Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
SPRY2	11270	COSM5610695,	skin	malignant_melanoma	p.R72C	Substitution - Missense	13:80337492-80337492,	PATHOGENIC	0.98516	26343386
SPRY2	11270	COSM95276,	lung	carcinoma	p.C218R	Substitution - Missense	13:80337054-80337054,	PATHOGENIC	0.96924	20668451
SPRY2	11270	COSM5610693,	skin	malignant_melanoma	p.S260S	Substitution - coding silent	13:80336926-80336926,	PATHOGENIC	0.77802	26343386
SPRY2	11270	COSM5610694,	skin	malignant_melanoma	p.P289P	Substitution - coding silent	13:80336839-80336839,	NEUTRAL	0.20537	26343386
SPRY2	11270	COSM5611392,	skin	malignant_melanoma	p.R123K	Substitution - Missense	13:80337337-80337338,	Info_not_available	Info_not_available	26343386