Gene Name HGNC ID COSMIC_MutID Primary sitePrimary histology AA-Mutation Mutation Type Genomic PositionFATHMM predictionFATHMM scoreLiterature evidence
MYC7553COSM5656309, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59ASubstitution - Missense8:127738437-127738437, PATHOGENIC0.9948227276561
MYC7553COSM5656309, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59ASubstitution - Missense8:127738437-127738437, PATHOGENIC0.9948227276561
MYC7553COSM5656309, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59ASubstitution - Missense8:127738437-127738437, PATHOGENIC0.9948227276561
MYC7553COSM5945172, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59RSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9948227276561
MYC7553COSM5945172, lungcarcinomap.P59RSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9948228481359
MYC7553COSM5656309, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59ASubstitution - Missense8:127738437-127738437, PATHOGENIC0.9948227276561
MYC7553COSM3316882, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.T58NSubstitution - Missense8:127738435-127738435, PATHOGENIC0.9947627276561
MYC7553COSM3316882, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.T58NSubstitution - Missense8:127738435-127738435, PATHOGENIC0.9947627276561
MYC7553COSM4171758, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59TSubstitution - Missense8:127738437-127738437, PATHOGENIC0.9946827276561
MYC7553COSM4171758, endometriumcarcinomap.P59TSubstitution - Missense8:127738437-127738437, PATHOGENIC0.9946828481359
MYC7553COSM5424189, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59QSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9946827276561
MYC7553COSM5424189, salivary_glandcarcinomap.P59QSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9946828481359
MYC7553COSM3316884, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P60TSubstitution - Missense8:127738440-127738440, PATHOGENIC0.9946827276561
MYC7553COSM3316888, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P60HSubstitution - Missense8:127738441-127738441, PATHOGENIC0.9946827276561
MYC7553COSM5424189, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59QSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9946829386642
MYC7553COSM5424189, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59QSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9946827276561
MYC7553COSM5424189, salivary_glandcarcinomap.P59QSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9946828481359
MYC7553COSM5424189, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59QSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9946827276561
MYC7553COSM6949801, NScarcinomap.P63LSubstitution - Missense8:127738450-127738450, PATHOGENIC0.9944328481359
MYC7553COSM48581, lungcarcinomap.S250ISubstitution - Missense8:127739011-127739011, PATHOGENIC0.9943918948947
MYC7553COSM1286404, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.T58ISubstitution - Missense8:127738435-127738435, PATHOGENIC0.9943228481359
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942327276561
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942327276561
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942327276561
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942322976956
MYC7553COSM4993048, skincarcinomap.S62FSubstitution - Missense8:127738447-127738447, PATHOGENIC0.9942325589618
MYC7553COSM5945174, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P60SSubstitution - Missense8:127738440-127738440, PATHOGENIC0.9942327276561
MYC7553COSM5945176, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P60LSubstitution - Missense8:127738441-127738441, PATHOGENIC0.9942327276561
MYC7553COSM1166664, lungcarcinomap.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942328481359
MYC7553COSM5945174, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P60SSubstitution - Missense8:127738440-127738440, PATHOGENIC0.9942327276561
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942327276561
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942327276561
MYC7553COSM1166664, skinmalignant_melanomap.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942326343386
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942327276561
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942327276561
MYC7553COSM1161731, lungcarcinomap.P59SSubstitution - Missense8:127738437-127738437, PATHOGENIC0.9942328481359
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942324030381
MYC7553COSM1166664, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P59LSubstitution - Missense8:127738438-127738438, PATHOGENIC0.9942327276561
MYC7553COSM3316878, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.P57TSubstitution - Missense8:127738431-127738431, PATHOGENIC0.9928728481359
MYC7553COSM6982948, large_intestinecarcinomap.A310TSubstitution - Missense8:127740566-127740566, PATHOGENIC0.9921328481359
MYC7553COSM5945170, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P57LSubstitution - Missense8:127738432-127738432, PATHOGENIC0.9920327276561
MYC7553COSM3316880, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.P57SSubstitution - Missense8:127738431-127738431, PATHOGENIC0.9920328481359
MYC7553COSM6938424, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.E257QSubstitution - Missense8:127740407-127740407, PATHOGENIC0.9916628481359
MYC7553COSM6947110, breastcarcinomap.E257*Substitution - Nonsense8:127740407-127740407, PATHOGENIC0.9913928481359
MYC7553COSM4171790, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.D258NSubstitution - Missense8:127740410-127740410, PATHOGENIC0.9910524030381
MYC7553COSM4605973, upper_aerodigestive_tractcarcinomap.D263HSubstitution - Missense8:127740425-127740425, PATHOGENIC0.9906125056374
MYC7553COSM749416, prostatecarcinomap.Q306ESubstitution - Missense8:127740554-127740554, PATHOGENIC0.990328481359
MYC7553COSM6927342, large_intestinecarcinomap.S252YSubstitution - Missense8:127739017-127739017, PATHOGENIC0.9890328481359
MYC7553COSM1163491, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.T58ASubstitution - Missense8:127738434-127738434, PATHOGENIC0.9886828481359
MYC7553COSM6978791, large_intestinecarcinomap.E259KSubstitution - Missense8:127740413-127740413, PATHOGENIC0.9886728481359
MYC7553COSM5652696, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.H307YSubstitution - Missense8:127740557-127740557, PATHOGENIC0.9885128481359
MYC7553COSM1159798, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.A44VSubstitution - Missense8:127738393-127738393, PATHOGENIC0.9880327276561
MYC7553COSM1159798, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.A44VSubstitution - Missense8:127738393-127738393, PATHOGENIC0.9880327276561
MYC7553COSM1159798, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.A44VSubstitution - Missense8:127738393-127738393, PATHOGENIC0.9880327276561
MYC7553COSM1159798, endometriumcarcinomap.A44VSubstitution - Missense8:127738393-127738393, PATHOGENIC0.9880328481359
MYC7553COSM6961422, upper_aerodigestive_tractcarcinomap.S18LSubstitution - Missense8:127738315-127738315, PATHOGENIC0.9879728481359
MYC7553COSM1454793, ovarycarcinomap.S146LSubstitution - Missense8:127738699-127738699, PATHOGENIC0.9878628481359
MYC7553COSM1454793, endometriumcarcinomap.S146LSubstitution - Missense8:127738699-127738699, PATHOGENIC0.9878628481359
MYC7553COSM1454793, large_intestinecarcinomap.S146LSubstitution - Missense8:127738699-127738699, PATHOGENIC0.9878628481359
MYC7553COSM1454793, skincarcinomap.S146LSubstitution - Missense8:127738699-127738699, PATHOGENIC0.9878628481359
MYC7553COSM1454793, small_intestinecarcinomap.S146LSubstitution - Missense8:127738699-127738699, PATHOGENIC0.9878628481359
MYC7553COSM6955866, lungcarcinomap.E351KSubstitution - Missense8:127740689-127740689, PATHOGENIC0.9871928481359
MYC7553COSM6914554, prostatecarcinomap.N360TSubstitution - Missense8:127740717-127740717, PATHOGENIC0.9868228481359
MYC7553COSM6955478, kidneycarcinomap.A150SSubstitution - Missense8:127738710-127738710, PATHOGENIC0.9865928481359
MYC7553COSM1096012, stomachcarcinomap.H359RSubstitution - Missense8:127740714-127740714, PATHOGENIC0.9861126489445
MYC7553COSM1096012, endometriumcarcinomap.H359RSubstitution - Missense8:127740714-127740714, PATHOGENIC0.9861128481359
MYC7553COSM6920082, large_intestinecarcinomap.K143TSubstitution - Missense8:127738690-127738690, PATHOGENIC0.9851628481359
MYC7553COSM5763069, urinary_tractcarcinomap.S139LSubstitution - Missense8:127738678-127738678, PATHOGENIC0.9841728481359
MYC7553COSM4384396, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.C438SSubstitution - Missense8:127740951-127740951, PATHOGENIC0.9830424030381
MYC7553COSM3316990, urinary_tractcarcinomap.C300YSubstitution - Missense8:127740537-127740537, PATHOGENIC0.9821728481359
MYC7553COSM6928957, central_nervous_systemgliomap.P313LSubstitution - Missense8:127740576-127740576, PATHOGENIC0.9811128481359
MYC7553COSM6930943, salivary_glandcarcinomap.V296FSubstitution - Missense8:127740524-127740524, PATHOGENIC0.9809328481359
MYC7553COSM6549728, urinary_tractcarcinomap.S226LSubstitution - Missense8:127738939-127738939, PATHOGENIC0.9786828481359
MYC7553COSM6928783, lungcarcinomap.R65CSubstitution - Missense8:127738455-127738455, PATHOGENIC0.9781228481359
MYC7553COSM6718708, oesophaguscarcinomap.E29DSubstitution - Missense8:127738349-127738349, PATHOGENIC0.976928481359
MYC7553COSM6917286, breastcarcinomap.I116NSubstitution - Missense8:127738609-127738609, PATHOGENIC0.9754828481359
MYC7553COSM5019918, soft_tissuehaemangioblastomap.N11SSubstitution - Missense8:127738294-127738294, PATHOGENIC0.9753625589003
MYC7553COSM5019918, soft_tissuehaemangioblastomap.N11SSubstitution - Missense8:127738294-127738294, PATHOGENIC0.9753625589003
MYC7553COSM6961804, small_intestinecarcinomap.S230FSubstitution - Missense8:127738951-127738951, PATHOGENIC0.974928481359
MYC7553COSM6918134, lungcarcinomap.V361LSubstitution - Missense8:127740719-127740719, PATHOGENIC0.9731528481359
MYC7553COSM6985373, urinary_tractcarcinomap.V330LSubstitution - Missense8:127740626-127740626, PATHOGENIC0.9689928481359
MYC7553COSM6910805, central_nervous_systemgliomap.P245SSubstitution - Missense8:127738995-127738995, PATHOGENIC0.9674528481359
MYC7553COSM6930925, ovarycarcinomap.S71LSubstitution - Missense8:127738474-127738474, PATHOGENIC0.9665828481359
MYC7553COSM4171794, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.S373RSubstitution - Missense8:127740757-127740757, PATHOGENIC0.9655328481359
MYC7553COSM4767648, biliary_tractcarcinomap.R364CSubstitution - Missense8:127740728-127740728, PATHOGENIC0.9627124997986
MYC7553COSM6938416, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.E39ASubstitution - Missense8:127738378-127738378, PATHOGENIC0.9626728481359
MYC7553COSM6926817, skincarcinomap.A376VSubstitution - Missense8:127740765-127740765, PATHOGENIC0.9622728481359
MYC7553COSM3316954, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.S203NSubstitution - Missense8:127738870-127738870, PATHOGENIC0.9545928481359
MYC7553COSM6944059, skincarcinomap.L297FSubstitution - Missense8:127740527-127740527, PATHOGENIC0.9512728481359
MYC7553COSM6930656, endometriumcarcinomap.G88SSubstitution - Missense8:127738524-127738524, PATHOGENIC0.9417428481359
MYC7553COSM6986998, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.L224VSubstitution - Missense8:127738932-127738932, PATHOGENIC0.9408528481359
MYC7553COSM3316916, urinary_tractcarcinomap.G108ESubstitution - Missense8:127738585-127738585, PATHOGENIC0.9396928481359
MYC7553COSM6978977, livercarcinomap.H429YSubstitution - Missense8:127740923-127740923, PATHOGENIC0.9372428481359
MYC7553COSM3896694, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.G90DSubstitution - Missense8:127738531-127738531, PATHOGENIC0.9356628481359
MYC7553COSM3778899, lungcarcinomap.F7LSubstitution - Missense8:127738283-127738283, PATHOGENIC0.926528481359
MYC7553COSM6987115, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.Q37RSubstitution - Missense8:127738372-127738372, PATHOGENIC0.9238128481359
MYC7553COSM6958018, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.P237SSubstitution - Missense8:127738971-127738971, PATHOGENIC0.9228328481359
MYC7553COSM6915924, large_intestinecarcinomap.A183TSubstitution - Missense8:127738809-127738809, PATHOGENIC0.9219928481359
MYC7553COSM6938422, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.P205SSubstitution - Missense8:127738875-127738875, PATHOGENIC0.9196428481359
MYC7553COSM96060, lungcarcinomap.Q380QSubstitution - coding silent8:127740778-127740778, PATHOGENIC0.9172120668451
MYC7553COSM4993050, skincarcinomap.S314SSubstitution - coding silent8:127740580-127740580, PATHOGENIC0.9141325589618
MYC7553COSM6958016, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.F216LSubstitution - Missense8:127738910-127738910, PATHOGENIC0.9098728481359
MYC7553COSM6969551, ovarycarcinomap.R356WSubstitution - Missense8:127740704-127740704, PATHOGENIC0.8976428481359
MYC7553COSM5472500, skincarcinomap.R435WSubstitution - Missense8:127740941-127740941, PATHOGENIC0.8967728481359
MYC7553COSM6976998, lungcarcinomap.P119ASubstitution - Missense8:127738617-127738617, PATHOGENIC0.8941928481359
MYC7553COSM6975940, lungcarcinomap.V19LSubstitution - Missense8:127738317-127738317, PATHOGENIC0.8827928481359
MYC7553COSM6975940, lungcarcinomap.V19LSubstitution - Missense8:127738317-127738317, PATHOGENIC0.8827928481359
MYC7553COSM6915926, large_intestinecarcinomap.R435QSubstitution - Missense8:127740942-127740942, PATHOGENIC0.8721828481359
MYC7553COSM6936277, lungcarcinomap.P72SSubstitution - Missense8:127738476-127738476, PATHOGENIC0.8649928481359
MYC7553COSM6964439, large_intestinecarcinomap.A321TSubstitution - Missense8:127740599-127740599, PATHOGENIC0.8463228481359
MYC7553COSM6914624, lungcarcinomap.E122DSubstitution - Missense8:127738628-127738628, PATHOGENIC0.8433628481359
MYC7553COSM6938420, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.T95ASubstitution - Missense8:127738545-127738545, PATHOGENIC0.8365528481359
MYC7553COSM6934772, skinmalignant_melanomap.S437FSubstitution - Missense8:127740948-127740948, PATHOGENIC0.8251628481359
MYC7553COSM6934772, skinmalignant_melanomap.S437FSubstitution - Missense8:127740948-127740948, PATHOGENIC0.8251628481359
MYC7553COSM6934772, lungcarcinomap.S437FSubstitution - Missense8:127740948-127740948, PATHOGENIC0.8251628481359
MYC7553COSM6928078, urinary_tractcarcinomap.S204ASubstitution - Missense8:127738872-127738872, PATHOGENIC0.8123328481359
MYC7553COSM6959140, large_intestinecarcinomap.N86SSubstitution - Missense8:127738519-127738519, PATHOGENIC0.8113428481359
MYC7553COSM6934523, breastcarcinomap.G285ESubstitution - Missense8:127740492-127740492, PATHOGENIC0.8097128481359
MYC7553COSM6938418, haematopoietic_and_lymphoid_tissuelymphoid_neoplasmp.D85ESubstitution - Missense8:127738517-127738517, PATHOGENIC0.7917728481359
MYC7553COSM6981632, prostatecarcinomap.R423GSubstitution - Missense8:127740905-127740905, PATHOGENIC0.7858128481359
MYC7553COSM5575846, stomachcarcinomap.A439VSubstitution - Missense8:127740954-127740954, PATHOGENIC0.7562626489445
MYC7553COSM5575846, skinmalignant_melanomap.A439VSubstitution - Missense8:127740954-127740954, PATHOGENIC0.7562626343386
MYC7553COSM6936367, lungcarcinomap.A165SSubstitution - Missense8:127738755-127738755, PATHOGENIC0.7211728481359
MYC7553COSM4384394, haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasmp.P282ASubstitution - Missense8:127740482-127740482, NEUTRAL0.4427724030381
MYC7553COSM6954235, breastcarcinomap.I262MSubstitution - Missense8:127740424-127740424, NEUTRAL0.4013828481359
MYC7553COSM5019469, soft_tissuehaemangioblastomap.P231PSubstitution - coding silent8:127738955-127738955, NEUTRAL0.3194625589003
MYC7553COSM5019469, soft_tissuehaemangioblastomap.P231PSubstitution - coding silent8:127738955-127738955, NEUTRAL0.3194625589003
MYC7553COSM5019469, soft_tissuehaemangioblastomap.P231PSubstitution - coding silent8:127738955-127738955, NEUTRAL0.3194625589003
MYC7553COSM5609470, skinmalignant_melanomap.L413LSubstitution - coding silent8:127740877-127740877, NEUTRAL0.2903426343386
MYC7553COSM48978, lungcarcinomap.S234_P235>TComplex - deletion inframe8:127738963-127738965, Info_not_availableInfo_not_available18948947
MYC7553COSM317654, lungcarcinomap.K392fs*2Deletion - Frameshift8:127740807-127740807, Info_not_availableInfo_not_available22941188
MYC7553COSM4704354, breastcarcinomap.Q37delQDeletion - In frame8:127738359-127738361, Info_not_availableInfo_not_available25850943
MYC7553COSM5079114, COSM6924447, COSM6928353, COSM6945313, COSM6953433, COSM6958036, COSM6958038, COSM6968645, COSM6980543, COSM6981441, COSM6982187, COSM6987009, NS, breast, haematopoietic_and_lymphoid_tissue, large_intestine, lung, pancreas, salivary_gland, soft_tissueangiosarcoma, carcinoma, lymphoid_neoplasmp.?, p.C171S, p.C171Y, p.E29delE, p.L144Y, p.N86delN, p.P57F, p.P57L, p.Q37_S38insQ, p.S283delS, p.T8delT, p.Y177_L178>HQComplex - compound substitution, Deletion - In frame, Insertion - In frame, Substitution - Missense, Unknown8:127738283-127738285, 8:127738341-127738343, 8:127738358-127738359, 8:127738431-127738432, 8:127738432-127738433, 8:127738516-127738518, 8:127738692-127738693, 8:127738773-127738773, 8:127738774-127738774, 8:127738791-127738795, 8:127740370-127740510, 8:127740483-127740485, Info_not_available0.591, .65339, Info_not_available28481359