Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
LCK	6524	COSM5751804,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A117S	Substitution - Missense	1:32275391-32275391,	PATHOGENIC	0.99796	26206799
LCK	6524	COSM1602214,	liver	carcinoma	p.L247Q	Substitution - Missense	1:32276445-32276445,	PATHOGENIC	0.99771	Info_not_available
LCK	6524	COSM1645497,	large_intestine	carcinoma	p.A396V	Substitution - Missense	1:32279986-32279986,	PATHOGENIC	0.99509	23700467
LCK	6524	COSM94600,	lung	carcinoma	p.R363H	Substitution - Missense	1:32279887-32279887,	PATHOGENIC	0.98969	20668451
LCK	6524	COSM4990563,	skin	carcinoma	p.G85R	Substitution - Missense	1:32275058-32275058,	PATHOGENIC	0.9893	25589618
LCK	6524	COSM327041,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P447L	Substitution - Missense	1:32285526-32285526,	PATHOGENIC	0.98828	22675565
LCK	6524	COSM327043,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A500T	Substitution - Missense	1:32285684-32285684,	PATHOGENIC	0.98624	22675565
LCK	6524	COSM4990566,	skin	carcinoma	p.G85E	Substitution - Missense	1:32275059-32275059,	PATHOGENIC	0.98436	25589618
LCK	6524	COSM327039,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A353V	Substitution - Missense	1:32279857-32279857,	PATHOGENIC	0.98111	22675565
LCK	6524	COSM327047,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y360H	Substitution - Missense	1:32279877-32279877,	PATHOGENIC	0.97959	22675565
LCK	6524	COSM95623,	lung	carcinoma	p.Q508*	Substitution - Nonsense	1:32285708-32285708,	PATHOGENIC	0.92673	20668451
LCK	6524	COSM13333,	central_nervous_system	glioma	p.K269K	Substitution - coding silent	1:32276629-32276629,	PATHOGENIC	0.81711	16618716
LCK	6524	COSM13333,	central_nervous_system	glioma	p.K269K	Substitution - coding silent	1:32276629-32276629,	PATHOGENIC	0.81711	16618716
LCK	6524	COSM327045,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	1:32275428-32275428,	NEUTRAL	0.09291	22675565
LCK	6524	COSM48482,	lung	carcinoma	p.P331S	Substitution - Missense	1:32279697-32279697,	NEUTRAL	0.01904	18948947
LCK	6524	COSM1213171,	stomach	carcinoma	p.R387C	Substitution - Missense	1:32279958-32279958,	Info_not_available	0.65832	26489445