Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
JAK1	6190	COSM6962484,	prostate	carcinoma	p.?	Unknown	1:64867209-64867209,	PATHOGENIC	0.99814	28481359
JAK1	6190	COSM6962484,	prostate	carcinoma	p.?	Unknown	1:64867209-64867209,	PATHOGENIC	0.99814	28481359
JAK1	6190	COSM6957256,	penis	carcinoma	p.A1049V	Substitution - Missense	1:64836210-64836210,	PATHOGENIC	0.99796	28481359
JAK1	6190	COSM6946071,	large_intestine	carcinoma	p.?	Unknown	1:64869310-64869310,	PATHOGENIC	0.99771	28481359
JAK1	6190	COSM4771395,	breast	carcinoma	p.S295*	Substitution - Nonsense	1:64866972-64866972,	PATHOGENIC	0.99767	24185512
JAK1	6190	COSM5415929,	endometrium	carcinoma	p.E284*	Substitution - Nonsense	1:64867006-64867006,	PATHOGENIC	0.99767	25233892
JAK1	6190	COSM6127283,	cervix	carcinoma	p.E284K	Substitution - Missense	1:64867006-64867006,	PATHOGENIC	0.99748	28481359
JAK1	6190	COSM6959386,	central_nervous_system	glioma	p.?	Unknown	1:64835507-64835507,	PATHOGENIC	0.99698	28481359
JAK1	6190	COSM6975753,	skin	carcinoma	p.E210K	Substitution - Missense	1:64869330-64869330,	PATHOGENIC	0.99679	28481359
JAK1	6190	COSM6920852,	breast	carcinoma	p.W1047*	Substitution - Nonsense	1:64836215-64836215,	PATHOGENIC	0.99659	28481359
JAK1	6190	COSM6974034,	biliary_tract	carcinoma	p.E883*	Substitution - Nonsense	1:64841247-64841247,	PATHOGENIC	0.99578	28481359
JAK1	6190	COSM4943283,	breast	carcinoma	p.S154*	Substitution - Nonsense	1:64873392-64873392,	PATHOGENIC	0.99578	24185512
JAK1	6190	COSM5448879,	large_intestine	carcinoma	p.P148H	Substitution - Missense	1:64873410-64873410,	PATHOGENIC	0.99561	28481359
JAK1	6190	COSM5609179,	skin	malignant_melanoma	p.P148T	Substitution - Missense	1:64873411-64873411,	PATHOGENIC	0.99561	26343386
JAK1	6190	COSM41774,	prostate	carcinoma	p.T593M	Substitution - Missense	1:64847653-64847653,	PATHOGENIC	0.99555	28481359
JAK1	6190	COSM41774,	large_intestine	carcinoma	p.T593M	Substitution - Missense	1:64847653-64847653,	PATHOGENIC	0.99555	19900094
JAK1	6190	COSM5609184,	NS	malignant_melanoma	p.P222S	Substitution - Missense	1:64867192-64867192,	PATHOGENIC	0.99536	28481359
JAK1	6190	COSM5609184,	skin	malignant_melanoma	p.P222S	Substitution - Missense	1:64867192-64867192,	PATHOGENIC	0.99536	26343386
JAK1	6190	COSM5566982,	thyroid	carcinoma	p.R873H	Substitution - Missense	1:64841276-64841276,	PATHOGENIC	0.99522	28481359
JAK1	6190	COSM6933817,	lung	carcinoma	p.C1131F	Substitution - Missense	1:64834635-64834635,	PATHOGENIC	0.9948	28481359
JAK1	6190	COSM6974527,	testis	germ_cell_tumour	p.G600E	Substitution - Missense	1:64847632-64847632,	PATHOGENIC	0.99474	28481359
JAK1	6190	COSM6948081,	prostate	carcinoma	p.D121N	Substitution - Missense	1:64873492-64873492,	PATHOGENIC	0.99473	28481359
JAK1	6190	COSM6948081,	prostate	carcinoma	p.D121N	Substitution - Missense	1:64873492-64873492,	PATHOGENIC	0.99473	28481359
JAK1	6190	COSM6948081,	large_intestine	carcinoma	p.D121N	Substitution - Missense	1:64873492-64873492,	PATHOGENIC	0.99473	28481359
JAK1	6190	COSM6906682,	stomach	carcinoma	p.H117R	Substitution - Missense	1:64873503-64873503,	PATHOGENIC	0.99457	29420467
JAK1	6190	COSM6920851,	breast	carcinoma	p.S1066C	Substitution - Missense	1:64836159-64836159,	PATHOGENIC	0.99455	28481359
JAK1	6190	COSM6909689,	breast	carcinoma	p.S1062C	Substitution - Missense	1:64836171-64836171,	PATHOGENIC	0.99455	28481359
JAK1	6190	COSM4818990,	endometrium	carcinoma	p.E314K	Substitution - Missense	1:64866916-64866916,	PATHOGENIC	0.99446	27159395
JAK1	6190	COSM6937580,	urinary_tract	carcinoma	p.T1070N	Substitution - Missense	1:64836147-64836147,	PATHOGENIC	0.9941	28481359
JAK1	6190	COSM4606336,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T901R	Substitution - Missense	1:64839743-64839743,	PATHOGENIC	0.99403	22237106
JAK1	6190	COSM6941322,	breast	carcinoma	p.H628P	Substitution - Missense	1:64847548-64847548,	PATHOGENIC	0.99398	28481359
JAK1	6190	COSM6921484,	lung	carcinoma	p.V194F	Substitution - Missense	1:64869378-64869378,	PATHOGENIC	0.99373	28481359
JAK1	6190	COSM6916975,	breast	carcinoma	p.M192I	Substitution - Missense	1:64869382-64869382,	PATHOGENIC	0.99373	28481359
JAK1	6190	COSM6924985,	thyroid	carcinoma	p.S1062F	Substitution - Missense	1:64836171-64836171,	PATHOGENIC	0.99318	28481359
JAK1	6190	COSM6973448,	upper_aerodigestive_tract	carcinoma	p.P836S	Substitution - Missense	1:64841499-64841499,	PATHOGENIC	0.99254	28481359
JAK1	6190	COSM6909143,	breast	carcinoma	p.L1010R	Substitution - Missense	1:64838043-64838043,	PATHOGENIC	0.99252	28481359
JAK1	6190	COSM6909143,	breast	carcinoma	p.L1010R	Substitution - Missense	1:64838043-64838043,	PATHOGENIC	0.99252	28481359
JAK1	6190	COSM6924117,	breast	carcinoma	p.E864*	Substitution - Nonsense	1:64841304-64841304,	PATHOGENIC	0.9925	28481359
JAK1	6190	COSM6967874,	lung	carcinoma	p.H934Y	Substitution - Missense	1:64839645-64839645,	PATHOGENIC	0.99238	28481359
JAK1	6190	COSM240269,	thyroid	carcinoma	p.E188K	Substitution - Missense	1:64869396-64869396,	PATHOGENIC	0.99237	28481359
JAK1	6190	COSM6984305,	endometrium	carcinoma	p.E587K	Substitution - Missense	1:64847672-64847672,	PATHOGENIC	0.99232	28481359
JAK1	6190	COSM6970130,	lung	carcinoma	p.?	Unknown	1:64836096-64836096,	PATHOGENIC	0.99223	28481359
JAK1	6190	COSM6914980,	lung	carcinoma	p.P861T	Substitution - Missense	1:64841313-64841313,	PATHOGENIC	0.99174	28481359
JAK1	6190	COSM6962551,	lung	carcinoma	p.N187S	Substitution - Missense	1:64869398-64869398,	PATHOGENIC	0.99162	28481359
JAK1	6190	COSM6976968,	lung	carcinoma	p.D1003H	Substitution - Missense	1:64838065-64838065,	PATHOGENIC	0.99161	28481359
JAK1	6190	COSM1602623,	liver	carcinoma	p.L910P	Substitution - Missense	1:64839716-64839716,	PATHOGENIC	0.99154	28481359
JAK1	6190	COSM4169978,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G1097D	Substitution - Missense	1:64835475-64835475,	PATHOGENIC	0.99095	24345752
JAK1	6190	COSM4169978,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G1097D	Substitution - Missense	1:64835475-64835475,	PATHOGENIC	0.99095	27369867
JAK1	6190	COSM6849677,	breast	carcinoma	p.S1043I	Substitution - Missense	1:64837944-64837944,	PATHOGENIC	0.99091	28270497
JAK1	6190	COSM6920853,	breast	carcinoma	p.R1007T	Substitution - Missense	1:64838052-64838052,	PATHOGENIC	0.99062	28481359
JAK1	6190	COSM6935151,	endometrium	carcinoma	p.D844Y	Substitution - Missense	1:64841475-64841475,	PATHOGENIC	0.99	28481359
JAK1	6190	COSM6926101,	breast	carcinoma	p.R843I	Substitution - Missense	1:64841477-64841477,	PATHOGENIC	0.99	28481359
JAK1	6190	COSM6921717,	central_nervous_system	glioma	p.N241Y	Substitution - Missense	1:64867135-64867135,	PATHOGENIC	0.98983	28481359
JAK1	6190	COSM6911938,	large_intestine	carcinoma	p.E609*	Substitution - Nonsense	1:64847606-64847606,	PATHOGENIC	0.98916	28481359
JAK1	6190	COSM6957906,	upper_aerodigestive_tract	carcinoma	p.L820Q	Substitution - Missense	1:64841546-64841546,	PATHOGENIC	0.98905	28481359
JAK1	6190	COSM6979549,	large_intestine	carcinoma	p.R1002Q	Substitution - Missense	1:64838067-64838067,	PATHOGENIC	0.98881	28481359
JAK1	6190	COSM4990581,	skin	carcinoma	p.P960L	Substitution - Missense	1:64838553-64838553,	PATHOGENIC	0.98873	25589618
JAK1	6190	COSM4990582,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P960S	Substitution - Missense	1:64838554-64838554,	PATHOGENIC	0.98873	28410228
JAK1	6190	COSM4990582,	skin	carcinoma	p.P960S	Substitution - Missense	1:64838554-64838554,	PATHOGENIC	0.98873	25589618
JAK1	6190	COSM4990582,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P960S	Substitution - Missense	1:64838554-64838554,	PATHOGENIC	0.98873	24056718
JAK1	6190	COSM6917601,	skin	malignant_melanoma	p.Y967H	Substitution - Missense	1:64838533-64838533,	PATHOGENIC	0.9879	28481359
JAK1	6190	COSM6907136,	urinary_tract	carcinoma	p.E287Q	Substitution - Missense	1:64866997-64866997,	PATHOGENIC	0.98781	29420467
JAK1	6190	COSM6947308,	prostate	carcinoma	p.Q1143*	Substitution - Nonsense	1:64834600-64834600,	PATHOGENIC	0.98774	28481359
JAK1	6190	COSM6946070,	large_intestine	carcinoma	p.?	Unknown	1:64850911-64850911,	PATHOGENIC	0.9877	28481359
JAK1	6190	COSM6946068,	large_intestine	carcinoma	p.G1148*	Substitution - Nonsense	1:64834585-64834585,	PATHOGENIC	0.98739	28481359
JAK1	6190	COSM6935150,	endometrium	carcinoma	p.I928F	Substitution - Missense	1:64839663-64839663,	PATHOGENIC	0.98709	28481359
JAK1	6190	COSM6942878,	lung	carcinoma	p.E662Q	Substitution - Missense	1:64846652-64846652,	PATHOGENIC	0.98705	28481359
JAK1	6190	COSM6958244,	lung	carcinoma	p.E913K	Substitution - Missense	1:64839708-64839708,	PATHOGENIC	0.98699	28481359
JAK1	6190	COSM6981889,	endometrium	carcinoma	p.E1133*	Substitution - Nonsense	1:64834630-64834630,	PATHOGENIC	0.9868	28481359
JAK1	6190	COSM2239136,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y654F	Substitution - Missense	1:64846675-64846675,	PATHOGENIC	0.98661	26415585
JAK1	6190	COSM6919715,	soft_tissue	leiomyosarcoma	p.?	Unknown	1:64838105-64838105,	PATHOGENIC	0.98616	28481359
JAK1	6190	COSM6954161,	large_intestine	carcinoma	p.K267E	Substitution - Missense	1:64867057-64867057,	PATHOGENIC	0.98611	28481359
JAK1	6190	COSM5705527,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T901A	Substitution - Missense	1:64839744-64839744,	PATHOGENIC	0.98589	26437031
JAK1	6190	COSM6944124,	urinary_tract	carcinoma	p.S1080L	Substitution - Missense	1:64836117-64836117,	PATHOGENIC	0.9854	28481359
JAK1	6190	COSM6944124,	urinary_tract	carcinoma	p.S1080L	Substitution - Missense	1:64836117-64836117,	PATHOGENIC	0.9854	28481359
JAK1	6190	COSM6948223,	central_nervous_system	glioma	p.E850K	Substitution - Missense	1:64841457-64841457,	PATHOGENIC	0.98504	28481359
JAK1	6190	COSM6444841,	endometrium	carcinoma	p.E447*	Substitution - Nonsense	1:64857775-64857775,	PATHOGENIC	0.9847	27159395
JAK1	6190	COSM133112,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D604Y	Substitution - Missense	1:64847621-64847621,	PATHOGENIC	0.9847	21880637
JAK1	6190	COSM911558,	endometrium	carcinoma	p.E668*	Substitution - Nonsense	1:64845626-64845626,	PATHOGENIC	0.98466	27159395
JAK1	6190	COSM6938433,	large_intestine	carcinoma	p.E706K	Substitution - Missense	1:64844889-64844889,	PATHOGENIC	0.98418	28481359
JAK1	6190	COSM6953254,	urinary_tract	carcinoma	p.E849K	Substitution - Missense	1:64841460-64841460,	PATHOGENIC	0.98371	28481359
JAK1	6190	COSM1343910,	large_intestine	carcinoma	p.A449T	Substitution - Missense	1:64857769-64857769,	PATHOGENIC	0.98342	28481359
JAK1	6190	COSM6196690,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A639G	Substitution - Missense	1:64846720-64846720,	PATHOGENIC	0.98342	28410228
JAK1	6190	COSM6933526,	lung	carcinoma	p.?	Unknown	1:64844217-64844217,	PATHOGENIC	0.98327	28481359
JAK1	6190	COSM48448,	lung	carcinoma	p.M828I	Substitution - Missense	1:64841521-64841521,	PATHOGENIC	0.98321	18948947
JAK1	6190	COSM6917248,	breast	carcinoma	p.Q986*	Substitution - Nonsense	1:64838476-64838476,	PATHOGENIC	0.98228	28481359
JAK1	6190	COSM6944304,	NS	carcinoma	p.T558A	Substitution - Missense	1:64850887-64850887,	PATHOGENIC	0.98196	28481359
JAK1	6190	COSM4606338,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1012G	Substitution - Missense	1:64838037-64838037,	PATHOGENIC	0.98194	25430085
JAK1	6190	COSM4606338,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1012G	Substitution - Missense	1:64838037-64838037,	PATHOGENIC	0.98194	22237106
JAK1	6190	COSM6196689,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S646P	Substitution - Missense	1:64846700-64846700,	PATHOGENIC	0.98155	28410228
JAK1	6190	COSM6196689,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S646P	Substitution - Missense	1:64846700-64846700,	PATHOGENIC	0.98155	28410228
JAK1	6190	COSM6196689,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S646P	Substitution - Missense	1:64846700-64846700,	PATHOGENIC	0.98155	28410228
JAK1	6190	COSM41754,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R879C	Substitution - Missense	1:64841259-64841259,	PATHOGENIC	0.98147	18362173
JAK1	6190	COSM41754,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R879C	Substitution - Missense	1:64841259-64841259,	PATHOGENIC	0.98147	25595890
JAK1	6190	COSM6960756,	stomach	carcinoma	p.V746A	Substitution - Missense	1:64844768-64844768,	PATHOGENIC	0.9803	28481359
JAK1	6190	COSM6960756,	stomach	carcinoma	p.V746A	Substitution - Missense	1:64844768-64844768,	PATHOGENIC	0.9803	28481359
JAK1	6190	COSM6946069,	large_intestine	carcinoma	p.D728N	Substitution - Missense	1:64844823-64844823,	PATHOGENIC	0.98003	28481359
JAK1	6190	COSM6974834,	large_intestine	carcinoma	p.M477T	Substitution - Missense	1:64857684-64857684,	PATHOGENIC	0.97983	28481359
JAK1	6190	COSM6930206,	skin	malignant_melanoma	p.I444V	Substitution - Missense	1:64860109-64860109,	PATHOGENIC	0.97959	28481359
JAK1	6190	COSM96541,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703T	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97928	21390130
JAK1	6190	COSM96541,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703T	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97928	21390130
JAK1	6190	COSM6958530,	skin	malignant_melanoma	p.?	Unknown	1:64845512-64845512,	PATHOGENIC	0.97882	28481359
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	22237106
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	26437031
JAK1	6190	COSM305942,	liver	carcinoma	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	28481359
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	23733339
JAK1	6190	COSM305942,	liver	carcinoma	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	28481359
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	26437031
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	27288520
JAK1	6190	COSM6974430,	upper_aerodigestive_tract	carcinoma	p.E637Q	Substitution - Missense	1:64846727-64846727,	PATHOGENIC	0.97812	28481359
JAK1	6190	COSM6907429,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M824L	Substitution - Missense	1:64841535-64841535,	PATHOGENIC	0.97667	24056718
JAK1	6190	COSM6995445,	ovary	germ_cell_tumour	p.K580E	Substitution - Missense	1:64850821-64850821,	PATHOGENIC	0.97638	28954785
JAK1	6190	COSM41757,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.V658F	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.97549	21680795
JAK1	6190	COSM41757,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.V658F	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.97549	18559588
JAK1	6190	COSM41757,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.V658F	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.97549	18559588
JAK1	6190	COSM41757,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.V658F	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.97549	18559588
JAK1	6190	COSM312102,	lung	carcinoma	p.K140*	Substitution - Nonsense	1:64873435-64873435,	PATHOGENIC	0.97521	22941188
JAK1	6190	COSM94556,	penis	carcinoma	p.E637K	Substitution - Missense	1:64846727-64846727,	PATHOGENIC	0.97454	28481359
JAK1	6190	COSM94556,	breast	carcinoma	p.E637K	Substitution - Missense	1:64846727-64846727,	PATHOGENIC	0.97454	20668451
JAK1	6190	COSM6920980,	prostate	carcinoma	p.R826C	Substitution - Missense	1:64841529-64841529,	PATHOGENIC	0.97419	28481359
JAK1	6190	COSM6920980,	prostate	carcinoma	p.R826C	Substitution - Missense	1:64841529-64841529,	PATHOGENIC	0.97419	28481359
JAK1	6190	COSM5989716,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M679L	Substitution - Missense	1:64845593-64845593,	PATHOGENIC	0.97378	26648538
JAK1	6190	COSM6973687,	prostate	carcinoma	p.C424F	Substitution - Missense	1:64860168-64860168,	PATHOGENIC	0.97377	28481359
JAK1	6190	COSM5047136,	oesophagus	carcinoma	p.W363R	Substitution - Missense	1:64864876-64864876,	PATHOGENIC	0.97357	24686850
JAK1	6190	COSM2239144,	breast	carcinoma	p.A428P	Substitution - Missense	1:64860157-64860157,	PATHOGENIC	0.97355	28481359
JAK1	6190	COSM6494356,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L1053V	Substitution - Missense	1:64836199-64836199,	PATHOGENIC	0.97193	27534895
JAK1	6190	COSM6494356,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L1053V	Substitution - Missense	1:64836199-64836199,	PATHOGENIC	0.97193	27534895
JAK1	6190	COSM7002460,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.V658I	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.9713	28550193
JAK1	6190	COSM6910406,	testis	germ_cell_tumour	p.T478A	Substitution - Missense	1:64857682-64857682,	PATHOGENIC	0.97103	28481359
JAK1	6190	COSM5762889,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I597M	Substitution - Missense	1:64847640-64847640,	PATHOGENIC	0.97036	27127180
JAK1	6190	COSM6928863,	central_nervous_system	glioma	p.V1011I	Substitution - Missense	1:64838041-64838041,	PATHOGENIC	0.96941	28481359
JAK1	6190	COSM6934408,	urinary_tract	carcinoma	p.R414Q	Substitution - Missense	1:64860198-64860198,	PATHOGENIC	0.9693	28481359
JAK1	6190	COSM911571,	oesophagus	carcinoma	p.R174*	Substitution - Nonsense	1:64869438-64869438,	PATHOGENIC	0.96928	28481359
JAK1	6190	COSM911571,	skin	carcinoma	p.R174*	Substitution - Nonsense	1:64869438-64869438,	PATHOGENIC	0.96928	28481359
JAK1	6190	COSM911571,	endometrium	carcinoma	p.R174*	Substitution - Nonsense	1:64869438-64869438,	PATHOGENIC	0.96928	25233892
JAK1	6190	COSM911571,	breast	carcinoma	p.R174*	Substitution - Nonsense	1:64869438-64869438,	PATHOGENIC	0.96928	28481359
JAK1	6190	COSM6948457,	urinary_tract	carcinoma	p.V1124I	Substitution - Missense	1:64834657-64834657,	PATHOGENIC	0.96902	28481359
JAK1	6190	COSM6962781,	central_nervous_system	glioma	p.D410N	Substitution - Missense	1:64860211-64860211,	PATHOGENIC	0.96868	28481359
JAK1	6190	COSM6930134,	prostate	carcinoma	p.V651M	Substitution - Missense	1:64846685-64846685,	PATHOGENIC	0.96804	28481359
JAK1	6190	COSM133113,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.F734L	Substitution - Missense	1:64844803-64844803,	PATHOGENIC	0.96757	21880637
JAK1	6190	COSM5990834,	liver	other	p.A723D	Substitution - Missense	1:64844837-64844837,	PATHOGENIC	0.96745	24735922
JAK1	6190	COSM41751,	endometrium	carcinoma	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	28481359
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	22425895
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	18362173
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	25854815
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	22425895
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	18362173
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	22425895
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	18362173
JAK1	6190	COSM41751,	urinary_tract	carcinoma	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	28481359
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	25595890
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	18362173
JAK1	6190	COSM4990585,	skin	carcinoma	p.T470I	Substitution - Missense	1:64857705-64857705,	PATHOGENIC	0.96605	25589618
JAK1	6190	COSM303855,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S646F	Substitution - Missense	1:64846699-64846699,	PATHOGENIC	0.96601	21680795
JAK1	6190	COSM6986431,	lung	carcinoma	p.K218N	Substitution - Missense	1:64867202-64867202,	PATHOGENIC	0.96558	28481359
JAK1	6190	COSM464865,	endometrium	carcinoma	p.A984V	Substitution - Missense	1:64838481-64838481,	PATHOGENIC	0.96393	28481359
JAK1	6190	COSM1717657,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.I377K	Substitution - Missense	1:64864833-64864833,	PATHOGENIC	0.96352	23603912
JAK1	6190	COSM6977897,	large_intestine	carcinoma	p.T745M	Substitution - Missense	1:64844771-64844771,	PATHOGENIC	0.96303	28481359
JAK1	6190	COSM6936372,	lung	carcinoma	p.R804T	Substitution - Missense	1:64841594-64841594,	PATHOGENIC	0.95963	28481359
JAK1	6190	COSM5609183,	skin	malignant_melanoma	p.P131L	Substitution - Missense	1:64873461-64873461,	PATHOGENIC	0.95943	26343386
JAK1	6190	COSM95619,	breast	carcinoma	p.W467*	Substitution - Nonsense	1:64857713-64857713,	PATHOGENIC	0.95846	20668451
JAK1	6190	COSM41759,	lung	carcinoma	p.T782M	Substitution - Missense	1:64844122-64844122,	PATHOGENIC	0.95841	18559588
JAK1	6190	COSM5609180,	skin	malignant_melanoma	p.L150F	Substitution - Missense	1:64873405-64873405,	PATHOGENIC	0.95839	26343386
JAK1	6190	COSM6936858,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L403W	Substitution - Missense	1:64860231-64860231,	PATHOGENIC	0.95676	28481359
JAK1	6190	COSM5415928,	large_intestine	carcinoma	p.V427M	Substitution - Missense	1:64860160-64860160,	PATHOGENIC	0.95621	28481359
JAK1	6190	COSM5415928,	endometrium	carcinoma	p.V427M	Substitution - Missense	1:64860160-64860160,	PATHOGENIC	0.95621	25233892
JAK1	6190	COSM5095534,	thymus	thymic_carcinoma	p.?	Unknown	1:64883276-64883276,	PATHOGENIC	0.95506	24974848
JAK1	6190	COSM5745651,	large_intestine	carcinoma	p.R1113C	Substitution - Missense	1:64835428-64835428,	PATHOGENIC	0.95315	28481359
JAK1	6190	COSM4990583,	skin	carcinoma	p.E751K	Substitution - Missense	1:64844754-64844754,	PATHOGENIC	0.95268	25589618
JAK1	6190	COSM6928864,	central_nervous_system	glioma	p.S574N	Substitution - Missense	1:64850838-64850838,	PATHOGENIC	0.95225	28481359
JAK1	6190	COSM6924118,	lung	carcinoma	p.W777C	Substitution - Missense	1:64844136-64844136,	PATHOGENIC	0.95174	28481359
JAK1	6190	COSM6924118,	breast	carcinoma	p.W777C	Substitution - Missense	1:64844136-64844136,	PATHOGENIC	0.95174	28481359
JAK1	6190	COSM911551,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.F958C	Substitution - Missense	1:64838559-64838559,	PATHOGENIC	0.95043	26437031
JAK1	6190	COSM3734693,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R659C	Substitution - Missense	1:64846661-64846661,	PATHOGENIC	0.95028	24497536
JAK1	6190	COSM6957258,	penis	carcinoma	p.N497H	Substitution - Missense	1:64855668-64855668,	PATHOGENIC	0.94991	28481359
JAK1	6190	COSM5945903,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y652N	Substitution - Missense	1:64846682-64846682,	PATHOGENIC	0.94983	26773734
JAK1	6190	COSM6981134,	endometrium	carcinoma	p.R873C	Substitution - Missense	1:64841277-64841277,	PATHOGENIC	0.94937	28481359
JAK1	6190	COSM6961253,	upper_aerodigestive_tract	carcinoma	p.I756F	Substitution - Missense	1:64844201-64844201,	PATHOGENIC	0.94935	28481359
JAK1	6190	COSM6910167,	lung	carcinoma	p.V261L	Substitution - Missense	1:64867075-64867075,	PATHOGENIC	0.94887	28481359
JAK1	6190	COSM6982246,	endometrium	carcinoma	p.C481*	Substitution - Nonsense	1:64857671-64857671,	PATHOGENIC	0.94838	28481359
JAK1	6190	COSM6978650,	breast	carcinoma	p.L235V	Substitution - Missense	1:64867153-64867153,	PATHOGENIC	0.94816	28481359
JAK1	6190	COSM6978491,	endometrium	carcinoma	p.V1101I	Substitution - Missense	1:64835464-64835464,	PATHOGENIC	0.94775	28481359
JAK1	6190	COSM911575,	large_intestine	carcinoma	p.?	Unknown	1:64883276-64883276,	PATHOGENIC	0.94766	28481359
JAK1	6190	COSM6938432,	large_intestine	carcinoma	p.D775N	Substitution - Missense	1:64844144-64844144,	PATHOGENIC	0.94761	28481359
JAK1	6190	COSM6909299,	lung	carcinoma	p.E58K	Substitution - Missense	1:64883310-64883310,	PATHOGENIC	0.94758	28481359
JAK1	6190	COSM6978873,	kidney	carcinoma	p.M462I	Substitution - Missense	1:64857728-64857728,	PATHOGENIC	0.9473	28481359
JAK1	6190	COSM6914226,	skin	carcinoma	p.R454W	Substitution - Missense	1:64857754-64857754,	PATHOGENIC	0.94625	28481359
JAK1	6190	COSM6915320,	skin	carcinoma	p.?	Unknown	1:64844216-64844216,	PATHOGENIC	0.94584	28481359
JAK1	6190	COSM6914547,	prostate	carcinoma	p.R128C	Substitution - Missense	1:64873471-64873471,	PATHOGENIC	0.9431	28481359
JAK1	6190	COSM6913928,	salivary_gland	carcinoma	p.L1104F	Substitution - Missense	1:64835455-64835455,	PATHOGENIC	0.94304	28481359
JAK1	6190	COSM911545,	endometrium	carcinoma	p.R1139W	Substitution - Missense	1:64834612-64834612,	PATHOGENIC	0.9422	28481359
JAK1	6190	COSM5609181,	skin	malignant_melanoma	p.Q1098Q	Substitution - coding silent	1:64835471-64835471,	PATHOGENIC	0.9415	26343386
JAK1	6190	COSM1667603,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E897K	Substitution - Missense	1:64839756-64839756,	PATHOGENIC	0.94138	25595890
JAK1	6190	COSM5047430,	oesophagus	carcinoma	p.E1123Q	Substitution - Missense	1:64835398-64835398,	PATHOGENIC	0.93831	24686850
JAK1	6190	COSM5415927,	endometrium	carcinoma	p.E791K	Substitution - Missense	1:64844096-64844096,	PATHOGENIC	0.93761	25233892
JAK1	6190	COSM5415927,	large_intestine	carcinoma	p.E791K	Substitution - Missense	1:64844096-64844096,	PATHOGENIC	0.93761	28481359
JAK1	6190	COSM41776,	liver	carcinoma	p.V645F	Substitution - Missense	1:64846703-64846703,	PATHOGENIC	0.93606	19239328
JAK1	6190	COSM6922191,	soft_tissue	gastrointestinal_stromal_tumour	p.R997Q	Substitution - Missense	1:64838082-64838082,	PATHOGENIC	0.93595	28481359
JAK1	6190	COSM1579122,	lung	carcinoma	p.Q207L	Substitution - Missense	1:64869338-64869338,	PATHOGENIC	0.93504	28481359
JAK1	6190	COSM6952092,	large_intestine	carcinoma	p.D796Y	Substitution - Missense	1:64844081-64844081,	PATHOGENIC	0.93421	28481359
JAK1	6190	COSM6959923,	lung	carcinoma	p.D388N	Substitution - Missense	1:64864801-64864801,	PATHOGENIC	0.93105	28481359
JAK1	6190	COSM6919097,	endometrium	carcinoma	p.L702V	Substitution - Missense	1:64845524-64845524,	PATHOGENIC	0.93092	28481359
JAK1	6190	COSM6964229,	prostate	carcinoma	p.R549*	Substitution - Nonsense	1:64855512-64855512,	PATHOGENIC	0.92845	28481359
JAK1	6190	COSM6981475,	large_intestine	carcinoma	p.R659S	Substitution - Missense	1:64846661-64846661,	PATHOGENIC	0.92761	28481359
JAK1	6190	COSM6221446,	large_intestine	carcinoma	p.V656I	Substitution - Missense	1:64846670-64846670,	PATHOGENIC	0.92593	28481359
JAK1	6190	COSM6221446,	prostate	carcinoma	p.V656I	Substitution - Missense	1:64846670-64846670,	PATHOGENIC	0.92593	28481359
JAK1	6190	COSM6006332,	skin	adnexal_tumour	p.E1123K	Substitution - Missense	1:64835398-64835398,	PATHOGENIC	0.91943	27287813
JAK1	6190	COSM1645298,	oesophagus	carcinoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	28481359
JAK1	6190	COSM1645298,	large_intestine	carcinoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	23700467
JAK1	6190	COSM1645298,	large_intestine	carcinoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	23700467
JAK1	6190	COSM1645298,	soft_tissue	liposarcoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	29420467
JAK1	6190	COSM1645298,	soft_tissue	liposarcoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	28481359
JAK1	6190	COSM1645298,	large_intestine	carcinoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	28481359
JAK1	6190	COSM6949371,	breast	carcinoma	p.E1029K	Substitution - Missense	1:64837987-64837987,	PATHOGENIC	0.91615	28481359
JAK1	6190	COSM6949371,	central_nervous_system	glioma	p.E1029K	Substitution - Missense	1:64837987-64837987,	PATHOGENIC	0.91615	28481359
JAK1	6190	COSM5878734,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683T	Substitution - Missense	1:64845580-64845580,	PATHOGENIC	0.91342	27288520
JAK1	6190	COSM6964228,	prostate	carcinoma	p.R577W	Substitution - Missense	1:64850830-64850830,	PATHOGENIC	0.90962	28481359
JAK1	6190	COSM41758,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L783F	Substitution - Missense	1:64844120-64844120,	PATHOGENIC	0.90957	18559588
JAK1	6190	COSM6958243,	lung	carcinoma	p.G915E	Substitution - Missense	1:64839701-64839701,	PATHOGENIC	0.90925	28481359
JAK1	6190	COSM6957794,	large_intestine	carcinoma	p.K797R	Substitution - Missense	1:64844077-64844077,	PATHOGENIC	0.90854	28481359
JAK1	6190	COSM5574248,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L710V	Substitution - Missense	1:64844877-64844877,	PATHOGENIC	0.90792	26415585
JAK1	6190	COSM3741347,	upper_aerodigestive_tract	carcinoma	p.R724C	Substitution - Missense	1:64844835-64844835,	PATHOGENIC	0.90448	28581676
JAK1	6190	COSM6948224,	central_nervous_system	glioma	p.S518N	Substitution - Missense	1:64855604-64855604,	PATHOGENIC	0.90374	28481359
JAK1	6190	COSM4990586,	skin	carcinoma	p.K204N	Substitution - Missense	1:64869346-64869346,	PATHOGENIC	0.90302	25589618
JAK1	6190	COSM911557,	salivary_gland	carcinoma	p.R755*	Substitution - Nonsense	1:64844204-64844204,	PATHOGENIC	0.90015	28481359
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	soft_tissue	haemangioblastoma	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	25589003
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	soft_tissue	haemangioblastoma	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	25589003
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	soft_tissue	haemangioblastoma	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	25589003
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM6951533,	breast	carcinoma	p.R237S	Substitution - Missense	1:64867145-64867145,	PATHOGENIC	0.89966	28481359
JAK1	6190	COSM6937352,	lung	carcinoma	p.H434Y	Substitution - Missense	1:64860139-64860139,	PATHOGENIC	0.89795	28481359
JAK1	6190	COSM41775,	liver	carcinoma	p.Q644H	Substitution - Missense	1:64846704-64846704,	PATHOGENIC	0.89517	19239328
JAK1	6190	COSM6918599,	skin	carcinoma	p.S367F	Substitution - Missense	1:64864863-64864863,	PATHOGENIC	0.89424	28481359
JAK1	6190	COSM5754489,	central_nervous_system	glioma	p.E337K	Substitution - Missense	1:64864954-64864954,	PATHOGENIC	0.89346	28481359
JAK1	6190	COSM6494363,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L4V	Substitution - Missense	1:64883472-64883472,	PATHOGENIC	0.88732	27534895
JAK1	6190	COSM6494363,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L4V	Substitution - Missense	1:64883472-64883472,	PATHOGENIC	0.88732	27534895
JAK1	6190	COSM6957257,	penis	carcinoma	p.S961L	Substitution - Missense	1:64838550-64838550,	PATHOGENIC	0.88641	28481359
JAK1	6190	COSM48449,	lung	carcinoma	p.D660H	Substitution - Missense	1:64846658-64846658,	PATHOGENIC	0.88497	18948947
JAK1	6190	COSM6948112,	urinary_tract	carcinoma	p.M202I	Substitution - Missense	1:64869352-64869352,	PATHOGENIC	0.88391	28481359
JAK1	6190	COSM5019856,	breast	carcinoma	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	28270497
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	soft_tissue	haemangioblastoma	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	25589003
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	soft_tissue	haemangioblastoma	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	25589003
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	soft_tissue	haemangioblastoma	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	25589003
JAK1	6190	COSM312103,	lung	carcinoma	p.E401D	Substitution - Missense	1:64860236-64860236,	PATHOGENIC	0.8834	22941188
JAK1	6190	COSM6951534,	breast	carcinoma	p.R232S	Substitution - Missense	1:64867160-64867160,	PATHOGENIC	0.87961	28481359
JAK1	6190	COSM6942686,	kidney	carcinoma	p.E765Q	Substitution - Missense	1:64844174-64844174,	PATHOGENIC	0.87667	28481359
JAK1	6190	COSM6935776,	central_nervous_system	glioma	p.M299I	Substitution - Missense	1:64866959-64866959,	PATHOGENIC	0.87046	28481359
JAK1	6190	COSM6977408,	NS	malignant_melanoma	p.L720F	Substitution - Missense	1:64844847-64844847,	PATHOGENIC	0.86774	28481359
JAK1	6190	COSM4605021,	upper_aerodigestive_tract	carcinoma	p.Q980H	Substitution - Missense	1:64838492-64838492,	PATHOGENIC	0.85671	25056374
JAK1	6190	COSM4990587,	skin	carcinoma	p.G53E	Substitution - Missense	1:64883324-64883324,	PATHOGENIC	0.85043	25589618
JAK1	6190	COSM6941120,	NS	carcinoma	p.S380F	Substitution - Missense	1:64864824-64864824,	PATHOGENIC	0.8445	28481359
JAK1	6190	COSM6941120,	NS	carcinoma	p.S380F	Substitution - Missense	1:64864824-64864824,	PATHOGENIC	0.8445	28481359
JAK1	6190	COSM6956513,	endometrium	carcinoma	p.R577Q	Substitution - Missense	1:64850829-64850829,	PATHOGENIC	0.84071	28481359
JAK1	6190	COSM1717658,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S71C	Substitution - Missense	1:64879142-64879142,	PATHOGENIC	0.84022	23603912
JAK1	6190	COSM6922928,	central_nervous_system	glioma	p.T263M	Substitution - Missense	1:64867068-64867068,	PATHOGENIC	0.83214	28481359
JAK1	6190	COSM1717659,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.W564C	Substitution - Missense	1:64850867-64850867,	PATHOGENIC	0.82757	23603912
JAK1	6190	COSM6961824,	pancreas	carcinoid-endocrine_tumour	p.V409I	Substitution - Missense	1:64860214-64860214,	PATHOGENIC	0.82433	28481359
JAK1	6190	COSM6981890,	endometrium	carcinoma	p.F78S	Substitution - Missense	1:64879121-64879121,	PATHOGENIC	0.81591	28481359
JAK1	6190	COSM6941119,	NS	carcinoma	p.E1150K	Substitution - Missense	1:64834579-64834579,	PATHOGENIC	0.81482	28481359
JAK1	6190	COSM6941119,	NS	carcinoma	p.E1150K	Substitution - Missense	1:64834579-64834579,	PATHOGENIC	0.81482	28481359
JAK1	6190	COSM6959073,	urinary_tract	carcinoma	p.E354K	Substitution - Missense	1:64864903-64864903,	PATHOGENIC	0.81069	28481359
JAK1	6190	COSM6969013,	thyroid	carcinoma	p.E54Q	Substitution - Missense	1:64883322-64883322,	PATHOGENIC	0.80859	28481359
JAK1	6190	COSM6959387,	central_nervous_system	glioma	p.D246N	Substitution - Missense	1:64867120-64867120,	PATHOGENIC	0.80319	28481359
JAK1	6190	COSM1645390,	large_intestine	carcinoma	p.S367C	Substitution - Missense	1:64864863-64864863,	PATHOGENIC	0.80307	23700467
JAK1	6190	COSM6945203,	autonomic_ganglia	neuroblastoma	p.F779L	Substitution - Missense	1:64844130-64844130,	PATHOGENIC	0.80144	28481359
JAK1	6190	COSM6938450,	large_intestine	carcinoma	p.T863N	Substitution - Missense	1:64841306-64841306,	PATHOGENIC	0.79251	28481359
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	soft_tissue	haemangioblastoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	25589003
JAK1	6190	COSM5019852,	soft_tissue	haemangioblastoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	25589003
JAK1	6190	COSM5019852,	skin	malignant_melanoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	26343386
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	breast	carcinoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	28270497
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	soft_tissue	haemangioblastoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	25589003
JAK1	6190	COSM6923433,	large_intestine	carcinoma	p.R343W	Substitution - Missense	1:64864936-64864936,	PATHOGENIC	0.7879	28481359
JAK1	6190	COSM6923433,	central_nervous_system	glioma	p.R343W	Substitution - Missense	1:64864936-64864936,	PATHOGENIC	0.7879	28481359
JAK1	6190	COSM5415930,	endometrium	carcinoma	p.E54*	Substitution - Nonsense	1:64883322-64883322,	PATHOGENIC	0.76595	25233892
JAK1	6190	COSM6911729,	urinary_tract	carcinoma	p.E400K	Substitution - Missense	1:64860241-64860241,	PATHOGENIC	0.75386	28481359
JAK1	6190	COSM6936904,	skin	carcinoma	p.E54K	Substitution - Missense	1:64883322-64883322,	PATHOGENIC	0.74213	28481359
JAK1	6190	COSM96407,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.K648N	Substitution - Missense	1:64846692-64846692,	PATHOGENIC	0.73414	21551237
JAK1	6190	COSM6946968,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.E613K	Substitution - Missense	1:64847594-64847594,	PATHOGENIC	0.73371	28481359
JAK1	6190	COSM96408,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y652H	Substitution - Missense	1:64846682-64846682,	PATHOGENIC	0.71207	21551237
JAK1	6190	COSM96408,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Y652H	Substitution - Missense	1:64846682-64846682,	PATHOGENIC	0.71207	27288520
JAK1	6190	COSM96408,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y652H	Substitution - Missense	1:64846682-64846682,	PATHOGENIC	0.71207	26773734
JAK1	6190	COSM6930582,	skin	malignant_melanoma	p.R93C	Substitution - Missense	1:64879077-64879077,	NEUTRAL	0.46067	28481359
JAK1	6190	COSM6930582,	penis	carcinoma	p.R93C	Substitution - Missense	1:64879077-64879077,	NEUTRAL	0.46067	28481359
JAK1	6190	COSM6977127,	large_intestine	carcinoma	p.K606N	Substitution - Missense	1:64847613-64847613,	NEUTRAL	0.44893	28481359
JAK1	6190	COSM327049,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	1:64864978-64864978,	NEUTRAL	0.40938	22675565
JAK1	6190	COSM4604577,	upper_aerodigestive_tract	carcinoma	p.E614E	Substitution - coding silent	1:64847589-64847589,	NEUTRAL	0.39075	25056374
JAK1	6190	COSM5609182,	skin	malignant_melanoma	p.R577R	Substitution - coding silent	1:64850828-64850828,	NEUTRAL	0.36638	26343386
JAK1	6190	COSM1726762,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S729C	Substitution - Missense	1:64844820-64844820,	NEUTRAL	0.33636	25595890
JAK1	6190	COSM1726762,	liver	carcinoma	p.S729C	Substitution - Missense	1:64844820-64844820,	NEUTRAL	0.33636	28481359
JAK1	6190	COSM6494358,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R506H	Substitution - Missense	1:64855640-64855640,	NEUTRAL	0.33575	27534895
JAK1	6190	COSM6494358,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R506H	Substitution - Missense	1:64855640-64855640,	NEUTRAL	0.33575	27534895
JAK1	6190	COSM6929565,	testis	germ_cell_tumour	p.L105F	Substitution - Missense	1:64879041-64879041,	NEUTRAL	0.32996	28481359
JAK1	6190	COSM6973007,	large_intestine	carcinoma	p.R506S	Substitution - Missense	1:64855641-64855641,	NEUTRAL	0.31059	28481359
JAK1	6190	COSM6926296,	breast	carcinoma	p.G490A	Substitution - Missense	1:64855688-64855688,	NEUTRAL	0.30508	28481359
JAK1	6190	COSM6974196,	prostate	carcinoma	p.R69C	Substitution - Missense	1:64883277-64883277,	NEUTRAL	0.30447	28481359
JAK1	6190	COSM6946032,	breast	carcinoma	p.E83D	Substitution - Missense	1:64879105-64879105,	NEUTRAL	0.24838	28481359
JAK1	6190	COSM6005665,	prostate	carcinoma	p.L1108V	Substitution - Missense	1:64835443-64835443,	NEUTRAL	0.23588	20579941
JAK1	6190	COSM3491775,	skin	malignant_melanoma	p.S262S	Substitution - coding silent	1:64867070-64867070,	NEUTRAL	0.22978	26343386
JAK1	6190	COSM911565,	endometrium	carcinoma	p.S304L	Substitution - Missense	1:64866945-64866945,	NEUTRAL	0.21375	28481359
JAK1	6190	COSM911565,	urinary_tract	carcinoma	p.S304L	Substitution - Missense	1:64866945-64866945,	NEUTRAL	0.21375	28481359
JAK1	6190	COSM6920416,	large_intestine	carcinoma	p.V567I	Substitution - Missense	1:64850860-64850860,	NEUTRAL	0.20394	28481359
JAK1	6190	COSM6963786,	lung	carcinoma	p.G520V	Substitution - Missense	1:64855598-64855598,	NEUTRAL	0.13227	28481359
JAK1	6190	COSM6986310,	lung	carcinoma	p.R69H	Substitution - Missense	1:64879148-64879148,	NEUTRAL	0.12774	28481359
JAK1	6190	COSM6494360,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64869304-64869304,	NEUTRAL	0.11733	27534895
JAK1	6190	COSM6494360,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64869304-64869304,	NEUTRAL	0.11733	27534895
JAK1	6190	COSM6930065,	lung	carcinoma	p.Y568*	Substitution - Nonsense	1:64850855-64850855,	NEUTRAL	0.10206	28481359
JAK1	6190	COSM6986219,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.A862T	Substitution - Missense	1:64841310-64841310,	NEUTRAL	0.08403	28481359
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	soft_tissue	haemangioblastoma	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	25589003
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	soft_tissue	haemangioblastoma	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	25589003
JAK1	6190	COSM5020688,	soft_tissue	haemangioblastoma	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	25589003
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5019756,	soft_tissue	haemangioblastoma	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	25589003
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	soft_tissue	haemangioblastoma	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	25589003
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	breast	carcinoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	28270497
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	soft_tissue	haemangioblastoma	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	25589003
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	soft_tissue	haemangioblastoma	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	25589003
JAK1	6190	COSM5019905,	soft_tissue	haemangioblastoma	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	25589003
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	breast	carcinoma	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	28270497
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5020590,	soft_tissue	haemangioblastoma	p.Y568Y	Substitution - coding silent	1:64850855-64850855,	NEUTRAL	0.044	25589003
JAK1	6190	COSM6494357,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T1036T	Substitution - coding silent	1:64837964-64837964,	NEUTRAL	0.02117	27534895
JAK1	6190	COSM6494357,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T1036T	Substitution - coding silent	1:64837964-64837964,	NEUTRAL	0.02117	27534895
JAK1	6190	COSM6494357,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T1036T	Substitution - coding silent	1:64837964-64837964,	NEUTRAL	0.02117	27534895
JAK1	6190	COSM4990584,	skin	carcinoma	p.P566P	Substitution - coding silent	1:64850861-64850861,	NEUTRAL	0.01125	25589618
JAK1	6190	COSM6494359,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S304S	Substitution - coding silent	1:64866944-64866944,	NEUTRAL	0.00972	27534895
JAK1	6190	COSM6494361,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T96T	Substitution - coding silent	1:64879066-64879066,	NEUTRAL	0.00358	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	breast	carcinoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	28270497
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	breast	carcinoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	28270497
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM41840, COSM41841, COSM41842,	prostate	carcinoma	p.K142fs*26, p.L431fs*22, p.P430fs*2	Deletion - Frameshift, Insertion - Frameshift	1:64860149-64860150,	Info_not_available	Info_not_available	16102578
JAK1	6190	COSM41834, COSM41835, COSM41836, COSM41837, COSM41838, COSM41839,	soft_tissue	leiomyoma	p.G882E, p.M642I, p.S771C, p.V1045K, p.W1047G, p.Y463S	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	16474838
JAK1	6190	COSM41728,	central_nervous_system	glioma	p.L698L	Substitution - coding silent	Info_not_available	Info_not_available	Info_not_available	16618716
JAK1	6190	COSM41832, COSM41833,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T478S, p.V623A	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	18160671
JAK1	6190	COSM41749, COSM41750, COSM41752, COSM41753, COSM41755, COSM41756,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A634D, p.K204M, p.L653F, p.R879H, p.R879S, p.S512L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	18362173
JAK1	6190	COSM41760,	breast	carcinoma	p.H647Y	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	18559588
JAK1	6190	COSM48932,	lung	carcinoma	p.A428fs*25	Insertion - Frameshift	1:64860157-64860158,	Info_not_available	Info_not_available	18948947
JAK1	6190	COSM41829, COSM41830, COSM41831,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E966V, p.E966_K989del, p.S216fs*3	Deletion - Frameshift, Deletion - In frame, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19176360
JAK1	6190	COSM41761, COSM41762, COSM41763,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L624_R629>W, p.S646F, p.V658F	Complex - deletion inframe, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19470474
JAK1	6190	COSM41764, COSM41765, COSM41766, COSM41767,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H, p.R724Q, p.S512L, p.Y652H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19764985
JAK1	6190	COSM41763,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.V658F	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19838194
JAK1	6190	COSM1560531, COSM6005666,	prostate	carcinoma	p.K860fs*16, p.P430fs*2	Deletion - Frameshift	1:64841321-64841321, 1:64860150-64860150,	Info_not_available	Info_not_available	20579941
JAK1	6190	COSM303810,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L624_R629>W	Complex - deletion inframe	1:64847546-64847560,	Info_not_available	Info_not_available	21680795
JAK1	6190	COSM133114,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1012fs*2	Insertion - Frameshift	1:64838039-64838040,	Info_not_available	Info_not_available	21880637
JAK1	6190	COSM4606337,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1012_S1013insK	Insertion - In frame	Info_not_available	Info_not_available	Info_not_available	22237106
JAK1	6190	COSM41765,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y652H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	22438252
JAK1	6190	COSM5945920, COSM5945922, COSM5945924, COSM5945950,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F635_F636>F, p.I952V, p.N714fs*?, p.S383G	Complex - deletion inframe, Frameshift, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	23153540
JAK1	6190	COSM1666870,	urinary_tract	carcinoma	p.D660H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	23887298
JAK1	6190	COSM1717467, COSM1717468, COSM41756,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L653F, p.R629_D630del	Deletion - In frame, Substitution - Missense	1:64847540-64847545, 1:64847542-64847547,	Info_not_available	Info_not_available	24048415
JAK1	6190	COSM5049732,	oesophagus	carcinoma	p.G916fs*4	Deletion - Frameshift	1:64839700-64839700,	Info_not_available	Info_not_available	24686850
JAK1	6190	COSM41762, COSM41763, COSM4989842, COSM4989843, COSM4989844,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.C787F, p.K1026E, p.S646F, p.V658F, p.V658I	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25207766
JAK1	6190	COSM5415931,	ovary	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	25233892
JAK1	6190	COSM5024893,	breast	carcinoma	p.E223fs*11	Deletion - Frameshift	1:64867166-64867187,	Info_not_available	Info_not_available	25850943
JAK1	6190	COSM5751190, COSM5751191, COSM5751286, COSM5751475, COSM5751476, COSM5751871, COSM5752026, COSM5752029,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E668fs*41, p.H649fs*60, p.I62fs*21, p.R724fs*2, p.T901fs*8, p.V1045fs*13, p.V658fs*51, p.Y652fs*57	Complex - frameshift, Insertion - Frameshift	1:64837944-64837944, 1:64839743-64839744, 1:64844834-64844835, 1:64845628-64845628, 1:64846664-64846665, 1:64846682-64846683, 1:64846692-64846692, 1:64883298-64883298,	Info_not_available	Info_not_available	26206799
JAK1	6190	COSM41755,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm, lymphoid_neoplasm	p.R879H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27997762
JAK1	6190	COSM6842521,	haematopoietic_and_lymphoid_tissue	other	p.V310I	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28241173
JAK1	6190	COSM41765, COSM6196692,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N973K, p.Y652H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28410228
JAK1	6190	COSM6904598, COSM6904599,	breast	carcinoma	p.H106Y, p.K795E	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28921573
JAK1	6190	COSM41727, COSM41728,	central_nervous_system, stomach	carcinoma, glioma	p.L698L, p.N719fs*7	Insertion - Frameshift, Substitution - coding silent	Info_not_available	Info_not_available	Info_not_available	Info_not_available
JAK1	6190	COSM6995426,	ovary	germ_cell_tumour	p.R20R	Substitution - coding silent	1:64883422-64883422,	Info_not_available	0.61898	28954785
JAK1	6190	COSM5029115,	breast	carcinoma	p.F1134L	Substitution - Missense	1:64834625-64834625,	Info_not_available	0.61706	22722193
JAK1	6190	COSM3966676, COSM6494362,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D1031D, p.L42L	Substitution - coding silent	1:64837979-64837979, 1:64883356-64883356,	Info_not_available	0.55416, .69495	27534895
JAK1	6190	COSM1343905, COSM1343914, COSM1343915, COSM1560531, COSM1639943, COSM2239148, COSM41842, COSM4693741, COSM6458269, COSM6909956, COSM6912578, COSM6914585, COSM6914586, COSM6919619, COSM6919901, COSM6922237, COSM6924668, COSM6925427, COSM6938769, COSM6949782, COSM6958466, COSM6960148, COSM6962443, COSM6964180, COSM6964205, COSM6966990, COSM6968188, COSM6970337, COSM6971299, COSM6972967, COSM6977414, COSM6981076,	NS, biliary_tract, bone, breast, endometrium, kidney, large_intestine, liver, lung, prostate, skin, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract	carcinoid-endocrine_tumour, carcinoma, chondrosarcoma, gastrointestinal_stromal_tumour, leiomyosarcoma, malignant_melanoma	p.A1006*, p.E1147fs?, p.E83K, p.G673fs*30, p.I943fs*33, p.K142fs*26, p.K345fs*32, p.K616delK, p.K860fs*16, p.L346fs*4, p.L431fs*22, p.L910S, p.N136fs*32, p.N339fs*2, p.N339fs*3, p.N357fs*20, p.P131L, p.P430fs*2, p.P861fs*4, p.Q387fs*66, p.Q644fs*57, p.R104W, p.R343Q, p.R835fs*12, p.S333fs*2, p.S524fs*12, p.T1095I, p.T1100fs*6, p.T868fs*8, p.V36M, p.Y422fs*11, p.Y89S	Complex - frameshift, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Substitution - Missense, Substitution - Nonsense	1:64834565-64834588, 1:64835467-64835467, 1:64835480-64835481, 1:64838055-64838056, 1:64839618-64839618, 1:64839716-64839717, 1:64841293-64841293, 1:64841313-64841314, 1:64841314-64841314, 1:64841503-64841504, 1:64845610-64845610, 1:64846698-64846704, 1:64847582-64847584, 1:64855585-64855586, 1:64860149-64860150, 1:64860150-64860150, 1:64860175-64860176, 1:64864803-64864804, 1:64864898-64864898, 1:64864927-64864928, 1:64864928-64864928, 1:64864935-64864935, 1:64864946-64864947, 1:64864947-64864947, 1:64864964-64864965, 1:64873428-64873428, 1:64873446-64873446, 1:64873461-64873462, 1:64879044-64879045, 1:64879088-64879088, 1:64879107-64879107, 1:64883376-64883376,	Info_not_available	0.55012, .61989, .64445, .68886, Info_not_available	28481359