Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ABL1 Affinity Capture-Western, Biochemical Activity physical 16014719, 18070606 NA BioGRID AK2 Affinity Capture-MS physical 26496610 NA BioGRID AK2 anti tag coimmunoprecipitation physical association 26496610 0.40 IntAct AKT1 Biochemical Activity, anti tag coimmunoprecipitation, protein kinase assay association, phosphorylation reaction, physical, physical association 17512525, 18292230, 19014373 0.44, 0.50 BioGRID, IntAct, MINT APOE Protein-peptide, Reconstituted Complex, electrophoretic mobility-based method direct interaction, physical, physical association 7566652, 8620924 0.54 BioGRID, IntAct APP Protein-peptide, Reconstituted Complex, comigration in sds page, confocal microscopy, enzyme linked immunosorbent assay, peptide array, protein kinase assay, surface plasmon resonance colocalization, direct interaction, phosphorylation reaction, physical 16446437 0.44, 0.62, 0.63 BioGRID, IntAct ARMC1 Affinity Capture-MS physical 28514442 NA BioGRID BAG1 Affinity Capture-Western, Reconstituted Complex physical 17954934 NA BioGRID BAG6 Affinity Capture-MS physical 26496610 NA BioGRID BAG6 anti tag coimmunoprecipitation association 26496610 0.35 IntAct BIN1 Co-crystal Structure, Reconstituted Complex, anti bait coimmunoprecipitation, confocal microscopy, pull down colocalization, physical, physical association 23399914, 28755476 0.40, 0.56 BioGRID, IntAct CALM1 Reconstituted Complex physical 2123288 NA BioGRID CAMK2A Biochemical Activity physical 17512525 NA BioGRID CAPN2 Biochemical Activity physical 14993287 NA BioGRID CDCA8 Affinity Capture-MS physical 28514442 NA BioGRID CDK2 Biochemical Activity physical 19014373 NA BioGRID CDK5 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 12387894, 17078951, 19527721, 9353289, 9735171 0.44 BioGRID, IntAct, MINT CDK5R1 Biochemical Activity physical 19527721 NA BioGRID CKAP5 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct CSNK1A1 Biochemical Activity physical 19014373, 9771888 NA BioGRID CSNK1D Biochemical Activity physical 16618118, 17101137 NA BioGRID CSNK2A1 Biochemical Activity physical 15882073 NA BioGRID DCTN1 Affinity Capture-Western, Co-purification, Proximity Label-MS, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, fluorescence microscopy, proximity-dependent biotin identification, pull down, two hybrid association, colocalization, direct interaction, physical, physical association 17932487, 26638075 0.35, 0.61 BioGRID, IntAct, MINT DENR Affinity Capture-MS physical 28514442 NA BioGRID DGUOK Affinity Capture-MS physical 26186194, 28514442 NA BioGRID DNAAF2 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID EBI-4399559 anti tag coimmunoprecipitation association, physical association 18292230, 25686248 0.64 IntAct EGFR PCA, Two-hybrid, ubiquitin reconstruction physical, physical association 24658140, 25402006 0.37 BioGRID, IntAct EP300 Biochemical Activity physical 20869593 NA BioGRID EWSR1 Proximity Label-MS physical 24999758 NA BioGRID EZR proximity-dependent biotin identification association 29568061 0.35 IntAct FKBP4 Affinity Capture-Western, far western blotting direct interaction, physical 20133804 0.44 BioGRID, IntAct FYN Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, pull down, surface plasmon resonance direct interaction, physical, physical association 11826099, 16115884, 21692989 0.40, 0.44 BioGRID, IntAct, MINT GAR1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct GNPNAT1 Affinity Capture-MS physical 28514442 NA BioGRID GSK3A Biochemical Activity, protein kinase assay phosphorylation reaction, physical 16446437, 7931292, 9735171 0.44 BioGRID, IntAct GSK3B Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti tag coimmunoprecipitation, protein kinase assay, pull down direct interaction, phosphorylation reaction, physical, physical association 10090741, 12048243, 12387894, 14612456, 17078951, 17512525, 19014373, 19527721, 21985244, 22965877, 24165324, 9546672, 9771888 0.44, 0.74 BioGRID, IntAct, MINT HAX1 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID HDAC6 Affinity Capture-Western, Reconstituted Complex physical 18636984 NA BioGRID HNRNPL Affinity Capture-RNA physical 28611215 NA BioGRID HSP90AB1 classical fluorescence spectroscopy, nuclear magnetic resonance, x ray scattering direct interaction 24581495 0.62 IntAct HSPA1A Affinity Capture-Western, Reconstituted Complex physical 23271055, 23554879 NA BioGRID HSPA4 Affinity Capture-Western, Reconstituted Complex physical 14962978, 21985244, 23271055 NA BioGRID HSPA8 Affinity Capture-MS, Affinity Capture-Western physical 14612456, 17954934, 28514442 NA BioGRID HTRA1 atomic force microscopy, cosedimentation in solution, fluorescence microscopy, isothermal titration calorimetry, protease assay, transmission electron microscopy direct interaction, protein cleavage 26436840 0.67 IntAct KATNA1 Affinity Capture-MS physical 26496610 NA BioGRID KATNA1 anti tag coimmunoprecipitation association 26496610 0.35 IntAct LIMS1 Affinity Capture-Western physical 23554879 NA BioGRID LRRK2 Affinity Capture-Western, Biochemical Activity, anti tag coimmunoprecipitation, protein kinase assay, pull down phosphorylation reaction, physical, physical association 22303461, 24113872 0.40, 0.44, 0.68 BioGRID, IntAct MAPK11 Biochemical Activity physical 9199504 NA BioGRID MAPK13 Biochemical Activity physical 9199504 NA BioGRID MAPK8 Biochemical Activity physical 9199504 NA BioGRID MAPT Reconstituted Complex, anti bait coimmunoprecipitation, atomic force microscopy, comigration in sds page, fluorescence microscopy, surface plasmon resonance, transmission electron microscopy direct interaction, physical, physical association 16446437, 17535890, 26436840, 9353289 0.44, 0.71 BioGRID, IntAct MARCH7 Affinity Capture-Western, Biochemical Activity, Two-hybrid physical 24905733 NA BioGRID MARK1 Biochemical Activity, FRET physical 10090741, 23666762, 8631898 NA BioGRID MARK1 proximity ligation assay physical association 23666762 0.40 IntAct MARK2 Biochemical Activity, Co-crystal Structure physical 24251416 NA BioGRID MARK2 proximity ligation assay physical association 23001711, 23666762 0.59 IntAct MARK3 FRET, proximity ligation assay physical, physical association 23666762 0.40 BioGRID, IntAct MARK4 Biochemical Activity, FRET, proximity ligation assay physical, physical association 14594945, 23666762 0.40 BioGRID, IntAct NME2 Affinity Capture-MS physical 28514442 NA BioGRID NUB1 Affinity Capture-Western physical 22965877 NA BioGRID NUFIP1 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID OGT Biochemical Activity physical 16434389 NA BioGRID P4HB anti tag coimmunoprecipitation, confocal microscopy, isothermal titration calorimetry colocalization, direct interaction, physical association 24098548 0.44, 0.46 IntAct PASK peptide array phosphorylation reaction 21418524 0.44 IntAct, MINT PEG10 FRET physical 23666762 NA BioGRID PIK3R1 Affinity Capture-Western, Reconstituted Complex physical 19681044 NA BioGRID PIN1 Affinity Capture-Western, Reconstituted Complex physical 10391244, 16365047 NA BioGRID PIN1P1 nuclear magnetic resonance direct interaction 16024016 0.44 IntAct, MINT PKN1 Biochemical Activity physical 11104762 NA BioGRID PPP5C Biochemical Activity physical 12435421 NA BioGRID PRKACA Biochemical Activity physical 10090741, 12435421, 19014373, 21127069, 9546672, 9771888 NA BioGRID PRKAR1A Biochemical Activity physical 19014373 NA BioGRID PRKN Affinity Capture-Western physical 14962978, 18248624 NA BioGRID PRNP anti bait coimmunoprecipitation association, physical association 24028865 0.50 IntAct PSEN1 Co-fractionation physical 9689133 NA BioGRID PSMC2 Affinity Capture-Western physical 15953362 NA BioGRID PTK2B Biochemical Activity physical 17512525 NA BioGRID PTPA Biochemical Activity physical 12435421 NA BioGRID RPS6KA1 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 17512525 0.44 BioGRID, IntAct, MINT RPS6KA3 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 17512525 0.44 BioGRID, IntAct, MINT RPS6KA5 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 17512525 0.44 BioGRID, IntAct, MINT RPS6KB1 Biochemical Activity, anti bait coimmunoprecipitation, protein kinase assay phosphorylation reaction, physical, physical association 16364302, 17512525 0.40, 0.44 BioGRID, IntAct, MINT RRP7A Affinity Capture-MS physical 28514442 NA BioGRID S100B Reconstituted Complex physical 11264299, 2833519 NA BioGRID SCLT1 Proximity Label-MS, proximity-dependent biotin identification association, physical 26638075 0.35 BioGRID, IntAct SGK1 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 15650334, 17512525 0.44 BioGRID, IntAct, MINT SIRT1 Affinity Capture-Western, Reconstituted Complex physical 20869593 NA BioGRID SLC1A2 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, pull down association, physical 19527721 0.46 BioGRID, IntAct, MINT SMAD2 Affinity Capture-Western physical 24964035 NA BioGRID SNCA Affinity Capture-Western, Co-localization, Co-purification, Reconstituted Complex, pull down direct interaction, physical, physical association 10464279, 15904919, 17408955, 21127069, 21985244 0.54 BioGRID, IntAct, MINT SPICE1 Proximity Label-MS, proximity-dependent biotin identification association, physical 26638075 0.35 BioGRID, IntAct SQSTM1 Affinity Capture-Western, anti tag coimmunoprecipitation physical, physical association 15953362, 25686248 0.40 BioGRID, IntAct SRC Biochemical Activity, surface plasmon resonance direct interaction, physical 16115884 0.44 BioGRID, IntAct, MINT STAU1 imaging technique, tandem affinity purification association, colocalization 15121898 0.43 IntAct STUB1 Affinity Capture-Western, Biochemical Activity, Co-purification, Protein-peptide, Reconstituted Complex physical 14612456, 14962978, 15447663, 16275660, 17304350, 18292230, 20466727, 23237806, 23554879 NA BioGRID STUB1 anti tag coimmunoprecipitation, filter binding, pull down association, physical association 16275660, 18292230 0.50, 0.52 IntAct STXBP1 Affinity Capture-Western physical 12963086 NA BioGRID SYK Affinity Capture-Western, Biochemical Activity physical 18070606 NA BioGRID SYNCRIP Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct TFEB Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct TIGD6 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct TRAF6 Biochemical Activity physical 15953362 NA BioGRID TTLL6 anti tag coimmunoprecipitation physical association 24065130 0.40 IntAct, MINT TUBA1A Affinity Capture-Western physical 22565157 NA BioGRID TUBA1B Reconstituted Complex physical 24905733 NA BioGRID TUBA4A Co-crystal Structure, Reconstituted Complex physical 19681044, 24251416 NA BioGRID TUBB3 Co-crystal Structure, Reconstituted Complex physical 24251416, 24905733 NA BioGRID UBASH3B Affinity Capture-Western, Biochemical Activity physical 16364302 NA BioGRID UBC Affinity Capture-Western physical 1723470 NA BioGRID UBE2D2 Biochemical Activity physical 14612456 NA BioGRID UBE2W Co-crystal Structure physical 25436519 NA BioGRID USP43 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct YWHAB Affinity Capture-Western physical 10840038, 12176984 NA BioGRID YWHAQ Affinity Capture-Western, coimmunoprecipitation association, physical 15650334 0.35 BioGRID, IntAct, MINT YWHAZ Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, biochemical, coimmunoprecipitation, comigration in non denaturing gel electrophoresis, cross-linking study, molecular sieving association, direct interaction, physical, physical association 10840038, 15650334, 17317006, 19138662, 19647741 0.62, 0.72 BioGRID, IntAct, MINT