Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PXN	9718	COSM5048900,	oesophagus	carcinoma	p.P159L	Substitution - Missense	12:120222880-120222880,	PATHOGENIC	0.96474	24686850
PXN	9718	COSM96167,	breast	carcinoma	p.L457L	Substitution - coding silent	12:120213878-120213878,	PATHOGENIC	0.82668	20668451