Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
ABL1	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Far Western, Reconstituted Complex, experimental interaction detection	phosphorylation reaction, physical	10829062, 11494134, 12475393, 14604282, 14725908, 15556646, 16955467, 19380743, 19823681, 20675402, 8626543, 9174058, 9195915	0.31	BioGRID, IntAct, MINT
ARHGEF7	Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down	physical, physical association	12935897, 14505571, 16407834, 22588125, 23175185	0.59	BioGRID, IntAct, MINT
ASAP1	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	17255943	0.40	BioGRID, IntAct, MINT
BLK	Affinity Capture-Western, coimmunoprecipitation	physical, physical association	8621719	0.40	BioGRID, IntAct, MINT
CD2AP	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, imaging technique, pull down	association, direct interaction, physical, physical association	11067845, 12559036, 12618476, 12672817, 15128873, 17020880, 17072306, 17188587, 22706086, 25036637, 25872741	0.80	BioGRID, IntAct, MINT
CRK	Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, pull down, tandem affinity purification, two hybrid array, validated two hybrid	association, physical, physical association	10962563, 11792427, 12393469, 15581361, 16289966, 18835194, 19380743, 22974441, 25814554, 8524328, 8621483, 8626404, 8626543, 8662998, 8683103, 8943292, 9129019, 9178909, 9416834, 9461587, 9617486, 9988765	0.49, 0.88	BioGRID, IntAct, MINT
CRKL	Affinity Capture-MS, Affinity Capture-Western, Far Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection, far western blotting, pull down, two hybrid array	association, physical, physical association	10204582, 10608804, 10657627, 10907644, 11133830, 11157475, 11263968, 11399323, 11553620, 12244174, 14604282, 15107835, 15358160, 15556646, 16503409, 16982329, 18835194, 24886428, 25814554, 7545163, 8524328, 8626543, 8662998, 9092574, 9129019, 9162067, 9195915, 9311917, 9344843, 9461587, 9590251, 9820532, 9851874, 9988765	0.83	BioGRID, IntAct, MINT
EGFR	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, far western blotting, fluorescence microscopy, isothermal titration calorimetry, pull down, x-ray crystallography	association, colocalization, direct interaction, physical, physical association	10086340, 10428778, 10635327, 11239464, 11370743, 11408594, 12061819, 12593795, 12604776, 12734385, 12803489, 14505571, 14627991, 15107835, 15117950, 15159412, 15210722, 15282549, 15383614, 15465819, 15657067, 15668240, 15677445, 15735736, 15962011, 16105874, 16246327, 16729043, 16849543, 16914641, 16923119, 16969069, 17182860, 17242169, 17486068, 17545148, 17880946, 17971399, 17995934, 18271526, 18273061, 18316398, 18508924, 19155296, 19225046, 19531499, 19578043, 19713535, 19836242, 19947936, 20124286, 20308550, 20562913, 20877636, 20940296, 21772844, 22203672, 22266821, 22394513, 22591401, 22833562, 22976291, 23153581, 23158001, 23175185, 23418353, 23457600, 23774213, 23799367, 23897813, 24714105, 24797263, 25140053, 25521828, 25872741, 26055326, 26177020, 27059931, 28198003, 28791635, 7592693, 7657591, 7782294, 8662998, 9121472, 9130710, 9756944	0.96	BioGRID, IntAct, MINT
FCGR1A	experimental interaction detection	phosphorylation reaction	9716598	0.31	IntAct, MINT
FLT1	Affinity Capture-Western, isothermal titration calorimetry	direct interaction, physical	18273061, 25387128	0.44	BioGRID, IntAct, MINT
FYN	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, competition binding, experimental interaction detection, pull down, two hybrid array	phosphorylation reaction, physical, physical association	10629042, 10829062, 12231245, 12244174, 12941616, 15190072, 15208330, 15556646, 16503409, 17094785, 25814554, 7642581, 7782294, 8621719, 8626543, 8662998, 8900205, 8995358, 9311917, 9535867	0.37, 0.80	BioGRID, IntAct, MINT
GRB2	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Co-purification, FRET, Far Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, competition binding, isothermal titration calorimetry, luminescence based mammalian interactome mapping, pull down, tandem affinity purification, two hybrid array, two hybrid pooling approach	association, direct interaction, physical, physical association	10025673, 10086340, 10204582, 10521482, 10570290, 10829062, 11263968, 11399323, 11792427, 11823423, 11964172, 11997436, 12839496, 12941616, 14725908, 15210722, 15677445, 16906159, 17072306, 17094785, 17944804, 17971399, 18273061, 19380743, 19836242, 20124286, 20936779, 21706016, 23799367, 25036637, 25814554, 25872741, 28514442, 7537740, 7592693, 7642581, 7791764, 8083187, 8621719, 8626404, 8649804, 8662998, 8695851, 8824292, 8900205, 8943292, 8950973, 8995358, 9092538, 9108392, 9129019, 9174058, 9178909, 9233773, 9234717, 9242692, 9259313, 9311917, 9367879, 9434624, 9461587, 9541596, 9716598, 9851874, 9872323	0.44, 0.96	BioGRID, IntAct, MINT
ITCH	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	12226085, 19341794	0.40	BioGRID, IntAct, MINT
ITSN1	Affinity Capture-Western, Far Western, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, far western blotting, fluorescence microscopy, pull down, two hybrid	colocalization, physical, physical association	16914641, 18539136, 18654987, 21712076	0.73	BioGRID, IntAct, MINT
LCK	Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, pull down	direct interaction, physical, physical association	11904433, 16107303, 7721825, 8621719, 8626543, 8900205	0.75	BioGRID, IntAct, MINT
LCP2	Affinity Capture-Western, coimmunoprecipitation	physical, physical association	10204582, 10477741, 19635790, 9716598	0.40	BioGRID, IntAct, MINT
LYN	Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation	physical, physical association	12244174, 15190072, 18235045, 7721825, 7782294, 8621719, 9160881	0.40	BioGRID, IntAct, MINT
MAPK8	Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation	physical, physical association	11944898, 16982329	0.40	BioGRID, IntAct, MINT
MET	Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Co-localization, Far Western, Reconstituted Complex, anti bait coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection, isothermal titration calorimetry, mass spectrometry studies of complexes, proximity ligation assay, surface plasmon resonance, x-ray crystallography	direct interaction, physical, physical association, ubiquitination reaction	11894096, 15123609, 16397241, 18273061, 19433454, 19450681, 21163258, 21222362, 25241761	0.86	BioGRID, IntAct, MINT
MST1R	Affinity Capture-Western, isothermal titration calorimetry	direct interaction, physical	12802274, 16740632, 18273061	0.44	BioGRID, IntAct, MINT
NCK1	Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, phage display, pull down	direct interaction, physical, physical association	10204582, 10372803, 10829062, 10967110, 11494134, 16503409, 24287595, 7517397, 9851874	0.61	BioGRID, IntAct, MINT
NTRK1	Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	21570973, 25921289	0.40	BioGRID, IntAct, MINT
PDGFRB	coimmunoprecipitation	association	17620338	0.35	IntAct, MINT
PIK3R1	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Far Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection, far western blotting, pull down, tandem affinity purification, two hybrid, two hybrid array, validated two hybrid	association, physical, physical association	10025673, 10358153, 10620516, 10918571, 11030146, 11042121, 11087752, 11157475, 11418612, 11944898, 11994282, 14530346, 15107835, 15556646, 15581361, 16135792, 16219545, 16289966, 16982329, 17237826, 18374639, 19190244, 19380743, 19861161, 21203488, 24113870, 25814554, 7642581, 7791764, 8612729, 8621719, 8662998, 8695807, 8702998, 8896416, 8941725, 8995243, 9092538, 9160881, 9174058, 9259313, 9414268, 9461587, 9541596, 9890943, 9890970, 9918857, 9988765	0.49, 0.94	BioGRID, IntAct, MINT
PTPN22	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	10068674	0.40	BioGRID, IntAct, MINT
RET	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down	physical, physical association	12727845, 15677445	0.70	BioGRID, IntAct, MINT
SFN	Affinity Capture-Western, biochemical	association, physical	11697890	0.35	BioGRID, IntAct, MINT
SH2B2	Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, anti tag coimmunoprecipitation, isothermal titration calorimetry, pull down	association, direct interaction, physical, physical association	10374881, 15737992, 17620296, 18273061, 9989826	0.66	BioGRID, IntAct, MINT
SH3GL2	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical, physical association	11894095	0.50	BioGRID, IntAct, MINT
SH3KBP1	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Co-fractionation, Reconstituted Complex, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, isothermal titration calorimetry, nuclear magnetic resonance, pull down, two hybrid	association, direct interaction, physical, physical association	10679202, 11071869, 11152963, 11894095, 11894096, 12135478, 12177062, 12618476, 12874286, 14596919, 15090612, 15107835, 15456872, 15962011, 16228008, 16407834, 17072306, 17306257, 17675467, 19268472, 19417776, 19531213, 20130058, 20711168, 21830225, 22262777, 22833562, 24167568, 25036637, 25472714, 28514442	0.97	BioGRID, IntAct, MINT
SHC1	Affinity Capture-MS, Affinity Capture-Western, coimmunoprecipitation, pull down, tandem affinity purification	association, physical, physical association	10025673, 10570290, 15677445, 19380743, 8621719, 8662998, 8950973, 9434624, 9461587, 9541596	0.77	BioGRID, IntAct, MINT
SPRED2	coimmunoprecipitation	association	17094949	0.35	IntAct, MINT
SPRY1	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	15004239, 16893902, 19915061	0.40	BioGRID, IntAct, MINT
SPRY2	Affinity Capture-Western, Co-crystal Structure, FRET, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, isothermal titration calorimetry, x-ray crystallography	association, direct interaction, physical, physical association	11053437, 11983899, 12234920, 12593795, 12593796, 12815057, 15004239, 15962011, 16246327, 16479008, 16893902, 17255109, 17974561, 18273061, 20124286, 20461437, 20877636, 21596750	0.86	BioGRID, IntAct, MINT
SPRY4	Affinity Capture-Western, anti tag coimmunoprecipitation, isothermal titration calorimetry, x-ray crystallography	direct interaction, physical, physical association	18273061	0.61	BioGRID, IntAct, MINT
SRC	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, competition binding, isothermal titration calorimetry, protein kinase assay, pull down	direct interaction, phosphorylation reaction, physical, physical association	10829062, 11994282, 12941616, 15135048, 16636290, 17094785, 17141222, 18273061, 19861161, 22203672, 7782294	0.84	BioGRID, IntAct, MINT
STS	anti tag coimmunoprecipitation	physical association	15159412	0.40	IntAct, MINT
SYK	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, coimmunoprecipitation, experimental interaction detection, isothermal titration calorimetry, x-ray crystallography	direct interaction, phosphorylation reaction, physical, physical association	10570266, 10617633, 11042121, 11331248, 11742985, 12435267, 15536084, 15556646, 15577829, 16289966, 18273061, 7721825, 8621719, 9857068	0.74	BioGRID, IntAct, MINT
UBE2L3	Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, x-ray crystallography	direct interaction, physical	10531381, 10966114, 12234920, 15062086, 16735510	0.44	BioGRID, IntAct, MINT
VAV1	Affinity Capture-Western, Far Western, Reconstituted Complex, pull down	association, physical	11331248, 12881521, 16289966, 16356860, 18835194, 19635790, 9200440	0.35	BioGRID, IntAct, MINT
VAV2	Affinity Capture-Western, Reconstituted Complex, pull down	association, physical	11262396, 15345594, 20940296	0.35	BioGRID, IntAct, MINT
YWHAB	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, biochemical, coimmunoprecipitation	association, physical	11157475, 11697890, 19380743, 24255178, 9367879	0.64	BioGRID, IntAct, MINT
YWHAE	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, biochemical	association, physical	11697890, 25036637	0.53	BioGRID, IntAct, MINT
YWHAG	biochemical	association	11697890	0.35	IntAct, MINT
YWHAH	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, biochemical	association, physical	11697890, 25036637	0.53	BioGRID, IntAct, MINT
YWHAQ	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, biochemical, coimmunoprecipitation	association, physical	11024037, 11697890, 15094368, 19380743, 8663231, 9092538	0.76	BioGRID, IntAct, MINT
YWHAZ	Affinity Capture-Western, Two-hybrid, biochemical, tandem affinity purification	association, physical	11697890, 20618440, 9367879, 9632690	0.53	BioGRID, IntAct, MINT