Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
APAF1	Affinity Capture-Western, Co-fractionation, Reconstituted Complex, coimmunoprecipitation, cosedimentation, cosedimentation in solution, cosedimentation through density gradient, electron microscopy, molecular sieving, protease accessibility laddering, protease assay, pull down, x-ray crystallography	association, cleavage reaction, direct interaction, physical, physical association	10206961, 10376594, 11113115, 11242052, 15262985, 19494828, 19698783, 20462491, 20829884, 21827945, 27197231, 27476169, 9390557, 9488720, 9539746, 9922454	0.96	BioGRID, IntAct, MINT
ARNT	Biochemical Activity, Reconstituted Complex	physical	11593383	NA	BioGRID
BAX	Co-fractionation	physical	15254227	NA	BioGRID
BCL2L1	Affinity Capture-Western, Co-localization, proximity ligation assay	physical, physical association	25241761, 9539746	0.40	BioGRID, IntAct
BIRC2	Affinity Capture-Western, Co-crystal Structure, Co-localization, Protein-peptide, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, proximity ligation assay, surface plasmon resonance, two hybrid array, two hybrid prey pooling approach, validated two hybrid, x-ray crystallography	direct interaction, physical, physical association	11084335, 15069192, 16339151, 16701639, 19153467, 25241761, 25416956, 27197231, 9545235, 	0.88	BioGRID, IntAct
BIRC3	Affinity Capture-Western, Co-localization, Reconstituted Complex, Two-hybrid, proximity ligation assay, two hybrid	physical, physical association	15069192, 16339151, 16701639, 21988832, 25241761, 9545235	0.57	BioGRID, IntAct
BIRC5	Affinity Capture-Western, Co-localization, coimmunoprecipitation, proximity ligation assay	physical, physical association	11024045, 11069302, 25241761	0.59	BioGRID, IntAct, MINT
BIRC6	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex	physical	15200957, 15300255, 15507451	NA	BioGRID
BIRC7	Affinity Capture-Western, Two-hybrid, anti tag coimmunoprecipitation, coimmunoprecipitation, fluorescence polarization spectroscopy, pull down, two hybrid array, two hybrid prey pooling approach, validated two hybrid	physical, physical association	11024045, 11084335, 11801603, 25416956, 	0.89	BioGRID, IntAct, MINT
BIRC8	Affinity Capture-MS, Reconstituted Complex, Two-hybrid	physical	11390657, 25416956, 28514442	NA	BioGRID
BRCA1	Affinity Capture-Western	physical	16322207	NA	BioGRID
CASP10	Biochemical Activity	physical	8962078	NA	BioGRID
CASP12	Biochemical Activity	physical	12097332	NA	BioGRID
CASP2	Phenotypic Suppression	genetic	11832478	NA	BioGRID
CASP3	Biochemical Activity, Co-localization, experimental interaction detection, protease assay, proximity ligation assay	association, cleavage reaction, direct interaction, physical, physical association	11230124, 11242052, 15507451, 15941357, 17437405, 18723680, 25241761	0.44, 0.67	BioGRID, IntAct, MINT
CASP7	Biochemical Activity, protease assay	cleavage reaction, physical	18723680	0.44	BioGRID, IntAct
CASP8	Biochemical Activity, Phenotypic Suppression	genetic, physical	11832478, 8962078	NA	BioGRID
CRYAB	Affinity Capture-Western	physical	23074197	NA	BioGRID
CYCS	Co-localization, proximity ligation assay	physical, physical association	25241761	0.40	BioGRID, IntAct
DCC	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	11248093, 16537496, 19721007	0.59	BioGRID, IntAct
HSD17B4	Two-hybrid, two hybrid	physical, physical association	21988832	0.37	BioGRID, IntAct
JUN	Biochemical Activity	physical	23678002	NA	BioGRID
MAPK1	Biochemical Activity	physical	12792650	NA	BioGRID
MSTO1	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
NAIP	Far Western	physical	15280366	NA	BioGRID
NLRP1	Affinity Capture-Western	physical	11076957, 11113115	NA	BioGRID
NOD1	Affinity Capture-Western, coimmunoprecipitation	physical, physical association	10329646	0.40	BioGRID, IntAct, MINT
PTCH1	Affinity Capture-Western	physical	25092867	NA	BioGRID
RB1	Biochemical Activity	physical	15735701	NA	BioGRID
RNF2	Biochemical Activity	physical	17379327	NA	BioGRID
RNF34	Affinity Capture-Western	physical	15069192	NA	BioGRID
SQSTM1	Affinity Capture-Western	physical	24121507	NA	BioGRID
VCP	Affinity Capture-Western	physical	23383273	NA	BioGRID
XIAP	Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Co-localization, Far Western, Protein-peptide, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, barcode fusion genetics two hybrid, experimental interaction detection, fluorescence polarization spectroscopy, proximity ligation assay, pull down, two hybrid array, two hybrid pooling approach, two hybrid prey pooling approach, validated two hybrid, x-ray crystallography	association, direct interaction, physical, physical association	11242052, 11390657, 11801603, 12620238, 14512414, 14523016, 15069192, 15280366, 15300255, 15507451, 15749826, 16189514, 16322207, 16701639, 17179183, 17291493, 18022362, 19153467, 19698783, 23074197, 25241761, 25416956, 27107012, 9545235, 	0.96	BioGRID, IntAct, MINT