Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
ARRB2	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	17620599	0.35	BioGRID, IntAct
ATM	Affinity Capture-Western	physical	21606198	NA	BioGRID
BBS10	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT
BCL10	Affinity Capture-Western	physical	17189706	NA	BioGRID
BST2	Affinity Capture-Western	physical	23221546	NA	BioGRID
CARD11	Affinity Capture-Western	physical	18625728, 20164171, 27497262	NA	BioGRID
CARD8	Affinity Capture-MS	physical	26186194, 28514442	NA	BioGRID
CARNMT1	Affinity Capture-MS	physical	26186194, 28514442	NA	BioGRID
CCDC102B	Affinity Capture-MS	physical	28514442	NA	BioGRID
CDC37	Affinity Capture-Western, anti bait coimmunoprecipitation, pull down, tandem affinity purification	association, physical, physical association	14743216, 19026643	0.62	BioGRID, IntAct, MINT
CHUK	Affinity Capture-Western, Co-localization, coimmunoprecipitation, proximity ligation assay	association, physical, physical association	10094049, 10187861, 16893890, 20200282, 25241761, 9742107	0.56	BioGRID, IntAct, MINT
CLTC	Co-localization, proximity ligation assay, tandem affinity purification	physical, physical association	14743216, 25241761	0.40	BioGRID, IntAct
COPS5	Two-hybrid, two hybrid pooling approach	physical, physical association	20936779	0.37	BioGRID, IntAct
CRBN	Affinity Capture-Western	physical	27468689	NA	BioGRID
CYLD	Affinity Capture-MS, Affinity Capture-Western	physical	18332137, 27591049	NA	BioGRID
DAAM1	Affinity Capture-MS	physical	21903422	NA	BioGRID
DAZAP2	Affinity Capture-Western	physical	18762249	NA	BioGRID
DR1	Affinity Capture-Western	physical	18838386	NA	BioGRID
ECSIT	Affinity Capture-Western	physical	25371197	NA	BioGRID
EDARADD	Affinity Capture-Western	physical	16251197	NA	BioGRID
EIF2AK2	Affinity Capture-Western	physical	12609980	NA	BioGRID
ELP1	Affinity Capture-Western	physical	10094049	NA	BioGRID
EMILIN1	Affinity Capture-MS	physical	28514442	NA	BioGRID
ERC1	Affinity Capture-Western	physical	20932476	NA	BioGRID
EZH2	Two-hybrid	physical	21900206	NA	BioGRID
FBXL17	Affinity Capture-MS	physical	27234298	NA	BioGRID
FBXW5	Affinity Capture-MS, Affinity Capture-Western	physical	19232515	NA	BioGRID
FYB1	Affinity Capture-Western	physical	20164171	NA	BioGRID
HCFC1	Co-fractionation	physical	22939629	NA	BioGRID
HGS	Reconstituted Complex	physical	11397816	NA	BioGRID
HIPK2	Biochemical Activity, anti bait coimmunoprecipitation	association, physical	15082531, 23565059	0.35	BioGRID, IntAct
HSP90AA1	Affinity Capture-Western, anti bait coimmunoprecipitation, pull down, tandem affinity purification	association, physical, physical association	14743216, 19026643	0.62	BioGRID, IntAct, MINT
HSPA1L	Co-localization, proximity ligation assay, tandem affinity purification	physical, physical association	14743216, 25241761	0.40	BioGRID, IntAct
HSPB1	Affinity Capture-Western	physical	24686082	NA	BioGRID
HSPBP1	Affinity Capture-MS	physical	28514442	NA	BioGRID
IFIT5	Affinity Capture-Western	physical	26334375	NA	BioGRID
IKBKB	Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation	physical, physical association	10807933, 17363905, 17363973, 18316610, 18456659, 20932476, 21331078, 24270572, 25946971, 26334375, 27387502	0.40	BioGRID, IntAct, MINT
IKBKG	Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation	physical, physical association	17363973, 19531477, 21606198, 23986494	0.40	BioGRID, IntAct, MINT
IL17RA	Affinity Capture-Western	physical	17277779	NA	BioGRID
IL17RC	Affinity Capture-MS	physical	28514442	NA	BioGRID
IL17RD	Affinity Capture-Western	physical	23770285	NA	BioGRID
IRAK1	Affinity Capture-Western	physical	12242293, 17197697, 19026643, 23244239	NA	BioGRID
ITCH	Affinity Capture-Western	physical	25632008	NA	BioGRID
KAT2A	Affinity Capture-MS, Affinity Capture-Western	physical	18838386	NA	BioGRID
KERA	Affinity Capture-MS	physical	28514442	NA	BioGRID
MAGED1	Affinity Capture-Western	physical	24947323	NA	BioGRID
MALT1	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	17948050, 25748427	0.40	BioGRID, IntAct, MINT
MAP2K4	Affinity Capture-Western, Biochemical Activity	physical	12429732, 12556533	NA	BioGRID
MAP2K6	Affinity Capture-Western, Biochemical Activity	physical	10094049, 10702308, 10838074, 11460167, 12242293, 12556533, 12609980, 12624112, 14633987, 15590691, 15764709, 16893890, 17079228, 17363905, 17363973, 17384642, 19675569, 20932476, 23606331, 23825189, 26038599	NA	BioGRID
MAP2K7	Co-localization, anti tag coimmunoprecipitation, molecular sieving, proximity ligation assay	physical, physical association	17110930, 17709393, 25241761	0.70	BioGRID, IntAct, MINT
MAP3K14	Affinity Capture-Western, coimmunoprecipitation	physical, physical association	10094049, 10807933	0.40	BioGRID, IntAct, MINT
MAP3K3	Affinity Capture-Western, Two-hybrid	physical	16260783, 19843958	NA	BioGRID
MAP3K5	Affinity Capture-Western, Two-hybrid	physical	10921914, 22167179	NA	BioGRID
MAP3K7	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, tandem affinity purification	physical, physical association	10702308, 12624112, 14743216, 19232515, 20538596, 21817100, 27497262, 9556573, 9742107	0.40	BioGRID, IntAct
MAP4K1	Affinity Capture-Western	physical	10224067	NA	BioGRID
MAPK6	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT
MAPK8	Affinity Capture-Western, Reconstituted Complex, molecular sieving	physical, physical association	11865055, 17709393	0.40	BioGRID, IntAct
MAPK8IP1	Affinity Capture-Western, Co-fractionation, anti bait coimmunoprecipitation, molecular sieving, pull down	association, physical, physical association	16840345, 17709393, 18286207	0.72	BioGRID, IntAct, MINT
MAVS	Affinity Capture-Western	physical	16153868	NA	BioGRID
MCM2	Affinity Capture-MS	physical	25963833	NA	BioGRID
MED4	Affinity Capture-MS	physical	25281560	NA	BioGRID
MIB2	Affinity Capture-Western	physical	21896478	NA	BioGRID
MUL1	Reconstituted Complex	physical	27082251	NA	BioGRID
MYD88	Phenotypic Suppression	genetic	11544529	NA	BioGRID
NAIP	Affinity Capture-Western, Reconstituted Complex	physical	11865055	NA	BioGRID
NDFIP1	Affinity Capture-MS, Affinity Capture-Western	physical	25632008	NA	BioGRID
NDUFS6	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT
NFKBIA	Biochemical Activity	physical	15327770	NA	BioGRID
NLK	Affinity Capture-Western, Co-localization, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, proximity ligation assay	association, physical, physical association	15764709, 20194509, 25241761	0.62	BioGRID, IntAct
NOD2	Affinity Capture-Western, Reconstituted Complex	physical	15075345, 17348859, 17965022	NA	BioGRID
PCDH20	Affinity Capture-MS	physical	28514442	NA	BioGRID
PDPK1	Affinity Capture-Western	physical	26432169	NA	BioGRID
PELI3	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	12874243, 15917247, 18326498	0.40	BioGRID, IntAct
PINK1	Affinity Capture-Western, Biochemical Activity	physical	22643835	NA	BioGRID
POLE4	Co-fractionation	physical	22939629	NA	BioGRID
PPM1B	Affinity Capture-Western, Reconstituted Complex	physical	11104763	NA	BioGRID
PPM1L	Affinity Capture-Western, Biochemical Activity	physical	12556533	NA	BioGRID
PPP2R1A	Biochemical Activity	physical	17079228	NA	BioGRID
PPP5C	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT
PPP6C	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, phosphatase assay	dephosphorylation reaction, physical, physical association	17079228, 19955178	0.60	BioGRID, IntAct, MINT
PRKAA1	Affinity Capture-Western, Biochemical Activity	physical	20538596, 20615388	NA	BioGRID
PRKAB1	Biochemical Activity	physical	20538596	NA	BioGRID
PRKCQ	Affinity Capture-Western	physical	17363905, 20164171	NA	BioGRID
PRMT2	Affinity Capture-MS	physical	26186194	NA	BioGRID
PSMC3	Affinity Capture-MS	physical	26186194, 28514442	NA	BioGRID
RACK1	Affinity Capture-Western	physical	26038599	NA	BioGRID
RBCK1	Affinity Capture-Western	physical	17449468	NA	BioGRID
RBM7	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
RBX1	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT
RELA	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
RIPK1	Affinity Capture-Western, Co-fractionation	physical	16543241, 18570872, 21606198, 24434549	NA	BioGRID
RIPK2	Affinity Capture-Western	physical	17348859, 17947236, 17965022, 18079694	NA	BioGRID
RNF19A	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT
RNF4	Affinity Capture-MS, Affinity Capture-Western	physical	26299341	NA	BioGRID
ROR2	Affinity Capture-Western, Biochemical Activity	physical	18762249	NA	BioGRID
RUVBL1	Co-localization, proximity ligation assay, tandem affinity purification	physical, physical association	14743216, 25241761	0.40	BioGRID, IntAct
SASH1	Affinity Capture-Western	physical	23776175	NA	BioGRID
SCRN1	Affinity Capture-MS	physical	28514442	NA	BioGRID
SGF29	Affinity Capture-Western	physical	18838386	NA	BioGRID
SIK1	Affinity Capture-MS, Affinity Capture-Western	physical	24061540	NA	BioGRID
SIK3	Affinity Capture-MS, Affinity Capture-Western	physical	24061540	NA	BioGRID
SIVA1	Affinity Capture-Western	physical	19584092	NA	BioGRID
SKIL	Affinity Capture-Western	physical	17276978	NA	BioGRID
SMAD3	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
SMAD6	Affinity Capture-Western	physical	10748100, 11737269	NA	BioGRID
SMAD7	Affinity Capture-Western	physical	12589052	NA	BioGRID
SOCS3	Affinity Capture-Western	physical	16543409	NA	BioGRID
STAT3	Affinity Capture-MS, Affinity Capture-Western	physical	15764709	NA	BioGRID
STRADB	Affinity Capture-Western	physical	12048196	NA	BioGRID
STUB1	Affinity Capture-Western	physical	23322406	NA	BioGRID
SYK	Affinity Capture-Western	physical	23962979	NA	BioGRID
SYNC	Affinity Capture-MS	physical	28514442	NA	BioGRID
TAB1	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-fractionation, Co-localization, Phenotypic Enhancement, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, proximity ligation assay, tandem affinity purification, two hybrid	association, genetic, physical, physical association	10094049, 10702308, 10838074, 12242293, 12429732, 12624112, 12975377, 14670075, 14743216, 15590691, 16260783, 16845370, 18456659, 19026643, 19232515, 19556242, 20200282, 20538596, 21903422, 22158122, 22167179, 23934659, 24912525, 25241761, 26432169, 27468689, 27880917, 8638164	0.40, 0.56, 0.73	BioGRID, IntAct, MINT
TAB2	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification	association, physical, physical association	10882101, 11259596, 12242293, 12609980, 14633987, 14670075, 14743216, 16603398, 16845370, 17158449, 17384642, 18021073, 19026643, 19232515, 19556242, 19955178, 20194509, 20200282, 20538596, 21903422, 22081109, 22158122, 22167179, 24061540, 24912525, 25642820, 26432169, 27426733, 27468689, 8638164	0.40, 0.56, 0.84	BioGRID, IntAct, MINT
TAB3	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification	association, physical, physical association	14633987, 14670075, 14743216, 17384642, 18021073, 19232515, 21903422, 22081109, 24912525, 27497262	0.40, 0.62	BioGRID, IntAct, MINT
TADA3	Affinity Capture-Western	physical	18838386	NA	BioGRID
TAOK1	Affinity Capture-Western	physical	16893890	NA	BioGRID
TAOK2	Affinity Capture-Western	physical	16893890	NA	BioGRID
TBL1Y	Affinity Capture-MS	physical	28514442	NA	BioGRID
TGFBR1	Affinity Capture-Western	physical	18758450, 19556242, 23973329	NA	BioGRID
TGFBR2	Affinity Capture-Western	physical	19556242	NA	BioGRID
TH	Affinity Capture-MS	physical	28514442	NA	BioGRID
THBS3	Affinity Capture-MS	physical	28514442	NA	BioGRID
TIRAP	Affinity Capture-Western, Phenotypic Suppression	genetic, physical	11544529, 24084649	NA	BioGRID
TLR3	Affinity Capture-Western	physical	12609980, 16115877	NA	BioGRID
TNF	Affinity Capture-Western	physical	16603398	NA	BioGRID
TNFRSF11A	Affinity Capture-Western	physical	11809792	NA	BioGRID
TNFRSF1A	Affinity Capture-Western	physical	16115877, 16260783, 18037881, 18949366, 21331078	NA	BioGRID
TNIK	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation	association, physical, physical association	22904686	0.50	BioGRID, IntAct
TRAF2	Affinity Capture-Western, tandem affinity purification	physical, physical association	14633987, 14743216, 17384642, 26299341	0.40	BioGRID, IntAct
TRAF3	Affinity Capture-Western, Biochemical Activity	physical	26882989	NA	BioGRID
TRAF3IP2	Affinity Capture-Western	physical	17277779	NA	BioGRID
TRAF4	Affinity Capture-Western	physical	23973329	NA	BioGRID
TRAF5	Affinity Capture-Western	physical	17384642	NA	BioGRID
TRAF6	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, coimmunoprecipitation	association, physical, physical association	10094049, 10882101, 10921914, 11259596, 11518704, 12242293, 12496252, 12609980, 14633987, 16517750, 16543409, 18758450, 19112497, 19232515, 19521662, 19675569, 19820695, 19843958, 21822258, 22643835, 22851693, 22924441, 24434549, 25963657, 26038599, 27249171, 27501752	0.35, 0.67	BioGRID, IntAct, MINT
TRAIP	Affinity Capture-Western	physical	27847407	NA	BioGRID
TRIM5	Affinity Capture-Western	physical	21512573	NA	BioGRID
TRIM8	Affinity Capture-Western, Biochemical Activity	physical	22084099, 27956576, 27981609	NA	BioGRID
UBC	Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down	physical, physical association	16845370, 19820695, 28190767	0.66	BioGRID, IntAct, MINT
USP18	Affinity Capture-Western	physical	23825189, 26240016, 28718215	NA	BioGRID
USP2	Affinity Capture-Western	physical	23264041	NA	BioGRID
USP4	Affinity Capture-Western, Biochemical Activity	physical	21331078	NA	BioGRID
VRK2	Affinity Capture-Western, pull down	association, physical, physical association	17709393, 18286207	0.35, 0.40	BioGRID, IntAct
WDR34	Affinity Capture-Western, Two-hybrid	physical	19521662	NA	BioGRID
XIAP	Affinity Capture-Western, Reconstituted Complex	physical	11865055, 12048196, 19584092	NA	BioGRID
XPO1	Affinity Capture-MS	physical	26673895	NA	BioGRID
YEATS2	Affinity Capture-MS, Affinity Capture-Western	physical	18838386	NA	BioGRID
YWHAE	Affinity Capture-MS, Affinity Capture-Western	physical	20462248	NA	BioGRID
ZNF593	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT
ZNF746	Two-hybrid, two hybrid	physical, physical association	21900206	0.37	BioGRID, IntAct, MINT