Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
AKT2	Affinity Capture-Western, Biochemical Activity	physical	12048203	NA	BioGRID
ARRB2	Affinity Capture-MS, Co-localization, anti tag coimmunoprecipitation, proximity ligation assay	association, physical, physical association	17620599, 25241761	0.56	BioGRID, IntAct
ATG16L2	Affinity Capture-Western	physical	23563314	NA	BioGRID
AURKA	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	17939994	0.40	BioGRID, IntAct
BCL10	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex	physical	11113112, 14695475, 22547678	NA	BioGRID
BCL2	Affinity Capture-Western	physical	22262057	NA	BioGRID
BCL3	Biochemical Activity	physical	28689659	NA	BioGRID
BTRC	Biochemical Activity	physical	12504025	NA	BioGRID
CARD11	Affinity Capture-Western, Co-localization	physical	16356855, 18625728	NA	BioGRID
CASP8	Affinity Capture-Western	physical	11002417	NA	BioGRID
CD40	Affinity Capture-MS, Affinity Capture-Western	physical	20614026	NA	BioGRID
CDC37	Affinity Capture-Luminescence, Affinity Capture-MS, Reconstituted Complex, anti tag coimmunoprecipitation, tandem affinity purification	association, physical, physical association	11864612, 14743216, 21903422, 24189400, 25036637	0.74	BioGRID, IntAct
CDC73	Co-fractionation	physical	22863883	NA	BioGRID
CFTR	Affinity Capture-MS	physical	26618866	NA	BioGRID
CHUK	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, protein kinase assay, tandem affinity purification	phosphorylation reaction, physical, physical association	10755617, 11585904, 14743216, 9346485, 9520446, 9721103	0.61	BioGRID, IntAct
CLU	Affinity Capture-Western	physical	20028970	NA	BioGRID
COMMD7	Affinity Capture-Western	physical	26060140	NA	BioGRID
COPS3	Affinity Capture-Western	physical	23636414	NA	BioGRID
COPS5	Affinity Capture-Western, Biochemical Activity	physical	19656241, 23636414	NA	BioGRID
CREBBP	Affinity Capture-Western, Biochemical Activity, Two-hybrid, affinity chromatography technology	association, physical	11971985, 14597638, 17434128	0.35	BioGRID, IntAct
CSNK2A1	Biochemical Activity	physical	9914500	NA	BioGRID
CTNNB1	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex	physical	11527961, 12589056	NA	BioGRID
CUEDC2	Affinity Capture-Western, Two-hybrid	physical	18362886	NA	BioGRID
CUL1	Affinity Capture-Western	physical	17914462	NA	BioGRID
DHX29	Co-fractionation	physical	22939629	NA	BioGRID
DHX40	Co-fractionation	physical	22939629	NA	BioGRID
DUSP1	Affinity Capture-Western	physical	10022904	NA	BioGRID
EGLN3	Affinity Capture-Western	physical	23732909	NA	BioGRID
EIF2AK2	Affinity Capture-Western	physical	10723127, 10848580	NA	BioGRID
ELAVL1	Affinity Capture-Western	physical	23115237	NA	BioGRID
ELP1	Affinity Capture-Western	physical	10094049, 9751059	NA	BioGRID
EP300	Co-localization	physical	19838210	NA	BioGRID
ERBIN	Biochemical Activity	physical	22547678	NA	BioGRID
ERC1	Affinity Capture-Western, Co-purification	physical	15218148	NA	BioGRID
ESR1	Co-localization	physical	15808510	NA	BioGRID
FANCA	Affinity Capture-Western, Two-hybrid	physical	12210728, 14499622	NA	BioGRID
FKBP5	Affinity Capture-Luminescence, Affinity Capture-MS, anti tag coimmunoprecipitation, tandem affinity purification	association, physical, physical association	14743216, 25036637	0.64	BioGRID, IntAct
FOXO3	Affinity Capture-Western, Reconstituted Complex	physical	15084260	NA	BioGRID
GLI1	Affinity Capture-Western	physical	26603838	NA	BioGRID
HIST2H3C	Affinity Capture-Western, Reconstituted Complex	physical	17643371	NA	BioGRID
HNRNPA1	Affinity Capture-Western, Far Western	physical	24720748	NA	BioGRID
HSP90AA1	Affinity Capture-MS, Affinity Capture-Western, tandem affinity purification	association, physical, physical association	14743216, 19875381, 22384180	0.56	BioGRID, IntAct
HSPB1	Affinity Capture-Western	physical	16840786	NA	BioGRID
HTT	Biochemical Activity	physical	20026656	NA	BioGRID
IFIT5	Affinity Capture-Western, Reconstituted Complex	physical	26334375	NA	BioGRID
IKBKB	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-fractionation, Co-localization, Co-purification, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, proximity ligation assay, tandem affinity purification	association, physical, physical association	10733566, 10968790, 11057907, 11080499, 11585904, 11864612, 11971985, 12210728, 12244103, 12486103, 14743216, 16129692, 16286467, 16319058, 17693255, 20434986, 20932476, 21575199, 21784860, 21903422, 25241761, 25748427, 25852190, 28514442, 9346241, 9346484, 9346485, 9721103, 9751060, 9914500	0.94	BioGRID, IntAct, MINT
IKBKE	Biochemical Activity	physical	9914500	NA	BioGRID
IKBKG	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-fractionation, Co-purification, Protein-peptide, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification	association, physical, physical association	10733566, 10980203, 11057907, 11080499, 11485410, 11864612, 11877453, 12138192, 12244103, 12459277, 12486103, 12612076, 14743216, 15184390, 15749833, 16126728, 16319058, 16497931, 16583354, 16611882, 16938294, 17000764, 17244613, 17363973, 17568778, 17728323, 17977820, 18079694, 18207244, 18266467, 18462684, 18949366, 19666608, 19815509, 19959994, 20098747, 20368414, 20434986, 21455180, 21703539, 21903422, 22547678, 22605335, 22990857, 23131831, 23986494, 24469399, 24618592, 25304104, 26496610, 26500060, 27929056, 28249776, 28514442, 9751060	0.96	BioGRID, IntAct, MINT
INSYN2	Affinity Capture-MS	physical	28514442	NA	BioGRID
IRAK1	Affinity Capture-Western	physical	11096118, 18180283	NA	BioGRID
IRF5	Affinity Capture-Western	physical	19786094	NA	BioGRID
IRS1	Affinity Capture-Western	physical	12351658	NA	BioGRID
KEAP1	Affinity Capture-MS, anti tag coimmunoprecipitation	physical, physical association	20600852, 27621311	0.40	BioGRID, IntAct
KLHL21	Affinity Capture-Western	physical	27387502	NA	BioGRID
MAGED1	Affinity Capture-Western	physical	20100315	NA	BioGRID
MAP3K1	Affinity Capture-Western, Biochemical Activity	physical	16286467, 9689078, 9819420	NA	BioGRID
MAP3K11	Biochemical Activity	physical	10713178	NA	BioGRID
MAP3K14	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-localization, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, protein kinase assay, proximity ligation assay, tandem affinity purification	association, phosphorylation reaction, physical, physical association	10094049, 10887201, 11278268, 14743216, 15084608, 15208311, 16286467, 16498412, 17563756, 20348096, 25241761, 28514442, 9244310, 9520446	0.88	BioGRID, IntAct, MINT
MAP3K3	Co-localization, proximity ligation assay, tandem affinity purification	physical, physical association	14743216, 25241761	0.59	BioGRID, IntAct
MAP3K4	Biochemical Activity	physical	22547678	NA	BioGRID
MAP3K7	Affinity Capture-Western, Co-localization, coimmunoprecipitation, proximity ligation assay	association, physical, physical association	10094049, 10187861, 16893890, 20200282, 25241761, 9742107	0.56	BioGRID, IntAct, MINT
MAP3K8	Affinity Capture-Western, Biochemical Activity	physical	10072079	NA	BioGRID
MTOR	Affinity Capture-Western, Co-purification	physical	18490760, 18519641	NA	BioGRID
MYC	Affinity Capture-Western, anti bait coimmunoprecipitation, confocal microscopy	colocalization, physical, physical association	21575199	0.46	BioGRID, IntAct
MYH14	Co-fractionation, tandem affinity purification	physical, physical association	14743216, 22863883	0.40	BioGRID, IntAct
MYL12A	Co-fractionation, tandem affinity purification	physical, physical association	14743216, 22863883	0.40	BioGRID, IntAct
NCOA3	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-localization, Reconstituted Complex, coimmunoprecipitation	physical, physical association	11971985, 15383283, 15808510, 16051665	0.40	BioGRID, IntAct
NCOR1	Biochemical Activity	physical	17630505	NA	BioGRID
NCOR2	Biochemical Activity	physical	15494311, 16382138	NA	BioGRID
NFKB1	Affinity Capture-Western, Biochemical Activity, protein kinase assay, tandem affinity purification	association, phosphorylation reaction, physical	10469655, 11297557, 11976329, 12482991, 25609649	0.71	BioGRID, IntAct, MINT
NFKB2	Affinity Capture-Western, Biochemical Activity, tandem affinity purification	physical, physical association	14743216, 15140882, 16303288, 16651533, 17563756	0.40	BioGRID, IntAct
NFKBIA	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, protein kinase assay, tandem affinity purification	phosphorylation reaction, physical, physical association	10094049, 10733566, 11080499, 11113112, 11940602, 12054687, 12138192, 12190313, 12411322, 12486103, 12624112, 12730857, 14743216, 15310755, 15590691, 15670770, 16219905, 16286467, 16319058, 16354686, 17053167, 17363905, 17379600, 17384642, 18003900, 18074035, 18501560, 18519641, 18922877, 18949366, 19959994, 20133937, 20434986, 20449947, 20932476, 21765415, 23602409, 24270572, 24618592, 26186194, 28514442, 9252186, 9346485, 9520446, 9689078, 9721103, 9751059, 9914500	0.95	BioGRID, IntAct
NFKBIB	Affinity Capture-Western, Biochemical Activity, tandem affinity purification	physical, physical association	11485410, 14743216, 9346485, 9689078	0.40	BioGRID, IntAct
NLRC5	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation	physical, physical association	20434986	0.52	BioGRID, IntAct
NLRP2	Affinity Capture-Western	physical	15456791	NA	BioGRID
NLRP4	Affinity Capture-Western	physical	12093792	NA	BioGRID
NTRK1	Affinity Capture-MS	physical	25921289	NA	BioGRID
PAF1	Co-fractionation	physical	22863883	NA	BioGRID
PAX8	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
PIAS1	Affinity Capture-Western	physical	17540171, 23032264	NA	BioGRID
PPM1B	Affinity Capture-Western, Co-localization, proximity ligation assay	physical, physical association	14585847, 25241761	0.40	BioGRID, IntAct
PPP1CA	Affinity Capture-Western	physical	18949366	NA	BioGRID
PPP2CA	Affinity Capture-Western, molecular sieving	association, physical	16126728	0.35	BioGRID, IntAct, MINT
PRKCA	Affinity Capture-Western, Reconstituted Complex	physical	10022904	NA	BioGRID
PRKCB	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
PRKCD	Affinity Capture-Western, Reconstituted Complex	physical	10022904	NA	BioGRID
PRKCI	Affinity Capture-Western, Reconstituted Complex	physical	10022904	NA	BioGRID
PRKCQ	Affinity Capture-Western	physical	15802604, 17363905, 20164171	NA	BioGRID
PRKDC	Biochemical Activity, Reconstituted Complex	physical	9632806	NA	BioGRID
PSG1	Affinity Capture-MS	physical	28514442	NA	BioGRID
PSMD9	Affinity Capture-Western, Phenotypic Suppression	genetic, physical	24720748	NA	BioGRID
PYCARD	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, confocal microscopy	association, colocalization, physical	12486103	0.51	BioGRID, IntAct
RELA	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification	association, physical, physical association	14743216, 15489227, 16382138, 17434128, 18519641, 21903422, 22689577, 8246997	0.40, 0.56	BioGRID, IntAct
RICTOR	Affinity Capture-Western, Reconstituted Complex	physical	23872070	NA	BioGRID
RIPK1	Co-fractionation	physical	10980203	NA	BioGRID
RIPK2	Biochemical Activity	physical	22547678	NA	BioGRID
RPL27	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
RPTOR	Affinity Capture-Western	physical	18519641	NA	BioGRID
SASH1	Affinity Capture-Western	physical	23776175	NA	BioGRID
SHARPIN	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical	21455180	0.35	BioGRID, IntAct
SHC4	Affinity Capture-MS	physical	28514442	NA	BioGRID
SMAD2	Affinity Capture-Western, anti tag coimmunoprecipitation, pull down	physical, physical association	18268325	0.52	BioGRID, IntAct
SMAD3	Affinity Capture-Western, pull down	physical, physical association	18268325	0.40	BioGRID, IntAct
SMN1	Affinity Capture-Western	physical	28214532	NA	BioGRID
SRC	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical	12707358, 15749833	0.35	BioGRID, IntAct
SRPK1	Biochemical Activity	physical	23602568	NA	BioGRID
SRPK2	Biochemical Activity	physical	23602568	NA	BioGRID
STAP2	Affinity Capture-Western, anti tag coimmunoprecipitation	association, physical	16365431	0.35	BioGRID, IntAct
STUB1	Affinity Capture-Western	physical	23322406	NA	BioGRID
TAB2	Affinity Capture-Western	physical	15836773	NA	BioGRID
TANK	Affinity Capture-Western	physical	12133833	NA	BioGRID
TNF	Affinity Capture-MS, Phenotypic Suppression	genetic, physical	20005846, 24720748	NA	BioGRID
TNFAIP3	Affinity Capture-Western	physical	11594795	NA	BioGRID
TNFRSF1A	Affinity Capture-Western, Biochemical Activity	physical	18949366, 21724995	NA	BioGRID
TNFRSF1B	Affinity Capture-Western	physical	19287455	NA	BioGRID
TNIP2	Affinity Capture-Western, Biochemical Activity	physical	21784860	NA	BioGRID
TP53	Affinity Capture-Western	physical	17434128	NA	BioGRID
TP63	Affinity Capture-Western	physical	20145131	NA	BioGRID
TP73	Affinity Capture-Western, Reconstituted Complex	physical	17452332, 21482671	NA	BioGRID
TPX2	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	17939994	0.40	BioGRID, IntAct
TRADD	Co-fractionation	physical	10980203	NA	BioGRID
TRAF1	Affinity Capture-Western	physical	12709429, 19287455	NA	BioGRID
TRAF2	Affinity Capture-Western, Co-localization, Reconstituted Complex, proximity ligation assay	physical, physical association	11359906, 19150425, 20449947, 23007157, 25241761, 9244310	0.40	BioGRID, IntAct
TRAF3IP2	Affinity Capture-Western, Co-fractionation	physical	10962033, 12943667	NA	BioGRID
TRAF4	Biochemical Activity	physical	22547678	NA	BioGRID
TRAF6	Affinity Capture-Western	physical	15836773	NA	BioGRID
TRIM22	Affinity Capture-Western	physical	25510414	NA	BioGRID
TRIM27	Affinity Capture-Western, Biochemical Activity	physical	16393995	NA	BioGRID
TRIM40	Affinity Capture-Western	physical	21474709	NA	BioGRID
TRPC4AP	Affinity Capture-Western	physical	14585990	NA	BioGRID
UBC	Reconstituted Complex	physical	28190767	NA	BioGRID
UBE2I	Biochemical Activity	physical	11853669	NA	BioGRID
UBE2N	Biochemical Activity	physical	11057907	NA	BioGRID
USP18	Affinity Capture-Western	physical	26240016	NA	BioGRID
XPO1	Affinity Capture-MS	physical	26673895	NA	BioGRID