Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PHLPP2	29149	COSM3755044,	soft_tissue	haemangioblastoma	p.L1016S	Substitution - Missense	16:71649815-71649815,	PATHOGENIC	0.99568	25589003
PHLPP2	29149	COSM3755044,	soft_tissue	haemangioblastoma	p.L1016S	Substitution - Missense	16:71649815-71649815,	PATHOGENIC	0.99568	25589003
PHLPP2	29149	COSM3755044,	soft_tissue	haemangioblastoma	p.L1016S	Substitution - Missense	16:71649815-71649815,	PATHOGENIC	0.99568	25589003
PHLPP2	29149	COSM3755044,	soft_tissue	haemangioblastoma	p.L1016S	Substitution - Missense	16:71649815-71649815,	PATHOGENIC	0.99568	25589003
PHLPP2	29149	COSM3755044,	soft_tissue	haemangioblastoma	p.L1016S	Substitution - Missense	16:71649815-71649815,	PATHOGENIC	0.99568	25589003
PHLPP2	29149	COSM3755044,	soft_tissue	haemangioblastoma	p.L1016S	Substitution - Missense	16:71649815-71649815,	PATHOGENIC	0.99568	25589003
PHLPP2	29149	COSM3755044,	soft_tissue	haemangioblastoma	p.L1016S	Substitution - Missense	16:71649815-71649815,	PATHOGENIC	0.99568	25589003
PHLPP2	29149	COSM3755044,	soft_tissue	haemangioblastoma	p.L1016S	Substitution - Missense	16:71649815-71649815,	PATHOGENIC	0.99568	25589003
PHLPP2	29149	COSM5609822,	skin	malignant_melanoma	p.S244F	Substitution - Missense	16:71684480-71684480,	PATHOGENIC	0.99426	26343386
PHLPP2	29149	COSM5609819,	skin	malignant_melanoma	p.P103L	Substitution - Missense	16:71702708-71702708,	PATHOGENIC	0.98885	26343386
PHLPP2	29149	COSM4604783,	upper_aerodigestive_tract	carcinoma	p.E75*	Substitution - Nonsense	16:71714573-71714573,	PATHOGENIC	0.98163	25056374
PHLPP2	29149	COSM3755045,	soft_tissue	haemangioblastoma	p.L465L	Substitution - coding silent	16:71676525-71676525,	PATHOGENIC	0.97706	25589003
PHLPP2	29149	COSM3755045,	soft_tissue	haemangioblastoma	p.L465L	Substitution - coding silent	16:71676525-71676525,	PATHOGENIC	0.97706	25589003
PHLPP2	29149	COSM3755045,	soft_tissue	haemangioblastoma	p.L465L	Substitution - coding silent	16:71676525-71676525,	PATHOGENIC	0.97706	25589003
PHLPP2	29149	COSM3755045,	soft_tissue	haemangioblastoma	p.L465L	Substitution - coding silent	16:71676525-71676525,	PATHOGENIC	0.97706	25589003
PHLPP2	29149	COSM5019484,	soft_tissue	haemangioblastoma	p.L327L	Substitution - coding silent	16:71679445-71679445,	PATHOGENIC	0.94092	25589003
PHLPP2	29149	COSM5609817,	skin	malignant_melanoma	p.I728I	Substitution - coding silent	16:71658328-71658328,	PATHOGENIC	0.89403	26343386
PHLPP2	29149	COSM5609824,	skin	malignant_melanoma	p.V405V	Substitution - coding silent	16:71678808-71678808,	PATHOGENIC	0.86402	26343386
PHLPP2	29149	COSM5609826,	skin	malignant_melanoma	p.L827L	Substitution - coding silent	16:71655344-71655344,	PATHOGENIC	0.79437	26343386
PHLPP2	29149	COSM5609821,	skin	malignant_melanoma	p.T1108I	Substitution - Missense	16:71649539-71649539,	NEUTRAL	0.49079	26343386
PHLPP2	29149	COSM5020062,	soft_tissue	haemangioblastoma	p.L514L	Substitution - coding silent	16:71669361-71669361,	NEUTRAL	0.22594	25589003
PHLPP2	29149	COSM5609828,	skin	malignant_melanoma	p.P501P	Substitution - coding silent	16:71672291-71672291,	NEUTRAL	0.12414	26343386
PHLPP2	29149	COSM5021099,	soft_tissue	haemangioblastoma	p.Q190H	Substitution - Missense	16:71690558-71690558,	NEUTRAL	0.12318	25589003
PHLPP2	29149	COSM5020983,	soft_tissue	haemangioblastoma	p.P1316P	Substitution - coding silent	16:71648914-71648914,	NEUTRAL	0.02069	25589003
PHLPP2	29149	COSM5611349,	skin	malignant_melanoma	p.L214F	Substitution - Missense	16:71684571-71684572,	Info_not_available	Info_not_available	26343386
PHLPP2	29149	COSM39332,	central_nervous_system	glioma	p.S502I	Substitution - Missense	16:71672289-71672289,	Info_not_available	0.5341	18772396