Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ACTB molecular sieving physical association 15047060 0.40 IntAct ADAM15 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, pull down physical, physical association 11741929, 16374509 0.52 BioGRID, IntAct, MINT AR fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct BCL3 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down physical association 16099425 0.59 IntAct, MINT CBL Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, pull down direct interaction, physical, physical association 11904433, 16107303, 7721825, 8621719, 8626543, 8900205 0.75 BioGRID, IntAct, MINT CD2 Affinity Capture-Western, Reconstituted Complex, experimental interaction detection phosphorylation reaction, physical 8551220, 9677430 0.31 BioGRID, IntAct, MINT CD247 Affinity Capture-Western, protein kinase assay, pull down phosphorylation reaction, physical, physical association 14523017, 16461343, 24463463, 26390156, 8626561 0.44, 0.61 BioGRID, IntAct, MINT CD3E Affinity Capture-Western, pull down association, physical 11855827, 14523017 0.35 BioGRID, IntAct, MINT CD4 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, anti bait coimmunoprecipitation physical, physical association 11854499, 12007789, 15047060, 16888650, 17005671, 17653867, 8246987 0.70 BioGRID, IntAct, MINT CD55 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct CDC42 protein kinase assay phosphorylation reaction 16293614 0.44 IntAct CDKAL1 Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical, physical association 25416956 0.56 BioGRID, IntAct CSNK2B Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT DLG1 anti bait coimmunoprecipitation, proximity ligation assay, pull down physical association 25241761, 9341123 0.66 IntAct, MINT DOK2 Two-hybrid, two hybrid array, validated two hybrid physical, physical association 25814554 0.49 BioGRID, IntAct FAS Reconstituted Complex, anti bait coimmunoprecipitation association, physical 20696918, 8864141 0.35 BioGRID, IntAct G3BP1 Biochemical Activity, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical, physical association 15743820 0.52 BioGRID, IntAct, MINT GAB1 fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct GATA3 two hybrid array, two hybrid prey pooling approach, validated two hybrid physical association 26871637 0.56 IntAct GRB2 protein kinase assay phosphorylation reaction 23460737 0.44 IntAct HAVCR2 Affinity Capture-Western, anti bait coimmunoprecipitation, pull down association, physical 22863785, 26492563 0.46 BioGRID, IntAct HSP90AA1 Affinity Capture-Luminescence, Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 16888650, 22939624 0.40 BioGRID, IntAct, MINT HSP90AB1 anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping physical association 22939624 0.52 IntAct IKBKG Reconstituted Complex, protein array direct interaction, physical 20098747 0.44 BioGRID, IntAct KHDRBS1 anti bait coimmunoprecipitation, coimmunoprecipitation, pull down physical association 11278465, 16107303, 16888650, 7852312, 9045636 0.83 IntAct, MINT KIT Affinity Capture-Western, fluorescence polarization spectroscopy direct interaction, physical 24728074, 9788619 0.44 BioGRID, IntAct LAT Affinity Capture-Western, Biochemical Activity, Co-fractionation, anti bait coimmunoprecipitation, protein kinase assay association, phosphorylation reaction, physical 14523017, 16938345 0.52 BioGRID, IntAct LCK Biochemical Activity, cosedimentation in solution, fluorescence technology, protein kinase assay, x-ray crystallography direct interaction, phosphorylation reaction, physical 17118402, 20372794, 24463463 0.72 BioGRID, IntAct, MINT LCP2 anti tag coimmunoprecipitation, far western blotting association, physical association 10556826, 21725281 0.56 IntAct, MINT LYN anti bait coimmunoprecipitation association 18070987 0.35 IntAct, MINT LZTS2 two hybrid array, two hybrid prey pooling approach, validated two hybrid physical association 25416956 0.56 IntAct MAPK1 Biochemical Activity, anti bait coimmunoprecipitation, pull down physical, physical association 15967991, 8626561 0.52 BioGRID, IntAct, MINT MED25 classical fluorescence spectroscopy direct interaction 19290556 0.44 IntAct, MINT MED28 anti bait coimmunoprecipitation, protein kinase assay, pull down, two hybrid association, phosphorylation reaction, physical association 10656681, 16899217 0.69 IntAct MET fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct NR3C1 Affinity Capture-Western, anti bait coimmunoprecipitation, imaging technique colocalization, physical, physical association 16888650 0.46 BioGRID, IntAct, MINT PAG1 Reconstituted Complex, anti bait coimmunoprecipitation association, physical 10790433, 18070987 0.35 BioGRID, IntAct, MINT PIK3R1 Reconstituted Complex, pull down physical, physical association 8246987, 8294442 0.40 BioGRID, IntAct, MINT PRKCQ Two-hybrid, anti tag coimmunoprecipitation association, physical, physical association 10383400, 21964608 0.50 BioGRID, IntAct PTPN12 phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPN22 Affinity Capture-MS, Affinity Capture-Western, phosphatase assay, pull down association, dephosphorylation reaction, direct interaction, physical 16461343, 19167335, 21719704 0.78 BioGRID, IntAct PTPN6 Biochemical Activity, Reconstituted Complex, phosphatase assay, protein kinase assay dephosphorylation reaction, phosphorylation reaction, physical 10617656, 11294838, 19167335, 8114715 0.62 BioGRID, IntAct, MINT PTPRB phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRC affinity chromatography technology, anti bait coimmunoprecipitation, phosphatase assay, protein kinase assay, protein phosphatase assay, pull down dephosphorylation reaction, direct interaction, phosphorylation reaction, physical association 10369126, 19167335, 24463463, 7507203, 8576115 0.44, 0.85 IntAct, MINT PTPRG phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRJ phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRK phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRM phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRO phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRZ1 phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct RIN3 Two-hybrid, two hybrid array physical, physical association 25814554 0.37 BioGRID, IntAct SH2D1A anti bait coimmunoprecipitation, two hybrid association, physical association 15096483, 24688028 0.55 IntAct, MINT SH2D2A anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, pull down physical association 10553045, 15827961, 16839418 0.77 IntAct, MINT SH3BP2 pull down association 15751964 0.35 IntAct, MINT SLAMF6 anti bait coimmunoprecipitation association, physical association 24688028 0.35, 0.40 IntAct STAT3 anti bait coimmunoprecipitation, two hybrid array, validated two hybrid association, physical association 18070987, 25814554 0.35, 0.49 IntAct, MINT SYK Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, pull down, two hybrid association, physical, physical association 15536084, 7539035, 8621719, 8798676 0.75 BioGRID, IntAct, MINT THEMIS protein kinase assay, pull down association, phosphorylation reaction 23460737 0.52 IntAct UBC Co-crystal Structure, Protein-peptide, nuclear magnetic resonance, pull down direct interaction, physical, physical association 18539162 0.54 BioGRID, IntAct, MINT UHRF2 Far Western, antibody array physical, physical association 21952639 0.40 BioGRID, IntAct VAV1 pull down association 17050525 0.35 IntAct, MINT WAS Affinity Capture-Western, Biochemical Activity, pull down physical, physical association 16107303, 16293614 0.40 BioGRID, IntAct, MINT WASL Biochemical Activity, protein kinase assay phosphorylation reaction, physical 16293614 0.44 BioGRID, IntAct ZAP70 Affinity Capture-Western, anti tag coimmunoprecipitation, far western blotting, protein kinase assay association, phosphorylation reaction, physical, physical association 10318843, 10556826, 16461343, 7539035, 8798643 0.70 BioGRID, IntAct, MINT