Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
ABL1	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Far Western, Reconstituted Complex, experimental interaction detection	phosphorylation reaction, physical	10829062, 11494134, 12475393, 14604282, 14725908, 15556646, 16955467, 19380743, 19823681, 20675402, 8626543, 9174058, 9195915	0.31	BioGRID, IntAct, MINT
APPL1	Two-hybrid, two hybrid array, validated two hybrid	physical, physical association	25814554	0.49	BioGRID, IntAct
ARHGEF7	Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down	physical, physical association	12935897, 14505571, 16407834, 22588125, 23175185	0.59	BioGRID, IntAct, MINT
ASAP1	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	17255943	0.40	BioGRID, IntAct, MINT
BLK	Affinity Capture-Western, coimmunoprecipitation	physical, physical association	8621719	0.40	BioGRID, IntAct, MINT
CAPZA1	Affinity Capture-Luminescence, Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	25036637	0.35	BioGRID, IntAct
CBL	Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Far Western, Two-hybrid, two hybrid array	physical, physical association	10521482, 12874286, 17635922, 17679095, 22266821, 22301280, 23744067, 25784557, 25814554, 29053960	0.37	BioGRID, IntAct
CD2AP	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, imaging technique, pull down	association, direct interaction, physical, physical association	11067845, 12559036, 12618476, 12672817, 15128873, 17020880, 17072306, 17188587, 22706086, 25036637, 25872741	0.80	BioGRID, IntAct, MINT
CEP128	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
CEP170	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
CRK	Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, pull down, tandem affinity purification, two hybrid array, validated two hybrid	association, physical, physical association	10962563, 11792427, 12393469, 15581361, 16289966, 18835194, 19380743, 22974441, 25814554, 8524328, 8621483, 8626404, 8626543, 8662998, 8683103, 8943292, 9129019, 9178909, 9416834, 9461587, 9617486, 9988765	0.49, 0.88	BioGRID, IntAct, MINT
CRKL	Affinity Capture-MS, Affinity Capture-Western, Far Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection, far western blotting, pull down, two hybrid array	association, physical, physical association	10204582, 10608804, 10657627, 10907644, 11133830, 11157475, 11263968, 11399323, 11553620, 12244174, 14604282, 15107835, 15358160, 15556646, 16503409, 16982329, 18835194, 24886428, 25814554, 7545163, 8524328, 8626543, 8662998, 9092574, 9129019, 9162067, 9195915, 9311917, 9344843, 9461587, 9590251, 9820532, 9851874, 9988765	0.83	BioGRID, IntAct, MINT
CSK	Affinity Capture-MS, Affinity Capture-Western, tandem affinity purification	association, physical	11149930, 19380743	0.35	BioGRID, IntAct
EGFR	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, far western blotting, fluorescence microscopy, isothermal titration calorimetry, pull down, x-ray crystallography	association, colocalization, direct interaction, physical, physical association	10086340, 10428778, 10635327, 11239464, 11370743, 11408594, 12061819, 12593795, 12604776, 12734385, 12803489, 14505571, 14627991, 15107835, 15117950, 15159412, 15210722, 15282549, 15383614, 15465819, 15657067, 15668240, 15677445, 15735736, 15962011, 16105874, 16246327, 16729043, 16849543, 16914641, 16923119, 16969069, 17182860, 17242169, 17486068, 17545148, 17880946, 17971399, 17995934, 18271526, 18273061, 18316398, 18508924, 19155296, 19225046, 19531499, 19578043, 19713535, 19836242, 19947936, 20124286, 20308550, 20562913, 20877636, 20940296, 21772844, 22203672, 22266821, 22394513, 22591401, 22833562, 22976291, 23153581, 23158001, 23175185, 23418353, 23457600, 23774213, 23799367, 23897813, 24714105, 24797263, 25140053, 25521828, 25872741, 26055326, 26177020, 27059931, 28198003, 28791635, 7592693, 7657591, 7782294, 8662998, 9121472, 9130710, 9756944	0.96	BioGRID, IntAct, MINT
EPS8	Affinity Capture-Western, Two-hybrid, two hybrid array, validated two hybrid	physical, physical association	25814554, 27629044	0.49	BioGRID, IntAct
ERBB2	Affinity Capture-Western, Reconstituted Complex, anti tag coimmunoprecipitation	physical, physical association	12574167, 25081058, 26716506	0.40	BioGRID, IntAct
F2RL1	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, confocal microscopy	colocalization, physical association	15708858	0.56	IntAct
FBF1	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
FCGR1A	experimental interaction detection	phosphorylation reaction	9716598	0.31	IntAct, MINT
FLT1	Affinity Capture-Western, isothermal titration calorimetry	direct interaction, physical	18273061, 25387128	0.44	BioGRID, IntAct, MINT
FYN	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, competition binding, experimental interaction detection, pull down, two hybrid array	phosphorylation reaction, physical, physical association	10629042, 10829062, 12231245, 12244174, 12941616, 15190072, 15208330, 15556646, 16503409, 17094785, 25814554, 7642581, 7782294, 8621719, 8626543, 8662998, 8900205, 8995358, 9311917, 9535867	0.37, 0.80	BioGRID, IntAct, MINT
GBA	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	21098288	0.40	BioGRID, IntAct
GOLM1	anti tag coimmunoprecipitation	association	27569582	0.35	IntAct
GRAP2	Affinity Capture-Western, Co-purification, Two-hybrid, two hybrid array	physical, physical association	12496419, 25814554	0.37	BioGRID, IntAct
GRB2	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Co-purification, FRET, Far Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, competition binding, isothermal titration calorimetry, luminescence based mammalian interactome mapping, pull down, tandem affinity purification, two hybrid array, two hybrid pooling approach	association, direct interaction, physical, physical association	10025673, 10086340, 10204582, 10521482, 10570290, 10829062, 11263968, 11399323, 11792427, 11823423, 11964172, 11997436, 12839496, 12941616, 14725908, 15210722, 15677445, 16906159, 17072306, 17094785, 17944804, 17971399, 18273061, 19380743, 19836242, 20124286, 20936779, 21706016, 23799367, 25036637, 25814554, 25872741, 28514442, 7537740, 7592693, 7642581, 7791764, 8083187, 8621719, 8626404, 8649804, 8662998, 8695851, 8824292, 8900205, 8943292, 8950973, 8995358, 9092538, 9108392, 9129019, 9174058, 9178909, 9233773, 9234717, 9242692, 9259313, 9311917, 9367879, 9434624, 9461587, 9541596, 9716598, 9851874, 9872323	0.44, 0.96	BioGRID, IntAct, MINT
HCK	Affinity Capture-Western, Biochemical Activity, Far Western, Protein-peptide, Reconstituted Complex, far western blotting, pull down	physical, physical association	10092522, 11896602, 22974441, 8995358	0.52	BioGRID, IntAct
INPPL1	Affinity Capture-MS, Affinity Capture-Western, tandem affinity purification	association, physical	12504111, 15668240, 19380743, 19880507	0.35	BioGRID, IntAct
ITCH	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	12226085, 19341794	0.40	BioGRID, IntAct, MINT
ITSN1	Affinity Capture-Western, Far Western, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, far western blotting, fluorescence microscopy, pull down, two hybrid	colocalization, physical, physical association	16914641, 18539136, 18654987, 21712076	0.73	BioGRID, IntAct, MINT
KHDRBS1 	coimmunoprecipitation	physical association	9045636	0.40	IntAct
LCK	Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, pull down	direct interaction, physical, physical association	11904433, 16107303, 7721825, 8621719, 8626543, 8900205	0.75	BioGRID, IntAct, MINT
LCP2	Affinity Capture-Western, coimmunoprecipitation	physical, physical association	10204582, 10477741, 19635790, 9716598	0.40	BioGRID, IntAct, MINT
LYN	Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation	physical, physical association	12244174, 15190072, 18235045, 7721825, 7782294, 8621719, 9160881	0.40	BioGRID, IntAct, MINT
MAP1LC3B	pull down	physical association	22138575	0.40	IntAct
MAPK8	Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation	physical, physical association	11944898, 16982329	0.40	BioGRID, IntAct, MINT
MET	Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Co-localization, Far Western, Reconstituted Complex, anti bait coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection, isothermal titration calorimetry, mass spectrometry studies of complexes, proximity ligation assay, surface plasmon resonance, x-ray crystallography	direct interaction, physical, physical association, ubiquitination reaction	11894096, 15123609, 16397241, 18273061, 19433454, 19450681, 21163258, 21222362, 25241761	0.86	BioGRID, IntAct, MINT
MST1R	Affinity Capture-Western, isothermal titration calorimetry	direct interaction, physical	12802274, 16740632, 18273061	0.44	BioGRID, IntAct, MINT
MZF1	Two-hybrid, two hybrid array	physical, physical association	25814554	0.37	BioGRID, IntAct
NCK1	Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, phage display, pull down	direct interaction, physical, physical association	10204582, 10372803, 10829062, 10967110, 11494134, 16503409, 24287595, 7517397, 9851874	0.61	BioGRID, IntAct, MINT
NPHP1	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
NTRK1	Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	21570973, 25921289	0.40	BioGRID, IntAct, MINT
PDGFRB	coimmunoprecipitation	association	17620338	0.35	IntAct, MINT
PIK3CA	Affinity Capture-MS, Affinity Capture-Western, tandem affinity purification	association, physical	11157475, 19380743, 9119889	0.35	BioGRID, IntAct
PIK3CB	Affinity Capture-MS, Affinity Capture-Western, tandem affinity purification	association, physical	14530346, 19380743	0.35	BioGRID, IntAct
PIK3R1	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Far Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection, far western blotting, pull down, tandem affinity purification, two hybrid, two hybrid array, validated two hybrid	association, physical, physical association	10025673, 10358153, 10620516, 10918571, 11030146, 11042121, 11087752, 11157475, 11418612, 11944898, 11994282, 14530346, 15107835, 15556646, 15581361, 16135792, 16219545, 16289966, 16982329, 17237826, 18374639, 19190244, 19380743, 19861161, 21203488, 24113870, 25814554, 7642581, 7791764, 8612729, 8621719, 8662998, 8695807, 8702998, 8896416, 8941725, 8995243, 9092538, 9160881, 9174058, 9259313, 9414268, 9461587, 9541596, 9890943, 9890970, 9918857, 9988765	0.49, 0.94	BioGRID, IntAct, MINT
PIK3R2	Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, tandem affinity purification, two hybrid array, validated two hybrid	association, physical, physical association	11133830, 15107835, 19190244, 19380743, 25814554, 7629144	0.62	BioGRID, IntAct
PIK3R3	Affinity Capture-Luminescence, Two-hybrid, luminescence based mammalian interactome mapping, two hybrid array, validated two hybrid	physical, physical association	25814554	0.57	BioGRID, IntAct
PLCG1	Affinity Capture-MS, Affinity Capture-Western, Co-localization, FRET, Far Western, Reconstituted Complex, proximity ligation assay	physical, physical association	12061819, 12803489, 12941616, 16467851, 16503409, 17372230, 25241761, 9712732	0.40	BioGRID, IntAct
PRKCA	Affinity Capture-Western, Biochemical Activity, Two-hybrid, two hybrid array	physical, physical association	10358153, 25814554	0.37	BioGRID, IntAct
PRPSAP2	Affinity Capture-Luminescence, Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	25036637	0.35	BioGRID, IntAct
PSMC1	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
PTPN22	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	10068674	0.40	BioGRID, IntAct, MINT
PTPRB	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRC 	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRG	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRJ	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRK	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRO	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
RET	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down	physical, physical association	12727845, 15677445	0.70	BioGRID, IntAct, MINT
SERPINA5	Two-hybrid, two hybrid array	physical, physical association	25814554	0.37	BioGRID, IntAct
SFN	Affinity Capture-Western, biochemical	association, physical	11697890	0.35	BioGRID, IntAct, MINT
SGTA	luminescence based mammalian interactome mapping	physical association	25036637	0.40	IntAct
SH2B2	Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, anti tag coimmunoprecipitation, isothermal titration calorimetry, pull down	association, direct interaction, physical, physical association	10374881, 15737992, 17620296, 18273061, 9989826	0.66	BioGRID, IntAct, MINT
SH3GL2	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical, physical association	11894095	0.50	BioGRID, IntAct, MINT
SH3KBP1	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Co-fractionation, Reconstituted Complex, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, isothermal titration calorimetry, nuclear magnetic resonance, pull down, two hybrid	association, direct interaction, physical, physical association	10679202, 11071869, 11152963, 11894095, 11894096, 12135478, 12177062, 12618476, 12874286, 14596919, 15090612, 15107835, 15456872, 15962011, 16228008, 16407834, 17072306, 17306257, 17675467, 19268472, 19417776, 19531213, 20130058, 20711168, 21830225, 22262777, 22833562, 24167568, 25036637, 25472714, 28514442	0.97	BioGRID, IntAct, MINT
SHC1	Affinity Capture-MS, Affinity Capture-Western, coimmunoprecipitation, pull down, tandem affinity purification	association, physical, physical association	10025673, 10570290, 15677445, 19380743, 8621719, 8662998, 8950973, 9434624, 9461587, 9541596	0.77	BioGRID, IntAct, MINT
SPRED2	coimmunoprecipitation	association	17094949	0.35	IntAct, MINT
SPRY1	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	15004239, 16893902, 19915061	0.40	BioGRID, IntAct, MINT
SPRY2	Affinity Capture-Western, Co-crystal Structure, FRET, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, isothermal titration calorimetry, x-ray crystallography	association, direct interaction, physical, physical association	11053437, 11983899, 12234920, 12593795, 12593796, 12815057, 15004239, 15962011, 16246327, 16479008, 16893902, 17255109, 17974561, 18273061, 20124286, 20461437, 20877636, 21596750	0.86	BioGRID, IntAct, MINT
SPRY4	Affinity Capture-Western, anti tag coimmunoprecipitation, isothermal titration calorimetry, x-ray crystallography	direct interaction, physical, physical association	18273061	0.61	BioGRID, IntAct, MINT
SPTA1	Affinity Capture-MS, tandem affinity purification	association, physical	19380743	0.35	BioGRID, IntAct
SRC	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, competition binding, isothermal titration calorimetry, protein kinase assay, pull down	direct interaction, phosphorylation reaction, physical, physical association	10829062, 11994282, 12941616, 15135048, 16636290, 17094785, 17141222, 18273061, 19861161, 22203672, 7782294	0.84	BioGRID, IntAct, MINT
STAT3 	two hybrid array, validated two hybrid	physical association	25814554	0.49	IntAct
STAT5A	Affinity Capture-Western, Two-hybrid, two hybrid array, validated two hybrid	physical, physical association	23533197, 25814554	0.49	BioGRID, IntAct
STS	anti tag coimmunoprecipitation	physical association	15159412	0.40	IntAct, MINT
SYK	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, coimmunoprecipitation, experimental interaction detection, isothermal titration calorimetry, x-ray crystallography	direct interaction, phosphorylation reaction, physical, physical association	10570266, 10617633, 11042121, 11331248, 11742985, 12435267, 15536084, 15556646, 15577829, 16289966, 18273061, 7721825, 8621719, 9857068	0.74	BioGRID, IntAct, MINT
TRAF4	Two-hybrid, two hybrid array	physical, physical association	22493164	0.37	BioGRID, IntAct
TRIM21	Affinity Capture-MS, tandem affinity purification	association, physical	19380743	0.35	BioGRID, IntAct
TRIM8	Two-hybrid, two hybrid array	physical, physical association	22493164	0.37	BioGRID, IntAct
UBE2D2	Co-crystal Structure, Reconstituted Complex, surface plasmon resonance, x-ray crystallography	direct interaction, physical, physical association	10514377, 15117950, 18632619, 20675402, 22266821, 22301280, 24113870, 27609087, 28791635	0.61	BioGRID, IntAct
UBE2L3	Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, x-ray crystallography	direct interaction, physical	10531381, 10966114, 12234920, 15062086, 16735510	0.44	BioGRID, IntAct, MINT
VAV1	Affinity Capture-Western, Far Western, Reconstituted Complex, pull down	association, physical	11331248, 12881521, 16289966, 16356860, 18835194, 19635790, 9200440	0.35	BioGRID, IntAct, MINT
VAV2	Affinity Capture-Western, Reconstituted Complex, pull down	association, physical	11262396, 15345594, 20940296	0.35	BioGRID, IntAct, MINT
VCAM1	cross-linking study	association	22623428	0.35	IntAct
XRCC5	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
YWHAB	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, biochemical, coimmunoprecipitation	association, physical	11157475, 11697890, 19380743, 24255178, 9367879	0.64	BioGRID, IntAct, MINT
YWHAE	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, biochemical	association, physical	11697890, 25036637	0.53	BioGRID, IntAct, MINT
YWHAG	biochemical	association	11697890	0.35	IntAct, MINT
YWHAH	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, biochemical	association, physical	11697890, 25036637	0.53	BioGRID, IntAct, MINT
YWHAQ	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, biochemical, coimmunoprecipitation	association, physical	11024037, 11697890, 15094368, 19380743, 8663231, 9092538	0.76	BioGRID, IntAct, MINT
YWHAZ	Affinity Capture-Western, Two-hybrid, biochemical, tandem affinity purification	association, physical	11697890, 20618440, 9367879, 9632690	0.53	BioGRID, IntAct, MINT
ZAP70	Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, surface plasmon resonance, x-ray crystallography	direct interaction, physical, physical association	10078535, 10779765, 11353765, 16503409, 22266821, 29053960, 8798643, 9407100, 9988730	0.61	BioGRID, IntAct