* We recommend a score >= 0.08 for meaningful Gene-Disease associations

GeneID	Gene_Symbol	DisGeNet_diseaseID	Disease_name	DisGeNet score	DisGeNet_sourceDB
5295	PIK3R1	C0878684	SHORT syndrome	0.401098907136852	BEFREE;ORPHANET;UNIPROT
5295	PIK3R1	C0021655	Insulin Resistance	0.202407028523288	CTD_human;GAD
5295	PIK3R1	C0023787	Lipodystrophy	0.200824180352639	BEFREE;HPO
5295	PIK3R1	C0265341	Rieger syndrome	0.200549453568426	BEFREE;HPO
5295	PIK3R1	C1280433	Lipoatrophy	0.200549453568426	BEFREE;HPO
5295	PIK3R1	C0086438	Hypogammaglobulinemia	0.200274726784213	BEFREE;HPO
5295	PIK3R1	C0001768	Agammaglobulinemia	0.200274726784213	BEFREE;HPO
5295	PIK3R1	C0001973	Alcoholic Intoxication, Chronic	0.200274726784213	BEFREE;PSYGENET
5295	PIK3R1	C0015230	Exanthema	0.200274726784213	BEFREE;HPO
5295	PIK3R1	C0020456	Hyperglycemia	0.200274726784213	BEFREE;HPO
5295	PIK3R1	C0021051	Immunologic Deficiency Syndromes	0.200274726784213	BEFREE;HPO
5295	PIK3R1	C0037199	Sinusitis	0.2	HPO
5295	PIK3R1	C0037301	Skin Wrinkling	0.2	HPO
5295	PIK3R1	C0086437	Joint laxity	0.2	HPO
5295	PIK3R1	C0086543	Cataract	0.2	HPO
5295	PIK3R1	C0152421	Macrotia	0.2	HPO
5295	PIK3R1	C0221354	Frontal bossing	0.2	HPO
5295	PIK3R1	C0231246	Failure to gain weight	0.2	HPO
5295	PIK3R1	C0233715	Speech impairment	0.2	HPO
5295	PIK3R1	C0235991	Small for gestational age (disorder)	0.2	HPO
5295	PIK3R1	C0239174	Late tooth eruption	0.2	HPO
5295	PIK3R1	C0240295	Mandibular hypoplasia	0.2	HPO
5295	PIK3R1	C0241210	Speech Delay	0.2	HPO
5295	PIK3R1	C0265610	Congenital clinodactyly	0.2	HPO
5295	PIK3R1	C0271441	Chronic otitis media	0.2	HPO
5295	PIK3R1	C0271650	Impaired glucose tolerance	0.2	HPO
5295	PIK3R1	C0344530	Congenital keratoglobus	0.2	HPO
5295	PIK3R1	C0423113	Telecanthus	0.2	HPO
5295	PIK3R1	C0423224	Sunken eyes	0.2	HPO
5295	PIK3R1	C0423757	Thin skin	0.2	HPO
5295	PIK3R1	C0454644	Delayed speech and language development	0.2	HPO
5295	PIK3R1	C0541764	Delayed bone age	0.2	HPO
5295	PIK3R1	C0554972	Large auricle	0.2	HPO
5295	PIK3R1	C0743359	ear infection chronic	0.2	HPO
5295	PIK3R1	C0853697	Neutrophil count decreased	0.2	HPO
5295	PIK3R1	C0854110	Insulin resistant diabetes	0.2	HPO
5295	PIK3R1	C1167712	Corneal diameter increased	0.2	HPO
5295	PIK3R1	C1386048	Intrauterine retardation	0.2	HPO
5295	PIK3R1	C1510497	Lens Opacities	0.2	HPO
5295	PIK3R1	C1833328	Enlarged epiphyses	0.2	HPO
5295	PIK3R1	C1834055	Thin hypoplastic alae nasi	0.2	HPO
5295	PIK3R1	C1835581	Large protruding ears	0.2	HPO
5295	PIK3R1	C1835884	Triangular face	0.2	HPO
5295	PIK3R1	C1836189	Radially deviated fingers	0.2	HPO
5295	PIK3R1	C1837260	Prominent forehead	0.2	HPO
5295	PIK3R1	C1839764	Broad flat nasal bridge	0.2	HPO
5295	PIK3R1	C1844383	Recurrent bacterial infection	0.2	HPO
5295	PIK3R1	C1848570	Large, floppy ears	0.2	HPO
5295	PIK3R1	C1848924	Infantile onset	0.2	HPO
5295	PIK3R1	C1849227	CLEFT CHIN	0.2	HPO
5295	PIK3R1	C1849367	Nasal bridge wide	0.2	HPO
5295	PIK3R1	C1850189	Large pinnae	0.2	HPO
5295	PIK3R1	C1853193	Recurrent skin infections	0.2	HPO
5295	PIK3R1	C1855062	Large dysplastic ears	0.2	HPO
5295	PIK3R1	C1855650	Birth length less than 3rd percentile	0.2	HPO
5295	PIK3R1	C1857130	Hypoplastic mandible condyle	0.2	HPO
5295	PIK3R1	C1860838	Large prominent ears	0.2	HPO
5295	PIK3R1	C1864156	Conjunctivitis, recurrent	0.2	HPO
5295	PIK3R1	C1867446	Bulging forehead	0.2	HPO
5295	PIK3R1	C2242472	Infection of bone	0.2	HPO
5295	PIK3R1	C2315100	Pediatric failure to thrive	0.2	HPO
5295	PIK3R1	C2748958	Increased susceptibility to bacterial infections	0.2	HPO
5295	PIK3R1	C3152144	AGAMMAGLOBULINEMIA 1, AUTOSOMAL RECESSIVE	0.2	ORPHANET
5295	PIK3R1	C3714976	ACTIVATED PI3K-DELTA SYNDROME	0.2	ORPHANET
5295	PIK3R1	C3806482	Recurrent respiratory infections	0.2	HPO
5295	PIK3R1	C4020846	Prone to bacterial infection	0.2	HPO
5295	PIK3R1	C4020899	Autosomal recessive predisposition	0.2	HPO
5295	PIK3R1	C4021753	Abnormality of the immune system	0.2	HPO
5295	PIK3R1	C4048270	Decreased antibody level in blood	0.2	HPO
5295	PIK3R1	C4280304	Curvature of digit	0.2	HPO
5295	PIK3R1	C4280613	Angle class 3 malocclusion	0.2	HPO
5295	PIK3R1	C4280614	Angle class 2 malocclusion	0.2	HPO
5295	PIK3R1	C0003864	Arthritis	0.2	HPO
5295	PIK3R1	C0006413	Burkitt Lymphoma	0.2	CTD_human
5295	PIK3R1	C0009763	Conjunctivitis	0.2	HPO
5295	PIK3R1	C0010200	Coughing	0.2	HPO
5295	PIK3R1	C0011991	Diarrhea	0.2	HPO
5295	PIK3R1	C0014306	Enophthalmos	0.2	HPO
5295	PIK3R1	C0015672	Fatigue	0.2	HPO
5295	PIK3R1	C0015934	Fetal Growth Retardation	0.2	HPO
5295	PIK3R1	C0015967	Fever	0.2	HPO
5295	PIK3R1	C0017601	Glaucoma	0.2	HPO
5295	PIK3R1	C0018784	Sensorineural Hearing Loss (disorder)	0.2	HPO
5295	PIK3R1	C0019294	Hernia, Inguinal	0.2	HPO
5295	PIK3R1	C0020608	Hypodontia	0.2	HPO
5295	PIK3R1	C0021296	Infant, Small for Gestational Age	0.2	HPO
5295	PIK3R1	C0023012	Language Delay	0.2	HPO
5295	PIK3R1	C0024032	Low Birth Weights	0.2	HPO
5295	PIK3R1	C0024636	Malocclusion	0.2	HPO
5295	PIK3R1	C0024667	Animal Mammary Neoplasms	0.2	CTD_human
5295	PIK3R1	C0024668	Mammary Neoplasms, Experimental	0.2	CTD_human
5295	PIK3R1	C0025990	Micrognathism	0.2	HPO
5295	PIK3R1	C0027092	Myopia	0.2	HPO
5295	PIK3R1	C0029443	Osteomyelitis	0.2	HPO
5295	PIK3R1	C0030469	Paranasal Sinus Diseases	0.2	HPO
5295	PIK3R1	C0221026	X-linked agammaglobulinemia	0.0802747267842131	BEFREE;MGD
5295	PIK3R1	C1458155	Mammary Neoplasms	0.010931649859255	LHGDN
5295	PIK3R1	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	0.0077705391382902	BEFREE;GAD
5295	PIK3R1	C0033578	Prostatic Neoplasms	0.0057405517138406	BEFREE;LHGDN
5295	PIK3R1	C0017636	Glioblastoma	0.00383181960166615	BEFREE;LHGDN
5295	PIK3R1	C2239176	Liver carcinoma	0.00328236603323995	BEFREE;LHGDN
5295	PIK3R1	C0032460	Polycystic Ovary Syndrome	0.0029564820917142	BEFREE;GAD
5295	PIK3R1	C0376358	Malignant neoplasm of prostate	0.0029564820917142	BEFREE;GAD
5295	PIK3R1	C0019693	HIV Infections	0.0026817553075011	BEFREE;GAD
5295	PIK3R1	C0040336	Tobacco Use Disorder	0.002407028523288	GAD
5295	PIK3R1	C0002395	Alzheimer's Disease	0.002407028523288	GAD
5295	PIK3R1	C0009375	Colonic Neoplasms	0.002407028523288	GAD
5295	PIK3R1	C0020538	Hypertensive disease	0.002407028523288	GAD
5295	PIK3R1	C0022661	Kidney Failure, Chronic	0.002407028523288	GAD
5295	PIK3R1	C0028754	Obesity	0.002407028523288	GAD
5295	PIK3R1	C0030297	Pancreatic Neoplasm	0.002407028523288	GAD
5295	PIK3R1	C0031099	Periodontitis	0.002407028523288	GAD
5295	PIK3R1	C0678222	Breast Carcinoma	0.0010989071368524	BEFREE
5295	PIK3R1	C0699790	Colon Carcinoma	0.0010989071368524	BEFREE
5295	PIK3R1	C0027627	Neoplasm Metastasis	0.0010989071368524	BEFREE
5295	PIK3R1	C0476089	Endometrial Carcinoma	0.0008241803526393	BEFREE
5295	PIK3R1	C1883486	Uterine Corpus Cancer	0.0008241803526393	BEFREE
5295	PIK3R1	C0006142	Malignant neoplasm of breast	0.0008241803526393	BEFREE
5295	PIK3R1	C0007102	Malignant tumor of colon	0.0008241803526393	BEFREE
5295	PIK3R1	C0007103	Malignant neoplasm of endometrium	0.0008241803526393	BEFREE
5295	PIK3R1	C0600139	Prostate carcinoma	0.0005494535684262	BEFREE
5295	PIK3R1	C1851841	ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1	0.0005494535684262	BEFREE
5295	PIK3R1	C3495489	Rieger eye malformation sequence	0.0005494535684262	BEFREE
5295	PIK3R1	C0007131	Non-Small Cell Lung Carcinoma	0.0005494535684262	BEFREE
5295	PIK3R1	C0009319	Colitis	0.0005494535684262	BEFREE
5295	PIK3R1	C0023418	leukemia	0.0005494535684262	BEFREE
5295	PIK3R1	C0032461	Polycythemia	0.0002747267842131	BEFREE
5295	PIK3R1	C0038454	Cerebrovascular accident	0.0002747267842131	BEFREE
5295	PIK3R1	C0079731	B-Cell Lymphomas	0.0002747267842131	BEFREE
5295	PIK3R1	C0085110	Severe Combined Immunodeficiency	0.0002747267842131	BEFREE
5295	PIK3R1	C0149678	Epstein-Barr Virus Infections	0.0002747267842131	BEFREE
5295	PIK3R1	C0152264	Familial erythrocytosis	0.0002747267842131	BEFREE
5295	PIK3R1	C0220989	Acquired partial lipodystrophy	0.0002747267842131	BEFREE
5295	PIK3R1	C0242379	Malignant neoplasm of lung	0.0002747267842131	BEFREE
5295	PIK3R1	C0279626	Squamous cell carcinoma of esophagus	0.0002747267842131	BEFREE
5295	PIK3R1	C0342335	Insulin resistance in diabetes	0.0002747267842131	BEFREE
5295	PIK3R1	C0345904	Malignant neoplasm of liver	0.0002747267842131	BEFREE
5295	PIK3R1	C0349639	Juvenile Myelomonocytic Leukemia	0.0002747267842131	BEFREE
5295	PIK3R1	C0494463	Alzheimer Disease, Late Onset	0.0002747267842131	BEFREE
5295	PIK3R1	C0524620	Metabolic Syndrome X	0.0002747267842131	BEFREE
5295	PIK3R1	C0525045	Mood Disorders	0.0002747267842131	BEFREE
5295	PIK3R1	C0555198	Malignant Glioma	0.0002747267842131	BEFREE
5295	PIK3R1	C0596263	Carcinogenesis	0.0002747267842131	BEFREE
5295	PIK3R1	C0677936	Refractory cancer	0.0002747267842131	BEFREE
5295	PIK3R1	C0684249	Carcinoma of lung	0.0002747267842131	BEFREE
5295	PIK3R1	C0699885	Carcinoma of bladder	0.0002747267842131	BEFREE
5295	PIK3R1	C0700095	Central neuroblastoma	0.0002747267842131	BEFREE
5295	PIK3R1	C0740457	Malignant neoplasm of kidney	0.0002747267842131	BEFREE
5295	PIK3R1	C0919267	ovarian neoplasm	0.0002747267842131	BEFREE
5295	PIK3R1	C1306460	Primary malignant neoplasm of lung	0.0002747267842131	BEFREE
5295	PIK3R1	C1335302	Pancreatic Ductal Adenocarcinoma	0.0002747267842131	BEFREE
5295	PIK3R1	C1378703	Renal carcinoma	0.0002747267842131	BEFREE
5295	PIK3R1	C1621958	Glioblastoma Multiforme	0.0002747267842131	BEFREE
5295	PIK3R1	C2145472	Urothelial Carcinoma	0.0002747267842131	BEFREE
5295	PIK3R1	C3241937	Nonalcoholic Steatohepatitis	0.0002747267842131	BEFREE
5295	PIK3R1	C0001956	alcohol use disorder	0.0002747267842131	BEFREE
5295	PIK3R1	C0004114	Astrocytoma	0.0002747267842131	BEFREE
5295	PIK3R1	C0004364	Autoimmune Diseases	0.0002747267842131	BEFREE
5295	PIK3R1	C0005684	Malignant neoplasm of urinary bladder	0.0002747267842131	BEFREE
5295	PIK3R1	C0005695	Bladder Neoplasm	0.0002747267842131	BEFREE
5295	PIK3R1	C0007134	Renal Cell Carcinoma	0.0002747267842131	BEFREE
5295	PIK3R1	C0007138	Carcinoma, Transitional Cell	0.0002747267842131	BEFREE
5295	PIK3R1	C0011847	Diabetes	0.0002747267842131	BEFREE
5295	PIK3R1	C0011849	Diabetes Mellitus	0.0002747267842131	BEFREE
5295	PIK3R1	C0011881	Diabetic Nephropathy	0.0002747267842131	BEFREE
5295	PIK3R1	C0014170	Endometrial Neoplasms	0.0002747267842131	BEFREE
5295	PIK3R1	C0017638	Glioma	0.0002747267842131	BEFREE
5295	PIK3R1	C0019829	Hodgkin Disease	0.0002747267842131	BEFREE
5295	PIK3R1	C0022118	Transient ischemia	0.0002747267842131	BEFREE
5295	PIK3R1	C0023434	Chronic Lymphocytic Leukemia	0.0002747267842131	BEFREE
5295	PIK3R1	C0023467	Leukemia, Myelocytic, Acute	0.0002747267842131	BEFREE
5295	PIK3R1	C0025958	Microcephaly	0.0002747267842131	BEFREE
5295	PIK3R1	C0026764	Multiple Myeloma	0.0002747267842131	BEFREE
5295	PIK3R1	C0027819	Neuroblastoma	0.0002747267842131	BEFREE
5295	PIK3R1	C0029408	Degenerative polyarthritis	0.0002747267842131	BEFREE
5295	PIK3R1	C0029927	Ovarian Cysts	0.0002747267842131	BEFREE