Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
ARHGDIA	Two-hybrid, two hybrid pooling approach	physical, physical association	16169070	0.37	BioGRID, IntAct
ARIH1 	anti tag coimmunoprecipitation	association	24076655	0.35	IntAct, MINT
AURKA	molecular sieving	physical association	24358021	0.40	IntAct
BANP	two hybrid array, two hybrid bait and prey pooling approach, validated two hybrid	physical association	25910212	0.56	IntAct
CCNA1	Affinity Capture-Western, Reconstituted Complex, two hybrid pooling approach	physical, physical association	15583032, 16774918, 18692475	0.37	BioGRID, IntAct, MINT
CCNA2 	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, footprinting, molecular sieving, nuclear magnetic resonance, surface plasmon resonance, x-ray crystallography	association, direct interaction, phosphorylation reaction, physical association	15890360, 16209941, 17254966, 20596027, 26496610, 8684460	0.94	IntAct
CCNB1	Affinity Capture-MS, anti tag coimmunoprecipitation, pull down	association, physical, physical association	26496610, 8756624	0.56	BioGRID, IntAct
CCNB2	molecular sieving	physical association	24358021	0.40	IntAct
CCND1	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation	association, physical, physical association	11360184, 11940657, 12036906, 15695403, 17053782, 17254966, 19556892, 19767775, 25416956, 26496610, 28514442, 8978686, 9106657, 9311993	0.69	BioGRID, IntAct
CCND2	Affinity Capture-MS, Two-hybrid, split luciferase complementation, two hybrid array, two hybrid bait and prey pooling approach, two hybrid pooling approach, validated two hybrid	physical, physical association	16189514, 25910212, 26186194, 28514442	0.70	BioGRID, IntAct
CCND3	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, two hybrid pooling approach	physical, physical association	10342870, 10597239, 11360184, 16189514, 16782892, 23718855, 26186194, 28514442, 8978686, 9716181	0.37	BioGRID, IntAct
CCNE1	Affinity Capture-Western, Biochemical Activity, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, proximity ligation assay, pull down	association, physical, physical association	10393546, 11940657, 12529437, 17254966, 17254967, 17293600, 19470470, 20837141, 25241761, 27175940, 8756624, 8891332, 8978686, 9192873, 9218599, 9311993, 9632134, 9660939, 9716181, 9891079	0.82	BioGRID, IntAct
CCNE2	Affinity Capture-Western, Two-hybrid, anti bait coimmunoprecipitation, molecular sieving, two hybrid	physical, physical association	24358021, 9840927, 9840943	0.65	BioGRID, IntAct
CDK1	Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, tandem affinity purification	association, physical	18615582, 23602568, 24358021, 26186194, 28514442	0.53	BioGRID, IntAct
CDK2	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-localization, Protein-peptide, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, footprinting, molecular sieving, proximity ligation assay, surface plasmon resonance, tandem affinity purification	association, direct interaction, physical, physical association	10198259, 10323868, 10393546, 10585280, 11940657, 12417722, 12529437, 12800980, 12972555, 15355997, 15557281, 15619620, 15647383, 15890360, 16326706, 16782892, 17053782, 17254966, 17254967, 17418410, 17671428, 18285702, 18615582, 18850315, 19631451, 21423803, 21439954, 23455922, 23602568, 24358021, 25241761, 25852190, 26186194, 26450989, 26496610, 27175940, 27998760, 28514442, 8978686, 9192873, 9218599, 9311993, 9380407, 9472014, 9632134, 9658399, 9660939, 9724724	0.97	BioGRID, IntAct, MINT
CDK3	Affinity Capture-MS, tandem affinity purification	association, physical	23602568, 26186194, 28514442	0.35	BioGRID, IntAct
CDK4	Affinity Capture-MS, Affinity Capture-Western, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, proximity ligation assay, tandem affinity purification	association, physical, physical association	10198259, 10908655, 11360184, 11940657, 15695403, 16326706, 16782892, 17053782, 18285702, 18615582, 18850315, 19470470, 20837141, 21439954, 23602568, 23707388, 25241761, 26186194, 28514442, 8978686, 9106657, 9311993, 9464540, 9632134, 9658399	0.87	BioGRID, IntAct, MINT
CDK5	Affinity Capture-MS, Biochemical Activity, Reconstituted Complex, anti tag coimmunoprecipitation, footprinting, surface plasmon resonance, tandem affinity purification	association, direct interaction, physical, physical association	15890360, 23455922, 23543736, 23602568, 25852190, 26186194, 28514442	0.84	BioGRID, IntAct
CDK5R1	surface plasmon resonance	physical association	15890360	0.40	IntAct
CDK6	Affinity Capture-MS, Affinity Capture-Western, Co-localization, proximity ligation assay	physical, physical association	11360184, 16782892, 18615582, 21439954, 25241761, 28514442	0.40	BioGRID, IntAct
CDKN1A	Co-localization, Phenotypic Enhancement, proximity ligation assay	genetic, physical, physical association	18850315, 25241761	0.40	BioGRID, IntAct
CHUK	protein kinase assay	phosphorylation reaction	23602409	0.44	IntAct
CKS1B	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Protein-peptide, Reconstituted Complex, enzymatic study, isothermal titration calorimetry, x-ray crystallography	physical, physical association, ubiquitination reaction	12140288, 12813041, 16209941, 18805092, 19584057, 23910095, 28514442	0.67	BioGRID, IntAct
COPS5	Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, fluorescence microscopy, pull down	association, colocalization, physical, physical association	12082530, 15480426, 16951171, 17951406, 18202760, 18285702, 22350412, 24671224, 28919423	0.60	BioGRID, IntAct
CUL1	Protein-peptide, Reconstituted Complex, enzymatic study, pull down	physical, physical association, ubiquitination reaction	10559916, 11961546, 18805092, 22959436	0.61	BioGRID, IntAct
EBI-4399559	anti bait coimmunoprecipitation	physical association	17050680	0.40	IntAct
GRB2	Co-fractionation, Reconstituted Complex, isothermal titration calorimetry	direct interaction, physical	11278754, 19523899	0.44	BioGRID, IntAct
IRF1	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
JAK2	Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation	physical, physical association	21423214	0.40	BioGRID, IntAct
KPNA2	pull down	association	20551905	0.35	IntAct, MINT
KPNA3	biochemical, pull down	association, physical association	15057270	0.58	IntAct
KPNA5	anti tag coimmunoprecipitation, biochemical, pull down	association, physical association	15057270, 22770219	0.72	IntAct
KPNA6	Reconstituted Complex, anti tag coimmunoprecipitation	physical, physical association	22770219	0.40	BioGRID, IntAct
LYN	Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation, protein kinase assay	phosphorylation reaction, physical, physical association	17254966	0.54	BioGRID, IntAct
MCM7	pull down, two hybrid fragment pooling approach	direct interaction, physical association	16289477	0.53	IntAct, MINT
NUTF2 	biochemical	physical association	15057270	0.40	IntAct
PIM1	anti bait coimmunoprecipitation	physical association	18593906	0.40	IntAct, MINT
RAN	biochemical	physical association	15057270	0.40	IntAct
RBX1	Biochemical Activity, enzymatic study	physical, ubiquitination reaction	18805092	0.44	BioGRID, IntAct
RHOA	Affinity Capture-Western, anti bait coimmunoprecipitation, pull down	direct interaction, physical, physical association	19470470, 23333463	0.54	BioGRID, IntAct
RPS6KA1	Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation, protein kinase assay	phosphorylation reaction, physical, physical association	19470470	0.54	BioGRID, IntAct
SCML2	anti bait coimmunoprecipitation	association, physical association	24358021	0.50	IntAct
SKP1	Protein-peptide, isothermal titration calorimetry, x-ray crystallography	physical, physical association	10559916, 16209941, 23910095	0.52	BioGRID, IntAct
SKP2	Affinity Capture-Western, Biochemical Activity, Protein-peptide, Reconstituted Complex, enzymatic study, isothermal titration calorimetry, pull down, x-ray crystallography	physical, physical association, ubiquitination reaction	10559916, 11463388, 11565034, 12042314, 12140288, 12813041, 15075339, 15355997, 15469821, 15735731, 16209941, 16774918, 18239684, 18805092, 19112177, 19686743, 20160477, 20160482, 20663873, 21237244, 21503567, 22310285, 22524983, 22632967, 22959436, 23910095, 23911321, 24085301, 26450989	0.75	BioGRID, IntAct
SRC	Affinity Capture-Western, Biochemical Activity, protein kinase assay	phosphorylation reaction, physical	17254967	0.44	BioGRID, IntAct
STMN1	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation	physical, physical association	15652749, 21423803	0.59	BioGRID, IntAct
THAP1	two hybrid array, two hybrid bait and prey pooling approach, validated two hybrid	physical association	25910212	0.56	IntAct
TRAF2	Co-localization, Two-hybrid, proximity ligation assay, two hybrid array, two hybrid bait and prey pooling approach, two hybrid pooling approach, validated two hybrid	physical, physical association	16189514, 25241761, 25910212	0.75	BioGRID, IntAct
UBA1	enzymatic study	ubiquitination reaction	18805092	0.44	IntAct
UBE2D2	Biochemical Activity, enzymatic study	physical, ubiquitination reaction	18805092, 19123975	0.44	BioGRID, IntAct
UCHL1	Affinity Capture-Western, anti bait coimmunoprecipitation, fluorescence microscopy	colocalization, physical, physical association	12082530	0.46	BioGRID, IntAct
YES1	protein kinase assay	phosphorylation reaction	17254967	0.44	IntAct
YWHAB	Reconstituted Complex, pull down	physical, physical association	15057270	0.40	BioGRID, IntAct
YWHAE	Affinity Capture-Western, Reconstituted Complex, pull down	physical, physical association	15057270	0.40	BioGRID, IntAct
YWHAG	pull down	physical association	15057270	0.40	IntAct
YWHAQ	Affinity Capture-Western, coimmunoprecipitation, experimental interaction detection	association, physical, physical association	12042314, 17470459, 18281517	0.72	BioGRID, IntAct, MINT