Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PFKFB3	8874	COSM40459,	central_nervous_system	glioma	p.A78T	Substitution - Missense	10:6215250-6215250,	PATHOGENIC	0.97835	18772396
PFKFB3	8874	COSM314096,	lung	carcinoma	p.K451R	Substitution - Missense	10:6226202-6226202,	PATHOGENIC	0.76982	22941188
PFKFB3	8874	COSM5027177,	breast	carcinoma	p.V17V	Substitution - coding silent	10:6203311-6203311,	NEUTRAL	0.04161	22722193