Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ARRB2 Affinity Capture-MS, Affinity Capture-Western, Co-localization, anti tag coimmunoprecipitation, proximity ligation assay association, physical, physical association 11226259, 15699045, 17620599, 25241761 0.56 BioGRID, IntAct BCL2 Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation, experimental interaction detection phosphorylation reaction, physical, physical association 15225643 0.49 BioGRID, IntAct, MINT BLVRA anti bait coimmunoprecipitation association, physical association 18463290 0.50 IntAct CASP8 Affinity Capture-Western, anti tag coimmunoprecipitation physical, physical association 17290218 0.40 BioGRID, IntAct, MINT CEP350 tandem affinity purification association 23602568 0.35 IntAct COPS6 Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation, protein kinase assay phosphorylation reaction, physical, physical association 26267535 0.54 BioGRID, IntAct CRKL proximity ligation assay physical association 23397142 0.40 IntAct CRP Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct CTSD Two-hybrid, two hybrid physical, physical association 18624398 0.37 BioGRID, IntAct DCC Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation association, physical 20434207 0.35 BioGRID, IntAct DUSP1 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Two-hybrid, protein kinase assay, pull down phosphorylation reaction, physical, physical association 10617468, 11278799, 16286470, 18519678, 27432908 0.54 BioGRID, IntAct DUSP3 Affinity Capture-Western, Biochemical Activity, phosphatase assay dephosphorylation reaction, physical 10224087, 12840032 0.44 BioGRID, IntAct, MINT DUSP4 Affinity Capture-MS, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach physical, physical association 16038800, 27432908, 27880917, 0.63 BioGRID, IntAct, MINT DUSP5 fluorescence microscopy, pull down, two hybrid colocalization, physical association 15713638 0.54 IntAct, MINT DUSP6 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation physical, physical association 12840032, 25515236, 26050649, 27432908, 27880917, 9535927, 9596579 0.40 BioGRID, IntAct, MINT DUSP7 phosphatase assay dephosphorylation reaction 9788880 0.44 IntAct, MINT DUSP9 Affinity Capture-MS, Reconstituted Complex, two hybrid physical, physical association 21908610, 27432908, 27880917, 9596579 0.37 BioGRID, IntAct, MINT EGLN3 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct ELK1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, protein kinase assay phosphorylation reaction, physical 10644696, 11279280, 11857080, 12220533, 12551925, 12594221, 12788955, 14557262, 15655247, 15782123, 15967991, 16291755, 20371703, 21655091, 8586671, 8846788, 9130707 0.44 BioGRID, IntAct ENAH Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct ETS1 Co-localization, anti bait coimmunoprecipitation, proximity ligation assay association, physical, physical association 22521293, 25241761 0.64 BioGRID, IntAct FGF5 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct GAPDH Two-hybrid, two hybrid physical, physical association 18624398 0.37 BioGRID, IntAct GNPTAB Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct HLA-B anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct HMGB1 Affinity Capture-MS, tandem affinity purification association, physical 23602568 0.35 BioGRID, IntAct HSCB anti bait coimmunoprecipitation association 28380382 0.35 IntAct ID2 Two-hybrid, two hybrid physical, physical association 18624398 0.37 BioGRID, IntAct IER3 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 12356731, 16456541 0.44 BioGRID, IntAct, MINT IFI35 Two-hybrid, two hybrid physical, physical association 18624398 0.37 BioGRID, IntAct JUN Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti bait coimmunoprecipitation association, physical 10419510, 11431474, 25609649 0.35 BioGRID, IntAct, MINT KSR1 anti tag coimmunoprecipitation association 27086506 0.35 IntAct KSR2 anti tag coimmunoprecipitation association 27086506 0.35 IntAct LCK Biochemical Activity, anti bait coimmunoprecipitation, pull down physical, physical association 15967991, 8626561 0.52 BioGRID, IntAct, MINT LYN anti bait coimmunoprecipitation association 22731636 0.35 IntAct MAP2K1 Affinity Capture-Western, Biochemical Activity, PCA, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, protein kinase assay phosphorylation reaction, physical, physical association 10757792, 11266467, 11279118, 11352917, 11823456, 12697810, 12788955, 17255949, 19058874, 21336309, 21675959, 23241949, 24623782 0.61 BioGRID, IntAct, MINT MAP3K3 protein kinase assay phosphorylation reaction 16407301 0.44 IntAct, MINT MAPK1 Affinity Capture-MS, Biochemical Activity, anti tag coimmunoprecipitation, protein kinase assay phosphorylation reaction, physical, physical association 16627622, 21110948, 23602568, 26267534 0.61 BioGRID, IntAct MAPK12 Affinity Capture-MS, tandem affinity purification association, physical 23602568 0.35 BioGRID, IntAct MAPK14 Affinity Capture-Western, PCA, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, proximity ligation assay physical, physical association 11157753, 12697810, 17255949, 18586681, 21675959, 22521293 0.66 BioGRID, IntAct, MINT MAPK3 Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, proximity ligation assay, tandem affinity purification association, physical, physical association 16424009, 19058874, 23397142, 23602568, 26344197 0.56 BioGRID, IntAct MAPKAPK5 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct MBP Affinity Capture-Western, Biochemical Activity, protein kinase assay phosphorylation reaction, physical 10371216, 10464310, 10958680, 10978313, 11258664, 11570821, 11983899, 12588875, 12944901, 14530346, 17255944, 17906618, 22778266, 8846788, 9596579 0.44 BioGRID, IntAct, MINT MKNK1 Reconstituted Complex, Two-hybrid, two hybrid array, two hybrid prey pooling approach physical, physical association 10922375, 9155017, 0.49 BioGRID, IntAct MTIF3 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct MTPN Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct NAV1 Affinity Capture-MS, tandem affinity purification association, physical 23602568 0.35 BioGRID, IntAct NOTCH1 Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, tandem affinity purification association, physical 23022380 0.46 BioGRID, IntAct, MINT OTUB1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26752685 0.35 BioGRID, IntAct PACSIN3 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct PARP1 protein kinase assay phosphorylation reaction 16627622 0.44 IntAct PDCD6IP Affinity Capture-MS, tandem affinity purification association, physical 23602568 0.35 BioGRID, IntAct PEA15 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach physical, physical association 11702783, 17255949, 0.63 BioGRID, IntAct, MINT PLEKHA7 anti bait coimmunoprecipitation association 28877994 0.35 IntAct PPID anti tag coimmunoprecipitation physical association 20080742 0.40 IntAct PPM1A phosphatase assay, pull down dephosphorylation reaction, direct interaction, physical association 23560844 0.61 IntAct, MINT PPP1CA phosphatase assay dephosphorylation reaction 12840032 0.44 IntAct, MINT PPP2CA phosphatase assay dephosphorylation reaction 12840032 0.44 IntAct, MINT PPP2R5C Biochemical Activity, protein kinase assay phosphorylation reaction, physical 16456541 0.44 BioGRID, IntAct, MINT PRPSAP1 Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct PTPN5 Affinity Capture-MS, Reconstituted Complex, pull down association, physical 27880917, 28330616, 9857190 0.35 BioGRID, IntAct PTPN7 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-localization, anti tag coimmunoprecipitation, phosphatase assay, proximity ligation assay, pull down dephosphorylation reaction, physical, physical association 10206983, 10415025, 10702794, 12592337, 25241761, 27880917 0.78 BioGRID, IntAct, MINT PTPRB phosphatase assay dephosphorylation reaction 12840032 0.44 IntAct, MINT PTPRJ anti tag coimmunoprecipitation, peptide array, phosphatase assay, pull down association 19494114 0.58 IntAct, MINT PTPRR Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-localization, Reconstituted Complex, fluorescence microscopy, phosphatase assay, proximity ligation assay, two hybrid array, two hybrid prey pooling approach colocalization, physical, physical association 10419510, 10601328, 25241761, 26186194, 27880917, 28514442, 9857190, 0.49, 0.62 BioGRID, IntAct, MINT PXN Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct RARA Affinity Capture-Western, Biochemical Activity, pull down association, physical 12048211, 25303530 0.35 BioGRID, IntAct RET Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct RPS6KA1 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, tandem affinity purification association, physical 10922375, 12594221, 12832467, 16039586, 23455922, 24623782, 9915826 0.35 BioGRID, IntAct RPS6KA2 Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, tandem affinity purification, two hybrid array, two hybrid prey pooling approach association, physical, physical association 12832467, 23602568, 25852190, 8939914, 0.71 BioGRID, IntAct RPS6KA3 Affinity Capture-MS, Affinity Capture-Western, Co-localization, Two-hybrid, proximity ligation assay, tandem affinity purification, two hybrid association, physical, physical association 12016217, 21988832, 23602568, 25241761, 8939914, 9915826 0.68 BioGRID, IntAct SCRIB protein kinase assay direct interaction 20622900 0.44 IntAct SHANK3 Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct SHC1 Affinity Capture-Western, fluorescent resonance energy transfer, isothermal titration calorimetry, pull down, x ray scattering direct interaction, physical, physical association 10996427, 23584453 0.40, 0.62 BioGRID, IntAct SMAD3 Affinity Capture-MS, Biochemical Activity, tandem affinity purification physical, physical association 18729074, 19914168 0.40 BioGRID, IntAct SNAI1 anti bait coimmunoprecipitation physical association 23644467 0.40 IntAct STAT5A Affinity Capture-Western, Co-localization, Reconstituted Complex, proximity ligation assay physical, physical association 10194762, 10996427, 25241761 0.40 BioGRID, IntAct SUPT20H Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct TNIK anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct TNIP1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, two hybrid, two hybrid array physical, physical association 12220502, 21988832, 26046540 0.49 BioGRID, IntAct TNIP2 two hybrid physical association 21988832 0.37 IntAct TP53 Affinity Capture-MS, Affinity Capture-Western, Co-localization, PCA, proximity ligation assay physical, physical association 10958792, 21147777, 21675959, 23443559, 25241761 0.40 BioGRID, IntAct VCAM1 cross-linking study association 22623428 0.35 IntAct YBX1 Biochemical Activity, experimental interaction detection phosphorylation reaction, physical 16198352 0.31 BioGRID, IntAct, MINT YBX3 Biochemical Activity, experimental interaction detection phosphorylation reaction, physical 16198352 0.31 BioGRID, IntAct, MINT