Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
SMAD1	6767	COSM4605884,	upper_aerodigestive_tract	carcinoma	p.E26K	Substitution - Missense	4:145514689-145514689,	PATHOGENIC	0.98754	25056374