Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PTPN22	9652	COSM5046779,	oesophagus	carcinoma	p.E50Q	Substitution - Missense	1:113859400-113859400,	PATHOGENIC	0.91984	24686850
PTPN22	9652	COSM30530,	kidney	carcinoma	p.R70P	Substitution - Missense	1:113859066-113859066,	PATHOGENIC	0.90212	20054297
PTPN22	9652	COSM5025339,	breast	carcinoma	p.L261F	Substitution - Missense	1:113852072-113852072,	PATHOGENIC	0.85917	22722193
PTPN22	9652	COSM26619,	kidney	renal_cell_carcinoma	p.R690H	Substitution - Missense	1:113830014-113830014,	NEUTRAL	0.1834	20054297
PTPN22	9652	COSM2120396,	oesophagus	carcinoma	p.F469L	Substitution - Missense	1:113837993-113837993,	NEUTRAL	0.03311	24686850