Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ACVRL1 Biochemical Activity physical 19592636 NA BioGRID AKR1B1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT ANKRD27 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT AP2A2 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT APC two hybrid array physical association 24412244 0.37 IntAct, MINT APP Reconstituted Complex physical 21832049 NA BioGRID AR Affinity Capture-Western, Co-localization, PCA, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence microscopy, protein complementation assay colocalization, physical, physical association 17183365, 23734213 0.60 BioGRID, IntAct, MINT AXIN2 two hybrid array physical association 24412244 0.37 IntAct, MINT BMP7 Phenotypic Suppression genetic 11438941 NA BioGRID BMPR1A Biochemical Activity, two hybrid array physical, physical association 24412244, 9136927 0.37 BioGRID, IntAct, MINT BUB1 two hybrid array physical association 24412244 0.37 IntAct, MINT CAMSAP1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT CCNC protein kinase assay phosphorylation reaction 19914168 0.44 IntAct CCND1 two hybrid array physical association 24412244 0.37 IntAct, MINT CCNT1 protein kinase assay phosphorylation reaction 19914168 0.44 IntAct CDK7 Biochemical Activity physical 19914168 NA BioGRID CDK8 Affinity Capture-Western, Biochemical Activity, anti tag coimmunoprecipitation physical, physical association 19914168 0.40 BioGRID, IntAct CDK9 Biochemical Activity physical 19914168 NA BioGRID CHMP3 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT CREBBP Affinity Capture-Western physical 10673036, 11239394 NA BioGRID CTDSP1 anti tag coimmunoprecipitation physical association 16882717 0.40 IntAct CTDSP2 anti tag coimmunoprecipitation physical association 16882717 0.40 IntAct CTDSPL anti tag coimmunoprecipitation physical association 16882717 0.40 IntAct CTNNA1 two hybrid array physical association 24412244 0.37 IntAct, MINT DDX5 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down association, physical association 18548003 0.61 IntAct DLC1 two hybrid array physical association 24412244 0.37 IntAct, MINT DNMT3L Reconstituted Complex physical 24952347 NA BioGRID DROSHA anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down association, physical association 18548003 0.56 IntAct DVL1 Reconstituted Complex physical 12650946 NA BioGRID EP300 Affinity Capture-Western physical 10205054, 10673036, 16613856, 20851880, 22365546 NA BioGRID ERBB2 two hybrid array physical association 24412244 0.37 IntAct, MINT ERBIN Reconstituted Complex physical 12650946 NA BioGRID FBXW7 two hybrid array physical association 24412244 0.37 IntAct, MINT FOXG1 Reconstituted Complex physical 11387330 NA BioGRID FOXO3 Affinity Capture-Western physical 17289590 NA BioGRID FRZB Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT GLI3 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct GMEB1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT GSK3B Biochemical Activity, Co-localization, protein kinase assay, proximity ligation assay phosphorylation reaction, physical, physical association 18045539, 25241761 0.61 BioGRID, IntAct HBP1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT HDAC1 Affinity Capture-Western physical 14699069 NA BioGRID HGS Affinity Capture-Western physical 11094085 NA BioGRID HIPK2 Affinity Capture-Western, Reconstituted Complex physical 12874272 NA BioGRID HMGA2 Affinity Capture-Western physical 18425117 NA BioGRID HOXA5 Two-hybrid physical 20211142 NA BioGRID HOXC8 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 10224145 NA BioGRID ICK Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT INPP4A Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT IRF2BP1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT KAT2A Affinity Capture-Western physical 15009097 NA BioGRID KDM6B Affinity Capture-Western physical 20667911 NA BioGRID KMT2B two hybrid physical association 15231748 0.37 IntAct, MINT KMT2D Two-hybrid physical 15231748 NA BioGRID LEF1 Affinity Capture-Western physical 15750622 NA BioGRID LEMD3 Two-hybrid, two hybrid, two hybrid array, two hybrid prey pooling approach physical, physical association 15231748, 15489854, 0.62 BioGRID, IntAct, MINT LMNA Two-hybrid physical 24623722 NA BioGRID MAPK1 Biochemical Activity physical 17289590, 18045539, 19914168 NA BioGRID MAST4 Two-hybrid physical 15231748 NA BioGRID MAST4 two hybrid physical association 15231748 0.37 IntAct, MINT MECOM Reconstituted Complex physical 15849193 NA BioGRID MED15 Affinity Capture-Western, coimmunoprecipitation physical, physical association 12167862 0.40 BioGRID, IntAct, MINT MED24 Affinity Capture-Western, coimmunoprecipitation physical, physical association 12167862 0.40 BioGRID, IntAct, MINT MED6 Affinity Capture-Western, coimmunoprecipitation physical, physical association 12167862 0.40 BioGRID, IntAct, MINT MEN1 Affinity Capture-Western physical 12649288 NA BioGRID MGA Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT MKL2 two hybrid physical association 15231748 0.37 IntAct, MINT MLH1 two hybrid array physical association 24412244 0.37 IntAct, MINT MLH3 two hybrid array physical association 24412244 0.37 IntAct, MINT MRTFB Two-hybrid physical 15231748 NA BioGRID MSH2 two hybrid array physical association 24412244 0.37 IntAct, MINT MUTYH two hybrid array physical association 24412244 0.37 IntAct, MINT NEDD4 Affinity Capture-Western, Two-hybrid, two hybrid physical, physical association 15231748, 21308777 0.37 BioGRID, IntAct, MINT NEDD9 Affinity Capture-Western, Two-hybrid, two hybrid physical, physical association 11118211, 15231748 0.37 BioGRID, IntAct, MINT NEUROG1 Phenotypic Enhancement, Phenotypic Suppression, Reconstituted Complex genetic, physical 11239394 NA BioGRID NKX3-2 Affinity Capture-Western, Reconstituted Complex physical 14612411 NA BioGRID NOTCH2 Two-hybrid physical 15231748 NA BioGRID NOTCH2 two hybrid physical association 15231748 0.37 IntAct, MINT NRAS two hybrid array physical association 24412244 0.37 IntAct, MINT NUP214 Affinity Capture-Western physical 17289590 NA BioGRID OAZ1 Two-hybrid physical 11571290 NA BioGRID OAZ3 Two-hybrid physical 11438941 NA BioGRID PARD3 Reconstituted Complex physical 12650946 NA BioGRID PAX6 Affinity Capture-Western physical 17251190 NA BioGRID PDGFRL two hybrid array physical association 24412244 0.37 IntAct, MINT PIAS1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT PIAS4 Affinity Capture-Western, Two-hybrid, two hybrid physical, physical association 12904571, 15231748 0.37 BioGRID, IntAct, MINT PIGQ Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT PPM1A Affinity Capture-Western physical 22588298 NA BioGRID PSMB4 Affinity Capture-Western, Two-hybrid, two hybrid physical, physical association 11438941, 11571290, 12097147, 15231748 0.37 BioGRID, IntAct, MINT PSMD1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT PSMD11 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT PTPN12 two hybrid array physical association 24412244 0.37 IntAct, MINT PUM1 Two-hybrid physical 15231748 NA BioGRID PUM1 two hybrid physical association 15231748 0.37 IntAct, MINT RFX1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT RUNX1 Affinity Capture-Western physical 10531362 NA BioGRID RUNX2 Affinity Capture-Western, Co-localization physical 10531362, 10962029, 17215250, 20851880 NA BioGRID RUNX3 Affinity Capture-Western physical 10531362 NA BioGRID SF3B1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT SKI Affinity Capture-Western, Reconstituted Complex physical 12426322, 12874272, 14699069 NA BioGRID SKIL Affinity Capture-Western physical 12426322 NA BioGRID SMAD1 Two-hybrid, cosedimentation through density gradient, molecular sieving, two hybrid, x-ray crystallography direct interaction, physical, physical association 11779505, 15231748, 9111321 0.71 BioGRID, IntAct, MINT SMAD2 Affinity Capture-MS, Two-hybrid physical 18729074, 9111321 NA BioGRID SMAD3 Affinity Capture-MS, Two-hybrid physical 18729074, 9111321 NA BioGRID SMAD4 Affinity Capture-Luminescence, Affinity Capture-Western, Co-fractionation, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, cosedimentation through density gradient, molecular sieving, two hybrid, two hybrid array, two hybrid prey pooling approach association, direct interaction, physical, physical association 10531362, 11700304, 11779505, 12167862, 12874272, 14701756, 15231748, 15761153, 17183365, 21454478, 24412244, 26555259, 28468752, 9111321, 9436979, 0.91 BioGRID, IntAct, MINT SMAD5 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT SMAD6 Affinity Capture-Western, Two-hybrid, anti tag coimmunoprecipitation, two hybrid association, physical, physical association 11483516, 12857866, 9256479, 9436979 0.57 BioGRID, IntAct SMAD7 Affinity Capture-Western physical 26555259 NA BioGRID SMARCE1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT SMURF1 Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Protein-peptide, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, pull down, two hybrid direct interaction, physical, physical association 14701756, 15221015, 15231748, 16611643, 17289590, 17510966, 17676934, 19914168, 19917253, 21685363, 21708152, 22152476, 22670624, 24828823, 28881580 0.54, 0.57 BioGRID, IntAct, MINT SMURF2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, nuclear magnetic resonance, two hybrid, two hybrid array, two hybrid prey pooling approach direct interaction, physical, physical association 11016919, 11158580, 14701756, 15221015, 15231748, 20937913, 28468752, 28514442, 0.73 BioGRID, IntAct, MINT SNIP1 Two-hybrid physical 10887155 NA BioGRID SNRNP70 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT SOX5 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT SS18L1 Two-hybrid physical 20211142 NA BioGRID STARD13 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT STAT3 Affinity Capture-Western physical 10205054 NA BioGRID STUB1 Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Reconstituted Complex, Two-hybrid physical 14701756, 21454478, 23344957 NA BioGRID TCF20 Two-hybrid physical 20211142 NA BioGRID TGIF1 Affinity Capture-Western physical 10199400 NA BioGRID TLR2 two hybrid array physical association 24412244 0.37 IntAct, MINT TOB1 Affinity Capture-Western physical 11163184 NA BioGRID TP53 Affinity Capture-Western physical 22588298 NA BioGRID TTF1 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT TTF2 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT TUBA4A anti bait coimmunoprecipitation physical association 17183365 0.40 IntAct, MINT UBC Two-hybrid physical 11438941 NA BioGRID UCHL3 Affinity Capture-Western, anti tag coimmunoprecipitation physical, physical association 21453705 0.40 BioGRID, IntAct, MINT USP15 Affinity Capture-Western physical 21947082, 22344298 NA BioGRID USP9X Affinity Capture-Western physical 19135894 NA BioGRID WDR77 Affinity Capture-Western, Two-hybrid physical 23734213 NA BioGRID WWP1 Affinity Capture-Western physical 15221015, 15359284 NA BioGRID XPC Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT XPO1 Affinity Capture-MS physical 26673895 NA BioGRID YAP1 Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, anti tag coimmunoprecipitation, isothermal titration calorimetry direct interaction, physical, physical association 19914168, 21685363 0.54 BioGRID, IntAct YY1 Reconstituted Complex physical 12808092 NA BioGRID ZCCHC12 Affinity Capture-Western, Reconstituted Complex physical 18160706, 19416967 NA BioGRID ZDHHC3 Two-hybrid physical 15231748 NA BioGRID ZDHHC3 two hybrid physical association 15231748 0.37 IntAct, MINT ZEB1 Affinity Capture-Western physical 12743038 NA BioGRID ZEB2 Affinity Capture-Western, Two-hybrid, two hybrid physical, physical association 15231748, 22365546 0.37 BioGRID, IntAct, MINT ZNF251 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT ZNF423 Affinity Capture-Western physical 10660046, 14630787 NA BioGRID ZNF510 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT ZNF512B Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT ZNF521 Affinity Capture-Western physical 14630787 NA BioGRID ZNF76 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT ZSCAN4 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT