Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
IGF1R	5465	COSM6975085,	urinary_tract	carcinoma	p.E979Q	Substitution - Missense	15:98930284-98930284,	PATHOGENIC	0.99886	28481359
IGF1R	5465	COSM6922617,	lung	carcinoma	p.E979K	Substitution - Missense	15:98930284-98930284,	PATHOGENIC	0.99866	28481359
IGF1R	5465	COSM6935850,	central_nervous_system	glioma	p.G970E	Substitution - Missense	15:98930258-98930258,	PATHOGENIC	0.99866	28481359
IGF1R	5465	COSM6937094,	thymus	thymic_carcinoma	p.R605S	Substitution - Missense	15:98913267-98913267,	PATHOGENIC	0.99833	28481359
IGF1R	5465	COSM6927869,	skin	carcinoma	p.E1097Q	Substitution - Missense	15:98935418-98935418,	PATHOGENIC	0.99811	28481359
IGF1R	5465	COSM4990824,	skin	carcinoma	p.G1067S	Substitution - Missense	15:98935328-98935328,	PATHOGENIC	0.99714	25589618
IGF1R	5465	COSM6983301,	upper_aerodigestive_tract	carcinoma	p.R605H	Substitution - Missense	15:98913268-98913268,	PATHOGENIC	0.99667	28481359
IGF1R	5465	COSM3969364,	salivary_gland	carcinoma	p.D555G	Substitution - Missense	15:98913118-98913118,	PATHOGENIC	0.99628	28481359
IGF1R	5465	COSM6855554,	soft_tissue	inflammatory_myofibroblastic_tumour	p.G545D	Substitution - Missense	15:98913088-98913088,	PATHOGENIC	0.99613	28481359
IGF1R	5465	COSM1375601,	urinary_tract	carcinoma	p.E1145K	Substitution - Missense	15:98939336-98939336,	PATHOGENIC	0.99601	28481359
IGF1R	5465	COSM6939003,	skin	carcinoma	p.D1086N	Substitution - Missense	15:98935385-98935385,	PATHOGENIC	0.99573	28481359
IGF1R	5465	COSM6920802,	central_nervous_system	glioma	p.G1085D	Substitution - Missense	15:98935383-98935383,	PATHOGENIC	0.99573	28481359
IGF1R	5465	COSM6909561,	urinary_tract	carcinoma	p.G912V	Substitution - Missense	15:98924637-98924637,	PATHOGENIC	0.9953	28481359
IGF1R	5465	COSM6940790,	large_intestine	carcinoma	p.?	Unknown	15:98911442-98911442,	PATHOGENIC	0.9952	28481359
IGF1R	5465	COSM6928449,	urinary_tract	carcinoma	p.R882K	Substitution - Missense	15:98924547-98924547,	PATHOGENIC	0.99474	28481359
IGF1R	5465	COSM6935489,	endometrium	carcinoma	p.T536A	Substitution - Missense	15:98913060-98913060,	PATHOGENIC	0.99466	28481359
IGF1R	5465	COSM6950770,	skin	malignant_melanoma	p.G899E	Substitution - Missense	15:98924598-98924598,	PATHOGENIC	0.99456	28481359
IGF1R	5465	COSM6967490,	upper_aerodigestive_tract	carcinoma	p.N913Y	Substitution - Missense	15:98924639-98924639,	PATHOGENIC	0.99381	28481359
IGF1R	5465	COSM6936955,	lung	carcinoma	p.E1162Q	Substitution - Missense	15:98942949-98942949,	PATHOGENIC	0.99363	28481359
IGF1R	5465	COSM6265817,	breast	carcinoma	p.D519Y	Substitution - Missense	15:98911407-98911407,	PATHOGENIC	0.99316	28481359
IGF1R	5465	COSM6919417,	soft_tissue	leiomyosarcoma	p.E1219K	Substitution - Missense	15:98948641-98948641,	PATHOGENIC	0.99316	28481359
IGF1R	5465	COSM6941379,	large_intestine	carcinoma	p.G1199R	Substitution - Missense	15:98948581-98948581,	PATHOGENIC	0.99316	28481359
IGF1R	5465	COSM6948527,	large_intestine	carcinoma	p.V1225I	Substitution - Missense	15:98948659-98948659,	PATHOGENIC	0.99316	28481359
IGF1R	5465	COSM5609105,	skin	malignant_melanoma	p.E779*	Substitution - Nonsense	15:98922281-98922281,	PATHOGENIC	0.99311	26343386
IGF1R	5465	COSM6935490,	endometrium	carcinoma	p.?	Unknown	15:98942922-98942922,	PATHOGENIC	0.99288	28481359
IGF1R	5465	COSM6971174,	skin	adnexal_tumour	p.M1012I	Substitution - Missense	15:98934903-98934903,	PATHOGENIC	0.99198	28481359
IGF1R	5465	COSM6944274,	large_intestine	carcinoma	p.G1016*	Substitution - Nonsense	15:98934913-98934913,	PATHOGENIC	0.99188	28481359
IGF1R	5465	COSM6915169,	lung	carcinoma	p.V1053L	Substitution - Missense	15:98935024-98935024,	PATHOGENIC	0.99182	28481359
IGF1R	5465	COSM6978801,	large_intestine	carcinoma	p.A530V	Substitution - Missense	15:98911441-98911441,	PATHOGENIC	0.99157	28481359
IGF1R	5465	COSM5850114,	lung	carcinoma	p.M1012I	Substitution - Missense	15:98934903-98934903,	PATHOGENIC	0.99095	28481359
IGF1R	5465	COSM1678707,	skin	malignant_melanoma	p.S915L	Substitution - Missense	15:98924646-98924646,	PATHOGENIC	0.99043	28481359
IGF1R	5465	COSM6907280,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.V1132I	Substitution - Missense	15:98939297-98939297,	PATHOGENIC	0.99036	28481359
IGF1R	5465	COSM6954829,	urinary_tract	carcinoma	p.K1111N	Substitution - Missense	15:98939236-98939236,	PATHOGENIC	0.99019	28481359
IGF1R	5465	COSM6947402,	pancreas	carcinoid-endocrine_tumour	p.S1197Y	Substitution - Missense	15:98948576-98948576,	PATHOGENIC	0.98999	28481359
IGF1R	5465	COSM6948605,	large_intestine	carcinoma	p.T1157A	Substitution - Missense	15:98942934-98942934,	PATHOGENIC	0.98955	28481359
IGF1R	5465	COSM6956333,	large_intestine	carcinoma	p.A1137V	Substitution - Missense	15:98939313-98939313,	PATHOGENIC	0.98946	28481359
IGF1R	5465	COSM48423,	lung	carcinoma	p.M1255I	Substitution - Missense	15:98957103-98957103,	PATHOGENIC	0.98638	18948947
IGF1R	5465	COSM6948219,	skin	malignant_melanoma	p.S1365W	Substitution - Missense	15:98957432-98957432,	PATHOGENIC	0.98529	28481359
IGF1R	5465	COSM6914603,	urinary_tract	carcinoma	p.M1255I	Substitution - Missense	15:98957103-98957103,	PATHOGENIC	0.98478	28481359
IGF1R	5465	COSM6967234,	lung	carcinoma	p.C303F	Substitution - Missense	15:98891592-98891592,	PATHOGENIC	0.98451	28481359
IGF1R	5465	COSM6962882,	skin	malignant_melanoma	p.P1181S	Substitution - Missense	15:98943006-98943006,	PATHOGENIC	0.98447	28481359
IGF1R	5465	COSM6964790,	kidney	carcinoma	p.N1252D	Substitution - Missense	15:98957092-98957092,	PATHOGENIC	0.98444	28481359
IGF1R	5465	COSM6981489,	large_intestine	carcinoma	p.A583D	Substitution - Missense	15:98913202-98913202,	PATHOGENIC	0.984	28481359
IGF1R	5465	COSM6913780,	skin	carcinoma	p.E786K	Substitution - Missense	15:98922302-98922302,	PATHOGENIC	0.98385	28481359
IGF1R	5465	COSM1578990,	large_intestine	carcinoma	p.V1303A	Substitution - Missense	15:98957246-98957246,	PATHOGENIC	0.98369	18186519
IGF1R	5465	COSM6924322,	lung	carcinoma	p.G1328V	Substitution - Missense	15:98957321-98957321,	PATHOGENIC	0.98356	28481359
IGF1R	5465	COSM6929390,	NS	malignant_melanoma	p.T587I	Substitution - Missense	15:98913214-98913214,	PATHOGENIC	0.98325	28481359
IGF1R	5465	COSM4058090,	skin	malignant_melanoma	p.G1328D	Substitution - Missense	15:98957321-98957321,	PATHOGENIC	0.98277	28481359
IGF1R	5465	COSM6962663,	large_intestine	carcinoma	p.P898L	Substitution - Missense	15:98924595-98924595,	PATHOGENIC	0.98168	28481359
IGF1R	5465	COSM1579001,	large_intestine	carcinoma	p.I1032T	Substitution - Missense	15:98934962-98934962,	PATHOGENIC	0.98155	18186519
IGF1R	5465	COSM6931278,	lung	carcinoma	p.W434S	Substitution - Missense	15:98908738-98908738,	PATHOGENIC	0.98086	28481359
IGF1R	5465	COSM20757,	kidney	carcinoma	p.Q1214*	Substitution - Nonsense	15:98948626-98948626,	PATHOGENIC	0.97973	20054297
IGF1R	5465	COSM20757,	kidney	carcinoma	p.Q1214*	Substitution - Nonsense	15:98948626-98948626,	PATHOGENIC	0.97973	20054297
IGF1R	5465	COSM6934370,	lung	carcinoma	p.R513L	Substitution - Missense	15:98911390-98911390,	PATHOGENIC	0.97853	28481359
IGF1R	5465	COSM6983475,	large_intestine	carcinoma	p.G310C	Substitution - Missense	15:98891612-98891612,	PATHOGENIC	0.97806	28481359
IGF1R	5465	COSM6974261,	lung	carcinoma	p.E177*	Substitution - Nonsense	15:98707996-98707996,	PATHOGENIC	0.97796	28481359
IGF1R	5465	COSM6974508,	breast	carcinoma	p.V821I	Substitution - Missense	15:98922407-98922407,	PATHOGENIC	0.97755	28481359
IGF1R	5465	COSM6979264,	large_intestine	carcinoma	p.W434*	Substitution - Nonsense	15:98908738-98908738,	PATHOGENIC	0.97745	28481359
IGF1R	5465	COSM6944769,	central_nervous_system	glioma	p.W434*	Substitution - Nonsense	15:98908739-98908739,	PATHOGENIC	0.97745	28481359
IGF1R	5465	COSM6949041,	urinary_tract	carcinoma	p.H804R	Substitution - Missense	15:98922357-98922357,	PATHOGENIC	0.97699	28481359
IGF1R	5465	COSM6909127,	urinary_tract	carcinoma	p.S309L	Substitution - Missense	15:98891610-98891610,	PATHOGENIC	0.97653	28481359
IGF1R	5465	COSM6922063,	pancreas	carcinoid-endocrine_tumour	p.R1357Q	Substitution - Missense	15:98957408-98957408,	PATHOGENIC	0.97641	28481359
IGF1R	5465	COSM6922063,	biliary_tract	carcinoma	p.R1357Q	Substitution - Missense	15:98957408-98957408,	PATHOGENIC	0.97641	28481359
IGF1R	5465	COSM6976351,	NS	malignant_melanoma	p.S612F	Substitution - Missense	15:98915970-98915970,	PATHOGENIC	0.97596	28481359
IGF1R	5465	COSM3505627,	skin	malignant_melanoma	p.P611S	Substitution - Missense	15:98915966-98915966,	PATHOGENIC	0.97596	26343386
IGF1R	5465	COSM6933126,	oesophagus	carcinoma	p.P855T	Substitution - Missense	15:98923953-98923953,	PATHOGENIC	0.97572	28481359
IGF1R	5465	COSM6924424,	lung	carcinoma	p.G483R	Substitution - Missense	15:98908884-98908884,	PATHOGENIC	0.97552	28481359
IGF1R	5465	COSM6924874,	lung	carcinoma	p.H727P	Substitution - Missense	15:98916855-98916855,	PATHOGENIC	0.97544	28481359
IGF1R	5465	COSM6976350,	NS	malignant_melanoma	p.A583V	Substitution - Missense	15:98913202-98913202,	PATHOGENIC	0.97505	28481359
IGF1R	5465	COSM6977385,	stomach	carcinoma	p.N728S	Substitution - Missense	15:98916858-98916858,	PATHOGENIC	0.97392	28481359
IGF1R	5465	COSM4990819,	skin	carcinoma	p.H299Y	Substitution - Missense	15:98891579-98891579,	PATHOGENIC	0.97363	25589618
IGF1R	5465	COSM6970578,	skin	malignant_melanoma	p.E1284K	Substitution - Missense	15:98957188-98957188,	PATHOGENIC	0.97363	28481359
IGF1R	5465	COSM6922126,	skin	malignant_melanoma	p.S623F	Substitution - Missense	15:98916003-98916003,	PATHOGENIC	0.97267	28481359
IGF1R	5465	COSM20745,	kidney	carcinoma	p.V105L	Substitution - Missense	15:98707780-98707780,	PATHOGENIC	0.97167	20054297
IGF1R	5465	COSM20745,	kidney	carcinoma	p.V105L	Substitution - Missense	15:98707780-98707780,	PATHOGENIC	0.97167	20054297
IGF1R	5465	COSM6920088,	large_intestine	carcinoma	p.D1294V	Substitution - Missense	15:98957219-98957219,	PATHOGENIC	0.97113	28481359
IGF1R	5465	COSM4990820,	skin	carcinoma	p.P308L	Substitution - Missense	15:98891607-98891607,	PATHOGENIC	0.96909	25589618
IGF1R	5465	COSM1578989,	penis	carcinoma	p.D679N	Substitution - Missense	15:98916710-98916710,	PATHOGENIC	0.96904	28481359
IGF1R	5465	COSM1578989,	large_intestine	carcinoma	p.D679N	Substitution - Missense	15:98916710-98916710,	PATHOGENIC	0.96904	18186519
IGF1R	5465	COSM6952999,	stomach	carcinoma	p.T466K	Substitution - Missense	15:98908834-98908834,	PATHOGENIC	0.96894	28481359
IGF1R	5465	COSM6978627,	skin	malignant_melanoma	p.S664C	Substitution - Missense	15:98916126-98916126,	PATHOGENIC	0.96834	28481359
IGF1R	5465	COSM6964582,	large_intestine	carcinoma	p.G565C	Substitution - Missense	15:98913147-98913147,	PATHOGENIC	0.96753	28481359
IGF1R	5465	COSM6957561,	penis	carcinoma	p.P35T	Substitution - Missense	15:98707570-98707570,	PATHOGENIC	0.96738	28481359
IGF1R	5465	COSM6929923,	kidney	carcinoma	p.S612P	Substitution - Missense	15:98915969-98915969,	PATHOGENIC	0.96705	28481359
IGF1R	5465	COSM198954,	large_intestine	carcinoma	p.G108S	Substitution - Missense	15:98707789-98707789,	PATHOGENIC	0.96661	28481359
IGF1R	5465	COSM6954496,	large_intestine	carcinoma	p.E121K	Substitution - Missense	15:98707828-98707828,	PATHOGENIC	0.96661	28481359
IGF1R	5465	COSM6912118,	skin	malignant_melanoma	p.L1222F	Substitution - Missense	15:98948650-98948650,	PATHOGENIC	0.96627	28481359
IGF1R	5465	COSM12856,	lung	carcinoma	p.A1347V	Substitution - Missense	15:98957378-98957378,	PATHOGENIC	0.96621	16140923
IGF1R	5465	COSM12856,	lung	carcinoma	p.A1347V	Substitution - Missense	15:98957378-98957378,	PATHOGENIC	0.96621	16140923
IGF1R	5465	COSM6939569,	breast	carcinoma	p.S1339C	Substitution - Missense	15:98957353-98957353,	PATHOGENIC	0.96533	28481359
IGF1R	5465	COSM6937932,	urinary_tract	carcinoma	p.P1026H	Substitution - Missense	15:98934944-98934944,	PATHOGENIC	0.96497	28481359
IGF1R	5465	COSM3706835,	breast	carcinoma	p.E809K	Substitution - Missense	15:98922371-98922371,	PATHOGENIC	0.96315	28481359
IGF1R	5465	COSM6960298,	breast	carcinoma	p.T466M	Substitution - Missense	15:98908834-98908834,	PATHOGENIC	0.9631	28481359
IGF1R	5465	COSM4990821,	skin	carcinoma	p.R595C	Substitution - Missense	15:98913237-98913237,	PATHOGENIC	0.96285	25589618
IGF1R	5465	COSM6963242,	skin	malignant_melanoma	p.P858S	Substitution - Missense	15:98923962-98923962,	PATHOGENIC	0.96252	28481359
IGF1R	5465	COSM3741744,	lung	carcinoma	p.K194N	Substitution - Missense	15:98708049-98708049,	PATHOGENIC	0.96228	28481359
IGF1R	5465	COSM4399322,	skin	malignant_melanoma	p.R504C	Substitution - Missense	15:98911362-98911362,	PATHOGENIC	0.96192	28481359
IGF1R	5465	COSM4399322,	skin	malignant_melanoma	p.R504C	Substitution - Missense	15:98911362-98911362,	PATHOGENIC	0.96192	28481359
IGF1R	5465	COSM6959522,	central_nervous_system	glioma	p.P1307L	Substitution - Missense	15:98957258-98957258,	PATHOGENIC	0.95851	28481359
IGF1R	5465	COSM6956471,	skin	malignant_melanoma	p.M1270R	Substitution - Missense	15:98957147-98957147,	PATHOGENIC	0.95679	28481359
IGF1R	5465	COSM6943793,	lung	carcinoma	p.Y673C	Substitution - Missense	15:98916693-98916693,	PATHOGENIC	0.95658	28481359
IGF1R	5465	COSM6977483,	stomach	carcinoma	p.G379W	Substitution - Missense	15:98899509-98899509,	PATHOGENIC	0.95631	28481359
IGF1R	5465	COSM6968727,	lung	carcinoma	p.I594V	Substitution - Missense	15:98913234-98913234,	PATHOGENIC	0.95539	28481359
IGF1R	5465	COSM6961674,	large_intestine	carcinoma	p.G949R	Substitution - Missense	15:98929620-98929620,	PATHOGENIC	0.95368	28481359
IGF1R	5465	COSM6963522,	skin	carcinoma	p.P183L	Substitution - Missense	15:98708015-98708015,	PATHOGENIC	0.95361	28481359
IGF1R	5465	COSM6931226,	skin	malignant_melanoma	p.S95N	Substitution - Missense	15:98707751-98707751,	PATHOGENIC	0.95345	28481359
IGF1R	5465	COSM6966687,	stomach	carcinoma	p.D280V	Substitution - Missense	15:98891523-98891523,	PATHOGENIC	0.95242	28481359
IGF1R	5465	COSM6911140,	urinary_tract	carcinoma	p.K502N	Substitution - Missense	15:98911358-98911358,	PATHOGENIC	0.95221	28481359
IGF1R	5465	COSM6917209,	skin	malignant_melanoma	p.P776S	Substitution - Missense	15:98922272-98922272,	PATHOGENIC	0.94972	28481359
IGF1R	5465	COSM6953224,	NS	malignant_melanoma	p.Y930C	Substitution - Missense	15:98929564-98929564,	PATHOGENIC	0.94949	28481359
IGF1R	5465	COSM3670182,	salivary_gland	carcinoma	p.F933C	Substitution - Missense	15:98929573-98929573,	PATHOGENIC	0.94867	28481359
IGF1R	5465	COSM6918942,	prostate	carcinoma	p.E68K	Substitution - Missense	15:98707669-98707669,	PATHOGENIC	0.94865	28481359
IGF1R	5465	COSM6914679,	skin	malignant_melanoma	p.P76S	Substitution - Missense	15:98707693-98707693,	PATHOGENIC	0.94762	28481359
IGF1R	5465	COSM6927193,	lung	carcinoma	p.N369S	Substitution - Missense	15:98899480-98899480,	PATHOGENIC	0.94567	28481359
IGF1R	5465	COSM6927193,	urinary_tract	carcinoma	p.N369S	Substitution - Missense	15:98899480-98899480,	PATHOGENIC	0.94567	28481359
IGF1R	5465	COSM6967795,	urinary_tract	carcinoma	p.H959Y	Substitution - Missense	15:98929650-98929650,	PATHOGENIC	0.94464	28481359
IGF1R	5465	COSM1678705,	urinary_tract	carcinoma	p.R107H	Substitution - Missense	15:98707787-98707787,	PATHOGENIC	0.94347	28481359
IGF1R	5465	COSM6927639,	central_nervous_system	glioma	p.R406H	Substitution - Missense	15:98899591-98899591,	PATHOGENIC	0.94345	28481359
IGF1R	5465	COSM6913018,	lung	carcinoma	p.N550K	Substitution - Missense	15:98913104-98913104,	PATHOGENIC	0.94307	28481359
IGF1R	5465	COSM6967983,	kidney	carcinoma	p.Q1250H	Substitution - Missense	15:98957088-98957088,	PATHOGENIC	0.94163	28481359
IGF1R	5465	COSM6958377,	lung	carcinoma	p.E463D	Substitution - Missense	15:98908826-98908826,	PATHOGENIC	0.9408	28481359
IGF1R	5465	COSM6942787,	large_intestine	carcinoma	p.Q906R	Substitution - Missense	15:98924619-98924619,	PATHOGENIC	0.9401	28481359
IGF1R	5465	COSM6914574,	prostate	carcinoma	p.N404H	Substitution - Missense	15:98899584-98899584,	PATHOGENIC	0.93937	28481359
IGF1R	5465	COSM6927147,	breast	carcinoma	p.S1089R	Substitution - Missense	15:98935396-98935396,	PATHOGENIC	0.93851	28481359
IGF1R	5465	COSM6947972,	lung	carcinoma	p.E1276D	Substitution - Missense	15:98957166-98957166,	PATHOGENIC	0.93797	28481359
IGF1R	5465	COSM6927297,	urinary_tract	carcinoma	p.E811K	Substitution - Missense	15:98922377-98922377,	PATHOGENIC	0.93721	28481359
IGF1R	5465	COSM6934756,	breast	carcinoma	p.M304I	Substitution - Missense	15:98891596-98891596,	PATHOGENIC	0.93533	28481359
IGF1R	5465	COSM6922866,	NS	malignant_melanoma	p.E770K	Substitution - Missense	15:98922254-98922254,	PATHOGENIC	0.93517	28481359
IGF1R	5465	COSM1678708,	endometrium	carcinoma	p.R1246C	Substitution - Missense	15:98957074-98957074,	PATHOGENIC	0.9328	28481359
IGF1R	5465	COSM1678708,	skin	carcinoma	p.R1246C	Substitution - Missense	15:98957074-98957074,	PATHOGENIC	0.9328	28481359
IGF1R	5465	COSM6910944,	skin	adnexal_tumour	p.R996W	Substitution - Missense	15:98934853-98934853,	PATHOGENIC	0.93037	28481359
IGF1R	5465	COSM6943293,	urinary_tract	carcinoma	p.Q653*	Substitution - Nonsense	15:98916092-98916092,	PATHOGENIC	0.92962	28481359
IGF1R	5465	COSM6971472,	stomach	carcinoma	p.A1338T	Substitution - Missense	15:98957350-98957350,	PATHOGENIC	0.92853	28481359
IGF1R	5465	COSM6961970,	pancreas	carcinoid-endocrine_tumour	p.L910F	Substitution - Missense	15:98924630-98924630,	PATHOGENIC	0.92807	28481359
IGF1R	5465	COSM311930,	lung	carcinoma	p.R787I	Substitution - Missense	15:98922306-98922306,	PATHOGENIC	0.92499	22941188
IGF1R	5465	COSM6912401,	lung	carcinoma	p.Y869S	Substitution - Missense	15:98923996-98923996,	PATHOGENIC	0.92406	28481359
IGF1R	5465	COSM6972042,	ovary	carcinoma	p.R1003W	Substitution - Missense	15:98934874-98934874,	PATHOGENIC	0.92137	28481359
IGF1R	5465	COSM6935849,	central_nervous_system	glioma	p.E463K	Substitution - Missense	15:98908824-98908824,	PATHOGENIC	0.92017	28481359
IGF1R	5465	COSM6908696,	stomach	carcinoma	p.D1153E	Substitution - Missense	15:98942924-98942924,	PATHOGENIC	0.91939	28481359
IGF1R	5465	COSM6913971,	oesophagus	carcinoma	p.R71H	Substitution - Missense	15:98707679-98707679,	PATHOGENIC	0.91786	28481359
IGF1R	5465	COSM6973634,	large_intestine	carcinoma	p.V721I	Substitution - Missense	15:98916836-98916836,	PATHOGENIC	0.91756	28481359
IGF1R	5465	COSM6977885,	breast	carcinoma	p.E708D	Substitution - Missense	15:98916799-98916799,	PATHOGENIC	0.91718	28481359
IGF1R	5465	COSM6945849,	NS	carcinoma	p.R71L	Substitution - Missense	15:98707679-98707679,	PATHOGENIC	0.9143	28481359
IGF1R	5465	COSM5609107,	skin	malignant_melanoma	p.S400F	Substitution - Missense	15:98899573-98899573,	PATHOGENIC	0.9108	26343386
IGF1R	5465	COSM6980141,	lung	carcinoma	p.R781T	Substitution - Missense	15:98922288-98922288,	PATHOGENIC	0.9087	28481359
IGF1R	5465	COSM1578978,	large_intestine	carcinoma	p.A371D	Substitution - Missense	15:98899486-98899486,	PATHOGENIC	0.90819	18186519
IGF1R	5465	COSM6937933,	urinary_tract	carcinoma	p.F1047L	Substitution - Missense	15:98935008-98935008,	PATHOGENIC	0.90596	28481359
IGF1R	5465	COSM5609106,	skin	malignant_melanoma	p.F1259F	Substitution - coding silent	15:98957115-98957115,	PATHOGENIC	0.90562	26343386
IGF1R	5465	COSM6917344,	large_intestine	carcinoma	p.Y70H	Substitution - Missense	15:98707675-98707675,	PATHOGENIC	0.90218	28481359
IGF1R	5465	COSM3505634,	stomach	carcinoma	p.R1337C	Substitution - Missense	15:98957347-98957347,	PATHOGENIC	0.89933	26489445
IGF1R	5465	COSM6972621,	breast	carcinoma	p.R1092W	Substitution - Missense	15:98935403-98935403,	PATHOGENIC	0.89182	28481359
IGF1R	5465	COSM6946578,	biliary_tract	carcinoma	p.V957F	Substitution - Missense	15:98929644-98929644,	PATHOGENIC	0.89152	28481359
IGF1R	5465	COSM6952998,	stomach	carcinoma	p.D292G	Substitution - Missense	15:98891559-98891559,	PATHOGENIC	0.89104	28481359
IGF1R	5465	COSM6684184,	central_nervous_system	glioma	p.R719H	Substitution - Missense	15:98916831-98916831,	PATHOGENIC	0.88644	28481359
IGF1R	5465	COSM6959863,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T466A	Substitution - Missense	15:98908833-98908833,	PATHOGENIC	0.8789	28481359
IGF1R	5465	COSM6930896,	central_nervous_system	glioma	p.G326V	Substitution - Missense	15:98896780-98896780,	PATHOGENIC	0.8772	28481359
IGF1R	5465	COSM6957562,	penis	carcinoma	p.E188K	Substitution - Missense	15:98708029-98708029,	PATHOGENIC	0.87399	28481359
IGF1R	5465	COSM6977823,	urinary_tract	carcinoma	p.E856Q	Substitution - Missense	15:98923956-98923956,	PATHOGENIC	0.87271	28481359
IGF1R	5465	COSM6908714,	urinary_tract	carcinoma	p.S65C	Substitution - Missense	15:98707661-98707661,	PATHOGENIC	0.86808	28481359
IGF1R	5465	COSM966778,	endometrium	carcinoma	p.R406C	Substitution - Missense	15:98899590-98899590,	PATHOGENIC	0.85394	28481359
IGF1R	5465	COSM966778,	large_intestine	carcinoma	p.R406C	Substitution - Missense	15:98899590-98899590,	PATHOGENIC	0.85394	28481359
IGF1R	5465	COSM966778,	endometrium	carcinoma	p.R406C	Substitution - Missense	15:98899590-98899590,	PATHOGENIC	0.85394	28481359
IGF1R	5465	COSM4058076,	large_intestine	carcinoma	p.E226K	Substitution - Missense	15:98891360-98891360,	PATHOGENIC	0.84823	28481359
IGF1R	5465	COSM6980050,	lung	carcinoma	p.M378V	Substitution - Missense	15:98899506-98899506,	PATHOGENIC	0.84575	28481359
IGF1R	5465	COSM6975610,	soft_tissue	angiosarcoma	p.S72G	Substitution - Missense	15:98707681-98707681,	PATHOGENIC	0.83489	28481359
IGF1R	5465	COSM5609108,	skin	malignant_melanoma	p.F958F	Substitution - coding silent	15:98929649-98929649,	PATHOGENIC	0.82257	26343386
IGF1R	5465	COSM6918242,	large_intestine	carcinoma	p.T788I	Substitution - Missense	15:98922309-98922309,	PATHOGENIC	0.81839	28481359
IGF1R	5465	COSM5019957,	soft_tissue	haemangioblastoma	p.G416E	Substitution - Missense	15:98899621-98899621,	PATHOGENIC	0.81608	25589003
IGF1R	5465	COSM6936193,	breast	carcinoma	p.E94D	Substitution - Missense	15:98707749-98707749,	PATHOGENIC	0.81258	28481359
IGF1R	5465	COSM6919326,	large_intestine	carcinoma	p.D1341N	Substitution - Missense	15:98957359-98957359,	PATHOGENIC	0.81041	28481359
IGF1R	5465	COSM311929,	lung	carcinoma	p.R471C	Substitution - Missense	15:98908848-98908848,	PATHOGENIC	0.80916	22941188
IGF1R	5465	COSM287535,	stomach	carcinoma	p.R252H	Substitution - Missense	15:98891439-98891439,	PATHOGENIC	0.80671	28481359
IGF1R	5465	COSM6922773,	lung	carcinoma	p.E188D	Substitution - Missense	15:98708031-98708031,	PATHOGENIC	0.80199	28481359
IGF1R	5465	COSM5020668,	soft_tissue	haemangioblastoma	p.F75F	Substitution - coding silent	15:98707692-98707692,	PATHOGENIC	0.8007	25589003
IGF1R	5465	COSM6967091,	urinary_tract	carcinoma	p.R1275W	Substitution - Missense	15:98957161-98957161,	PATHOGENIC	0.79486	28481359
IGF1R	5465	COSM702041,	large_intestine	carcinoma	p.R595H	Substitution - Missense	15:98913238-98913238,	PATHOGENIC	0.79145	18186519
IGF1R	5465	COSM6928101,	oesophagus	carcinoma	p.T385R	Substitution - Missense	15:98899528-98899528,	PATHOGENIC	0.79125	28481359
IGF1R	5465	COSM6934481,	endometrium	carcinoma	p.A701T	Substitution - Missense	15:98916776-98916776,	PATHOGENIC	0.7862	28481359
IGF1R	5465	COSM6936729,	large_intestine	carcinoma	p.V492I	Substitution - Missense	15:98911326-98911326,	PATHOGENIC	0.77533	28481359
IGF1R	5465	COSM5520229,	soft_tissue	liposarcoma	p.G315S	Substitution - Missense	15:98891627-98891627,	PATHOGENIC	0.73514	28481359
IGF1R	5465	COSM6958046,	biliary_tract	carcinoma	p.R480S	Substitution - Missense	15:98908877-98908877,	PATHOGENIC	0.72961	28481359
IGF1R	5465	COSM6927018,	large_intestine	carcinoma	p.V1303I	Substitution - Missense	15:98957245-98957245,	PATHOGENIC	0.72271	28481359
IGF1R	5465	COSM3402036,	skin	malignant_melanoma	p.P174P	Substitution - coding silent	15:98707989-98707989,	PATHOGENIC	0.72251	26343386
IGF1R	5465	COSM6940441,	urinary_tract	carcinoma	p.L863I	Substitution - Missense	15:98923977-98923977,	PATHOGENIC	0.71985	28481359
IGF1R	5465	COSM1678706,	prostate	carcinoma	p.R365L	Substitution - Missense	15:98896897-98896897,	PATHOGENIC	0.70698	28481359
IGF1R	5465	COSM6944412,	large_intestine	carcinoma	p.D675N	Substitution - Missense	15:98916698-98916698,	PATHOGENIC	0.70526	28481359
IGF1R	5465	COSM1578979,	large_intestine	carcinoma	p.P1317P	Substitution - coding silent	15:98957289-98957289,	NEUTRAL	0.48632	18186519
IGF1R	5465	COSM6960011,	large_intestine	carcinoma	p.R753*	Substitution - Nonsense	15:98922203-98922203,	NEUTRAL	0.46813	28481359
IGF1R	5465	COSM6961367,	prostate	carcinoma	p.P853T	Substitution - Missense	15:98923947-98923947,	NEUTRAL	0.44802	28481359
IGF1R	5465	COSM5020666,	soft_tissue	haemangioblastoma	p.N638N	Substitution - coding silent	15:98916049-98916049,	NEUTRAL	0.43383	25589003
IGF1R	5465	COSM6981659,	large_intestine	carcinoma	p.K887N	Substitution - Missense	15:98924563-98924563,	NEUTRAL	0.42174	28481359
IGF1R	5465	COSM6959906,	breast	carcinoma	p.S1282R	Substitution - Missense	15:98957184-98957184,	NEUTRAL	0.36618	28481359
IGF1R	5465	COSM6942267,	urinary_tract	carcinoma	p.S24L	Substitution - Missense	15:98649652-98649652,	NEUTRAL	0.35441	28481359
IGF1R	5465	COSM48422,	lung	carcinoma	p.I364M	Substitution - Missense	15:98896895-98896895,	NEUTRAL	0.33555	18948947
IGF1R	5465	COSM4770095,	soft_tissue	haemangioblastoma	p.T766T	Substitution - coding silent	15:98922244-98922244,	NEUTRAL	0.29458	25589003
IGF1R	5465	COSM4770095,	soft_tissue	haemangioblastoma	p.T766T	Substitution - coding silent	15:98922244-98922244,	NEUTRAL	0.29458	25589003
IGF1R	5465	COSM3754596,	soft_tissue	haemangioblastoma	p.G301G	Substitution - coding silent	15:98891587-98891587,	NEUTRAL	0.25932	25589003
IGF1R	5465	COSM6960815,	large_intestine	carcinoma	p.P558S	Substitution - Missense	15:98913126-98913126,	NEUTRAL	0.21845	28481359
IGF1R	5465	COSM6923560,	large_intestine	carcinoma	p.A1105S	Substitution - Missense	15:98939216-98939216,	NEUTRAL	0.21707	28481359
IGF1R	5465	COSM6935488,	endometrium	carcinoma	p.F18L	Substitution - Missense	15:98649633-98649633,	NEUTRAL	0.21663	28481359
IGF1R	5465	COSM6919170,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S12L	Substitution - Missense	15:98649616-98649616,	NEUTRAL	0.20005	28481359
IGF1R	5465	COSM6919170,	urinary_tract	carcinoma	p.S12L	Substitution - Missense	15:98649616-98649616,	NEUTRAL	0.20005	28481359
IGF1R	5465	COSM6927726,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R366Q	Substitution - Missense	15:98896900-98896900,	NEUTRAL	0.19156	28481359
IGF1R	5465	COSM6946472,	large_intestine	carcinoma	p.A257V	Substitution - Missense	15:98891454-98891454,	NEUTRAL	0.15829	28481359
IGF1R	5465	COSM5609109,	skin	malignant_melanoma	p.I628I	Substitution - coding silent	15:98916019-98916019,	NEUTRAL	0.14999	26343386
IGF1R	5465	COSM5020636,	soft_tissue	haemangioblastoma	p.A288A	Substitution - coding silent	15:98891548-98891548,	NEUTRAL	0.14635	25589003
IGF1R	5465	COSM6937931,	urinary_tract	carcinoma	p.S293F	Substitution - Missense	15:98891562-98891562,	NEUTRAL	0.13893	28481359
IGF1R	5465	COSM1608871,	liver	carcinoma	p.S240N	Substitution - Missense	15:98891403-98891403,	NEUTRAL	0.1157	Info_not_available
IGF1R	5465	COSM4990822,	skin	carcinoma	p.Q744Q	Substitution - coding silent	15:98922178-98922178,	NEUTRAL	0.11265	25589618
IGF1R	5465	COSM6946333,	large_intestine	carcinoma	p.S501L	Substitution - Missense	15:98911354-98911354,	NEUTRAL	0.09903	28481359
IGF1R	5465	COSM4990825,	skin	carcinoma	p.P1329P	Substitution - coding silent	15:98957325-98957325,	NEUTRAL	0.02938	25589618
IGF1R	5465	COSM21327,	kidney	carcinoma	p.S1278delS	Deletion - In frame	15:98957171-98957173,	Info_not_available	Info_not_available	20054297
IGF1R	5465	COSM5751590, COSM5751902,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1219fs*21, p.E1342fs*>27	Complex - frameshift	15:98948641-98948641, 15:98957362-98957362,	Info_not_available	Info_not_available	26206799
IGF1R	5465	COSM1579048,	breast	carcinoma	p.Y1346Y	Substitution - coding silent	15:98957376-98957376,	Info_not_available	0.68707	18186519
IGF1R	5465	COSM1579048, COSM3738001,	soft_tissue	haemangioblastoma	p.R437H, p.Y1346Y	Substitution - Missense, Substitution - coding silent	15:98908747-98908747, 15:98957376-98957376,	Info_not_available	0.68255, .68707	25589003
IGF1R	5465	COSM4990823,	skin	carcinoma	p.V1013V	Substitution - coding silent	15:98934906-98934906,	Info_not_available	0.67739	25589618
IGF1R	5465	COSM5609110, COSM5611307, COSM5611308,	skin	malignant_melanoma	p.P101S, p.P531L, p.S487S	Substitution - Missense, Substitution - coding silent	15:98707767-98707768, 15:98908898-98908898, 15:98913046-98913047,	Info_not_available	0.54578, Info_not_available	26343386
IGF1R	5465	COSM2141416, COSM371768, COSM6684198, COSM6684204, COSM6910674, COSM6917898, COSM6917982, COSM6923902, COSM6927892, COSM6931995, COSM6932998, COSM6933802, COSM6934144, COSM6937106, COSM6941649, COSM6941942, COSM6945033, COSM6958064, COSM6961610, COSM6961969, COSM6970998, COSM6971579, COSM6971808, COSM6975686, COSM6978580, COSM6987148,	NS, breast, central_nervous_system, haematopoietic_and_lymphoid_tissue, large_intestine, lung, pancreas, salivary_gland, skin, stomach, testis, upper_aerodigestive_tract, urinary_tract	carcinoid-endocrine_tumour, carcinoma, germ_cell_tumour, glioma, lymphoid_neoplasm, malignant_melanoma	p.?, p.A1039_R1042>CFC, p.D1318G, p.D666_K667insRHNYCSKD, p.D918fs*19, p.F420delF, p.G108fs*15, p.G237V, p.G367E, p.G912fs*26, p.K665_D666ins12, p.L19fs*27, p.M1098delM, p.M319fs*66, p.N368fs*17, p.N404fs*66, p.N661K, p.P233S, p.P262S, p.R1044_I1045insM, p.R781K, p.S1197F, p.S1311L, p.S217N, p.S5R	Complex - deletion inframe, Complex - frameshift, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Insertion - In frame, Substitution - Missense, Unknown	15:98649594-98649595, 15:98649635-98649638, 15:98649675-98649678, 15:98707377-98707620, 15:98707788-98707789, 15:98891334-98891334, 15:98891381-98891381, 15:98891394-98891395, 15:98891468-98891468, 15:98896760-98896760, 15:98896900-98896900, 15:98896903-98896903, 15:98899579-98899580, 15:98908694-98908696, 15:98916097-98916098, 15:98916107-98916108, 15:98916118-98916118, 15:98922288-98922288, 15:98924626-98924627, 15:98924654-98924654, 15:98934982-98934991, 15:98934998-98934999, 15:98935420-98935422, 15:98948576-98948577, 15:98957270-98957270, 15:98957291-98957291,	Info_not_available	0.51419, .61752, .65259, .67272, .67445, .68077, .69687, .69809, Info_not_available	28481359