Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases AKT1 Reconstituted Complex, proximity ligation assay physical, physical association 14749719, 23397142, 24886428 0.40 BioGRID, IntAct APP Reconstituted Complex physical 21832049 NA BioGRID ARHGEF2 Affinity Capture-MS, Reconstituted Complex physical 14970201 NA BioGRID ARHGEF6 Affinity Capture-MS, Two-hybrid, tandem affinity purification, two hybrid association, physical, physical association 21900206, 23455922, 28514442 0.55 BioGRID, IntAct, MINT ARHGEF7 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, anti bait coimmunoprecipitation, classical fluorescence spectroscopy, nuclear magnetic resonance, pull down, tandem affinity purification, two hybrid pooling approach association, direct interaction, physical, physical association 11157752, 16101281, 16407834, 16492808, 16628223, 20936779, 23455922, 28514442 0.89 BioGRID, IntAct, MINT ARPC1B Affinity Capture-Western, Reconstituted Complex physical 14749719 NA BioGRID BAD Biochemical Activity physical 10611223, 15784622, 15849194, 19667065 NA BioGRID BAIAP2 Reconstituted Complex physical 11130076 NA BioGRID BMX Affinity Capture-Western, Reconstituted Complex physical 11382770 NA BioGRID BRSK1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex physical 22669945 NA BioGRID CDC42 Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, imaging technique, pull down, tandem affinity purification, two hybrid, two hybrid pooling approach association, direct interaction, physical, physical association 10360579, 10684602, 10802735, 11157984, 12606577, 12650940, 12879077, 15548653, 16678097, 18057010, 19596003, 20936779, 21029865, 21167153, 23455922, 24276241, 25150978, 7744004, 8107774, 9535855, 0.55, 0.94 BioGRID, IntAct, MINT CDK11A Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 12624090 NA BioGRID CDK5 Affinity Capture-Western, Biochemical Activity physical 11604394 NA BioGRID CHORDC1 Two-hybrid physical 19910486 NA BioGRID CPLANE1 Two-hybrid physical 20936779 NA BioGRID CRIPAK Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, confocal microscopy, protein kinase assay, pull down, two hybrid colocalization, phosphorylation reaction, physical, physical association 16278681 0.64 BioGRID, IntAct DYNLL1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, two hybrid physical, physical association 15193260, 17389360, 21988832 0.37 BioGRID, IntAct DYNLL2 Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct DYRK1B Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct EGFR PCA, Two-hybrid, ubiquitin reconstruction physical, physical association 24658140, 25402006 0.37 BioGRID, IntAct ELF3 Biochemical Activity, Reconstituted Complex physical 17491012 NA BioGRID ERBB2 Affinity Capture-Western physical 9774445 NA BioGRID ESR1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex physical 12374744, 16452229 NA BioGRID FBXO28 Affinity Capture-MS, tandem affinity purification association, physical 23455922, 28514442 0.35 BioGRID, IntAct FGB Affinity Capture-MS physical 28514442 NA BioGRID FSD1 Affinity Capture-MS physical 28514442 NA BioGRID GIT1 Affinity Capture-MS, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification association, physical, physical association 16628223, 23455922, 25852190 0.67 BioGRID, IntAct, MINT GIT2 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 16628223, 25852190 0.40 BioGRID, IntAct, MINT GNB1 Affinity Capture-Western physical 12887923 NA BioGRID H2AFX Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25852190 0.35 BioGRID, IntAct HGS Reconstituted Complex physical 11397816 NA BioGRID HIST1H3A Biochemical Activity, Reconstituted Complex physical 12151336 NA BioGRID HIST1H4A Biochemical Activity physical 15864311 NA BioGRID HSP90AA1 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct ICAM1 Affinity Capture-MS physical 28514442 NA BioGRID ILKAP Co-fractionation physical 26344197 NA BioGRID LIMK1 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, fluorescence microscopy, protein kinase assay, pull down colocalization, phosphorylation reaction, physical, physical association 10559936 0.62 BioGRID, IntAct LPXN Affinity Capture-MS physical 28514442 NA BioGRID LYN Affinity Capture-Luminescence physical 23503679 NA BioGRID MAP3K1 Biochemical Activity physical 12228228 NA BioGRID MAPK14 Affinity Capture-Western physical 18586681 NA BioGRID MYLK Biochemical Activity physical 10092231 NA BioGRID MYNN Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct MYO6 Biochemical Activity physical 9852149 NA BioGRID NCK1 Affinity Capture-Western, Reconstituted Complex, pull down physical, physical association 10026169, 10372803, 11157752, 11557983, 15784622, 8824201, 9851874 0.40 BioGRID, IntAct, MINT NCK2 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, tandem affinity purification, two hybrid array, two hybrid prey pooling approach, validated two hybrid association, physical, physical association 10026169, 11557983, 23455922, 25416956, 26186194, 28514442, 0.77 BioGRID, IntAct OR2K2 Affinity Capture-MS physical 28514442 NA BioGRID PAK1 Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Co-fractionation physical 10975528, 11804587, 16278681, 18586681 NA BioGRID PAK1IP1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 11371639 NA BioGRID PAK2 Affinity Capture-MS, tandem affinity purification association, physical 23455922 0.35 BioGRID, IntAct PKLR Affinity Capture-Western physical 12006652 NA BioGRID PLCG1 Reconstituted Complex physical 12085993 NA BioGRID PPAT Co-fractionation physical 26344197 NA BioGRID PPM1A Biochemical Activity physical 18586681 NA BioGRID PPP1CA Biochemical Activity physical 18586681 NA BioGRID PPP2CA Biochemical Activity physical 18586681 NA BioGRID PYCARD Affinity Capture-Western, anti tag coimmunoprecipitation physical, physical association 25402006 0.40 BioGRID, IntAct RAC1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, fluorescent resonance energy transfer, pull down, two hybrid, two hybrid pooling approach association, direct interaction, physical, physical association 11030651, 11130076, 11950930, 12650940, 12879077, 15075243, 15143066, 15212766, 15548653, 15673687, 15688026, 16002993, 16492808, 16551621, 16678097, 17245428, 17389360, 19270716, 19277120, 19327867, 19596003, 19693014, 19732720, 19961560, 20810653, 20936779, 21029865, 21167153, 21454543, 21474670, 22117219, 22581261, 24172987, 24625804, 24792722, 25150978, 25468898, 25819133, 25843002, 26175416, 9535855 0.37, 0.64, 0.98 BioGRID, IntAct, MINT RAF1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, protein kinase assay phosphorylation reaction, physical 11733498, 17097642 0.44 BioGRID, IntAct, MINT RELA Affinity Capture-Western physical 26036343 NA BioGRID RHOJ Affinity Capture-MS, Two-hybrid, pull down physical, physical association 10967094, 14521508, 28514442 0.40 BioGRID, IntAct RHOU Reconstituted Complex physical 26598620 NA BioGRID SETX Affinity Capture-MS physical 28514442 NA BioGRID SH3KBP1 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 16407834 0.40 BioGRID, IntAct, MINT SLC25A41 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID SNW1 Affinity Capture-MS, anti bait coimmunoprecipitation association, physical 20467437 0.35 BioGRID, IntAct, MINT SORBS3 Affinity Capture-Western, Reconstituted Complex physical 15784622 NA BioGRID SOX2 Affinity Capture-MS physical 28514442 NA BioGRID TAS2R41 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID TGFBR1 Affinity Capture-Western, Reconstituted Complex physical 15761153 NA BioGRID TGFBR2 Affinity Capture-Western, Reconstituted Complex physical 15761153 NA BioGRID TGM2 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT YWHAG Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct YWHAZ Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct ZBTB18 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct ZC3H7A Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct ZNF418 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct ZNF823 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct ZNF83 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct