Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
CYTH2 	anti bait coimmunoprecipitation	association	17167487	0.35	IntAct
CYTH3 	anti bait coimmunoprecipitation	association	17167487	0.35	IntAct
DDR1	protein kinase assay	phosphorylation reaction	17721511	0.44	IntAct
EBI-1108795	anti bait coimmunoprecipitation	physical association	14968112	0.40	IntAct
EGFR	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
EGLN3	anti tag coimmunoprecipitation	association	26972000	0.35	IntAct
EIF4E	anti bait coimmunoprecipitation	association	23770097	0.35	IntAct, MINT
ERBB2	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
GRB2	Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, anti tag coimmunoprecipitation	association, physical	12173038, 21706016, 22974441, 8491186, 8536716	0.35	BioGRID, IntAct
IGF1R	Affinity Capture-Western, Two-hybrid, two hybrid	physical, physical association	10082579, 7541045, 7559507, 8776723	0.37	BioGRID, IntAct
INSR	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, two hybrid	association, direct interaction, physical, physical association	11606564, 11781100, 16582879, 17167487, 25667086, 7499194, 7935368, 8626379, 8662806	0.35, 0.70	BioGRID, IntAct, MINT
LRRK2	protein array	direct interaction	24947832	0.44	IntAct
NUMB 	two hybrid array, validated two hybrid	physical association	25814554	0.49	IntAct
PABPC1	anti bait coimmunoprecipitation	association, physical association	23770097	0.50	IntAct, MINT
PELI1	Two-hybrid, two hybrid array	physical, physical association	25814554	0.37	BioGRID, IntAct
PIK3CA	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down	association, direct interaction, physical, physical association	12933652, 14511371, 16150444, 16354680, 23604317, 23643389	0.75	BioGRID, IntAct, MINT
PIK3R1	Affinity Capture-Luminescence, Affinity Capture-Western, Far Western, Protein-peptide, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, cross-linking study, enzymatic study, luminescence based mammalian interactome mapping, nuclear magnetic resonance, pull down, surface plasmon resonance, two hybrid, two hybrid array, validated two hybrid	association, physical, physical association	11403293, 11416002, 12107746, 12173038, 12730242, 1381348, 14511371, 14632132, 15514089, 16150444, 16230374, 16354680, 17640984, 19561084, 22974441, 23439647, 23643389, 25814554, 7680095, 7680644, 8175658, 8382612, 8628286, 9564850	0.57, 0.92	BioGRID, IntAct, MINT
PIK3R3	Affinity Capture-Luminescence, Affinity Capture-Western, Two-hybrid, luminescence based mammalian interactome mapping, two hybrid array, validated two hybrid	physical, physical association	10417350, 25814554, 9415396	0.57	BioGRID, IntAct
PTPN1	Affinity Capture-Western, Reconstituted Complex, phosphatase assay	dephosphorylation reaction, physical	10660596, 11579209	0.44	BioGRID, IntAct, MINT
PTPN11	Affinity Capture-Western, Biochemical Activity, Protein-peptide, Reconstituted Complex, surface plasmon resonance	association, physical	11781100, 22974441, 7513703, 8505282, 9756938	0.35	BioGRID, IntAct, MINT
PTPRD	protein array	direct interaction	22305495	0.44	IntAct, MINT
SFN	Affinity Capture-MS, tandem affinity purification	physical, physical association	15778465	0.40	BioGRID, IntAct, MINT
SIRT1	Affinity Capture-Western, anti bait coimmunoprecipitation	physical, physical association	17901049, 21241768	0.40	BioGRID, IntAct
SMAD3	Affinity Capture-MS, tandem affinity purification	physical, physical association	18729074	0.40	BioGRID, IntAct
YWHAE	Reconstituted Complex, Two-hybrid, competition binding, pull down, two hybrid	association, direct interaction, physical, physical association	9111084, 9312143	0.68	BioGRID, IntAct, MINT