Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PTPN21	9651	COSM314581,	lung	carcinoma	p.A994V	Substitution - Missense	14:88469941-88469941,	PATHOGENIC	0.99116	22941188
PTPN21	9651	COSM142821,	skin	malignant_melanoma	p.E277K	Substitution - Missense	14:88497226-88497226,	PATHOGENIC	0.97858	19074898
PTPN21	9651	COSM142822,	skin	malignant_melanoma	p.Y586H	Substitution - Missense	14:88479675-88479675,	PATHOGENIC	0.90879	19074898
PTPN21	9651	COSM142823,	skin	malignant_melanoma	p.D742N	Substitution - Missense	14:88479207-88479207,	NEUTRAL	0.16976	19074898