Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PTPRM	9675	COSM5009499,	large_intestine	carcinoma	p.E1238K	Substitution - Missense	18:8379305-8379305,	PATHOGENIC	0.99157	24951259
PTPRM	9675	COSM314597,	lung	carcinoma	p.M1408I	Substitution - Missense	18:8394530-8394530,	PATHOGENIC	0.99117	22941188
PTPRM	9675	COSM304544,	large_intestine	carcinoma	p.C642Y	Substitution - Missense	18:8113554-8113554,	PATHOGENIC	0.98951	21892161
PTPRM	9675	COSM284384,	large_intestine	carcinoma	p.E91*	Substitution - Nonsense	18:7888180-7888180,	PATHOGENIC	0.98839	24951259
PTPRM	9675	COSM5009438,	large_intestine	carcinoma	p.G1393E	Substitution - Missense	18:8394484-8394484,	PATHOGENIC	0.98599	24951259
PTPRM	9675	COSM314596,	lung	carcinoma	p.L1276P	Substitution - Missense	18:8380375-8380375,	PATHOGENIC	0.97147	22941188
PTPRM	9675	COSM39745,	central_nervous_system	glioma	p.M1220V	Substitution - Missense	18:8379251-8379251,	PATHOGENIC	0.96942	18772396
PTPRM	9675	COSM5009306,	large_intestine	carcinoma	p.K635Q	Substitution - Missense	18:8113532-8113532,	PATHOGENIC	0.96215	24951259
PTPRM	9675	COSM3147752,	large_intestine	carcinoma	p.F907F	Substitution - coding silent	18:8296373-8296373,	PATHOGENIC	0.88252	24951259
PTPRM	9675	COSM5009514,	large_intestine	carcinoma	p.R467Q	Substitution - Missense	18:8069953-8069953,	PATHOGENIC	0.8542	24951259
PTPRM	9675	COSM5009308,	large_intestine	carcinoma	p.R1117S	Substitution - Missense	18:8376525-8376525,	PATHOGENIC	0.85021	24951259
PTPRM	9675	COSM1263497,	large_intestine	carcinoma	p.R226Q	Substitution - Missense	18:7949194-7949194,	PATHOGENIC	0.84461	24951259
PTPRM	9675	COSM990150,	large_intestine	carcinoma	p.R394W	Substitution - Missense	18:8069733-8069733,	PATHOGENIC	0.82377	24951259
PTPRM	9675	COSM5009304,	large_intestine	carcinoma	p.R399R	Substitution - coding silent	18:8069750-8069750,	PATHOGENIC	0.81506	24951259
PTPRM	9675	COSM5010138,	large_intestine	carcinoma	p.V283V	Substitution - coding silent	18:7955131-7955131,	PATHOGENIC	0.73336	24951259
PTPRM	9675	COSM5009907,	large_intestine	carcinoma	p.A9T	Substitution - Missense	18:7567843-7567843,	NEUTRAL	0.45115	24951259
PTPRM	9675	COSM5008486,	large_intestine	carcinoma	p.I1235I	Substitution - coding silent	18:8379298-8379298,	NEUTRAL	0.16029	24951259
PTPRM	9675	COSM4000474,	large_intestine	carcinoma	p.N439N	Substitution - coding silent	18:8069870-8069870,	NEUTRAL	0.07897	24951259
PTPRM	9675	COSM4995816,	upper_aerodigestive_tract	carcinoma	p.Y898*	Substitution - Nonsense	18:8253393-8253393,	Info_not_available	0.52855	24952746