Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
JUN	6204	COSM4842396,	large_intestine	carcinoma	p.*332S	Nonstop extension	1:58782076-58782076,	PATHOGENIC	0.95351	28481359
JUN	6204	COSM6952014,	prostate	carcinoma	p.L53F	Substitution - Missense	1:58782914-58782914,	PATHOGENIC	0.93482	28481359
JUN	6204	COSM6953893,	breast	carcinoma	p.P92Q	Substitution - Missense	1:58782796-58782796,	PATHOGENIC	0.92366	28481359
JUN	6204	COSM681630,	urinary_tract	carcinoma	p.E112Q	Substitution - Missense	1:58782737-58782737,	PATHOGENIC	0.90932	28481359
JUN	6204	COSM6919827,	large_intestine	carcinoma	p.E120K	Substitution - Missense	1:58782713-58782713,	PATHOGENIC	0.90771	28481359
JUN	6204	COSM681631,	breast	carcinoma	p.E112K	Substitution - Missense	1:58782737-58782737,	PATHOGENIC	0.9017	22722193
JUN	6204	COSM6974272,	lung	carcinoma	p.A117T	Substitution - Missense	1:58782722-58782722,	PATHOGENIC	0.89449	28481359
JUN	6204	COSM6912680,	breast	carcinoma	p.Q230*	Substitution - Nonsense	1:58782383-58782383,	PATHOGENIC	0.87147	28481359
JUN	6204	COSM6912680,	large_intestine	carcinoma	p.Q230*	Substitution - Nonsense	1:58782383-58782383,	PATHOGENIC	0.87147	28481359
JUN	6204	COSM6948784,	skin	malignant_melanoma	p.P100L	Substitution - Missense	1:58782772-58782772,	PATHOGENIC	0.86628	28481359
JUN	6204	COSM6961823,	pancreas	carcinoid-endocrine_tumour	p.Q321*	Substitution - Nonsense	1:58782110-58782110,	PATHOGENIC	0.85817	28481359
JUN	6204	COSM6920930,	ovary	carcinoma	p.D12H	Substitution - Missense	1:58783037-58783037,	PATHOGENIC	0.85193	28481359
JUN	6204	COSM4930069,	central_nervous_system	glioma	p.P244L	Substitution - Missense	1:58782340-58782340,	PATHOGENIC	0.8513	28481359
JUN	6204	COSM6926667,	lung	carcinoma	p.E293K	Substitution - Missense	1:58782194-58782194,	PATHOGENIC	0.84893	28481359
JUN	6204	COSM6919378,	soft_tissue	leiomyosarcoma	p.P240Q	Substitution - Missense	1:58782352-58782352,	PATHOGENIC	0.83933	28481359
JUN	6204	COSM6967156,	skin	carcinoma	p.M260I	Substitution - Missense	1:58782291-58782291,	PATHOGENIC	0.8262	28481359
JUN	6204	COSM6976745,	central_nervous_system	glioma	p.A255T	Substitution - Missense	1:58782308-58782308,	PATHOGENIC	0.82307	28481359
JUN	6204	COSM6045225,	large_intestine	carcinoma	p.N262S	Substitution - Missense	1:58782286-58782286,	PATHOGENIC	0.82076	28481359
JUN	6204	COSM6045225,	large_intestine	carcinoma	p.N262S	Substitution - Missense	1:58782286-58782286,	PATHOGENIC	0.82076	28481359
JUN	6204	COSM6952091,	large_intestine	carcinoma	p.M38I	Substitution - Missense	1:58782957-58782957,	PATHOGENIC	0.80738	28481359
JUN	6204	COSM6975752,	skin	carcinoma	p.T239I	Substitution - Missense	1:58782355-58782355,	PATHOGENIC	0.80105	28481359
JUN	6204	COSM6348397,	kidney	carcinoma	p.A72E	Substitution - Missense	1:58782856-58782856,	PATHOGENIC	0.79582	28481359
JUN	6204	COSM6971164,	lung	carcinoma	p.N15D	Substitution - Missense	1:58783028-58783028,	PATHOGENIC	0.78454	28481359
JUN	6204	COSM6975136,	lung	carcinoma	p.E75*	Substitution - Nonsense	1:58782848-58782848,	PATHOGENIC	0.78264	28481359
JUN	6204	COSM6689758,	large_intestine	carcinoma	p.E77*	Substitution - Nonsense	1:58782842-58782842,	PATHOGENIC	0.78075	28481359
JUN	6204	COSM6948474,	lung	carcinoma	p.L49M	Substitution - Missense	1:58782926-58782926,	PATHOGENIC	0.77808	28481359
JUN	6204	COSM6974835,	large_intestine	carcinoma	p.R78H	Substitution - Missense	1:58782838-58782838,	PATHOGENIC	0.75729	28481359
JUN	6204	COSM6945900,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A151T	Substitution - Missense	1:58782620-58782620,	PATHOGENIC	0.72903	28481359
JUN	6204	COSM6986183,	urinary_tract	carcinoma	p.S17*	Substitution - Nonsense	1:58783021-58783021,	NEUTRAL	0.47595	28481359
JUN	6204	COSM6968423,	kidney	carcinoma	p.Q204H	Substitution - Missense	1:58782459-58782459,	NEUTRAL	0.44219	28481359
JUN	6204	COSM5609214,	skin	malignant_melanoma	p.G185S	Substitution - Missense	1:58782518-58782518,	NEUTRAL	0.36278	26343386
JUN	6204	COSM6957871,	large_intestine	carcinoma	p.S29N	Substitution - Missense	1:58782985-58782985,	NEUTRAL	0.2558	28481359
JUN	6204	COSM6689759,	breast	carcinoma	p.P207Q	Substitution - Missense	1:58782451-58782451,	NEUTRAL	0.23639	28481359
JUN	6204	COSM5611314,	skin	malignant_melanoma	p.L53F	Substitution - Missense	1:58782914-58782915,	Info_not_available	Info_not_available	26343386
JUN	6204	COSM3751326,	soft_tissue	haemangioblastoma	p.Q250Q	Substitution - coding silent	1:58782321-58782321,	Info_not_available	0.55487	25589003
JUN	6204	COSM4693930, COSM5025290, COSM5847083, COSM6689752, COSM6907105, COSM6910573, COSM6913564, COSM6914751, COSM6915074, COSM6921794, COSM6922136, COSM6922187, COSM6929911, COSM6930792, COSM6934758, COSM6936436, COSM6943474, COSM6944858, COSM6952017, COSM6952089, COSM6952090, COSM6954914, COSM6956401, COSM6959982, COSM6964104, COSM6973813, COSM6975351, COSM6975603, COSM6980773, COSM6980912, COSM6983057,	biliary_tract, breast, large_intestine, lung, prostate, salivary_gland, skin, stomach	carcinoma, malignant_melanoma	p.A140fs*8, p.D105fs*2, p.E281fs*29, p.E293fs*16, p.G194C, p.H52fs*30, p.I253fs*9, p.K101fs*3, p.K101fs*6, p.K311fs*6, p.K56N, p.L98M, p.M142fs*8, p.M323fs*2, p.M38_A43delMTLNLA, p.N172Y, p.N299fs*11, p.P128H, p.P31L, p.Q304fs*5, p.Q36H, p.R116G, p.R263L, p.R270*, p.R54fs*27, p.S37fs*2, p.S37fs*69, p.T7_T8insMET, p.T91delT, p.T95fs*9, p.V284fs*1	Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Insertion - In frame, Substitution - Missense, Substitution - Nonsense	1:58782102-58782102, 1:58782140-58782141, 1:58782158-58782159, 1:58782174-58782175, 1:58782191-58782192, 1:58782222-58782222, 1:58782231-58782232, 1:58782263-58782264, 1:58782282-58782283, 1:58782313-58782314, 1:58782491-58782491, 1:58782557-58782557, 1:58782648-58782649, 1:58782653-58782653, 1:58782688-58782688, 1:58782725-58782725, 1:58782758-58782759, 1:58782770-58782771, 1:58782771-58782771, 1:58782779-58782779, 1:58782789-58782789, 1:58782799-58782801, 1:58782903-58782903, 1:58782911-58782912, 1:58782917-58782918, 1:58782942-58782959, 1:58782960-58782960, 1:58782961-58782962, 1:58782963-58782963, 1:58782978-58782979, 1:58783048-58783049,	Info_not_available	0.50071, .52269, .58869, .60399, .64724, .66098, .69662, Info_not_available	28481359