Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ATG12 Affinity Capture-Western physical 22152474 NA BioGRID ATP2A3 Affinity Capture-Luminescence physical 9788433 NA BioGRID AVEN Affinity Capture-Western, Two-hybrid physical 10949025 NA BioGRID BAD Affinity Capture-Western, Far Western, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, enzyme linked immunosorbent assay, surface plasmon resonance, two hybrid direct interaction, physical, physical association 10611223, 15694340, 15849194, 15990872, 16697956, 17446862, 20603619, 7834748, 9305851, 9388232, 9463381 0.81 BioGRID, IntAct, MINT BAG1 Reconstituted Complex physical 9305631 NA BioGRID BAG3 Affinity Capture-Western physical 23341456 NA BioGRID BAK1 Affinity Capture-Western, Protein-peptide, anti bait coimmunoprecipitation, fluorescence polarization spectroscopy direct interaction, physical, physical association 11728179, 14980220, 20836993, 26004684, 9463381 0.61 BioGRID, IntAct BARD1 Co-localization physical 26022179 NA BioGRID BAX Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, enzyme linked immunosorbent assay, fluorescence microscopy, fluorescence technology association, colocalization, physical, physical association 10620799, 10716992, 14980220, 15231068, 16642033, 17097560, 17289999, 17525735, 18981409, 21199865, 21458670, 21671007, 21778226, 22262057, 23479509, 26004684, 8358790, 9111042, 9388232, 9463381 0.94 BioGRID, IntAct, MINT BBC3 Affinity Capture-Western, Protein-peptide, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy, surface plasmon resonance direct interaction, physical, physical association 11463392, 15694340, 16697956, 17289999 0.40, 0.76 BioGRID, IntAct BCAP31 Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, far western blotting physical, physical association 9334338 0.52 BioGRID, IntAct BCL2 Affinity Capture-Western, Reconstituted Complex, anti tag coimmunoprecipitation physical, physical association 18835031, 9111042, 9463381 0.59 BioGRID, IntAct BCL2L1 Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, fluorescence polarization spectroscopy direct interaction, physical 12137781, 14980220, 18835031, 26186194, 28514442 0.44 BioGRID, IntAct BCL2L10 Affinity Capture-Western physical 11278245 NA BioGRID BCL2L11 Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, fluorescence polarization spectroscopy, surface plasmon resonance association, direct interaction, physical, physical association 15694340, 16697956, 17074758, 17097560, 17289999, 17692808, 19805519, 20836993, 21199865, 21671007, 23845444, 26004684, 26186194, 28514442, 9430630, 9731710 0.35, 0.70, 0.71, 0.92 BioGRID, IntAct, MINT BCLAF1 anti bait coimmunoprecipitation association, physical association 23541952 0.50 IntAct BECN1 Affinity Capture-Western, Co-purification, FRET, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, cosedimentation through density gradient, pull down, two hybrid association, colocalization, physical, physical association 16179260, 17446862, 18641390, 19050071, 19180116, 19347031, 19959994, 20010695, 20622903, 20711182, 20889974, 21139567, 21358617, 21543763, 21971985, 22622204, 23168911, 23316280, 23479509, 23504944, 23541952, 23564079, 23954414, 24034250, 24472739, 24599950, 25891078, 25984893, 28128446, 29079782, 9765397 0.95 BioGRID, IntAct, MINT BECN2 anti tag coimmunoprecipitation physical association 23954414 0.40 IntAct BFAR Affinity Capture-Western, Two-hybrid physical 10716992 NA BioGRID BID Affinity Capture-Western, Co-fractionation, Protein-peptide, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, fluorescence polarization spectroscopy, surface plasmon resonance association, direct interaction, physical, physical association 12624108, 15520201, 15694340, 16697956, 17289999, 18835031, 19074266, 9463381 0.87 BioGRID, IntAct BIK Affinity Capture-Western, Protein-peptide, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy, two hybrid array, two hybrid prey pooling approach direct interaction, physical, physical association 12853473, 15694340, 16697956, 17289999, 9463381, 9488477, 0.80 BioGRID, IntAct BLID Affinity Capture-Western physical 20400521 NA BioGRID BLK Reconstituted Complex physical 9525867 NA BioGRID BMF Affinity Capture-Western, Protein-peptide, anti tag coimmunoprecipitation physical, physical association 11546872, 16697956, 17289999 0.40 BioGRID, IntAct BNIP1 Reconstituted Complex physical 10217402 NA BioGRID BNIP2 Reconstituted Complex, Two-hybrid, two hybrid physical, physical association 10381623, 12901880, 7954800 0.37 BioGRID, IntAct, MINT BNIP3 Affinity Capture-Western, Two-hybrid, two hybrid physical, physical association 10381623, 10625696, 23504944, 7954800 0.37 BioGRID, IntAct, MINT BNIP3L Affinity Capture-Western, Reconstituted Complex, pull down direct interaction, physical 10467396, 9973195 0.44 BioGRID, IntAct BNIPL Affinity Capture-Western, Two-hybrid physical 12901880 NA BioGRID BRCA1 Affinity Capture-Western, FRET, confocal microscopy, proximity ligation assay colocalization, physical, physical association 21444675 0.46 BioGRID, IntAct CALR cosedimentation through density gradient colocalization 21139567 0.35 IntAct, MINT CAPN2 Biochemical Activity, Reconstituted Complex physical 12000759 NA BioGRID CASP2 Phenotypic Suppression genetic 11832478 NA BioGRID CASP3 Biochemical Activity physical 11752215 NA BioGRID CASP8 Affinity Capture-Western, Phenotypic Suppression, Two-hybrid, two hybrid genetic, physical, physical association 11406564, 11832478, 16183855 0.37 BioGRID, IntAct CDK1 Affinity Capture-Western, Biochemical Activity physical 11326318, 11774038, 9668078 NA BioGRID CDK4 Negative Genetic genetic 28319113 NA BioGRID CHUK Affinity Capture-Western physical 22262057 NA BioGRID CISD2 Affinity Capture-Western physical 20010695 NA BioGRID CRYAB Affinity Capture-Western physical 20841355 NA BioGRID DYNLL1 Affinity Capture-Western physical 10198631 NA BioGRID FKBP8 Affinity Capture-Western, Far Western, Reconstituted Complex, Two-hybrid, pull down, two hybrid physical, physical association 12510191, 15733859, 15990872, 17379601, 17942410 0.51 BioGRID, IntAct, MINT GIMAP5 Affinity Capture-Western physical 16509771 NA BioGRID HIF1A Affinity Capture-Western physical 20668552 NA BioGRID HNRNPD Two-hybrid physical 14769789 NA BioGRID HRK Affinity Capture-Western, Protein-peptide, Two-hybrid physical 15694340, 9130713 NA BioGRID HSP90AA1 Affinity Capture-Western physical 20668552, 21543763 NA BioGRID HSPA1A Affinity Capture-Western physical 10354271 NA BioGRID HSPA9 cosedimentation through density gradient colocalization 21139567 0.35 IntAct, MINT IKBKB Affinity Capture-Western physical 22262057 NA BioGRID IKBKG Affinity Capture-Western physical 17363905 NA BioGRID IRS1 Affinity Capture-Western physical 10679027 NA BioGRID IRS2 Affinity Capture-Western physical 10679027 NA BioGRID ITLN1 Dosage Rescue genetic 22647378 NA BioGRID ITM2B Affinity Capture-Western physical 12082633 NA BioGRID ITPR1 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation physical, physical association 15613488, 19706527 0.40 BioGRID, IntAct KEAP1 Affinity Capture-Western physical 24127568 NA BioGRID KRAS Affinity Capture-Western physical 19433448 NA BioGRID LRRK2 protein kinase assay phosphorylation reaction 25446991 0.44 IntAct MAPK1 Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation, experimental interaction detection phosphorylation reaction, physical, physical association 15225643 0.49 BioGRID, IntAct, MINT MAPK8 Biochemical Activity, experimental interaction detection phosphorylation reaction, physical 15733859 0.31 BioGRID, IntAct, MINT MAT2A Affinity Capture-Western physical 26416353 NA BioGRID MCL1 cosedimentation through density gradient colocalization 21139567 0.35 IntAct, MINT MDM4 Affinity Capture-Western, anti bait coimmunoprecipitation association, physical, physical association 19521340, 24445145 0.50 BioGRID, IntAct, MINT MEX3D Two-hybrid physical 14769789 NA BioGRID MOAP1 Affinity Capture-Western physical 11060313 NA BioGRID MYC Affinity Capture-Western, Co-localization physical 15210690 NA BioGRID NAF1 anti bait coimmunoprecipitation, pull down direct interaction, physical association 20010695 0.54 IntAct, MINT NLRP1 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, confocal microscopy, pull down association, colocalization, direct interaction, physical association 17418785, 19223583 0.75 IntAct NMT2 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 16530191 0.40 BioGRID, IntAct, MINT NR4A1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, circular dichroism, fluorescence polarization spectroscopy association, direct interaction, physical, physical association 14980220, 16434970, 18835031 0.67 BioGRID, IntAct PARP1 Reconstituted Complex physical 11790116 NA BioGRID PIN1 Affinity Capture-Western physical 11326318 NA BioGRID PMAIP1 Affinity Capture-Western, Protein-peptide, anti bait coimmunoprecipitation, pull down, surface plasmon resonance direct interaction, physical, physical association 10807576, 15694340, 21454712 0.52, 0.54 BioGRID, IntAct PML Affinity Capture-Western physical 15231068 NA BioGRID PPARA Affinity Capture-Western, Biochemical Activity physical 26556865 NA BioGRID PPID Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 19228691 NA BioGRID PPIF two hybrid physical association 19228691 0.37 IntAct PPP1CA Affinity Capture-Western, antibody array physical, physical association 17274640 0.40 BioGRID, IntAct PPP1CB Affinity Capture-Western, antibody array physical, physical association 17274640 0.40 BioGRID, IntAct PPP1CC Affinity Capture-Western, antibody array physical, physical association 17274640 0.40 BioGRID, IntAct PPP2CA Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti bait coimmunoprecipitation, experimental interaction detection dephosphorylation reaction, physical, physical association 15225643, 9852076 0.49 BioGRID, IntAct, MINT PPP2R5A Affinity Capture-Western physical 11929874 NA BioGRID PPP3CA Affinity Capture-Western physical 19706527, 9109491 NA BioGRID PPP3CC Reconstituted Complex physical 15757646 NA BioGRID PPP3R1 fluorescence microscopy, pull down colocalization, direct interaction 15757646 0.49 IntAct, MINT PRKN Affinity Capture-Western, Reconstituted Complex physical 20889974 NA BioGRID PSEN1 Affinity Capture-Western, Two-hybrid physical 10521466 NA BioGRID RAD9A Affinity Capture-Western, Two-hybrid physical 10620799, 18794804 NA BioGRID RAF1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 12488548, 15849194, 8929532 NA BioGRID RRAS Affinity Capture-Western, Two-hybrid physical 8232588 NA BioGRID RTL10 anti tag coimmunoprecipitation association 23055042 0.35 IntAct RTN3 Affinity Capture-Western physical 17191123 NA BioGRID RTN4 Affinity Capture-Western, Two-hybrid physical 11126360, 17191123 NA BioGRID SEPT4 Affinity Capture-Western, PCA, Protein-peptide physical 29020630 NA BioGRID SERPINB8 Affinity Capture-Western physical 15231068 NA BioGRID SIVA1 pull down physical association 14739602 0.40 IntAct SMN1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 9389483 NA BioGRID SOD1 Affinity Capture-Western, Reconstituted Complex physical 15233914 NA BioGRID SPNS1 Affinity Capture-Western, anti tag coimmunoprecipitation, confocal microscopy colocalization, physical, physical association 12815463 0.46 BioGRID, IntAct SQSTM1 Affinity Capture-Western, Reconstituted Complex physical 23564079, 25311206 NA BioGRID TMBIM6 Affinity Capture-Western physical 9660918 NA BioGRID TOMM20 Reconstituted Complex physical 9119086 NA BioGRID TP53 Affinity Capture-Western, anti bait coimmunoprecipitation association, physical, physical association 12667443, 19521340, 21597459, 21624955 0.56 BioGRID, IntAct, MINT TP53AIP1 Affinity Capture-Western physical 12019168 NA BioGRID TP53BP2 Protein-peptide, Reconstituted Complex, Two-hybrid, fluorescence technology, peptide array, proximity ligation assay, surface plasmon resonance direct interaction, physical 18719108, 8668206 0.65 BioGRID, IntAct UBE2I Affinity Capture-Western physical 26416353 NA BioGRID VDAC1 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 19706527 0.40 BioGRID, IntAct VRK2 two hybrid physical association 16963744 0.37 IntAct XIAP Biochemical Activity, Reconstituted Complex physical 29020630 NA BioGRID