Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
ARAF	Affinity Capture-MS, Biochemical Activity, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification	association, physical	17979178, 24114843, 24746704, 26496610	0.69	BioGRID, IntAct
AURKA	two hybrid array	physical association	24412244	0.37	IntAct, MINT
BANP	Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid	physical, physical association	25416956, 	0.49, 0.56	BioGRID, IntAct
BAX	two hybrid array	physical association	24412244	0.37	IntAct, MINT
BIRC6	anti bait coimmunoprecipitation	physical association	18329369	0.40	IntAct
BLVRA	anti bait coimmunoprecipitation	association	18463290	0.35	IntAct
BMPR1A	two hybrid array	physical association	24412244	0.37	IntAct, MINT
BRAF	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Synthetic Lethality, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence technology, kinase homogeneous time resolved fluorescence, molecular sieving, protein kinase assay, pull down, surface plasmon resonance, tandem affinity purification	association, direct interaction, genetic, phosphorylation reaction, physical, physical association	16810323, 16888650, 17979178, 18332145, 19371126, 20212043, 23934108, 24746704, 25155755, 25437913, 25600339, 26496610, 26627737, 27034005, 28514442	0.98	BioGRID, IntAct
BTRC	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence microscopy	colocalization, physical, physical association	24211253	0.56	BioGRID, IntAct, MINT
BUB1	two hybrid array	physical association	24412244	0.37	IntAct, MINT
CALR	confocal microscopy	colocalization	22752157	0.27	IntAct
CDH1	two hybrid array	physical association	24412244	0.37	IntAct, MINT
CDKN2A 	two hybrid array	physical association	24412244	0.37	IntAct, MINT
CEP170P1	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
CFLAR	anti tag coimmunoprecipitation	physical association	17110930	0.40	IntAct, MINT
CTNNA1	two hybrid array	physical association	24412244	0.37	IntAct, MINT
DCP1A	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
ERBB2	two hybrid array	physical association	24412244	0.37	IntAct, MINT
FBXW7 	two hybrid array	physical association	24412244	0.37	IntAct, MINT
HLA-B	anti bait coimmunoprecipitation	physical association	17353931	0.40	IntAct
HSCB	anti bait coimmunoprecipitation	association	28380382	0.35	IntAct
HSPA8	Affinity Capture-MS, tandem affinity purification	association, physical	17979178	0.35	BioGRID, IntAct
KSR1	Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, tandem affinity purification	association, physical	15090600, 17979178, 18332145, 26496610, 27086506	0.64	BioGRID, IntAct
KSR2	Affinity Capture-Western, anti tag coimmunoprecipitation	association, physical	12975377, 27086506	0.35	BioGRID, IntAct
MAP3K1	Affinity Capture-Western, anti tag coimmunoprecipitation	physical, physical association	10969079, 14500727, 17110930	0.40	BioGRID, IntAct, MINT
MAP3K8	Biochemical Activity, pull down	physical, physical association	12832462, 16291755, 8631303	0.40	BioGRID, IntAct
MAPK1	Affinity Capture-Western, Biochemical Activity, PCA, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, protein kinase assay	phosphorylation reaction, physical, physical association	10757792, 11266467, 11279118, 11352917, 11823456, 12697810, 12788955, 17255949, 19058874, 21336309, 21675959, 23241949, 24623782	0.61	BioGRID, IntAct, MINT
MAPK3	Affinity Capture-Western, Biochemical Activity, Co-localization, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation	association, physical, physical association	10748187, 19058874, 19197339, 8226933, 8626767, 9006895, 9733512	0.50	BioGRID, IntAct, MINT
MLH3	two hybrid array	physical association	24412244	0.37	IntAct, MINT
MSH6 	two hybrid array	physical association	24412244	0.37	IntAct, MINT
MYC	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
ODC1	two hybrid array	physical association	24412244	0.37	IntAct, MINT
PDGFRL	two hybrid array	physical association	24412244	0.37	IntAct, MINT
PEBP4	Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation	association, physical	15302887, 19197339	0.46	BioGRID, IntAct, MINT
PIK3CA	two hybrid array	physical association	24412244	0.37	IntAct, MINT
PIN1	anti tag coimmunoprecipitation, two hybrid	physical association	20179161	0.51	IntAct
PKM	protein kinase assay	phosphorylation reaction	24606918	0.44	IntAct
POC5	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
PSMD10	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation	association, physical	24338975	0.46	BioGRID, IntAct
PTPRJ	two hybrid array	physical association	24412244	0.37	IntAct, MINT
RAF1	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, surface plasmon resonance, tandem affinity purification	association, direct interaction, physical, physical association	10757792, 10958680, 15485920, 15866172, 16093354, 17724343, 17979178, 18556463, 19058874, 19197339, 20212043, 21336309, 23934108, 24746704, 25155755, 26496610, 27703006, 9311917	0.44, 0.95	BioGRID, IntAct, MINT
RBM33	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
SKA3	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
SMAD2	two hybrid array	physical association	24412244	0.37	IntAct, MINT
SRC	two hybrid array	physical association	24412244	0.37	IntAct, MINT
STK11	Synthetic Lethality, two hybrid array	genetic, physical association	24412244, 27453043	0.37	BioGRID, IntAct, MINT
TCTN1	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
TGFBR2	two hybrid array	physical association	24412244	0.37	IntAct, MINT
THOC2	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct
TLR2	two hybrid array	physical association	24412244	0.37	IntAct, MINT
TRIB1 	anti tag coimmunoprecipitation	physical association	15299019	0.40	IntAct
TRIB3	anti tag coimmunoprecipitation	physical association	15299019	0.40	IntAct
VRK2	coimmunoprecipitation, pull down	association, physical association	20679487, 22752157	0.40, 0.50, 0.52	IntAct
WNK1 	two hybrid pooling approach	physical association	20936779	0.37	IntAct
YAP1	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence microscopy	colocalization, physical, physical association	24211253	0.56	BioGRID, IntAct, MINT
YWHAB	Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation, tandem affinity purification	association, physical	10409742, 17979178, 24255178	0.53	BioGRID, IntAct
YWHAE	Affinity Capture-MS, tandem affinity purification	association, physical	17979178	0.35	BioGRID, IntAct
YWHAZ	Affinity Capture-MS, tandem affinity purification	association, physical	17979178	0.35	BioGRID, IntAct
ZNF277	Affinity Capture-MS, anti tag coimmunoprecipitation	association, physical	26496610	0.35	BioGRID, IntAct