Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ACTB molecular sieving physical association 15047060 0.40 IntAct ADAM10 Affinity Capture-Western physical 11741929 NA BioGRID ADAM15 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, pull down physical, physical association 11741929, 16374509 0.52 BioGRID, IntAct, MINT AJUBA Two-hybrid physical 15870274 NA BioGRID AR fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct ARHGAP17 Reconstituted Complex physical 11431473 NA BioGRID AXL Far Western physical 9178760 NA BioGRID BAG6 Affinity Capture-Western physical 22863785 NA BioGRID BCAR1 Reconstituted Complex physical 9020138 NA BioGRID BCL3 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down physical association 16099425 0.59 IntAct, MINT BRCA1 Two-hybrid physical 25184681 NA BioGRID CBL Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, pull down direct interaction, physical, physical association 11904433, 16107303, 7721825, 8621719, 8626543, 8900205 0.75 BioGRID, IntAct, MINT CBLB Affinity Capture-Western physical 21453975 NA BioGRID CD2 Affinity Capture-Western, Reconstituted Complex, experimental interaction detection phosphorylation reaction, physical 8551220, 9677430 0.31 BioGRID, IntAct, MINT CD247 Affinity Capture-Western, protein kinase assay, pull down phosphorylation reaction, physical, physical association 14523017, 16461343, 24463463, 26390156, 8626561 0.44, 0.61 BioGRID, IntAct, MINT CD38 Affinity Capture-Western physical 14523017 NA BioGRID CD3E Affinity Capture-Western, pull down association, physical 11855827, 14523017 0.35 BioGRID, IntAct, MINT CD4 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, anti bait coimmunoprecipitation physical, physical association 11854499, 12007789, 15047060, 16888650, 17005671, 17653867, 8246987 0.70 BioGRID, IntAct, MINT CD44 Affinity Capture-Western, Co-fractionation physical 8576267, 9573028 NA BioGRID CD48 Affinity Capture-Western physical 12007789 NA BioGRID CD5 Affinity Capture-Western physical 21757751 NA BioGRID CD55 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct CDC42 protein kinase assay phosphorylation reaction 16293614 0.44 IntAct CDKAL1 Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical, physical association 25416956 0.56 BioGRID, IntAct CISH Affinity Capture-Western physical 21234523 NA BioGRID CSNK2B Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT CTLA4 Affinity Capture-Western physical 9712716 NA BioGRID CTNND1 Biochemical Activity physical 12835311 NA BioGRID DLG1 Affinity Capture-Western, Co-localization, Reconstituted Complex physical 25241761, 9341123 NA BioGRID DLG1 anti bait coimmunoprecipitation, proximity ligation assay, pull down physical association 25241761, 9341123 0.66 IntAct, MINT DOK2 Two-hybrid, two hybrid array, validated two hybrid physical, physical association 25814554 0.49 BioGRID, IntAct FAM174A Protein-peptide physical 16274251 NA BioGRID FAS Reconstituted Complex, anti bait coimmunoprecipitation association, physical 20696918, 8864141 0.35 BioGRID, IntAct FASLG Reconstituted Complex physical 11741599 NA BioGRID G3BP1 Biochemical Activity, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical, physical association 15743820 0.52 BioGRID, IntAct, MINT GAB1 fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct GATA3 two hybrid array, two hybrid prey pooling approach, validated two hybrid physical association 26871637 0.56 IntAct GRB2 protein kinase assay phosphorylation reaction 23460737 0.44 IntAct HAVCR2 Affinity Capture-Western, anti bait coimmunoprecipitation, pull down association, physical 22863785, 26492563 0.46 BioGRID, IntAct HSP90AA1 Affinity Capture-Luminescence, Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 16888650, 22939624 0.40 BioGRID, IntAct, MINT HSP90AB1 anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping physical association 22939624 0.52 IntAct IKBKG Reconstituted Complex, protein array direct interaction, physical 20098747 0.44 BioGRID, IntAct IL2RB Affinity Capture-Western physical 21834013 NA BioGRID KHDRBS1 Affinity Capture-Western, Protein-peptide physical 16107303, 16274251, 16888650, 9045636 NA BioGRID KHDRBS1 anti bait coimmunoprecipitation, coimmunoprecipitation, pull down physical association 11278465, 16107303, 16888650, 7852312, 9045636 0.83 IntAct, MINT KIT Affinity Capture-Western, fluorescence polarization spectroscopy direct interaction, physical 24728074, 9788619 0.44 BioGRID, IntAct LAT Affinity Capture-Western, Biochemical Activity, Co-fractionation, anti bait coimmunoprecipitation, protein kinase assay association, phosphorylation reaction, physical 14523017, 16938345 0.52 BioGRID, IntAct LCK Biochemical Activity, cosedimentation in solution, fluorescence technology, protein kinase assay, x-ray crystallography direct interaction, phosphorylation reaction, physical 17118402, 20372794, 24463463 0.72 BioGRID, IntAct, MINT LCP2 anti tag coimmunoprecipitation, far western blotting association, physical association 10556826, 21725281 0.56 IntAct, MINT LYN anti bait coimmunoprecipitation association 18070987 0.35 IntAct, MINT LZTS2 Two-hybrid physical 25416956 NA BioGRID LZTS2 two hybrid array, two hybrid prey pooling approach, validated two hybrid physical association 25416956 0.56 IntAct MAPK1 Biochemical Activity, anti bait coimmunoprecipitation, pull down physical, physical association 15967991, 8626561 0.52 BioGRID, IntAct, MINT MED25 classical fluorescence spectroscopy direct interaction 19290556 0.44 IntAct, MINT MED28 anti bait coimmunoprecipitation, protein kinase assay, pull down, two hybrid association, phosphorylation reaction, physical association 10656681, 16899217 0.69 IntAct MET fluorescence polarization spectroscopy direct interaction 24728074 0.44 IntAct MS4A1 Affinity Capture-Western physical 7545683 NA BioGRID NEDD9 Affinity Capture-Western physical 8879209 NA BioGRID NOTCH1 Affinity Capture-Western physical 14583609 NA BioGRID NR3C1 Affinity Capture-Western, anti bait coimmunoprecipitation, imaging technique colocalization, physical, physical association 16888650 0.46 BioGRID, IntAct, MINT PAG1 Reconstituted Complex, anti bait coimmunoprecipitation association, physical 10790433, 18070987 0.35 BioGRID, IntAct, MINT PAK2 Reconstituted Complex physical 16374509 NA BioGRID PECAM1 Biochemical Activity physical 9624175 NA BioGRID PI4KA Reconstituted Complex physical 8246987 NA BioGRID PIK3CA Affinity Capture-Western, Reconstituted Complex physical 14583609, 8246987 NA BioGRID PIK3R1 Reconstituted Complex, pull down physical, physical association 8246987, 8294442 0.40 BioGRID, IntAct, MINT PRKCQ Two-hybrid, anti tag coimmunoprecipitation association, physical, physical association 10383400, 21964608 0.50 BioGRID, IntAct PTK2B Affinity Capture-Western physical 9091579 NA BioGRID PTPN12 phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPN22 Affinity Capture-MS, Affinity Capture-Western, phosphatase assay, pull down association, dephosphorylation reaction, direct interaction, physical 16461343, 19167335, 21719704 0.78 BioGRID, IntAct PTPN6 Biochemical Activity, Reconstituted Complex, phosphatase assay, protein kinase assay dephosphorylation reaction, phosphorylation reaction, physical 10617656, 11294838, 19167335, 8114715 0.62 BioGRID, IntAct, MINT PTPRB phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRC Affinity Capture-Western, Reconstituted Complex physical 15085197, 8473339, 8576115 NA BioGRID PTPRC affinity chromatography technology, anti bait coimmunoprecipitation, phosphatase assay, protein kinase assay, protein phosphatase assay, pull down dephosphorylation reaction, direct interaction, phosphorylation reaction, physical association 10369126, 19167335, 24463463, 7507203, 8576115 0.44, 0.85 IntAct, MINT PTPRG phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRJ phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRK phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRM phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRO phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRZ1 phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PXN Affinity Capture-Western physical 9488700 NA BioGRID RAF1 Affinity Capture-Western physical 8939988 NA BioGRID RASA1 Biochemical Activity physical 11389730 NA BioGRID RIN3 Two-hybrid, two hybrid array physical, physical association 25814554 0.37 BioGRID, IntAct SH2B3 Affinity Capture-Western physical 10799879 NA BioGRID SH2D1A anti bait coimmunoprecipitation, two hybrid association, physical association 15096483, 24688028 0.55 IntAct, MINT SH2D2A anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, pull down physical association 10553045, 15827961, 16839418 0.77 IntAct, MINT SH3BP2 pull down association 15751964 0.35 IntAct, MINT SH3KBP1 Affinity Capture-Western physical 15707590 NA BioGRID SIT1 Affinity Capture-Western physical 10209036 NA BioGRID SKAP1 Affinity Capture-Western, Reconstituted Complex physical 10229084, 9195899 NA BioGRID SLAMF6 anti bait coimmunoprecipitation association, physical association 24688028 0.35, 0.40 IntAct SMAD2 Reconstituted Complex physical 16806069 NA BioGRID SMAD3 Reconstituted Complex physical 16806069 NA BioGRID SMURF1 Biochemical Activity physical 20804422 NA BioGRID SOCS1 Affinity Capture-Western physical 21234523 NA BioGRID SOCS2 Affinity Capture-Western physical 21234523 NA BioGRID SOCS3 Affinity Capture-Western physical 21234523 NA BioGRID SOS1 Protein-peptide physical 16274251 NA BioGRID SQSTM1 Reconstituted Complex physical 8650207 NA BioGRID STAT3 Two-hybrid physical 25814554 NA BioGRID STAT3 anti bait coimmunoprecipitation, two hybrid array, validated two hybrid association, physical association 18070987, 25814554 0.35, 0.49 IntAct, MINT SYK Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, pull down, two hybrid association, physical, physical association 15536084, 7539035, 8621719, 8798676 0.75 BioGRID, IntAct, MINT THEMIS protein kinase assay, pull down association, phosphorylation reaction 23460737 0.52 IntAct THY1 Affinity Capture-Western physical 1351058 NA BioGRID TRAT1 Reconstituted Complex physical 10790433 NA BioGRID TRPV4 Affinity Capture-Western physical 12538589 NA BioGRID UBC Co-crystal Structure, Protein-peptide, nuclear magnetic resonance, pull down direct interaction, physical, physical association 18539162 0.54 BioGRID, IntAct, MINT UBE3A Reconstituted Complex, Two-hybrid physical 10449731 NA BioGRID UHRF2 Far Western, antibody array physical, physical association 21952639 0.40 BioGRID, IntAct UNC119 Affinity Capture-Western, Reconstituted Complex physical 14757743 NA BioGRID VAV1 pull down association 17050525 0.35 IntAct, MINT WAS Affinity Capture-Western, Biochemical Activity, pull down physical, physical association 16107303, 16293614 0.40 BioGRID, IntAct, MINT WASL Biochemical Activity, protein kinase assay phosphorylation reaction, physical 16293614 0.44 BioGRID, IntAct YWHAQ Affinity Capture-Western physical 19010391 NA BioGRID ZAP70 Affinity Capture-Western, anti tag coimmunoprecipitation, far western blotting, protein kinase assay association, phosphorylation reaction, physical, physical association 10318843, 10556826, 16461343, 7539035, 8798643 0.70 BioGRID, IntAct, MINT