Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PIK3R1	8979	COSM6946641,	lung	carcinoma	p.D421Y	Substitution - Missense	5:68293445-68293445,	PATHOGENIC	0.99883	28481359
PIK3R1	8979	COSM6958593,	pancreas	carcinoma	p.M1V	Substitution - Missense	5:68226676-68226676,	PATHOGENIC	0.99862	28481359
PIK3R1	8979	COSM41124,	central_nervous_system	glioma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99851	18772396
PIK3R1	8979	COSM41124,	skin	malignant_melanoma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99851	28481359
PIK3R1	8979	COSM6937346,	stomach	carcinoma	p.R724*	Substitution - Nonsense	5:68297596-68297596,	PATHOGENIC	0.99849	28481359
PIK3R1	8979	COSM6935759,	large_intestine	carcinoma	p.W583*	Substitution - Nonsense	5:68295423-68295423,	PATHOGENIC	0.99831	28481359
PIK3R1	8979	COSM5760562,	central_nervous_system	glioma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99823	28481359
PIK3R1	8979	COSM5760562,	endometrium	carcinoma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99823	28481359
PIK3R1	8979	COSM5760562,	prostate	carcinoma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99823	28481359
PIK3R1	8979	COSM5760562,	central_nervous_system	glioma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99823	26919320
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	18772396
PIK3R1	8979	COSM35827,	large_intestine	carcinoma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	lung	carcinoma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	18772396
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM6956942,	skin	carcinoma	p.K587I	Substitution - Missense	5:68295434-68295434,	PATHOGENIC	0.99818	28481359
PIK3R1	8979	COSM85889,	kidney	carcinoma	p.?	Unknown	5:68295418-68295418,	PATHOGENIC	0.99809	28481359
PIK3R1	8979	COSM2155617,	soft_tissue	liposarcoma	p.K379E	Substitution - Missense	5:68293319-68293319,	PATHOGENIC	0.99801	28481359
PIK3R1	8979	COSM6984406,	endometrium	carcinoma	p.V437L	Substitution - Missense	5:68293718-68293718,	PATHOGENIC	0.99791	28481359
PIK3R1	8979	COSM6978024,	skin	malignant_melanoma	p.Q432*	Substitution - Nonsense	5:68293478-68293478,	PATHOGENIC	0.9978	28481359
PIK3R1	8979	COSM6957994,	central_nervous_system	glioma	p.?	Unknown	5:68293835-68293835,	PATHOGENIC	0.99769	28481359
PIK3R1	8979	COSM6969580,	lung	carcinoma	p.H407R	Substitution - Missense	5:68293404-68293404,	PATHOGENIC	0.99764	28481359
PIK3R1	8979	COSM249900,	ovary	carcinoma	p.?	Unknown	5:68293835-68293835,	PATHOGENIC	0.99757	22214849
PIK3R1	8979	COSM3856086,	prostate	carcinoma	p.?	Unknown	5:68293835-68293835,	PATHOGENIC	0.99726	28481359
PIK3R1	8979	COSM6947171,	prostate	carcinoma	p.E596*	Substitution - Nonsense	5:68295460-68295460,	PATHOGENIC	0.9972	28481359
PIK3R1	8979	COSM6979196,	kidney	carcinoma	p.Q586*	Substitution - Nonsense	5:68295430-68295430,	PATHOGENIC	0.99719	28481359
PIK3R1	8979	COSM6979196,	kidney	carcinoma	p.Q586*	Substitution - Nonsense	5:68295430-68295430,	PATHOGENIC	0.99719	28481359
PIK3R1	8979	COSM4877550,	skin	carcinoma	p.A360V	Substitution - Missense	5:68293160-68293160,	PATHOGENIC	0.99718	28481359
PIK3R1	8979	COSM87220,	large_intestine	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	28481359
PIK3R1	8979	COSM87220,	endometrium	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	21478295
PIK3R1	8979	COSM87220,	large_intestine	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	28481359
PIK3R1	8979	COSM87220,	large_intestine	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	28481359
PIK3R1	8979	COSM87220,	large_intestine	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	23700467
PIK3R1	8979	COSM6920262,	breast	carcinoma	p.?	Unknown	5:68293708-68293708,	PATHOGENIC	0.99705	28481359
PIK3R1	8979	COSM6945963,	prostate	carcinoma	p.?	Unknown	5:68293707-68293707,	PATHOGENIC	0.99686	28481359
PIK3R1	8979	COSM6951607,	ovary	carcinoma	p.?	Unknown	5:68293707-68293707,	PATHOGENIC	0.99671	28481359
PIK3R1	8979	COSM6951607,	central_nervous_system	glioma	p.?	Unknown	5:68293707-68293707,	PATHOGENIC	0.99671	28481359
PIK3R1	8979	COSM5609855,	skin	malignant_melanoma	p.Q591L	Substitution - Missense	5:68295446-68295446,	PATHOGENIC	0.99644	26343386
PIK3R1	8979	COSM6935288,	endometrium	carcinoma	p.N441H	Substitution - Missense	5:68293730-68293730,	PATHOGENIC	0.99602	28481359
PIK3R1	8979	COSM6971814,	large_intestine	carcinoma	p.E218*	Substitution - Nonsense	5:68280545-68280545,	PATHOGENIC	0.99558	28481359
PIK3R1	8979	COSM5945952,	skin	malignant_melanoma	p.D352G	Substitution - Missense	5:68293136-68293136,	PATHOGENIC	0.99558	26744134
PIK3R1	8979	COSM5868746,	NS	carcinoma	p.Q475*	Substitution - Nonsense	5:68293832-68293832,	PATHOGENIC	0.99545	28481359
PIK3R1	8979	COSM6947044,	central_nervous_system	glioma	p.W597G	Substitution - Missense	5:68295463-68295463,	PATHOGENIC	0.9954	28481359
PIK3R1	8979	COSM6951785,	central_nervous_system	glioma	p.E342K	Substitution - Missense	5:68293105-68293105,	PATHOGENIC	0.99537	28481359
PIK3R1	8979	COSM5868743,	pancreas	carcinoma	p.G353R	Substitution - Missense	5:68293138-68293138,	PATHOGENIC	0.99537	27203738
PIK3R1	8979	COSM6966414,	urinary_tract	carcinoma	p.E345K	Substitution - Missense	5:68293114-68293114,	PATHOGENIC	0.99537	28481359
PIK3R1	8979	COSM6995472,	ovary	germ_cell_tumour	p.D394H	Substitution - Missense	5:68293364-68293364,	PATHOGENIC	0.99505	28954785
PIK3R1	8979	COSM6940802,	prostate	carcinoma	p.M364I	Substitution - Missense	5:68293173-68293173,	PATHOGENIC	0.99502	28481359
PIK3R1	8979	COSM94999,	breast	carcinoma	p.A634P	Substitution - Missense	5:68296256-68296256,	PATHOGENIC	0.99466	20668451
PIK3R1	8979	COSM6919239,	large_intestine	carcinoma	p.K592N	Substitution - Missense	5:68295450-68295450,	PATHOGENIC	0.99418	28481359
PIK3R1	8979	COSM6945434,	breast	carcinoma	p.E635*	Substitution - Nonsense	5:68296259-68296259,	PATHOGENIC	0.99416	28481359
PIK3R1	8979	COSM6966391,	lung	carcinoma	p.D168G	Substitution - Missense	5:68279602-68279602,	PATHOGENIC	0.99412	28481359
PIK3R1	8979	COSM87544,	breast	carcinoma	p.R574T	Substitution - Missense	5:68295300-68295300,	PATHOGENIC	0.99369	20668451
PIK3R1	8979	COSM87544,	urinary_tract	carcinoma	p.R574T	Substitution - Missense	5:68295300-68295300,	PATHOGENIC	0.99369	21533174
PIK3R1	8979	COSM6920205,	lung	carcinoma	p.E403K	Substitution - Missense	5:68293391-68293391,	PATHOGENIC	0.99369	28481359
PIK3R1	8979	COSM6932411,	large_intestine	carcinoma	p.E683*	Substitution - Nonsense	5:68297473-68297473,	PATHOGENIC	0.99345	28481359
PIK3R1	8979	COSM85930,	large_intestine	carcinoma	p.R649Q	Substitution - Missense	5:68296302-68296302,	PATHOGENIC	0.99333	19962665
PIK3R1	8979	COSM1645452,	large_intestine	carcinoma	p.F268C	Substitution - Missense	5:68280696-68280696,	PATHOGENIC	0.99331	23700467
PIK3R1	8979	COSM85927,	large_intestine	carcinoma	p.R574I	Substitution - Missense	5:68295300-68295300,	PATHOGENIC	0.99311	23680147
PIK3R1	8979	COSM39583,	central_nervous_system	glioma	p.D464H	Substitution - Missense	5:68293799-68293799,	PATHOGENIC	0.99311	18772396
PIK3R1	8979	COSM85927,	large_intestine	carcinoma	p.R574I	Substitution - Missense	5:68295300-68295300,	PATHOGENIC	0.99311	19962665
PIK3R1	8979	COSM6975787,	skin	carcinoma	p.E284K	Substitution - Missense	5:68280940-68280940,	PATHOGENIC	0.99309	28481359
PIK3R1	8979	COSM6961148,	pancreas	carcinoma	p.R481M	Substitution - Missense	5:68294552-68294552,	PATHOGENIC	0.99308	28481359
PIK3R1	8979	COSM6940118,	large_intestine	carcinoma	p.E489*	Substitution - Nonsense	5:68294575-68294575,	PATHOGENIC	0.99308	28481359
PIK3R1	8979	COSM6950110,	skin	malignant_melanoma	p.E546*	Substitution - Nonsense	5:68295215-68295215,	PATHOGENIC	0.99262	28481359
PIK3R1	8979	COSM35765,	breast	carcinoma	p.D560Y	Substitution - Missense	5:68295257-68295257,	PATHOGENIC	0.99262	28481359
PIK3R1	8979	COSM35765,	large_intestine	carcinoma	p.D560Y	Substitution - Missense	5:68295257-68295257,	PATHOGENIC	0.99262	28481359
PIK3R1	8979	COSM35765,	breast	carcinoma	p.D560Y	Substitution - Missense	5:68295257-68295257,	PATHOGENIC	0.99262	22538770
PIK3R1	8979	COSM85932,	large_intestine	carcinoma	p.E666K	Substitution - Missense	5:68297422-68297422,	PATHOGENIC	0.99257	19962665
PIK3R1	8979	COSM6912658,	lung	carcinoma	p.E469*	Substitution - Nonsense	5:68293814-68293814,	PATHOGENIC	0.99257	28481359
PIK3R1	8979	COSM6968601,	endometrium	carcinoma	p.E468*	Substitution - Nonsense	5:68293811-68293811,	PATHOGENIC	0.99257	28481359
PIK3R1	8979	COSM6937072,	cervix	carcinoma	p.D620G	Substitution - Missense	5:68296215-68296215,	PATHOGENIC	0.9918	28481359
PIK3R1	8979	COSM6915545,	large_intestine	carcinoma	p.E507*	Substitution - Nonsense	5:68294629-68294629,	PATHOGENIC	0.99135	28481359
PIK3R1	8979	COSM87229,	endometrium	carcinoma	p.E495*	Substitution - Nonsense	5:68294593-68294593,	PATHOGENIC	0.99135	21478295
PIK3R1	8979	COSM6952611,	urinary_tract	carcinoma	p.E614K	Substitution - Missense	5:68296196-68296196,	PATHOGENIC	0.99116	28481359
PIK3R1	8979	COSM6944764,	central_nervous_system	glioma	p.T473P	Substitution - Missense	5:68293826-68293826,	PATHOGENIC	0.99109	28481359
PIK3R1	8979	COSM5766196,	central_nervous_system	glioma	p.E518*	Substitution - Nonsense	5:68294662-68294662,	PATHOGENIC	0.99106	26919320
PIK3R1	8979	COSM6960758,	stomach	carcinoma	p.N488D	Substitution - Missense	5:68294572-68294572,	PATHOGENIC	0.99071	28481359
PIK3R1	8979	COSM6960758,	stomach	carcinoma	p.N488D	Substitution - Missense	5:68294572-68294572,	PATHOGENIC	0.99071	28481359
PIK3R1	8979	COSM5609852,	skin	malignant_melanoma	p.H385Y	Substitution - Missense	5:68293337-68293337,	PATHOGENIC	0.99056	26343386
PIK3R1	8979	COSM5609852,	NS	malignant_melanoma	p.H385Y	Substitution - Missense	5:68293337-68293337,	PATHOGENIC	0.99056	28481359
PIK3R1	8979	COSM1069611,	upper_aerodigestive_tract	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	25056374
PIK3R1	8979	COSM1069611,	endometrium	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	large_intestine	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM6954716,	lung	carcinoma	p.D569G	Substitution - Missense	5:68295285-68295285,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	large_intestine	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	central_nervous_system	glioma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	large_intestine	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	salivary_gland	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	27334835
PIK3R1	8979	COSM1069611,	endometrium	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	endometrium	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28485815
PIK3R1	8979	COSM1069611,	large_intestine	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM6913413,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q241*	Substitution - Nonsense	5:68280614-68280614,	PATHOGENIC	0.99047	28481359
PIK3R1	8979	COSM6913413,	urinary_tract	carcinoma	p.Q241*	Substitution - Nonsense	5:68280614-68280614,	PATHOGENIC	0.99047	28481359
PIK3R1	8979	COSM6919242,	large_intestine	carcinoma	p.S709Y	Substitution - Missense	5:68297552-68297552,	PATHOGENIC	0.9904	28481359
PIK3R1	8979	COSM42912,	lung	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	endometrium	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	21478295
PIK3R1	8979	COSM42912,	endometrium	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	large_intestine	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	large_intestine	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	central_nervous_system	glioma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	central_nervous_system	glioma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	salivary_gland	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	27334835
PIK3R1	8979	COSM42912,	soft_tissue	synovial_sarcoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	central_nervous_system	glioma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	central_nervous_system	glioma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	large_intestine	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	19962665
PIK3R1	8979	COSM42912,	endometrium	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28485815
PIK3R1	8979	COSM42912,	large_intestine	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	stomach	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	26489445
PIK3R1	8979	COSM39403,	central_nervous_system	glioma	p.K459E	Substitution - Missense	5:68293784-68293784,	PATHOGENIC	0.99034	18772396
PIK3R1	8979	COSM6927471,	central_nervous_system	glioma	p.E510K	Substitution - Missense	5:68294638-68294638,	PATHOGENIC	0.99026	28481359
PIK3R1	8979	COSM6937429,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	5:68280730-68280730,	PATHOGENIC	0.98964	28481359
PIK3R1	8979	COSM6941357,	large_intestine	carcinoma	p.N527D	Substitution - Missense	5:68295158-68295158,	PATHOGENIC	0.98948	28481359
PIK3R1	8979	COSM1438323,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D560G	Substitution - Missense	5:68295258-68295258,	PATHOGENIC	0.98948	28481359
PIK3R1	8979	COSM87235,	endometrium	carcinoma	p.D548G	Substitution - Missense	5:68295222-68295222,	PATHOGENIC	0.98948	21478295
PIK3R1	8979	COSM6969915,	liver	carcinoma	p.R523K	Substitution - Missense	5:68294678-68294678,	PATHOGENIC	0.98908	28481359
PIK3R1	8979	COSM327132,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q455K	Substitution - Missense	5:68293772-68293772,	PATHOGENIC	0.98818	22675565
PIK3R1	8979	COSM6969395,	endometrium	carcinoma	p.P717S	Substitution - Missense	5:68297575-68297575,	PATHOGENIC	0.98758	28481359
PIK3R1	8979	COSM6965407,	endometrium	carcinoma	p.Q721*	Substitution - Nonsense	5:68297587-68297587,	PATHOGENIC	0.98758	28481359
PIK3R1	8979	COSM6932328,	large_intestine	carcinoma	p.H697Y	Substitution - Missense	5:68297515-68297515,	PATHOGENIC	0.9875	28481359
PIK3R1	8979	COSM6928921,	central_nervous_system	glioma	p.E601K	Substitution - Missense	5:68295475-68295475,	PATHOGENIC	0.98717	28481359
PIK3R1	8979	COSM257732,	skin	malignant_melanoma	p.R386*	Substitution - Nonsense	5:68293340-68293340,	PATHOGENIC	0.98695	28481359
PIK3R1	8979	COSM6941886,	breast	carcinoma	p.L647V	Substitution - Missense	5:68296295-68296295,	PATHOGENIC	0.98682	28481359
PIK3R1	8979	COSM5609858,	skin	malignant_melanoma	p.L570H	Substitution - Missense	5:68295288-68295288,	PATHOGENIC	0.9865	26343386
PIK3R1	8979	COSM6911220,	endometrium	carcinoma	p.Y580N	Substitution - Missense	5:68295317-68295317,	PATHOGENIC	0.9865	28481359
PIK3R1	8979	COSM5766197,	central_nervous_system	glioma	p.L449*	Substitution - Nonsense	5:68293755-68293755,	PATHOGENIC	0.98643	26919320
PIK3R1	8979	COSM6913486,	skin	carcinoma	p.Q478*	Substitution - Nonsense	5:68294542-68294542,	PATHOGENIC	0.986	28481359
PIK3R1	8979	COSM6951151,	cervix	carcinoma	p.S690F	Substitution - Missense	5:68297495-68297495,	PATHOGENIC	0.98589	28481359
PIK3R1	8979	COSM85933,	large_intestine	carcinoma	p.A682V	Substitution - Missense	5:68297471-68297471,	PATHOGENIC	0.98589	19962665
PIK3R1	8979	COSM6957358,	penis	carcinoma	p.R590W	Substitution - Missense	5:68295442-68295442,	PATHOGENIC	0.98557	28481359
PIK3R1	8979	COSM40940,	endometrium	carcinoma	p.L570P	Substitution - Missense	5:68295288-68295288,	PATHOGENIC	0.98459	28481359
PIK3R1	8979	COSM40940,	central_nervous_system	glioma	p.L570P	Substitution - Missense	5:68295288-68295288,	PATHOGENIC	0.98459	28481359
PIK3R1	8979	COSM40940,	central_nervous_system	glioma	p.L570P	Substitution - Missense	5:68295288-68295288,	PATHOGENIC	0.98459	18772396
PIK3R1	8979	COSM1069619,	endometrium	carcinoma	p.L573P	Substitution - Missense	5:68295297-68295297,	PATHOGENIC	0.98459	28485815
PIK3R1	8979	COSM1069619,	large_intestine	carcinoma	p.L573P	Substitution - Missense	5:68295297-68295297,	PATHOGENIC	0.98459	28481359
PIK3R1	8979	COSM6980078,	large_intestine	carcinoma	p.A331V	Substitution - Missense	5:68292334-68292334,	PATHOGENIC	0.98451	28481359
PIK3R1	8979	COSM6957987,	endometrium	carcinoma	p.L584F	Substitution - Missense	5:68295426-68295426,	PATHOGENIC	0.98444	28481359
PIK3R1	8979	COSM6952187,	large_intestine	carcinoma	p.D615Y	Substitution - Missense	5:68296199-68296199,	PATHOGENIC	0.98404	28481359
PIK3R1	8979	COSM87232,	endometrium	carcinoma	p.Y334*	Substitution - Nonsense	5:68292344-68292344,	PATHOGENIC	0.98389	21478295
PIK3R1	8979	COSM85936,	breast	carcinoma	p.L449S	Substitution - Missense	5:68293755-68293755,	PATHOGENIC	0.98363	19962665
PIK3R1	8979	COSM6971168,	lung	carcinoma	p.W333R	Substitution - Missense	5:68292339-68292339,	PATHOGENIC	0.98324	28481359
PIK3R1	8979	COSM1645453,	large_intestine	carcinoma	p.F268L	Substitution - Missense	5:68280697-68280697,	PATHOGENIC	0.9797	23700467
PIK3R1	8979	COSM1717421,	breast	carcinoma	p.R642L	Substitution - Missense	5:68296281-68296281,	PATHOGENIC	0.97875	24229379
PIK3R1	8979	COSM6930170,	lung	carcinoma	p.E140K	Substitution - Missense	5:68273473-68273473,	PATHOGENIC	0.97578	28481359
PIK3R1	8979	COSM6930170,	urinary_tract	carcinoma	p.E140K	Substitution - Missense	5:68273473-68273473,	PATHOGENIC	0.97578	28481359
PIK3R1	8979	COSM5945951,	skin	malignant_melanoma	p.E137G	Substitution - Missense	5:68273465-68273465,	PATHOGENIC	0.97521	26744134
PIK3R1	8979	COSM6935287,	endometrium	carcinoma	p.S229L	Substitution - Missense	5:68280579-68280579,	PATHOGENIC	0.97187	28481359
PIK3R1	8979	COSM6955995,	breast	carcinoma	p.R562P	Substitution - Missense	5:68295264-68295264,	PATHOGENIC	0.97111	28481359
PIK3R1	8979	COSM1581456,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A210D	Substitution - Missense	5:68279728-68279728,	PATHOGENIC	0.96987	23292937
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	19962665
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	28481359
PIK3R1	8979	COSM85926,	skin	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	25589618
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	23680147
PIK3R1	8979	COSM85926,	endometrium	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	21478295
PIK3R1	8979	COSM85926,	endometrium	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	21478295
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	19962665
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	28481359
PIK3R1	8979	COSM85937,	large_intestine	carcinoma	p.R543I	Substitution - Missense	5:68295207-68295207,	PATHOGENIC	0.96364	19962665
PIK3R1	8979	COSM4413604,	endometrium	carcinoma	p.Y698*	Substitution - Nonsense	5:68297520-68297520,	PATHOGENIC	0.96096	25308272
PIK3R1	8979	COSM6971613,	skin	carcinoma	p.Y203C	Substitution - Missense	5:68279707-68279707,	PATHOGENIC	0.95924	28481359
PIK3R1	8979	COSM6909497,	urinary_tract	carcinoma	p.A277P	Substitution - Missense	5:68280722-68280722,	PATHOGENIC	0.95676	28481359
PIK3R1	8979	COSM6904275,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R523S	Substitution - Missense	5:68295148-68295148,	PATHOGENIC	0.95103	27248180
PIK3R1	8979	COSM6930387,	lung	carcinoma	p.D126Y	Substitution - Missense	5:68273431-68273431,	PATHOGENIC	0.94932	28481359
PIK3R1	8979	COSM6974678,	large_intestine	carcinoma	p.F247L	Substitution - Missense	5:68280634-68280634,	PATHOGENIC	0.9493	28481359
PIK3R1	8979	COSM6975487,	large_intestine	carcinoma	p.L449I	Substitution - Missense	5:68293754-68293754,	PATHOGENIC	0.94803	28481359
PIK3R1	8979	COSM6946640,	lung	carcinoma	p.R262G	Substitution - Missense	5:68280677-68280677,	PATHOGENIC	0.94489	28481359
PIK3R1	8979	COSM3727824,	upper_aerodigestive_tract	carcinoma	p.M326I	Substitution - Missense	5:68292320-68292320,	PATHOGENIC	0.94368	24667986
PIK3R1	8979	COSM3727824,	breast	carcinoma	p.M326I	Substitution - Missense	5:68292320-68292320,	PATHOGENIC	0.94368	28270497
PIK3R1	8979	COSM3071985,	prostate	carcinoma	p.R639*	Substitution - Nonsense	5:68296271-68296271,	PATHOGENIC	0.94286	20579941
PIK3R1	8979	COSM3071985,	large_intestine	carcinoma	p.R639*	Substitution - Nonsense	5:68296271-68296271,	PATHOGENIC	0.94286	28481359
PIK3R1	8979	COSM3071985,	prostate	carcinoma	p.R639*	Substitution - Nonsense	5:68296271-68296271,	PATHOGENIC	0.94286	20579941
PIK3R1	8979	COSM3071985,	prostate	carcinoma	p.R639*	Substitution - Nonsense	5:68296271-68296271,	PATHOGENIC	0.94286	20579941
PIK3R1	8979	COSM3975610,	breast	carcinoma	p.A185T	Substitution - Missense	5:68279652-68279652,	PATHOGENIC	0.93885	28270497
PIK3R1	8979	COSM3617617,	central_nervous_system	glioma	p.Y463*	Substitution - Nonsense	5:68293798-68293798,	PATHOGENIC	0.93637	28481359
PIK3R1	8979	COSM87233,	endometrium	carcinoma	p.R301*	Substitution - Nonsense	5:68280991-68280991,	PATHOGENIC	0.9352	21478295
PIK3R1	8979	COSM6980330,	kidney	carcinoma	p.T148I	Substitution - Missense	5:68273954-68273954,	PATHOGENIC	0.93007	28481359
PIK3R1	8979	COSM6966307,	breast	carcinoma	p.R465*	Substitution - Nonsense	5:68293802-68293802,	PATHOGENIC	0.92919	28481359
PIK3R1	8979	COSM6912989,	lung	carcinoma	p.Q214L	Substitution - Missense	5:68280534-68280534,	PATHOGENIC	0.92742	28481359
PIK3R1	8979	COSM5836057,	central_nervous_system	glioma	p.P116T	Substitution - Missense	5:68273401-68273401,	PATHOGENIC	0.92466	26919320
PIK3R1	8979	COSM3429594,	large_intestine	carcinoma	p.S208Y	Substitution - Missense	5:68279722-68279722,	PATHOGENIC	0.92236	28481359
PIK3R1	8979	COSM3429594,	endometrium	carcinoma	p.S208Y	Substitution - Missense	5:68279722-68279722,	PATHOGENIC	0.92236	28481359
PIK3R1	8979	COSM6949112,	skin	carcinoma	p.S254F	Substitution - Missense	5:68280654-68280654,	PATHOGENIC	0.91712	28481359
PIK3R1	8979	COSM6968479,	central_nervous_system	glioma	p.T283I	Substitution - Missense	5:68280938-68280938,	PATHOGENIC	0.91494	28481359
PIK3R1	8979	COSM5356390,	endometrium	carcinoma	p.R503W	Substitution - Missense	5:68294617-68294617,	PATHOGENIC	0.9145	28481359
PIK3R1	8979	COSM85931,	large_intestine	carcinoma	p.R642*	Substitution - Nonsense	5:68296280-68296280,	PATHOGENIC	0.91404	19962665
PIK3R1	8979	COSM85931,	skin	carcinoma	p.R642*	Substitution - Nonsense	5:68296280-68296280,	PATHOGENIC	0.91404	28481359
PIK3R1	8979	COSM5609861,	skin	malignant_melanoma	p.S147L	Substitution - Missense	5:68273951-68273951,	PATHOGENIC	0.90457	26343386
PIK3R1	8979	COSM85928,	large_intestine	carcinoma	p.N527K	Substitution - Missense	5:68295160-68295160,	PATHOGENIC	0.90016	19962665
PIK3R1	8979	COSM6921639,	prostate	carcinoma	p.N157H	Substitution - Missense	5:68273980-68273980,	PATHOGENIC	0.89157	28481359
PIK3R1	8979	COSM6965694,	endometrium	carcinoma	p.F646L	Substitution - Missense	5:68296294-68296294,	PATHOGENIC	0.88975	28481359
PIK3R1	8979	COSM1695845,	large_intestine	carcinoma	p.R557*	Substitution - Nonsense	5:68295248-68295248,	PATHOGENIC	0.88855	28481359
PIK3R1	8979	COSM1695845,	central_nervous_system	glioma	p.R557*	Substitution - Nonsense	5:68295248-68295248,	PATHOGENIC	0.88855	28481359
PIK3R1	8979	COSM1695845,	skin	malignant_melanoma	p.R557*	Substitution - Nonsense	5:68295248-68295248,	PATHOGENIC	0.88855	26343386
PIK3R1	8979	COSM6932327,	large_intestine	carcinoma	p.A183T	Substitution - Missense	5:68279646-68279646,	PATHOGENIC	0.88778	28481359
PIK3R1	8979	COSM6937716,	urinary_tract	carcinoma	p.E120D	Substitution - Missense	5:68273415-68273415,	PATHOGENIC	0.88043	28481359
PIK3R1	8979	COSM87226,	endometrium	carcinoma	p.C498*	Substitution - Nonsense	5:68294604-68294604,	PATHOGENIC	0.87361	21478295
PIK3R1	8979	COSM6982684,	endometrium	carcinoma	p.L616V	Substitution - Missense	5:68296202-68296202,	PATHOGENIC	0.87005	28481359
PIK3R1	8979	COSM87241,	skin	malignant_melanoma	p.D434_Q475del	Deletion - In frame	5:68293836-68293836,	PATHOGENIC	0.86427	28481359
PIK3R1	8979	COSM87241,	endometrium	carcinoma	p.D434_Q475del	Deletion - In frame	5:68293836-68293836,	PATHOGENIC	0.86427	21478295
PIK3R1	8979	COSM6980936,	lung	carcinoma	p.L209F	Substitution - Missense	5:68279726-68279726,	PATHOGENIC	0.86402	28481359
PIK3R1	8979	COSM6980936,	lung	carcinoma	p.L209F	Substitution - Missense	5:68279726-68279726,	PATHOGENIC	0.86402	28481359
PIK3R1	8979	COSM6986093,	breast	carcinoma	p.I133M	Substitution - Missense	5:68273454-68273454,	PATHOGENIC	0.8511	28481359
PIK3R1	8979	COSM327131,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T454I	Substitution - Missense	5:68293770-68293770,	PATHOGENIC	0.84329	22675565
PIK3R1	8979	COSM5019326,	soft_tissue	haemangioblastoma	p.I207I	Substitution - coding silent	5:68279720-68279720,	PATHOGENIC	0.82709	25589003
PIK3R1	8979	COSM5019326,	soft_tissue	haemangioblastoma	p.I207I	Substitution - coding silent	5:68279720-68279720,	PATHOGENIC	0.82709	25589003
PIK3R1	8979	COSM85934,	large_intestine	carcinoma	p.R162*	Substitution - Nonsense	5:68273995-68273995,	PATHOGENIC	0.79909	19962665
PIK3R1	8979	COSM87237,	endometrium	carcinoma	p.Q475_E476>IMLQ	Complex - insertion inframe	5:68294523-68294523,	PATHOGENIC	0.7737	21478295
PIK3R1	8979	COSM43181,	large_intestine	carcinoma	p.R461*	Substitution - Nonsense	5:68293790-68293790,	PATHOGENIC	0.72335	28481359
PIK3R1	8979	COSM5609849,	skin	malignant_melanoma	p.R649R	Substitution - coding silent	5:68296303-68296303,	NEUTRAL	0.47115	26343386
PIK3R1	8979	COSM6444825,	endometrium	carcinoma	p.I220T	Substitution - Missense	5:68280552-68280552,	NEUTRAL	0.44253	27159395
PIK3R1	8979	COSM6444825,	endometrium	carcinoma	p.I220T	Substitution - Missense	5:68280552-68280552,	NEUTRAL	0.44253	27159395
PIK3R1	8979	COSM87242,	endometrium	carcinoma	p.?	Unknown	5:68294515-68294515,	NEUTRAL	0.20149	21478295
PIK3R1	8979	COSM85925,	large_intestine	carcinoma	p.N285H	Substitution - Missense	5:68280943-68280943,	NEUTRAL	0.19591	19962665
PIK3R1	8979	COSM6933741,	lung	carcinoma	p.T169A	Substitution - Missense	5:68279604-68279604,	NEUTRAL	0.03541	28481359
PIK3R1	8979	COSM4604513,	upper_aerodigestive_tract	carcinoma	p.T576T	Substitution - coding silent	5:68295307-68295307,	NEUTRAL	0.03347	25056374
PIK3R1	8979	COSM87243,	endometrium	carcinoma	p.?	Unknown	5:68293278-68293278,	NEUTRAL	0.03288	21478295
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	breast	carcinoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	28270497
PIK3R1	8979	COSM5752295,	breast	carcinoma	p.?	Unknown	5:68295317-68295326,	Info_not_available	Info_not_available	28685160
PIK3R1	8979	COSM5945733,	breast	carcinoma	p.E451_Y452del	Deletion - In frame	Info_not_available	Info_not_available	Info_not_available	28921573
PIK3R1	8979	COSM6906496, COSM6906584, COSM6906742, COSM6906745,	breast, endometrium, large_intestine	carcinoma	p.L449_H450>Y, p.P568_T576delPDLIQLRKT, p.S460delS, p.V436fs*8	Complex - deletion inframe, Deletion - Frameshift, Deletion - In frame	5:68293714-68293736, 5:68293755-68293757, 5:68293787-68293789, 5:68295282-68295308,	Info_not_available	Info_not_available	29420467
PIK3R1	8979	COSM53577, COSM54575,	breast, central_nervous_system	carcinoma, glioma	p.453_454insN, p.L380del	Deletion - In frame, Insertion - In frame	5:68293322-68293324, 5:68293767-68293768,	Info_not_available	Info_not_available	Info_not_available
PIK3R1	8979	COSM85884, COSM85885, COSM85886, COSM85887, COSM85888,	large_intestine, ovary	carcinoma	p.?, p.L570_D578del, p.L570_Q572del, p.M582_D605>I	Complex - deletion inframe, Deletion - In frame, Unknown	5:68295288-68295296, 5:68295288-68295314, 5:68295416-68295427, 5:68295420-68295488, 5:68295488-68295491,	Info_not_available	Info_not_available	11606375
PIK3R1	8979	COSM85939,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N636fs*26	Deletion - Frameshift	5:68296263-68296263,	Info_not_available	Info_not_available	11986952
PIK3R1	8979	COSM85883,	central_nervous_system	glioma	p.Y580fs*1	Deletion - Frameshift	5:68295319-68295599,	Info_not_available	Info_not_available	15605984
PIK3R1	8979	COSM33546,	breast	carcinoma	p.N453_T454insN	Insertion - In frame	5:68293767-68293768,	Info_not_available	Info_not_available	16959974
PIK3R1	8979	COSM43347,	skin	carcinoma	p.Q579fs*23	Insertion - Frameshift	5:68295314-68295315,	Info_not_available	Info_not_available	19634059
PIK3R1	8979	COSM85935, COSM85938,	large_intestine, pancreas	carcinoma	p.I381fs*15, p.K668_H669insLK	Deletion - Frameshift, Insertion - In frame	5:68293324-68293327, 5:68297431-68297432,	Info_not_available	Info_not_available	19962665
PIK3R1	8979	COSM39296, COSM87215, COSM87216, COSM87217, COSM87219, COSM87221, COSM87222, COSM87223, COSM87224, COSM87225, COSM87227, COSM87228, COSM87230, COSM87231, COSM87234, COSM87236, COSM87238, COSM87239, COSM87240,	endometrium	carcinoma	p.?, p.D434_Q475del, p.D464fs*2, p.E451_Y452del, p.F456_R461>S, p.F456_R461del, p.H450_E451del, p.K459del, p.K511fs*2, p.Q457_R461del, p.Q475_E476>VLQ, p.R542del, p.R574_T576del, p.R577_M582>K, p.S460fs*5, p.S702fs*26, p.T454_D464del, p.Y463_L466del, p.Y463fs*1	Complex - deletion inframe, Complex - insertion inframe, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Unknown	5:68293088-68293107, 5:68293757-68293762, 5:68293760-68293765, 5:68293767-68293799, 5:68293774-68293791, 5:68293776-68293792, 5:68293778-68293792, 5:68293781-68293782, 5:68293782-68293784, 5:68293795-68293796, 5:68293795-68293806, 5:68293808-68293836, 5:68294504-68294527, 5:68294639-68294640, 5:68295203-68295205, 5:68295298-68295306, 5:68295309-68295327, 5:68297529-68297530,	Info_not_available	Info_not_available	21478295
PIK3R1	8979	COSM132920, COSM132921, COSM132922, COSM132923, COSM132924, COSM132925, COSM132926, COSM132927, COSM132928, COSM132929,	endometrium	carcinoma	p.G376R, p.K567E, p.L570P, p.N260S, p.R386G, p.R557_D560del, p.R639*, p.S460fs*?, p.T473S, p.Y467_E468insGEYDRLYE	Deletion - In frame, Frameshift, Insertion - In frame, Substitution - Missense, Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	21984976
PIK3R1	8979	COSM249898, COSM249899, COSM249901,	ovary	carcinoma	p.?, p.E403_I405>D, p.N564fs*?	Complex - deletion inframe, Unknown	5:68294534-68294535,	Info_not_available	Info_not_available	22214849
PIK3R1	8979	COSM1155748,	skin	malignant_melanoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	22912864
PIK3R1	8979	COSM132921, COSM132922, COSM132924, COSM132926, COSM132928, COSM1716341, COSM1716342, COSM1716343, COSM1716344, COSM1716345,	endometrium	carcinoma	p.A331V, p.H180fs*?, p.K567E, p.L570P, p.N260S, p.Q586fs*?, p.R386G, p.R557_K561>Q, p.S460fs*?, p.Y467_E468insGEYDRLYE	Complex - deletion inframe, Frameshift, Insertion - In frame, Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	23674493
PIK3R1	8979	COSM3736943,	skin	malignant_melanoma	p.D464_E468>E	Complex - deletion inframe	5:68293801-68293812,	Info_not_available	Info_not_available	23851445
PIK3R1	8979	COSM3734746,	urinary_tract	carcinoma	p.I290fs*4	Frameshift	Info_not_available	Info_not_available	Info_not_available	24192927
PIK3R1	8979	COSM1717413, COSM1717414, COSM1717415, COSM1717416, COSM1717417, COSM1717418, COSM1717420, COSM35737,	breast	carcinoma	p.E451_F456del, p.K575_R577del, p.L449del, p.M563_N564ins13, p.P568_T576del, p.R574_K575insMR, p.T576del, p.Y580_L581del	Deletion - In frame, Insertion - In frame	5:68293754-68293756, 5:68293760-68293777, 5:68295267-68295268, 5:68295280-68295306, 5:68295302-68295303, 5:68295302-68295310, 5:68295306-68295308, 5:68295317-68295322,	Info_not_available	Info_not_available	24229379
PIK3R1	8979	COSM1069625, COSM5352279, COSM5415272,	endometrium	carcinoma	p.?fs*?, p.L570_I571insI, p.T576delT	Deletion - In frame, Insertion - In frame, Unknown	5:68295287-68295288, 5:68295304-68295306,	Info_not_available	Info_not_available	25233892
PIK3R1	8979	COSM5945733,	central_nervous_system	glioma	p.E451_Y452del	Deletion - In frame	Info_not_available	Info_not_available	Info_not_available	25257301
PIK3R1	8979	COSM132926, COSM4766159,	central_nervous_system	glioma	p.E462fs*?, p.K567E	Frameshift, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25529192
PIK3R1	8979	COSM5574323,	skin	malignant_melanoma	p.R348*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	25705882
PIK3R1	8979	COSM132926, COSM3727823, COSM5033545, COSM5033546, COSM5033547, COSM5033548, COSM5033549, COSM5033550, COSM5033551,	central_nervous_system	glioma	p.?, p.E468del, p.E469_Y470ins12, p.I405del, p.K567E, p.L449del, p.R557_I559del, p.S412Y, p.S429Y	Deletion - In frame, Insertion - In frame, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25740784
PIK3R1	8979	COSM5025133,	breast	carcinoma	p.L380fs*16	Deletion - Frameshift	5:68293320-68293323,	Info_not_available	Info_not_available	25850943
PIK3R1	8979	COSM6023852, COSM6023859,	upper_aerodigestive_tract	carcinoma	p.?, p.D569_L570insPD	Insertion - In frame, Unknown	5:68293872-68293873, 5:68295287-68295288,	Info_not_available	Info_not_available	25850957
PIK3R1	8979	COSM5991643,	breast	carcinoma	p.Y580fs*19	Frameshift	Info_not_available	Info_not_available	Info_not_available	25927147
PIK3R1	8979	COSM6024064, COSM6024529, COSM6024551,	NS	carcinoma	p.G599fs*63, p.K448fs*32, p.N564D	Frameshift, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26182302
PIK3R1	8979	COSM5977617,	central_nervous_system	glioma	p.?	Unknown	5:68295324-68295325,	Info_not_available	Info_not_available	26487540
PIK3R1	8979	COSM5352279, COSM5352280, COSM5352303, COSM5352304,	endometrium	carcinoma	p.?fs*?, p.A277T, p.L637M	Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	26492180
PIK3R1	8979	COSM132926,	breast	hyperplasia	p.K567E	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26718977
PIK3R1	8979	COSM5760561, COSM5878513,	central_nervous_system	glioma	p.?, p.?_?del	Deletion - In frame, Unknown	Info_not_available	Info_not_available	Info_not_available	26919320
PIK3R1	8979	COSM5352279, COSM5881435,	endometrium	carcinoma	p.?fs*?, p.Q579Y	Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	27170661
PIK3R1	8979	COSM6865940, COSM6865941, COSM6865942,	breast	carcinoma	p.E451_Y452>G, p.I571_Q572del, p.S460fs*5	Complex - deletion inframe, Deletion - In frame, Insertion - Frameshift	5:68293761-68293764, 5:68293787-68293788, 5:68295290-68295295,	Info_not_available	Info_not_available	27284958
PIK3R1	8979	COSM5967130,	salivary_gland	carcinoma	p.?	Unknown	5:68295325-68295326,	Info_not_available	Info_not_available	27334835
PIK3R1	8979	COSM5967250,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M582T	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27449473
PIK3R1	8979	COSM6849504, COSM6849505,	ovary	carcinoma	p.S295*, p.V445E	Substitution - Missense, Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	28125452
PIK3R1	8979	COSM318378,	breast	carcinoma	p.E462_R465delEYDR	Deletion - In frame	5:68293791-68293802,	Info_not_available	Info_not_available	28270497
PIK3R1	8979	COSM43200,	kidney	Wilms_tumour	p.R557_K561>Q	Complex - deletion inframe	5:68295249-68295260,	Info_not_available	Info_not_available	28326956
PIK3R1	8979	COSM6842056,	large_intestine	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	28465371
PIK3R1	8979	COSM5025133, COSM6904346, COSM6904348,	endometrium	carcinoma	p.A444_L449del, p.L380fs*16, p.N453_Q455del	Deletion - Frameshift, Deletion - In frame	5:68293320-68293323, 5:68293738-68293755, 5:68293766-68293774,	Info_not_available	Info_not_available	28485815
PIK3R1	8979	COSM6444623,	breast	other	p.L347del	Deletion - In frame	5:68293121-68293123,	Info_not_available	Info_not_available	28513873
PIK3R1	8979	COSM6908609,	upper_aerodigestive_tract	carcinoma	p.L637fs*25	Deletion - Frameshift	5:68296265-68296265,	Info_not_available	Info_not_available	28581676
PIK3R1	8979	COSM39296, COSM40466,	central_nervous_system	glioma	p.H450_E451del, p.I571I	Deletion - In frame, Substitution - coding silent	5:68293757-68293762, 5:68295292-68295292,	Info_not_available	0.58101, Info_not_available	18772396
PIK3R1	8979	COSM1069610, COSM1069615, COSM1069621, COSM1069625, COSM1069627, COSM1069642, COSM132841, COSM2157179, COSM256135, COSM3071873, COSM3071896, COSM3071915, COSM318378, COSM449998, COSM450000, COSM4747412, COSM5517036, COSM5752295, COSM5835072, COSM6908640, COSM6910286, COSM6910896, COSM6911320, COSM6912229, COSM6912677, COSM6913386, COSM6914541, COSM6914774, COSM6915221, COSM6916230, COSM6916270, COSM6916737, COSM6918007, COSM6919094, COSM6919113, COSM6920001, COSM6920094, COSM6920155, COSM6920275, COSM6920349, COSM6920913, COSM6922982, COSM6923461, COSM6925460, COSM6926373, COSM6928089, COSM6929688, COSM6929775, COSM6930032, COSM6930836, COSM6931056, COSM6931144, COSM6932742, COSM6933584, COSM6933958, COSM6934489, COSM6936386, COSM6936677, COSM6937108, COSM6938775, COSM6939067, COSM6939893, COSM6941407, COSM6943537, COSM6943561, COSM6945569, COSM6946695, COSM6946906, COSM6947091, COSM6948568, COSM6948571, COSM6949077, COSM6949084, COSM6949187, COSM6951161, COSM6951168, COSM6954259, COSM6954889, COSM6955601, COSM6955640, COSM6957736, COSM6958175, COSM6958234, COSM6958742, COSM6958961, COSM6959688, COSM6960267, COSM6962045, COSM6962224, COSM6962261, COSM6962285, COSM6964932, COSM6965412, COSM6965899, COSM6965902, COSM6966473, COSM6966518, COSM6966557, COSM6969149, COSM6969178, COSM6969184, COSM6969417, COSM6970234, COSM6971576, COSM6973866, COSM6974443, COSM6975105, COSM6975743, COSM6975746, COSM6975911, COSM6978346, COSM6978482, COSM6978512, COSM6979320, COSM6979520, COSM6979652, COSM6980288, COSM6980366, COSM6980518, COSM6981174, COSM6982512, COSM6983102, COSM6984217, COSM87216, COSM87228,	autonomic_ganglia, breast, central_nervous_system, cervix, endometrium, kidney, large_intestine, lung, ovary, prostate, salivary_gland, soft_tissue, stomach, thyroid, upper_aerodigestive_tract, urinary_tract	angiosarcoma, carcinoma, glioma, liposarcoma, neuroblastoma, other, solitary_fibrous_tumour	p.?, p.A486fs*6, p.D440_E451del12, p.D440_K448delDNIEAVGKK, p.D440delD, p.D464_R465ins12, p.D569_L581>E, p.D569fs*34, p.D578P, p.D578_M582>E, p.D578fs*23, p.D605fs*58, p.D708fs*8, p.E120_A123delEQFA, p.E403_L404>V, p.E451_Y452delEY, p.E451_Y452insHE, p.E458_K459delEK, p.E458delE, p.E462_R465delEYDR, p.E462_Y463>D, p.E462fs*2, p.E468_E469insDRLYE, p.E468_E469insGEYDRLYE, p.E468_E469insYDRLYE, p.E558_R562delEIDKR, p.E596fs*3, p.E650fs*8, p.F456_K459delFQEK, p.F456_Q457delFQ, p.F646_S652>LL, p.G100fs*15, p.G35fs*4, p.G446_L449>V, p.G588fs*7, p.G665fs*3, p.G678fs*9, p.H385fs*11, p.H450_E451delHE, p.H450_K459del10, p.H706fs*>20, p.I405_L420del16, p.I405delI, p.I442_N453del12, p.I442fs*30, p.I566_P568>T, p.I571_K575delIQLRK, p.I571_L581del11, p.I571_R574delIQLR, p.I571fs*31, p.I82fs*32, p.K447fs*31, p.K448_N453delKLHEYN, p.K448_Y452delKLHEY, p.K459del, p.K561fs*7, p.K567_I571delKPDLI, p.K567_L570delKPDL, p.K567delK, p.K575_L581>M, p.K575_R577delKTR, p.L356fs*17, p.L380delL, p.L380fs*1, p.L396fs*6, p.L449_H450insQ, p.L449_Y452>FH, p.L449delL, p.L449fs*3, p.L573_K575delLRK, p.L594V, p.L710fs*5, p.M326fs*6, p.M563fs*5, p.N282fs*3, p.N378delN, p.N441_T454del14, p.N453_Q455>K, p.N453_Q457delNTQFQ, p.N453_S460>K, p.N453delN, p.P568_L573delPDLIQL, p.P568fs*34, p.Q455_F456insHEYNTQ, p.Q572fs*33, p.R461_E462>Q, p.R465_L466insR, p.R557fs*6, p.R557fs*7, p.R574delR, p.R577_D578insKTR, p.R577_L581>SI, p.R577delR, p.R577fs*19, p.S155fs*23, p.S460_R461insQFQEKS, p.S460fs*20, p.S709_L710delSL, p.T576delT, p.T623fs*40, p.V401_H407delVVELINH, p.V402_L413del12, p.V661fs*3, p.V663fs*1, p.V671fs*15, p.Y334fs*6, p.Y390fs*6, p.Y452_N453insF, p.Y452_N453insY, p.Y452_Q457delYNTQFQ, p.Y463_D464insEKSREY, p.Y463_L466del, p.Y470_T471insDRLYEEY, p.Y580_L581>M	Complex - deletion inframe, Complex - frameshift, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Insertion - In frame, Substitution - Missense, Unknown	5:68226776-68226777, 5:68226913-68226913, 5:68226971-68226972, 5:68273408-68273419, 5:68273970-68274019, 5:68273973-68273974, 5:68280933-68280934, 5:68292316-68292317, 5:68292342-68292355, 5:68293144-68293144, 5:68293318-68293320, 5:68293321-68293323, 5:68293322-68293322, 5:68293331-68293332, 5:68293347-68293348, 5:68293368-68293377, 5:68293385-68293405, 5:68293388-68293423, 5:68293392-68293394, 5:68293392-68293439, 5:68293395-68293397, 5:68293698-68293772, 5:68293724-68293759, 5:68293725-68293751, 5:68293727-68293729, 5:68293728-68293763, 5:68293729-68293770, 5:68293733-68293757, 5:68293746-68293754, 5:68293747-68293748, 5:68293750-68293757, 5:68293751-68293768, 5:68293753-68293755, 5:68293753-68293768, 5:68293755-68293756, 5:68293756-68293761, 5:68293756-68293763, 5:68293756-68293785, 5:68293758-68293763, 5:68293761-68293778, 5:68293762-68293763, 5:68293763-68293764, 5:68293764-68293765, 5:68293764-68293766, 5:68293766-68293768, 5:68293766-68293780, 5:68293767-68293772, 5:68293768-68293789, 5:68293770-68293771, 5:68293771-68293776, 5:68293773-68293784, 5:68293779-68293784, 5:68293780-68293781, 5:68293781-68293785, 5:68293782-68293782, 5:68293782-68293784, 5:68293789-68293800, 5:68293790-68293791, 5:68293791-68293792, 5:68293791-68293793, 5:68293791-68293802, 5:68293792-68293793, 5:68293794-68293796, 5:68293795-68293806, 5:68293798-68293799, 5:68293801-68293802, 5:68294564-68294564, 5:68295248-68295262, 5:68295249-68295249, 5:68295249-68295262, 5:68295258-68295259, 5:68295264-68295265, 5:68295275-68295289, 5:68295276-68295281, 5:68295276-68295287, 5:68295277-68295278, 5:68295277-68295279, 5:68295278-68295279, 5:68295280-68295297, 5:68295281-68295282, 5:68295286-68295321, 5:68295287-68295288, 5:68295288-68295320, 5:68295290-68295301, 5:68295290-68295304, 5:68295290-68295417, 5:68295294-68295302, 5:68295297-68295298, 5:68295298-68295306, 5:68295299-68295301, 5:68295303-68295320, 5:68295304-68295306, 5:68295307-68295308, 5:68295307-68295309, 5:68295307-68295323, 5:68295310-68295322, 5:68295311-68295312, 5:68295313-68295324, 5:68295316-68295326, 5:68295317-68295320, 5:68295317-68295326, 5:68295325-68295325, 5:68295410-68295420, 5:68295414-68295419, 5:68295419-68295421, 5:68295431-68295431, 5:68295454-68295454, 5:68295460-68295467, 5:68295472-68295502, 5:68295485-68295486, 5:68296221-68296222, 5:68296294-68296312, 5:68296304-68296316, 5:68296329-68296330, 5:68296335-68296336, 5:68297419-68297419, 5:68297434-68297435, 5:68297456-68297471, 5:68297540-68297541, 5:68297547-68297548, 5:68297550-68297555, 5:68297552-68297552,	Info_not_available	0.51672, Info_not_available	28481359