Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
AK2 	anti tag coimmunoprecipitation	physical association	26496610	0.40	IntAct
AKT1	Biochemical Activity, anti tag coimmunoprecipitation, protein kinase assay	association, phosphorylation reaction, physical, physical association	17512525, 18292230, 19014373	0.44, 0.50	BioGRID, IntAct, MINT
APOE	Protein-peptide, Reconstituted Complex, electrophoretic mobility-based method	direct interaction, physical, physical association	7566652, 8620924	0.54	BioGRID, IntAct
APP	Protein-peptide, Reconstituted Complex, comigration in sds page, confocal microscopy, enzyme linked immunosorbent assay, peptide array, protein kinase assay, surface plasmon resonance	colocalization, direct interaction, phosphorylation reaction, physical	16446437	0.44, 0.62, 0.63	BioGRID, IntAct
BAG6 	anti tag coimmunoprecipitation	association	26496610	0.35	IntAct
BIN1	Co-crystal Structure, Reconstituted Complex, anti bait coimmunoprecipitation, confocal microscopy, pull down	colocalization, physical, physical association	23399914, 28755476	0.40, 0.56	BioGRID, IntAct
CDK5	Biochemical Activity, protein kinase assay	phosphorylation reaction, physical	12387894, 17078951, 19527721, 9353289, 9735171	0.44	BioGRID, IntAct, MINT
CKAP5	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
DCTN1	Affinity Capture-Western, Co-purification, Proximity Label-MS, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, fluorescence microscopy, proximity-dependent biotin identification, pull down, two hybrid	association, colocalization, direct interaction, physical, physical association	17932487, 26638075	0.35, 0.61	BioGRID, IntAct, MINT
EBI-4399559	anti tag coimmunoprecipitation	association, physical association	18292230, 25686248	0.64	IntAct
EGFR	PCA, Two-hybrid, ubiquitin reconstruction	physical, physical association	24658140, 25402006	0.37	BioGRID, IntAct
EZR	proximity-dependent biotin identification	association	29568061	0.35	IntAct
FKBP4	Affinity Capture-Western, far western blotting	direct interaction, physical	20133804	0.44	BioGRID, IntAct
FYN	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, pull down, surface plasmon resonance	direct interaction, physical, physical association	11826099, 16115884, 21692989	0.40, 0.44	BioGRID, IntAct, MINT
GAR1	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
GSK3A	Biochemical Activity, protein kinase assay	phosphorylation reaction, physical	16446437, 7931292, 9735171	0.44	BioGRID, IntAct
GSK3B	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti tag coimmunoprecipitation, protein kinase assay, pull down	direct interaction, phosphorylation reaction, physical, physical association	10090741, 12048243, 12387894, 14612456, 17078951, 17512525, 19014373, 19527721, 21985244, 22965877, 24165324, 9546672, 9771888	0.44, 0.74	BioGRID, IntAct, MINT
HSP90AB1	classical fluorescence spectroscopy, nuclear magnetic resonance, x ray scattering	direct interaction	24581495	0.62	IntAct
HTRA1	atomic force microscopy, cosedimentation in solution, fluorescence microscopy, isothermal titration calorimetry, protease assay, transmission electron microscopy	direct interaction, protein cleavage	26436840	0.67	IntAct
KATNA1 	anti tag coimmunoprecipitation	association	26496610	0.35	IntAct
LRRK2	Affinity Capture-Western, Biochemical Activity, anti tag coimmunoprecipitation, protein kinase assay, pull down	phosphorylation reaction, physical, physical association	22303461, 24113872	0.40, 0.44, 0.68	BioGRID, IntAct
MAPT	Reconstituted Complex, anti bait coimmunoprecipitation, atomic force microscopy, comigration in sds page, fluorescence microscopy, surface plasmon resonance, transmission electron microscopy	direct interaction, physical, physical association	16446437, 17535890, 26436840, 9353289	0.44, 0.71	BioGRID, IntAct
MARK1 	proximity ligation assay	physical association	23666762	0.40	IntAct
MARK2 	proximity ligation assay	physical association	23001711, 23666762	0.59	IntAct
MARK3	FRET, proximity ligation assay	physical, physical association	23666762	0.40	BioGRID, IntAct
MARK4	Biochemical Activity, FRET, proximity ligation assay	physical, physical association	14594945, 23666762	0.40	BioGRID, IntAct
P4HB	anti tag coimmunoprecipitation, confocal microscopy, isothermal titration calorimetry	colocalization, direct interaction, physical association	24098548	0.44, 0.46	IntAct
PASK	peptide array	phosphorylation reaction	21418524	0.44	IntAct, MINT
PIN1P1	nuclear magnetic resonance	direct interaction	16024016	0.44	IntAct, MINT
PRNP	anti bait coimmunoprecipitation	association, physical association	24028865	0.50	IntAct
RPS6KA1	Biochemical Activity, protein kinase assay	phosphorylation reaction, physical	17512525	0.44	BioGRID, IntAct, MINT
RPS6KA3	Biochemical Activity, protein kinase assay	phosphorylation reaction, physical	17512525	0.44	BioGRID, IntAct, MINT
RPS6KA5	Biochemical Activity, protein kinase assay	phosphorylation reaction, physical	17512525	0.44	BioGRID, IntAct, MINT
RPS6KB1	Biochemical Activity, anti bait coimmunoprecipitation, protein kinase assay	phosphorylation reaction, physical, physical association	16364302, 17512525	0.40, 0.44	BioGRID, IntAct, MINT
SCLT1	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
SGK1	Biochemical Activity, protein kinase assay	phosphorylation reaction, physical	15650334, 17512525	0.44	BioGRID, IntAct, MINT
SLC1A2	Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, pull down	association, physical	19527721	0.46	BioGRID, IntAct, MINT
SNCA	Affinity Capture-Western, Co-localization, Co-purification, Reconstituted Complex, pull down	direct interaction, physical, physical association	10464279, 15904919, 17408955, 21127069, 21985244	0.54	BioGRID, IntAct, MINT
SPICE1	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
SQSTM1	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	15953362, 25686248	0.40	BioGRID, IntAct
SRC	Biochemical Activity, surface plasmon resonance	direct interaction, physical	16115884	0.44	BioGRID, IntAct, MINT
STAU1	imaging technique, tandem affinity purification	association, colocalization	15121898	0.43	IntAct
STUB1 	anti tag coimmunoprecipitation, filter binding, pull down	association, physical association	16275660, 18292230	0.50, 0.52	IntAct
SYNCRIP	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
TFEB	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
TIGD6	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
TTLL6 	anti tag coimmunoprecipitation	physical association	24065130	0.40	IntAct, MINT
USP43	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
YWHAQ	Affinity Capture-Western, coimmunoprecipitation	association, physical	15650334	0.35	BioGRID, IntAct, MINT
YWHAZ	Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, biochemical, coimmunoprecipitation, comigration in non denaturing gel electrophoresis, cross-linking study, molecular sieving	association, direct interaction, physical, physical association	10840038, 15650334, 17317006, 19138662, 19647741	0.62, 0.72	BioGRID, IntAct, MINT