Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases BLNK Affinity Capture-MS, Affinity Capture-Western, pull down physical, physical association 18369315, 21482705, 21822214 0.40 BioGRID, IntAct, MINT CASP1 anti tag coimmunoprecipitation association 25605870 0.35 IntAct CBL Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, coimmunoprecipitation, experimental interaction detection, isothermal titration calorimetry, x-ray crystallography direct interaction, phosphorylation reaction, physical, physical association 10570266, 10617633, 11042121, 11331248, 11742985, 12435267, 15536084, 15556646, 15577829, 16289966, 18273061, 7721825, 8621719, 9857068 0.74 BioGRID, IntAct, MINT CD22 Affinity Capture-Western, coimmunoprecipitation association, physical, physical association 8627166, 8647200 0.62 BioGRID, IntAct CD37 anti bait coimmunoprecipitation association, physical association 22624718 0.50 IntAct CD3E Reconstituted Complex, pull down, surface plasmon resonance, x-ray crystallography association, physical 7761456, 9698567 0.60 BioGRID, IntAct, MINT CTTN Affinity Capture-Western, Co-localization, proximity ligation assay physical, physical association 25241761, 8636079 0.40 BioGRID, IntAct EGFR Protein-peptide, protein array direct interaction, physical 16273093 0.44 BioGRID, IntAct, MINT ERBB2 Protein-peptide, protein array direct interaction, physical 16273093 0.44 BioGRID, IntAct, MINT ERBB3 Protein-peptide, protein array direct interaction, physical 16273093 0.44 BioGRID, IntAct, MINT ERBB4 Protein-peptide, protein array direct interaction, physical 16273093 0.44 BioGRID, IntAct, MINT FAM46A luminescence based mammalian interactome mapping, two hybrid array, validated two hybrid physical association 25814554 0.57 IntAct FCER1G Reconstituted Complex, kinase scintillation proximity assay, pull down association, physical, physical association 8071371, 8810294, 9280292 0.56 BioGRID, IntAct, MINT FCGR1A Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct FCGR2A Affinity Capture-Western, Reconstituted Complex, pull down association, physical 11141335, 7487883, 9268059 0.35 BioGRID, IntAct, MINT FGR Affinity Capture-Western, Two-hybrid, two hybrid physical, physical association 11672534, 15536084 0.37 BioGRID, IntAct, MINT FLT3 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, confocal microscopy, protein kinase assay association, colocalization, phosphorylation reaction, physical association 24525236 0.64 IntAct GAB1 fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct HAVCR2 anti bait coimmunoprecipitation, pull down association 26492563 0.46 IntAct HCLS1 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct ITGB2 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 10961871, 12885943 0.40 BioGRID, IntAct KIT fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct LCK Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, pull down, two hybrid association, physical, physical association 15536084, 7539035, 8621719, 8798676 0.75 BioGRID, IntAct, MINT MAL anti bait coimmunoprecipitation association 22366891 0.35 IntAct MET fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct MSN pull down association 12387735 0.35 IntAct, MINT NLRP3 anti tag coimmunoprecipitation, protein kinase assay phosphorylation reaction, physical association 25605870 0.40, 0.44 IntAct PIK3R1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, pull down, two hybrid physical, physical association 15536084, 16921024 0.58 BioGRID, IntAct, MINT PIK3R2 Two-hybrid, two hybrid physical, physical association 15536084 0.37 BioGRID, IntAct, MINT PKM protein kinase assay phosphorylation reaction 24606918 0.44 IntAct PLCG1 Affinity Capture-Western, coimmunoprecipitation, pull down association, physical 7831290, 8657103 0.46 BioGRID, IntAct, MINT POU2AF1 fluorescence microscopy colocalization 16713566 0.27 IntAct PYCARD anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, protein kinase assay association, phosphorylation reaction, physical association 25605870 0.59 IntAct SH2D2A Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical, physical association 25416956 0.56 BioGRID, IntAct SH3BP2 Affinity Capture-Western, Two-hybrid, pull down association, physical 15345594, 20439986, 9846481 0.35 BioGRID, IntAct, MINT SIRPB1 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 10940905 0.40 BioGRID, IntAct STAT3 anti bait coimmunoprecipitation, two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical association 20133729, 21516116, 25416956, 0.82 IntAct, MINT SYK Biochemical Activity, Co-crystal Structure, protein kinase assay phosphorylation reaction, physical 16291755, 18070606, 25605870, 9698567 0.44 BioGRID, IntAct TERF1 Two-hybrid, bimolecular fluorescence complementation, pull down physical, physical association 21044950 0.51 BioGRID, IntAct TYROBP Reconstituted Complex, pull down physical, physical association 10940905, 9830044 0.40 BioGRID, IntAct UBASH3B Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, phosphatase assay, pull down dephosphorylation reaction, physical, physical association 20585042, 22267732 0.54 BioGRID, IntAct, MINT USP25 Affinity Capture-Western, Two-hybrid, two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical, physical association 19909739, 21516116, 25416956, 0.76 BioGRID, IntAct, MINT VAV2 Two-hybrid, pull down association, physical 11262396, 15345594 0.35 BioGRID, IntAct, MINT VCAM1 Affinity Capture-MS, cross-linking study association, physical 19738201, 22623428 0.35 BioGRID, IntAct