Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
KDR	6307	COSM6918918,	prostate	carcinoma	p.?	Unknown	4:55095575-55095575,	PATHOGENIC	0.99866	28481359
KDR	6307	COSM6964865,	lung	carcinoma	p.K939E	Substitution - Missense	4:55095579-55095579,	PATHOGENIC	0.99818	28481359
KDR	6307	COSM5731164,	small_intestine	carcinoma	p.S1154L	Substitution - Missense	4:55088917-55088917,	PATHOGENIC	0.99799	26315110
KDR	6307	COSM6947457,	oesophagus	carcinoma	p.?	Unknown	4:55088866-55088866,	PATHOGENIC	0.99793	28481359
KDR	6307	COSM6924473,	genital_tract	germ_cell_tumour	p.Q1257K	Substitution - Missense	4:55082035-55082035,	PATHOGENIC	0.99776	28481359
KDR	6307	COSM6916167,	ovary	sex_cord-stromal_tumour	p.W458G	Substitution - Missense	4:55107777-55107777,	PATHOGENIC	0.99768	28481359
KDR	6307	COSM6985018,	lung	carcinoma	p.G756S	Substitution - Missense	4:55101897-55101897,	PATHOGENIC	0.99752	28481359
KDR	6307	COSM6946587,	urinary_tract	carcinoma	p.T446M	Substitution - Missense	4:55107812-55107812,	PATHOGENIC	0.99724	28481359
KDR	6307	COSM6919067,	lung	carcinoma	p.L797Q	Substitution - Missense	4:55098256-55098256,	PATHOGENIC	0.99717	28481359
KDR	6307	COSM3301522,	skin	malignant_melanoma	p.G1161E	Substitution - Missense	4:55088896-55088896,	PATHOGENIC	0.99707	28481359
KDR	6307	COSM3301522,	central_nervous_system	glioma	p.G1161E	Substitution - Missense	4:55088896-55088896,	PATHOGENIC	0.99707	28481359
KDR	6307	COSM5609234,	skin	malignant_melanoma	p.L797P	Substitution - Missense	4:55098256-55098256,	PATHOGENIC	0.997	26343386
KDR	6307	COSM5518530,	skin	malignant_melanoma	p.G438S	Substitution - Missense	4:55107837-55107837,	PATHOGENIC	0.99687	28481359
KDR	6307	COSM1430208,	endometrium	carcinoma	p.R1022Q	Substitution - Missense	4:55092621-55092621,	PATHOGENIC	0.99679	28481359
KDR	6307	COSM1430208,	urinary_tract	carcinoma	p.R1022Q	Substitution - Missense	4:55092621-55092621,	PATHOGENIC	0.99679	28481359
KDR	6307	COSM6966001,	genital_tract	germ_cell_tumour	p.K790Q	Substitution - Missense	4:55098702-55098702,	PATHOGENIC	0.99657	28481359
KDR	6307	COSM6966298,	kidney	carcinoma	p.S515G	Substitution - Missense	4:55105934-55105934,	PATHOGENIC	0.99649	28481359
KDR	6307	COSM95713,	lung	carcinoma	p.?	Unknown	4:55107894-55107894,	PATHOGENIC	0.99639	20668451
KDR	6307	COSM6922745,	kidney	carcinoma	p.T397S	Substitution - Missense	4:55110468-55110468,	PATHOGENIC	0.99609	28481359
KDR	6307	COSM232599,	skin	malignant_melanoma	p.D1259N	Substitution - Missense	4:55082029-55082029,	PATHOGENIC	0.99605	26343386
KDR	6307	COSM1671032,	prostate	carcinoma	p.C466F	Substitution - Missense	4:55107752-55107752,	PATHOGENIC	0.99605	20579941
KDR	6307	COSM6922378,	skin	malignant_melanoma	p.P64S	Substitution - Missense	4:55118772-55118772,	PATHOGENIC	0.99563	28481359
KDR	6307	COSM4992135,	skin	carcinoma	p.?	Unknown	4:55102029-55102029,	PATHOGENIC	0.99556	25589618
KDR	6307	COSM6950683,	lung	carcinoma	p.?	Unknown	4:55107736-55107736,	PATHOGENIC	0.99547	28481359
KDR	6307	COSM4342358,	lung	carcinoma	p.G638E	Substitution - Missense	4:55104717-55104717,	PATHOGENIC	0.99525	28481359
KDR	6307	COSM6956738,	upper_aerodigestive_tract	carcinoma	p.T864R	Substitution - Missense	4:55097685-55097685,	PATHOGENIC	0.99515	28481359
KDR	6307	COSM6948969,	large_intestine	carcinoma	p.L924P	Substitution - Missense	4:55095623-55095623,	PATHOGENIC	0.99483	28481359
KDR	6307	COSM5046925,	oesophagus	carcinoma	p.A874E	Substitution - Missense	4:55096336-55096336,	PATHOGENIC	0.99468	24686850
KDR	6307	COSM5731104,	breast	other	p.A775V	Substitution - Missense	4:55098746-55098746,	PATHOGENIC	0.99462	26832993
KDR	6307	COSM3604565,	skin	malignant_melanoma	p.P351S	Substitution - Missense	4:55110694-55110694,	PATHOGENIC	0.99462	28481359
KDR	6307	COSM3604565,	skin	malignant_melanoma	p.P351S	Substitution - Missense	4:55110694-55110694,	PATHOGENIC	0.99462	28481359
KDR	6307	COSM6967040,	lung	carcinoma	p.?	Unknown	4:55081954-55081954,	PATHOGENIC	0.99455	28481359
KDR	6307	COSM6909961,	lung	carcinoma	p.P1105T	Substitution - Missense	4:55089465-55089465,	PATHOGENIC	0.99437	28481359
KDR	6307	COSM4427478,	lung	carcinoma	p.D574H	Substitution - Missense	4:55104910-55104910,	PATHOGENIC	0.99421	28481359
KDR	6307	COSM5401331,	skin	malignant_melanoma	p.G55R	Substitution - Missense	4:55118799-55118799,	PATHOGENIC	0.99414	28481359
KDR	6307	COSM94564,	lung	carcinoma	p.H816Y	Substitution - Missense	4:55098200-55098200,	PATHOGENIC	0.99411	20668451
KDR	6307	COSM6941129,	NS	carcinoma	p.I754R	Substitution - Missense	4:55101902-55101902,	PATHOGENIC	0.99402	28481359
KDR	6307	COSM6941129,	NS	carcinoma	p.I754R	Substitution - Missense	4:55101902-55101902,	PATHOGENIC	0.99402	28481359
KDR	6307	COSM6931687,	central_nervous_system	glioma	p.C1142Y	Substitution - Missense	4:55088953-55088953,	PATHOGENIC	0.99397	28481359
KDR	6307	COSM6964001,	breast	carcinoma	p.P696T	Substitution - Missense	4:55102410-55102410,	PATHOGENIC	0.99396	28481359
KDR	6307	COSM6927605,	central_nervous_system	glioma	p.R664C	Substitution - Missense	4:55102506-55102506,	PATHOGENIC	0.9939	28481359
KDR	6307	COSM6956265,	large_intestine	carcinoma	p.G744C	Substitution - Missense	4:55101933-55101933,	PATHOGENIC	0.99363	28481359
KDR	6307	COSM6923604,	large_intestine	carcinoma	p.P166S	Substitution - Missense	4:55115036-55115036,	PATHOGENIC	0.99345	28481359
KDR	6307	COSM6922798,	NS	malignant_melanoma	p.P1105S	Substitution - Missense	4:55089465-55089465,	PATHOGENIC	0.99342	28481359
KDR	6307	COSM6959057,	lung	carcinoma	p.L896F	Substitution - Missense	4:55096271-55096271,	PATHOGENIC	0.99337	28481359
KDR	6307	COSM6917176,	skin	malignant_melanoma	p.?	Unknown	4:55082042-55082042,	PATHOGENIC	0.99332	28481359
KDR	6307	COSM3917939,	skin	malignant_melanoma	p.G394E	Substitution - Missense	4:55110477-55110477,	PATHOGENIC	0.99309	28481359
KDR	6307	COSM1430209,	endometrium	carcinoma	p.G1015D	Substitution - Missense	4:55092642-55092642,	PATHOGENIC	0.99304	28481359
KDR	6307	COSM4992128,	skin	carcinoma	p.M1016I	Substitution - Missense	4:55092638-55092638,	PATHOGENIC	0.99304	25589618
KDR	6307	COSM6966115,	skin	malignant_melanoma	p.P694S	Substitution - Missense	4:55102416-55102416,	PATHOGENIC	0.99293	28481359
KDR	6307	COSM4992137,	skin	carcinoma	p.P694L	Substitution - Missense	4:55102415-55102415,	PATHOGENIC	0.99292	25589618
KDR	6307	COSM3940903,	skin	carcinoma	p.A775S	Substitution - Missense	4:55098747-55098747,	PATHOGENIC	0.9928	25589618
KDR	6307	COSM6969204,	lung	carcinoma	p.?	Unknown	4:55095667-55095667,	PATHOGENIC	0.99208	28481359
KDR	6307	COSM6952034,	large_intestine	carcinoma	p.E463V	Substitution - Missense	4:55107761-55107761,	PATHOGENIC	0.99206	28481359
KDR	6307	COSM1211807,	skin	carcinoma	p.S1037L	Substitution - Missense	4:55090038-55090038,	PATHOGENIC	0.99191	28481359
KDR	6307	COSM1211807,	skin	malignant_melanoma	p.S1037L	Substitution - Missense	4:55090038-55090038,	PATHOGENIC	0.99191	28481359
KDR	6307	COSM6986322,	lung	carcinoma	p.A1103S	Substitution - Missense	4:55089471-55089471,	PATHOGENIC	0.99163	28481359
KDR	6307	COSM6955572,	urinary_tract	carcinoma	p.R1126K	Substitution - Missense	4:55089401-55089401,	PATHOGENIC	0.99142	28481359
KDR	6307	COSM3604539,	skin	malignant_melanoma	p.S1100F	Substitution - Missense	4:55089696-55089696,	PATHOGENIC	0.99136	28481359
KDR	6307	COSM3604539,	skin	carcinoma	p.S1100F	Substitution - Missense	4:55089696-55089696,	PATHOGENIC	0.99136	25589618
KDR	6307	COSM6949351,	stomach	carcinoma	p.L1035I	Substitution - Missense	4:55090045-55090045,	PATHOGENIC	0.99114	28481359
KDR	6307	COSM6934201,	soft_tissue	angiosarcoma	p.T771R	Substitution - Missense	4:55098758-55098758,	PATHOGENIC	0.99093	28481359
KDR	6307	COSM4381082,	soft_tissue	angiosarcoma	p.T771K	Substitution - Missense	4:55098758-55098758,	PATHOGENIC	0.99057	25252913
KDR	6307	COSM6956169,	lung	carcinoma	p.G550C	Substitution - Missense	4:55104982-55104982,	PATHOGENIC	0.99048	28481359
KDR	6307	COSM7325452,	biliary_tract	carcinoma	p.E878A	Substitution - Missense	4:55096324-55096324,	PATHOGENIC	0.99043	29360550
KDR	6307	COSM6919951,	small_intestine	carcinoma	p.D832V	Substitution - Missense	4:55098151-55098151,	PATHOGENIC	0.99017	28481359
KDR	6307	COSM6966445,	skin	carcinoma	p.L292S	Substitution - Missense	4:55113405-55113405,	PATHOGENIC	0.98972	28481359
KDR	6307	COSM6956939,	skin	carcinoma	p.G1102D	Substitution - Missense	4:55089473-55089473,	PATHOGENIC	0.98964	28481359
KDR	6307	COSM3301527,	endometrium	carcinoma	p.R1118Q	Substitution - Missense	4:55089425-55089425,	PATHOGENIC	0.98964	28481359
KDR	6307	COSM6944046,	skin	carcinoma	p.?	Unknown	4:55097767-55097767,	PATHOGENIC	0.98952	28481359
KDR	6307	COSM32294,	large_intestine	carcinoma	p.G873R	Substitution - Missense	4:55096340-55096340,	PATHOGENIC	0.98931	16959974
KDR	6307	COSM6974658,	large_intestine	carcinoma	p.I1044T	Substitution - Missense	4:55090017-55090017,	PATHOGENIC	0.9893	28481359
KDR	6307	COSM6980634,	large_intestine	carcinoma	p.?	Unknown	4:55115412-55115412,	PATHOGENIC	0.98921	28481359
KDR	6307	COSM4992136,	skin	carcinoma	p.W700*	Substitution - Nonsense	4:55102397-55102397,	PATHOGENIC	0.98886	25589618
KDR	6307	COSM6925212,	lung	carcinoma	p.P830T	Substitution - Missense	4:55098158-55098158,	PATHOGENIC	0.9888	28481359
KDR	6307	COSM94566,	lung	carcinoma	p.T771M	Substitution - Missense	4:55098758-55098758,	PATHOGENIC	0.98833	20668451
KDR	6307	COSM94566,	large_intestine	carcinoma	p.T771M	Substitution - Missense	4:55098758-55098758,	PATHOGENIC	0.98833	28481359
KDR	6307	COSM5020657,	soft_tissue	haemangioblastoma	p.C482R	Substitution - Missense	4:55106779-55106779,	PATHOGENIC	0.98809	25589003
KDR	6307	COSM6930866,	lung	carcinoma	p.V898M	Substitution - Missense	4:55096265-55096265,	PATHOGENIC	0.98806	28481359
KDR	6307	COSM6963464,	skin	carcinoma	p.G99V	Substitution - Missense	4:55118666-55118666,	PATHOGENIC	0.98799	28481359
KDR	6307	COSM3301592,	skin	carcinoma	p.P230L	Substitution - Missense	4:55114235-55114235,	PATHOGENIC	0.98765	28481359
KDR	6307	COSM3301592,	large_intestine	carcinoma	p.P230L	Substitution - Missense	4:55114235-55114235,	PATHOGENIC	0.98765	28481359
KDR	6307	COSM6949109,	skin	carcinoma	p.P453S	Substitution - Missense	4:55107792-55107792,	PATHOGENIC	0.98711	28481359
KDR	6307	COSM6904710,	pancreas	carcinoma	p.T1152M	Substitution - Missense	4:55088923-55088923,	PATHOGENIC	0.98644	28481359
KDR	6307	COSM6967032,	soft_tissue	liposarcoma	p.D433Y	Substitution - Missense	4:55107852-55107852,	PATHOGENIC	0.98641	28481359
KDR	6307	COSM6963054,	lung	carcinoma	p.N96I	Substitution - Missense	4:55118675-55118675,	PATHOGENIC	0.98621	28481359
KDR	6307	COSM6006367,	NS	malignant_melanoma	p.G976R	Substitution - Missense	4:55094847-55094847,	PATHOGENIC	0.9862	25148578
KDR	6307	COSM6955971,	lung	carcinoma	p.L161I	Substitution - Missense	4:55115289-55115289,	PATHOGENIC	0.98601	28481359
KDR	6307	COSM192176,	skin	malignant_melanoma	p.R1032Q	Substitution - Missense	4:55090053-55090053,	PATHOGENIC	0.98575	28481359
KDR	6307	COSM192176,	skin	malignant_melanoma	p.R1032Q	Substitution - Missense	4:55090053-55090053,	PATHOGENIC	0.98575	26343386
KDR	6307	COSM192176,	skin	malignant_melanoma	p.R1032Q	Substitution - Missense	4:55090053-55090053,	PATHOGENIC	0.98575	26343386
KDR	6307	COSM192176,	endometrium	carcinoma	p.R1032Q	Substitution - Missense	4:55090053-55090053,	PATHOGENIC	0.98575	28481359
KDR	6307	COSM192176,	skin	malignant_melanoma	p.R1032Q	Substitution - Missense	4:55090053-55090053,	PATHOGENIC	0.98575	26343386
KDR	6307	COSM192176,	NS	malignant_melanoma	p.R1032Q	Substitution - Missense	4:55090053-55090053,	PATHOGENIC	0.98575	28481359
KDR	6307	COSM6943862,	lung	carcinoma	p.E326*	Substitution - Nonsense	4:55113304-55113304,	PATHOGENIC	0.98574	28481359
KDR	6307	COSM6986067,	soft_tissue	gastrointestinal_stromal_tumour	p.T1138S	Substitution - Missense	4:55088965-55088965,	PATHOGENIC	0.98409	28481359
KDR	6307	COSM6944379,	lung	carcinoma	p.G1048V	Substitution - Missense	4:55090005-55090005,	PATHOGENIC	0.98398	28481359
KDR	6307	COSM3604541,	skin	malignant_melanoma	p.G1063E	Substitution - Missense	4:55089960-55089960,	PATHOGENIC	0.98387	28481359
KDR	6307	COSM3604542,	lung	carcinoma	p.D1056N	Substitution - Missense	4:55089982-55089982,	PATHOGENIC	0.98387	28481359
KDR	6307	COSM6005667,	prostate	carcinoma	p.A1065T	Substitution - Missense	4:55089802-55089802,	PATHOGENIC	0.98378	20579941
KDR	6307	COSM6912004,	lung	carcinoma	p.W1071*	Substitution - Nonsense	4:55089782-55089782,	PATHOGENIC	0.98378	28481359
KDR	6307	COSM6005667,	prostate	carcinoma	p.A1065T	Substitution - Missense	4:55089802-55089802,	PATHOGENIC	0.98378	20579941
KDR	6307	COSM6005667,	prostate	carcinoma	p.A1065T	Substitution - Missense	4:55089802-55089802,	PATHOGENIC	0.98378	20579941
KDR	6307	COSM6005667,	skin	malignant_melanoma	p.A1065T	Substitution - Missense	4:55089802-55089802,	PATHOGENIC	0.98378	28481359
KDR	6307	COSM6964464,	skin	malignant_melanoma	p.E1097K	Substitution - Missense	4:55089706-55089706,	PATHOGENIC	0.98378	28481359
KDR	6307	COSM6912004,	skin	malignant_melanoma	p.W1071*	Substitution - Nonsense	4:55089782-55089782,	PATHOGENIC	0.98378	28481359
KDR	6307	COSM6918995,	lung	carcinoma	p.R962P	Substitution - Missense	4:55094888-55094888,	PATHOGENIC	0.9837	28481359
KDR	6307	COSM6934835,	lung	carcinoma	p.L161H	Substitution - Missense	4:55115288-55115288,	PATHOGENIC	0.98327	28481359
KDR	6307	COSM6949825,	urinary_tract	carcinoma	p.I1077V	Substitution - Missense	4:55089766-55089766,	PATHOGENIC	0.98263	28481359
KDR	6307	COSM5369850,	lung	carcinoma	p.R962L	Substitution - Missense	4:55094888-55094888,	PATHOGENIC	0.98258	26164066
KDR	6307	COSM249484,	kidney	carcinoma	p.N719S	Substitution - Missense	4:55102007-55102007,	PATHOGENIC	0.98253	22138691
KDR	6307	COSM1430203,	large_intestine	carcinoma	p.G1145R	Substitution - Missense	4:55088945-55088945,	PATHOGENIC	0.98215	28481359
KDR	6307	COSM1430203,	lung	carcinoma	p.G1145R	Substitution - Missense	4:55088945-55088945,	PATHOGENIC	0.98215	23907151
KDR	6307	COSM1430203,	NS	malignant_melanoma	p.G1145R	Substitution - Missense	4:55088945-55088945,	PATHOGENIC	0.98215	25148578
KDR	6307	COSM1430203,	breast	carcinoma	p.G1145R	Substitution - Missense	4:55088945-55088945,	PATHOGENIC	0.98215	25850943
KDR	6307	COSM5546637,	breast	carcinoma	p.L886F	Substitution - Missense	4:55096301-55096301,	PATHOGENIC	0.98146	26527317
KDR	6307	COSM6952586,	lung	carcinoma	p.T649S	Substitution - Missense	4:55104685-55104685,	PATHOGENIC	0.98128	28481359
KDR	6307	COSM6437958,	large_intestine	carcinoma	p.T1138A	Substitution - Missense	4:55088966-55088966,	PATHOGENIC	0.98107	27756406
KDR	6307	COSM6984375,	endometrium	carcinoma	p.N495H	Substitution - Missense	4:55106740-55106740,	PATHOGENIC	0.98093	28481359
KDR	6307	COSM6977687,	lung	carcinoma	p.W260*	Substitution - Nonsense	4:55114144-55114144,	PATHOGENIC	0.98047	28481359
KDR	6307	COSM6965633,	lung	carcinoma	p.C246Y	Substitution - Missense	4:55114187-55114187,	PATHOGENIC	0.98037	28481359
KDR	6307	COSM6933973,	skin	malignant_melanoma	p.T649I	Substitution - Missense	4:55104684-55104684,	PATHOGENIC	0.98027	28481359
KDR	6307	COSM6437953,	large_intestine	carcinoma	p.G1172S	Substitution - Missense	4:55087755-55087755,	PATHOGENIC	0.98016	27756406
KDR	6307	COSM6953497,	skin	carcinoma	p.?	Unknown	4:55087759-55087759,	PATHOGENIC	0.98016	28481359
KDR	6307	COSM5609233,	skin	malignant_melanoma	p.R842C	Substitution - Missense	4:55097752-55097752,	PATHOGENIC	0.97997	26343386
KDR	6307	COSM5609233,	salivary_gland	carcinoma	p.R842C	Substitution - Missense	4:55097752-55097752,	PATHOGENIC	0.97997	28481359
KDR	6307	COSM6966632,	lung	carcinoma	p.R842S	Substitution - Missense	4:55097752-55097752,	PATHOGENIC	0.97942	28481359
KDR	6307	COSM6927734,	lung	carcinoma	p.V159L	Substitution - Missense	4:55115295-55115295,	PATHOGENIC	0.97921	28481359
KDR	6307	COSM5369695,	soft_tissue	synovial_sarcoma	p.T861S	Substitution - Missense	4:55097695-55097695,	PATHOGENIC	0.97913	26415226
KDR	6307	COSM232598,	skin	carcinoma	p.G494E	Substitution - Missense	4:55106742-55106742,	PATHOGENIC	0.97864	28481359
KDR	6307	COSM6941128,	NS	carcinoma	p.V1263A	Substitution - Missense	4:55082016-55082016,	PATHOGENIC	0.97837	28481359
KDR	6307	COSM6941128,	NS	carcinoma	p.V1263A	Substitution - Missense	4:55082016-55082016,	PATHOGENIC	0.97837	28481359
KDR	6307	COSM48463,	lung	carcinoma	p.S984T	Substitution - Missense	4:55094822-55094822,	PATHOGENIC	0.97749	18948947
KDR	6307	COSM4604897,	upper_aerodigestive_tract	carcinoma	p.A853S	Substitution - Missense	4:55097719-55097719,	PATHOGENIC	0.97743	25056374
KDR	6307	COSM3780305,	large_intestine	carcinoma	p.R946H	Substitution - Missense	4:55094936-55094936,	PATHOGENIC	0.9773	28481359
KDR	6307	COSM6912865,	lung	carcinoma	p.P1243A	Substitution - Missense	4:55082571-55082571,	PATHOGENIC	0.97669	28481359
KDR	6307	COSM6939110,	lung	carcinoma	p.G493*	Substitution - Nonsense	4:55106746-55106746,	PATHOGENIC	0.97616	28481359
KDR	6307	COSM5609230,	skin	malignant_melanoma	p.P1243Q	Substitution - Missense	4:55082570-55082570,	PATHOGENIC	0.97609	26343386
KDR	6307	COSM327100,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R57T	Substitution - Missense	4:55118792-55118792,	PATHOGENIC	0.97588	22675565
KDR	6307	COSM3301546,	skin	carcinoma	p.A853V	Substitution - Missense	4:55097718-55097718,	PATHOGENIC	0.97573	28481359
KDR	6307	COSM4605220,	upper_aerodigestive_tract	carcinoma	p.V1236E	Substitution - Missense	4:55082591-55082591,	PATHOGENIC	0.97546	25056374
KDR	6307	COSM6970167,	lung	carcinoma	p.K835E	Substitution - Missense	4:55098143-55098143,	PATHOGENIC	0.97536	28481359
KDR	6307	COSM6975605,	soft_tissue	angiosarcoma	p.L88V	Substitution - Missense	4:55118700-55118700,	PATHOGENIC	0.97531	28481359
KDR	6307	COSM6946145,	large_intestine	carcinoma	p.D225Y	Substitution - Missense	4:55114251-55114251,	PATHOGENIC	0.97459	28481359
KDR	6307	COSM5609231,	skin	malignant_melanoma	p.G493E	Substitution - Missense	4:55106745-55106745,	PATHOGENIC	0.97442	26343386
KDR	6307	COSM6914735,	ovary	carcinoma	p.V159M	Substitution - Missense	4:55115295-55115295,	PATHOGENIC	0.97416	28481359
KDR	6307	COSM6954979,	large_intestine	carcinoma	p.G909E	Substitution - Missense	4:55096231-55096231,	PATHOGENIC	0.97394	28481359
KDR	6307	COSM6954979,	skin	malignant_melanoma	p.G909E	Substitution - Missense	4:55096231-55096231,	PATHOGENIC	0.97394	28481359
KDR	6307	COSM6962826,	prostate	carcinoma	p.R962C	Substitution - Missense	4:55094889-55094889,	PATHOGENIC	0.97373	28481359
KDR	6307	COSM4992133,	skin	carcinoma	p.E815K	Substitution - Missense	4:55098203-55098203,	PATHOGENIC	0.97334	25589618
KDR	6307	COSM192180,	NS	malignant_melanoma	p.T677M	Substitution - Missense	4:55102466-55102466,	PATHOGENIC	0.97327	28481359
KDR	6307	COSM192180,	prostate	carcinoma	p.T677M	Substitution - Missense	4:55102466-55102466,	PATHOGENIC	0.97327	28481359
KDR	6307	COSM6006370,	NS	malignant_melanoma	p.S1193F	Substitution - Missense	4:55087691-55087691,	PATHOGENIC	0.97307	25148578
KDR	6307	COSM6935788,	central_nervous_system	glioma	p.E764K	Substitution - Missense	4:55098780-55098780,	PATHOGENIC	0.97306	28481359
KDR	6307	COSM327103,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R962H	Substitution - Missense	4:55094888-55094888,	PATHOGENIC	0.97279	22675565
KDR	6307	COSM6955571,	urinary_tract	carcinoma	p.S1266*	Substitution - Nonsense	4:55082007-55082007,	PATHOGENIC	0.97271	28481359
KDR	6307	COSM6971683,	NS	malignant_melanoma	p.L400F	Substitution - Missense	4:55110460-55110460,	PATHOGENIC	0.97266	28481359
KDR	6307	COSM6917662,	lung	carcinoma	p.A860E	Substitution - Missense	4:55097697-55097697,	PATHOGENIC	0.97263	28481359
KDR	6307	COSM6953780,	skin	carcinoma	p.S128F	Substitution - Missense	4:55115387-55115387,	PATHOGENIC	0.97261	28481359
KDR	6307	COSM6956641,	breast	carcinoma	p.L882V	Substitution - Missense	4:55096313-55096313,	PATHOGENIC	0.97219	28481359
KDR	6307	COSM6946143,	large_intestine	carcinoma	p.D1274Y	Substitution - Missense	4:55081984-55081984,	PATHOGENIC	0.97217	28481359
KDR	6307	COSM3301581,	large_intestine	carcinoma	p.E361*	Substitution - Nonsense	4:55110664-55110664,	PATHOGENIC	0.97144	28481359
KDR	6307	COSM6978572,	central_nervous_system	glioma	p.R833Q	Substitution - Missense	4:55098148-55098148,	PATHOGENIC	0.97135	28481359
KDR	6307	COSM4484665,	skin	adnexal_tumour	p.R946C	Substitution - Missense	4:55094937-55094937,	PATHOGENIC	0.97122	28481359
KDR	6307	COSM4484665,	central_nervous_system	glioma	p.R946C	Substitution - Missense	4:55094937-55094937,	PATHOGENIC	0.97122	28481359
KDR	6307	COSM3301530,	prostate	carcinoma	p.R1066C	Substitution - Missense	4:55089799-55089799,	PATHOGENIC	0.97083	28481359
KDR	6307	COSM3301530,	prostate	carcinoma	p.R1066C	Substitution - Missense	4:55089799-55089799,	PATHOGENIC	0.97083	28481359
KDR	6307	COSM6928007,	urinary_tract	carcinoma	p.R791W	Substitution - Missense	4:55098699-55098699,	PATHOGENIC	0.97071	28481359
KDR	6307	COSM6928007,	large_intestine	carcinoma	p.R791W	Substitution - Missense	4:55098699-55098699,	PATHOGENIC	0.97071	28481359
KDR	6307	COSM6922263,	lung	carcinoma	p.Y1130F	Substitution - Missense	4:55089389-55089389,	PATHOGENIC	0.97061	28481359
KDR	6307	COSM6957339,	penis	carcinoma	p.V686F	Substitution - Missense	4:55102440-55102440,	PATHOGENIC	0.96976	28481359
KDR	6307	COSM6946840,	stomach	carcinoma	p.H653Y	Substitution - Missense	4:55104673-55104673,	PATHOGENIC	0.96948	28481359
KDR	6307	COSM4992127,	large_intestine	carcinoma	p.E1203K	Substitution - Missense	4:55087662-55087662,	PATHOGENIC	0.9693	27756406
KDR	6307	COSM4992127,	skin	carcinoma	p.E1203K	Substitution - Missense	4:55087662-55087662,	PATHOGENIC	0.9693	25589618
KDR	6307	COSM6962875,	skin	malignant_melanoma	p.L782F	Substitution - Missense	4:55098726-55098726,	PATHOGENIC	0.96923	28481359
KDR	6307	COSM48462,	lung	carcinoma	p.L1140M	Substitution - Missense	4:55088960-55088960,	PATHOGENIC	0.96916	18948947
KDR	6307	COSM1131107,	soft_tissue	haemangioblastoma	p.V297I	Substitution - Missense	4:55113391-55113391,	PATHOGENIC	0.96877	25589003
KDR	6307	COSM1131107,	soft_tissue	haemangioblastoma	p.V297I	Substitution - Missense	4:55113391-55113391,	PATHOGENIC	0.96877	25589003
KDR	6307	COSM1131107,	soft_tissue	haemangioblastoma	p.V297I	Substitution - Missense	4:55113391-55113391,	PATHOGENIC	0.96877	25589003
KDR	6307	COSM1131107,	soft_tissue	haemangioblastoma	p.V297I	Substitution - Missense	4:55113391-55113391,	PATHOGENIC	0.96877	25589003
KDR	6307	COSM1131107,	autonomic_ganglia	olfactory_neuroblastoma	p.V297I	Substitution - Missense	4:55113391-55113391,	PATHOGENIC	0.96877	27149458
KDR	6307	COSM6921379,	soft_tissue	sarcoma	p.Q645E	Substitution - Missense	4:55104697-55104697,	PATHOGENIC	0.96845	28481359
KDR	6307	COSM6921379,	soft_tissue	sarcoma	p.Q645E	Substitution - Missense	4:55104697-55104697,	PATHOGENIC	0.96845	28481359
KDR	6307	COSM6913866,	skin	malignant_melanoma	p.Q520*	Substitution - Nonsense	4:55105919-55105919,	PATHOGENIC	0.96809	28481359
KDR	6307	COSM6913866,	skin	malignant_melanoma	p.Q520*	Substitution - Nonsense	4:55105919-55105919,	PATHOGENIC	0.96809	28481359
KDR	6307	COSM4992138,	skin	carcinoma	p.E579Q	Substitution - Missense	4:55104895-55104895,	PATHOGENIC	0.96726	25589618
KDR	6307	COSM6437962,	large_intestine	carcinoma	p.D1174N	Substitution - Missense	4:55087749-55087749,	PATHOGENIC	0.96502	27756406
KDR	6307	COSM6437962,	large_intestine	carcinoma	p.D1174N	Substitution - Missense	4:55087749-55087749,	PATHOGENIC	0.96502	27756406
KDR	6307	COSM6980354,	lung	carcinoma	p.G255W	Substitution - Missense	4:55114161-55114161,	PATHOGENIC	0.96493	28481359
KDR	6307	COSM3604536,	lung	carcinoma	p.D1189N	Substitution - Missense	4:55087704-55087704,	PATHOGENIC	0.96468	26164066
KDR	6307	COSM6963463,	skin	carcinoma	p.Y1130S	Substitution - Missense	4:55089389-55089389,	PATHOGENIC	0.96442	28481359
KDR	6307	COSM48464,	lung	carcinoma	p.A973S	Substitution - Missense	4:55094856-55094856,	PATHOGENIC	0.96374	18948947
KDR	6307	COSM6980633,	large_intestine	carcinoma	p.F945C	Substitution - Missense	4:55094939-55094939,	PATHOGENIC	0.96328	28481359
KDR	6307	COSM6962682,	lung	carcinoma	p.Y448N	Substitution - Missense	4:55107807-55107807,	PATHOGENIC	0.96287	28481359
KDR	6307	COSM1319322,	skin	malignant_melanoma	p.S264F	Substitution - Missense	4:55114133-55114133,	PATHOGENIC	0.96267	28481359
KDR	6307	COSM6966649,	lung	carcinoma	p.A1265P	Substitution - Missense	4:55082011-55082011,	PATHOGENIC	0.96248	28481359
KDR	6307	COSM6437956,	large_intestine	carcinoma	p.Y224D	Substitution - Missense	4:55114254-55114254,	PATHOGENIC	0.96239	27756406
KDR	6307	COSM5609241,	skin	malignant_melanoma	p.E251K	Substitution - Missense	4:55114173-55114173,	PATHOGENIC	0.95979	26343386
KDR	6307	COSM5609241,	skin	adnexal_tumour	p.E251K	Substitution - Missense	4:55114173-55114173,	PATHOGENIC	0.95979	27311873
KDR	6307	COSM3734769,	small_intestine	carcinoma	p.S982Y	Substitution - Missense	4:55094828-55094828,	PATHOGENIC	0.95964	24797764
KDR	6307	COSM6929563,	large_intestine	carcinoma	p.Q56*	Substitution - Nonsense	4:55118796-55118796,	PATHOGENIC	0.95954	28481359
KDR	6307	COSM6437961,	large_intestine	carcinoma	p.D1174E	Substitution - Missense	4:55087747-55087747,	PATHOGENIC	0.95864	27756406
KDR	6307	COSM6437960,	large_intestine	carcinoma	p.D225N	Substitution - Missense	4:55114251-55114251,	PATHOGENIC	0.95861	27756406
KDR	6307	COSM6437960,	large_intestine	carcinoma	p.D225N	Substitution - Missense	4:55114251-55114251,	PATHOGENIC	0.95861	27756406
KDR	6307	COSM39124,	central_nervous_system	glioma	p.V1041M	Substitution - Missense	4:55090027-55090027,	PATHOGENIC	0.95817	18772396
KDR	6307	COSM6950350,	pancreas	carcinoma	p.D1174E	Substitution - Missense	4:55087747-55087747,	PATHOGENIC	0.95756	28481359
KDR	6307	COSM6946885,	kidney	carcinoma	p.Y396*	Substitution - Nonsense	4:55110470-55110470,	PATHOGENIC	0.9575	28481359
KDR	6307	COSM4605239,	upper_aerodigestive_tract	carcinoma	p.E1268D	Substitution - Missense	4:55082000-55082000,	PATHOGENIC	0.95717	25056374
KDR	6307	COSM6979272,	lung	carcinoma	p.S1299*	Substitution - Nonsense	4:55080116-55080116,	PATHOGENIC	0.95686	28481359
KDR	6307	COSM6984374,	endometrium	carcinoma	p.D710Y	Substitution - Missense	4:55102368-55102368,	PATHOGENIC	0.95602	28481359
KDR	6307	COSM6941715,	lung	carcinoma	p.H546Y	Substitution - Missense	4:55105841-55105841,	PATHOGENIC	0.95567	28481359
KDR	6307	COSM4878322,	breast	carcinoma	p.S112L	Substitution - Missense	4:55118627-55118627,	PATHOGENIC	0.95555	28481359
KDR	6307	COSM4878322,	lung	carcinoma	p.S112L	Substitution - Missense	4:55118627-55118627,	PATHOGENIC	0.95555	28481359
KDR	6307	COSM5609232,	skin	malignant_melanoma	p.I626I	Substitution - coding silent	4:55104752-55104752,	PATHOGENIC	0.95466	26343386
KDR	6307	COSM6933592,	lung	carcinoma	p.K317*	Substitution - Nonsense	4:55113331-55113331,	PATHOGENIC	0.95437	28481359
KDR	6307	COSM6941931,	NS	malignant_melanoma	p.G942R	Substitution - Missense	4:55094949-55094949,	PATHOGENIC	0.95345	28481359
KDR	6307	COSM1131108,	large_intestine	carcinoma	p.R1032*	Substitution - Nonsense	4:55090054-55090054,	PATHOGENIC	0.95123	28481359
KDR	6307	COSM1131108,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R1032*	Substitution - Nonsense	4:55090054-55090054,	PATHOGENIC	0.95123	22976956
KDR	6307	COSM6961793,	stomach	carcinoma	p.R1051W	Substitution - Missense	4:55089997-55089997,	PATHOGENIC	0.95084	28481359
KDR	6307	COSM6927305,	lung	carcinoma	p.L983F	Substitution - Missense	4:55094826-55094826,	PATHOGENIC	0.95062	28481359
KDR	6307	COSM6936241,	lung	carcinoma	p.E361G	Substitution - Missense	4:55110663-55110663,	PATHOGENIC	0.9506	28481359
KDR	6307	COSM6437959,	large_intestine	carcinoma	p.D276N	Substitution - Missense	4:55113454-55113454,	PATHOGENIC	0.95059	27756406
KDR	6307	COSM6917040,	cervix	carcinoma	p.S633Y	Substitution - Missense	4:55104732-55104732,	PATHOGENIC	0.95025	28481359
KDR	6307	COSM6437964,	large_intestine	carcinoma	p.C1208Y	Substitution - Missense	4:55087646-55087646,	PATHOGENIC	0.95011	27756406
KDR	6307	COSM75106,	skin	carcinoma	p.D180N	Substitution - Missense	4:55114994-55114994,	PATHOGENIC	0.94984	28481359
KDR	6307	COSM3604570,	skin	malignant_melanoma	p.Q67Q	Substitution - coding silent	4:55118761-55118761,	PATHOGENIC	0.94976	26343386
KDR	6307	COSM6955380,	large_intestine	carcinoma	p.D257A	Substitution - Missense	4:55114154-55114154,	PATHOGENIC	0.94949	28481359
KDR	6307	COSM6191559,	lung	carcinoma	p.S1311F	Substitution - Missense	4:55080080-55080080,	PATHOGENIC	0.94936	26645239
KDR	6307	COSM6006366,	NS	malignant_melanoma	p.H1310Y	Substitution - Missense	4:55080084-55080084,	PATHOGENIC	0.94936	25148578
KDR	6307	COSM6191559,	upper_aerodigestive_tract	carcinoma	p.S1311F	Substitution - Missense	4:55080080-55080080,	PATHOGENIC	0.94936	28481359
KDR	6307	COSM6981188,	skin	malignant_melanoma	p.S1307F	Substitution - Missense	4:55080092-55080092,	PATHOGENIC	0.94936	28481359
KDR	6307	COSM5945639,	central_nervous_system	glioma	p.N158S	Substitution - Missense	4:55115297-55115297,	PATHOGENIC	0.94914	27425854
KDR	6307	COSM5945639,	central_nervous_system	glioma	p.N158S	Substitution - Missense	4:55115297-55115297,	PATHOGENIC	0.94914	27425854
KDR	6307	COSM5414905,	breast	carcinoma	p.D60H	Substitution - Missense	4:55118784-55118784,	PATHOGENIC	0.94857	28481359
KDR	6307	COSM6912984,	lung	carcinoma	p.Q210*	Substitution - Nonsense	4:55114904-55114904,	PATHOGENIC	0.94843	28481359
KDR	6307	COSM213169,	large_intestine	carcinoma	p.R961W	Substitution - Missense	4:55094892-55094892,	PATHOGENIC	0.94741	28481359
KDR	6307	COSM213169,	large_intestine	carcinoma	p.R961W	Substitution - Missense	4:55094892-55094892,	PATHOGENIC	0.94741	27004155
KDR	6307	COSM213169,	oesophagus	carcinoma	p.R961W	Substitution - Missense	4:55094892-55094892,	PATHOGENIC	0.94741	27105424
KDR	6307	COSM3604534,	NS	malignant_melanoma	p.H1213Y	Substitution - Missense	4:55087632-55087632,	PATHOGENIC	0.94699	25148578
KDR	6307	COSM6925672,	NS	carcinoma	p.L715F	Substitution - Missense	4:55102018-55102018,	PATHOGENIC	0.94429	28481359
KDR	6307	COSM6953943,	kidney	carcinoma	p.H879Y	Substitution - Missense	4:55096322-55096322,	PATHOGENIC	0.94358	28481359
KDR	6307	COSM6934360,	lung	carcinoma	p.K535E	Substitution - Missense	4:55105874-55105874,	PATHOGENIC	0.9435	28481359
KDR	6307	COSM6006368,	skin	carcinoma	p.S1200F	Substitution - Missense	4:55087670-55087670,	PATHOGENIC	0.94056	28481359
KDR	6307	COSM6006368,	skin	carcinoma	p.S1200F	Substitution - Missense	4:55087670-55087670,	PATHOGENIC	0.94056	28481359
KDR	6307	COSM6006368,	NS	malignant_melanoma	p.S1200F	Substitution - Missense	4:55087670-55087670,	PATHOGENIC	0.94056	25148578
KDR	6307	COSM3604558,	skin	malignant_melanoma	p.S544F	Substitution - Missense	4:55105846-55105846,	PATHOGENIC	0.93965	28481359
KDR	6307	COSM4381081,	soft_tissue	angiosarcoma	p.R720W	Substitution - Missense	4:55102005-55102005,	PATHOGENIC	0.93791	25252913
KDR	6307	COSM6957340,	penis	carcinoma	p.K510T	Substitution - Missense	4:55106694-55106694,	PATHOGENIC	0.93703	28481359
KDR	6307	COSM6954639,	large_intestine	carcinoma	p.S1181*	Substitution - Nonsense	4:55087727-55087727,	PATHOGENIC	0.93657	28481359
KDR	6307	COSM6937370,	skin	malignant_melanoma	p.G1191E	Substitution - Missense	4:55087697-55087697,	PATHOGENIC	0.93642	28481359
KDR	6307	COSM6437967,	large_intestine	carcinoma	p.D1171N	Substitution - Missense	4:55087758-55087758,	PATHOGENIC	0.9362	27756406
KDR	6307	COSM98912,	stomach	carcinoma	p.G1304C	Substitution - Missense	4:55080102-55080102,	PATHOGENIC	0.93567	21097718
KDR	6307	COSM48875,	lung	carcinoma	p.G1308*	Substitution - Nonsense	4:55080090-55080090,	PATHOGENIC	0.93567	18948947
KDR	6307	COSM1581107,	skin	malignant_melanoma	p.G671E	Substitution - Missense	4:55102484-55102484,	PATHOGENIC	0.93549	26343386
KDR	6307	COSM1581107,	central_nervous_system	glioma	p.G671E	Substitution - Missense	4:55102484-55102484,	PATHOGENIC	0.93549	28481359
KDR	6307	COSM1581107,	large_intestine	carcinoma	p.G671E	Substitution - Missense	4:55102484-55102484,	PATHOGENIC	0.93549	28481359
KDR	6307	COSM6961853,	pancreas	carcinoid-endocrine_tumour	p.?	Unknown	4:55092715-55092715,	PATHOGENIC	0.93478	28481359
KDR	6307	COSM3604571,	skin	malignant_melanoma	p.D58N	Substitution - Missense	4:55118790-55118790,	PATHOGENIC	0.93379	28481359
KDR	6307	COSM6971844,	lung	carcinoma	p.P1210H	Substitution - Missense	4:55087640-55087640,	PATHOGENIC	0.93301	28481359
KDR	6307	COSM6437968,	large_intestine	carcinoma	p.A973T	Substitution - Missense	4:55094856-55094856,	PATHOGENIC	0.93238	27756406
KDR	6307	COSM6911062,	large_intestine	carcinoma	p.V514I	Substitution - Missense	4:55105937-55105937,	PATHOGENIC	0.93157	28481359
KDR	6307	COSM6949033,	urinary_tract	carcinoma	p.E1322A	Substitution - Missense	4:55080047-55080047,	PATHOGENIC	0.92931	28481359
KDR	6307	COSM6968606,	lung	carcinoma	p.P1210T	Substitution - Missense	4:55087641-55087641,	PATHOGENIC	0.92764	28481359
KDR	6307	COSM32339,	large_intestine	carcinoma	p.R275L	Substitution - Missense	4:55113456-55113456,	PATHOGENIC	0.92759	16959974
KDR	6307	COSM6977617,	lung	carcinoma	p.C862W	Substitution - Missense	4:55097690-55097690,	PATHOGENIC	0.92604	28481359
KDR	6307	COSM4992131,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R929K	Substitution - Missense	4:55095608-55095608,	PATHOGENIC	0.92545	27683039
KDR	6307	COSM4992131,	skin	carcinoma	p.R929K	Substitution - Missense	4:55095608-55095608,	PATHOGENIC	0.92545	25589618
KDR	6307	COSM6909488,	urinary_tract	carcinoma	p.E540D	Substitution - Missense	4:55105857-55105857,	PATHOGENIC	0.9251	28481359
KDR	6307	COSM3301611,	liver	carcinoma	p.A45D	Substitution - Missense	4:55121124-55121124,	PATHOGENIC	0.92404	28481359
KDR	6307	COSM1567306,	upper_aerodigestive_tract	carcinoma	p.G1308R	Substitution - Missense	4:55080090-55080090,	PATHOGENIC	0.92385	25056374
KDR	6307	COSM5743024,	urinary_tract	carcinoma	p.G1304S	Substitution - Missense	4:55080102-55080102,	PATHOGENIC	0.92385	28481359
KDR	6307	COSM1567306,	skin	adnexal_tumour	p.G1308R	Substitution - Missense	4:55080090-55080090,	PATHOGENIC	0.92385	28481359
KDR	6307	COSM6006373,	NS	malignant_melanoma	p.D1313N	Substitution - Missense	4:55080075-55080075,	PATHOGENIC	0.92384	25148578
KDR	6307	COSM6926087,	lung	carcinoma	p.C445*	Substitution - Nonsense	4:55107814-55107814,	PATHOGENIC	0.9237	28481359
KDR	6307	COSM6940551,	breast	carcinoma	p.Q67H	Substitution - Missense	4:55118761-55118761,	PATHOGENIC	0.92277	28481359
KDR	6307	COSM6940551,	urinary_tract	carcinoma	p.Q67H	Substitution - Missense	4:55118761-55118761,	PATHOGENIC	0.92277	28481359
KDR	6307	COSM6307655,	liver	carcinoma	p.Q1225K	Substitution - Missense	4:55082625-55082625,	PATHOGENIC	0.92197	28481359
KDR	6307	COSM6191363,	lung	carcinoma	p.V986I	Substitution - Missense	4:55094817-55094817,	PATHOGENIC	0.92176	27056568
KDR	6307	COSM1430216,	skin	malignant_melanoma	p.E732K	Substitution - Missense	4:55101969-55101969,	PATHOGENIC	0.92138	28481359
KDR	6307	COSM1430216,	skin	malignant_melanoma	p.E732K	Substitution - Missense	4:55101969-55101969,	PATHOGENIC	0.92138	28481359
KDR	6307	COSM1430216,	skin	carcinoma	p.E732K	Substitution - Missense	4:55101969-55101969,	PATHOGENIC	0.92138	28481359
KDR	6307	COSM3734768,	small_intestine	carcinoma	p.S1303G	Substitution - Missense	4:55080105-55080105,	PATHOGENIC	0.9191	24797764
KDR	6307	COSM6437955,	large_intestine	carcinoma	p.E1325K	Substitution - Missense	4:55080039-55080039,	PATHOGENIC	0.91697	27756406
KDR	6307	COSM6437955,	lung	carcinoma	p.E1325K	Substitution - Missense	4:55080039-55080039,	PATHOGENIC	0.91697	28481359
KDR	6307	COSM1694406,	lung	carcinoma	p.S1281F	Substitution - Missense	4:55081962-55081962,	PATHOGENIC	0.91565	28481359
KDR	6307	COSM6958270,	urinary_tract	carcinoma	p.L1164F	Substitution - Missense	4:55088886-55088886,	PATHOGENIC	0.91528	28481359
KDR	6307	COSM6919155,	liver	carcinoma	p.T186N	Substitution - Missense	4:55114975-55114975,	PATHOGENIC	0.91479	28481359
KDR	6307	COSM6956007,	lung	carcinoma	p.Y584F	Substitution - Missense	4:55104879-55104879,	PATHOGENIC	0.91437	28481359
KDR	6307	COSM3301525,	NS	carcinoma	p.R1126S	Substitution - Missense	4:55089400-55089400,	PATHOGENIC	0.91413	28481359
KDR	6307	COSM6986027,	breast	carcinoma	p.A954V	Substitution - Missense	4:55094912-55094912,	PATHOGENIC	0.91172	28481359
KDR	6307	COSM6974205,	prostate	carcinoma	p.V219L	Substitution - Missense	4:55114877-55114877,	PATHOGENIC	0.90956	28481359
KDR	6307	COSM6954233,	breast	carcinoma	p.D1254H	Substitution - Missense	4:55082538-55082538,	PATHOGENIC	0.9095	28481359
KDR	6307	COSM6966114,	skin	malignant_melanoma	p.Q947*	Substitution - Nonsense	4:55094934-55094934,	PATHOGENIC	0.90625	28481359
KDR	6307	COSM5609235,	skin	malignant_melanoma	p.L606L	Substitution - coding silent	4:55104812-55104812,	PATHOGENIC	0.90345	26343386
KDR	6307	COSM6926782,	skin	carcinoma	p.S123A	Substitution - Missense	4:55115403-55115403,	PATHOGENIC	0.89914	28481359
KDR	6307	COSM6962681,	lung	carcinoma	p.R946S	Substitution - Missense	4:55094937-55094937,	PATHOGENIC	0.89898	28481359
KDR	6307	COSM3604563,	skin	carcinoma	p.E464K	Substitution - Missense	4:55107759-55107759,	PATHOGENIC	0.89666	25589618
KDR	6307	COSM6904748,	thyroid	carcinoma	p.R961Q	Substitution - Missense	4:55094891-55094891,	PATHOGENIC	0.89319	28351340
KDR	6307	COSM6935258,	endometrium	carcinoma	p.K241N	Substitution - Missense	4:55114201-55114201,	PATHOGENIC	0.89245	28481359
KDR	6307	COSM4992129,	skin	carcinoma	p.S982S	Substitution - coding silent	4:55094827-55094827,	PATHOGENIC	0.89063	25589618
KDR	6307	COSM249552,	kidney	carcinoma	p.V567M	Substitution - Missense	4:55104931-55104931,	PATHOGENIC	0.88804	22138691
KDR	6307	COSM6983556,	liver	carcinoma	p.D39H	Substitution - Missense	4:55121143-55121143,	PATHOGENIC	0.88195	28481359
KDR	6307	COSM1056130,	biliary_tract	carcinoma	p.S1221N	Substitution - Missense	4:55087607-55087607,	PATHOGENIC	0.88144	28481359
KDR	6307	COSM6952157,	large_intestine	carcinoma	p.K1110N	Substitution - Missense	4:55089448-55089448,	PATHOGENIC	0.88026	28481359
KDR	6307	COSM6965519,	lung	carcinoma	p.R549K	Substitution - Missense	4:55104984-55104984,	PATHOGENIC	0.87847	28481359
KDR	6307	COSM4342359,	skin	adnexal_tumour	p.G255E	Substitution - Missense	4:55114160-55114160,	PATHOGENIC	0.87723	27311873
KDR	6307	COSM6986028,	breast	carcinoma	p.N318I	Substitution - Missense	4:55113327-55113327,	PATHOGENIC	0.87678	28481359
KDR	6307	COSM94565,	large_intestine	carcinoma	p.N793S	Substitution - Missense	4:55098268-55098268,	PATHOGENIC	0.87578	27023146
KDR	6307	COSM94565,	large_intestine	carcinoma	p.N793S	Substitution - Missense	4:55098268-55098268,	PATHOGENIC	0.87578	27023146
KDR	6307	COSM94565,	large_intestine	carcinoma	p.N793S	Substitution - Missense	4:55098268-55098268,	PATHOGENIC	0.87578	27023146
KDR	6307	COSM94565,	large_intestine	carcinoma	p.N793S	Substitution - Missense	4:55098268-55098268,	PATHOGENIC	0.87578	27023146
KDR	6307	COSM94565,	large_intestine	carcinoma	p.N793S	Substitution - Missense	4:55098268-55098268,	PATHOGENIC	0.87578	27023146
KDR	6307	COSM94565,	lung	carcinoma	p.N793S	Substitution - Missense	4:55098268-55098268,	PATHOGENIC	0.87578	20668451
KDR	6307	COSM3301560,	skin	malignant_melanoma	p.Q697Q	Substitution - coding silent	4:55102405-55102405,	PATHOGENIC	0.87535	26343386
KDR	6307	COSM1430205,	large_intestine	carcinoma	p.R1118*	Substitution - Nonsense	4:55089426-55089426,	PATHOGENIC	0.87341	28481359
KDR	6307	COSM1430205,	soft_tissue	sarcoma	p.R1118*	Substitution - Nonsense	4:55089426-55089426,	PATHOGENIC	0.87341	28481359
KDR	6307	COSM6937277,	NS	malignant_melanoma	p.E1323K	Substitution - Missense	4:55080045-55080045,	PATHOGENIC	0.87131	28481359
KDR	6307	COSM6444786,	endometrium	carcinoma	p.K168N	Substitution - Missense	4:55115028-55115028,	PATHOGENIC	0.87045	27159395
KDR	6307	COSM6444786,	endometrium	carcinoma	p.K168N	Substitution - Missense	4:55115028-55115028,	PATHOGENIC	0.87045	27159395
KDR	6307	COSM6951458,	oesophagus	carcinoma	p.Q492*	Substitution - Nonsense	4:55106749-55106749,	PATHOGENIC	0.86661	28481359
KDR	6307	COSM3301558,	upper_aerodigestive_tract	carcinoma	p.L707I	Substitution - Missense	4:55102377-55102377,	PATHOGENIC	0.86462	28481359
KDR	6307	COSM6006372,	NS	malignant_melanoma	p.E1206K	Substitution - Missense	4:55087653-55087653,	PATHOGENIC	0.86462	25148578
KDR	6307	COSM6006372,	large_intestine	carcinoma	p.E1206K	Substitution - Missense	4:55087653-55087653,	PATHOGENIC	0.86462	27756406
KDR	6307	COSM6006372,	large_intestine	carcinoma	p.E1206K	Substitution - Missense	4:55087653-55087653,	PATHOGENIC	0.86462	27756406
KDR	6307	COSM48461,	lung	carcinoma	p.G1145E	Substitution - Missense	4:55088944-55088944,	PATHOGENIC	0.8605	18948947
KDR	6307	COSM48461,	NS	malignant_melanoma	p.G1145E	Substitution - Missense	4:55088944-55088944,	PATHOGENIC	0.8605	25148578
KDR	6307	COSM6946144,	large_intestine	carcinoma	p.E1038D	Substitution - Missense	4:55090034-55090034,	PATHOGENIC	0.85814	28481359
KDR	6307	COSM4992130,	skin	carcinoma	p.R929R	Substitution - coding silent	4:55095607-55095607,	PATHOGENIC	0.85611	25589618
KDR	6307	COSM6437954,	large_intestine	carcinoma	p.E235K	Substitution - Missense	4:55114221-55114221,	PATHOGENIC	0.85495	27756406
KDR	6307	COSM6959786,	lung	carcinoma	p.E1206V	Substitution - Missense	4:55087652-55087652,	PATHOGENIC	0.85205	28481359
KDR	6307	COSM3301554,	endometrium	carcinoma	p.R725H	Substitution - Missense	4:55101989-55101989,	PATHOGENIC	0.84993	28481359
KDR	6307	COSM6911466,	NS	malignant_melanoma	p.K1110*	Substitution - Nonsense	4:55089450-55089450,	PATHOGENIC	0.8479	28481359
KDR	6307	COSM6918609,	skin	carcinoma	p.T298A	Substitution - Missense	4:55113388-55113388,	PATHOGENIC	0.84356	28481359
KDR	6307	COSM3604533,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R1229Q	Substitution - Missense	4:55082612-55082612,	PATHOGENIC	0.84209	28481359
KDR	6307	COSM5609237,	skin	malignant_melanoma	p.L811L	Substitution - coding silent	4:55098213-55098213,	PATHOGENIC	0.83714	26343386
KDR	6307	COSM6444785,	endometrium	carcinoma	p.I94S	Substitution - Missense	4:55118681-55118681,	PATHOGENIC	0.83566	27159395
KDR	6307	COSM6986291,	soft_tissue	gastrointestinal_stromal_tumour	p.K981R	Substitution - Missense	4:55094831-55094831,	PATHOGENIC	0.83414	28481359
KDR	6307	COSM1056139,	skin	carcinoma	p.R944Q	Substitution - Missense	4:55094942-55094942,	PATHOGENIC	0.83254	25589618
KDR	6307	COSM1056139,	skin	malignant_melanoma	p.R944Q	Substitution - Missense	4:55094942-55094942,	PATHOGENIC	0.83254	28481359
KDR	6307	COSM1056139,	skin	malignant_melanoma	p.R944Q	Substitution - Missense	4:55094942-55094942,	PATHOGENIC	0.83254	26343386
KDR	6307	COSM4992134,	skin	carcinoma	p.I785I	Substitution - coding silent	4:55098715-55098715,	PATHOGENIC	0.83061	25589618
KDR	6307	COSM6915523,	endometrium	carcinoma	p.R249I	Substitution - Missense	4:55114178-55114178,	PATHOGENIC	0.82505	28481359
KDR	6307	COSM6915523,	large_intestine	carcinoma	p.R249I	Substitution - Missense	4:55114178-55114178,	PATHOGENIC	0.82505	28481359
KDR	6307	COSM6925141,	autonomic_ganglia	paraganglioma	p.N1226K	Substitution - Missense	4:55082620-55082620,	PATHOGENIC	0.82403	28481359
KDR	6307	COSM5609236,	skin	malignant_melanoma	p.G692G	Substitution - coding silent	4:55102420-55102420,	PATHOGENIC	0.82389	26343386
KDR	6307	COSM1056145,	large_intestine	carcinoma	p.E685K	Substitution - Missense	4:55102443-55102443,	PATHOGENIC	0.82191	28481359
KDR	6307	COSM1056145,	large_intestine	carcinoma	p.E685K	Substitution - Missense	4:55102443-55102443,	PATHOGENIC	0.82191	28481359
KDR	6307	COSM6917076,	NS	carcinoma	p.D30Y	Substitution - Missense	4:55121170-55121170,	PATHOGENIC	0.81922	28481359
KDR	6307	COSM4992132,	skin	malignant_melanoma	p.F829F	Substitution - coding silent	4:55098159-55098159,	PATHOGENIC	0.81116	26343386
KDR	6307	COSM4992132,	skin	carcinoma	p.F829F	Substitution - coding silent	4:55098159-55098159,	PATHOGENIC	0.81116	25589618
KDR	6307	COSM6923576,	urinary_tract	carcinoma	p.N141K	Substitution - Missense	4:55115347-55115347,	PATHOGENIC	0.80951	28481359
KDR	6307	COSM6006371,	NS	malignant_melanoma	p.M1202I	Substitution - Missense	4:55087663-55087663,	PATHOGENIC	0.79895	25148578
KDR	6307	COSM48460,	lung	carcinoma	p.P1210L	Substitution - Missense	4:55087640-55087640,	PATHOGENIC	0.79798	18948947
KDR	6307	COSM6938959,	large_intestine	carcinoma	p.E1182D	Substitution - Missense	4:55087723-55087723,	PATHOGENIC	0.79466	28481359
KDR	6307	COSM4695078,	bone	osteosarcoma	p.A521V	Substitution - Missense	4:55105915-55105915,	PATHOGENIC	0.79166	27499911
KDR	6307	COSM6979304,	lung	carcinoma	p.S618C	Substitution - Missense	4:55104777-55104777,	PATHOGENIC	0.78402	28481359
KDR	6307	COSM6969986,	lung	carcinoma	p.G1284R	Substitution - Missense	4:55080162-55080162,	PATHOGENIC	0.78384	28481359
KDR	6307	COSM5991538,	NS	malignant_melanoma	p.R249K	Substitution - Missense	4:55114178-55114178,	PATHOGENIC	0.78326	25148578
KDR	6307	COSM5991538,	skin	adnexal_tumour	p.R249K	Substitution - Missense	4:55114178-55114178,	PATHOGENIC	0.78326	27311873
KDR	6307	COSM6437965,	large_intestine	carcinoma	p.C1201Y	Substitution - Missense	4:55087667-55087667,	PATHOGENIC	0.77389	27756406
KDR	6307	COSM6970021,	breast	carcinoma	p.D30H	Substitution - Missense	4:55121170-55121170,	PATHOGENIC	0.7699	28481359
KDR	6307	COSM1310139,	NS	malignant_melanoma	p.S1279F	Substitution - Missense	4:55081968-55081968,	PATHOGENIC	0.75352	28481359
KDR	6307	COSM6437963,	large_intestine	carcinoma	p.V1199I	Substitution - Missense	4:55087674-55087674,	PATHOGENIC	0.7524	27756406
KDR	6307	COSM6437963,	large_intestine	carcinoma	p.V1199I	Substitution - Missense	4:55087674-55087674,	PATHOGENIC	0.7524	27756406
KDR	6307	COSM6931542,	large_intestine	carcinoma	p.R299Q	Substitution - Missense	4:55113384-55113384,	PATHOGENIC	0.74909	28481359
KDR	6307	COSM4135812,	lung	carcinoma	p.K1230N	Substitution - Missense	4:55082608-55082608,	PATHOGENIC	0.74829	28481359
KDR	6307	COSM7325471,	biliary_tract	carcinoma	p.Q472K	Substitution - Missense	4:55106809-55106809,	PATHOGENIC	0.71599	29360550
KDR	6307	COSM6969715,	NS	carcinoma	p.D1129E	Substitution - Missense	4:55089391-55089391,	NEUTRAL	0.49899	28481359
KDR	6307	COSM6972913,	skin	carcinoma	p.T1276A	Substitution - Missense	4:55081978-55081978,	NEUTRAL	0.4921	28481359
KDR	6307	COSM6910527,	soft_tissue	leiomyosarcoma	p.N523K	Substitution - Missense	4:55105908-55105908,	NEUTRAL	0.48941	28481359
KDR	6307	COSM6962622,	upper_aerodigestive_tract	carcinoma	p.K270N	Substitution - Missense	4:55113470-55113470,	NEUTRAL	0.46629	28481359
KDR	6307	COSM3301616,	large_intestine	carcinoma	p.A10T	Substitution - Missense	4:55125266-55125266,	NEUTRAL	0.45526	28481359
KDR	6307	COSM6969445,	lung	carcinoma	p.M386T	Substitution - Missense	4:55110501-55110501,	NEUTRAL	0.44996	28481359
KDR	6307	COSM1430218,	thyroid	carcinoma	p.A690T	Substitution - Missense	4:55102428-55102428,	NEUTRAL	0.44404	28481359
KDR	6307	COSM5609239,	salivary_gland	carcinoma	p.S178F	Substitution - Missense	4:55114999-55114999,	NEUTRAL	0.42423	28481359
KDR	6307	COSM5609239,	skin	malignant_melanoma	p.S178F	Substitution - Missense	4:55114999-55114999,	NEUTRAL	0.42423	26343386
KDR	6307	COSM6977430,	genital_tract	germ_cell_tumour	p.Y305*	Substitution - Nonsense	4:55113365-55113365,	NEUTRAL	0.40899	28481359
KDR	6307	COSM6437966,	large_intestine	carcinoma	p.G948R	Substitution - Missense	4:55094931-55094931,	NEUTRAL	0.37975	27756406
KDR	6307	COSM6921322,	biliary_tract	carcinoma	p.I1330L	Substitution - Missense	4:55080024-55080024,	NEUTRAL	0.36009	28481359
KDR	6307	COSM6995470,	ovary	germ_cell_tumour	p.S687L	Substitution - Missense	4:55102436-55102436,	NEUTRAL	0.34577	28954785
KDR	6307	COSM1056144,	skin	malignant_melanoma	p.G718G	Substitution - coding silent	4:55102009-55102009,	NEUTRAL	0.3418	26343386
KDR	6307	COSM6949481,	large_intestine	carcinoma	p.N704K	Substitution - Missense	4:55102384-55102384,	NEUTRAL	0.33186	28481359
KDR	6307	COSM6950731,	skin	malignant_melanoma	p.H594Y	Substitution - Missense	4:55104850-55104850,	NEUTRAL	0.32957	28481359
KDR	6307	COSM6950731,	NS	carcinoma	p.H594Y	Substitution - Missense	4:55104850-55104850,	NEUTRAL	0.32957	28481359
KDR	6307	COSM1579010,	ovary	carcinoma	p.?	Unknown	4:55082527-55082527,	NEUTRAL	0.32674	18186519
KDR	6307	COSM4604341,	upper_aerodigestive_tract	carcinoma	p.V476V	Substitution - coding silent	4:55106795-55106795,	NEUTRAL	0.31715	25056374
KDR	6307	COSM734138,	NS	malignant_melanoma	p.R275*	Substitution - Nonsense	4:55113457-55113457,	NEUTRAL	0.30021	25148578
KDR	6307	COSM734138,	large_intestine	carcinoma	p.R275*	Substitution - Nonsense	4:55113457-55113457,	NEUTRAL	0.30021	28481359
KDR	6307	COSM7325493,	biliary_tract	carcinoma	p.T279N	Substitution - Missense	4:55113444-55113444,	NEUTRAL	0.29628	29360550
KDR	6307	COSM734137,	upper_aerodigestive_tract	carcinoma	p.L151L	Substitution - coding silent	4:55115317-55115317,	NEUTRAL	0.28267	25056374
KDR	6307	COSM6006374,	NS	malignant_melanoma	p.S1353F	Substitution - Missense	4:55079954-55079954,	NEUTRAL	0.27875	25148578
KDR	6307	COSM6912866,	lung	carcinoma	p.Q280R	Substitution - Missense	4:55113441-55113441,	NEUTRAL	0.27226	28481359
KDR	6307	COSM48465,	lung	carcinoma	p.V476L	Substitution - Missense	4:55106797-55106797,	NEUTRAL	0.23947	18948947
KDR	6307	COSM6913865,	skin	malignant_melanoma	p.T600I	Substitution - Missense	4:55104831-55104831,	NEUTRAL	0.21716	28481359
KDR	6307	COSM6951058,	skin	adnexal_tumour	p.G1348R	Substitution - Missense	4:55079970-55079970,	NEUTRAL	0.21611	28481359
KDR	6307	COSM6951058,	salivary_gland	carcinoma	p.G1348R	Substitution - Missense	4:55079970-55079970,	NEUTRAL	0.21611	28481359
KDR	6307	COSM6006369,	NS	malignant_melanoma	p.G1348E	Substitution - Missense	4:55079969-55079969,	NEUTRAL	0.19882	25148578
KDR	6307	COSM94567,	lung	carcinoma	p.H594R	Substitution - Missense	4:55104849-55104849,	NEUTRAL	0.16775	20668451
KDR	6307	COSM5533185,	skin	malignant_melanoma	p.G948G	Substitution - coding silent	4:55094929-55094929,	NEUTRAL	0.16554	26343386
KDR	6307	COSM4936555,	pancreas	carcinoma	p.R347C	Substitution - Missense	4:55110706-55110706,	NEUTRAL	0.16307	28481359
KDR	6307	COSM4936555,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R347C	Substitution - Missense	4:55110706-55110706,	NEUTRAL	0.16307	29386642
KDR	6307	COSM6968625,	lung	carcinoma	p.Q280K	Substitution - Missense	4:55113442-55113442,	NEUTRAL	0.15464	28481359
KDR	6307	COSM6971442,	stomach	carcinoma	p.T689M	Substitution - Missense	4:55102430-55102430,	NEUTRAL	0.15084	28481359
KDR	6307	COSM95976,	lung	carcinoma	p.N619N	Substitution - coding silent	4:55104773-55104773,	NEUTRAL	0.13728	20668451
KDR	6307	COSM6954868,	lung	carcinoma	p.P695T	Substitution - Missense	4:55102413-55102413,	NEUTRAL	0.12663	28481359
KDR	6307	COSM1579053,	skin	carcinoma	p.L612L	Substitution - coding silent	4:55104796-55104796,	NEUTRAL	0.12401	18186519
KDR	6307	COSM6957212,	kidney	carcinoma	p.E75*	Substitution - Nonsense	4:55118739-55118739,	NEUTRAL	0.11508	28481359
KDR	6307	COSM6966730,	NS	carcinoid-endocrine_tumour	p.R347S	Substitution - Missense	4:55110706-55110706,	NEUTRAL	0.10569	28481359
KDR	6307	COSM5369845,	lung	carcinoma	p.S231Y	Substitution - Missense	4:55114232-55114232,	NEUTRAL	0.09087	26164066
KDR	6307	COSM6904297,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.H454Q	Substitution - Missense	4:55107787-55107787,	NEUTRAL	0.08921	27248180
KDR	6307	COSM3301507,	skin	adnexal_tumour	p.T1339I	Substitution - Missense	4:55079996-55079996,	NEUTRAL	0.08749	27311873
KDR	6307	COSM98987,	stomach	carcinoma	p.G333V	Substitution - Missense	4:55110747-55110747,	NEUTRAL	0.07634	21097718
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	soft_tissue	haemangioblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	25589003
KDR	6307	COSM149673,	autonomic_ganglia	olfactory_neuroblastoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	27149458
KDR	6307	COSM149673,	skin	carcinoma	p.Q472H	Substitution - Missense	4:55106807-55106807,	NEUTRAL	0.06811	28984303
KDR	6307	COSM6951216,	lung	carcinoma	p.G1333A	Substitution - Missense	4:55080014-55080014,	NEUTRAL	0.06634	28481359
KDR	6307	COSM6940705,	central_nervous_system	glioma	p.T343K	Substitution - Missense	4:55110717-55110717,	NEUTRAL	0.06091	28481359
KDR	6307	COSM6963564,	soft_tissue	gastrointestinal_stromal_tumour	p.V1334E	Substitution - Missense	4:55080011-55080011,	NEUTRAL	0.05878	28481359
KDR	6307	COSM6006375,	NS	malignant_melanoma	p.T1349I	Substitution - Missense	4:55079966-55079966,	NEUTRAL	0.05792	25148578
KDR	6307	COSM6056920,	large_intestine	carcinoma	p.V474L	Substitution - Missense	4:55106803-55106803,	NEUTRAL	0.05717	27023146
KDR	6307	COSM6056920,	large_intestine	carcinoma	p.V474L	Substitution - Missense	4:55106803-55106803,	NEUTRAL	0.05717	27023146
KDR	6307	COSM6056920,	large_intestine	carcinoma	p.V474L	Substitution - Missense	4:55106803-55106803,	NEUTRAL	0.05717	27023146
KDR	6307	COSM6056920,	large_intestine	carcinoma	p.V474L	Substitution - Missense	4:55106803-55106803,	NEUTRAL	0.05717	27023146
KDR	6307	COSM6056920,	large_intestine	carcinoma	p.V474L	Substitution - Missense	4:55106803-55106803,	NEUTRAL	0.05717	27023146
KDR	6307	COSM5609238,	skin	malignant_melanoma	p.G537G	Substitution - coding silent	4:55105866-55105866,	NEUTRAL	0.0501	26343386
KDR	6307	COSM327101,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1331E	Substitution - coding silent	4:55080019-55080019,	NEUTRAL	0.04772	22675565
KDR	6307	COSM6959686,	large_intestine	carcinoma	p.M559I	Substitution - Missense	4:55104953-55104953,	NEUTRAL	0.04461	28481359
KDR	6307	COSM6921830,	lung	carcinoma	p.R347P	Substitution - Missense	4:55110705-55110705,	NEUTRAL	0.04416	28481359
KDR	6307	COSM6922799,	NS	malignant_melanoma	p.P481S	Substitution - Missense	4:55106782-55106782,	NEUTRAL	0.03548	28481359
KDR	6307	COSM6922799,	NS	malignant_melanoma	p.P481S	Substitution - Missense	4:55106782-55106782,	NEUTRAL	0.03548	28481359
KDR	6307	COSM6973101,	central_nervous_system	glioma	p.V533I	Substitution - Missense	4:55105880-55105880,	NEUTRAL	0.03495	28481359
KDR	6307	COSM6916340,	lung	carcinoma	p.R33M	Substitution - Missense	4:55121160-55121160,	NEUTRAL	0.03354	28481359
KDR	6307	COSM327104,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.I234M	Substitution - Missense	4:55114222-55114222,	NEUTRAL	0.03216	22675565
KDR	6307	COSM327102,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R347H	Substitution - Missense	4:55110705-55110705,	NEUTRAL	0.03137	22675565
KDR	6307	COSM327102,	large_intestine	carcinoma	p.R347H	Substitution - Missense	4:55110705-55110705,	NEUTRAL	0.03137	28481359
KDR	6307	COSM327102,	large_intestine	other	p.R347H	Substitution - Missense	4:55110705-55110705,	NEUTRAL	0.03137	28524162
KDR	6307	COSM6987661,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S21T	Substitution - Missense	4:55125233-55125233,	NEUTRAL	0.02793	28481359
KDR	6307	COSM1056153,	large_intestine	carcinoma	p.G233E	Substitution - Missense	4:55114226-55114226,	NEUTRAL	0.0253	27756406
KDR	6307	COSM5609240,	skin	malignant_melanoma	p.E346E	Substitution - coding silent	4:55110707-55110707,	NEUTRAL	0.02286	26343386
KDR	6307	COSM1579011,	ovary	carcinoma	p.A1030A	Substitution - coding silent	4:55090058-55090058,	NEUTRAL	0.0197	18186519
KDR	6307	COSM6100271,	upper_aerodigestive_tract	carcinoma	p.T668M	Substitution - Missense	4:55102493-55102493,	NEUTRAL	0.0172	28581676
KDR	6307	COSM6966202,	urinary_tract	carcinoma	p.S566N	Substitution - Missense	4:55104933-55104933,	NEUTRAL	0.01678	28481359
KDR	6307	COSM1618919,	liver	carcinoma	p.?	Unknown	4:55114120-55114120,	NEUTRAL	0.00656	Info_not_available
KDR	6307	COSM6023902,	skin	carcinoma	p.S265L	Substitution - Missense	4:55114130-55114130,	NEUTRAL	0.00593	28481359
KDR	6307	COSM6023902,	large_intestine	carcinoma	p.S265L	Substitution - Missense	4:55114130-55114130,	NEUTRAL	0.00593	27121310
KDR	6307	COSM1578963,	large_intestine	carcinoma	p.E469K	Substitution - Missense	4:55107744-55107744,	NEUTRAL	0.00346	18186519
KDR	6307	COSM1578963,	skin	malignant_melanoma	p.E469K	Substitution - Missense	4:55107744-55107744,	NEUTRAL	0.00346	28481359
KDR	6307	COSM1578963,	skin	malignant_melanoma	p.E469K	Substitution - Missense	4:55107744-55107744,	NEUTRAL	0.00346	26343386
KDR	6307	COSM1578963,	urinary_tract	carcinoma	p.E469K	Substitution - Missense	4:55107744-55107744,	NEUTRAL	0.00346	28481359
KDR	6307	COSM4605154,	upper_aerodigestive_tract	carcinoma	p.S112S	Substitution - coding silent	4:55118626-55118626,	NEUTRAL	0.00259	25056374
KDR	6307	COSM48977,	lung	carcinoma	p.P1355del	Deletion - In frame	4:55079947-55079949,	Info_not_available	Info_not_available	18948947
KDR	6307	COSM41672, COSM41673, COSM41674,	soft_tissue	angiosarcoma	p.A1065T, p.D717V, p.T771R	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19723655
KDR	6307	COSM5991627,	large_intestine	carcinoma	p.R1032*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	22014273
KDR	6307	COSM41674,	breast	carcinoma	p.A1065T	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	24569783
KDR	6307	COSM4172537, COSM4172538,	skin	malignant_melanoma	p.G282E, p.S373F	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	24628946
KDR	6307	COSM5346904,	pancreas	carcinoma	p.Q472H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25127237
KDR	6307	COSM5945731,	central_nervous_system	glioma	p.T677M	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25257301
KDR	6307	COSM5346904,	pancreas	carcinoid-endocrine_tumour	p.Q472H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25342539
KDR	6307	COSM5885094,	soft_tissue	gastrointestinal_stromal_tumour	p.N205S	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25427437
KDR	6307	COSM41674,	breast	carcinoma	p.A1065T	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25679062
KDR	6307	COSM6849488,	central_nervous_system	glioma	p.G1337S	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26191234
KDR	6307	COSM5346904,	bone	chordoma	p.Q472H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26366211
KDR	6307	COSM6191558,	lung	carcinoid-endocrine_tumour, carcinoma	p.Q472_A473>HT	Complex - compound substitution	4:55106806-55106807,	Info_not_available	Info_not_available	26645239
KDR	6307	COSM5985650,	salivary_gland	carcinoma	p.R842C	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27103403
KDR	6307	COSM5885129,	biliary_tract	carcinoma	p.R787Q	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27267833
KDR	6307	COSM5945843,	pleura	mesothelioma	p.N793S	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27507853
KDR	6307	COSM6022966,	lung	carcinoma	p.N402K	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27528220
KDR	6307	COSM5346904,	soft_tissue	fibrosarcoma	p.Q472H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28304377
KDR	6307	COSM6904485,	upper_aerodigestive_tract	carcinoma	p.Q50E	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28493366
KDR	6307	COSM3734767,	small_intestine	carcinoma	p.V1318M	Substitution - Missense	4:55080060-55080060,	Info_not_available	0.66551	24797764
KDR	6307	COSM94563,	lung	carcinoma	p.Q1344H	Substitution - Missense	4:55079980-55079980,	Info_not_available	0.65216	20668451
KDR	6307	COSM327105,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G255G	Substitution - coding silent	4:55114159-55114159,	Info_not_available	0.6306	22675565
KDR	6307	COSM1579012,	ovary	carcinoma	p.E372D	Substitution - Missense	4:55110542-55110542,	Info_not_available	0.62637	18186519
KDR	6307	COSM7325541,	biliary_tract	carcinoma	p.I1330I	Substitution - coding silent	4:55080022-55080022,	Info_not_available	0.57519	29360550
KDR	6307	COSM3604545, COSM5611321, COSM5611322,	skin	malignant_melanoma	p.D1259N, p.P956S, p.V789N	Substitution - Missense	4:55082029-55082030, 4:55094907-55094907, 4:55098704-55098705,	Info_not_available	0.53805, Info_not_available	26343386
KDR	6307	COSM6437957, COSM6437969, COSM6437970,	large_intestine	carcinoma	p.?, p.C1208fs*27	Deletion - Frameshift, Unknown	4:55087645-55087645, 4:55087762-55087762, 4:55087765-55087765,	Info_not_available	0.53167, .57509, Info_not_available	27756406
KDR	6307	COSM5991537, COSM5991539,	skin	adnexal_tumour	p.G1333fs*6, p.G255G	Insertion - Frameshift, Substitution - coding silent	4:55080016-55080017, 4:55114159-55114159,	Info_not_available	0.52623, Info_not_available	27311873
KDR	6307	COSM1056146, COSM3301603, COSM3604545, COSM6301872, COSM6909261, COSM6909807, COSM6912180, COSM6915365, COSM6917951, COSM6918972, COSM6920635, COSM6924669, COSM6929280, COSM6929366, COSM6932527, COSM6933571, COSM6934709, COSM6936842, COSM6937195, COSM6937366, COSM6938185, COSM6951287, COSM6952158, COSM6960552, COSM6961288, COSM6962435, COSM6968296, COSM6969789, COSM6969852, COSM6971050, COSM6972654, COSM6972751, COSM6974185, COSM6975071, COSM6982669, COSM6983405,	NS, breast, central_nervous_system, endometrium, kidney, large_intestine, lung, oesophagus, prostate, skin, small_intestine, soft_tissue, urinary_tract	angiosarcoma, carcinoma, glioma, leiomyosarcoma, malignant_melanoma	p.?, p.E1097fs*5, p.F1078fs*24, p.G303K, p.G493K, p.G681_E682insKG, p.G942R, p.H1144Q, p.H454fs*23, p.I212T, p.L1194fs*15, p.L29V, p.M1I, p.N143fs*5, p.N468fs*16, p.P1128fs*57, p.P1233F, p.P1355F, p.P351F, p.P588L, p.P956S, p.Q268*, p.Q422fs*7, p.R106W, p.R299L, p.R73fs*5, p.R863K, p.S1279Y, p.S178Y, p.S687fs*22, p.T678P, p.V1251fs*1, p.V595fs*7, p.V655M, p.W827_R831>*	Complex - deletion inframe, Deletion - Frameshift, Insertion - Frameshift, Insertion - In frame, Substitution - Missense, Substitution - Nonsense, Unknown	4:55079948-55079949, 4:55080152-55080167, 4:55081968-55081968, 4:55082547-55082547, 4:55082600-55082601, 4:55087688-55087689, 4:55088946-55088946, 4:55089395-55089395, 4:55089706-55089706, 4:55089761-55089761, 4:55094907-55094907, 4:55094949-55094949, 4:55097688-55097688, 4:55098154-55098165, 4:55102306-55102443, 4:55102437-55102437, 4:55102452-55102453, 4:55102464-55102464, 4:55104667-55104667, 4:55104813-55104846, 4:55104867-55104867, 4:55106745-55106746, 4:55107745-55107746, 4:55107790-55107790, 4:55107885-55107885, 4:55110693-55110694, 4:55113372-55113373, 4:55113384-55113384, 4:55113478-55113478, 4:55114897-55114897, 4:55114999-55114999, 4:55115342-55115342, 4:55118646-55118646, 4:55118742-55118743, 4:55121173-55121173, 4:55125291-55125291,	Info_not_available	0.5248, .53805, .55708, .56757, .56847, .56959, .59088, .59902, .6032, .6123, .66514, .66566, .68218, .68635, .69693, Info_not_available	28481359