Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
ABL2	PCA, Protein-peptide, Two-hybrid, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.59	BioGRID, IntAct, MINT
ANKS1A	Affinity Capture-Luminescence, PCA, Protein-peptide, Two-hybrid, anti tag coimmunoprecipitation, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.66	BioGRID, IntAct, MINT
ANKS1B	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
ANXA1	Affinity Capture-MS, anti tag coimmunoprecipitation, imaging technique, tandem affinity purification, ubiquitin reconstruction	association, colocalization, physical, physical association	15581623, 20029029, 24189400	0.70	BioGRID, IntAct, MINT
AOPEP	two hybrid array	physical association	24412244	0.37	IntAct, MINT
APBA3	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
APBB1	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
APBB2	Affinity Capture-Luminescence, PCA, Protein-peptide, Two-hybrid, luminescence based mammalian interactome mapping, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.66	BioGRID, IntAct, MINT
APBB3	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
APPL1	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
BLK	Affinity Capture-Luminescence, PCA, Protein-peptide, Two-hybrid, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.59	BioGRID, IntAct, MINT
BMX	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
CAPN7	fluorescence microscopy	colocalization	24953135	0.27	IntAct, MINT
CBL	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Co-crystal Structure, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, far western blotting, fluorescence microscopy, isothermal titration calorimetry, pull down, x-ray crystallography	association, colocalization, direct interaction, physical, physical association	10086340, 10428778, 10635327, 11239464, 11370743, 11408594, 12061819, 12593795, 12604776, 12734385, 12803489, 14505571, 14627991, 15107835, 15117950, 15159412, 15210722, 15282549, 15383614, 15465819, 15657067, 15668240, 15677445, 15735736, 15962011, 16105874, 16246327, 16729043, 16849543, 16914641, 16923119, 16969069, 17182860, 17242169, 17486068, 17545148, 17880946, 17971399, 17995934, 18271526, 18273061, 18316398, 18508924, 19155296, 19225046, 19531499, 19578043, 19713535, 19836242, 19947936, 20124286, 20308550, 20562913, 20877636, 20940296, 21772844, 22203672, 22266821, 22394513, 22591401, 22833562, 22976291, 23153581, 23158001, 23175185, 23418353, 23457600, 23774213, 23799367, 23897813, 24714105, 24797263, 25140053, 25521828, 25872741, 26055326, 26177020, 27059931, 28198003, 28791635, 7592693, 7657591, 7782294, 8662998, 9121472, 9130710, 9756944	0.96	BioGRID, IntAct, MINT
CISH	Affinity Capture-Luminescence, PCA, Protein-peptide, Two-hybrid, luminescence based mammalian interactome mapping, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.66	BioGRID, IntAct, MINT
CLNK	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
CMTM8	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence microscopy	colocalization, physical association	16263120	0.56	IntAct, MINT
CRK	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, PCA, Protein-peptide, Two-hybrid, luminescence based mammalian interactome mapping, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	10595738, 16273093, 16729043, 24658140, 25402006, 9617486, 9642287	0.51, 0.59	BioGRID, IntAct, MINT
CRKL	Affinity Capture-Luminescence, Affinity Capture-MS, PCA, Two-hybrid, proximity ligation assay, pull down, ubiquitin reconstruction	physical, physical association	16729043, 18271526, 23397142, 24658140, 25402006	0.69	BioGRID, IntAct, MINT
CSK	Affinity Capture-Luminescence, Affinity Capture-MS, PCA, Two-hybrid, pull down, ubiquitin reconstruction	physical, physical association	16729043, 24658140, 24797263, 25402006	0.57	BioGRID, IntAct, MINT
CYLC2	two hybrid array	physical association	24412244	0.37	IntAct, MINT
DNAJC13	Affinity Capture-MS, fluorescence microscopy	colocalization, physical	21510942, 28065597	0.27	BioGRID, IntAct, MINT
DOK4	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
DOK5	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
DOK6	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
EEA1	fluorescence microscopy	colocalization	22971756, 24597955	0.43	IntAct, MINT
EGF	Affinity Capture-Luminescence, Affinity Capture-MS, Co-crystal Structure, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, fluorescence-activated cell sorting, molecular sieving, proximity ligation assay, saturation binding, scintillation proximity assay, surface plasmon resonance, transmission electron microscopy, x ray scattering, x-ray crystallography	direct interaction, physical, physical association	10085134, 12093292, 12297050, 12620237, 17697999, 18271526, 19531499, 21439278, 21822280, 22729867, 23597562, 25080504, 25241761, 25453753, 26280537, 2790960	0.96	BioGRID, IntAct, MINT
ERBB2	Affinity Capture-MS, Affinity Capture-Western, Co-localization, anti bait coimmunoprecipitation, beta galactosidase complementation, protein cross-linking with a bifunctional reagent, protein kinase assay, proximity ligation assay, pull down, tandem affinity purification	association, physical, physical association	10572067, 11408594, 15657067, 16207817, 16516204, 16843263, 17148612, 17307140, 17486068, 18803307, 19060928, 19650109, 20211985, 21044682, 21203579, 21278786, 23436906, 23866081, 24189400, 24557338, 25241761	0.96	BioGRID, IntAct, MINT
ESR1	Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation	physical, physical association	17284441, 20935677, 28065597	0.40, 0.52	BioGRID, IntAct, MINT
FANCC	two hybrid array	physical association	24412244	0.37	IntAct, MINT
FES	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
FRAT2	two hybrid array	physical association	24412244	0.37	IntAct, MINT
GAB2	anti tag coimmunoprecipitation	association	16253990, 19172738	0.53	IntAct, MINT
GRB10	PCA, Reconstituted Complex, Two-hybrid, pull down, two hybrid, ubiquitin reconstruction	direct interaction, physical, physical association	24658140, 25402006, 9506989	0.65	BioGRID, IntAct, MINT
GRB2	Affinity Capture-MS, Affinity Capture-Western, PCA, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, competition binding, protein array, pull down, surface plasmon resonance, tandem affinity purification, ubiquitin reconstruction	association, direct interaction, physical, physical association	10026169, 10085134, 10229072, 10595738, 11370743, 11408594, 11896612, 11960376, 12577067, 1322798, 14679214, 15657067, 16273093, 16729043, 16799092, 17242169, 17971399, 18271526, 19254954, 19289468, 19531499, 19836242, 20124286, 20473329, 21278786, 21278788, 21596750, 21706016, 23178716, 23799367, 23956138, 24189400, 24658140, 24797263, 25402006, 27059931, 7506413, 7510700, 7518560, 7527043, 7592693, 7650032, 8647858, 8662998, 8810340, 8887653, 8940013, 9020117, 9050991, 9416834, 9886492	0.98	BioGRID, IntAct, MINT
GRK2 	anti tag coimmunoprecipitation, imaging technique	colocalization, physical association	15620700	0.46	IntAct, MINT
HEMGN	two hybrid array	physical association	24412244	0.37	IntAct, MINT
IRS1	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
IRS4	Affinity Capture-MS, Protein-peptide, protein array	direct interaction, physical	16273093, 24797263	0.44	BioGRID, IntAct, MINT
JAK2	Affinity Capture-Western, Biochemical Activity, Protein-peptide, protein array	direct interaction, physical	10358079, 16273093, 23838182	0.44	BioGRID, IntAct, MINT
KPNA1	anti bait coimmunoprecipitation	physical association	20692258	0.40	IntAct, MINT
LAMP1	fluorescence microscopy	colocalization	21510942, 24597955	0.43	IntAct, MINT
MAPK8IP1	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
MAPK8IP2	PCA, Protein-peptide, Two-hybrid, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.59	BioGRID, IntAct, MINT
MAPKAPK3	two hybrid array	physical association	24412244	0.37	IntAct, MINT
MUC1	Affinity Capture-Luminescence, Affinity Capture-Western, Biochemical Activity, Co-localization, PCA, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, cross-linking study, luminescence based mammalian interactome mapping, ubiquitin reconstruction	physical, physical association	11278868, 11483589, 16983337, 21258405, 24658140, 25402006	0.77	BioGRID, IntAct, MINT
NANS	two hybrid array	physical association	24412244	0.37	IntAct, MINT
NCK1	Affinity Capture-Western, PCA, Protein-peptide, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	10026169, 1333047, 16273093, 24658140, 25402006, 8662998, 9362449	0.70	BioGRID, IntAct, MINT
NUMB 	protein array	direct interaction	16273093	0.44	IntAct, MINT
NUMBL	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
PDCD6IP	Affinity Capture-Luminescence, Affinity Capture-Western, PCA, Two-hybrid, anti bait coimmunoprecipitation, ubiquitin reconstruction	physical, physical association	12771190, 15456872, 15557335, 24658140, 25402006	0.57	BioGRID, IntAct, MINT
PIK3R1	Affinity Capture-MS, Affinity Capture-Western, Co-localization, Protein-peptide, coimmunoprecipitation, competition binding, protein array, proximity ligation assay	association, direct interaction, physical, physical association	16273093, 19531499, 21701776, 25241761, 7797556, 8662998	0.78	BioGRID, IntAct, MINT
PIK3R2	Affinity Capture-MS, PCA, Protein-peptide, Reconstituted Complex, Two-hybrid, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	1334406, 16273093, 19531499, 23956138, 24658140, 25402006	0.59	BioGRID, IntAct, MINT
PIK3R3	Co-localization, PCA, Protein-peptide, Two-hybrid, protein array, proximity ligation assay, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25241761, 25402006	0.70	BioGRID, IntAct, MINT
PLCG1	Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, coimmunoprecipitation, cross-linking study, far western blotting, protein array, pull down	association, direct interaction, physical, physical association	11983899, 12061819, 12803489, 14568990, 16273093, 19605547, 24797263, 7693694, 7993895, 9020117, 9207933, 9756944	0.85	BioGRID, IntAct, MINT
PLCG2	Affinity Capture-Luminescence, Co-localization, PCA, Protein-peptide, Two-hybrid, luminescence based mammalian interactome mapping, protein array, proximity ligation assay, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25241761, 25402006	0.74	BioGRID, IntAct, MINT
PPP2CB	two hybrid array	physical association	24412244	0.37	IntAct, MINT
PTK6	Affinity Capture-Western, Protein-peptide, protein array	direct interaction, physical	16273093, 8940083	0.44	BioGRID, IntAct, MINT
PTPN1	Affinity Capture-Luminescence, Biochemical Activity, Co-crystal Structure, PCA, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence microscopy, protein kinase assay, ubiquitin reconstruction	colocalization, phosphorylation reaction, physical, physical association	10889023, 24658140, 25402006, 25796184, 7693694, 8621392, 9050838, 9355745	0.82	BioGRID, IntAct, MINT
PTPN11	Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Protein-peptide, Two-hybrid, protein array, pull down	direct interaction, physical, physical association	16273093, 16729043, 20473329, 28065597, 7673163, 8959326, 9756944	0.61	BioGRID, IntAct, MINT
PTPN2	Affinity Capture-Western, genetic interference	genetic interaction, physical	11514572, 15592458	0.17	BioGRID, IntAct, MINT
PTPN6	Affinity Capture-Western, Reconstituted Complex, Two-hybrid, pull down	association, physical	28065597, 7673163, 9733788	0.35	BioGRID, IntAct, MINT
RAPH1	anti bait coimmunoprecipitation	physical association	24076656	0.40	IntAct, MINT
RASA1	Protein-peptide, Reconstituted Complex, protein array	direct interaction, physical	1385407, 16273093, 8647858	0.44	BioGRID, IntAct, MINT
RIN2	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
SH2B1	PCA, Protein-peptide, Two-hybrid, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.59	BioGRID, IntAct, MINT
SH2B3	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
SH2D1A	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
SH2D2A	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
SH3BGRL	Affinity Capture-MS, pull down, ubiquitin reconstruction	physical, physical association	16729043, 20029029	0.57	BioGRID, IntAct, MINT
SH3GL2	Affinity Capture-Luminescence, Affinity Capture-Western, PCA, Two-hybrid, anti bait coimmunoprecipitation, ubiquitin reconstruction	physical, physical association	11894095, 15456872, 24658140, 24854121, 25402006	0.57	BioGRID, IntAct, MINT
SH3KBP1	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical, physical association	11894095, 12177062, 12734385, 12771190, 15456872, 16849543, 21635887	0.62	BioGRID, IntAct, MINT
SHC1	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, PCA, Protein-peptide, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, competition binding, experimental interaction detection, luminescence based mammalian interactome mapping, protein array, protein kinase assay, pull down, tandem affinity purification, ubiquitin reconstruction, x-ray crystallography	association, direct interaction, phosphorylation reaction, physical, physical association	10049786, 10595738, 10635327, 10766863, 11370743, 11408594, 15657067, 16273093, 16729043, 18271526, 19531499, 20473329, 20935677, 21278788, 23178716, 23799367, 23956138, 24189400, 24430869, 24658140, 24797263, 25402006, 26551075, 28065597, 7506413, 7518560, 7542744, 8034616, 8662998, 8810340, 9130710, 9544989, 9756944	0.58, 0.97	BioGRID, IntAct, MINT
SHC2	Affinity Capture-Western, Protein-peptide, protein array	direct interaction, physical	16273093, 24430869	0.44	BioGRID, IntAct, MINT
SHC3	Affinity Capture-Western, Protein-peptide, Reconstituted Complex, protein array	direct interaction, physical	16273093, 8662772, 9507002	0.44	BioGRID, IntAct, MINT
SLA	PCA, Protein-peptide, Two-hybrid, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.59	BioGRID, IntAct, MINT
SRC	Affinity Capture-Western, PCA, Two-hybrid, anti bait coimmunoprecipitation, ubiquitin reconstruction	association, physical, physical association	10358079, 10777553, 10971656, 17158602, 17284441, 20333651, 20624308, 20935677, 21268077, 21278788, 21573184, 23175185, 24189400, 24658140, 25402006, 28065597	0.82	BioGRID, IntAct, MINT
STAT1	Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, PCA, Two-hybrid, anti tag coimmunoprecipitation, competition binding, electrophoretic mobility shift assay, luminescence based mammalian interactome mapping, ubiquitin reconstruction	association, physical, physical association	10358079, 12070153, 15284024, 23956138, 24658140, 24797263, 25402006	0.71	BioGRID, IntAct, MINT
STAT3 	anti bait coimmunoprecipitation, fluorescence microscopy, proximity ligation assay, pull down, tandem affinity purification, ubiquitin reconstruction	association, colocalization, physical association	14966128, 15657067, 24135280, 24189400, 24658140, 25241761	0.89	IntAct, MINT
STAT5B	Affinity Capture-Western, Co-localization, pull down	physical, physical association	10558875, 16729043, 22729867	0.40	BioGRID, IntAct, MINT
STX17 	two hybrid array	physical association	24412244	0.37	IntAct, MINT
SYK	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
TGFB1	two hybrid array	physical association	24412244	0.37	IntAct, MINT
TLN1	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
TLR2	PCA, Two-hybrid, anti bait coimmunoprecipitation, ubiquitin reconstruction	physical, physical association	17126326, 24658140, 25402006	0.57	BioGRID, IntAct, MINT
TLR4	anti bait coimmunoprecipitation	physical association	17126326	0.40	IntAct, MINT
TNS4	Protein-peptide, protein array	direct interaction, physical	16273093	0.44	BioGRID, IntAct, MINT
TOM1L1	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, fluorescence microscopy	colocalization, physical, physical association	19798056	0.56	BioGRID, IntAct, MINT
TRMO 	two hybrid array	physical association	24412244	0.37	IntAct, MINT
TSTD2	two hybrid array	physical association	24412244	0.37	IntAct, MINT
VAV2	Affinity Capture-MS, Affinity Capture-Western, pull down	association, physical	10938113, 12454019, 18271526, 19531499, 20940296, 24797263	0.35	BioGRID, IntAct, MINT
VPS33B	fluorescence microscopy	colocalization	22677173	0.27	IntAct, MINT
ZAP70	Affinity Capture-Luminescence, PCA, Protein-peptide, Two-hybrid, protein array, ubiquitin reconstruction	direct interaction, physical, physical association	16273093, 24658140, 25402006	0.59	BioGRID, IntAct, MINT
ZNF510	two hybrid array	physical association	24412244	0.37	IntAct, MINT