Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ACOX1 anti tag coimmunoprecipitation association 26496610 0.35 IntAct AKT1 Affinity Capture-Western, Biochemical Activity, proximity ligation assay, pull down physical, physical association 10576742, 19058874, 19197339, 25241761 0.59 BioGRID, IntAct, MINT AMER1 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct ARAF anti bait coimmunoprecipitation association 20130576 0.35 IntAct BAD Biochemical Activity, Co-localization, proximity ligation assay physical, physical association 15849194, 19667065, 23397142, 25241761 0.59 BioGRID, IntAct BAG1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, two hybrid physical, physical association 11231577, 8692945 0.51 BioGRID, IntAct, MINT BAG2 luminescence based mammalian interactome mapping physical association 25036637 0.40 IntAct BCL2L1 Co-localization, Reconstituted Complex, proximity ligation assay physical, physical association 25241761, 8929532 0.40 BioGRID, IntAct BRAF Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, solid phase assay association, direct interaction, physical, physical association 11325826, 18332145, 20130576, 20141835, 20212043, 22169110, 22510884, 23153539, 23680146, 23934108, 25155755, 26466569, 28514442 0.96 BioGRID, IntAct, MINT CACYBP luminescence based mammalian interactome mapping physical association 25036637 0.40 IntAct CALU Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25852190, 26496610 0.53 BioGRID, IntAct CASZ1 Two-hybrid, two hybrid array physical, physical association 25640309 0.37 BioGRID, IntAct, MINT CCT3 Two-hybrid, two hybrid physical, physical association 12620389 0.37 BioGRID, IntAct CCT8 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25852190 0.35 BioGRID, IntAct CDC25A Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation physical, physical association 7644510, 7744247, 9230211 0.40 BioGRID, IntAct CDC37 Affinity Capture-Luminescence, Affinity Capture-MS, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping, tandem affinity purification association, physical, physical association 17979178, 24189400, 25036637 0.71 BioGRID, IntAct CFLAR Affinity Capture-Western, Two-hybrid, two hybrid array physical, physical association 10837247, 16537561, 21988832 0.37 BioGRID, IntAct COPS3 two hybrid physical association 12620389 0.37 IntAct COPS5 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct CPS1 two hybrid physical association 12620389 0.37 IntAct CRKL proximity ligation assay physical association 23397142 0.40 IntAct DNAJA1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25852190 0.35 BioGRID, IntAct DYNLL1 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct DYNLL2 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct EEF1E1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct EFEMP1 two hybrid physical association 12620389 0.37 IntAct EGFR PCA, Two-hybrid, ubiquitin reconstruction physical, physical association 24658140, 25402006 0.37 BioGRID, IntAct EMD Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25852190 0.35 BioGRID, IntAct FKBPL luminescence based mammalian interactome mapping physical association 25036637 0.40 IntAct HRAS Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, confocal microscopy, fluorescent resonance energy transfer, molecular sieving, pull down, two hybrid, x-ray crystallography colocalization, direct interaction, physical, physical association 10369681, 10783161, 10882715, 10887184, 10922060, 12379659, 12620389, 14654780, 14724584, 15031288, 15664191, 15688026, 16803888, 18073111, 18273062, 19063885, 19222999, 19696784, 20080631, 20133694, 20178605, 22169110, 24929361, 25684575, 26721396, 7862125, 7969158, 8332187, 8332195, 8530446, 8628317, 8670882, 9144171, 9150145, 9154803, 9523700 0.97 BioGRID, IntAct, MINT HSP90AA1 Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, luminescence based mammalian interactome mapping physical, physical association 15618521, 16093354, 16330544, 16504566, 17409432, 17699868, 19011619, 20039095, 20159553, 22939624, 23118896, 24462205, 25036637, 27703006, 8408024, 8962087 0.40 BioGRID, IntAct HSP90AB1 anti bait coimmunoprecipitation, luminescence based mammalian interactome mapping, tandem affinity purification association, physical association 16330544, 17979178, 22939624 0.69 IntAct HSPA5 anti bait coimmunoprecipitation, cosedimentation, pull down colocalization, physical association 18064632 0.58 IntAct ILK Affinity Capture-MS, anti tag coimmunoprecipitation, tandem affinity purification association, physical 23455922, 25852190, 26496610 0.64 BioGRID, IntAct INTS10 two hybrid physical association 12620389 0.37 IntAct IQCB1 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct IRS4 Affinity Capture-Luminescence, Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25036637 0.35 BioGRID, IntAct KRAS Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Synthetic Lethality, Two-hybrid, anti tag coimmunoprecipitation, fluorescent resonance energy transfer, pull down association, direct interaction, genetic, physical, physical association 10783161, 10882715, 10958680, 15192046, 16041367, 16093354, 19029954, 20080631, 20802526, 23153539, 25852190, 26627737, 26721396, 28162770 0.35, 0.68 BioGRID, IntAct KRT18 coimmunoprecipitation, experimental interaction detection phosphorylation reaction, physical association 15314064 0.49 IntAct, MINT KRT19 coimmunoprecipitation physical association 15314064 0.40 IntAct, MINT KRT8 experimental interaction detection association 15314064 0.22 IntAct, MINT KSR1 Biochemical Activity, anti bait coimmunoprecipitation physical, physical association 11741534, 24929361 0.40 BioGRID, IntAct LAS1L Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct MAD2L1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct MAP2K1 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, surface plasmon resonance, tandem affinity purification association, direct interaction, physical, physical association 10757792, 10958680, 15485920, 15866172, 16093354, 17724343, 17979178, 18556463, 19058874, 19197339, 20212043, 21336309, 23934108, 24746704, 25155755, 26496610, 27703006, 9311917 0.44, 0.95 BioGRID, IntAct, MINT MAP2K2 Affinity Capture-Western, Two-hybrid, anti tag coimmunoprecipitation, two hybrid association, physical, physical association 11909642, 16364241, 19058874, 21988832, 24746704, 9808624 0.67 BioGRID, IntAct MAPK6 anti tag coimmunoprecipitation association 26972000 0.35 IntAct MAPK8 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct MLF1 luminescence based mammalian interactome mapping physical association 25036637 0.40 IntAct MRAS Affinity Capture-Western, Reconstituted Complex, fluorescent resonance energy transfer direct interaction, physical 10498616, 20080631, 25022756 0.44 BioGRID, IntAct MRC2 Two-hybrid, two hybrid array physical, physical association 25640309 0.37 BioGRID, IntAct, MINT MSH2 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct MYC Affinity Capture-MS, Reconstituted Complex, tandem affinity purification association, physical 17314511, 9315742 0.35 BioGRID, IntAct NCAPG2 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct NFATC3 anti bait coimmunoprecipitation physical association 24330068 0.40 IntAct, MINT NPHP4 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct NRAS Affinity Capture-Western, Synthetic Lethality, anti tag coimmunoprecipitation, fluorescent resonance energy transfer, pull down, two hybrid array, two hybrid prey pooling approach direct interaction, genetic, physical, physical association 10882715, 18641128, 20080631, 21478863, 28162770, 0.80 BioGRID, IntAct NUDCD3 luminescence based mammalian interactome mapping physical association 25036637 0.40 IntAct NUDT14 two hybrid physical association 12620389 0.37 IntAct NUP107 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct NUP133 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct NUP160 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct OIP5 two hybrid physical association 12620389 0.37 IntAct PAK1 protein kinase assay phosphorylation reaction 17097642 0.44 IntAct, MINT PAK2 nuclear magnetic resonance, protein kinase assay direct interaction, phosphorylation reaction 16837009 0.56 IntAct PAQR3 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical association 17724343 0.58 IntAct PBK two hybrid physical association 12620389 0.37 IntAct PCDH7 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct PDGFRB Reconstituted Complex, proximity ligation assay physical, physical association 23397142, 2475255 0.40 BioGRID, IntAct PDLIM2 Two-hybrid, two hybrid array physical, physical association 25640309 0.37 BioGRID, IntAct, MINT PEBP1 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, peptide array, pull down, surface plasmon resonance association, direct interaction, physical, physical association 10757792, 14654844, 17097642, 21831839 0.76 BioGRID, IntAct, MINT PEBP4 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down association, physical, physical association 15302887, 19197339 0.60 BioGRID, IntAct, MINT PHB Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation physical, physical association 10523633, 16041367, 24568222 0.40 BioGRID, IntAct PIN1 Affinity Capture-Western, anti tag coimmunoprecipitation association, physical, physical association 15664191, 20179103, 20179161 0.56 BioGRID, IntAct PKM Two-hybrid, two hybrid physical, physical association 12620389 0.37 BioGRID, IntAct PPP2CA Affinity Capture-Western, anti tag coimmunoprecipitation, phosphatase assay dephosphorylation reaction, physical, physical association 16041367, 16239230 0.54 BioGRID, IntAct, MINT PPP2CB Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct PPP2R5C anti tag coimmunoprecipitation, phosphatase assay dephosphorylation reaction, physical association 16239230 0.54 IntAct, MINT PSMD2 luminescence based mammalian interactome mapping physical association 25036637 0.40 IntAct RAF1 Affinity Capture-Western, anti tag coimmunoprecipitation, tandem affinity purification, x-ray crystallography association, direct interaction, physical, physical association 16093354, 17979178, 20130576, 22169110, 22510884, 27703006 0.81 BioGRID, IntAct, MINT RALGDS pull down association 19075231 0.35 IntAct RAP1A Co-crystal Structure, Reconstituted Complex, Two-hybrid, x-ray crystallography direct interaction, physical 10454553, 7791872, 7862125, 8756332, 9867809 0.62 BioGRID, IntAct RB1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation physical, physical association 10523633, 15485920, 19058874, 21139044, 9819434 0.40 BioGRID, IntAct RBBP8 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct RCAN1 pull down physical association 15935327 0.40 IntAct RHEB Affinity Capture-Western, Reconstituted Complex, Two-hybrid, pull down direct interaction, physical 15150271, 15854902, 19222999, 9001246 0.44 BioGRID, IntAct, MINT RIPK4 anti tag coimmunoprecipitation association 26972000 0.35 IntAct RPGRIP1L Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct RRAS2 Reconstituted Complex, Two-hybrid, two hybrid physical, physical association 10557073, 10783161, 12620389 0.37 BioGRID, IntAct SFN Affinity Capture-MS, Affinity Capture-Western, FRET, anti tag coimmunoprecipitation, biochemical, tandem affinity purification association, physical, physical association 11697890, 15778465, 16041367, 16093354, 25852190, 26578655 0.67 BioGRID, IntAct, MINT SPATA7 Affinity Capture-MS, inference by socio-affinity scoring, tandem affinity purification association, physical, physical association 27173435, 0.27, 0.35 BioGRID, IntAct SS18L2 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct STIP1 luminescence based mammalian interactome mapping physical association 25036637 0.40 IntAct STK3 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, peptide array, pull down direct interaction, physical, physical association 15618521, 17889669, 20086174, 20212043, 24929361 0.65 BioGRID, IntAct STUB1 luminescence based mammalian interactome mapping physical association 25036637 0.40 IntAct SYNPO Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct TIMM50 Affinity Capture-MS, anti tag coimmunoprecipitation, two hybrid association, physical, physical association 12620389, 25852190 0.55 BioGRID, IntAct TMEM63B Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct XIAP Affinity Capture-Western, Biochemical Activity, Co-localization, Reconstituted Complex, Two-hybrid, proximity ligation assay physical, physical association 16964381, 19011619, 25241761 0.40 BioGRID, IntAct YWHAB Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, biochemical, two hybrid association, physical, physical association 10620507, 10848612, 11697890, 12360521, 12620389, 16041367, 16093354, 19595761, 24255178, 25852190, 7644510, 7882972, 7935795, 8085158, 8702721 0.93 BioGRID, IntAct, MINT YWHAE Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, anti tag coimmunoprecipitation, biochemical, two hybrid association, physical, physical association 11697890, 16041367, 16093354, 17979178, 19608861, 25852190, 7644510, 8702721 0.66 BioGRID, IntAct, MINT YWHAG Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, biochemical association, physical, physical association 10433554, 10620507, 11697890, 16041367, 16093354, 17353931, 25852190 0.67 BioGRID, IntAct, MINT YWHAH Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, biochemical, tandem affinity purification association, physical, physical association 10620507, 11697890, 11969417, 16041367, 16093354, 17979178, 25852190, 26496610, 8702721 0.77 BioGRID, IntAct, MINT YWHAQ Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, biochemical, pull down association, physical, physical association 10620507, 10757792, 11697890, 15618521, 16041367, 16093354, 17353931, 25852190, 7479742, 7760835, 8663231 0.74 BioGRID, IntAct, MINT YWHAZ Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, biochemical, coimmunoprecipitation, lex-a dimerization assay, peptide array, pull down, surface plasmon resonance, tandem affinity purification, two hybrid, x-ray crystallography association, direct interaction, physical, physical association 10611249, 10620507, 10887173, 11697890, 12861023, 14688280, 15664191, 16041367, 16093354, 16306228, 17979178, 19049963, 20052757, 20679480, 22222486, 25852190, 7628630, 7935795, 7939632, 8085158, 8601312, 9153224, 9261098, 9632690 0.95 BioGRID, IntAct, MINT YY1 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct