding silent	13:48303957-48303957,	NEUTRAL	0.02859	27534895
RB1	9884	COSM1011,	lung	carcinoma	p.?	Unknown	13:48379722-48379722,	NEUTRAL	0.02019	8302602
RB1	9884	COSM1051,	central_nervous_system	glioma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	10328544
RB1	9884	COSM1018, COSM1024, COSM931, COSM933,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.?, p.Q217fs*2, p.V654fs*6	Deletion - Frameshift, Insertion - Frameshift, Unknown	13:48360057-48360057,	Info_not_available	Info_not_available	11103795
RB1	9884	COSM1051,	eye	retinoblastoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	12187430
RB1	9884	COSM1032, COSM1033,	central_nervous_system	glioma	p.?	Unknown	13:48464971-48464982, 13:48464975-48464982,	Info_not_available	Info_not_available	12556968
RB1	9884	COSM904,	prostate	carcinoma	p.I703_E737del35	Deletion - In frame	13:48463731-48463835,	Info_not_available	Info_not_available	1329054
RB1	9884	COSM1051,	cervix	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	1648218
RB1	9884	COSM23573, COSM23574,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	17332242
RB1	9884	COSM19545,	central_nervous_system	glioma	p.0	Whole gene deletion	13:48303913-48480071,	Info_not_available	Info_not_available	18394558
RB1	9884	COSM39397, COSM39580, COSM39747,	central_nervous_system	glioma	p.G442fs*15, p.G449fs*8, p.P822fs*4	Deletion - Frameshift	13:48377027-48377027, 13:48379607-48379607, 13:48465344-48465344,	Info_not_available	Info_not_available	18772396
RB1	9884	COSM48966,	lung	carcinoma	p.D340fs*5	Deletion - Frameshift	13:48367571-48367593,	Info_not_available	Info_not_available	18948947
RB1	9884	COSM3736959, COSM3736960, COSM3736961, COSM3736962, COSM3736963,	breast	carcinoma	p.K715*, p.N480del, p.P21fs*?, p.R876C, p.S82del	Deletion - In frame, Frameshift, Substitution - Missense, Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	19372580
RB1	9884	COSM18651, COSM19545, COSM19551, COSM35889, COSM35890,	breast	carcinoma	p.0, p.?, p.G203fs*9, p.T738_R775del38	Deletion - In frame, Insertion - Frameshift, Unknown, Whole gene deletion	13:48303913-48480071, 13:48342599-48349023, 13:48342599-48480071, 13:48464998-48465111,	Info_not_available	Info_not_available	19593635
RB1	9884	COSM49147, COSM49148,	breast	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	20594292
RB1	9884	COSM85771,	salivary_gland	carcinoma	p.L234*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	20696054
RB1	9884	COSM19545,	bone	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.0	Whole gene deletion	13:48303913-48480071,	Info_not_available	Info_not_available	21254299
RB1	9884	COSM303840,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.M148fs*9	Insertion - Frameshift	13:48345140-48345141,	Info_not_available	Info_not_available	21680795
RB1	9884	COSM1018, COSM219814,	NS	malignant_melanoma	p.?, p.Q93*	Substitution - Nonsense, Unknown	Info_not_available	Info_not_available	Info_not_available	21725359
RB1	9884	COSM869, COSM928, COSM929,	lung	carcinoma	p.L769_Q770>F*, p.P777fs*33, p.R661fs*1	Complex - compound substitution, Deletion - Frameshift	13:48459707-48459710, 13:48465093-48465094, 13:48465209-48465209,	Info_not_available	Info_not_available	2176283
RB1	9884	COSM19545,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.0	Whole gene deletion	13:48303913-48480071,	Info_not_available	Info_not_available	22072402
RB1	9884	COSM19545,	soft_tissue	gastrointestinal_stromal_tumour	p.0	Whole gene deletion	13:48303913-48480071,	Info_not_available	Info_not_available	22167411
RB1	9884	COSM1051,	prostate	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	2217208
RB1	9884	COSM219063, COSM219064, COSM219065,	pancreas	carcinoma	p.L743fs*1, p.N269fs*1, p.N290fs*20	Deletion - Frameshift, Insertion - Frameshift	13:48362899-48362900, 13:48364900-48364901, 13:48465014-48465024,	Info_not_available	Info_not_available	22251937
RB1	9884	COSM144253, COSM144254,	eye	retinoblastoma	p.R798fs*17, p.Y173fs*11	Deletion - Frameshift, Insertion - Frameshift	13:48347839-48347840, 13:48465270-48465271,	Info_not_available	Info_not_available	22303805
RB1	9884	COSM210741,	lung	carcinoma	p.E280?	Unknown	Info_not_available	Info_not_available	Info_not_available	22327622
RB1	9884	COSM249914,	ovary	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	22328975
RB1	9884	COSM249894,	breast	carcinoma	p.?fs	Deletion - Frameshift	Info_not_available	Info_not_available	Info_not_available	22706203
RB1	9884	COSM19545,	bone	chondrosarcoma	p.0	Whole gene deletion	13:48303913-48480071,	Info_not_available	Info_not_available	23146407
RB1	9884	COSM1735719,	eye	retinoblastoma	p.I679fs*1	Insertion - Frameshift	13:48459761-48459762,	Info_not_available	Info_not_available	23289805
RB1	9884	COSM1716319, COSM1716320, COSM1716321, COSM1716322, COSM1716323, COSM19545,	eye	retinoblastoma	p.0, p.?	Unknown, Whole gene deletion	13:48303913-48480071, 13:48381247-48381443,	Info_not_available	Info_not_available	23441118
RB1	9884	COSM1238044,	skin	malignant_melanoma	p.E79K	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	23444215
RB1	9884	COSM1666878, COSM1666879, COSM1666880, COSM1666881, COSM1666883,	urinary_tract	carcinoma	p.?, p.Q62*, p.Q685fs*11, p.S758*, p.W195*	Substitution - Nonsense, Unknown	Info_not_available	Info_not_available	Info_not_available	23887298
RB1	9884	COSM1666669, COSM1666670,	breast	other	p.K740*, p.Q504*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	23895135
RB1	9884	COSM3734747, COSM3734748, COSM3734749, COSM3734750, COSM3734751,	urinary_tract	carcinoma	p.G617fs*36, p.Q344*, p.Q762*, p.S397*, p.Y239*	Frameshift, Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	24192927
RB1	9884	COSM1737865,	skin	carcinoma	p.R741fs*5	Deletion - Frameshift	Info_not_available	Info_not_available	Info_not_available	24406863
RB1	9884	COSM3734770,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.419fs*?	Unknown	13:48376957-48376979,	Info_not_available	Info_not_available	24497536
RB1	9884	COSM1051,	skin	malignant_melanoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	24628946
RB1	9884	COSM3733437,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S576fs*34	Deletion - Frameshift	13:48453023-48453026,	Info_not_available	Info_not_available	24682267
RB1	9884	COSM432450, COSM5047620, COSM5048006,	oesophagus	carcinoma	p.A74fs*4, p.E97fs*13, p.S671_E672>*	Complex - deletion inframe, Insertion - Frameshift	13:48307352-48307353, 13:48342616-48342617, 13:48459739-48459741,	Info_not_available	Info_not_available	24686850
RB1	9884	COSM3724511, COSM3724512, COSM3724513, COSM3724514, COSM3724515, COSM3724516,	eye	retinoblastoma	p.?, p.D584fs*2, p.E747fs*3, p.L832fs*5, p.Q384fs*11, p.T58fs*52	Deletion - Frameshift, Insertion - Frameshift, Unknown	13:48307313-48307314, 13:48373426-48373427, 13:48380083-48380084, 13:48453046-48453047, 13:48465026-48465027, 13:48473366-48473367,	Info_not_available	Info_not_available	24688104
RB1	9884	COSM4387489,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.0	Whole gene deletion	Info_not_available	Info_not_available	Info_not_available	24997557
RB1	9884	COSM19545, COSM4169702,	adrenal_gland	adrenal_cortical_carcinoma	p.0, p.S414fs*10	Frameshift, Whole gene deletion	13:48303913-48480071,	Info_not_available	Info_not_available	25078331
RB1	9884	COSM6006460, COSM6006461,	NS	malignant_melanoma	p.C706fs*14, p.R358*	Deletion - Frameshift, Substitution - Nonsense	13:48368548-48368549, 13:48463741-48463742,	Info_not_available	Info_not_available	25148578
RB1	9884	COSM4989866, COSM4989867, COSM4989868,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?, p.Q436K	Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	25207766
RB1	9884	COSM4603673, COSM4603674, COSM4603675, COSM4603676, COSM4603677,	pancreas	carcinoma	p.?, p.A74fs*4, p.H483fs*12, p.I244fs*6, p.R251*	Frameshift, Substitution - Nonsense, Unknown	Info_not_available	Info_not_available	Info_not_available	25266736
RB1	9884	COSM5945668,	stomach	carcinoid-endocrine_tumour	p.R358*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	25342539
RB1	9884	COSM4603673,	central_nervous_system	glioma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	25529192
RB1	9884	COSM4984819,	lung	carcinoma	p.Y321*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	25567908
RB1	9884	COSM4990381,	skin	carcinoma	p.M484fs*8	Deletion - Frameshift	13:48380191-48380192,	Info_not_available	Info_not_available	25589618
RB1	9884	COSM5575591, COSM5575598,	ovary	carcinoma	p.C666fs*1, p.L135fs*5	Deletion - Frameshift, Insertion - Frameshift	13:48345100-48345101, 13:48459717-48459718,	Info_not_available	Info_not_available	25846551
RB1	9884	COSM5024932,	breast	carcinoma	p.E837fs*12	Deletion - Frameshift	13:48473380-48473380,	Info_not_available	Info_not_available	25850943
RB1	9884	COSM5023016,	thyroid	carcinoma	p.N290fs*11	Deletion - Frameshift	13:48364901-48364901,	Info_not_available	Info_not_available	25862857
RB1	9884	COSM5731075,	NS	malignant_melanoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	25886620
RB1	9884	COSM19545,	urinary_tract	carcinoma	p.0	Whole gene deletion	13:48303913-48480071,	Info_not_available	Info_not_available	25891343
RB1	9884	COSM5991639,	breast	carcinoma	p.D156fs*19	Frameshift	Info_not_available	Info_not_available	Info_not_available	25927147
RB1	9884	COSM906, COSM907,	eye	retinoblastoma	p.E748fs*6, p.T841fs*8	Deletion - Frameshift	13:48465030-48465030, 13:48473390-48473390,	Info_not_available	Info_not_available	2594029
RB1	9884	COSM4603673, COSM7002273,	NS	malignant_melanoma	p.?, p.R455*	Substitution - Nonsense, Unknown	Info_not_available	Info_not_available	Info_not_available	25956405
RB1	9884	COSM6057032,	lung	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	25971939
RB1	9884	COSM5701004, COSM5702489,	lung	carcinoma	p.D145fs*8, p.V144S	Deletion - Frameshift, Substitution - Missense	13:48345129-48345130, 13:48345130-48345130,	Info_not_available	Info_not_available	26168399
RB1	9884	COSM4603673, COSM6023951, COSM6024014, COSM6024015, COSM6024016, COSM6024017, COSM6024018, COSM6024019, COSM6024020,	NS	carcinoma	p.?, p.G437fs*20, p.H129fs*3, p.I124fs*6, p.P231fs*9, p.V754fs*1, p.V754fs*11, p.V87fs*24, p.W99*	Frameshift, Substitution - Nonsense, Unknown	Info_not_available	Info_not_available	Info_not_available	26182302
RB1	9884	COSM5751885,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E209fs*3	Insertion - Frameshift	13:48360034-48360035,	Info_not_available	Info_not_available	26206799
RB1	9884	COSM5351741,	lung	carcinoma	p.E458*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	26400668
RB1	9884	COSM5676772, COSM5731027,	breast	other	p.E629fs*23, p.S318fs*13	Deletion - Frameshift	13:48367502-48367505, 13:48456273-48456274,	Info_not_available	Info_not_available	26437033
RB1	9884	COSM249914,	prostate	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	26444865
RB1	9884	COSM4387489,	soft_tissue	liposarcoma	p.0	Whole gene deletion	Info_not_available	Info_not_available	Info_not_available	26647907
RB1	9884	COSM5731092, COSM5731096, COSM5731128, COSM5731157, COSM5731162,	breast	other	p.D156fs*19, p.D697fs*23, p.G310fs*22, p.P250fs*20, p.P609fs*43	Deletion - Frameshift	13:48345166-48345166, 13:48362844-48362845, 13:48364960-48364960, 13:48456209-48456210, 13:48459812-48459813,	Info_not_available	Info_not_available	26832993
RB1	9884	COSM4387489,	kidney	carcinoma	p.0	Whole gene deletion	Info_not_available	Info_not_available	Info_not_available	26895810
RB1	9884	COSM6506607,	breast	carcinoma	p.S758P	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27034166
RB1	9884	COSM6438116,	lung	carcinoma	p.P777fs*33	Deletion - Frameshift	13:48465205-48465205,	Info_not_available	Info_not_available	27105513
RB1	9884	COSM5885271,	thyroid	carcinoma	p.S463fs*?	Frameshift	Info_not_available	Info_not_available	Info_not_available	27245685
RB1	9884	COSM5885127, COSM5885128,	biliary_tract	carcinoma	p.R579*, p.S576L	Substitution - Missense, Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	27267833
RB1	9884	COSM6904140,	breast	carcinoma	p.E97fs*5	Deletion - Frameshift	13:48342623-48342650,	Info_not_available	Info_not_available	27284958
RB1	9884	COSM249914, COSM5967131, COSM5967132, COSM5967133,	salivary_gland	carcinoma	p.?, p.K615fs*36, p.L665fs*9, p.S618fs*5	Deletion - Frameshift, Unknown	13:48456233-48456237, 13:48456241-48456241, 13:48459721-48459787,	Info_not_available	Info_not_available	27334835
RB1	9884	COSM4603673,	cervix	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	27499905
RB1	9884	COSM6022478,	lung	carcinoma	p.Q575*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	27528220
RB1	9884	COSM6438181, COSM6438182, COSM6438188, COSM6438189,	large_intestine	carcinoma	p.N133fs*3, p.N593fs*5, p.P370fs*10, p.P595fs*16	Deletion - Frameshift	13:48345096-48345096, 13:48368585-48368585, 13:48453073-48453077, 13:48453080-48453080,	Info_not_available	Info_not_available	27756406
RB1	9884	COSM6024088,	central_nervous_system	glioma	p.R798fs*17	Frameshift	Info_not_available	Info_not_available	Info_not_available	28042970
RB1	9884	COSM4387489,	central_nervous_system	glioma	p.0	Whole gene deletion	Info_not_available	Info_not_available	Info_not_available	28201779
RB1	9884	COSM6849727,	breast	carcinoma	p.E323fs*9	Deletion - Frameshift	13:48367521-48367521,	Info_not_available	Info_not_available	28270497
RB1	9884	COSM1051,	kidney	Wilms_tumour	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	28326956
RB1	9884	COSM19545,	soft_tissue	leiomyosarcoma	p.0	Whole gene deletion	13:48303913-48480071,	Info_not_available	Info_not_available	28476787
RB1	9884	COSM6904497, COSM6904498,	upper_aerodigestive_tract	carcinoma	p.C221*, p.K319fs*?	Frameshift, Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	28493366
RB1	9884	COSM6834819,	ovary	carcinoma	p.S463*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	28734796
RB1	9884	COSM6842520,	soft_tissue	fibrosarcoma	p.D156fs*19	Deletion - Frameshift	13:48345165-48345165,	Info_not_available	Info_not_available	28776571
RB1	9884	COSM6904656,	breast	carcinoma	p.E693fs*?	Frameshift	Info_not_available	Info_not_available	Info_not_available	28921573
RB1	9884	COSM1666880, COSM3734751,	urinary_tract	carcinoma	p.Q344*, p.Q62*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	28945843
RB1	9884	COSM6906268,	urinary_tract	carcinoma	p.R556*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	29413684
RB1	9884	COSM6906340, COSM6906889,	urinary_tract	carcinoma	p.D32fs*33, p.M148fs*8	Deletion - Frameshift	13:48304005-48304005, 13:48345140-48345141,	Info_not_available	Info_not_available	29420467
RB1	9884	COSM1051, COSM4603673, COSM7002310, COSM7002324, COSM7002372,	central_nervous_system	glioma	p.?, p.R698Afs*22, p.S182Yfs*2	Frameshift, Unknown	Info_not_available	Info_not_available	Info_not_available	29683790
RB1	9884	COSM1031, COSM941,	breast	carcinoma	p.?, p.G203fs*8	Insertion - Frameshift, Unknown	Info_not_available	Info_not_available	Info_not_available	3388033
RB1	9884	COSM873, COSM874,	prostate	carcinoma	p.N258fs*6, p.S513fs*9	Deletion - Frameshift	13:48362869-48362869, 13:48381285-48381286,	Info_not_available	Info_not_available	7501543
RB1	9884	COSM875,	kidney	carcinoma	p.K240_A242>T	Complex - deletion inframe	13:48362815-48362820,	Info_not_available	Info_not_available	7579728
RB1	9884	COSM857, COSM858, COSM863,	urinary_tract	carcinoma	p.E677fs*19, p.E693fs*3, p.K896_F897>I	Complex - deletion inframe, Deletion - Frameshift	13:48459758-48459758, 13:48459804-48459804, 13:48477378-48477380,	Info_not_available	Info_not_available	7710951
RB1	9884	COSM1022, COSM1044, COSM923,	central_nervous_system	glioma	p.?, p.?fs, p.N258fs*11	Deletion - Frameshift, Unknown	13:48362865-48362869, 13:48473361-48473361, 13:48473393-48473393,	Info_not_available	Info_not_available	7979217
RB1	9884	COSM884, COSM885,	liver	carcinoma	p.L389fs*3, p.T77fs*34	Deletion - Frameshift	13:48307371-48307371, 13:48373444-48373451,	Info_not_available	Info_not_available	8033150
RB1	9884	COSM904,	ovary	carcinoma	p.I703_E737del35	Deletion - In frame	13:48463731-48463835,	Info_not_available	Info_not_available	8077050
RB1	9884	COSM1043, COSM908, COSM909, COSM912, COSM913, COSM914,	eye	retinoblastoma	p.E413fs*4, p.L647fs*5, p.N472_F473insK, p.R71fs*39, p.T502fs*22, p.Y771fs*24	Complex - frameshift, Deletion - Frameshift, Insertion - Frameshift, Insertion - In frame	13:48307352-48307353, 13:48376938-48376938, 13:48380079-48380080, 13:48381252-48381258, 13:48456328-48456329, 13:48465096-48465097,	Info_not_available	Info_not_available	8178820
RB1	9884	COSM1051, COSM867,	bone	osteosarcoma	p.?, p.P808fs*12	Deletion - Frameshift, Unknown	13:48465301-48465319,	Info_not_available	Info_not_available	8187094
RB1	9884	COSM930,	lung	carcinoid-endocrine_tumour	p.I831fs*8	Deletion - Frameshift	13:48473360-48473390,	Info_not_available	Info_not_available	8222834
RB1	9884	COSM1051, COSM870,	lung	carcinoma	p.?, p.L676fs*16	Deletion - Frameshift, Unknown	13:48459755-48459767,	Info_not_available	Info_not_available	8263009
RB1	9884	COSM1051,	lung	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	8302602
RB1	9884	COSM1027, COSM1028, COSM1045, COSM914, COSM934, COSM937, COSM939,	eye	retinoblastoma	p.?, p.F162fs*13, p.L134fs*1, p.L647fs*5, p.N406fs*4, p.N480fs*13	Complex - frameshift, Deletion - Frameshift, Insertion - Frameshift, Unknown	13:48345100-48345103, 13:48345183-48345184, 13:48345201-48345201, 13:48376918-48376939, 13:48380181-48380182, 13:48456328-48456329, 13:48473393-48473396,	Info_not_available	Info_not_available	8346255
RB1	9884	COSM1023,	lung	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	8390038
RB1	9884	COSM858,	urinary_tract	carcinoma	p.E693fs*3	Deletion - Frameshift	13:48459804-48459804,	Info_not_available	Info_not_available	8561864
RB1	9884	COSM1051,	central_nervous_system	glioma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	8674005
RB1	9884	COSM1025,	endometrium	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	8677081
RB1	9884	COSM1018,	eye	retinoblastoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	9140452
RB1	9884	COSM1020,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	9204979
RB1	9884	COSM917, COSM918, COSM919, COSM920, COSM921, COSM922,	lung	carcinoma	p.C712_A727del16, p.F684fs*12, p.K722fs*29, p.L832fs*1, p.M484fs*8, p.P783fs*27	Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift	13:48380195-48380196, 13:48459778-48459778, 13:48463757-48463804, 13:48463784-48463785, 13:48465225-48465225, 13:48473365-48473365,	Info_not_available	Info_not_available	9476905
RB1	9884	COSM1035, COSM1036, COSM1037,	bone	osteosarcoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	9559293
RB1	9884	COSM1607122,	liver	carcinoma	p.?	Unknown	13:48348954-48348967,	Info_not_available	Info_not_available	Info_not_available
RB1	9884	COSM1636647,	eye	retinoblastoma	p.S634P	Substitution - Missense	13:48456289-48456289,	Info_not_available	0.68427	23715307
RB1	9884	COSM944,	eye	retinoblastoma	p.Y325*	Substitution - Nonsense	13:48367529-48367529,	Info_not_available	0.68222	12955724
RB1	9884	COSM6908607, COSM6987746,	upper_aerodigestive_tract	carcinoma	p.L64*, p.Q354fs*7	Deletion - Frameshift, Substitution - Nonsense	13:48307333-48307333, 13:48368537-48368538,	Info_not_available	0.68126, Info_not_available	28581676
RB1	9884	COSM1021,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	13:48342724-48342724,	Info_not_available	0.65957	10803523
RB1	9884	COSM6005780, COSM6005785, COSM6005788, COSM6006329,	skin	adnexal_tumour	p.A635fs*6, p.D224fs*40, p.E204*, p.K574fs*1	Deletion - Frameshift, Insertion - Frameshift, Substitution - Nonsense	13:48360019-48360019, 13:48360080-48360080, 13:48453016-48453017, 13:48456293-48456299,	Info_not_available	0.65765, Info_not_available	27287813
RB1	9884	COSM5369780,	lung	carcinoma	p.L594F	Substitution - Missense	13:48453077-48453077,	Info_not_available	0.65576	26164066
RB1	9884	COSM5021112,	soft_tissue	haemangioblastoma	p.I274I	Substitution - coding silent	13:48362918-48362918,	Info_not_available	0.63172	25589003
RB1	9884	COSM4771412,	breast	carcinoma	p.Y321*	Substitution - Nonsense	13:48367517-48367517,	Info_not_available	0.61851	24185512
RB1	9884	COSM5030944, COSM5030945, COSM5030962,	salivary_gland	carcinoma	p.?, p.Y155*	Substitution - Nonsense, Unknown	13:48345164-48345164,	Info_not_available	0.59396, Info_not_available	26053092
RB1	9884	COSM317952, COSM317957, COSM892,	lung	carcinoma	p.?, p.N186fs*6, p.R579*	Deletion - Frameshift, Substitution - Nonsense, Unknown	13:48348971-48348971, 13:48453032-48453032, 13:48459687-48459687,	Info_not_available	0.57447, Info_not_available	22941188
RB1	9884	COSM4603936, COSM892,	upper_aerodigestive_tract	carcinoma	p.L158fs*19, p.R579*	Insertion - Frameshift, Substitution - Nonsense	13:48345163-48345164, 13:48453032-48453032,	Info_not_available	0.57447, Info_not_available	25056374
RB1	9884	COSM6842418, COSM892,	skin	carcinoma	p.?, p.R579*	Substitution - Nonsense, Unknown	13:48453032-48453032, 13:48453108-48453111,	Info_not_available	0.57447, Info_not_available	28984303
RB1	9884	COSM892,	eye	retinoblastoma	p.R579*	Substitution - Nonsense	13:48453032-48453032,	Info_not_available	0.57447	15166261
RB1	9884	COSM892,	biliary_tract	carcinoma	p.R579*	Substitution - Nonsense	13:48453032-48453032,	Info_not_available	0.57447	24997986
RB1	9884	COSM1038, COSM1039, COSM886, COSM892, COSM893, COSM894, COSM896, COSM897, COSM898, COSM899, COSM900, COSM901, COSM902,	eye	retinoblastoma	p.E112fs*6, p.E748fs, p.H483fs*9, p.I124fs*6, p.L76fs*1, p.M695fs*10, p.Q62*, p.Q689fs, p.R579*, p.R579fs*29, p.S576fs*34, p.Y529fs*26, p.Y606fs*47	Deletion - Frameshift, Insertion - Frameshift, Substitution - Nonsense	13:48307326-48307326, 13:48307369-48307369, 13:48342670-48342674, 13:48342704-48342705, 13:48380190-48380191, 13:48381333-48381334, 13:48453020-48453023, 13:48453032-48453032, 13:48453032-48453041, 13:48456205-48456206, 13:48459792-48459793, 13:48459811-48459811,	Info_not_available	0.57158, .57447, Info_not_available	9311732
RB1	9884	COSM1051, COSM881,	eye	retinoblastoma	p.?, p.I126S	Substitution - Missense, Unknown	13:48342711-48342711,	Info_not_available	0.55835, Info_not_available	12402348
RB1	9884	COSM1477250, COSM1942249, COSM1942280, COSM1942291, COSM1942343, COSM1942347, COSM1942441, COSM19454, COSM22909, COSM25237, COSM3729848, COSM3955640, COSM432450, COSM4771412, COSM4990381, COSM5231898, COSM5547810, COSM5573885, COSM5676772, COSM5731157, COSM5731162, COSM6908922, COSM6908948, COSM6909161, COSM6909932, COSM6909944, COSM6910011, COSM6910144, COSM6910891, COSM6911104, COSM6911214, COSM6911911, COSM6912331, COSM6913797, COSM6913846, COSM6914648, COSM6914960, COSM6916141, COSM6916386, COSM6916995, COSM6917373, COSM6917575, COSM6919147, COSM6920912, COSM6920976, COSM6921270, COSM6921652, COSM6921799, COSM6923011, COSM6923290, COSM6923452, COSM6923865, COSM6924199, COSM6924529, COSM6925270, COSM6925714, COSM6925804, COSM6925864, COSM6926020, COSM6926201, COSM6926553, COSM6927281, COSM6927723, COSM6927887, COSM6928171, COSM6928307, COSM6928553, COSM6928720, COSM6929263, COSM6930621, COSM6930634, COSM6932689, COSM6932997, COSM6933181, COSM6933728, COSM6934577, COSM6935954, COSM6936156, COSM6936318, COSM6936723, COSM6936992, COSM6937176, COSM6937334, COSM6938278, COSM6938721, COSM6938797, COSM6938872, COSM6938891, COSM6938979, COSM6939055, COSM6939667, COSM6942233, COSM6942888, COSM6943892, COSM6944013, COSM6944153, COSM6944675, COSM6944690, COSM6944925, COSM6945688, COSM6945768, COSM6945974, COSM6947221, COSM6947264, COSM6947779, COSM6948814, COSM6948884, COSM6949457, COSM6949852, COSM6950650, COSM6950690, COSM6950823, COSM6950886, COSM6951147, COSM6951239, COSM6951631, COSM6951677, COSM6952811, COSM6952955, COSM6954527, COSM6955574, COSM6955685, COSM6955766, COSM6956540, COSM6956592, COSM6957961, COSM6958136, COSM6960284, COSM6960392, COSM6961236, COSM6961360, COSM6962032, COSM6962547, COSM6963021, COSM6963299, COSM6963383, COSM6965100, COSM6966805, COSM6966915, COSM6967996, COSM6968169, COSM6968286, COSM6968585, COSM6968741, COSM6969215, COSM6969559, COSM6969592, COSM6970857, COSM6971251, COSM6972181, COSM6972345, COSM6972639, COSM6973390, COSM6973394, COSM6974590, COSM6975067, COSM6977525, COSM6978149, COSM6978469, COSM6978863, COSM6979259, COSM6979867, COSM6981262, COSM6981337, COSM6981674, COSM6982066, COSM6982097, COSM6982493, COSM6982940, COSM6983087, COSM6983099, COSM6984109, COSM6984567, COSM6984693, COSM6985380, COSM6986296, COSM6986632, COSM892, COSM893, COSM923,	NS, adrenal_gland, biliary_tract, bone, breast, central_nervous_system, cervix, endometrium, eye, haematopoietic_and_lymphoid_tissue, kidney, large_intestine, liver, lung, ovary, pancreas, prostate, salivary_gland, skin, small_intestine, soft_tissue, thyroid, upper_aerodigestive_tract, urinary_tract	adnexal_tumour, adrenal_cortical_carcinoma, carcinoma, gastrointestinal_stromal_tumour, glioma, leiomyosarcoma, lymphoid_neoplasm, malignant_fibrous_histiocytoma-pleomorphic_sarcoma, malignant_melanoma, osteosarcoma, other, retinoblastoma, sarcoma	p.?, p.A11fs*20, p.A15fs*3, p.A17fs*3, p.A333fs*13, p.A525fs*7, p.A562fs*49, p.A74fs*4, p.C102fs*7, p.C438fs*19, p.C489fs*5, p.C553fs*58, p.D156fs*19, p.D346fs*4, p.D479fs*16, p.D571fs*41, p.D697fs*23, p.E125fs*11, p.E19*, p.E280_E287delEHECNIDE, p.E287fs*2, p.E466delE, p.E492fs*4, p.E539_T543delEGNLT, p.E667*, p.E693fs*3, p.E72fs*34, p.F299fs*4, p.F514*, p.F514fs*8, p.G100fs*11, p.G38F, p.G423_Y424>E*, p.G449fs*8, p.G540fs*3, p.G617fs*36, p.H281fs*2, p.H483fs*10, p.H555delH, p.I324fs*17, p.I532fs*57, p.I66fs*11, p.I723fs*28, p.I768fs*23, p.I799fs*11, p.K143fs*19, p.K412N, p.K537fs*14, p.K577fs*34, p.K616fs*7, p.K63fs*38, p.K640*, p.K844fs*5, p.K844fs*6, p.L199fs*4, p.L277fs*9, p.L317fs*1, p.L326fs*1, p.L337fs*12, p.L343fs*3, p.L385fs*1, p.L44fs*4, p.L477_D479delLND, p.L486fs*6, p.L487fs*6, p.L564fs*47, p.L60*, p.L647fs*5, p.L649fs*11, p.L670fs*7, p.L743fs*1, p.L76*, p.L769fs*41, p.L76fs*1, p.L809fs*17, p.M148fs*8, p.M386fs*11, p.M460fs*3, p.M484fs*8, p.M761fs*21, p.M825fs*1, p.N123fs*2, p.N133fs*1, p.N258fs*11, p.N328fs*1, p.N328fs*4, p.N472fs*6, p.N522fs*2, p.N593fs*11, p.N623fs*15, p.N627fs*16, p.N803fs*7, p.N854fs*1, p.N867fs*2, p.P250fs*16, p.P253fs*5, p.P28fs*37, p.P609fs*43, p.P732fs*12, p.P793S, p.Q207fs*5, p.Q383fs*3, p.Q62*, p.Q639*, p.Q93*, p.R150fs*7, p.R320fs*12, p.R418fs*9, p.R579*, p.R698fs*22, p.R73fs*36, p.R787*, p.R798fs*4, p.R7fs*24, p.R7fs*58, p.R828fs*10, p.R861fs*12, p.S163N, p.S182fs*2, p.S182fs*3, p.S194fs*7, p.S318fs*13, p.S414fs*14, p.S534_E539>K, p.S648fs*4, p.S816fs*10, p.S842fs*1, p.T140fs*6, p.T497fs*22, p.T625fs*24, p.T841fs*8, p.T9fs*56, p.V291fs*9, p.V450fs*13, p.V654fs*14, p.V654fs*4, p.V754fs*4, p.V81I, p.W563fs*7, p.W78_E79>*, p.W99fs*11, p.W99fs*5, p.Y173fs*11, p.Y239fs*25, p.Y321*, p.Y453fs*1, p.Y529fs*3, p.Y655fs*13, p.Y655fs*3, p.Y771fs*23, p.Y813fs*10	Complex - compound substitution, Complex - deletion inframe, Complex - frameshift, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Substitution - Missense, Substitution - Nonsense, Unknown	13:48303925-48303926, 13:48303926-48303926, 13:48303933-48303933, 13:48303940-48303941, 13:48303945-48303976, 13:48303947-48303984, 13:48303966-48303967, 13:48303991-48303991, 13:48304024-48304025, 13:48304040-48304041, 13:48307321-48307321, 13:48307322-48307347, 13:48307326-48307326, 13:48307337-48307337, 13:48307352-48307353, 13:48307353-48307354, 13:48307356-48307366, 13:48307368-48307368, 13:48307369-48307369, 13:48307376-48307377, 13:48307383-48307383, 13:48342576-48342666, 13:48342611-48342611, 13:48342628-48342629, 13:48342629-48342645, 13:48342630-48342630, 13:48342638-48342639, 13:48342697-48342697, 13:48342707-48342707, 13:48345092-48345093, 13:48345116-48345117, 13:48345126-48345165, 13:48345142-48345143, 13:48345145-48345146, 13:48345167-48345167, 13:48345186-48345201, 13:48345187-48345187, 13:48345192-48345308, 13:48347837-48347838, 13:48348957-48348958, 13:48348997-48348997, 13:48349007-48349008, 13:48359976-48360015, 13:48360015-48360016, 13:48360016-48360016, 13:48360026-48360027, 13:48360125-48360125, 13:48360129-48360178, 13:48362696-48362825, 13:48362843-48362856, 13:48362848-48362866, 13:48362865-48362869, 13:48362926-48362926, 13:48362934-48362957, 13:48362936-48362937, 13:48362950-48362958, 13:48362955-48362955, 13:48364902-48364905, 13:48364926-48364938, 13:48367326-48367563, 13:48367502-48367505, 13:48367502-48367506, 13:48367512-48367512, 13:48367517-48367517, 13:48367522-48367546, 13:48367529-48367530, 13:48367533-48367533, 13:48367533-48367534, 13:48367549-48367558, 13:48367560-48367560, 13:48367579-48367580, 13:48367589-48367596, 13:48373423-48373423, 13:48373428-48373431, 13:48373435-48373447, 13:48376909-48376927, 13:48376938-48376938, 13:48376939-48376940, 13:48376951-48376952, 13:48376965-48377035, 13:48376970-48376974, 13:48377013-48377013, 13:48379584-48379598, 13:48379584-48379614, 13:48379605-48379606, 13:48379606-48379606, 13:48379617-48379626, 13:48379639-48379640, 13:48380053-48380055, 13:48380075-48380075, 13:48380075-48380106, 13:48380077-48380093, 13:48380171-48380180, 13:48380180-48380180, 13:48380184-48380185, 13:48380191-48380192, 13:48380198-48380199, 13:48380204-48380204, 13:48380205-48380208, 13:48380206-48380207, 13:48380225-48380249, 13:48380230-48380230, 13:48380242-48380242, 13:48381287-48381288, 13:48381289-48381290, 13:48381312-48381312, 13:48381317-48381317, 13:48381329-48381329, 13:48381339-48381405, 13:48381349-48381363, 13:48381358-48381419, 13:48381361-48381375, 13:48381366-48381366, 13:48381405-48381405, 13:48381411-48381413, 13:48381427-48381427, 13:48381434-48381439, 13:48381438-48381438, 13:48452973-48453005, 13:48453004-48453005, 13:48453025-48453025, 13:48453031-48453032, 13:48453032-48453032, 13:48453072-48453093, 13:48456209-48456210, 13:48456231-48456232, 13:48456237-48456238, 13:48456254-48456269, 13:48456261-48456276, 13:48456267-48456267, 13:48456303-48456304, 13:48456306-48456307, 13:48456324-48456325, 13:48456328-48456329, 13:48456329-48456330, 13:48456342-48456343, 13:48456343-48456343, 13:48459679-48459723, 13:48459687-48459702, 13:48459689-48459689, 13:48459689-48459690, 13:48459726-48459726, 13:48459735-48459735, 13:48459806-48459807, 13:48459812-48459813, 13:48459819-48459820, 13:48463787-48463788, 13:48463816-48463816, 13:48463816-48463846, 13:48463817-48463838, 13:48464996-48464997, 13:48464997-48464998, 13:48465011-48465011, 13:48465043-48465044, 13:48465068-48465105, 13:48465088-48465098, 13:48465089-48465089, 13:48465097-48465098, 13:48465204-48465204, 13:48465237-48465238, 13:48465241-48465242, 13:48465256-48465256, 13:48465272-48465272, 13:48465283-48465283, 13:48465305-48465305, 13:48465316-48465325, 13:48465323-48465323, 13:48465348-48465348, 13:48465357-48465358, 13:48465370-48465370, 13:48473388-48473388, 13:48476476-48476740, 13:48476704-48476705, 13:48476706-48476707, 13:48476710-48476710, 13:48476738-48476739, 13:48476758-48476758, 13:48476778-48476782, 13:48476835-48476849,	Info_not_available	0.54614, .57158, .57447, .59537, .59579, .61851, .62559, .62893, .63765, .66824, .67177, Info_not_available	28481359
RB1	9884	COSM6494235, COSM6494237,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A15T, p.A16_A18delAAA	Deletion - In frame, Substitution - Missense	13:48303949-48303957, 13:48303955-48303955,	Info_not_available	0.52966, Info_not_available	27534895
RB1	9884	COSM1367193, COSM5586384, COSM5610456, COSM5610473, COSM892,	skin	malignant_melanoma	p.F650fs*5, p.G248G, p.G802G, p.R320L, p.R579*	Deletion - Frameshift, Substitution - Missense, Substitution - Nonsense, Substitution - coding silent	13:48362840-48362840, 13:48367513-48367513, 13:48453032-48453032, 13:48456339-48456348, 13:48465285-48465285,	Info_not_available	0.5244, .57447, .60393, .69704, Info_not_available	26343386