Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ACVR2B Affinity Capture-MS physical 28514442 NA BioGRID ANKLE2 Affinity Capture-MS physical 28514442 NA BioGRID ATP6V0C coimmunoprecipitation physical association 1334459 0.40 IntAct, MINT ATR Affinity Capture-MS physical 28514442 NA BioGRID BCLAF1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct BMPR1A Affinity Capture-MS physical 28514442 NA BioGRID CAV1 Affinity Capture-Western, Co-fractionation, Reconstituted Complex physical 10066366 NA BioGRID CAV3 Reconstituted Complex physical 10066366 NA BioGRID CBL coimmunoprecipitation association 17620338 0.35 IntAct, MINT CBLB Affinity Capture-Western physical 27048651 NA BioGRID CGRRF1 Affinity Capture-MS physical 28514442 NA BioGRID COPA Affinity Capture-Western physical 9207175 NA BioGRID CRK Affinity Capture-Western, Reconstituted Complex, pull down association, physical 10733900 0.35 BioGRID, IntAct, MINT CRKL proximity ligation assay physical association 23397142 0.40 IntAct CTDNEP1 Affinity Capture-MS physical 28514442 NA BioGRID DEPDC1 Affinity Capture-MS physical 28514442 NA BioGRID EBI-4399559 anti bait coimmunoprecipitation physical association 21245321 0.40 IntAct EGFR Affinity Capture-Western physical 9506992 NA BioGRID EIF2AK2 Affinity Capture-Western physical 11350938 NA BioGRID ERRFI1 Affinity Capture-Western physical 19815557 NA BioGRID ETV6 Affinity Capture-Western physical 22262849 NA BioGRID FGD6 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct FNDC3A Affinity Capture-MS physical 28514442 NA BioGRID FOXK1 Affinity Capture-MS physical 26496610, 28514442 NA BioGRID FOXK1 anti tag coimmunoprecipitation association 26496610 0.35 IntAct FOXK2 Affinity Capture-MS physical 28514442 NA BioGRID FYN coimmunoprecipitation, pull down association 1661130, 7685273, 7687537 0.64 IntAct, MINT GRB10 pull down association 10454568 0.35 IntAct, MINT GRB14 Reconstituted Complex physical 8647858 NA BioGRID GRB2 Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, competition binding association, physical 10026169, 7935391, 9362449 0.46 BioGRID, IntAct, MINT GRB7 competition binding, pull down association 8940081 0.46 IntAct, MINT GRK2 Affinity Capture-Western physical 12381737 NA BioGRID HELLS Affinity Capture-MS physical 28514442 NA BioGRID HSP90AA1 Affinity Capture-Luminescence physical 22939624 NA BioGRID HSP90AB1 luminescence based mammalian interactome mapping physical association 22939624 0.40 IntAct HUS1 Affinity Capture-MS physical 28514442 NA BioGRID IL1R1 anti bait coimmunoprecipitation physical association 16477012 0.40 IntAct IRF8 Affinity Capture-Western physical 22262849 NA BioGRID ITGB3 Affinity Capture-Western physical 10964931 NA BioGRID KDR anti bait coimmunoprecipitation physical association 18997771 0.40 IntAct KLHL12 Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical, physical association 25416956, 0.70 BioGRID, IntAct KRTAP4-12 Two-hybrid, two hybrid pooling approach physical, physical association 16189514 0.37 BioGRID, IntAct LACC1 Affinity Capture-MS physical 28514442 NA BioGRID LAPTM4B anti tag coimmunoprecipitation physical association 25594178 0.40 IntAct LRP6 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical association 21245321 0.52 IntAct MFGE8 Affinity Capture-Western physical 21868707 NA BioGRID MYO1E Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct NCK1 Affinity Capture-Western, pull down association, physical 10026169, 1333047, 7692233 0.35 BioGRID, IntAct, MINT NCK2 Affinity Capture-Western, Reconstituted Complex, far western blotting physical, physical association 10026169, 11027258, 9737977 0.40 BioGRID, IntAct, MINT NEDD4 Biochemical Activity, Reconstituted Complex physical 19953087 NA BioGRID NOP9 Affinity Capture-MS physical 28514442 NA BioGRID NTRK1 Affinity Capture-MS physical 25921289 NA BioGRID PDCD6IP Affinity Capture-Western physical 17082185 NA BioGRID PDE3B Affinity Capture-MS physical 28514442 NA BioGRID PDGFA competition binding, enzyme linked immunosorbent assay physical association 7679113 0.52 IntAct PDGFB Affinity Capture-Western, Reconstituted Complex, competition binding, cross-linking study, enzyme linked immunosorbent assay, molecular sieving, x-ray crystallography direct interaction, physical, physical association 10806482, 11297552, 17981115, 20534510, 20577048, 7679113 0.90 BioGRID, IntAct PDGFC cross-linking study physical association 11297552 0.40 IntAct PDGFRA Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, enzyme linked immunosorbent assay physical, physical association 11331882, 2542288, 28514442, 7523122 0.40 BioGRID, IntAct PDGFRB Affinity Capture-Western, Far Western, comigration in sds page physical, physical association 11046132, 18505839, 7523122 0.40 BioGRID, IntAct PIK3C2B anti tag coimmunoprecipitation physical association 10805725 0.40 IntAct PIK3R1 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, biophysical, circular dichroism, classical fluorescence spectroscopy, coimmunoprecipitation, cross-linking study, isothermal titration calorimetry, nuclear magnetic resonance, proximity ligation assay, pull down, surface plasmon resonance, two hybrid association, physical, physical association 10697503, 10752619, 11710529, 11896612, 1314164, 1330535, 15377662, 16135792, 19864249, 28514442, 7536927, 7680644, 7692233, 8382612, 8564419, 8670861, 9153411 0.95 BioGRID, IntAct, MINT PIK3R2 biophysical association 1330535 0.35 IntAct, MINT PIK3R3 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct PLCG1 Affinity Capture-Western, Protein-peptide, coimmunoprecipitation, nuclear magnetic resonance, proximity ligation assay association, direct interaction, physical, physical association 11896612, 1396585, 15641795, 22974441, 23063561, 23397142, 8443409 0.82 BioGRID, IntAct, MINT PPM1L Two-hybrid physical 28065597 NA BioGRID PTEN Co-localization, filter binding, proximity ligation assay, pull down association, direct interaction, physical, physical association 16456542, 24012959, 25241761 0.70 BioGRID, IntAct, MINT PTPN1 affinity technology, anti tag coimmunoprecipitation, phosphatase assay dephosphorylation reaction, physical association 12614164, 19167335, 9355745 0.71 IntAct, MINT PTPN11 Reconstituted Complex, Two-hybrid, affinity technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, enzymatic study, experimental interaction detection, proximity ligation assay, surface plasmon resonance, x-ray crystallography association, physical, physical association 11266449, 12614164, 23397142, 7530043, 7688466, 7691811, 8119896, 8183548, 8538796 0.91 BioGRID, IntAct, MINT PTPN12 affinity technology, bimolecular fluorescence complementation, phosphatase assay dephosphorylation reaction, physical association 12614164, 19167335, 21376233 0.70 IntAct, MINT PTPN22 phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPN6 phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRB phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRC phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRE phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRG phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRJ biochemical, coimmunoprecipitation, phosphatase assay dephosphorylation reaction, physical association 10821867, 19167335 0.72 IntAct, MINT PTPRK phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRO phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRR phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct RAF1 Reconstituted Complex, proximity ligation assay physical, physical association 23397142, 2475255 0.40 BioGRID, IntAct RASA1 Affinity Capture-Western, coimmunoprecipitation association, physical 10697503, 11896619, 1314164, 1375321, 8382774 0.64 BioGRID, IntAct, MINT S1PR1 Affinity Capture-Western physical 12480944 NA BioGRID SH2B2 Affinity Capture-Western, pull down association, physical 9989826 0.35 BioGRID, IntAct, MINT SH3KBP1 Affinity Capture-Western physical 12177062 NA BioGRID SHC1 Affinity Capture-Western physical 8195171 NA BioGRID SLA Affinity Capture-Western, coimmunoprecipitation, pull down association, physical 18193084, 9742401 0.46 BioGRID, IntAct, MINT SLC9A3R1 Affinity Capture-Western, Far Western, Reconstituted Complex, filter binding, proximity ligation assay, pull down association, direct interaction, physical, physical association 11046132, 16456542, 23397142, 24012959 0.74 BioGRID, IntAct, MINT SLC9A3R2 filter binding direct interaction 16456542 0.44 IntAct, MINT SNX1 Affinity Capture-Western physical 9819414 NA BioGRID SNX2 Affinity Capture-Western physical 9819414 NA BioGRID SNX4 Affinity Capture-Western physical 9819414 NA BioGRID SRC Affinity Capture-Western, pull down association, physical 17158602, 17785434, 18315570, 7685273 0.35 BioGRID, IntAct, MINT STAT1 proximity ligation assay physical association 23397142 0.40 IntAct STAT3 Co-localization physical 25241761 NA BioGRID STAT3 proximity ligation assay physical association 25241761 0.40 IntAct STAT5A Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct TNK2 Affinity Capture-Western, Biochemical Activity physical 19815557, 25257795 NA BioGRID TPTE Two-hybrid physical 28065597 NA BioGRID TRIP6 Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical, physical association 25416956 0.56 BioGRID, IntAct TYW1 Affinity Capture-MS physical 28514442 NA BioGRID UBB Affinity Capture-MS physical 28514442 NA BioGRID VAV1 Affinity Capture-Western, Protein-peptide physical 10938113, 22974441 NA BioGRID VAV2 Affinity Capture-Western physical 10938113 NA BioGRID VAV3 Affinity Capture-Western physical 10938113 NA BioGRID VEGFA cross-linking study physical association 17470632 0.40 IntAct YES1 pull down association 7685273 0.35 IntAct, MINT ZZEF1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct