Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ACP1 Co-localization physical 12438242 NA BioGRID ACTB Affinity Capture-Western physical 22720799 NA BioGRID ACTN4 Co-localization physical 25241761 NA BioGRID ACTN4 anti bait coimmunoprecipitation, confocal microscopy, proximity ligation assay, two hybrid association, colocalization, physical association 16204054, 25241761 0.70 IntAct AHCTF1 display technology physical association 20195357 0.40 IntAct AHR Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 19651607, 23174221 0.40 BioGRID, IntAct AJAP1 Affinity Capture-Western physical 14595118 NA BioGRID AKAP12 display technology physical association 20195357 0.40 IntAct AKT1 Biochemical Activity physical 15492215, 17287208 NA BioGRID AMER1 Affinity Capture-MS, Reconstituted Complex, anti tag coimmunoprecipitation, pull down, tandem affinity purification association, direct interaction, physical, physical association 17510365, 26496610 0.71 BioGRID, IntAct AMOT Proximity Label-MS, proximity-dependent biotin identification colocalization, physical 24255178 0.35 BioGRID, IntAct ANP32A display technology physical association 20195357 0.40 IntAct AP2M1 Affinity Capture-MS, tandem affinity purification association, physical 24189400 0.35 BioGRID, IntAct AP3D1 display technology physical association 20195357 0.40 IntAct APC Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Co-localization, Far Western, Protein-peptide, Reconstituted Complex physical 10545404, 11251183, 11533658, 11707392, 11712088, 11972058, 12628243, 15327769, 15355978, 15525529, 16510874, 19576224, 21664290, 23840886, 25241761, 26496610, 27902311, 29045831, 8259519, 9286858 NA BioGRID APC anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, proximity ligation assay, pull down, tandem affinity purification, x-ray crystallography association, direct interaction, physical association 15327768, 15327769, 16212417, 17318191, 17510365, 22056988, 22682247, 25241761, 26496610, 8638126, 9707618 0.95 IntAct, MINT APC2 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 10074433, 16510875, 23840886, 9823329 NA BioGRID APP Reconstituted Complex physical 21832049 NA BioGRID APPL1 display technology physical association 20195357 0.40 IntAct AR Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, confocal microscopy, pull down, two hybrid association, colocalization, direct interaction, physical, physical association 10987273, 11792709, 11916967, 12588987, 12799378, 12944908, 14593076, 15060161, 15256534, 21741601, 21885566, 22187462 0.89 BioGRID, IntAct, MINT ARHGAP21 tandem affinity purification association 17510365 0.35 IntAct ARID4B display technology physical association 20195357 0.40 IntAct ARMC8 Affinity Capture-Western physical 18215130 NA BioGRID ASH2L Reconstituted Complex physical 16510874, 16510875 NA BioGRID ATF2 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 22304920 0.35 BioGRID, IntAct AURKA Affinity Capture-MS physical 26496610 NA BioGRID AXIN1 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification association, physical, physical association 10228155, 12421363, 12805222, 16199882, 16890161, 17318191, 17510365, 18593713, 18632848, 19131971, 19166851, 20128690, 20531388, 21242974, 22509369, 22682247, 22773187, 23892894, 23959799, 24976009, 26496610, 27902311, 29045831, 9734785 0.40, 0.94 BioGRID, IntAct, MINT AXIN2 Affinity Capture-Western, anti tag coimmunoprecipitation, tandem affinity purification association, physical, physical association 10966653, 17510365, 22056988 0.56 BioGRID, IntAct BCCIP display technology physical association 20195357 0.40 IntAct BCL3 Affinity Capture-Western physical 15829968 NA BioGRID BCL6 Reconstituted Complex, pull down physical, physical association 25402006 0.40 BioGRID, IntAct BCL9 Affinity Capture-Western, pull down, two hybrid physical, physical association 11955446, 24360964 0.51 BioGRID, IntAct BCL9L Affinity Capture-Western physical 24360964 NA BioGRID BOC Affinity Capture-Western physical 12634428 NA BioGRID BRCA1 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex physical 20215423, 26831064 NA BioGRID BRIX1 display technology physical association 20195357 0.40 IntAct BTF3 Affinity Capture-MS physical 15492215 NA BioGRID BTRC Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, PCA, Protein-peptide, Proximity Label-MS, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, enzymatic study, x-ray crystallography association, physical, physical association, ubiquitination reaction 10023660, 10074433, 10228155, 12820959, 14516475, 14706645, 16376880, 16798748, 17053147, 18354482, 18650423, 18805092, 18851830, 19053519, 19061640, 19150432, 19956254, 19966869, 20531388, 20851351, 21466614, 21829575, 22017875, 22682247, 22730322, 22912335, 23514615, 24451375, 24464578, 24469040, 24501426, 24561623, 24912152, 25149538, 25515538, 25873176, 25900982, 26091241, 26506240, 27001857, 27316454, 28018973, 9990852 0.93 BioGRID, IntAct, MINT CA9 Affinity Capture-Western physical 14567991 NA BioGRID CACYBP Affinity Capture-Western, Co-localization, proximity ligation assay physical, physical association 11389839, 21466614, 25241761 0.40 BioGRID, IntAct CALCOCO1 Phenotypic Enhancement genetic 16931570 NA BioGRID CARM1 Reconstituted Complex physical 11983685 NA BioGRID CASP3 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct CAV1 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 18356165, 19244345 0.40 BioGRID, IntAct CBL Affinity Capture-Western, Biochemical Activity physical 23744067, 25784557 NA BioGRID CBY1 Affinity Capture-Western, Reconstituted Complex, pull down direct interaction, physical 12712206, 18334222, 20096688 0.44 BioGRID, IntAct CCDC8 Affinity Capture-MS physical 24711643 NA BioGRID CCNA1 Affinity Capture-Western physical 14985333 NA BioGRID CCNA2 Affinity Capture-Western, Reconstituted Complex physical 14985333 NA BioGRID CCNE1 Affinity Capture-Western, Reconstituted Complex physical 14985333 NA BioGRID CDC27 Reconstituted Complex physical 16510875 NA BioGRID CDC73 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, pull down, two hybrid association, physical, physical association 16630820, 21726809 0.62 BioGRID, IntAct CDH1 Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Co-localization, FRET, Proximity Label-MS, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence microscopy, proximity ligation assay, pull down, surface plasmon resonance association, colocalization, physical, physical association 10381631, 10772923, 11113628, 11245482, 11254878, 11348595, 11401320, 11712088, 11960376, 12061792, 12169098, 12640114, 12830000, 15023525, 16125672, 16212417, 16574648, 16983094, 17220478, 17909039, 18593713, 18593907, 19016843, 22056988, 22158051, 22375065, 22715382, 22752307, 22850631, 23180380, 24424122, 24798214, 25344754, 25468996, 7542250, 7876318, 7954478, 8227214, 9233779, 9405455, 9535896, 9819408 0.95 BioGRID, IntAct, MINT CDH10 Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation association, physical 10861224, 26496610 0.35 BioGRID, IntAct CDH11 Affinity Capture-Western physical 10029089 NA BioGRID CDH18 Affinity Capture-Western physical 10207020 NA BioGRID CDH2 Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, tandem affinity purification association, physical, physical association 11835406, 12077367, 12604612, 14625392, 17057644, 17098867, 17510365, 17679699, 18948590, 21357690, 25143387 0.89 BioGRID, IntAct, MINT CDH3 Affinity Capture-Western, Co-purification physical 10381631, 10910767, 23180380 NA BioGRID CDH5 Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, competition binding, imaging technique, pull down association, colocalization, direct interaction, physical, physical association 12003790, 17057644, 18287330, 18662404, 20123964, 20224040, 22720799, 23243000, 28514442, 9434630 0.81 BioGRID, IntAct, MINT CDH6 Affinity Capture-Western physical 10207020 NA BioGRID CDH7 Affinity Capture-Western physical 10861224 NA BioGRID CDH8 Affinity Capture-MS, Affinity Capture-Western physical 28514442, 9521872 NA BioGRID CDH9 Affinity Capture-Western physical 10861224 NA BioGRID CDK2 Affinity Capture-Western, Reconstituted Complex physical 14985333 NA BioGRID CDK5R1 Affinity Capture-Western, Reconstituted Complex physical 11168528 NA BioGRID CDK6 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct CDON Affinity Capture-Western physical 12634428 NA BioGRID CEP128 Proximity Label-MS, proximity-dependent biotin identification association, physical 26638075 0.35 BioGRID, IntAct CFAP298 Affinity Capture-MS physical 26472760 NA BioGRID CFTR Affinity Capture-MS physical 26618866 NA BioGRID CHD8 Affinity Capture-Western, Reconstituted Complex physical 18378692, 22083958 NA BioGRID CHUK Affinity Capture-Western, Biochemical Activity, Reconstituted Complex physical 11527961, 12589056 NA BioGRID CITED1 Affinity Capture-Western physical 15843474 NA BioGRID CKAP5 tandem affinity purification association 17510365 0.35 IntAct CLTA display technology physical association 20195357 0.40 IntAct COPS3 Affinity Capture-Western physical 19576224 NA BioGRID COPS5 Affinity Capture-Western physical 19576224, 24882689 NA BioGRID COPS8 Affinity Capture-Western physical 19576224 NA BioGRID CREB1 Affinity Capture-Western physical 17962194 NA BioGRID CREBBP Affinity Capture-Western, Phenotypic Enhancement, anti bait coimmunoprecipitation, two hybrid genetic, physical, physical association 15782138, 16476742, 18347063, 21751375, 23273993, 26657156, 28648376 0.57 BioGRID, IntAct CRYAB Affinity Capture-Western, Protein-peptide, anti bait coimmunoprecipitation, pull down physical, physical association 17487982, 22158051 0.52 BioGRID, IntAct CSNK1A1 tandem affinity purification association 17510365 0.35 IntAct CSNK1E protein kinase assay phosphorylation reaction 11425858 0.44 IntAct CTBP1 Affinity Capture-Western physical 15525529, 24469828 NA BioGRID CTNNA1 Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical, physical association 12640114, 15492215, 17072306, 17098867, 19941816, 24509793, 26344197, 26496610, 7706414, 7954478, 9512503, 9762469 0.76 BioGRID, IntAct, MINT CTNNA2 Co-fractionation, anti tag coimmunoprecipitation physical, physical association 17679699, 26344197 0.40 BioGRID, IntAct CTNNA3 Affinity Capture-MS, Affinity Capture-Western, Co-localization physical 11590244, 23718855, 25241761, 28514442 NA BioGRID CTNNA3 proximity ligation assay physical association 25241761 0.40 IntAct CTNNBIP1 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, competition binding, pull down, tandem affinity purification, x-ray crystallography association, direct interaction, physical, physical association 10898789, 12408824, 12408825, 15893313, 17072306, 17353931, 17510365, 18287330, 21885566, 26912724, 28514442 0.92 BioGRID, IntAct, MINT CTNND1 Affinity Capture-Western physical 11712088, 9535896 NA BioGRID CUL1 Affinity Capture-Western, enzymatic study physical, ubiquitination reaction 10713156, 18805092 0.44 BioGRID, IntAct CUL3 Affinity Capture-MS physical 21145461 NA BioGRID CUL4A Affinity Capture-Western physical 17954973 NA BioGRID DACT1 anti bait coimmunoprecipitation, confocal microscopy association, colocalization, physical association 22470507 0.54 IntAct DAZAP2 Affinity Capture-Western physical 19304756 NA BioGRID DDB1 Affinity Capture-Western, anti bait coimmunoprecipitation association, physical 19651607 0.35 BioGRID, IntAct DDX1 Affinity Capture-MS physical 16230076 NA BioGRID DDX5 Affinity Capture-MS, Affinity Capture-Western physical 16230076 NA BioGRID DHX9 Affinity Capture-MS physical 16230076 NA BioGRID DKK1 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct DLG5 Affinity Capture-Western physical 12657639 NA BioGRID DLGAP1 Affinity Capture-Western physical 9286858 NA BioGRID DNAJC8 display technology physical association 20195357 0.40 IntAct DNMT1 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, confocal microscopy association, colocalization, physical association 25753001 0.63 IntAct DOT1L anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical association 20203130, 21103407 0.56 IntAct DSC3 Affinity Capture-Western physical 10769211 NA BioGRID DVL1 Affinity Capture-Western, Co-localization, proximity ligation assay physical, physical association 10806215, 25241761 0.40 BioGRID, IntAct DVL2 Affinity Capture-Western physical 10806215 NA BioGRID DVL3 Affinity Capture-Western physical 10806215 NA BioGRID E2F3 pull down association 22157815 0.35 IntAct, MINT EBI-10056674 electrophoretic mobility supershift assay physical association 22022540 0.40 IntAct EBI-10056677 electrophoretic mobility supershift assay physical association 22022540 0.40 IntAct EBI-1058500 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct EBI-4399559 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical association 24561623 0.58 IntAct EGFR Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, tandem affinity purification association, physical 11950845, 24189400, 9233779, 9535896 0.35 BioGRID, IntAct EGR1 Affinity Capture-Western, anti bait coimmunoprecipitation association, physical, physical association 21743491 0.50 BioGRID, IntAct ELAVL1 Reconstituted Complex physical 22544606 NA BioGRID EMD Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, filter binding physical, physical association 16858403 0.59 BioGRID, IntAct, MINT ENSG00000065361 chromatin immunoprecipitation assay association 21741601 0.35 IntAct ENSG00000089685 chromatin immunoprecipitation assay association 23245941 0.35 IntAct ENSG00000110092 chromatin immunoprecipitation assay association 18772112 0.35 IntAct ENSG00000117560 chromatin immunoprecipitation assay association 22022540 0.35 IntAct ENSG00000135245 chromatin immunoprecipitation assay association 15930302 0.35 IntAct ENSG00000136997 chromatin immunoprecipitation assay association 18772112 0.35 IntAct ENSG00000138795 chromatin immunoprecipitation assay association 22014570 0.35 IntAct ENSG00000160182 chromatin immunoprecipitation assay association 15304487 0.35 IntAct ENSG00000168646 chromatin immunoprecipitation assay association 15304487, 22014570 0.53 IntAct ENSG00000171552 chromatin immunoprecipitation assay association 23245941 0.35 IntAct ENSG00000177426 chromatin immunoprecipitation assay association 25873176 0.35 IntAct EP300 Affinity Capture-Luminescence, Affinity Capture-Western, Biochemical Activity, Phenotypic Enhancement, Reconstituted Complex genetic, physical 11050151, 12408825, 12861022, 15060161, 15572674, 15806138, 16990252, 26657156 NA BioGRID EP400 Affinity Capture-MS physical 16510874, 16510875 NA BioGRID EPAS1 Affinity Capture-MS physical 23275444 NA BioGRID EPHA2 anti bait coimmunoprecipitation physical association 18948590 0.40 IntAct ERBB2 Affinity Capture-Western, Co-localization, Far Western, Reconstituted Complex physical 11245482, 11950845, 7702605 NA BioGRID ERBIN Protein-peptide physical 15123239 NA BioGRID ERBIN fluorescence microscopy colocalization 12047349 0.27 IntAct, MINT ERMN display technology physical association 20195357 0.40 IntAct ESR1 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 15304487 0.40 BioGRID, IntAct ESR2 affinity chromatography technology association 21182203 0.35 IntAct ETS1 anti bait coimmunoprecipitation association 24562386 0.35 IntAct, MINT EZH2 Affinity Capture-Western, Reconstituted Complex physical 17502350, 19661437 NA BioGRID EZR Affinity Capture-Western physical 10462524 NA BioGRID FAF1 Affinity Capture-Western physical 21411632, 22730322, 26456834 NA BioGRID FANCA Affinity Capture-Western physical 22653977, 24469828 NA BioGRID FANCC Affinity Capture-Western, Co-localization physical 22653977, 24469828 NA BioGRID FANCE Affinity Capture-Western physical 24469828 NA BioGRID FANCF Affinity Capture-Western physical 24469828 NA BioGRID FANCG Affinity Capture-Western physical 22653977 NA BioGRID FAS Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct FBXO45 Affinity Capture-MS, Affinity Capture-Western physical 25143387 NA BioGRID FBXW11 Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification association, physical, physical association 10321728, 16085715, 17510365, 22017875, 22682247, 24500709, 25332235, 25515538, 25609649, 25900982 0.72 BioGRID, IntAct, MINT FBXW7 Affinity Capture-Western physical 27485116 NA BioGRID FER Biochemical Activity physical 12640114 NA BioGRID FERMT2 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence microscopy, pull down association, colocalization, direct interaction, physical association 22699938 0.68 IntAct, MINT FGFR1 Co-localization, anti bait coimmunoprecipitation, proximity ligation assay physical, physical association 11401320, 25241761 0.59 BioGRID, IntAct FHIT Affinity Capture-Western, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down direct interaction, physical, physical association 18077326 0.60 BioGRID, IntAct FHL2 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 12466281 NA BioGRID FLT1 proximity ligation assay physical association 23397142 0.40 IntAct FOXB1 Affinity Capture-MS, tandem affinity purification association, physical 25609649 0.35 BioGRID, IntAct, MINT FOXM1 Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, chromatin immunoprecipitation assay, confocal microscopy, pull down association, colocalization, direct interaction, physical, physical association 22014570, 26912724 0.40, 0.67 BioGRID, IntAct FOXO3 Affinity Capture-Western physical 15905404 NA BioGRID FOXO3 anti bait coimmunoprecipitation physical association 29361949 0.40 IntAct FOXO4 Affinity Capture-Western physical 15905404, 20874444 NA BioGRID FRMD5 fluorescence microscopy colocalization 22846708 0.27 IntAct, MINT FUS Affinity Capture-MS, Affinity Capture-Western, Two-hybrid physical 16230076 NA BioGRID FYN Biochemical Activity, Co-localization, proximity ligation assay physical, physical association 12640114, 25241761 0.40 BioGRID, IntAct GEMIN5 Affinity Capture-MS physical 16230076 NA BioGRID GLIS2 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, pull down, two hybrid pooling approach physical, physical association 17289029 0.58 BioGRID, IntAct, MINT GRIP1 Phenotypic Enhancement genetic 16990252 NA BioGRID GSK3A Affinity Capture-MS, Biochemical Activity, tandem affinity purification association, physical 17510365, 25897075, 26496610 0.35 BioGRID, IntAct GSK3B Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-localization, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, protein kinase assay, proximity ligation assay, proximity-dependent biotin identification, tandem affinity purification association, phosphorylation reaction, physical, physical association 10074433, 10228155, 10330181, 11251183, 11835406, 16039586, 17318191, 17510365, 19061640, 19107203, 19303846, 19576224, 21743491, 22699938, 23602568, 24451375, 25241761, 25897075, 26359353, 27902311, 29045831, 29568061, 8638126 0.94 BioGRID, IntAct, MINT HDAC1 Affinity Capture-Western, anti tag coimmunoprecipitation physical, physical association 10958684, 16204248, 17412698, 19166851 0.40 BioGRID, IntAct, MINT HDAC4 Affinity Capture-Western physical 16204248 NA BioGRID HDAC6 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 18356165 0.40 BioGRID, IntAct HDAC7 Affinity Capture-MS, Affinity Capture-Western, Co-localization physical 20224040, 21836063 NA BioGRID HERC2 Affinity Capture-MS physical 25476789 NA BioGRID HERC5 Affinity Capture-Western physical 20581239, 28744352 NA BioGRID HIC1 anti tag coimmunoprecipitation, imaging technique colocalization, physical association 16724116 0.46 IntAct, MINT HIF1A Affinity Capture-Western physical 24650032 NA BioGRID HIF1A anti bait coimmunoprecipitation physical association 24650032 0.40 IntAct HINT1 Affinity Capture-Western, Two-hybrid physical 16014379, 22647378 NA BioGRID HIST1H1C Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex physical 18258596 NA BioGRID HNF4A Affinity Capture-Western, Co-localization, Reconstituted Complex, proximity ligation assay physical, physical association 12944908, 25241761 0.40 BioGRID, IntAct HNRNPA1 Affinity Capture-MS, Affinity Capture-Western physical 15492215, 16230076 NA BioGRID HNRNPA2B1 Affinity Capture-MS, Affinity Capture-Western physical 16230076 NA BioGRID HNRNPK Affinity Capture-Western physical 16230076 NA BioGRID HNRNPM Affinity Capture-MS physical 16230076 NA BioGRID HSP90AB1 Affinity Capture-MS physical 15492215 NA BioGRID HSPA1B Affinity Capture-MS physical 15492215 NA BioGRID HSPA8 Affinity Capture-MS physical 15492215 NA BioGRID HTT Affinity Capture-Western, two hybrid physical, physical association 17500595, 20531388 0.37 BioGRID, IntAct HUWE1 Affinity Capture-MS physical 25147182 NA BioGRID IFRD1 Affinity Capture-Western physical 16204248 NA BioGRID IGF1R anti bait coimmunoprecipitation association, physical association 22261717 0.50 IntAct, MINT IKBKB Affinity Capture-Western, Co-localization, Reconstituted Complex, proximity ligation assay physical, physical association 11527961, 25241761 0.40 BioGRID, IntAct ILK Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25852190 0.35 BioGRID, IntAct IQGAP1 Reconstituted Complex, anti bait coimmunoprecipitation, confocal microscopy colocalization, physical, physical association 11734550, 22662192 0.46 BioGRID, IntAct ISG15 Affinity Capture-Western physical 20581239 NA BioGRID JADE1 Affinity Capture-Western, Biochemical Activity physical 18806787 NA BioGRID JRK anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down association, physical association 21399610 0.58 IntAct, MINT JUP Affinity Capture-MS, Affinity Capture-Western, Co-localization, anti tag coimmunoprecipitation, proximity ligation assay, tandem affinity purification association, physical, physical association 11712088, 17510365, 25241761, 26496610, 9535896 0.67 BioGRID, IntAct KANK1 anti bait coimmunoprecipitation physical association 16968744 0.40 IntAct KAT2A Affinity Capture-Western, Reconstituted Complex physical 16510874, 20937768 NA BioGRID KAT2B Affinity Capture-Western, Biochemical Activity, Reconstituted Complex physical 18987336 NA BioGRID KCTD1 Affinity Capture-Western, Phenotypic Suppression, Reconstituted Complex genetic, physical 24736394 NA BioGRID KDM1A anti bait coimmunoprecipitation association 25753001 0.35 IntAct KIAA1109 display technology physical association 20195357 0.40 IntAct KLF5 Affinity Capture-Western physical 19435907 NA BioGRID KMT2A Affinity Capture-MS, Reconstituted Complex physical 16510874, 16510875 NA BioGRID KMT2D Reconstituted Complex physical 16510874, 16510875 NA BioGRID KSR2 anti tag coimmunoprecipitation association 27086506 0.35 IntAct L3MBTL3 display technology physical association 20195357 0.40 IntAct LAMP1 proximity-dependent biotin identification, pull down association 29568061 0.46 IntAct LATS2 Affinity Capture-Western, Proximity Label-MS, Reconstituted Complex physical 24255178, 24360964 NA BioGRID LDHB Affinity Capture-MS physical 15492215 NA BioGRID LEF1 Affinity Capture-Western, Co-localization, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, tandem affinity purification association, direct interaction, physical, physical association 10890911, 10958684, 11751639, 11835406, 12077367, 12748295, 15525529, 15684397, 15728254, 15768032, 16204248, 16510874, 16510875, 17510365, 17517646, 18077326, 18296023, 20123964, 21743491, 8757136, 9419974 0.86 BioGRID, IntAct LEO1 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 16630820 0.40 BioGRID, IntAct LGALS9 Affinity Capture-MS physical 17353931 NA BioGRID LINC01194 Affinity Capture-Western physical 14612521 NA BioGRID LMNA Affinity Capture-Western physical 15355978 NA BioGRID LMNB1 Affinity Capture-Western physical 26912724 NA BioGRID LRP2 display technology physical association 20195357 0.40 IntAct LRP6 Affinity Capture-Western, anti tag coimmunoprecipitation physical, physical association 16890161 0.40 BioGRID, IntAct MAGI1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 10772923 NA BioGRID MAGI2 Affinity Capture-Western physical 11526121 NA BioGRID MAP1LC3B anti bait coimmunoprecipitation, pull down direct interaction, physical association 23736261 0.60 IntAct, MINT MAP3K2 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex physical 26884171 NA BioGRID MAPK6 anti tag coimmunoprecipitation association 26972000 0.35 IntAct MAPK8 Affinity Capture-Western, Biochemical Activity physical 19667122 NA BioGRID MAPK9 Affinity Capture-Western, Biochemical Activity physical 19667122 NA BioGRID MAPRE1 Affinity Capture-MS physical 26496610 NA BioGRID MCM2 Affinity Capture-MS physical 25963833 NA BioGRID MCM7 anti bait coimmunoprecipitation association 23764002 0.35 IntAct MEN1 Affinity Capture-Western, Reconstituted Complex physical 16510874, 16510875, 19074834 NA BioGRID MET Affinity Capture-Western physical 11254878 NA BioGRID MLLT10 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down association, direct interaction, physical association 20203130, 21103407 0.66 IntAct MOV10 Affinity Capture-RNA physical 22658674 NA BioGRID MSN Co-fractionation physical 26344197 NA BioGRID MUC1 Affinity Capture-Western, Reconstituted Complex physical 11152665, 11483589, 11877440, 12618757, 12750561, 9139698, 9819408 NA BioGRID MYO7A Affinity Capture-Western physical 11080149 NA BioGRID NCOA2 anti bait coimmunoprecipitation physical association 12588987 0.40 IntAct, MINT NDRG1 Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation association, physical, physical association 17220478 0.50 BioGRID, IntAct NDRG2 cosedimentation colocalization 23068607 0.35 IntAct, MINT NEK2 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex physical 24501426 NA BioGRID NFKB1 Affinity Capture-Western, Co-localization, anti bait coimmunoprecipitation, proximity ligation assay, pull down direct interaction, physical, physical association 15829968, 19358846, 25241761 0.67 BioGRID, IntAct, MINT NLK Affinity Capture-Western physical 12556497 NA BioGRID NONO Affinity Capture-MS, Affinity Capture-Western physical 16230076 NA BioGRID NOS3 anti bait coimmunoprecipitation, proximity ligation assay physical association 25062958 0.52 IntAct NOTCH1 Affinity Capture-Western, Reconstituted Complex physical 19000719 NA BioGRID NR4A1 Affinity Capture-Western physical 21986938, 26359353 NA BioGRID NR5A1 Reconstituted Complex, Two-hybrid physical 12554773 NA BioGRID NR5A2 molecular sieving, pull down, x-ray crystallography direct interaction, physical association 22187462 0.65 IntAct NSD2 Affinity Capture-Western physical 22028615 NA BioGRID NTRK1 Affinity Capture-MS physical 25921289 NA BioGRID NUDT5 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct NUMB anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical association 24561623 0.40, 0.50 IntAct NUP153 Affinity Capture-Western physical 22110128 NA BioGRID NUP62 Affinity Capture-Western physical 22110128 NA BioGRID NUP98 Affinity Capture-Western physical 22110128 NA BioGRID NXF1 Affinity Capture-RNA physical 22658674 NA BioGRID OBSL1 Affinity Capture-MS physical 24711643 NA BioGRID PARD3 Co-localization physical 25241761 NA BioGRID PARD3 anti bait coimmunoprecipitation, proximity ligation assay physical association 17057644, 25241761 0.59 IntAct, MINT PARP1 Affinity Capture-MS physical 16230076 NA BioGRID PARP2 protein array adp ribosylation reaction 21812934 0.44 IntAct, MINT PBDC1 display technology physical association 20195357 0.40 IntAct PECAM1 Affinity Capture-Western, Co-localization, anti bait coimmunoprecipitation, proximity ligation assay association, physical, physical association 10801826, 25241761 0.56 BioGRID, IntAct PHB2 Affinity Capture-MS physical 17353931 NA BioGRID PHB2 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct PIK3R1 Co-localization, Reconstituted Complex, proximity ligation assay physical, physical association 10477752, 25241761 0.40 BioGRID, IntAct PIN1 Reconstituted Complex physical 11533658 NA BioGRID PITX2 Affinity Capture-Western, Co-localization, anti tag coimmunoprecipitation, proximity ligation assay association, physical, physical association 12464179, 19174163, 25241761 0.56 BioGRID, IntAct, MINT PKD1 Affinity Capture-Western physical 11113628 NA BioGRID PKM Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down physical, physical association 22056988, 27485204 0.52 BioGRID, IntAct PKP4 fluorescence microscopy colocalization 12047349 0.27 IntAct, MINT PLEKHA7 anti bait coimmunoprecipitation association 28877994 0.35 IntAct PLK1 Affinity Capture-MS, Affinity Capture-Western physical 21610149 NA BioGRID PML Affinity Capture-Western, Reconstituted Complex physical 12384561, 22155184 NA BioGRID POU5F1 Affinity Capture-Western physical 23539445 NA BioGRID PPARG Affinity Capture-Western physical 15665104, 19495794, 24735796 NA BioGRID PPM1A anti bait coimmunoprecipitation association 10644691 0.35 IntAct, MINT PRKCA Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 21949397, 21952047 0.40 BioGRID, IntAct, MINT PRKCG Biochemical Activity physical 25639486 NA BioGRID PRKN Affinity Capture-Western physical 25877876 NA BioGRID PROP1 Affinity Capture-Western, Reconstituted Complex physical 16678101 NA BioGRID PRPF38B display technology physical association 20195357 0.40 IntAct PRPF6 Affinity Capture-MS physical 16230076 NA BioGRID PSEN1 Affinity Capture-Western, Reconstituted Complex physical 10341227, 16126725, 16306047, 17360711, 9738936, 9852041 NA BioGRID PTBP3 anti bait coimmunoprecipitation association 22575643 0.35 IntAct, MINT PTEN Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 20123964, 20372837 0.40 BioGRID, IntAct PTGS2 Affinity Capture-RNA, Protein-RNA physical 22544606 NA BioGRID PTH1R fluorescence microscopy, proximity ligation assay, two hybrid colocalization, physical association 23124878 0.54 IntAct PTK7 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid physical association 21132015 0.58 IntAct, MINT PTN Affinity Capture-Western physical 10706604 NA BioGRID PTPN1 Reconstituted Complex physical 12377785 NA BioGRID PTPN11 Affinity Capture-Western physical 10681592 NA BioGRID PTPN12 phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPN13 Biochemical Activity physical 10951583 NA BioGRID PTPN14 Affinity Capture-MS, Affinity Capture-Western physical 12808048 NA BioGRID PTPRB phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRC phosphatase assay, pull down dephosphorylation reaction, physical association 12370829, 19167335 0.61 IntAct, MINT PTPRF Affinity Capture-Western, Reconstituted Complex physical 11245482, 9245795 NA BioGRID PTPRG phosphatase assay dephosphorylation reaction, physical association 19167335, 21112398 0.61 IntAct, MINT PTPRJ Affinity Capture-Western, phosphatase assay, pull down dephosphorylation reaction, physical, physical association 12370829, 19167335 0.61 BioGRID, IntAct, MINT PTPRK Affinity Capture-Western, Reconstituted Complex physical 8663237 NA BioGRID PTPRO phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRU Affinity Capture-Western physical 12501215, 16574648, 9054423 NA BioGRID PTPRZ1 Affinity Capture-Western physical 10706604 NA BioGRID PXN anti bait coimmunoprecipitation, pull down direct interaction, physical association 22728435 0.60 IntAct, MINT PYGO2 Affinity Capture-Western physical 24360964 NA BioGRID RAB8B Affinity Capture-Western physical 12639940 NA BioGRID RABAC1 cosedimentation colocalization 23068607 0.35 IntAct, MINT RANBP2 Affinity Capture-Western physical 22110128 NA BioGRID RB1CC1 Affinity Capture-Western, Two-hybrid physical 22751121 NA BioGRID RBBP5 Affinity Capture-Western, Reconstituted Complex physical 16510874, 16510875, 20937768 NA BioGRID RBM39 display technology physical association 20195357 0.40 IntAct RBMX Affinity Capture-MS physical 16230076 NA BioGRID RBX1 enzymatic study ubiquitination reaction 18805092 0.44 IntAct RELA anti bait coimmunoprecipitation physical association 23273993, 24072822 0.59 IntAct RNF14 Affinity Capture-Western, anti bait coimmunoprecipitation association, physical 23449499 0.35 BioGRID, IntAct, MINT RNF220 Affinity Capture-Western physical 25266658 NA BioGRID RNF4 Reconstituted Complex physical 27653698 NA BioGRID RPL21 display technology physical association 20195357 0.40 IntAct RPL41 display technology physical association 20195357 0.40 IntAct RPLP2 Affinity Capture-MS physical 15492215 NA BioGRID RPSA Affinity Capture-MS physical 15492215 NA BioGRID RUNX3 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, chromatin immunoprecipitation assay, pull down association, physical association 18772112 0.66 IntAct RUVBL1 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, anti tag coimmunoprecipitation association, physical, physical association 16510874, 16510875, 18087039, 9843967 0.50 BioGRID, IntAct RUVBL2 Affinity Capture-MS, Affinity Capture-Western, Co-localization, Reconstituted Complex physical 11080158, 15829968, 16699503, 20603076 NA BioGRID RXRA Affinity Capture-Western, Co-localization, proximity ligation assay physical, physical association 12771132, 25241761 0.40 BioGRID, IntAct RYK Affinity Capture-MS physical 21875946 NA BioGRID SAPCD1 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID SATB1 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, two hybrid direct interaction, physical, physical association 20126258 0.66 BioGRID, IntAct SCRIB fluorescence microscopy, phage display colocalization, physical association 24550280 0.46 IntAct, MINT SERBP1 Affinity Capture-MS physical 15492215 NA BioGRID SFN Affinity Capture-Western physical 26147002 NA BioGRID SH3KBP1 display technology physical association 20195357 0.40 IntAct SIAH1 Affinity Capture-Western, Biochemical Activity physical 20181957, 24882689, 27871173 NA BioGRID SIRT1 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 20439735 0.40 BioGRID, IntAct SKP1 Affinity Capture-Western, Co-localization, Protein-peptide, enzymatic study, proximity ligation assay, x-ray crystallography physical, physical association, ubiquitination reaction 11389839, 12820959, 18805092, 21466614, 25241761, 9990852 0.71 BioGRID, IntAct SLAMF7 Affinity Capture-MS physical 28514442 NA BioGRID SLC9A3R1 Affinity Capture-Western, Reconstituted Complex physical 12830000 NA BioGRID SLC9A3R2 Affinity Capture-MS, inference by socio-affinity scoring, tandem affinity purification association, physical, physical association 27173435, 0.51 BioGRID, IntAct SMAD2 Affinity Capture-Western physical 12000714, 20571128 NA BioGRID SMAD3 Affinity Capture-Western physical 12000714, 20571128, 21965288, 22241478 NA BioGRID SMAD4 Affinity Capture-Western physical 12000714 NA BioGRID SMAD7 Affinity Capture-Western, Co-localization physical 15684397, 18593713 NA BioGRID SMARCA4 Affinity Capture-Western, Two-hybrid, anti bait coimmunoprecipitation association, physical 11532957, 19571879 0.35 BioGRID, IntAct SMARCA5 Affinity Capture-MS, Reconstituted Complex physical 16510874, 16510875 NA BioGRID SMURF1 Affinity Capture-Western, Reconstituted Complex physical 26015066 NA BioGRID SNRPD1 Affinity Capture-MS physical 15492215 NA BioGRID SOX1 Affinity Capture-Western physical 22767186 NA BioGRID SOX17 anti bait coimmunoprecipitation association, physical association 17875931 0.50 IntAct SOX2 Affinity Capture-MS, Affinity Capture-Western physical 23539445, 23667531 NA BioGRID SOX6 Affinity Capture-Western, Co-localization, Reconstituted Complex physical 17412698 NA BioGRID SP1 Affinity Capture-Western physical 24798214 NA BioGRID SRC anti bait coimmunoprecipitation, protein kinase assay phosphorylation reaction, physical association 22056988 0.54 IntAct STK39 display technology physical association 20195357 0.40 IntAct STK4 tandem affinity purification association 23386615 0.35 IntAct STRN3 Proximity Label-MS, proximity-dependent biotin identification colocalization, physical 24255178 0.35 BioGRID, IntAct SUV39H1 Affinity Capture-Western physical 21726809 NA BioGRID TADA2A Affinity Capture-Western physical 18059173 NA BioGRID TADA3 Affinity Capture-Western physical 18059173 NA BioGRID TAX1BP3 Co-crystal Structure physical 18835279 NA BioGRID TBL1X Affinity Capture-Western, Co-localization, proximity ligation assay physical, physical association 11389839, 18193033, 25241761 0.40 BioGRID, IntAct TBL1XR1 Affinity Capture-Western physical 18193033 NA BioGRID TBX5 anti tag coimmunoprecipitation, chromatin immunoprecipitation assay association 23245941 0.46 IntAct TCF4 Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, pull down association, physical, physical association 11713476, 12657632, 12727872, 15060161, 15331612, 15525529, 15665104, 17072306, 17318191, 17412698, 17875931, 17909039, 17962194, 17983804, 18281465, 20126258, 21103407, 21743491, 22080605, 22699938, 23449499, 24532795, 24798214, 24876153, 25402006, 29361949 0.94 BioGRID, IntAct, MINT TCF7 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, tandem affinity purification association, direct interaction, physical association 16442529, 17510365, 19358846, 25678599 0.78 IntAct, MINT TCF7L1 Co-crystal Structure, Protein-peptide physical 11136974, 15327769 NA BioGRID TCF7L2 Affinity Capture-Western, Co-crystal Structure, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, x-ray crystallography association, direct interaction, physical, physical association 11713475, 11713476, 16230076, 16442529, 16569639, 16630820, 16724116, 17050667, 17283121, 17914096, 18772112, 19202075, 19304756, 19443654, 19816403, 20126258, 21670201, 22014570, 22056988, 22155184, 22304967, 26350900, 27902311 0.97 BioGRID, IntAct, MINT TERT anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical association 19571879 0.52 IntAct TES Affinity Capture-MS physical 28378594 NA BioGRID TFAP2A Affinity Capture-Western physical 15331612 NA BioGRID TGFBR2 Affinity Capture-Western physical 12000714 NA BioGRID TGIF1 fluorescence microscopy colocalization 25873176 0.27 IntAct TLE1 Reconstituted Complex physical 9751710 NA BioGRID TMPO anti bait coimmunoprecipitation physical association 16858403 0.40 IntAct, MINT TNIK anti bait coimmunoprecipitation, pull down association, direct interaction 19816403 0.52 IntAct, MINT TNRC6B display technology physical association 20195357 0.40 IntAct TOB1 Affinity Capture-Western physical 16890162 NA BioGRID TOP2A Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, fluorescence microscopy, two hybrid association, colocalization, physical, physical association 16230076, 17983804 0.57 BioGRID, IntAct TP53BP2 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical association 25344754 0.58 IntAct TRAF4 Affinity Capture-Western physical 24990246 NA BioGRID TRIB2 fluorescence microscopy colocalization 25311538 0.27 IntAct, MINT TRIM25 Affinity Capture-RNA physical 29117863 NA BioGRID TRIM33 Affinity Capture-Western, Biochemical Activity physical 25639486 NA BioGRID TRIM37 Affinity Capture-Western physical 26395261 NA BioGRID TRRAP Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex physical 16510874, 16510875, 18347063 NA BioGRID TUBA1A Affinity Capture-MS physical 15492215 NA BioGRID UBA1 enzymatic study ubiquitination reaction 18805092 0.44 IntAct UBE2B Affinity Capture-Western, Biochemical Activity, Reconstituted Complex physical 18339854, 22705350 NA BioGRID UBE2D1 Reconstituted Complex physical 18851830 NA BioGRID UBE2D2 enzymatic study ubiquitination reaction 18805092 0.44 IntAct UBE2R2 Biochemical Activity physical 27044868 NA BioGRID UBE3A Affinity Capture-Western, Biochemical Activity physical 27902311 NA BioGRID UBR5 Affinity Capture-Western, anti bait coimmunoprecipitation, confocal microscopy colocalization, physical, physical association 21118991, 28689657 0.46 BioGRID, IntAct UCHL1 Affinity Capture-Western physical 19536331 NA BioGRID UHRF2 Far Western, antibody array physical, physical association 21952639 0.40 BioGRID, IntAct UNK Affinity Capture-RNA physical 25737280 NA BioGRID USP15 Affinity Capture-Western physical 26884171 NA BioGRID USP4 Affinity Capture-Western physical 26189775 NA BioGRID USP7 Affinity Capture-Western, Biochemical Activity, Protein-peptide physical 29045831 NA BioGRID USP9X Affinity Capture-Western, Co-fractionation, Reconstituted Complex physical 10620020, 14742711, 27783990 NA BioGRID VCL Affinity Capture-Western physical 22720799, 9405455 NA BioGRID VEZT Affinity Capture-Western physical 11080149 NA BioGRID VHL anti bait coimmunoprecipitation physical association 16983094 0.40 IntAct WBP2 Affinity Capture-Western physical 27578003 NA BioGRID WWTR1 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical association 22234184, 23245942 0.64 IntAct, MINT XPO1 Affinity Capture-MS physical 26673895 NA BioGRID YAP1 Affinity Capture-MS, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, inference by socio-affinity scoring, pull down association, direct interaction, physical, physical association 21376238, 22234184, 23245941, 24976009, 27173435, 0.40, 0.88 BioGRID, IntAct, MINT YES1 anti bait coimmunoprecipitation association 23245941 0.35 IntAct YWHAZ Affinity Capture-MS, Affinity Capture-Western, coimmunoprecipitation association, physical 15492215, 17287208, 22912335 0.35 BioGRID, IntAct, MINT ZBTB33 Affinity Capture-Western, Reconstituted Complex physical 21670201 NA BioGRID ZFYVE9 Two-hybrid, two hybrid physical, physical association 15231748 0.37 BioGRID, IntAct, MINT ZIC3 Reconstituted Complex, pull down physical, physical association 25402006 0.40 BioGRID, IntAct ZMIZ1 Affinity Capture-MS physical 26522984 NA BioGRID