| GeneID | Gene_Symbol | DisGeNet_diseaseID | Disease_name |  DisGeNet score | DisGeNet_sourceDB |
| 3667 | IRS1 | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 0.669945219479228 | BEFREE;CTD_human;GAD;MGD;RGD;UNIPROT |
| 3667 | IRS1 | C0028754 | Obesity | 0.299518278324824 | BEFREE;CTD_human;GAD;RGD |
| 3667 | IRS1 | C0011853 | Diabetes Mellitus, Experimental | 0.28 | CTD_human;RGD |
| 3667 | IRS1 | C0021655 | Insulin Resistance | 0.221663256709592 | CTD_human;GAD |
| 3667 | IRS1 | C0011849 | Diabetes Mellitus | 0.210099378481255 | BEFREE;CTD_human;GAD |
| 3667 | IRS1 | C1956346 | Coronary Artery Disease | 0.207286598104494 | BEFREE;CTD_human;GAD |
| 3667 | IRS1 | C0033578 | Prostatic Neoplasms | 0.205465824929628 | CTD_human;LHGDN |
| 3667 | IRS1 | C2239176 | Liver carcinoma | 0.20357144819477 | BEFREE;CTD_human |
| 3667 | IRS1 | C0020459 | Hyperinsulinism | 0.201923087489492 | BEFREE;CTD_human |
| 3667 | IRS1 | C0007621 | Neoplastic Cell Transformation | 0.2 | CTD_human |
| 3667 | IRS1 | C0020473 | Hyperlipidemia | 0.2 | CTD_human |
| 3667 | IRS1 | C0032927 | Precancerous Conditions | 0.2 | CTD_human |
| 3667 | IRS1 | C0524620 | Metabolic Syndrome X | 0.087561324888707 | BEFREE;GAD;RGD |
| 3667 | IRS1 | C0002395 | Alzheimer's Disease | 0.0867371445360677 | BEFREE;GAD;RGD |
| 3667 | IRS1 | C0022661 | Kidney Failure, Chronic | 0.082407028523288 | GAD;RGD |
| 3667 | IRS1 | C0400966 | Non-alcoholic Fatty Liver Disease | 0.0808241803526393 | BEFREE;RGD |
| 3667 | IRS1 | C0015934 | Fetal Growth Retardation | 0.08 | RGD |
| 3667 | IRS1 | C0029456 | Osteoporosis | 0.08 | RGD |
| 3667 | IRS1 | C0243026 | Sepsis | 0.08 | RGD |
| 3667 | IRS1 | C0032460 | Polycystic Ovary Syndrome | 0.0439368939019075 | BEFREE;GAD;LHGDN |
| 3667 | IRS1 | C0006142 | Malignant neoplasm of breast | 0.0181446444037581 | BEFREE;GAD |
| 3667 | IRS1 | C1458155 | Mammary Neoplasms | 0.0155364926562478 | BEFREE;GAD;LHGDN |
| 3667 | IRS1 | C1527249 | Colorectal Cancer | 0.0145076836743579 | BEFREE;GAD |
| 3667 | IRS1 | C0007222 | Cardiovascular Diseases | 0.0086970338055548 | BEFREE;GAD;LHGDN |
| 3667 | IRS1 | C0376358 | Malignant neoplasm of prostate | 0.0083199927067164 | BEFREE;GAD |
| 3667 | IRS1 | C0678222 | Breast Carcinoma | 0.008241803526393 | BEFREE |
| 3667 | IRS1 | C0206081 | Hyperandrogenism | 0.00809642307981595 | BEFREE;GAD;LHGDN |
| 3667 | IRS1 | C0011854 | Diabetes Mellitus, Insulin-Dependent | 0.0080452659225033 | BEFREE;GAD |
| 3667 | IRS1 | C0020538 | Hypertensive disease | 0.0077705391382902 | BEFREE;GAD |
| 3667 | IRS1 | C0009375 | Colonic Neoplasms | 0.00754696951138975 | GAD;LHGDN |
| 3667 | IRS1 | C0010054 | Coronary Arteriosclerosis | 0.0061876909676415 | BEFREE;GAD |
| 3667 | IRS1 | C0010068 | Coronary heart disease | 0.0061876909676415 | BEFREE;GAD |
| 3667 | IRS1 | C0020507 | Hyperplasia | 0.0054658249296275 | LHGDN |
| 3667 | IRS1 | C0011847 | Diabetes | 0.0052198089000489 | BEFREE |
| 3667 | IRS1 | C0030297 | Pancreatic Neoplasm | 0.00513994098810175 | GAD;LHGDN |
| 3667 | IRS1 | C0520679 | Sleep Apnea, Obstructive | 0.00513994098810175 | GAD;LHGDN |
| 3667 | IRS1 | C0032914 | Pre-Eclampsia | 0.004814057046576 | GAD |
| 3667 | IRS1 | C0034013 | Precocious Puberty | 0.004814057046576 | GAD |
| 3667 | IRS1 | C0518010 | body mass | 0.004814057046576 | GAD |
| 3667 | IRS1 | C1272641 | Systemic arterial pressure | 0.004814057046576 | GAD |
| 3667 | IRS1 | C0007102 | Malignant tumor of colon | 0.0037806624443535 | BEFREE;GAD |
| 3667 | IRS1 | C0019196 | Hepatitis C | 0.00355709281745305 | BEFREE;LHGDN |
| 3667 | IRS1 | C0242379 | Malignant neoplasm of lung | 0.0029564820917142 | BEFREE;GAD |
| 3667 | IRS1 | C0271650 | Impaired glucose tolerance | 0.0029564820917142 | BEFREE;GAD |
| 3667 | IRS1 | C0342541 | Precocious pubarche | 0.0029564820917142 | BEFREE;GAD |
| 3667 | IRS1 | C0009404 | Colorectal Neoplasms | 0.00273291246481375 | LHGDN |
| 3667 | IRS1 | C0041341 | Tuberous Sclerosis | 0.00273291246481375 | LHGDN |
| 3667 | IRS1 | C0009402 | Colorectal Carcinoma | 0.0024725410579179 | BEFREE |
| 3667 | IRS1 | C0005684 | Malignant neoplasm of urinary bladder | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0008495 | Chorioamnionitis | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0014170 | Endometrial Neoplasms | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0015695 | Fatty Liver | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0015944 | Fetal Membranes, Premature Rupture | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0021368 | Inflammation | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0022876 | Premature Obstetric Labor | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0023895 | Liver diseases | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0024117 | Chronic Obstructive Airway Disease | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0026764 | Multiple Myeloma | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0036341 | Schizophrenia | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0085207 | Gestational Diabetes | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0151526 | Premature Birth | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0920269 | Microsatellite Instability | 0.002407028523288 | GAD |
| 3667 | IRS1 | C2919032 | Infection of amniotic sac and membranes | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0001418 | Adenocarcinoma | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0001627 | Congenital adrenal hyperplasia | 0.002407028523288 | GAD |
| 3667 | IRS1 | C0027627 | Neoplasm Metastasis | 0.0019230874894917 | BEFREE |
| 3667 | IRS1 | C0025149 | Medulloblastoma | 0.0013736339210655 | BEFREE |
| 3667 | IRS1 | C0699790 | Colon Carcinoma | 0.0013736339210655 | BEFREE |
| 3667 | IRS1 | C0020456 | Hyperglycemia | 0.0010989071368524 | BEFREE |
| 3667 | IRS1 | C0178874 | Tumor Progression | 0.0010989071368524 | BEFREE |
| 3667 | IRS1 | C0242339 | Dyslipidemias | 0.0010989071368524 | BEFREE |
| 3667 | IRS1 | C0600139 | Prostate carcinoma | 0.0010989071368524 | BEFREE |
| 3667 | IRS1 | C0497406 | Overweight | 0.0008241803526393 | BEFREE |
| 3667 | IRS1 | C0684249 | Carcinoma of lung | 0.0008241803526393 | BEFREE |
| 3667 | IRS1 | C3887505 | DYSFUNCTION - SKIN DISORDERS | 0.0008241803526393 | BEFREE |
| 3667 | IRS1 | C0002726 | Amyloidosis | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0003850 | Arteriosclerosis | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0004135 | Ataxia Telangiectasia | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0004153 | Atherosclerosis | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0007131 | Non-Small Cell Lung Carcinoma | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0023903 | Liver neoplasms | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0025517 | Metabolic Diseases | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0029463 | Osteosarcoma | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0029925 | Ovarian Carcinoma | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0085580 | Essential Hypertension | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0235974 | Pancreatic carcinoma | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0332996 | Persistent embryonic structure | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0338656 | Impaired cognition | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0346647 | Malignant neoplasm of pancreas | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0585442 | Osteosarcoma of bone | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0699791 | Stomach Carcinoma | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C1140680 | Malignant neoplasm of ovary | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C1306460 | Primary malignant neoplasm of lung | 0.0005494535684262 | BEFREE |
| 3667 | IRS1 | C0003872 | Arthritis, Psoriatic | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0007113 | Rectal Carcinoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0007124 | Noninfiltrating Intraductal Carcinoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0008626 | Congenital chromosomal disease | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0009241 | Cognition Disorders | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0010278 | Craniosynostosis | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0017636 | Glioblastoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0019158 | Hepatitis | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0019159 | Hepatitis A | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0019348 | Herpes Simplex Infections | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0020474 | Hyperlipidemia, Familial Combined | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0020557 | Hypertriglyceridemia | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0024623 | Malignant neoplasm of stomach | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0025202 | melanoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0027819 | Neuroblastoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0035335 | Retinoblastoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0035412 | Rhabdomyosarcoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0038013 | Ankylosing spondylitis | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0038868 | Progressive supranuclear palsy | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0040100 | Thymoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0085109 | Corneal Neovascularization | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0085631 | Agitation | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0151514 | Atrophic condition of skin | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0155626 | Acute myocardial infarction | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0175704 | LEOPARD Syndrome | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0206686 | Adrenocortical carcinoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0236642 | Pick Disease of the Brain | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0280100 | solid tumor | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0342782 | Depletion of mitochondrial DNA | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0393570 | Corticobasal degeneration | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0424295 | Hyperactive behavior | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0494165 | Secondary malignant neoplasm of liver | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0577631 | Carotid Atherosclerosis | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0596263 | Carcinogenesis | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0598935 | Tumor Initiation | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0700095 | Central neuroblastoma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0812413 | Malignant Pleural Mesothelioma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0856169 | Endothelial dysfunction | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0919267 | ovarian neoplasm | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0948089 | Acute Coronary Syndrome | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0949664 | Tauopathies | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C1292778 | Chronic myeloproliferative disorder | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C1302401 | Adenoma of large intestine | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C1318485 | Liver regeneration disorder | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C1377913 | Pleural Mesothelioma | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C1519670 | Tumor Angiogenesis | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C1569637 | Adenocarcinoma, Endometrioid | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C2711227 | Steatohepatitis | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C2936179 | Obesity, Visceral | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C3714619 | Insulin resistance syndrome | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C3887611 | Restlessness | 0.0002747267842131 | BEFREE |
| 3667 | IRS1 | C0001430 | Adenoma | 0.0002747267842131 | BEFREE |