Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
ARHGAP5	675	COSM5009248,	large_intestine	carcinoma	p.R1366H	Substitution - Missense	14:32152444-32152444,	PATHOGENIC	0.99833	24951259
ARHGAP5	675	COSM5009247,	large_intestine	carcinoma	p.E613*	Substitution - Nonsense	14:32092506-32092506,	PATHOGENIC	0.99668	24951259
ARHGAP5	675	COSM1607614,	liver	carcinoma	p.A288S	Substitution - Missense	14:32091531-32091531,	PATHOGENIC	0.97787	Info_not_available
ARHGAP5	675	COSM40805,	central_nervous_system	glioma	p.S1124L	Substitution - Missense	14:32094040-32094040,	PATHOGENIC	0.96161	18772396
ARHGAP5	675	COSM5027846,	breast	carcinoma	p.R867*	Substitution - Nonsense	14:32093268-32093268,	PATHOGENIC	0.94814	22722193
ARHGAP5	675	COSM5009246,	large_intestine	carcinoma	p.I79L	Substitution - Missense	14:32090904-32090904,	PATHOGENIC	0.89976	24951259
ARHGAP5	675	COSM4651201,	large_intestine	carcinoma	p.Y1387Y	Substitution - coding silent	14:32152508-32152508,	NEUTRAL	0.01066	24951259
ARHGAP5	675	COSM5027845,	breast	carcinoma	p.N396fs*8	Deletion - Frameshift	14:32091852-32091858,	Info_not_available	Info_not_available	22722193
ARHGAP5	675	COSM5009683, COSM5010280, COSM5010321,	large_intestine	carcinoma	p.E956E, p.R1149fs*74, p.S58fs*1	Deletion - Frameshift, Insertion - Frameshift, Substitution - coding silent	14:32090838-32090839, 14:32093537-32093537, 14:32094112-32094112,	Info_not_available	0.55287, Info_not_available	24951259